IXOSC|EnsemblGenome=LOC8040945|UniProtKB=A0ACM8E5S6 A0ACM8E5S6 LOC8040945 PTHR28659:SF2 RETICULON-LIKE PROTEIN RETREG1-3_ARL6IP-LIKE N-TERMINAL RETICULON-HOMOLOGY DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052129|UniProtKB=A0ACM8DU76 A0ACM8DU76 LOC8052129 PTHR12984:SF6 SCY1-RELATED S/T PROTEIN KINASE-LIKE SCY1-LIKE PROTEIN 2 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120841875|UniProtKB=A0ACM8ESQ1 A0ACM8ESQ1 pds5 PTHR12663:SF0 ANDROGEN INDUCED INHIBITOR OF PROLIFERATION AS3 / PDS5-RELATED PRECOCIOUS DISSOCIATION OF SISTERS 5, ISOFORM A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121835342|UniProtKB=A0ACM8FTL3 A0ACM8FTL3 LOC121835342 PTHR12265:SF30 TRANSMEMBRANE PROTEIN 53 TRANSMEMBRANE PROTEIN 53 IXOSC|EnsemblGenome=LOC115313565|UniProtKB=A0ACM8F5S8 A0ACM8F5S8 LOC115313565 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115315082|UniProtKB=A0ACM8F450 A0ACM8F450 eIF3i PTHR19877:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I translation initiation factor activity#GO:0003743;RNA binding#GO:0003723;translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC115325269|UniProtKB=A0ACM8E0H1 A0ACM8E0H1 LOC115325269 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8035873|UniProtKB=A0ACM8F5Q1 A0ACM8F5Q1 PTHR21664:SF1 CHRONIC MYELOGENOUS LEUKEMIA TUMOR ANTIGEN 66 NUDC DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8053152|UniProtKB=A0ACM8E289 A0ACM8E289 LOC8053152 PTHR24157:SF4 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 CELL PATTERN FORMATION-ASSOCIATED PROTEIN STUA IXOSC|EnsemblGenome=LOC115318003|UniProtKB=A0ACM8FE09 A0ACM8FE09 LOC115318003 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC121838229|UniProtKB=A0ACM8G794 A0ACM8G794 LOC121838229 PTHR33198:SF22 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322977|UniProtKB=A0ACM8EWR4 A0ACM8EWR4 LOC115322977 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121835853|UniProtKB=A0ACM8FW25 A0ACM8FW25 LOC121835853 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840320|UniProtKB=A0ACM8EPS2 A0ACM8EPS2 LOC120840320 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311829|UniProtKB=A0ACM8DRA8 A0ACM8DRA8 LOC115311829 PTHR11387:SF2 CYTOCHROME C OXIDASE SUBUNIT 6B CYTOCHROME C OXIDASE SUBUNIT 6B1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC8037019|UniProtKB=A0ACM8E0T0 A0ACM8E0T0 LOC8037019 PTHR28680:SF2 CENTROMERE PROTEIN X CENTROMERE PROTEIN X reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;meiosis I#GO:0007127;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;reproductive process#GO:0022414;homologous recombination#GO:0035825;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;resolution of meiotic recombination intermediates#GO:0000712;organelle organization#GO:0006996;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;Fanconi anaemia nuclear complex#GO:0043240;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC8038274|UniProtKB=A0ACM8E507 A0ACM8E507 LOC8038274 PTHR15644:SF2 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 OSTEOPETROSIS ASSOCIATED TRANSMEMBRANE PROTEIN 1 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8041788|UniProtKB=A0ACM8F661 A0ACM8F661 Oda PTHR10279:SF10 ORNITHINE DECARBOXYLASE ANTIZYME ORNITHINE DECARBOXYLASE ANTIZYME molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120840886|UniProtKB=A0ACM8ERG0 A0ACM8ERG0 LOC120840886 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8025016|UniProtKB=A0ACM8G700 A0ACM8G700 IA-2 PTHR46106:SF4 IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C IA-2 PROTEIN TYROSINE PHOSPHATASE, ISOFORM C regulation of biological process#GO:0050789;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of secretion#GO:0051046 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell junction#GO:0030054;vesicle#GO:0031982;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;synapse#GO:0045202;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC120840954|UniProtKB=A0ACM8G3K0 A0ACM8G3K0 LOC120840954 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120849344|UniProtKB=A0ACM8F7P0 A0ACM8F7P0 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121833158|UniProtKB=A0ACM8FKM0 A0ACM8FKM0 LOC121833158 PTHR24256:SF470 TRYPTASE-RELATED SERINE PROTEASE 33 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120848543|UniProtKB=A0ACM8F529 A0ACM8F529 PTHR14191:SF3 PDZ DOMAIN CONTAINING PROTEIN GH04176P-RELATED protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cellular process#GO:0009987 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8031981|UniProtKB=A0ACM8DJ22 A0ACM8DJ22 LOC8031981 PTHR11136:SF5 FOLYLPOLYGLUTAMATE SYNTHASE-RELATED FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ligase#PC00142 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate synthase#P02958;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943 IXOSC|EnsemblGenome=LOC115309896|UniProtKB=A0ACM8G3Z5 A0ACM8G3Z5 LOC115309896 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115324216|UniProtKB=A0ACM8EJL3 A0ACM8EJL3 LOC115324216 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8041550|UniProtKB=A0ACM8DZ92 A0ACM8DZ92 LOC8041550 PTHR12933:SF0 ORF PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 25 HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;rRNA binding#GO:0019843;RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121837515|UniProtKB=A0ACM8G533 A0ACM8G533 LOC121837515 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8027744|UniProtKB=A0ACM8F474 A0ACM8F474 PTHR45953:SF1 IDURONATE 2-SULFATASE IDURONATE 2-SULFATASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;lysosome#GO:0005764 IXOSC|EnsemblGenome=LOC120838929|UniProtKB=A0ACM8ELP5 A0ACM8ELP5 LOC120838929 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042016|UniProtKB=A0ACM8FGL7 A0ACM8FGL7 LOC8042016 PTHR15744:SF0 BLOM7 KH HOMOLOGY DOMAIN-CONTAINING PROTEIN 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;mRNA splice site recognition#GO:0006376;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115313149|UniProtKB=A0ACM8DSH2 A0ACM8DSH2 LOC115313149 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8039124|UniProtKB=A0ACM8E1Y4 A0ACM8E1Y4 LOC8039124 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 IXOSC|EnsemblGenome=LOC8033753|UniProtKB=A0ACM8G0Q4 A0ACM8G0Q4 LOC8033753 PTHR14042:SF24 DOPEY-RELATED PROTEIN DOP1 HOMOLOG endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;retrograde transport, vesicle recycling within Golgi#GO:0000301 Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 IXOSC|EnsemblGenome=LOC8028181|UniProtKB=A0ACM8EYM5 A0ACM8EYM5 LOC8028181 PTHR10027:SF41 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN SLOWPOKE 2, ISOFORM D monoatomic ion-gated channel activity#GO:0022839;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;ligand-gated monoatomic ion channel activity#GO:0015276;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC115332846|UniProtKB=A0ACM8F2M2 A0ACM8F2M2 LOC115332846 PTHR46199:SF3 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;spindle organization#GO:0007051;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;cell division#GO:0051301;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;intracellular signaling cassette#GO:0141124;cellular component assembly#GO:0022607;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;cytoskeleton-dependent cytokinesis#GO:0061640;Rho protein signal transduction#GO:0007266;nuclear division#GO:0000280;cytokinesis#GO:0000910;signaling#GO:0023052;response to stimulus#GO:0050896;mitotic spindle organization#GO:0007052;regulation of biological process#GO:0050789;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694 midbody#GO:0030496;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;plasma membrane#GO:0005886;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;cleavage furrow#GO:0032154 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC115312545|UniProtKB=A0ACM8EUD8 A0ACM8EUD8 LOC115312545 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115323628|UniProtKB=A0ACM8FVH3 A0ACM8FVH3 spz6 PTHR23199:SF7 NEUROTROPHIN 1-RELATED RE45222P molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;defense response to other organism#GO:0098542;developmental process#GO:0032502;defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;response to external stimulus#GO:0009605;innate immune response#GO:0045087;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;central nervous system development#GO:0007417;response to stimulus#GO:0050896;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;system development#GO:0048731;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8033232|UniProtKB=A0ACM8EEN2 A0ACM8EEN2 LOC8033232 PTHR14167:SF48 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN 19 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115331014|UniProtKB=A0ACM8G2M7 A0ACM8G2M7 LOC115331014 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121046440|UniProtKB=A0ACM8FDX0 A0ACM8FDX0 LOC121046440 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120839663|UniProtKB=A0ACM8END1 A0ACM8END1 LOC120839663 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031023|UniProtKB=A0ACM8DZU8 A0ACM8DZU8 LKRSDH PTHR11133:SF28 SACCHAROPINE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE SYNTHASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8027631|UniProtKB=A0ACM8FJ03 A0ACM8FJ03 LOC8027631 PTHR24418:SF474 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 IXOSC|EnsemblGenome=LOC8030292|UniProtKB=A0ACM8DYX7 A0ACM8DYX7 LOC8030292 PTHR43084:SF1 PERSULFIDE DIOXYGENASE ETHE1 PERSULFIDE DIOXYGENASE ETHE1, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115329931|UniProtKB=A0ACM8FZ54 A0ACM8FZ54 LOC115329931 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8039067|UniProtKB=A0ACM8FLU1 A0ACM8FLU1 Br140 PTHR13793:SF169 PHD FINGER PROTEINS BROMODOMAIN-CONTAINING PROTEIN HOMOLOG chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121833129|UniProtKB=A0ACM8FIC3 A0ACM8FIC3 LOC121833129 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115327827|UniProtKB=A0ACM8FSW3 A0ACM8FSW3 LOC115327827 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115312780|UniProtKB=A0ACM8F8X8 A0ACM8F8X8 LOC115312780 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115327675|UniProtKB=A0ACM8EMD3 A0ACM8EMD3 LOC115327675 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120843665|UniProtKB=A0ACM8FFZ5 A0ACM8FFZ5 LOC120843665 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120840876|UniProtKB=A0ACM8EQH2 A0ACM8EQH2 LOC120840876 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120843991|UniProtKB=A0ACM8EYH5 A0ACM8EYH5 LOC120843991 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120846981|UniProtKB=A0ACM8F3R9 A0ACM8F3R9 mRpS25 PTHR13274:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN MS25 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120836712|UniProtKB=A0ACM8EGK9 A0ACM8EGK9 LOC120836712 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837571|UniProtKB=A0ACM8G517 A0ACM8G517 LOC121837571 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8026608|UniProtKB=A0ACM8G477 A0ACM8G477 DopEcR PTHR24248:SF172 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE_ECDYSTEROID RECEPTOR, ISOFORM A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120838351|UniProtKB=A0ACM8EJ15 A0ACM8EJ15 LOC120838351 PTHR48068:SF4 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933 SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234;peptidase complex#GO:1905368;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;acetyltransferase complex#GO:1902493;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;chromatin#GO:0000785 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 IXOSC|EnsemblGenome=LOC121837374|UniProtKB=A0ACM8G4D9 A0ACM8G4D9 LOC121837374 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120841013|UniProtKB=A0ACM8ERR7 A0ACM8ERR7 LOC120841013 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053216|UniProtKB=A0ACM8G3J3 A0ACM8G3J3 LOC8053216 PTHR11220:SF58 HEME-BINDING PROTEIN-RELATED SOUL HEME-BINDING FAMILY PROTEIN IXOSC|EnsemblGenome=LOC120842153|UniProtKB=A0ACM8EU96 A0ACM8EU96 LOC120842153 PTHR22930:SF269 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029551|UniProtKB=A0ACM8EH30 A0ACM8EH30 LOC8029551 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120849407|UniProtKB=A0ACM8F820 A0ACM8F820 LOC120849407 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837557|UniProtKB=A0ACM8EHM6 A0ACM8EHM6 LOC120837557 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037417|UniProtKB=A0ACM8F828 A0ACM8F828 Samuel PTHR12247:SF131 POLYCOMB GROUP PROTEIN MALIGNANT BRAIN TUMOR REPEAT PROTEIN 1-RELATED protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8041698|UniProtKB=A0ACM8EY41 A0ACM8EY41 LOC8041698 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115325748|UniProtKB=A0ACM8E629 A0ACM8E629 LOC115325748 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC120849460|UniProtKB=A0ACM8F7T4 A0ACM8F7T4 LOC120849460 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8043799|UniProtKB=A0ACM8EKU5 A0ACM8EKU5 PTHR10513:SF24 DEOXYNUCLEOSIDE KINASE THYMIDINE KINASE 2, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;deoxynucleoside kinase activity#GO:0019136 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8050789|UniProtKB=A0ACM8EUC9 A0ACM8EUC9 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121835564|UniProtKB=A0ACM8FU75 A0ACM8FU75 LOC121835564 PTHR10528:SF17 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER LILLI transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 nucleic acid biosynthetic process#GO:0141187;nervous system process#GO:0050877;RNA metabolic process#GO:0016070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;system process#GO:0003008;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;DNA-templated transcription elongation#GO:0006354;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;gene expression#GO:0010467;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8031974|UniProtKB=A0ACM8EBC0 A0ACM8EBC0 LOC8031974 PTHR12446:SF34 TESMIN/TSO1-RELATED PROTEIN LIN-54 HOMOLOG-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121833226|UniProtKB=A0ACM8FK02 A0ACM8FK02 LOC121833226 PTHR13707:SF23 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120836559|UniProtKB=A0ACM8EFB2 A0ACM8EFB2 LOC120836559 PTHR31879:SF2 DET1- AND DDB1-ASSOCIATED PROTEIN 1 DET1- AND DDB1-ASSOCIATED PROTEIN 1 positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 IXOSC|EnsemblGenome=LOC8029663|UniProtKB=A0ACM8DP99 A0ACM8DP99 LOC8029663 PTHR12783:SF6 RALA BINDING PROTEIN 1 RALBP1 RALA-BINDING PROTEIN 1 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;signaling#GO:0023052;response to stimulus#GO:0050896;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;vesicle-mediated transport#GO:0016192;signal transduction#GO:0007165;cellular process#GO:0009987 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC115317682|UniProtKB=A0ACM8F1G9 A0ACM8F1G9 LOC115317682 PTHR31716:SF1 PROTEIN FMC1 HOMOLOG PROTEIN FMC1 HOMOLOG organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121835885|UniProtKB=A0ACM8FW75 A0ACM8FW75 LOC121835885 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8036293|UniProtKB=A0ACM8DTD3 A0ACM8DTD3 Vps45 PTHR11679:SF3 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 45 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC115310340|UniProtKB=A0ACM8EMV0 A0ACM8EMV0 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8050447|UniProtKB=A0ACM8EDI2 A0ACM8EDI2 LOC8050447 PTHR46078:SF2 FORKHEAD BOX PROTEIN J2 FAMILY MEMBER FORK-HEAD DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC120836551|UniProtKB=A0ACM8EFD3 A0ACM8EFD3 LOC120836551 PTHR47972:SF45 KINESIN-LIKE PROTEIN KLP-3 PROTEIN CLARET SEGREGATIONAL microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC120844192|UniProtKB=A0ACM8EZ59 A0ACM8EZ59 LOC120844192 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8038645|UniProtKB=A0ACM8EBA0 A0ACM8EBA0 mRpL20 PTHR10986:SF16 39S RIBOSOMAL PROTEIN L20 LARGE RIBOSOMAL SUBUNIT PROTEIN BL20M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8024805|UniProtKB=A0ACM8DXM0 A0ACM8DXM0 LOC8024805 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115317531|UniProtKB=A0ACM8G3S7 A0ACM8G3S7 LOC115317531 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029137|UniProtKB=A0ACM8ECL6 A0ACM8ECL6 LOC8029137 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120840259|UniProtKB=A0ACM8ENH2 A0ACM8ENH2 LOC120840259 PTHR43725:SF58 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 epimerase/racemase#PC00096 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 IXOSC|EnsemblGenome=LOC121834418|UniProtKB=A0ACM8FPW6 A0ACM8FPW6 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115316324|UniProtKB=A0ACM8F097 A0ACM8F097 LOC115316324 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8023561|UniProtKB=A0ACM8DPS0 A0ACM8DPS0 LOC8023561 PTHR46115:SF1 THIOREDOXIN-LIKE PROTEIN 1 THIOREDOXIN-LIKE PROTEIN 1 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122 IXOSC|EnsemblGenome=LOC8030456|UniProtKB=A0ACM8EBT9 A0ACM8EBT9 LOC8030456 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120846264|UniProtKB=A0ACM8F1M9 A0ACM8F1M9 LOC120846264 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;purine-containing compound metabolic process#GO:0072521;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8034878|UniProtKB=A0ACM8FDW3 A0ACM8FDW3 LOC8034878 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594 transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916 cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC115324963|UniProtKB=A0ACM8FA09 A0ACM8FA09 LOC115324963 PTHR22891:SF111 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 nuclease activity#GO:0004518;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC115328958|UniProtKB=A0ACM8F1B4 A0ACM8F1B4 LOC115328958 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120840721|UniProtKB=A0ACM8EQ34 A0ACM8EQ34 LOC120840721 PTHR45632:SF36 LD33804P RING ZINC FINGER-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027926|UniProtKB=A0ACM8E871 A0ACM8E871 LOC8027926 PTHR13513:SF9 E3 UBIQUITIN-PROTEIN LIGASE UBR7 E3 UBIQUITIN-PROTEIN LIGASE UBR7-RELATED protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115322217|UniProtKB=A0ACM8G339 A0ACM8G339 LOC115322217 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8024480|UniProtKB=A0ACM8DIC7 A0ACM8DIC7 Exo70 PTHR12542:SF41 EXOCYST COMPLEX PROTEIN EXO70 EXOCYST COMPLEX COMPONENT 7 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179 cell cortex#GO:0005938;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;exocyst#GO:0000145;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8027132|UniProtKB=A0ACM8DQ12 A0ACM8DQ12 LOC8027132 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120848426|UniProtKB=A0ACM8F5Q8 A0ACM8F5Q8 LOC120848426 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115323603|UniProtKB=A0ACM8E338 A0ACM8E338 LOC115323603 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833817|UniProtKB=A0ACM8FN63 A0ACM8FN63 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=ISCI022186|UniProtKB=B7QDG3 B7QDG3 ISCW022186 PTHR13232:SF10 NAD(P)H-HYDRATE EPIMERASE NAD(P)H-HYDRATE EPIMERASE metabolite interconversion enzyme#PC00262;epimerase/racemase#PC00096 IXOSC|EnsemblGenome=LOC120846237|UniProtKB=A0ACM8F2R5 A0ACM8F2R5 LOC120846237 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121834747|UniProtKB=A0ACM8FPR4 A0ACM8FPR4 LOC121834747 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835732|UniProtKB=A0ACM8FVL4 A0ACM8FVL4 LOC121835732 PTHR11733:SF249 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED PEPTIDASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115310511|UniProtKB=A0ACM8G1G3 A0ACM8G1G3 LOC115310511 PTHR47972:SF45 KINESIN-LIKE PROTEIN KLP-3 PROTEIN CLARET SEGREGATIONAL microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC120846553|UniProtKB=A0ACM8F1V9 A0ACM8F1V9 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053616|UniProtKB=A0ACM8DM62 A0ACM8DM62 LOC8053616 PTHR14154:SF154 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER 2 transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;intracellular transport#GO:0046907;carboxylic acid transport#GO:0046942;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;organic acid transport#GO:0015849;transmembrane transport#GO:0055085;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;monocarboxylic acid transport#GO:0015718 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115329265|UniProtKB=A0ACM8E9A9 A0ACM8E9A9 HemK2 PTHR45875:SF1 METHYLTRANSFERASE N6AMT1 METHYLTRANSFERASE HEMK2 catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;catalytic complex#GO:1902494;transferase complex#GO:1990234 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115324245|UniProtKB=A0ACM8E4M7 A0ACM8E4M7 LOC115324245 PTHR12621:SF12 CYSTEINE AND HISTIDINE-RICH DOMAIN CHORD -CONTAINING PROTEIN CYSTEINE AND HISTIDINE-RICH DOMAIN-CONTAINING PROTEIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule organizing center organization#GO:0031023;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8031957|UniProtKB=A0ACM8EY28 A0ACM8EY28 LOC8031957 PTHR10625:SF53 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE HDAC1 catalytic activity#GO:0003824;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 negative regulation of cellular process#GO:0048523;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013 Wnt signaling pathway#P00057>Histone deacetylase#P01472 IXOSC|EnsemblGenome=LOC8034605|UniProtKB=A0ACM8E276 A0ACM8E276 LOC8034605 PTHR10966:SF0 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 protein binding#GO:0005515;binding#GO:0005488;transcription factor binding#GO:0008134 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 IXOSC|EnsemblGenome=LOC115330462|UniProtKB=A0ACM8F354 A0ACM8F354 LOC115330462 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8031181|UniProtKB=A0ACM8FT72 A0ACM8FT72 LOC8031181 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8051624|UniProtKB=A0ACM8DRC0 A0ACM8DRC0 LOC8051624 PTHR22775:SF52 SORTING NEXIN FI21262P1 anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol binding#GO:0035091;ion binding#GO:0043167 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121835073|UniProtKB=A0ACM8FSS8 A0ACM8FSS8 LOC121835073 PTHR10680:SF39 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 IXOSC|EnsemblGenome=LOC121837789|UniProtKB=A0ACM8G561 A0ACM8G561 LOC121837789 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837375|UniProtKB=A0ACM8G3D5 A0ACM8G3D5 LOC121837375 PTHR24416:SF655 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8041030|UniProtKB=A0ACM8EQR8 A0ACM8EQR8 LOC8041030 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transporter#PC00227 IXOSC|EnsemblGenome=LOC8026453|UniProtKB=A0ACM8F805 A0ACM8F805 LOC8026453 PTHR22918:SF6 SEMINAL PLASMA PROTEIN EG:8D8.1 PROTEIN-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120851161|UniProtKB=A0ACM8FBK2 A0ACM8FBK2 LOC120851161 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309782|UniProtKB=A0ACM8F489 A0ACM8F489 LOC115309782 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8035625|UniProtKB=A0ACM8E2L1 A0ACM8E2L1 Vta1 PTHR46009:SF1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VTA1 HOMOLOG late endosome to vacuole transport#GO:0045324;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120842166|UniProtKB=A0ACM8ET99 A0ACM8ET99 wap PTHR19919:SF0 WD REPEAT CONTAINING PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 7 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115310313|UniProtKB=A0ACM8FAM3 A0ACM8FAM3 LOC115310313 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024114|UniProtKB=A0ACM8EBE4 A0ACM8EBE4 LOC8024114 PTHR12953:SF0 MEMBRANE PROTEIN CH1 RELATED LD18032P membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 structural protein#PC00211 IXOSC|EnsemblGenome=LOC8051173|UniProtKB=A0ACM8DLV9 A0ACM8DLV9 LOC8051173 PTHR11780:SF10 NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1 NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8052374|UniProtKB=A0ACM8E2Q7 A0ACM8E2Q7 LOC8052374 PTHR10334:SF565 CYSTEINE-RICH SECRETORY PROTEIN-RELATED AT04879P-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8051784|UniProtKB=A0ACM8E2G6 A0ACM8E2G6 LOC8051784 PTHR12830:SF9 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell cycle phase transition#GO:1901987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;protein polyubiquitination#GO:0000209;protein K11-linked ubiquitination#GO:0070979;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;positive regulation of cellular component organization#GO:0051130;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of cell cycle#GO:0045787;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome segregation#GO:0051983;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC120842946|UniProtKB=A0ACM8EV30 A0ACM8EV30 LOC120842946 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115312879|UniProtKB=A0ACM8EKR1 A0ACM8EKR1 LOC115312879 PTHR12411:SF1033 CYSTEINE PROTEASE FAMILY C1-RELATED RE20049P-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8037051|UniProtKB=A0ACM8DVR8 A0ACM8DVR8 LOC8037051 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120840488|UniProtKB=A0ACM8G4H0 A0ACM8G4H0 LOC120840488 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115315266|UniProtKB=A0ACM8F5P1 A0ACM8F5P1 LOC115315266 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC115320539|UniProtKB=A0ACM8E0B0 A0ACM8E0B0 LOC115320539 PTHR43016:SF18 PRESEQUENCE PROTEASE PRESEQUENCE PROTEASE, MITOCHONDRIAL catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120846062|UniProtKB=A0ACM8FH53 A0ACM8FH53 LOC120846062 PTHR47333:SF9 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 1 ISOFORM X1 IXOSC|EnsemblGenome=LOC115330563|UniProtKB=A0ACM8EB50 A0ACM8EB50 LOC115330563 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311376|UniProtKB=A0ACM8DQM8 A0ACM8DQM8 PTHR11042:SF202 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EIF-2-ALPHA KINASE GCN2 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;cellular response to stress#GO:0033554;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;cellular response to amino acid starvation#GO:0034198 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121838469|UniProtKB=A0ACM8G935 A0ACM8G935 LOC121838469 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040089|UniProtKB=A0ACM8FBR2 A0ACM8FBR2 Utx PTHR14017:SF32 LYSINE-SPECIFIC DEMETHYLASE LD02225P RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;cis-regulatory region sequence-specific DNA binding#GO:0000987;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;sequence-specific double-stranded DNA binding#GO:1990837;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;chromatin DNA binding#GO:0031490;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;histone demethylase activity#GO:0032452 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8026411|UniProtKB=A0ACM8EAX4 A0ACM8EAX4 LOC8026411 PTHR11452:SF95 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8041857|UniProtKB=A0ACM8DKT6 A0ACM8DKT6 ND-18 PTHR12219:SF8 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;electron transport chain#GO:0022900;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular respiration#GO:0045333;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003 transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8025843|UniProtKB=A0ACM8DYD3 A0ACM8DYD3 Vps37B PTHR13678:SF27 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 LD45836P ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;localization within membrane#GO:0051668;establishment of protein localization to membrane#GO:0090150;protein targeting to vacuole#GO:0006623;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting to membrane#GO:0006612;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;cellular localization#GO:0051641;protein transport#GO:0015031;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;ESCRT I complex#GO:0000813;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC120841177|UniProtKB=A0ACM8EQZ6 A0ACM8EQZ6 LOC120841177 PTHR24264:SF87 TRYPSIN-RELATED SERINE PROTEASE 30 ISOFORM X1 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121837504|UniProtKB=A0ACM8G3R8 A0ACM8G3R8 LOC121837504 PTHR46379:SF1 ZINC FINGER MYND DOMAIN-CONTAINING ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8041044|UniProtKB=A0ACM8E7Z0 A0ACM8E7Z0 LOC8041044 PTHR46179:SF20 ZINC FINGER PROTEIN TRANSCRIPTION FACTOR IIIA regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115310656|UniProtKB=A0ACM8FLR5 A0ACM8FLR5 LOC115310656 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED transferase#PC00220;nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC121045961|UniProtKB=A0ACM8FCJ3 A0ACM8FCJ3 LOC121045961 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034206|UniProtKB=A0ACM8F1U2 A0ACM8F1U2 LOC8034206 PTHR48016:SF56 MAP KINASE KINASE KINASE SSK2-RELATED-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115318183|UniProtKB=A0ACM8ER09 A0ACM8ER09 LOC115318183 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8043730|UniProtKB=A0ACM8FJD0 A0ACM8FJD0 Epac PTHR23113:SF327 GUANINE NUCLEOTIDE EXCHANGE FACTOR EXCHANGE PROTEIN DIRECTLY ACTIVATED BY CAMP, ISOFORM E molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC120843470|UniProtKB=A0ACM8EXB3 A0ACM8EXB3 LOC120843470 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8031828|UniProtKB=A0ACM8DQ72 A0ACM8DQ72 LOC8031828 PTHR11592:SF135 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 oxidoreductase#PC00176;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC8044027|UniProtKB=A0ACM8E9G9 A0ACM8E9G9 LOC8044027 PTHR10997:SF8 IMPORTIN-7, 8, 11 EXPORTIN-2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;nuclear export#GO:0051168;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein export from nucleus#GO:0006611;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;cytosol#GO:0005829 transporter#PC00227 IXOSC|EnsemblGenome=LOC120844850|UniProtKB=A0ACM8EZS1 A0ACM8EZS1 LOC120844850 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8043830|UniProtKB=A0ACM8FIP7 A0ACM8FIP7 LOC8043830 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC8040822|UniProtKB=A0ACM8EK41 A0ACM8EK41 LOC8040822 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115317035|UniProtKB=A0ACM8DXA3 A0ACM8DXA3 LOC115317035 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115332399|UniProtKB=A0ACM8F2L2 A0ACM8F2L2 LOC115332399 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115332514|UniProtKB=A0ACM8F055 A0ACM8F055 LOC115332514 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115312059|UniProtKB=A0ACM8ETY9 A0ACM8ETY9 LOC115312059 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8053888|UniProtKB=A0ACM8EGK2 A0ACM8EGK2 LOC8053888 PTHR10110:SF126 SODIUM/HYDROGEN EXCHANGER NA(+)_H(+) EXCHANGER PROTEIN 7 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075 import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115308185|UniProtKB=A0ACM8DJJ8 A0ACM8DJJ8 LOC115308185 PTHR20934:SF0 TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG TRANSCRIPTION ELONGATION FACTOR 1 HOMOLOG binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC8032236|UniProtKB=A0ACM8DJB6 A0ACM8DJB6 LOC8032236 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC115315839|UniProtKB=A0ACM8DVB4 A0ACM8DVB4 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I acyltransferase activity#GO:0016746;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 metabolic process#GO:0008152;regulation of gene expression#GO:0010468;protein sumoylation#GO:0016925;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;post-translational protein modification#GO:0043687;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;protein modification by small protein conjugation or removal#GO:0070647;regulation of RNA metabolic process#GO:0051252;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;chromosome#GO:0005694;organelle lumen#GO:0043233 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 IXOSC|EnsemblGenome=LOC8041858|UniProtKB=A0ACM8F4S9 A0ACM8F4S9 LOC8041858 PTHR44329:SF298 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED SERINE_THREONINE-PROTEIN KINASE DRKD-RELATED catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8038633|UniProtKB=A0ACM8EBA7 A0ACM8EBA7 LOC8038633 PTHR46337:SF1 RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN RCC1-LIKE G EXCHANGING FACTOR-LIKE PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;cellular component organization or biogenesis#GO:0071840;mitochondrial ribosome assembly#GO:0061668;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;ribonucleoprotein complex biogenesis#GO:0022613 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115329927|UniProtKB=A0ACM8EB19 A0ACM8EB19 LOC115329927 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8026387|UniProtKB=A0ACM8DHR4 A0ACM8DHR4 Trmt112 PTHR12773:SF0 UPF0315 PROTEIN-RELATED MULTIFUNCTIONAL METHYLTRANSFERASE SUBUNIT TRM112-LIKE PROTEIN enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115324737|UniProtKB=A0ACM8E4Z3 A0ACM8E4Z3 LOC115324737 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032668|UniProtKB=A0ACM8EE51 A0ACM8EE51 LOC8032668 PTHR43243:SF108 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 amino acid transporter#PC00046;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121836616|UniProtKB=A0ACM8FZC8 A0ACM8FZC8 LOC121836616 PTHR21661:SF35 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE catalytic activity#GO:0003824;ether hydrolase activity#GO:0016803;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8053937|UniProtKB=A0ACM8G4V1 A0ACM8G4V1 LOC8053937 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8037629|UniProtKB=A0ACM8EL13 A0ACM8EL13 LOC8037629 PTHR11373:SF4 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE FALTEN, ISOFORM B hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121833548|UniProtKB=A0ACM8FLC1 A0ACM8FLC1 LOC121833548 PTHR12101:SF1 POPEYE DOMAIN CONTAINING PROTEIN BVES nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076 muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;multicellular organismal process#GO:0032501;heart development#GO:0007507;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of membrane potential#GO:0042391;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;striated muscle cell differentiation#GO:0051146 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;apical junction complex#GO:0043296;tight junction#GO:0070160;cell junction#GO:0030054;sarcolemma#GO:0042383;anchoring junction#GO:0070161 IXOSC|EnsemblGenome=LOC115309871|UniProtKB=A0ACM8EP83 A0ACM8EP83 LOC115309871 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8035719|UniProtKB=A0ACM8DJS4 A0ACM8DJS4 PTHR44298:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 DNAJ HOMOLOG SUBFAMILY B MEMBER 11 protein binding#GO:0005515;binding#GO:0005488 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120846499|UniProtKB=A0ACM8F1Q9 A0ACM8F1Q9 LOC120846499 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033971|UniProtKB=A0ACM8F5R3 A0ACM8F5R3 LOC8033971 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8034342|UniProtKB=A0ACM8DJ67 A0ACM8DJ67 PTHR43888:SF31 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ HOMOLOG SUBFAMILY A MEMBER 2 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515;ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular response to stress#GO:0033554;protein refolding#GO:0042026;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein folding#GO:0006457;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115329505|UniProtKB=A0ACM8FFQ5 A0ACM8FFQ5 LOC115329505 PTHR23287:SF16 RUBY-EYE2-LIKE PROTEIN TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN 2 IXOSC|EnsemblGenome=LOC120839403|UniProtKB=A0ACM8ELQ5 A0ACM8ELQ5 LOC120839403 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC121836622|UniProtKB=A0ACM8FYX5 A0ACM8FYX5 LOC121836622 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115330956|UniProtKB=A0ACM8ES43 A0ACM8ES43 LOC115330956 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115329254|UniProtKB=A0ACM8FB80 A0ACM8FB80 LOC115329254 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8023658|UniProtKB=A0ACM8DV07 A0ACM8DV07 Cdc10 PTHR24056:SF508 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 10 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of cell cycle G2/M phase transition#GO:1902749;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;mitotic cell cycle phase transition#GO:0044772 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8053058|UniProtKB=A0ACM8DP82 A0ACM8DP82 Stat92E PTHR11801:SF70 SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION SIGNAL TRANSDUCER AND TRANSCRIPTION ACTIVATOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;cell surface receptor signaling pathway via STAT#GO:0097696;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell surface receptor signaling pathway via JAK-STAT#GO:0007259;cell surface receptor signaling pathway#GO:0007166;defense response#GO:0006952;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 EGF receptor signaling pathway#P00018>STAT#P00561;PDGF signaling pathway#P00047>STAT#P01173 IXOSC|EnsemblGenome=LOC121046138|UniProtKB=A0ACM8G6I7 A0ACM8G6I7 LOC121046138 PTHR24172:SF4 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANK_REP_REGION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036969|UniProtKB=A0ACM8ESE0 A0ACM8ESE0 LOC8036969 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840924|UniProtKB=A0ACM8EQM5 A0ACM8EQM5 LOC120840924 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115319496|UniProtKB=A0ACM8DZD2 A0ACM8DZD2 LOC115319496 PTHR34921:SF1 MEIOTIC RECOMBINATION PROTEIN REC114 MEIOTIC RECOMBINATION PROTEIN REC114 IXOSC|EnsemblGenome=LOC120839843|UniProtKB=A0ACM8EN76 A0ACM8EN76 LOC120839843 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121834861|UniProtKB=A0ACM8FRH8 A0ACM8FRH8 LOC121834861 PTHR43313:SF65 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C SHORT-CHAIN DEHYDROGENASE_REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8023151|UniProtKB=A0ACM8E762 A0ACM8E762 Ucp4A PTHR45618:SF8 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL UNCOUPLING PROTEIN 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 response to stimulus#GO:0050896;response to cold#GO:0009409;response to temperature stimulus#GO:0009266;response to abiotic stimulus#GO:0009628;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8050916|UniProtKB=A0ACM8G7V6 A0ACM8G7V6 LOC8050916 PTHR23354:SF122 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED GTPASE-ACTIVATING PROTEIN SKYWALKER IXOSC|EnsemblGenome=LOC115311733|UniProtKB=A0ACM8DR44 A0ACM8DR44 LOC115311733 PTHR21230:SF89 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B SNAP receptor activity#GO:0005484;protein binding#GO:0005515;binding#GO:0005488;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674 establishment of localization#GO:0051234;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;macroautophagy#GO:0016236;membrane organization#GO:0061024;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;catabolic process#GO:0009056;vesicle fusion#GO:0006906;intra-Golgi vesicle-mediated transport#GO:0006891;Golgi organization#GO:0007030;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosomal transport#GO:0016197;metabolic process#GO:0008152;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;post-Golgi vesicle-mediated transport#GO:0006892;cytosolic transport#GO:0016482;cellular component organization#GO:0016043 bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;endoplasmic reticulum#GO:0005783;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;ER to Golgi transport vesicle membrane#GO:0012507;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982 membrane traffic protein#PC00150;SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 IXOSC|EnsemblGenome=LOC120846512|UniProtKB=A0ACM8FH65 A0ACM8FH65 LOC120846512 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8027946|UniProtKB=A0ACM8EAU7 A0ACM8EAU7 LOC8027946 PTHR22969:SF17 IKB KINASE INHIBITOR OF NUCLEAR FACTOR KAPPA-B KINASE SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>IKK#P00313 IXOSC|EnsemblGenome=LOC120840405|UniProtKB=A0ACM8ENH8 A0ACM8ENH8 LOC120840405 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120838135|UniProtKB=A0ACM8EK26 A0ACM8EK26 LOC120838135 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041411|UniProtKB=A0ACM8DKP3 A0ACM8DKP3 LOC8041411 PTHR47217:SF1 GLOBIN-LIKE PROTEIN GLOBIN-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120843928|UniProtKB=A0ACM8EX64 A0ACM8EX64 LOC120843928 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030981|UniProtKB=A0ACM8F631 A0ACM8F631 LOC8030981 PTHR11267:SF181 T-BOX PROTEIN-RELATED OPTOMOTOR-BLIND PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 IXOSC|EnsemblGenome=LOC8037780|UniProtKB=A0ACM8ED78 A0ACM8ED78 LOC8037780 PTHR13256:SF16 N-ACETYLTRANSFERASE 9 ALPHA_BETA-TUBULIN-N-ACETYLTRANSFERASE 9 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;regulation of microtubule-based process#GO:0032886;regulation of microtubule polymerization#GO:0031113;positive regulation of organelle organization#GO:0010638;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;positive regulation of protein polymerization#GO:0032273;positive regulation of cellular component biogenesis#GO:0044089;regulation of microtubule polymerization or depolymerization#GO:0031110 IXOSC|EnsemblGenome=LOC115316529|UniProtKB=A0ACM8FTU5 A0ACM8FTU5 LOC115316529 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120836303|UniProtKB=A0ACM8EKW6 A0ACM8EKW6 LOC120836303 PTHR11946:SF93 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC115311501|UniProtKB=A0ACM8ERH4 A0ACM8ERH4 LOC115311501 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 reductase#PC00198 IXOSC|EnsemblGenome=LOC8033987|UniProtKB=A0ACM8DN98 A0ACM8DN98 LOC8033987 PTHR43814:SF1 ARGININOSUCCINATE LYASE ARGININOSUCCINATE LYASE catalytic activity#GO:0003824;lyase activity#GO:0016829 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;L-arginine biosynthetic process#GO:0006526;proteinogenic amino acid biosynthetic process#GO:0170038 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144 Arginine biosynthesis#P02728>argininosuccinate lyase#P02841 IXOSC|EnsemblGenome=LOC8042353|UniProtKB=A0ACM8EPM9 A0ACM8EPM9 LOC8042353 PTHR45928:SF1 RE38146P RE38146P IXOSC|EnsemblGenome=LOC8031046|UniProtKB=A0ACM8EU34 A0ACM8EU34 LOC8031046 PTHR24055:SF616 MITOGEN-ACTIVATED PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 organelle assembly#GO:0070925;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;cellular response to stimulus#GO:0051716;intraciliary transport#GO:0042073;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;signaling#GO:0023052;cell projection organization#GO:0030030;response to stimulus#GO:0050896;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;signal transduction#GO:0007165;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115311254|UniProtKB=A0ACM8DQS2 A0ACM8DQS2 LOC115311254 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8051641|UniProtKB=A0ACM8DLD5 A0ACM8DLD5 PTHR22884:SF498 SET DOMAIN PROTEINS NUCLEAR RECEPTOR BINDING SET DOMAIN PROTEIN catalytic activity, acting on a protein#GO:0140096;histone H3K36 methyltransferase activity#GO:0046975;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120837746|UniProtKB=A0ACM8EJ56 A0ACM8EJ56 LOC120837746 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037389|UniProtKB=A0ACM8ERB9 A0ACM8ERB9 LOC8037389 PTHR47969:SF41 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED KINESIN-LIKE PROTEIN KIF21A ISOFORM X1 isomerase activity#GO:0016853;microtubule motor activity#GO:0003777;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544 mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;organelle organization#GO:0006996;cellular process#GO:0009987;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC8035130|UniProtKB=A0ACM8DJR1 A0ACM8DJR1 LOC8035130 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC121836340|UniProtKB=A0ACM8FZC2 A0ACM8FZC2 LOC121836340 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8026784|UniProtKB=A0ACM8DXE6 A0ACM8DXE6 LOC8026784 PTHR47958:SF215 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC120843843|UniProtKB=A0ACM8EWQ7 A0ACM8EWQ7 LOC120843843 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8040763|UniProtKB=A0ACM8DH24 A0ACM8DH24 LOC8040763 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 IXOSC|EnsemblGenome=LOC8053386|UniProtKB=A0ACM8DU65 A0ACM8DU65 bbc PTHR10414:SF78 ETHANOLAMINEPHOSPHOTRANSFERASE DIACYLGLYCEROL CHOLINEPHOSPHOTRANSFERASE transferase#PC00220 IXOSC|EnsemblGenome=LOC115328992|UniProtKB=A0ACM8EAB9 A0ACM8EAB9 LOC115328992 PTHR48112:SF31 HIGH MOBILITY GROUP PROTEIN DSP1 HMG BOX DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC121835721|UniProtKB=A0ACM8FUU7 A0ACM8FUU7 LOC121835721 PTHR47501:SF10 TRANSPOSASE-RELATED DUF659 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8025467|UniProtKB=A0ACM8G184 A0ACM8G184 Nup214 PTHR23193:SF46 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP214 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC120837336|UniProtKB=A0ACM8FQR5 A0ACM8FQR5 LOC120837336 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120836706|UniProtKB=A0ACM8EFN4 A0ACM8EFN4 LOC120836706 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC120848984|UniProtKB=A0ACM8F731 A0ACM8F731 LOC120848984 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8035309|UniProtKB=A0ACM8DWP9 A0ACM8DWP9 Coq8 PTHR43851:SF3 FAMILY NOT NAMED COENZYME Q8 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ketone metabolic process#GO:0042180;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 IXOSC|EnsemblGenome=LOC115320941|UniProtKB=A0ACM8ES85 A0ACM8ES85 LOC115320941 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321088|UniProtKB=A0ACM8EH18 A0ACM8EH18 LOC115321088 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC8023498|UniProtKB=A0ACM8DXM4 A0ACM8DXM4 LOC8023498 PTHR11506:SF35 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 5 establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of protein localization#GO:0045184 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8035855|UniProtKB=A0ACM8DWZ9 A0ACM8DWZ9 PTHR31671:SF3 DIABETES AND OBESITY REGULATED, ISOFORM G DIABETES AND OBESITY REGULATED, ISOFORM G protein-membrane adaptor activity#GO:0043495;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;protein-macromolecule adaptor activity#GO:0030674;transcription coregulator activity#GO:0003712;molecular adaptor activity#GO:0060090 metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;process utilizing autophagic mechanism#GO:0061919;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macroautophagy#GO:0016236;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;organelle assembly#GO:0070925;regulation of RNA metabolic process#GO:0051252;vacuole organization#GO:0007033;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC121833826|UniProtKB=A0ACM8FP65 A0ACM8FP65 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8032204|UniProtKB=A0ACM8DVR6 A0ACM8DVR6 PIG-L PTHR12993:SF11 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deacetylase activity#GO:0019213;hydrolase activity#GO:0016787;deacylase activity#GO:0160215;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 deacetylase#PC00087 IXOSC|EnsemblGenome=LOC121835670|UniProtKB=A0ACM8FUN9 A0ACM8FUN9 LOC121835670 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8035064|UniProtKB=A0ACM8EDA3 A0ACM8EDA3 LOC8035064 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8039247|UniProtKB=A0ACM8DRV2 A0ACM8DRV2 LOC8039247 PTHR11934:SF0 RIBOSE-5-PHOSPHATE ISOMERASE RIBOSE-5-PHOSPHATE ISOMERASE isomerase activity#GO:0016853;ribose-5-phosphate isomerase activity#GO:0004751;intramolecular oxidoreductase activity#GO:0016860;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nucleobase-containing compound metabolic process#GO:0006139;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;glucose 6-phosphate metabolic process#GO:0051156;small molecule metabolic process#GO:0044281;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;NADPH regeneration#GO:0006740;pentose-phosphate shunt#GO:0006098;nucleotide metabolic process#GO:0009117 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Pentose phosphate pathway#P02762>Ribulose 5-P Isomerase#P03071 IXOSC|EnsemblGenome=LOC115313401|UniProtKB=A0ACM8DSS0 A0ACM8DSS0 LOC115313401 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052229|UniProtKB=A0ACM8DM39 A0ACM8DM39 LOC8052229 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8024394|UniProtKB=A0ACM8DWT1 A0ACM8DWT1 LOC8024394 PTHR11783:SF341 SULFOTRANSFERASE SULT SULFOTRANSFER_1 DOMAIN-CONTAINING PROTEIN sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8024693|UniProtKB=A0ACM8DY51 A0ACM8DY51 LOC8024693 PTHR21771:SF1 MITOCHONDRIA-EATING PROTEIN-RELATED MITOCHONDRIA-EATING PROTEIN IXOSC|EnsemblGenome=LOC8033302|UniProtKB=A0ACM8DHN8 A0ACM8DHN8 LOC8033302 PTHR14149:SF14 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;cytoskeletal protein binding#GO:0008092;calmodulin binding#GO:0005516;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;mitotic cell cycle process#GO:1903047;actomyosin contractile ring assembly#GO:0000915;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;actin filament-based process#GO:0030029;cytokinetic process#GO:0032506;mitotic cytokinetic process#GO:1902410;cortical actin cytoskeleton organization#GO:0030866;cytoskeleton-dependent cytokinesis#GO:0061640;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;actomyosin structure organization#GO:0031032 cell periphery#GO:0071944;cell cortex#GO:0005938;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC121835365|UniProtKB=A0ACM8FTL1 A0ACM8FTL1 LOC121835365 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120847361|UniProtKB=A0ACM8F320 A0ACM8F320 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8053449|UniProtKB=A0ACM8DUI8 A0ACM8DUI8 PTHR24396:SF19 ZINC FINGER PROTEIN FI01119P cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115312896|UniProtKB=A0ACM8DSA2 A0ACM8DSA2 LOC115312896 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053025|UniProtKB=A0ACM8DQZ5 A0ACM8DQZ5 LOC8053025 PTHR10366:SF853 NAD DEPENDENT EPIMERASE/DEHYDRATASE GH25466P oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 lyase#PC00144;dehydratase#PC00091;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8051863|UniProtKB=A0ACM8ED40 A0ACM8ED40 LOC8051863 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8033764|UniProtKB=A0ACM8DIB3 A0ACM8DIB3 Hinfp PTHR24391:SF30 HISTONE H4 TRANSCRIPTION FACTOR-RELATED EG:115C2.6 PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8041700|UniProtKB=A0ACM8DKS7 A0ACM8DKS7 LOC8041700 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8052914|UniProtKB=A0ACM8FCL8 A0ACM8FCL8 LOC8052914 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120848699|UniProtKB=A0ACM8F6K0 A0ACM8F6K0 LOC120848699 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835734|UniProtKB=A0ACM8FWB8 A0ACM8FWB8 LOC121835734 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121837018|UniProtKB=A0ACM8G256 A0ACM8G256 LOC121837018 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8051996|UniProtKB=A0ACM8E6L3 A0ACM8E6L3 LOC8051996 PTHR14463:SF10 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 1 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 IXOSC|EnsemblGenome=LOC8043600|UniProtKB=A0ACM8EA16 A0ACM8EA16 Argk1 PTHR11547:SF38 ARGININE OR CREATINE KINASE ARGININE KINASE 1-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;amino acid kinase#PC00045 IXOSC|EnsemblGenome=LOC8029150|UniProtKB=A0ACM8ETM2 A0ACM8ETM2 LOC8029150 PTHR23280:SF4 4.1 G PROTEIN BAND 4.1-LIKE PROTEIN 4A cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8051012|UniProtKB=A0ACM8FU59 A0ACM8FU59 LOC8051012 PTHR15012:SF40 APICAL PROTEIN/SHROOM-RELATED PROTEIN SHROOM3-LIKE ISOFORM X1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical cytoskeleton#GO:0030863;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;intracellular organelle#GO:0043229;plasma membrane region#GO:0098590;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical junction complex#GO:0043296;apical part of cell#GO:0045177 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC121835126|UniProtKB=A0ACM8FSG2 A0ACM8FSG2 LOC121835126 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8050776|UniProtKB=A0ACM8DLU3 A0ACM8DLU3 LOC8050776 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8036256|UniProtKB=A0ACM8DHB6 A0ACM8DHB6 LOC8036256 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8052772|UniProtKB=A0ACM8DQN5 A0ACM8DQN5 PTHR12064:SF94 METAL TRANSPORTER CNNM UNEXTENDED PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8029342|UniProtKB=A0ACM8DYE0 A0ACM8DYE0 LOC8029342 PTHR11530:SF17 D-AMINO ACID OXIDASE RE49860P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 oxidase#PC00175 IXOSC|EnsemblGenome=LOC120843402|UniProtKB=A0ACM8G5S4 A0ACM8G5S4 LOC120843402 PTHR45620:SF15 PDF RECEPTOR-LIKE PROTEIN-RELATED DIURETIC HORMONE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;hormone binding#GO:0042562 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8027394|UniProtKB=A0ACM8DUF2 A0ACM8DUF2 LOC8027394 PTHR19269:SF45 TROPOMYOSIN TROPOMYOSIN-1, ISOFORMS 33_34 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 multicellular organismal process#GO:0032501;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;muscle system process#GO:0003012;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;muscle contraction#GO:0006936;actin filament-based process#GO:0030029 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232 actin binding motor protein#PC00040 IXOSC|EnsemblGenome=LOC8027576|UniProtKB=A0ACM8F9M9 A0ACM8F9M9 LOC8027576 PTHR11566:SF237 DYNAMIN DYNAMIN GTPASE ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;tubulin binding#GO:0015631;hydrolase activity#GO:0016787;protein binding#GO:0005515;microtubule binding#GO:0008017;GTPase activity#GO:0003924;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 peroxisome organization#GO:0007031;organelle localization#GO:0051640;mitochondrion localization#GO:0051646;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115316105|UniProtKB=A0ACM8DVZ5 A0ACM8DVZ5 Idi PTHR10885:SF24 ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE ISOPENTENYL-DIPHOSPHATE DELTA-ISOMERASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 isomerase#PC00135 IXOSC|EnsemblGenome=LOC120839695|UniProtKB=A0ACM8ENH7 A0ACM8ENH7 LOC120839695 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027958|UniProtKB=A0ACM8DXD1 A0ACM8DXD1 LOC8027958 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8029743|UniProtKB=A0ACM8E516 A0ACM8E516 LOC8029743 PTHR16064:SF3 BTB POZ DOMAIN CONTAINING 7 BTB_POZ DOMAIN-CONTAINING PROTEIN 7 IXOSC|EnsemblGenome=LOC120837748|UniProtKB=A0ACM8EHP7 A0ACM8EHP7 LOC120837748 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036697|UniProtKB=A0ACM8EX12 A0ACM8EX12 LOC8036697 PTHR16231:SF4 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 4 IXOSC|EnsemblGenome=LOC115327436|UniProtKB=A0ACM8E812 A0ACM8E812 LOC115327436 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120840601|UniProtKB=A0ACM8EPK6 A0ACM8EPK6 LOC120840601 PTHR24251:SF57 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120847664|UniProtKB=A0ACM8F4B5 A0ACM8F4B5 LOC120847664 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8042230|UniProtKB=A0ACM8EG24 A0ACM8EG24 l(2)37Cd PTHR13230:SF5 GENERAL TRANSCRIPTION FACTOR IIIC, POLYPEPTIDE 5 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 5 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;rRNA transcription#GO:0009303;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 transcription factor TFIIIC complex#GO:0000127;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8025122|UniProtKB=A0ACM8DUV0 A0ACM8DUV0 LOC8025122 PTHR31353:SF1 FAM98 PROTEIN FAM98B catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC121834190|UniProtKB=A0ACM8FQD3 A0ACM8FQD3 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322641|UniProtKB=A0ACM8E355 A0ACM8E355 LOC115322641 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8051023|UniProtKB=A0ACM8DLH0 A0ACM8DLH0 LOC8051023 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP synthase#PC00002;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8032342|UniProtKB=A0ACM8E3M3 A0ACM8E3M3 hyx PTHR12466:SF8 CDC73 DOMAIN PROTEIN PARAFIBROMIN protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899 positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 IXOSC|EnsemblGenome=LOC8050673|UniProtKB=A0ACM8ECU1 A0ACM8ECU1 Nbr PTHR47765:SF2 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN EXONUCLEASE MUT-7 HOMOLOG IXOSC|EnsemblGenome=LOC8032474|UniProtKB=A0ACM8EA71 A0ACM8EA71 G9a PTHR46307:SF5 G9A, ISOFORM B G9A, ISOFORM B membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120837905|UniProtKB=A0ACM8EJB0 A0ACM8EJB0 LOC120837905 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8043631|UniProtKB=A0ACM8FG73 A0ACM8FG73 LOC8043631 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC8032759|UniProtKB=A0ACM8E4Y3 A0ACM8E4Y3 LOC8032759 PTHR11675:SF43 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8051070|UniProtKB=A0ACM8FA64 A0ACM8FA64 DCTN4-p62 PTHR13034:SF2 DYNACTIN P62 SUBUNIT DYNACTIN SUBUNIT 4 establishment of localization in cell#GO:0051649;transport#GO:0006810;cellular process#GO:0009987;intracellular transport#GO:0046907;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC121838461|UniProtKB=A0ACM8G8C1 A0ACM8G8C1 LOC121838461 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115318980|UniProtKB=A0ACM8EGB0 A0ACM8EGB0 LOC115318980 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115324205|UniProtKB=A0ACM8EPW2 A0ACM8EPW2 LOC115324205 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8040525|UniProtKB=A0ACM8EB76 A0ACM8EB76 LOC8040525 PTHR46485:SF5 LIM DOMAIN KINASE 1 DUAL-SPECIFICITY KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121833948|UniProtKB=A0ACM8FPM7 A0ACM8FPM7 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8039176|UniProtKB=A0ACM8E366 A0ACM8E366 LOC8039176 PTHR21646:SF24 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 19 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8024611|UniProtKB=A0ACM8E1A9 A0ACM8E1A9 LOC8024611 PTHR46555:SF1 UBIQUITIN-LIKE PROTEIN 4A UBIQUITIN-LIKE PROTEIN 4A IXOSC|EnsemblGenome=LOC8030724|UniProtKB=A0ACM8DHG0 A0ACM8DHG0 LOC8030724 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC120847426|UniProtKB=A0ACM8F455 A0ACM8F455 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326524|UniProtKB=A0ACM8E6S9 A0ACM8E6S9 LOC115326524 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8041597|UniProtKB=A0ACM8EC32 A0ACM8EC32 Ufsp1 PTHR48153:SF3 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 1 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8034354|UniProtKB=A0ACM8DPL1 A0ACM8DPL1 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8030166|UniProtKB=A0ACM8FU45 A0ACM8FU45 LOC8030166 PTHR11647:SF1 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;dihydropyrimidinase activity#GO:0004157 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 IXOSC|EnsemblGenome=LOC120849894|UniProtKB=A0ACM8F8Q0 A0ACM8F8Q0 LOC120849894 PTHR28641:SF1 FAMILY NOT NAMED MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL IXOSC|EnsemblGenome=LOC8035698|UniProtKB=A0ACM8FE75 A0ACM8FE75 LOC8035698 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC120844354|UniProtKB=A0ACM8EYJ9 A0ACM8EYJ9 LOC120844354 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115333214|UniProtKB=A0ACM8EEP6 A0ACM8EEP6 LOC115333214 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8028009|UniProtKB=A0ACM8EXU6 A0ACM8EXU6 LOC8028009 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular process#GO:0009987;cellular response to stimulus#GO:0051716;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887 membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121834533|UniProtKB=A0ACM8FQ91 A0ACM8FQ91 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8033693|UniProtKB=A0ACM8E228 A0ACM8E228 LOC8033693 PTHR14580:SF0 MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 FAMILY MEMBER MULTIPLE MYELOMA TUMOR-ASSOCIATED PROTEIN 2 IXOSC|EnsemblGenome=LOC8038212|UniProtKB=A0ACM8DGP6 A0ACM8DGP6 LOC8038212 PTHR24289:SF24 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 21-HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;hormone metabolic process#GO:0042445;steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;biological regulation#GO:0065007;metabolic process#GO:0008152;olefinic compound metabolic process#GO:0120254;lipid metabolic process#GO:0006629;regulation of biological quality#GO:0065008 IXOSC|EnsemblGenome=LOC8023100|UniProtKB=A0ACM8EBU2 A0ACM8EBU2 LOC8023100 PTHR10363:SF2 BLEOMYCIN HYDROLASE BLEOMYCIN HYDROLASE aminopeptidase activity#GO:0004177;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;response to chemical#GO:0042221;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;sulfur compound metabolic process#GO:0006790;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8053980|UniProtKB=A0ACM8EED8 A0ACM8EED8 LOC8053980 PTHR18034:SF4 CELL CYCLE CONTROL PROTEIN CWF22-RELATED NUCLEOLAR MIF4G DOMAIN-CONTAINING PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8023675|UniProtKB=A0ACM8DHD8 A0ACM8DHD8 LOC8023675 PTHR31200:SF1 INO80 COMPLEX SUBUNIT C INO80 COMPLEX SUBUNIT C cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840 chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011 IXOSC|EnsemblGenome=LOC115320136|UniProtKB=A0ACM8E0Z0 A0ACM8E0Z0 PTHR23359:SF111 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 5 phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 nucleotide kinase#PC00172;kinase#PC00137 IXOSC|EnsemblGenome=LOC8033188|UniProtKB=A0ACM8E6S5 A0ACM8E6S5 LOC8033188 PTHR46497:SF1 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 11 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8038216|UniProtKB=A0ACM8EUQ9 A0ACM8EUQ9 LOC8038216 PTHR24289:SF24 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 21-HYDROXYLASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;hormone biosynthetic process#GO:0042446;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;regulation of biological quality#GO:0065008;metabolic process#GO:0008152;olefinic compound metabolic process#GO:0120254;lipid metabolic process#GO:0006629 IXOSC|EnsemblGenome=LOC8032113|UniProtKB=A0ACM8FXD8 A0ACM8FXD8 Plod PTHR10730:SF45 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cellular process#GO:0009987;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;collagen fibril organization#GO:0030199;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8024438|UniProtKB=A0ACM8DW38 A0ACM8DW38 LOC8024438 PTHR10003:SF86 SUPEROXIDE DISMUTASE CU-ZN -RELATED COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;molecular carrier activity#GO:0140104;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;catalytic activity#GO:0003824;copper ion binding#GO:0005507;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491 cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to stress#GO:0006950;cellular process#GO:0009987;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;response to reactive oxygen species#GO:0000302;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8041447|UniProtKB=A0ACM8EXC2 A0ACM8EXC2 LOC8041447 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC115326788|UniProtKB=A0ACM8F7M3 A0ACM8F7M3 LOC115326788 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 IXOSC|EnsemblGenome=LOC120843669|UniProtKB=A0ACM8EWN0 A0ACM8EWN0 LOC120843669 PTHR11530:SF11 D-AMINO ACID OXIDASE D-AMINO ACID OXIDASE 2, ISOFORM A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 IXOSC|EnsemblGenome=LOC115327774|UniProtKB=A0ACM8FA53 A0ACM8FA53 LOC115327774 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041412|UniProtKB=A0ACM8DR66 A0ACM8DR66 LOC8041412 PTHR47901:SF10 CASPASE RECRUITMENT DOMAIN-CONTAINING PROTEIN 18 PEPTIDASE C14A CASPASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029988|UniProtKB=A0ACM8DJ54 A0ACM8DJ54 LOC8029988 PTHR21386:SF0 INSCUTEABLE PROTEIN INSCUTEABLE HOMOLOG cytoskeletal adaptor activity#GO:0008093;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular protein localization#GO:0008104;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell division#GO:0051302;macromolecule localization#GO:0033036 cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120838932|UniProtKB=A0ACM8EL33 A0ACM8EL33 LOC120838932 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8043879|UniProtKB=A0ACM8FS51 A0ACM8FS51 LOC8043879 PTHR22255:SF10 LP06548P ARGUS, ISOFORM A organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;organelle organization#GO:0006996;membrane fusion#GO:0061025;autophagy#GO:0006914;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;metabolic process#GO:0008152;transport#GO:0006810;catabolic process#GO:0009056;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919 IXOSC|EnsemblGenome=LOC8034613|UniProtKB=A0ACM8FZ03 A0ACM8FZ03 Cap-D2 PTHR14222:SF2 CONDENSIN CONDENSIN COMPLEX SUBUNIT 1 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;cell cycle#GO:0007049;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;organelle fission#GO:0048285;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;nuclear division#GO:0000280;sexual reproduction#GO:0019953;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome segregation#GO:0007059 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;condensin complex#GO:0000796;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115333187|UniProtKB=A0ACM8EPQ2 A0ACM8EPQ2 LOC115333187 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120836857|UniProtKB=A0ACM8EGX9 A0ACM8EGX9 LOC120836857 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8038570|UniProtKB=A0ACM8E2S0 A0ACM8E2S0 Arpc3A PTHR12391:SF0 ARP2/3 COMPLEX 21 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 3 cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Integrin signalling pathway#P00034>Arp2/3#P00912;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 IXOSC|EnsemblGenome=LOC120842436|UniProtKB=A0ACM8FVM4 A0ACM8FVM4 LOC120842436 PTHR24264:SF91 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115321957|UniProtKB=A0ACM8F0W4 A0ACM8F0W4 PTHR47969:SF41 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED KINESIN-LIKE PROTEIN KIF21A ISOFORM X1 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC8040702|UniProtKB=A0ACM8DMG2 A0ACM8DMG2 LOC8040702 PTHR24166:SF55 ROLLING PEBBLES, ISOFORM B ROLLING PEBBLES, ISOFORM B scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8042798|UniProtKB=A0ACM8E3B3 A0ACM8E3B3 Nup98-96 PTHR23198:SF6 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96 nucleic acid binding#GO:0003676;binding#GO:0005488;structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056;RNA binding#GO:0003723 cellular component organization#GO:0016043;cellular localization#GO:0051641;protein import into nucleus#GO:0006606;protein transport#GO:0015031;telomere tethering at nuclear periphery#GO:0034398;chromosome localization#GO:0050000;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;telomere localization#GO:0034397;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 transporter#PC00227 IXOSC|EnsemblGenome=LOC8025954|UniProtKB=A0ACM8G8L3 A0ACM8G8L3 LOC8025954 PTHR19423:SF1 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;kinase inhibitor activity#GO:0019210;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120844899|UniProtKB=A0ACM8EZW0 A0ACM8EZW0 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8040604|UniProtKB=A0ACM8DKJ4 A0ACM8DKJ4 LOC8040604 PTHR11177:SF144 CHITINASE CHITINASE chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115311762|UniProtKB=A0ACM8DRG5 A0ACM8DRG5 LOC115311762 PTHR12271:SF66 POLY A POLYMERASE CID PAP -RELATED GH05885P catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;modification-dependent macromolecule catabolic process#GO:0043632;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC120846018|UniProtKB=A0ACM8F1B0 A0ACM8F1B0 LOC120846018 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030956|UniProtKB=A0ACM8E017 A0ACM8E017 PTHR12942:SF2 STEP II SPLICING FACTOR SLU7 PRE-MRNA-SPLICING FACTOR SLU7 RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;binding#GO:0005488 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8023472|UniProtKB=A0ACM8E1C7 A0ACM8E1C7 LOC8023472 PTHR22891:SF198 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-1 catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;single-stranded RNA binding#GO:0003727;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120842393|UniProtKB=A0ACM8ETQ6 A0ACM8ETQ6 LOC120842393 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040204|UniProtKB=A0ACM8F7A6 A0ACM8F7A6 LOC8040204 PTHR11690:SF305 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC120837912|UniProtKB=A0ACM8EJK8 A0ACM8EJK8 LOC120837912 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844002|UniProtKB=A0ACM8EX67 A0ACM8EX67 LOC120844002 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037183|UniProtKB=A0ACM8E4B7 A0ACM8E4B7 LOC8037183 PTHR48418:SF1 TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3 TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 3 IXOSC|EnsemblGenome=LOC115325933|UniProtKB=A0ACM8FP20 A0ACM8FP20 LOC115325933 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115310371|UniProtKB=A0ACM8FAV3 A0ACM8FAV3 LOC115310371 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121833694|UniProtKB=A0ACM8FKZ7 A0ACM8FKZ7 LOC121833694 PTHR47160:SF13 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027462|UniProtKB=A0ACM8EFT7 A0ACM8EFT7 LOC8027462 PTHR45656:SF17 PROTEIN CBR-CLEC-78 SUSHI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050880|UniProtKB=A0ACM8E644 A0ACM8E644 LOC8050880 PTHR18901:SF48 2-DEOXYGLUCOSE-6-PHOSPHATE PHOSPHATASE 2 PSEUDOURIDINE-5'-PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115319234|UniProtKB=A0ACM8DYY0 A0ACM8DYY0 LOC115319234 PTHR21357:SF4 FAM172 FAMILY PROTEIN HOMOLOG CG10038 FAM172 FAMILY PROTEIN HOMOLOG CG10038 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120836604|UniProtKB=A0ACM8EFH2 A0ACM8EFH2 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838328|UniProtKB=A0ACM8G8T7 A0ACM8G8T7 LOC121838328 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8026292|UniProtKB=A0ACM8DWV8 A0ACM8DWV8 Nup154 PTHR10350:SF6 NUCLEAR PORE COMPLEX PROTEIN NUP155 NUCLEAR PORE COMPLEX PROTEIN NUP155 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;localization within membrane#GO:0051668;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transporter#PC00227 IXOSC|EnsemblGenome=LOC8036943|UniProtKB=A0ACM8DK16 A0ACM8DK16 LOC8036943 PTHR10543:SF152 BETA-CAROTENE DIOXYGENASE CAROTENOID ISOMEROOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;olefinic compound metabolic process#GO:0120254;diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;isoprenoid metabolic process#GO:0006720;lipid catabolic process#GO:0016042;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;primary metabolic process#GO:0044238;catabolic process#GO:0009056 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120839552|UniProtKB=A0ACM8EM90 A0ACM8EM90 LOC120839552 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120843847|UniProtKB=A0ACM8FX28 A0ACM8FX28 LOC120843847 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8039177|UniProtKB=A0ACM8E2V6 A0ACM8E2V6 LOC8039177 PTHR13480:SF0 E3 UBIQUITIN-PROTEIN LIGASE HAKAI-RELATED E3 UBIQUITIN-PROTEIN LIGASE HAKAI catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;regulation of cell adhesion#GO:0030155;regulation of cellular process#GO:0050794;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115313678|UniProtKB=A0ACM8EHE7 A0ACM8EHE7 LOC115313678 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8041402|UniProtKB=A0ACM8EET3 A0ACM8EET3 PTHR21538:SF23 ANILLIN/RHOTEKIN RTKN ANILLIN mitotic cell cycle#GO:0000278;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;actomyosin structure organization#GO:0031032;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell division#GO:0051301;cell cycle process#GO:0022402;cytoskeleton-dependent cytokinesis#GO:0061640;septin ring organization#GO:0031106;cortical actin cytoskeleton organization#GO:0030866;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actomyosin contractile ring assembly#GO:0000915;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;septin cytoskeleton organization#GO:0032185 cell periphery#GO:0071944;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;actomyosin contractile ring#GO:0005826;contractile ring#GO:0070938;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC120844100|UniProtKB=A0ACM8EXK0 A0ACM8EXK0 LOC120844100 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8036335|UniProtKB=A0ACM8E2X6 A0ACM8E2X6 LOC8036335 PTHR13060:SF0 SGT1 PROTEIN HSGT1 SUPPRESSOR OF GCR2 PROTEIN ECDYSONELESS HOMOLOG transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8025848|UniProtKB=A0ACM8G4S7 A0ACM8G4S7 LOC8025848 PTHR11255:SF109 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE ETA lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;biological regulation#GO:0065007;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;neutral lipid metabolic process#GO:0006638;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 kinase#PC00137;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8026665|UniProtKB=A0ACM8F5M5 A0ACM8F5M5 LOC8026665 PTHR13563:SF19 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG B nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;tRNA binding#GO:0000049 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC120843793|UniProtKB=A0ACM8EWV9 A0ACM8EWV9 LOC120843793 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332822|UniProtKB=A0ACM8F9Z6 A0ACM8F9Z6 LOC115332822 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8032849|UniProtKB=A0ACM8FQ76 A0ACM8FQ76 PTHR11412:SF166 MACROGLOBULIN / COMPLEMENT OPHIOPHAGUS VENOM FACTOR-LIKE signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8053757|UniProtKB=A0ACM8ECC9 A0ACM8ECC9 Not3 PTHR23326:SF1 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 positive regulation of macromolecule metabolic process#GO:0010604;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;CCR4-NOT complex#GO:0030014;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115319357|UniProtKB=A0ACM8DZM7 A0ACM8DZM7 LOC115319357 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120841042|UniProtKB=A0ACM8ERU0 A0ACM8ERU0 LOC120841042 PTHR46481:SF16 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 BED-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042416|UniProtKB=A0ACM8DKW8 A0ACM8DKW8 LOC8042416 PTHR11893:SF41 INNEXIN INNEXIN INX2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 cell communication#GO:0007154;response to external stimulus#GO:0009605;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;cellular response to stimulus#GO:0051716;response to radiation#GO:0009314;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 gap junction#PC00105 IXOSC|EnsemblGenome=LOC120844137|UniProtKB=A0ACM8EXX9 A0ACM8EXX9 LOC120844137 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152 intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121834276|UniProtKB=A0ACM8FPP6 A0ACM8FPP6 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841708|UniProtKB=A0ACM8ETA9 A0ACM8ETA9 LOC120841708 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115320121|UniProtKB=A0ACM8FVW1 A0ACM8FVW1 LOC115320121 PTHR23235:SF191 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 384 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8035081|UniProtKB=A0ACM8E8C0 A0ACM8E8C0 LOC8035081 PTHR46228:SF2 KELCH DOMAIN-CONTAINING PROTEIN KELCH REPEAT PROTEIN (AFU_ORTHOLOGUE AFUA_4G14350) IXOSC|EnsemblGenome=LOC120848772|UniProtKB=A0ACM8F6Q2 A0ACM8F6Q2 LOC120848772 PTHR15876:SF8 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 TRANSMEMBRANE PROTEIN ADIPOCYTE-ASSOCIATED 1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8028440|UniProtKB=A0ACM8E0L6 A0ACM8E0L6 LOC8028440 PTHR15276:SF0 H4 D10S170 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 6 IXOSC|EnsemblGenome=LOC121045949|UniProtKB=A0ACM8FCS1 A0ACM8FCS1 LOC121045949 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040312|UniProtKB=A0ACM8ERS9 A0ACM8ERS9 LOC8040312 PTHR10454:SF253 CASPASE CASPASE DRICE-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;programmed cell death#GO:0012501;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8024902|UniProtKB=A0ACM8DRH6 A0ACM8DRH6 IntS9 PTHR46094:SF1 INTEGRATOR COMPLEX SUBUNIT 9 INTEGRATOR COMPLEX SUBUNIT 9 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039 IXOSC|EnsemblGenome=LOC8036712|UniProtKB=A0ACM8EC84 A0ACM8EC84 LOC8036712 PTHR46424:SF1 UBX DOMAIN-CONTAINING PROTEIN 4 UBX DOMAIN-CONTAINING PROTEIN 4 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8039062|UniProtKB=A0ACM8EEJ2 A0ACM8EEJ2 LOC8039062 PTHR44307:SF2 PHOSPHOETHANOLAMINE METHYLTRANSFERASE PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;phosphatidylcholine biosynthetic process#GO:0006656;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120841165|UniProtKB=A0ACM8EQQ3 A0ACM8EQQ3 LOC120841165 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052180|UniProtKB=A0ACM8DLG8 A0ACM8DLG8 LOC8052180 PTHR46749:SF1 COMPLEX III ASSEMBLY FACTOR LYRM7 COMPLEX III ASSEMBLY FACTOR LYRM7 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121046842|UniProtKB=A0ACM8FF11 A0ACM8FF11 LOC121046842 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115314400|UniProtKB=A0ACM8G3P3 A0ACM8G3P3 LOC115314400 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC chromatin binding#GO:0003682;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890 protein-containing complex#GO:0032991;PcG protein complex#GO:0031519;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC120846500|UniProtKB=A0ACM8F284 A0ACM8F284 LOC120846500 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8031667|UniProtKB=A0ACM8EGZ7 A0ACM8EGZ7 LOC8031667 PTHR45750:SF5 GH11602P HISTONE ACETYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 Notch signaling pathway#P00045>CoA#P01100 IXOSC|EnsemblGenome=LOC8024715|UniProtKB=A0ACM8E3I5 A0ACM8E3I5 LOC8024715 PTHR16023:SF0 TAX1 BINDING PROTEIN-RELATED PROTEIN VAC14 HOMOLOG metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115317184|UniProtKB=A0ACM8DXB8 A0ACM8DXB8 LOC115317184 PTHR24364:SF28 LP06937P MEMBRANE GLYCOPROTEIN LIG-1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115328397|UniProtKB=A0ACM8FD79 A0ACM8FD79 LOC115328397 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029502|UniProtKB=A0ACM8FH93 A0ACM8FH93 LOC8029502 PTHR10640:SF7 METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120848890|UniProtKB=A0ACM8G5F9 A0ACM8G5F9 LOC120848890 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120843111|UniProtKB=A0ACM8EWE6 A0ACM8EWE6 LOC120843111 PTHR11532:SF96 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D-LIKE PROTEIN metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 IXOSC|EnsemblGenome=LOC8043199|UniProtKB=A0ACM8ENM3 A0ACM8ENM3 LOC8043199 PTHR22829:SF5 DEP DOMAIN PROTEIN LYSOSOMAL CHOLESTEROL SIGNALING PROTEIN negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;negative regulation of signal transduction#GO:0009968;regulation of BMP signaling pathway#GO:0030510;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC120844220|UniProtKB=A0ACM8EY48 A0ACM8EY48 LOC120844220 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8024794|UniProtKB=A0ACM8DMH0 A0ACM8DMH0 LOC8024794 PTHR12053:SF4 PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED CARBOXYPEPTIDASE Q catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;metalloexopeptidase activity#GO:0008235 catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8023290|UniProtKB=A0ACM8FEE7 A0ACM8FEE7 LOC8023290 PTHR16036:SF2 ANKYRIN REPEAT AND ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 TRNA ENDONUCLEASE ANKZF1 RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;rescue of stalled cytosolic ribosome#GO:0072344;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle disassembly#GO:1903008;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;protein catabolic process#GO:0030163;translation#GO:0006412;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8033430|UniProtKB=A0ACM8DQQ4 A0ACM8DQQ4 eIF3d1 PTHR12399:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC121833419|UniProtKB=A0ACM8FKN7 A0ACM8FKN7 LOC121833419 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041603|UniProtKB=A0ACM8ECJ1 A0ACM8ECJ1 LOC8041603 PTHR11240:SF22 RIBONUCLEASE T2 RIBONUCLEASE X25 nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC115325539|UniProtKB=A0ACM8G2I8 A0ACM8G2I8 LOC115325539 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115328425|UniProtKB=A0ACM8EYS3 A0ACM8EYS3 LOC115328425 PTHR37162:SF10 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028565|UniProtKB=A0ACM8EAX6 A0ACM8EAX6 Vps2 PTHR10476:SF4 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2A macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;late endosome to vacuole transport#GO:0045324;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8033822|UniProtKB=A0ACM8F1A0 A0ACM8F1A0 GluRS-m PTHR43311:SF2 GLUTAMATE--TRNA LIGASE NONDISCRIMINATING GLUTAMYL-TRNA SYNTHETASE EARS2, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 IXOSC|EnsemblGenome=LOC8030656|UniProtKB=A0ACM8FLV5 A0ACM8FLV5 LOC8030656 PTHR18966:SF594 IONOTROPIC GLUTAMATE RECEPTOR IONOTROPIC RECEPTOR 93A neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8041787|UniProtKB=A0ACM8DKS5 A0ACM8DKS5 LOC8041787 PTHR10721:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM44 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 transporter#PC00227 IXOSC|EnsemblGenome=LOC120845803|UniProtKB=A0ACM8F070 A0ACM8F070 LOC120845803 PTHR23333:SF20 UBX DOMAIN CONTAINING PROTEIN GH01724P binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 establishment of spindle localization#GO:0051293;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;establishment of cell polarity#GO:0030010;primary metabolic process#GO:0044238;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;organelle localization#GO:0051640;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of mitotic spindle localization#GO:0040001;organelle organization#GO:0006996;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;cellular component organization#GO:0016043;establishment of organelle localization#GO:0051656;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;establishment or maintenance of cell polarity#GO:0007163;cellular localization#GO:0051641;spindle localization#GO:0051653 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC121835450|UniProtKB=A0ACM8FU54 A0ACM8FU54 LOC121835450 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315482|UniProtKB=A0ACM8DME3 A0ACM8DME3 LOC8026572 PTHR43289:SF6 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED SERINE_THREONINE KINASE 31 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115328050|UniProtKB=A0ACM8E914 A0ACM8E914 LOC115328050 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332262|UniProtKB=A0ACM8F058 A0ACM8F058 LOC115332262 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121046641|UniProtKB=A0ACM8FED1 A0ACM8FED1 LOC121046641 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC115332992|UniProtKB=A0ACM8ES38 A0ACM8ES38 LOC115332992 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115321909|UniProtKB=A0ACM8E1J3 A0ACM8E1J3 LOC115321909 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8031239|UniProtKB=A0ACM8F655 A0ACM8F655 LOC8031239 PTHR22715:SF0 TRANSFORMING GROWTH FACTOR BETA REGULATED GENE 1 TRANSFORMING GROWTH FACTOR BETA REGULATOR 1 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 growth factor#PC00112;intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8038135|UniProtKB=A0ACM8G1G0 A0ACM8G1G0 LOC8038135 PTHR45850:SF2 SORTING NEXIN FAMILY MEMBER SORTING NEXIN-5 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8028094|UniProtKB=A0ACM8DJK4 A0ACM8DJK4 LOC8028094 PTHR13064:SF6 TRANSMEMBRANE PROTEIN 9 FAMILY MEMBER TRANSMEMBRANE PROTEIN 9 IXOSC|EnsemblGenome=LOC115311009|UniProtKB=A0ACM8DQJ7 A0ACM8DQJ7 LOC115311009 PTHR14699:SF0 STI2 PROTEIN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 21 HOMOLOG intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;protein localization to cilium#GO:0061512;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;protein localization to organelle#GO:0033365;microtubule-based movement#GO:0007018;cellular component organization#GO:0016043 protein-containing complex#GO:0032991;intraciliary transport particle A#GO:0030991;intraciliary transport particle#GO:0030990 IXOSC|EnsemblGenome=LOC120847078|UniProtKB=A0ACM8FQW8 A0ACM8FQW8 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8042842|UniProtKB=A0ACM8DKZ4 A0ACM8DKZ4 LOC8042842 PTHR22770:SF48 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121838023|UniProtKB=A0ACM8G693 A0ACM8G693 LOC121838023 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115317757|UniProtKB=A0ACM8DXY9 A0ACM8DXY9 LOC115317757 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC120840045|UniProtKB=A0ACM8EN50 A0ACM8EN50 LOC120840045 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849004|UniProtKB=A0ACM8F753 A0ACM8F753 LOC120849004 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115312726|UniProtKB=A0ACM8DSI6 A0ACM8DSI6 LOC115312726 PTHR20426:SF0 RIBOSOME BIOGENESIS PROTEIN TSR3 HOMOLOG 18S RRNA AMINOCARBOXYPROPYLTRANSFERASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a rRNA#GO:0140102 RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115324551|UniProtKB=A0ACM8E4U1 A0ACM8E4U1 LOC115324551 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045980|UniProtKB=A0ACM8G7B2 A0ACM8G7B2 LOC121045980 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8043659|UniProtKB=A0ACM8F0B6 A0ACM8F0B6 LOC8043659 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 reductase#PC00198 IXOSC|EnsemblGenome=LOC8037667|UniProtKB=A0ACM8DM59 A0ACM8DM59 LOC8037667 PTHR47464:SF2 MACOILIN MACOILIN IXOSC|EnsemblGenome=LOC115312127|UniProtKB=A0ACM8DRL0 A0ACM8DRL0 LOC115312127 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8035852|UniProtKB=A0ACM8FGS7 A0ACM8FGS7 LOC8035852 PTHR15138:SF14 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;Huntington disease#P00029>TAFII130#P00806;General transcription regulation#P00023>TBP-associated factors#P00658 IXOSC|EnsemblGenome=LOC120841455|UniProtKB=A0ACM8FLE1 A0ACM8FLE1 LOC120841455 PTHR14911:SF13 THUMP DOMAIN-CONTAINING TRNA (GUANINE(6)-N(2))-METHYLTRANSFERASE THUMP3 tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC115318713|UniProtKB=A0ACM8DYV6 A0ACM8DYV6 LOC115318713 PTHR35617:SF4 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN TYR RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833135|UniProtKB=A0ACM8FJP2 A0ACM8FJP2 LOC121833135 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC8033460|UniProtKB=A0ACM8DP01 A0ACM8DP01 LOC8033460 PTHR12356:SF18 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 2 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8051200|UniProtKB=A0ACM8EFC5 A0ACM8EFC5 Ufl1 PTHR31057:SF0 E3 UFM1-PROTEIN LIGASE 1 E3 UFM1-PROTEIN LIGASE 1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 macroautophagy#GO:0016236;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;autophagy#GO:0006914;response to stress#GO:0006950;reticulophagy#GO:0061709;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8031243|UniProtKB=A0ACM8E2L3 A0ACM8E2L3 LOC8031243 PTHR46016:SF1 ZINC FINGER, RING/FYVE/PHD-TYPE ZINC FINGER PROTEIN 313 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 IXOSC|EnsemblGenome=LOC115324445|UniProtKB=A0ACM8EG81 A0ACM8EG81 LOC115324445 PTHR19325:SF577 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING HIG-ANCHORING SCAFFOLD PROTEIN, ISOFORM G defense/immunity protein#PC00090;complement component#PC00078 IXOSC|EnsemblGenome=LOC8030058|UniProtKB=A0ACM8DMC1 A0ACM8DMC1 LOC8030058 PTHR24365:SF530 TOLL-LIKE RECEPTOR TOLL-9, ISOFORM A molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121836037|UniProtKB=A0ACM8FY42 A0ACM8FY42 LOC121836037 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8039825|UniProtKB=A0ACM8FFI9 A0ACM8FFI9 LOC8039825 PTHR42886:SF96 RE40534P-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 hydrolase activity#GO:0016787;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;transferase activity#GO:0016740;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629 lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120846707|UniProtKB=A0ACM8F3V8 A0ACM8F3V8 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8034357|UniProtKB=A0ACM8F9Q3 A0ACM8F9Q3 PTHR21422:SF9 RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT RAB3 GTPASE-ACTIVATING PROTEIN CATALYTIC SUBUNIT nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 positive regulation of cellular component organization#GO:0051130;regulation of autophagosome assembly#GO:2000785;positive regulation of organelle organization#GO:0010638;positive regulation of metabolic process#GO:0009893;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;regulation of cellular component biogenesis#GO:0044087;positive regulation of macroautophagy#GO:0016239;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of catabolic process#GO:0009894;regulation of macroautophagy#GO:0016241;positive regulation of catabolic process#GO:0009896;positive regulation of biological process#GO:0048518;regulation of organelle assembly#GO:1902115;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;positive regulation of autophagy#GO:0010508;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089 G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8037321|UniProtKB=A0ACM8DY75 A0ACM8DY75 LOC8037321 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8034144|UniProtKB=A0ACM8EFM8 A0ACM8EFM8 eIF5B PTHR43381:SF4 TRANSLATION INITIATION FACTOR IF-2-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 5B translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8051851|UniProtKB=A0ACM8FM43 A0ACM8FM43 LOC8051851 PTHR11849:SF304 ETS DNA-BINDING PROTEIN D-ETS-3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8035386|UniProtKB=A0ACM8FXN6 A0ACM8FXN6 LOC8035386 PTHR13217:SF11 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 5 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;endothelial cell migration#GO:0043542;cell motility#GO:0048870;cell migration#GO:0016477 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115331022|UniProtKB=A0ACM8EBM0 A0ACM8EBM0 LOC115331022 PTHR46452:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 3 protein binding#GO:0005515;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695 IXOSC|EnsemblGenome=LOC8024399|UniProtKB=A0ACM8EDU7 A0ACM8EDU7 LOC8024399 PTHR24403:SF110 ZINC FINGER PROTEIN LD15904P double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8025422|UniProtKB=A0ACM8DRN6 A0ACM8DRN6 PTHR23079:SF55 RNA-DEPENDENT RNA POLYMERASE RNA-DIRECTED RNA POLYMERASE catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8035161|UniProtKB=A0ACM8EFG4 A0ACM8EFG4 RpL18A PTHR10052:SF1 60S RIBOSOMAL PROTEIN L18A LARGE RIBOSOMAL SUBUNIT PROTEIN EL20 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8023146|UniProtKB=A0ACM8F6N4 A0ACM8F6N4 LOC8023146 PTHR21419:SF30 FAMILY NOT NAMED FAM234A_B BETA-PROPELLER DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838832|UniProtKB=A0ACM8EKR4 A0ACM8EKR4 LOC120838832 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC120840931|UniProtKB=A0ACM8FX00 A0ACM8FX00 LOC120840931 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023 synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC115326880|UniProtKB=A0ACM8E743 A0ACM8E743 LOC115326880 PTHR13430:SF4 AUTOPHAGY-RELATED PROTEIN 13 AUTOPHAGY-RELATED PROTEIN 13 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;localization#GO:0051179;cellular component organization#GO:0016043;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056 protein kinase complex#GO:1902911;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;autophagosome#GO:0005776;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8052624|UniProtKB=A0ACM8DZ43 A0ACM8DZ43 PTHR10501:SF13 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A RNA binding#GO:0003723;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;U1 snRNP#GO:0005685;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 mRNA splicing#P00058>U2#P01478;mRNA splicing#P00058>U1#P01479 IXOSC|EnsemblGenome=LOC115323511|UniProtKB=A0ACM8F9Y0 A0ACM8F9Y0 LOC115323511 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757 glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=LOC115324880|UniProtKB=A0ACM8FF19 A0ACM8FF19 LOC115324880 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121836565|UniProtKB=A0ACM8G0G3 A0ACM8G0G3 LOC121836565 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120838800|UniProtKB=A0ACM8FCJ1 A0ACM8FCJ1 LOC120838800 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8052339|UniProtKB=A0ACM8DUZ7 A0ACM8DUZ7 LOC8052339 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115328054|UniProtKB=A0ACM8F1T7 A0ACM8F1T7 LOC115328054 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8043439|UniProtKB=A0ACM8FXW5 A0ACM8FXW5 LOC8043439 PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED dicarboxylic acid transmembrane transporter activity#GO:0005310;succinate transmembrane transporter activity#GO:0015141;citrate transmembrane transporter activity#GO:0015137;C4-dicarboxylate transmembrane transporter activity#GO:0015556;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 succinate transport#GO:0015744;dicarboxylic acid transport#GO:0006835;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;citrate transport#GO:0015746;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;tricarboxylic acid transport#GO:0006842 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC115328153|UniProtKB=A0ACM8F0C5 A0ACM8F0C5 LOC115328153 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115311910|UniProtKB=A0ACM8EZY0 A0ACM8EZY0 LOC115311910 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115316963|UniProtKB=A0ACM8G4X3 A0ACM8G4X3 LOC115316963 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8051747|UniProtKB=A0ACM8FL09 A0ACM8FL09 LOC8051747 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of protein metabolic process#GO:0051246;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;deaminase#PC00088;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041333|UniProtKB=A0ACM8F4E2 A0ACM8F4E2 LOC8041333 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;peptidase activity#GO:0008233;exopeptidase activity#GO:0008238;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120849144|UniProtKB=A0ACM8F689 A0ACM8F689 LOC120849144 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8040670|UniProtKB=A0ACM8DNR5 A0ACM8DNR5 LOC8040670 PTHR15976:SF16 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA XPG-I DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842879|UniProtKB=A0ACM8EUR3 A0ACM8EUR3 LOC120842879 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033829|UniProtKB=A0ACM8DXR9 A0ACM8DXR9 HtrA2 PTHR22939:SF132 SERINE PROTEASE FAMILY S1C HTRA-RELATED SERINE PROTEASE HTRA2, MITOCHONDRIAL serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;regulation of programmed cell death#GO:0043067;cell death#GO:0008219;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;proteolysis#GO:0006508;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of apoptotic process#GO:0043065;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of apoptotic process#GO:0042981 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8029145|UniProtKB=A0ACM8DHN2 A0ACM8DHN2 LOC8029145 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841439|UniProtKB=A0ACM8F277 A0ACM8F277 LOC8027330 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120848463|UniProtKB=A0ACM8FKB2 A0ACM8FKB2 LOC120848463 PTHR13312:SF0 HIV-INDUCED PROTEIN-7-LIKE PROTEASE UBIQUITIN THIOESTERASE OTU1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to unfolded protein#GO:0006986;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC121836555|UniProtKB=A0ACM8G0E7 A0ACM8G0E7 LOC121836555 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8035131|UniProtKB=A0ACM8FFT8 A0ACM8FFT8 PTHR11034:SF62 N-MYC DOWNSTREAM REGULATED GH09802P cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115323194|UniProtKB=A0ACM8F216 A0ACM8F216 LOC115323194 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115319525|UniProtKB=A0ACM8ETF2 A0ACM8ETF2 LOC115319525 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032416|UniProtKB=A0ACM8DJE2 A0ACM8DJE2 LOC8032416 PTHR32001:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT KCP2 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058 IXOSC|EnsemblGenome=LOC8035717|UniProtKB=A0ACM8FMJ5 A0ACM8FMJ5 PTHR24410:SF51 HL07962P-RELATED BTB DOMAIN-CONTAINING PROTEIN-RELATED defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC120842416|UniProtKB=A0ACM8FFE1 A0ACM8FFE1 LOC120842416 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837033|UniProtKB=A0ACM8G1J4 A0ACM8G1J4 LOC121837033 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC120848776|UniProtKB=A0ACM8F6G1 A0ACM8F6G1 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8028224|UniProtKB=A0ACM8DJK5 A0ACM8DJK5 PTHR24070:SF69 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY FI18258P1 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8031211|UniProtKB=A0ACM8F8Q8 A0ACM8F8Q8 LOC8031211 PTHR22625:SF72 PLEXIN PLEXIN A, ISOFORM A signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cell junction assembly#GO:0034329;cell development#GO:0048468;synapse assembly#GO:0007416;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;positive regulation of cell development#GO:0010720;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;neuron projection morphogenesis#GO:0048812;regulation of cell differentiation#GO:0045595;regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;axon guidance#GO:0007411;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;positive regulation of axonogenesis#GO:0050772;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;signaling#GO:0023052;cell differentiation#GO:0030154;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;system development#GO:0048731;regulation of nervous system development#GO:0051960;cell communication#GO:0007154;regulation of cell motility#GO:2000145;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;developmental process#GO:0032502;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell adhesion#GO:0007162 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8038307|UniProtKB=A0ACM8DRM9 A0ACM8DRM9 ND-ACP PTHR20863:SF80 ACYL CARRIER PROTEIN ACYL CARRIER PROTEIN, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;molecular carrier activity#GO:0140104 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8033638|UniProtKB=A0ACM8ECZ0 A0ACM8ECZ0 LOC8033638 PTHR14002:SF65 ENDOGLIN/TGF-BETA RECEPTOR TYPE III TRANSFORMING GROWTH FACTOR BETA RECEPTOR TYPE 3-LIKE transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8039133|UniProtKB=A0ACM8EKW5 A0ACM8EKW5 tefu PTHR37079:SF4 SERINE/THREONINE-PROTEIN KINASE ATM SERINE_THREONINE-PROTEIN KINASE ATM response to stimulus#GO:0050896;response to radiation#GO:0009314;response to ionizing radiation#GO:0010212;response to abiotic stimulus#GO:0009628 chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120849494|UniProtKB=A0ACM8F8V7 A0ACM8F8V7 LOC120849494 PTHR11214:SF411 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120847030|UniProtKB=A0ACM8F3K6 A0ACM8F3K6 LOC120847030 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037020|UniProtKB=A0ACM8E0Q5 A0ACM8E0Q5 PICK1 PTHR12141:SF1 ARFAPTIN-RELATED PRKCA-BINDING PROTEIN molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;regulation of endocytosis#GO:0030100;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;dendritic spine organization#GO:0097061;establishment of protein localization#GO:0045184;positive regulation of transport#GO:0051050;protein transport#GO:0015031;cellular localization#GO:0051641;receptor clustering#GO:0043113;positive regulation of cellular component organization#GO:0051130;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;neuron projection organization#GO:0106027;regulation of organelle organization#GO:0033043;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;positive regulation of endocytosis#GO:0045807;regulation of actin filament organization#GO:0110053;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;localization#GO:0051179;localization within membrane#GO:0051668;synapse organization#GO:0050808;postsynapse organization#GO:0099173;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of supramolecular fiber organization#GO:1902903 asymmetric synapse#GO:0032279;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;synaptic vesicle#GO:0008021;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;postsynaptic density#GO:0014069;endomembrane system#GO:0012505;neuron to neuron synapse#GO:0098984;transport vesicle#GO:0030133;postsynaptic specialization#GO:0099572;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;cell projection#GO:0042995;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;organelle subcompartment#GO:0031984;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;trans-Golgi network membrane#GO:0032588;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;neuron projection#GO:0043005;cell junction#GO:0030054 vesicle coat protein#PC00235 Ionotropic glutamate receptor pathway#P00037>PICK#P01012 IXOSC|EnsemblGenome=LOC115310213|UniProtKB=A0ACM8DPI0 A0ACM8DPI0 LOC115310213 PTHR37162:SF11 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121836423|UniProtKB=A0ACM8FZK4 A0ACM8FZK4 LOC121836423 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037868|UniProtKB=A0ACM8EGS9 A0ACM8EGS9 LOC8037868 PTHR10131:SF153 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053535|UniProtKB=A0ACM8E2M8 A0ACM8E2M8 LOC8053535 PTHR19858:SF0 WD40 REPEAT PROTEIN PERIODIC TRYPTOPHAN PROTEIN 2 HOMOLOG organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364 90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8039382|UniProtKB=A0ACM8EEK1 A0ACM8EEK1 PTHR11686:SF77 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;metabolic process#GO:0008152;sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8024959|UniProtKB=A0ACM8FM95 A0ACM8FM95 LOC8024959 PTHR22776:SF49 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120840441|UniProtKB=A0ACM8EPI8 A0ACM8EPI8 LOC120840441 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8040010|UniProtKB=A0ACM8DV35 A0ACM8DV35 LOC8040010 PTHR11999:SF68 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE HISTIDINE DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;lyase activity#GO:0016829 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;amine metabolic process#GO:0009308;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144;decarboxylase#PC00089 CCKR signaling map#P06959>HDC#G07262;CCKR signaling map#P06959>HDC#G06969;Histamine synthesis#P04387>Histidine decarboxylase#P04493 IXOSC|EnsemblGenome=LOC120847086|UniProtKB=A0ACM8F3X9 A0ACM8F3X9 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8025827|UniProtKB=A0ACM8EM02 A0ACM8EM02 LOC8025827 PTHR45921:SF6 IP01054P C15 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8035794|UniProtKB=A0ACM8G481 A0ACM8G481 LOC8035794 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8043609|UniProtKB=A0ACM8FBH4 A0ACM8FBH4 PTHR21579:SF20 PROTEIN TINCAR PROTEIN TINCAR IXOSC|EnsemblGenome=LOC8039341|UniProtKB=A0ACM8ETX8 A0ACM8ETX8 LOC8039341 PTHR11839:SF15 UDP/ADP-SUGAR PYROPHOSPHATASE URIDINE DIPHOSPHATE GLUCOSE PYROPHOSPHATASE NUDT14 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196 IXOSC|EnsemblGenome=LOC120838432|UniProtKB=A0ACM8EJS3 A0ACM8EJS3 LOC120838432 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8039553|UniProtKB=A0ACM8F940 A0ACM8F940 LOC8039553 PTHR22722:SF14 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED MEGALIN, ISOFORM A binding#GO:0005488;hormone binding#GO:0042562 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8030378|UniProtKB=A0ACM8DGW8 A0ACM8DGW8 LOC8030378 PTHR31873:SF6 L-ASPARTATE DEHYDROGENASE-RELATED ASPARTATE DEHYDROGENASE DOMAIN-CONTAINING PROTEIN dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8035002|UniProtKB=A0ACM8E430 A0ACM8E430 PSR PTHR12480:SF32 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD BIFUNCTIONAL ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD6 phagocytosis#GO:0006909;transport#GO:0006810;import into cell#GO:0098657;endocytosis#GO:0006897;establishment of localization#GO:0051234;localization#GO:0051179 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8028650|UniProtKB=A0ACM8E1N9 A0ACM8E1N9 LOC8028650 PTHR24372:SF80 GLYCOPROTEIN HORMONE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8023971|UniProtKB=A0ACM8DV11 A0ACM8DV11 LOC8023971 PTHR19957:SF3 SYNTAXIN SYNTAXIN-5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 organelle#GO:0043226;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 SNARE protein#PC00034 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091 IXOSC|EnsemblGenome=LOC8043889|UniProtKB=A0ACM8DXJ5 A0ACM8DXJ5 SrpRalpha PTHR43134:SF1 SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA SIGNAL RECOGNITION PARTICLE RECEPTOR SUBUNIT ALPHA ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;protein-containing complex binding#GO:0044877;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924 establishment of localization#GO:0051234;protein targeting#GO:0006605;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization#GO:0045184 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 G-protein#PC00020;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8023291|UniProtKB=A0ACM8DWD2 A0ACM8DWD2 LOC8023291 PTHR13622:SF16 THIAMIN PYROPHOSPHOKINASE SI:DKEY-6N6.2 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110 kinase#PC00137;transferase#PC00220 IXOSC|EnsemblGenome=LOC120837962|UniProtKB=A0ACM8EJN8 A0ACM8EJN8 LOC120837962 PTHR31399:SF0 DNA-DIRECTED PRIMASE / POLYMERASE PROTEIN DNA-DIRECTED PRIMASE_POLYMERASE PROTEIN DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA-directed DNA polymerase activity#GO:0003887;binding#GO:0005488;chromatin binding#GO:0003682 DNA synthesis involved in DNA replication#GO:0090592;mitochondrial DNA metabolic process#GO:0032042;DNA-templated DNA replication#GO:0006261;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;macromolecule metabolic process#GO:0043170;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;response to UV#GO:0009411;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;translesion synthesis#GO:0019985;replication fork processing#GO:0031297;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to radiation#GO:0009314;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8033976|UniProtKB=A0ACM8DIN7 A0ACM8DIN7 LOC8033976 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8027314|UniProtKB=A0ACM8F7R1 A0ACM8F7R1 LOC8027314 PTHR14140:SF45 E3 UBIQUITIN-PROTEIN LIGASE UHRF-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8028724|UniProtKB=A0ACM8FEM7 A0ACM8FEM7 LOC8028724 PTHR46607:SF1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 SEC14 DOMAIN AND SPECTRIN REPEAT-CONTAINING PROTEIN 1 phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;phospholipid binding#GO:0005543;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 IXOSC|EnsemblGenome=LOC115325899|UniProtKB=A0ACM8FSK4 A0ACM8FSK4 LOC115325899 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8031147|UniProtKB=A0ACM8DHZ0 A0ACM8DHZ0 LOC8031147 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 IXOSC|EnsemblGenome=LOC121833710|UniProtKB=A0ACM8FNC9 A0ACM8FNC9 LOC121833710 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8026835|UniProtKB=A0ACM8DN82 A0ACM8DN82 LOC8026835 PTHR11139:SF128 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED DNA-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of cellular process#GO:0050794;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell death#GO:0008219;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;telomere organization#GO:0032200;intracellular signal transduction#GO:0035556;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;apoptotic signaling pathway#GO:0097190;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;DNA repair#GO:0006281;DNA damage response#GO:0006974;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115326481|UniProtKB=A0ACM8ELV7 A0ACM8ELV7 LOC115326481 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121837758|UniProtKB=A0ACM8G502 A0ACM8G502 LOC121837758 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845772|UniProtKB=A0ACM8FV63 A0ACM8FV63 LOC120845772 PTHR20852:SF57 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE 2 CYTOPLASMIC ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 IXOSC|EnsemblGenome=LOC115329855|UniProtKB=A0ACM8G5D8 A0ACM8G5D8 LOC115329855 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121838242|UniProtKB=A0ACM8G8A4 A0ACM8G8A4 LOC121838242 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028558|UniProtKB=A0ACM8ELP3 A0ACM8ELP3 LOC8028558 PTHR22600:SF59 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE A hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 lysosome#GO:0005764;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8032061|UniProtKB=A0ACM8F1M5 A0ACM8F1M5 LOC8032061 PTHR11716:SF107 PHOSPHOLIPASE A2 FAMILY MEMBER PHOSPHOLIPASE A2 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC8053310|UniProtKB=A0ACM8E9J5 A0ACM8E9J5 LOC8053310 PTHR23140:SF4 RNA PROCESSING PROTEIN LD23810P INSULATOR SU(HW) MRNA ADAPTOR, ISOFORM B binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115326000|UniProtKB=A0ACM8F6C5 A0ACM8F6C5 LOC115326000 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8034689|UniProtKB=A0ACM8DY06 A0ACM8DY06 LOC8034689 PTHR22969:SF15 IKB KINASE FI05319P kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;immune system process#GO:0002376;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;activation of immune response#GO:0002253;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of response to external stimulus#GO:0032103;positive regulation of type I interferon production#GO:0032481;regulation of response to biotic stimulus#GO:0002831;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;activation of innate immune response#GO:0002218;regulation of cytokine production#GO:0001817;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;positive regulation of response to biotic stimulus#GO:0002833;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120850677|UniProtKB=A0ACM8FAT9 A0ACM8FAT9 LOC120850677 PTHR46403:SF2 TP53-REGULATED INHIBITOR OF APOPTOSIS 1 AT19138P-RELATED intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;lipid localization#GO:0010876;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;phospholipid transport#GO:0015914;membrane organization#GO:0061024;intermembrane phospholipid transfer#GO:0120010;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8035345|UniProtKB=A0ACM8F9K0 A0ACM8F9K0 LOC8035345 PTHR12994:SF17 SECERNIN LD30995P IXOSC|EnsemblGenome=LOC8053043|UniProtKB=A0ACM8DLL4 A0ACM8DLL4 Sumo PTHR10562:SF56 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8029744|UniProtKB=A0ACM8E5K6 A0ACM8E5K6 LOC8029744 PTHR10026:SF70 CYCLIN CYCLIN-Q cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 kinase modulator#PC00140;kinase activator#PC00138 IXOSC|EnsemblGenome=LOC121834398|UniProtKB=A0ACM8FPV4 A0ACM8FPV4 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314390|UniProtKB=A0ACM8ENB5 A0ACM8ENB5 LOC115314390 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036786|UniProtKB=A0ACM8F2E4 A0ACM8F2E4 LOC8036786 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115324818|UniProtKB=A0ACM8G547 A0ACM8G547 LOC115324818 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115308242|UniProtKB=A0ACM8DM82 A0ACM8DM82 LOC115308242 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED IXOSC|EnsemblGenome=LOC8030073|UniProtKB=A0ACM8DJ80 A0ACM8DJ80 LOC8030073 PTHR43355:SF2 FLAVIN REDUCTASE (NADPH) FLAVIN REDUCTASE (NADPH) oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 reductase#PC00198 IXOSC|EnsemblGenome=LOC8023966|UniProtKB=A0ACM8F385 A0ACM8F385 LOC8023966 PTHR48438:SF4 ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED ALPHA-(1,3)-FUCOSYLTRANSFERASE C IXOSC|EnsemblGenome=LOC8042716|UniProtKB=A0ACM8E1L9 A0ACM8E1L9 LOC8042716 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120849531|UniProtKB=A0ACM8F823 A0ACM8F823 PTHR12692:SF8 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED GH11935P metal ion transport#GO:0030001;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;protein metabolic process#GO:0019538;monoatomic cation transmembrane transport#GO:0098655;biosynthetic process#GO:0009058;monoatomic ion transmembrane transport#GO:0034220;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;transport#GO:0006810;metabolic process#GO:0008152;magnesium ion transport#GO:0015693 catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115328205|UniProtKB=A0ACM8G1T0 A0ACM8G1T0 LOC115328205 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120850211|UniProtKB=A0ACM8F9I7 A0ACM8F9I7 LOC120850211 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847616|UniProtKB=A0ACM8FKV8 A0ACM8FKV8 LOC120847616 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847579|UniProtKB=A0ACM8F5A7 A0ACM8F5A7 LOC120847579 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035018|UniProtKB=A0ACM8EUB3 A0ACM8EUB3 LOC8035018 PTHR15036:SF97 PIKACHURIN-LIKE PROTEIN SP2353, ISOFORM A nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organism development#GO:0007275;developmental process#GO:0032502;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;animal gross anatomical part developmental process#GO:0160108 cell junction#GO:0030054;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane#GO:0005886;extracellular matrix#GO:0031012;membrane#GO:0016020;external encapsulating structure#GO:0030312;cell periphery#GO:0071944;basement membrane#GO:0005604 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8043109|UniProtKB=A0ACM8EF97 A0ACM8EF97 LOC8043109 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039074|UniProtKB=A0ACM8DKA5 A0ACM8DKA5 LOC8039074 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829 polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;polyamine biosynthetic process#GO:0006596 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC120836862|UniProtKB=A0ACM8EG16 A0ACM8EG16 LOC120836862 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC120847765|UniProtKB=A0ACM8FSN3 A0ACM8FSN3 LOC120847765 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC120844761|UniProtKB=A0ACM8EZQ7 A0ACM8EZQ7 LOC120844761 PTHR19303:SF82 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120840880|UniProtKB=A0ACM8EQH8 A0ACM8EQH8 LOC120840880 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8026448|UniProtKB=A0ACM8DVM3 A0ACM8DVM3 LOC8026448 PTHR16318:SF1 GAMMA-SECRETASE SUBUNIT PEN-2 GAMMA-SECRETASE SUBUNIT PEN-2 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;catalytic complex#GO:1902494 Alzheimer disease-amyloid secretase pathway#P00003>Pen-2#P00089;Alzheimer disease-presenilin pathway#P00004>Pen-2#P00149 IXOSC|EnsemblGenome=LOC8042875|UniProtKB=A0ACM8DRK5 A0ACM8DRK5 LOC8042875 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120844393|UniProtKB=A0ACM8EYN6 A0ACM8EYN6 LOC120844393 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8038017|UniProtKB=A0ACM8DRU7 A0ACM8DRU7 LOC8038017 PTHR13459:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1-RELATED aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC8042179|UniProtKB=A0ACM8FC79 A0ACM8FC79 LOC8042179 PTHR12778:SF9 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED ACETYL-COENZYME A TRANSPORTER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC120849281|UniProtKB=A0ACM8F7U1 A0ACM8F7U1 LOC120849281 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115320347|UniProtKB=A0ACM8EPC6 A0ACM8EPC6 LOC120843782 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833193|UniProtKB=A0ACM8FIJ7 A0ACM8FIJ7 LOC121833193 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115323316|UniProtKB=A0ACM8EVZ1 A0ACM8EVZ1 LOC115323316 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850090|UniProtKB=A0ACM8FA06 A0ACM8FA06 LOC120850090 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8042561|UniProtKB=A0ACM8E451 A0ACM8E451 APC7 PTHR12558:SF36 CELL DIVISION CYCLE 16,23,27 ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of cellular component organization#GO:0051130;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of organelle organization#GO:0033043;positive regulation of cell cycle process#GO:0090068;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;metabolic process#GO:0008152;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome segregation#GO:0051983;regulation of chromosome separation#GO:1905818;positive regulation of cell cycle#GO:0045787;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell cycle phase transition#GO:1901987;cell division#GO:0051301;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8023084|UniProtKB=A0ACM8FQG1 A0ACM8FQG1 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8040389|UniProtKB=A0ACM8EDE5 A0ACM8EDE5 fliI PTHR11977:SF142 VILLIN PROTEIN FLIGHTLESS-1 HOMOLOG phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;regulation of protein-containing complex disassembly#GO:0043244;negative regulation of actin filament depolymerization#GO:0030835;actomyosin structure organization#GO:0031032;cell differentiation#GO:0030154;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;membraneless organelle assembly#GO:0140694;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;actin filament capping#GO:0051693;organelle assembly#GO:0070925;actin cytoskeleton organization#GO:0030036;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of supramolecular fiber organization#GO:1902903;myofibril assembly#GO:0030239;negative regulation of cellular component organization#GO:0051129;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;regulation of anatomical structure size#GO:0090066;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;regulation of biological quality#GO:0065008;striated muscle cell development#GO:0055002;regulation of actin filament length#GO:0030832;animal gross anatomical part developmental process#GO:0160108;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;actin polymerization or depolymerization#GO:0008154;negative regulation of protein-containing complex assembly#GO:0031333;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;cellular component assembly involved in morphogenesis#GO:0010927;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;negative regulation of organelle organization#GO:0010639;muscle cell development#GO:0055001 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC121835563|UniProtKB=A0ACM8FW19 A0ACM8FW19 LOC121835563 PTHR43686:SF1 SULFURTRANSFERASE-RELATED AMINOTRAN_5 DOMAIN-CONTAINING PROTEIN transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115309787|UniProtKB=A0ACM8F616 A0ACM8F616 LOC115309787 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8051326|UniProtKB=A0ACM8FSL9 A0ACM8FSL9 LOC8051326 PTHR45911:SF10 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of neurotransmitter secretion#GO:0046928;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of secretion#GO:0051046 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659 IXOSC|EnsemblGenome=LOC120850845|UniProtKB=A0ACM8F9U2 A0ACM8F9U2 LOC120850845 PTHR45938:SF14 ACP24A4-RELATED IXOLARIS IXOSC|EnsemblGenome=LOC8041896|UniProtKB=A0ACM8ET05 A0ACM8ET05 LOC8041896 PTHR47537:SF3 CUBILIN GH12701P plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8028413|UniProtKB=A0ACM8F2G1 A0ACM8F2G1 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8031263|UniProtKB=A0ACM8ES16 A0ACM8ES16 LOC8031263 PTHR22948:SF29 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8044067|UniProtKB=A0ACM8DYP4 A0ACM8DYP4 syd PTHR13886:SF4 JNK/SAPK-ASSOCIATED PROTEIN JNK-INTERACTING PROTEIN 3 signaling adaptor activity#GO:0035591;protein binding#GO:0005515;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;MAP kinase scaffold activity#GO:0005078;structural molecule activity#GO:0005198;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;cytoskeletal protein binding#GO:0008092;protein complex scaffold activity#GO:0140378 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121833768|UniProtKB=A0ACM8FML2 A0ACM8FML2 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115331192|UniProtKB=A0ACM8ED88 A0ACM8ED88 LOC115331192 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8029185|UniProtKB=A0ACM8DMF5 A0ACM8DMF5 LOC8029185 PTHR12333:SF0 COMM DOMAIN CONTAINING PROTEIN 10 COMM DOMAIN-CONTAINING PROTEIN 10 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC121836493|UniProtKB=A0ACM8FYV8 A0ACM8FYV8 LOC121836493 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8034691|UniProtKB=A0ACM8DZ58 A0ACM8DZ58 Tmem214 PTHR13448:SF0 TRANSMEMBRANE PROTEIN 214 TRANSMEMBRANE PROTEIN 214 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8037469|UniProtKB=A0ACM8DI52 A0ACM8DI52 LOC8037469 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;regulation of protein metabolic process#GO:0051246;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 IXOSC|EnsemblGenome=LOC120843905|UniProtKB=A0ACM8EX38 A0ACM8EX38 LOC120843905 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836423|UniProtKB=A0ACM8EFL6 A0ACM8EFL6 LOC120836423 PTHR13539:SF3 CALMODULIN-LYSINE N-METHYLTRANSFERASE CALMODULIN-LYSINE N-METHYLTRANSFERASE lysine N-methyltransferase activity#GO:0016278;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121836100|UniProtKB=A0ACM8FXB8 A0ACM8FXB8 LOC121836100 PTHR23233:SF84 SAL-LIKE PROTEIN FI23031P1-RELATED DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115327461|UniProtKB=A0ACM8EHF4 A0ACM8EHF4 LOC115327461 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;cellular process#GO:0009987;nervous system development#GO:0007399;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115313440|UniProtKB=A0ACM8EH65 A0ACM8EH65 LOC115313440 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC120848811|UniProtKB=A0ACM8F6I5 A0ACM8F6I5 LOC120848811 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 IXOSC|EnsemblGenome=LOC120847734|UniProtKB=A0ACM8F4S1 A0ACM8F4S1 LOC120847734 PTHR14679:SF1 GEM-ASSOCIATED PROTEIN 7 GEM-ASSOCIATED PROTEIN 7 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387 protein-containing complex#GO:0032991;Sm-like protein family complex#GO:0120114 IXOSC|EnsemblGenome=LOC8034616|UniProtKB=A0ACM8E8K5 A0ACM8E8K5 LOC8034616 PTHR10827:SF98 RETICULOCALBIN 45 KDA CALCIUM-BINDING PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calmodulin-related#PC00061;calcium-binding protein#PC00060 Gonadotropin-releasing hormone receptor pathway#P06664>AMPK#P06830 IXOSC|EnsemblGenome=LOC8041025|UniProtKB=A0ACM8FTA5 A0ACM8FTA5 dop PTHR24356:SF414 SERINE/THREONINE-PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8039538|UniProtKB=A0ACM8F7Z5 A0ACM8F7Z5 LOC8039538 PTHR10316:SF40 MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED LD27118P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell communication#GO:0007154;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of biological quality#GO:0065008;regulation of protein localization to membrane#GO:1905475;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;adherens junction#GO:0005912;cell junction#GO:0030054;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell-cell junction#GO:0005911 IXOSC|EnsemblGenome=LOC8027230|UniProtKB=A0ACM8EDL4 A0ACM8EDL4 LOC8027230 PTHR13832:SF565 PROTEIN PHOSPHATASE 2C PROTEIN-SERINE_THREONINE PHOSPHATASE catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC120849777|UniProtKB=A0ACM8G2L8 A0ACM8G2L8 LOC120849777 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053396|UniProtKB=A0ACM8FHK8 A0ACM8FHK8 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8034041|UniProtKB=A0ACM8G7Y4 A0ACM8G7Y4 Atf-2 PTHR19304:SF47 CYCLIC-AMP RESPONSE ELEMENT BINDING PROTEIN ACTIVATING TRANSCRIPTION FACTOR-2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC120838890|UniProtKB=A0ACM8FYL4 A0ACM8FYL4 LOC120838890 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115329447|UniProtKB=A0ACM8EVC1 A0ACM8EVC1 LOC115329447 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115330148|UniProtKB=A0ACM8EQ22 A0ACM8EQ22 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120846883|UniProtKB=A0ACM8F3I4 A0ACM8F3I4 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8023908|UniProtKB=A0ACM8FD01 A0ACM8FD01 LOC8023908 PTHR12268:SF14 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN-1 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120847369|UniProtKB=A0ACM8FIY7 A0ACM8FIY7 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837938|UniProtKB=A0ACM8EI49 A0ACM8EI49 LOC120837938 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8034028|UniProtKB=A0ACM8DIR4 A0ACM8DIR4 LOC8034028 PTHR12771:SF74 ENGULFMENT AND CELL MOTILITY CED-12 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8026999|UniProtKB=A0ACM8EBX8 A0ACM8EBX8 Vps39 PTHR12894:SF49 CNH DOMAIN CONTAINING VAM6_VPS39-LIKE PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;small GTPase binding#GO:0031267 process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;localization#GO:0051179;vacuole fusion#GO:0097576;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;macroautophagy#GO:0016236;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996 membrane#GO:0016020;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle tethering complex#GO:0099023;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC121836625|UniProtKB=A0ACM8G0P5 A0ACM8G0P5 LOC121836625 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027252|UniProtKB=A0ACM8DNP6 A0ACM8DNP6 LOC8027252 PTHR19842:SF0 G BETA-LIKE PROTEIN GBL TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 regulation of actin filament-based process#GO:0032970;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of actin cytoskeleton organization#GO:0032956;TOR signaling#GO:0031929;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;signaling#GO:0023052 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201 IXOSC|EnsemblGenome=LOC8028317|UniProtKB=A0ACM8E7A6 A0ACM8E7A6 LOC8028317 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036167|UniProtKB=A0ACM8EDF8 A0ACM8EDF8 LOC8036167 PTHR45791:SF1 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 1 calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;magnesium ion binding#GO:0000287;metal ion binding#GO:0046872 IXOSC|EnsemblGenome=LOC115312838|UniProtKB=A0ACM8ESV8 A0ACM8ESV8 LOC115312838 PTHR45749:SF35 ZINC FINGER MYM-TYPE PROTEIN 1 AC-LIKE TRANSPOSASE-RELATED IXOSC|EnsemblGenome=LOC8041289|UniProtKB=A0ACM8EIM3 A0ACM8EIM3 LOC8041289 PTHR12479:SF10 LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of membrane permeability#GO:0090559 lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 IXOSC|EnsemblGenome=LOC8025329|UniProtKB=A0ACM8E5D9 A0ACM8E5D9 LOC8025329 PTHR10985:SF77 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED PROTEIN HAIRY transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of neurogenesis#GO:0050767;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 IXOSC|EnsemblGenome=LOC8037400|UniProtKB=A0ACM8E4C0 A0ACM8E4C0 Hey PTHR10985:SF138 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED HAIRY_ENHANCER-OF-SPLIT RELATED WITH YRPW MOTIF PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cell surface receptor signaling pathway#GO:0007166;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;Notch signaling pathway#GO:0007219;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 IXOSC|EnsemblGenome=LOC8039626|UniProtKB=A0ACM8EPA5 A0ACM8EPA5 LOC8039626 PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED IXOSC|EnsemblGenome=LOC8028032|UniProtKB=A0ACM8EGQ3 A0ACM8EGQ3 LOC8028032 PTHR11071:SF582 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120841029|UniProtKB=A0ACM8EQU8 A0ACM8EQU8 LOC120841029 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838353|UniProtKB=A0ACM8EKK9 A0ACM8EKK9 LOC120838353 PTHR46370:SF1 GPALPP MOTIFS-CONTAINING PROTEIN 1 GPALPP MOTIFS-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8027776|UniProtKB=A0ACM8F9H6 A0ACM8F9H6 LOC8027776 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8029923|UniProtKB=A0ACM8ECC0 A0ACM8ECC0 LOC8029923 PTHR11964:SF1 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;biosynthetic process#GO:0009058 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;nucleotidyltransferase#PC00174 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 IXOSC|EnsemblGenome=LOC121835899|UniProtKB=A0ACM8FVL3 A0ACM8FVL3 LOC121835899 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025943|UniProtKB=A0ACM8FJ51 A0ACM8FJ51 Rab3-GEF PTHR13008:SF7 MAP-KINASE ACTIVATING DEATH DOMAIN PROTEIN MADD /DENN/AEX-3 C.ELEGANS MAP KINASE-ACTIVATING DEATH DOMAIN PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 Apoptosis signaling pathway#P00006>MADD#P00267 IXOSC|EnsemblGenome=LOC121838158|UniProtKB=A0ACM8G7Z7 A0ACM8G7Z7 LOC121838158 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026783|UniProtKB=A0ACM8DXZ2 A0ACM8DXZ2 LOC8026783 PTHR47958:SF215 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC115314380|UniProtKB=A0ACM8FDM9 A0ACM8FDM9 LOC115314380 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036406|UniProtKB=A0ACM8DK02 A0ACM8DK02 D12 PTHR23195:SF7 YEATS DOMAIN YEATS DOMAIN-CONTAINING PROTEIN 2 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;nucleus#GO:0005634;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC115323322|UniProtKB=A0ACM8G2Y1 A0ACM8G2Y1 LOC121837358 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115329299|UniProtKB=A0ACM8EAA5 A0ACM8EAA5 LOC115329299 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838144|UniProtKB=A0ACM8G6K3 A0ACM8G6K3 LOC121838144 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120848712|UniProtKB=A0ACM8F6A9 A0ACM8F6A9 LOC120848712 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8053367|UniProtKB=A0ACM8G6A9 A0ACM8G6A9 LOC8053367 PTHR11905:SF237 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN MIND-MELD, ISOFORM J metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120849872|UniProtKB=A0ACM8F8X9 A0ACM8F8X9 LOC120849872 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121046112|UniProtKB=A0ACM8FD95 A0ACM8FD95 LOC121046112 PTHR21421:SF29 GUSTATORY RECEPTOR GUSTATORY RECEPTOR 5A FOR TREHALOSE-RELATED system process#GO:0003008;multicellular organismal process#GO:0032501;nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of chemical stimulus#GO:0007606 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8023679|UniProtKB=A0ACM8EIA5 A0ACM8EIA5 LOC8023679 PTHR10188:SF43 L-ASPARAGINASE ISOASPARTYL PEPTIDASE_L-ASPARAGINASE amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8042488|UniProtKB=A0ACM8EHQ5 A0ACM8EHQ5 LOC8042488 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;binding#GO:0005488;tetrapyrrole binding#GO:0046906 response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629;response to stimulus#GO:0050896;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8037427|UniProtKB=A0ACM8DSB1 A0ACM8DSB1 LOC8037427 PTHR23104:SF17 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120845274|UniProtKB=A0ACM8F092 A0ACM8F092 LOC120845274 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120837948|UniProtKB=A0ACM8G8F0 A0ACM8G8F0 LOC120837948 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN transferase#PC00220;acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC120837685|UniProtKB=A0ACM8EJ08 A0ACM8EJ08 PTHR43313:SF65 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C SHORT-CHAIN DEHYDROGENASE_REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115325352|UniProtKB=A0ACM8ESB5 A0ACM8ESB5 LOC115325352 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC115328870|UniProtKB=A0ACM8E8T4 A0ACM8E8T4 LOC115328870 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115328150|UniProtKB=A0ACM8EPM0 A0ACM8EPM0 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8029037|UniProtKB=A0ACM8DSH3 A0ACM8DSH3 LOC8029037 PTHR24119:SF0 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 ACYL-COA-BINDING DOMAIN-CONTAINING PROTEIN 6 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;enzyme activator activity#GO:0008047;heterocyclic compound binding#GO:1901363;molecular function regulator activity#GO:0098772 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC121834748|UniProtKB=A0ACM8FRB2 A0ACM8FRB2 LOC121834748 PTHR36943:SF2 CCHC-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329823|UniProtKB=A0ACM8FWD0 A0ACM8FWD0 LOC115329823 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121836871|UniProtKB=A0ACM8G139 A0ACM8G139 LOC121836871 PTHR11267:SF106 T-BOX PROTEIN-RELATED T-RELATED PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 IXOSC|EnsemblGenome=LOC120846816|UniProtKB=A0ACM8F2H2 A0ACM8F2H2 LOC120846816 PTHR10264:SF136 BAND 7 PROTEIN-RELATED BAND 7 DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC115316299|UniProtKB=A0ACM8DWA7 A0ACM8DWA7 LOC115316299 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;binding#GO:0005488;catalytic activity#GO:0003824;small molecule binding#GO:0036094;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115320393|UniProtKB=A0ACM8E034 A0ACM8E034 LOC115320393 PTHR12892:SF11 FGF RECEPTOR ACTIVATING PROTEIN 1 ACYLTRANSFERASE PGAP2 glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120843000|UniProtKB=A0ACM8F353 A0ACM8F353 LOC8042669 PTHR15189:SF7 BRISC AND BRCA1-A COMPLEX MEMBER 2 BRISC AND BRCA1-A COMPLEX MEMBER 2 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC121837988|UniProtKB=A0ACM8G649 A0ACM8G649 LOC121837988 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8037860|UniProtKB=A0ACM8EH04 A0ACM8EH04 LOC8037860 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8037145|UniProtKB=A0ACM8DP24 A0ACM8DP24 LOC8037145 PTHR24012:SF928 RNA BINDING PROTEIN BRUNO 3, ISOFORM Q mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;regulation of mRNA metabolic process#GO:1903311;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121833044|UniProtKB=A0ACM8FJ97 A0ACM8FJ97 LOC121833044 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115311584|UniProtKB=A0ACM8F9N6 A0ACM8F9N6 LOC115311584 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8037139|UniProtKB=A0ACM8EPK0 A0ACM8EPK0 LOC8037139 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115321540|UniProtKB=A0ACM8E2B9 A0ACM8E2B9 LOC120837152 PTHR12588:SF0 MYOINOSITOL OXYGENASE INOSITOL OXYGENASE catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8030159|UniProtKB=A0ACM8DS70 A0ACM8DS70 LOC8030159 PTHR33662:SF3 OTU DEUBIQUITINASE WITH LINEAR LINKAGE-SPECIFICITY A-RELATED FIBROUS SHEATH CABYR-BINDING PROTEIN ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8025598|UniProtKB=A0ACM8DSK1 A0ACM8DSK1 LOC8025598 PTHR12655:SF10 ACYL-COA THIOESTERASE ACYL-COENZYME A THIOESTERASE 9, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity#GO:0003824;acyl-CoA hydrolase activity#GO:0016289;deacylase activity#GO:0160215;fatty acyl-CoA hydrolase activity#GO:0047617;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8032774|UniProtKB=A0ACM8DGT8 A0ACM8DGT8 LOC8032774 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC121835055|UniProtKB=A0ACM8FSP7 A0ACM8FSP7 LOC121835055 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042150|UniProtKB=A0ACM8E5R2 A0ACM8E5R2 LOC8042150 PTHR14445:SF36 GRB10 INTERACTING GYF PROTEIN FI03272P-RELATED translation regulator activity#GO:0045182 regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC115312143|UniProtKB=A0ACM8FAH1 A0ACM8FAH1 LOC115312143 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120839234|UniProtKB=A0ACM8G1W3 A0ACM8G1W3 LOC120839234 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8042068|UniProtKB=A0ACM8EM70 A0ACM8EM70 LOC8042068 PTHR10024:SF234 SYNAPTOTAGMIN SYNAPTOTAGMIN-15-RELATED lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543 transport#GO:0006810;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;localization#GO:0051179;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 IXOSC|EnsemblGenome=LOC8024485|UniProtKB=A0ACM8EG66 A0ACM8EG66 LOC8024485 PTHR11717:SF7 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC120846958|UniProtKB=A0ACM8F3E2 A0ACM8F3E2 LOC120846958 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052155|UniProtKB=A0ACM8DLZ4 A0ACM8DLZ4 LOC8052155 PTHR14534:SF3 VACUOLAR IMPORT AND DEGRADATION PROTEIN 24 GID COMPLEX SUBUNIT 4 HOMOLOG cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 IXOSC|EnsemblGenome=LOC115315464|UniProtKB=A0ACM8G352 A0ACM8G352 LOC115315464 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8040528|UniProtKB=A0ACM8EAP6 A0ACM8EAP6 LOC8040528 PTHR12022:SF0 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX 14 KD PROTEIN CYTOCHROME B-C1 COMPLEX SUBUNIT 7 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 respiratory chain complex III#GO:0045275;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836111|UniProtKB=A0ACM8FWS7 A0ACM8FWS7 LOC121836111 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115332517|UniProtKB=A0ACM8EYR1 A0ACM8EYR1 LOC115332517 PTHR46809:SF2 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN GH21273P IXOSC|EnsemblGenome=LOC8024908|UniProtKB=A0ACM8FQ08 A0ACM8FQ08 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC121833517|UniProtKB=A0ACM8FME2 A0ACM8FME2 LOC121833517 PTHR42687:SF1 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8033375|UniProtKB=A0ACM8EIF2 A0ACM8EIF2 LOC8033375 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8053564|UniProtKB=A0ACM8E8K7 A0ACM8E8K7 LOC8053564 PTHR15606:SF4 DNAJ HOMOLOG SUBFAMILY C MEMBER 8/LIPOPOLYSACCHARIDE SPECIFIC RESPONSE-7-RELATED DNAJ HOMOLOG SUBFAMILY C MEMBER 8 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8051106|UniProtKB=A0ACM8EC21 A0ACM8EC21 Dbct PTHR43178:SF18 LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED CHAIN ALPHA_KETOACID DEHYDROGENASE COMPLEX LIPOAMIDE ACYLTRANSFERASE COMPONENT OF BRANCHED-CHAIN ALPHA-KETO ACID DEHYDROGENASE COMPLEX, MITOCHONDRIAL acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC121838129|UniProtKB=A0ACM8G7W7 A0ACM8G7W7 LOC121838129 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC120839550|UniProtKB=A0ACM8FA23 A0ACM8FA23 LOC120839550 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115310288|UniProtKB=A0ACM8EXJ9 A0ACM8EXJ9 LOC115310288 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115309309|UniProtKB=A0ACM8DNI7 A0ACM8DNI7 LOC115309309 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121046361|UniProtKB=A0ACM8G8W2 A0ACM8G8W2 LOC121046361 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8027270|UniProtKB=A0ACM8E1V8 A0ACM8E1V8 LOC8027270 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC120851171|UniProtKB=A0ACM8FBG5 A0ACM8FBG5 LOC120851171 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8052050|UniProtKB=A0ACM8EAZ5 A0ACM8EAZ5 LOC8052050 PTHR12406:SF41 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 IPLA2 -RELATED TRIACYLGLYCEROL LIPASE carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;triacylglycerol lipase activity#GO:0004806;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503;homeostatic process#GO:0042592;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;neutral lipid catabolic process#GO:0046461;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid catabolic process#GO:0016042;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC115308401|UniProtKB=A0ACM8DMG6 A0ACM8DMG6 LOC115308401 PTHR11946:SF93 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8031779|UniProtKB=A0ACM8DIN8 A0ACM8DIN8 LOC8031779 PTHR48430:SF2 PARTNER OF XRN-2 PROTEIN 1 CDKN2A-INTERACTING PROTEIN N-TERMINAL-LIKE IXOSC|EnsemblGenome=LOC115310025|UniProtKB=A0ACM8EMK8 A0ACM8EMK8 LOC115310025 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121837195|UniProtKB=A0ACM8G2R4 A0ACM8G2R4 LOC121837195 PTHR46289:SF21 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053875|UniProtKB=A0ACM8DLR0 A0ACM8DLR0 LOC8053875 PTHR31501:SF7 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL PROTEIN 1 ion channel#PC00133 IXOSC|EnsemblGenome=LOC115318831|UniProtKB=A0ACM8DXJ2 A0ACM8DXJ2 LOC115318831 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120842707|UniProtKB=A0ACM8EUE9 A0ACM8EUE9 LOC120842707 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC120841481|UniProtKB=A0ACM8FMT6 A0ACM8FMT6 LOC120841481 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024797|UniProtKB=A0ACM8DX84 A0ACM8DX84 Paics PTHR43599:SF3 MULTIFUNCTIONAL PROTEIN ADE2 BIFUNCTIONAL PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE_PHOSPHORIBOSYLAMINOIMIDAZOLE SUCCINOCARBOXAMIDE SYNTHETASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8033384|UniProtKB=A0ACM8DHV3 A0ACM8DHV3 ifc PTHR12879:SF8 SPHINGOLIPID DELTA 4 DESATURASE/C-4 HYDROXYLASE PROTEIN DES2 SPHINGOLIPID DELTA(4)-DESATURASE DES1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;ceramide metabolic process#GO:0006672 hydroxylase#PC00122;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115312126|UniProtKB=A0ACM8EZT5 A0ACM8EZT5 LOC115312126 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120845403|UniProtKB=A0ACM8F1L0 A0ACM8F1L0 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327921|UniProtKB=A0ACM8G8X0 A0ACM8G8X0 LOC115327921 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121046038|UniProtKB=A0ACM8FCR3 A0ACM8FCR3 LOC121046038 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8033935|UniProtKB=A0ACM8EEN3 A0ACM8EEN3 LOC8033935 PTHR24210:SF0 LIM DOMAIN-CONTAINING PROTEIN LIM DOMAIN-CONTAINING PROTEIN cellular component organization#GO:0016043;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;cell adhesion#GO:0007155;positive regulation of signaling#GO:0023056;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 IXOSC|EnsemblGenome=LOC8035239|UniProtKB=A0ACM8DJP8 A0ACM8DJP8 LOC8035239 PTHR14009:SF13 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN LETM1 DOMAIN-CONTAINING PROTEIN 1 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8033621|UniProtKB=A0ACM8FXH7 A0ACM8FXH7 LOC8033621 PTHR12221:SF6 PESCADILLO - RELATED PESCADILLO HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843 nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;90S preribosome#GO:0030686;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8029096|UniProtKB=A0ACM8FGF1 A0ACM8FGF1 LOC8029096 PTHR23074:SF78 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A-LIKE 2 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 meiotic cell cycle#GO:0051321;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;reproductive process#GO:0022414;cytoskeleton organization#GO:0007010 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8031544|UniProtKB=A0ACM8F467 A0ACM8F467 LOC8031544 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115323635|UniProtKB=A0ACM8FJQ3 A0ACM8FJQ3 LOC115323635 PTHR11690:SF248 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC121833131|UniProtKB=A0ACM8FJM6 A0ACM8FJM6 LOC121833131 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8032349|UniProtKB=A0ACM8F641 A0ACM8F641 LOC8032349 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC120842031|UniProtKB=A0ACM8ESX7 A0ACM8ESX7 LOC120842031 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120836905|UniProtKB=A0ACM8EG43 A0ACM8EG43 LOC120836905 PTHR13568:SF4 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 60 IXOSC|EnsemblGenome=LOC120835972|UniProtKB=A0ACM8FNJ8 A0ACM8FNJ8 LOC120835972 PTHR10332:SF88 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;carbohydrate derivative transmembrane transporter activity#GO:1901505 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8037562|UniProtKB=A0ACM8F287 A0ACM8F287 LOC8037562 PTHR11177:SF408 CHITINASE ACIDIC MAMMALIAN CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8051737|UniProtKB=A0ACM8EF28 A0ACM8EF28 REPTOR PTHR21552:SF2 ADULT RETINA PROTEIN CREB3 REGULATORY FACTOR sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8025353|UniProtKB=A0ACM8G0H0 A0ACM8G0H0 LOC8025353 PTHR45865:SF2 E3 UBIQUITIN-PROTEIN LIGASE SHPRH FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE SHPRH catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 DNA damage response#GO:0006974;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120843924|UniProtKB=A0ACM8EX59 A0ACM8EX59 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8027332|UniProtKB=A0ACM8F1N1 A0ACM8F1N1 LOC8027332 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115314534|UniProtKB=A0ACM8DUD5 A0ACM8DUD5 LOC115314534 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8039758|UniProtKB=A0ACM8DSF3 A0ACM8DSF3 LOC8039758 PTHR12876:SF35 N4BP1-RELATED LD08718P-RELATED mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;RNA binding#GO:0003723;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC8037142|UniProtKB=A0ACM8E235 A0ACM8E235 LOC8037142 PTHR24073:SF352 DRAB5-RELATED RAS-RELATED PROTEIN RAB6 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cytosolic transport#GO:0016482;intra-Golgi vesicle-mediated transport#GO:0006891 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 G-protein#PC00020;small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120841632|UniProtKB=A0ACM8FDZ2 A0ACM8FDZ2 LOC120841632 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120842034|UniProtKB=A0ACM8ET02 A0ACM8ET02 LOC120842034 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838524|UniProtKB=A0ACM8EK71 A0ACM8EK71 LOC120838524 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;binding#GO:0005488;catalytic activity#GO:0003824;small molecule binding#GO:0036094;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053055|UniProtKB=A0ACM8E209 A0ACM8E209 LOC8053055 PTHR12837:SF15 POLY ADP-RIBOSE GLYCOHYDROLASE POLY(ADP-RIBOSE) GLYCOHYDROLASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;regulation of cellular response to stress#GO:0080135;ribonucleotide metabolic process#GO:0009259 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC121835884|UniProtKB=A0ACM8FVJ6 A0ACM8FVJ6 LOC121835884 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8024171|UniProtKB=A0ACM8DZF5 A0ACM8DZF5 LOC8024171 PTHR10155:SF16 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 2-LIKE PROTEIN protein binding#GO:0005515;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488 regulation of signaling#GO:0023051;cytokine-mediated signaling pathway#GO:0019221;negative regulation of signaling#GO:0023057;response to peptide#GO:1901652;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;negative regulation of cellular process#GO:0048523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;response to cytokine#GO:0034097;response to chemical#GO:0042221 kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC121836647|UniProtKB=A0ACM8FZK1 A0ACM8FZK1 LOC121836647 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050777|UniProtKB=A0ACM8DW47 A0ACM8DW47 LanA PTHR10574:SF449 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;tissue development#GO:0009888;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 IXOSC|EnsemblGenome=LOC8037403|UniProtKB=A0ACM8EAN2 A0ACM8EAN2 LOC8037403 PTHR12737:SF9 DIMETHYLARGININE DIMETHYLAMINOHYDROLASE GM09012P hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biological regulation#GO:0065007 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120838573|UniProtKB=A0ACM8FT33 A0ACM8FT33 LOC120838573 PTHR13420:SF7 UPF0235 PROTEIN C15ORF40 UPF0235 PROTEIN C15ORF40 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8028542|UniProtKB=A0ACM8DP15 A0ACM8DP15 LOC8028542 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120847629|UniProtKB=A0ACM8G539 A0ACM8G539 LOC120847629 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836107|UniProtKB=A0ACM8FY80 A0ACM8FY80 LOC121836107 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 transferase#PC00220 IXOSC|EnsemblGenome=LOC120844895|UniProtKB=A0ACM8F0Z8 A0ACM8F0Z8 LOC120844895 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842647|UniProtKB=A0ACM8G131 A0ACM8G131 LOC120842647 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115321094|UniProtKB=A0ACM8E1I6 A0ACM8E1I6 LOC115321094 PTHR21461:SF69 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120839573|UniProtKB=A0ACM8EN65 A0ACM8EN65 LOC120839573 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836817|UniProtKB=A0ACM8DNY8 A0ACM8DNY8 LOC8039114 PTHR12277:SF207 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PROTEIN ABHD13 catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;palmitoyl hydrolase activity#GO:0098599 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120849529|UniProtKB=A0ACM8F8B2 A0ACM8F8B2 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041518|UniProtKB=A0ACM8DUX3 A0ACM8DUX3 l(1)G0004 PTHR12826:SF13 RIBONUCLEASE Y RNA-BINDING PROTEIN PNO1 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC121834263|UniProtKB=A0ACM8FPX0 A0ACM8FPX0 PTHR24257:SF17 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER SUBFAMILY NOT NAMED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120839809|UniProtKB=A0ACM8EMK6 A0ACM8EMK6 LOC120839809 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8032700|UniProtKB=A0ACM8DGJ1 A0ACM8DGJ1 LOC8032700 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8038380|UniProtKB=A0ACM8E2F7 A0ACM8E2F7 LOC8038380 PTHR45672:SF2 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED PROTEIN DISULFIDE-ISOMERASE A5 catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853 protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8050666|UniProtKB=A0ACM8F7T9 A0ACM8F7T9 LOC8050666 PTHR10106:SF0 CYTOCHROME B561-RELATED LD36721P catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC120851166|UniProtKB=A0ACM8FA76 A0ACM8FA76 LOC120851166 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115308808|UniProtKB=A0ACM8F5K4 A0ACM8F5K4 LOC115308808 PTHR11610:SF200 LIPASE FI22312P1 lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8026876|UniProtKB=A0ACM8FKP5 A0ACM8FKP5 LOC8026876 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121047143|UniProtKB=A0ACM8G543 A0ACM8G543 LOC121047143 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8039443|UniProtKB=A0ACM8EG61 A0ACM8EG61 LOC8039443 PTHR12197:SF251 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD EG:BACR7C10.4 PROTEIN N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8024415|UniProtKB=A0ACM8DQ35 A0ACM8DQ35 Arl5 PTHR11711:SF31 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE 5 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein#PC00020 IXOSC|EnsemblGenome=LOC121045828|UniProtKB=A0ACM8FCC5 A0ACM8FCC5 LOC121045828 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121835665|UniProtKB=A0ACM8FW44 A0ACM8FW44 LOC121835665 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8037336|UniProtKB=A0ACM8FDL6 A0ACM8FDL6 LOC8037336 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;neurogenesis#GO:0022008;system development#GO:0048731;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120836875|UniProtKB=A0ACM8EG21 A0ACM8EG21 LOC120836875 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837773|UniProtKB=A0ACM8G641 A0ACM8G641 LOC121837773 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121837355|UniProtKB=A0ACM8G3B9 A0ACM8G3B9 LOC121837355 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC120846555|UniProtKB=A0ACM8F2E2 A0ACM8F2E2 LOC120846555 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8052908|UniProtKB=A0ACM8FRA7 A0ACM8FRA7 LOC8052908 PTHR24072:SF142 RHO FAMILY GTPASE RHOU, ISOFORM B pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 cellular response to stimulus#GO:0051716;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;actin filament-based process#GO:0030029;establishment or maintenance of cell polarity#GO:0007163;supramolecular fiber organization#GO:0097435;localization#GO:0051179;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;transport#GO:0006810;actin filament organization#GO:0007015;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC8036614|UniProtKB=A0ACM8DHK4 A0ACM8DHK4 LOC8036614 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic ion homeostasis#GO:0050801;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC120844524|UniProtKB=A0ACM8FPT1 A0ACM8FPT1 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843002|UniProtKB=A0ACM8EV50 A0ACM8EV50 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8034180|UniProtKB=A0ACM8DJ31 A0ACM8DJ31 LOC8034180 PTHR31637:SF7 2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE 2,3-BISPHOSPHOGLYCERATE-INDEPENDENT PHOSPHOGLYCERATE MUTASE cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853;phosphoglycerate mutase activity#GO:0004619;intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824 carbohydrate metabolic process#GO:0005975;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;mutase#PC00160 IXOSC|EnsemblGenome=LOC120850281|UniProtKB=A0ACM8F9N3 A0ACM8F9N3 LOC120850281 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121047502|UniProtKB=A0ACM8FGG8 A0ACM8FGG8 LOC121047502 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8029348|UniProtKB=A0ACM8E376 A0ACM8E376 LOC8029348 PTHR46423:SF1 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 RNA POLYMERASE II-ASSOCIATED PROTEIN 3 IXOSC|EnsemblGenome=LOC8026263|UniProtKB=A0ACM8FIG7 A0ACM8FIG7 LOC8026263 PTHR11920:SF335 GUANYLYL CYCLASE GUANYLATE CYCLASE peptide receptor activity#GO:0001653;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;molecular transducer activity#GO:0060089;lyase activity#GO:0016829 cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 lyase#PC00144;guanylate cyclase#PC00114 IXOSC|EnsemblGenome=LOC120844619|UniProtKB=A0ACM8F076 A0ACM8F076 LOC120844619 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120844905|UniProtKB=A0ACM8EZW2 A0ACM8EZW2 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120843951|UniProtKB=A0ACM8EXA3 A0ACM8EXA3 LOC120843951 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8052033|UniProtKB=A0ACM8EDN8 A0ACM8EDN8 LOC8052033 PTHR46071:SF2 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121835757|UniProtKB=A0ACM8FWG3 A0ACM8FWG3 LOC121835757 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025099|UniProtKB=A0ACM8EZH5 A0ACM8EZH5 LOC8025099 PTHR43097:SF16 GLUTAMINE-TRNA LIGASE GLUTAMINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 catalytic complex#GO:1902494;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 aminoacyl-tRNA synthetase#PC00047 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 IXOSC|EnsemblGenome=LOC8025282|UniProtKB=A0ACM8DXW0 A0ACM8DXW0 LOC8025282 PTHR48430:SF2 PARTNER OF XRN-2 PROTEIN 1 CDKN2A-INTERACTING PROTEIN N-TERMINAL-LIKE IXOSC|EnsemblGenome=LOC8035613|UniProtKB=A0ACM8FC05 A0ACM8FC05 LOC8035613 PTHR14164:SF12 PERICENTRIOLAR MATERIAL 1-RELATED PERICENTRIOLAR MATERIAL 1 PROTEIN cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115325565|UniProtKB=A0ACM8E4Y4 A0ACM8E4Y4 LOC115325565 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC115332408|UniProtKB=A0ACM8EDN4 A0ACM8EDN4 LOC115332408 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8051581|UniProtKB=A0ACM8EGE0 A0ACM8EGE0 LOC8051581 PTHR24223:SF474 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN LETHAL(2)03659 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120839690|UniProtKB=A0ACM8EM98 A0ACM8EM98 LOC120839690 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321443|UniProtKB=A0ACM8E1X3 A0ACM8E1X3 LOC115321443 PTHR24404:SF126 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8052425|UniProtKB=A0ACM8E6H9 A0ACM8E6H9 LOC8052425 PTHR12292:SF9 RWD DOMAIN-CONTAINING PROTEIN RWD DOMAIN-CONTAINING PROTEIN 1 cellular response to steroid hormone stimulus#GO:0071383;biological regulation#GO:0065007;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;nuclear receptor-mediated signaling pathway#GO:0141193;cellular process#GO:0009987;signal transduction#GO:0007165;nuclear receptor-mediated steroid hormone signaling pathway#GO:0030518;response to hormone#GO:0009725;intracellular signal transduction#GO:0035556;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;response to steroid hormone#GO:0048545;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;intracellular receptor signaling pathway#GO:0030522;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;steroid hormone receptor signaling pathway#GO:0043401;response to endogenous stimulus#GO:0009719 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115322203|UniProtKB=A0ACM8EJQ4 A0ACM8EJQ4 Fib PTHR10335:SF28 RRNA 2-O-METHYLTRANSFERASE FIBRILLARIN RRNA 2'-O-METHYLTRANSFERASE FIBRILLARIN binding#GO:0005488;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;histone modifying activity#GO:0140993;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;nucleic acid binding#GO:0003676;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;RNA binding#GO:0003723;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;rRNA methyltransferase activity#GO:0008649 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA methylation#GO:0031167;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC121835796|UniProtKB=A0ACM8FVV7 A0ACM8FVV7 LOC121835796 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8025823|UniProtKB=A0ACM8DWE7 A0ACM8DWE7 PTHR12246:SF26 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120847913|UniProtKB=A0ACM8FYW9 A0ACM8FYW9 LOC120847913 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8053191|UniProtKB=A0ACM8DR63 A0ACM8DR63 LOC8053191 PTHR19370:SF184 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE-LIKE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041636|UniProtKB=A0ACM8DKR5 A0ACM8DKR5 Rad9 PTHR15237:SF0 DNA REPAIR PROTEIN RAD9 CELL CYCLE CHECKPOINT CONTROL PROTEIN RAD9 mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;cellular response to radiation#GO:0071478;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;response to ionizing radiation#GO:0010212;signal transduction in response to DNA damage#GO:0042770;cellular response to abiotic stimulus#GO:0071214;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA integrity checkpoint signaling#GO:0031570;response to radiation#GO:0009314;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774 condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 exodeoxyribonuclease#PC00098 IXOSC|EnsemblGenome=LOC115313116|UniProtKB=A0ACM8DSG3 A0ACM8DSG3 LOC115329348 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8029499|UniProtKB=A0ACM8DTR7 A0ACM8DTR7 Cndp2 PTHR43270:SF4 BETA-ALA-HIS DIPEPTIDASE CARNOSINE DIPEPTIDASE 2, ISOFORM A catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8025186|UniProtKB=A0ACM8EBR0 A0ACM8EBR0 LOC8025186 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121836755|UniProtKB=A0ACM8FZW1 A0ACM8FZW1 LOC121836755 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120844442|UniProtKB=A0ACM8EYN9 A0ACM8EYN9 LOC120844442 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8034117|UniProtKB=A0ACM8ECK3 A0ACM8ECK3 MBD-like PTHR12396:SF63 METHYL-CPG BINDING PROTEIN, MBD METHYL-CPG BINDING DOMAIN PROTEIN-LIKE, ISOFORM C negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120843380|UniProtKB=A0ACM8EX25 A0ACM8EX25 LOC120843380 PTHR45632:SF36 LD33804P RING ZINC FINGER-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8043430|UniProtKB=A0ACM8E1U9 A0ACM8E1U9 LOC8043430 PTHR31650:SF1 O-ACYLTRANSFERASE (WSD1-LIKE) FAMILY PROTEIN O-ACYLTRANSFERASE WSD1 C-TERMINAL DOMAIN-CONTAINING PROTEIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;biosynthetic process#GO:0009058;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;primary metabolic process#GO:0044238 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115320082|UniProtKB=A0ACM8DZU6 A0ACM8DZU6 LOC115320082 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8052703|UniProtKB=A0ACM8FRG6 A0ACM8FRG6 LOC8052703 PTHR23252:SF43 INTIMAL THICKNESS RECEPTOR-RELATED GPR180_TMEM145 TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030432|UniProtKB=A0ACM8E3K1 A0ACM8E3K1 rho-7 PTHR43731:SF14 RHOMBOID PROTEASE PRESENILIN-ASSOCIATED RHOMBOID-LIKE PROTEIN, MITOCHONDRIAL hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8035367|UniProtKB=A0ACM8E4X7 A0ACM8E4X7 LOC8035367 PTHR43763:SF4 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 2 protease#PC00190 IXOSC|EnsemblGenome=LOC121836325|UniProtKB=A0ACM8FZJ5 A0ACM8FZJ5 LOC121836325 PTHR21622:SF0 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 localization#GO:0051179;cellular localization#GO:0051641;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;mitochondrial transport#GO:0006839;metabolic process#GO:0008152;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;mitochondrial protein import pathway#GO:7770058;biosynthetic process#GO:0009058 intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115319332|UniProtKB=A0ACM8FGQ6 A0ACM8FGQ6 LOC115319332 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8051126|UniProtKB=A0ACM8EAP3 A0ACM8EAP3 LOC8051126 PTHR22840:SF12 WD REPEAT-CONTAINING PROTEIN 36 WD REPEAT-CONTAINING PROTEIN 36 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC120846961|UniProtKB=A0ACM8F2T3 A0ACM8F2T3 LOC120846961 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8032554|UniProtKB=A0ACM8DSW7 A0ACM8DSW7 Rbbp5 PTHR44040:SF1 RETINOBLASTOMA-BINDING PROTEIN 5 RETINOBLASTOMA-BINDING PROTEIN 5 protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC115320435|UniProtKB=A0ACM8E1S2 A0ACM8E1S2 LOC115320435 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121047463|UniProtKB=A0ACM8G034 A0ACM8G034 LOC121047463 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052407|UniProtKB=A0ACM8DLK2 A0ACM8DLK2 PTHR47979:SF150 DRAB11-RELATED RAB2A, MEMBER RAS ONCOGENE FAMILY ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 small GTPase#PC00208;G-protein#PC00020 PDGF signaling pathway#P00047>Ras#P01154 IXOSC|EnsemblGenome=LOC120848624|UniProtKB=A0ACM8F598 A0ACM8F598 LOC120848624 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;system development#GO:0048731;neurogenesis#GO:0022008;cellular process#GO:0009987;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115331742|UniProtKB=A0ACM8ESW0 A0ACM8ESW0 LOC115331742 PTHR10534:SF2 PYRIDOXAL KINASE PYRIDOXAL KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524;small molecule biosynthetic process#GO:0044283;organophosphate biosynthetic process#GO:0090407 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 kinase#PC00137 Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122;Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244;Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121 IXOSC|EnsemblGenome=LOC115316345|UniProtKB=A0ACM8EXM0 A0ACM8EXM0 LOC115316345 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8031471|UniProtKB=A0ACM8DIA0 A0ACM8DIA0 PTHR12064:SF94 METAL TRANSPORTER CNNM UNEXTENDED PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion homeostasis#GO:0050801;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC115328082|UniProtKB=A0ACM8FBS9 A0ACM8FBS9 LOC115328082 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC120850076|UniProtKB=A0ACM8G305 A0ACM8G305 LOC120850076 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8054038|UniProtKB=A0ACM8DXQ1 A0ACM8DXQ1 LOC8054038 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 deacylase activity#GO:0160215;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8024482|UniProtKB=A0ACM8DIC1 A0ACM8DIC1 LOC8024482 PTHR11662:SF40 SOLUTE CARRIER FAMILY 17 INORGANIC PHOSPHATE COTRANSPORTER-LIKE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121833856|UniProtKB=A0ACM8FPC2 A0ACM8FPC2 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115320314|UniProtKB=A0ACM8E0P3 A0ACM8E0P3 LOC115320314 PTHR23235:SF182 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 2 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115317178|UniProtKB=A0ACM8DXD9 A0ACM8DXD9 LOC115317178 PTHR24366:SF181 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS SLIT HOMOLOG 3 PROTEIN-LIKE immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8053426|UniProtKB=A0ACM8E4N6 A0ACM8E4N6 Ubc4 PTHR24068:SF147 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 K transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Ubiquitin proteasome pathway#P00060>E3#P01490 IXOSC|EnsemblGenome=LOC120846513|UniProtKB=A0ACM8F294 A0ACM8F294 LOC120846513 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8039760|UniProtKB=A0ACM8E667 A0ACM8E667 LOC8039760 PTHR13338:SF4 UPF0240 PROTEIN NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 4 NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8037712|UniProtKB=A0ACM8EIQ0 A0ACM8EIQ0 LOC8037712 PTHR22760:SF1 GLYCOSYLTRANSFERASE DOL-P-MAN:MAN(7)GLCNAC(2)-PP-DOL ALPHA-1,6-MANNOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC121832989|UniProtKB=A0ACM8FWU5 A0ACM8FWU5 LOC121832989 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC121837805|UniProtKB=A0ACM8G572 A0ACM8G572 LOC121837805 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115316021|UniProtKB=A0ACM8DVJ5 A0ACM8DVJ5 PTHR19443:SF16 HEXOKINASE HEXOKINASE-2-RELATED carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hexokinase activity#GO:0004396 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 Glycolysis#P00024>Hexokinase#P00677;Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966 IXOSC|EnsemblGenome=LOC8034645|UniProtKB=A0ACM8DWA1 A0ACM8DWA1 LOC8034645 PTHR11346:SF191 GALECTIN GALECTIN binding#GO:0005488;carbohydrate derivative binding#GO:0097367;carbohydrate binding#GO:0030246 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC115325727|UniProtKB=A0ACM8FTS4 A0ACM8FTS4 LOC115325727 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051546|UniProtKB=A0ACM8EQV2 A0ACM8EQV2 LOC8051546 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;glutathione transferase activity#GO:0004364;antioxidant activity#GO:0016209;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 cellular process#GO:0009987;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8027772|UniProtKB=A0ACM8G5D2 A0ACM8G5D2 LOC8027772 PTHR11003:SF10 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC121833267|UniProtKB=A0ACM8FIT4 A0ACM8FIT4 LOC121833267 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120835992|UniProtKB=A0ACM8F9S7 A0ACM8F9S7 LOC120835992 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8037789|UniProtKB=A0ACM8EBT0 A0ACM8EBT0 Pdk1 PTHR24356:SF449 SERINE/THREONINE-PROTEIN KINASE 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1-RELATED catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;response to hormone#GO:0009725;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;cell surface receptor signaling pathway#GO:0007166;cellular response to insulin stimulus#GO:0032869;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to oxygen-containing compound#GO:1901700;insulin receptor signaling pathway#GO:0008286;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to chemical stimulus#GO:0070887;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>PDK1/2#P04616;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PDK1#P00831;PI3 kinase pathway#P00048>P110ACT#P01177;Ras Pathway#P04393>PDK#P04555;Interleukin signaling pathway#P00036>PDK1/2#P00985;PI3 kinase pathway#P00048>PDK1#P01196;CCKR signaling map#P06959>PDPK1#P07162;PI3 kinase pathway#P00048>PDK1 ACT#P01190;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PDK1/2#P00903;PDGF signaling pathway#P00047>PDK1/2#P01164;p53 pathway feedback loops 2#P04398>PDK1/2#P04656 IXOSC|EnsemblGenome=LOC8031825|UniProtKB=A0ACM8DIU5 A0ACM8DIU5 LOC8031825 PTHR15286:SF1 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN FI07216P scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120844720|UniProtKB=A0ACM8F0H3 A0ACM8F0H3 LOC120844720 PTHR24248:SF215 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 84 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121835351|UniProtKB=A0ACM8FTI5 A0ACM8FTI5 LOC121835351 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837246|UniProtKB=A0ACM8G2Z8 A0ACM8G2Z8 LOC121837246 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026252|UniProtKB=A0ACM8E0Z9 A0ACM8E0Z9 LOC8026252 PTHR15109:SF4 AGAP004327-PA FAM193 C-TERMINAL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313158|UniProtKB=A0ACM8DSQ0 A0ACM8DSQ0 fwe PTHR13314:SF2 CALCIUM CHANNEL FLOWER HOMOLOG CALCIUM CHANNEL FLOWER HOMOLOG monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;endocytosis#GO:0006897;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;synaptic vesicle endocytosis#GO:0048488;import into cell#GO:0098657;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;calcium ion transport#GO:0006816;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 endosome#GO:0005768;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;presynapse#GO:0098793;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8029092|UniProtKB=A0ACM8DY46 A0ACM8DY46 LOC8029092 PTHR10408:SF7 STEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 acyltransferase#PC00042;transferase#PC00220 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 IXOSC|EnsemblGenome=LOC120847544|UniProtKB=A0ACM8G0T8 A0ACM8G0T8 LOC120847544 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833450|UniProtKB=A0ACM8FKU0 A0ACM8FKU0 LOC121833450 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC121833096|UniProtKB=A0ACM8FKC6 A0ACM8FKC6 LOC121833096 PTHR12431:SF14 SORTING NEXIN 17 AND 27 LD15323P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;localization#GO:0051179;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120837759|UniProtKB=A0ACM8G407 A0ACM8G407 LOC120837759 PTHR23235:SF130 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 367 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115309133|UniProtKB=A0ACM8FET2 A0ACM8FET2 LOC115309133 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039944|UniProtKB=A0ACM8FQ15 A0ACM8FQ15 LOC8039944 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE-LIKE transferase#PC00220 IXOSC|EnsemblGenome=LOC8035340|UniProtKB=A0ACM8DME4 A0ACM8DME4 LOC8035340 PTHR11739:SF8 CITRATE SYNTHASE CITRATE SYNTHASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;carbohydrate metabolic process#GO:0005975 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 Pyruvate metabolism#P02772>Citrate Synthetase#P03141;TCA cycle#P00051>Citrate Synthase#P01267 IXOSC|EnsemblGenome=LOC120836043|UniProtKB=A0ACM8F3E3 A0ACM8F3E3 LOC120836043 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115311144|UniProtKB=A0ACM8EFR7 A0ACM8EFR7 LOC115311144 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC8042731|UniProtKB=A0ACM8DSY2 A0ACM8DSY2 LOC8042731 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8053595|UniProtKB=A0ACM8DM63 A0ACM8DM63 LOC8053595 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8027160|UniProtKB=A0ACM8E904 A0ACM8E904 PTHR12891:SF0 DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19 MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027738|UniProtKB=A0ACM8E2N1 A0ACM8E2N1 LOC8027738 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;sodium ion transport#GO:0006814 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120845295|UniProtKB=A0ACM8F1F9 A0ACM8F1F9 LOC120845295 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8052902|UniProtKB=A0ACM8EQ51 A0ACM8EQ51 LOC8052902 PTHR46621:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;snRNA transcription by RNA polymerase III#GO:0042796;transcription by RNA polymerase III#GO:0006383;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;snRNA transcription#GO:0009301 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8031383|UniProtKB=A0ACM8EEA1 A0ACM8EEA1 LOC8031383 PTHR21236:SF1 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF6 Golgi apparatus subcompartment#GO:0098791;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 structural protein#PC00211 IXOSC|EnsemblGenome=LOC120849899|UniProtKB=A0ACM8F8K7 A0ACM8F8K7 LOC120849899 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120837920|UniProtKB=A0ACM8EIJ8 A0ACM8EIJ8 LOC120837920 PTHR20855:SF152 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cellular response to chemical stimulus#GO:0070887;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cell surface receptor signaling pathway#GO:0007166;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8036040|UniProtKB=A0ACM8EY06 A0ACM8EY06 cn PTHR46028:SF2 KYNURENINE 3-MONOOXYGENASE KYNURENINE 3-MONOOXYGENASE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115317565|UniProtKB=A0ACM8EMD4 A0ACM8EMD4 LOC115317565 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313324|UniProtKB=A0ACM8DSP0 A0ACM8DSP0 LOC115313324 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120836421|UniProtKB=A0ACM8EEY9 A0ACM8EEY9 LOC120836421 PTHR12081:SF7 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR EFL-3 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC120847638|UniProtKB=A0ACM8F3K3 A0ACM8F3K3 LOC120847638 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120850314|UniProtKB=A0ACM8F9W9 A0ACM8F9W9 LOC120850314 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120843182|UniProtKB=A0ACM8EVB3 A0ACM8EVB3 LOC120843182 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8051384|UniProtKB=A0ACM8E642 A0ACM8E642 LOC8051384 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033108|UniProtKB=A0ACM8DHF7 A0ACM8DHF7 LOC8033108 PTHR12771:SF51 ENGULFMENT AND CELL MOTILITY LD01482P enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115329188|UniProtKB=A0ACM8E952 A0ACM8E952 LOC115329188 PTHR22775:SF31 SORTING NEXIN SORTING NEXIN-19 small molecule binding#GO:0036094;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053364|UniProtKB=A0ACM8DPT9 A0ACM8DPT9 LOC8053364 PTHR23512:SF13 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 LYSOSOMAL DIPEPTIDE TRANSPORTER MFSD1 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8043281|UniProtKB=A0ACM8EAJ7 A0ACM8EAJ7 LOC8043281 PTHR44825:SF1 FAMILY NOT NAMED DNAJ HOMOLOG SUBFAMILY C MEMBER 4 IXOSC|EnsemblGenome=LOC8051829|UniProtKB=A0ACM8ECQ9 A0ACM8ECQ9 IntS2 PTHR28608:SF1 INTEGRATOR COMPLEX SUBUNIT 2 INTEGRATOR COMPLEX SUBUNIT 2 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;transcription by RNA polymerase II#GO:0006366;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187 integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8028947|UniProtKB=A0ACM8DHE2 A0ACM8DHE2 IntS11 PTHR11203:SF37 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER INTEGRATOR COMPLEX SUBUNIT 11 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8053802|UniProtKB=A0ACM8FHY0 A0ACM8FHY0 LOC8053802 PTHR10983:SF2 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED ACYL-COA:LYSOPHOSPHATIDYLGLYCEROL ACYLTRANSFERASE 1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC121835190|UniProtKB=A0ACM8FTT7 A0ACM8FTT7 LOC121835190 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309471|UniProtKB=A0ACM8F4I3 A0ACM8F4I3 LOC115309471 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314535|UniProtKB=A0ACM8DU21 A0ACM8DU21 LOC115314535 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8030863|UniProtKB=A0ACM8DPZ3 A0ACM8DPZ3 dmpd PTHR13252:SF1 F-BOX ONLY PROTEIN 28 DAMPENED, ISOFORM A transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;metabolic process#GO:0008152;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;protein modification by small protein conjugation or removal#GO:0070647 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115309319|UniProtKB=A0ACM8DNI4 A0ACM8DNI4 LOC115309319 PTHR10625:SF38 HISTONE DEACETYLASE HDAC1-RELATED PROTEIN DEACETYLASE HDAC6 histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component organization#GO:0016043;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC115329209|UniProtKB=A0ACM8E974 A0ACM8E974 LOC115329209 PTHR13902:SF67 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED NUCLEAR RECEPTOR-BINDING PROTEIN HOMOLOG kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115318218|UniProtKB=A0ACM8DYC1 A0ACM8DYC1 LOC115318218 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115330942|UniProtKB=A0ACM8F135 A0ACM8F135 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121837922|UniProtKB=A0ACM8G6Q6 A0ACM8G6Q6 LOC121837922 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8042028|UniProtKB=A0ACM8FYK3 A0ACM8FYK3 LOC8042028 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8033224|UniProtKB=A0ACM8DZ72 A0ACM8DZ72 LOC8033224 PTHR47086:SF4 BTB DOMAIN-CONTAINING PROTEIN BTB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026979|UniProtKB=A0ACM8DIL6 A0ACM8DIL6 LOC8026979 PTHR11214:SF378 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 4 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8050541|UniProtKB=A0ACM8DNN4 A0ACM8DNN4 LOC8050541 PTHR11731:SF193 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED DIPEPTIDYL PEPTIDASE 9 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8041727|UniProtKB=A0ACM8E3U7 A0ACM8E3U7 LOC8041727 PTHR45774:SF3 BTB/POZ DOMAIN-CONTAINING BTB (POZ) DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN-RELATED multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;cellular process#GO:0009987;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120839028|UniProtKB=A0ACM8ELX0 A0ACM8ELX0 LOC120839028 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319419|UniProtKB=A0ACM8DZW5 A0ACM8DZW5 LOC115319419 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835733|UniProtKB=A0ACM8FWN8 A0ACM8FWN8 LOC121835733 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8041685|UniProtKB=A0ACM8E7Z1 A0ACM8E7Z1 rl PTHR24055:SF599 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE ERK-A catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Apoptosis signaling pathway#P00006>MAPK#P00269;FGF signaling pathway#P00021>ERK1-2#P00627;EGF receptor signaling pathway#P00018>ERK1-2#P00543;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;Endothelin signaling pathway#P00019>ERK#P00566;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Parkinson disease#P00049>ERK#P01211;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293 IXOSC|EnsemblGenome=LOC115312279|UniProtKB=A0ACM8DS26 A0ACM8DS26 LOC115312279 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838537|UniProtKB=A0ACM8EJG5 A0ACM8EJG5 LOC120838537 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8035054|UniProtKB=A0ACM8ECF3 A0ACM8ECF3 LOC8035054 PTHR15683:SF8 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B, ISOFORM B intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8029605|UniProtKB=A0ACM8DIH8 A0ACM8DIH8 LOC8029605 PTHR14553:SF1 UNCHARACTERIZED PROTEIN C1ORF50 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 50 IXOSC|EnsemblGenome=LOC115327627|UniProtKB=A0ACM8EVY4 A0ACM8EVY4 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8032450|UniProtKB=A0ACM8DJH9 A0ACM8DJH9 LOC8032450 PTHR12085:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B'' SUBUNIT GAMMA SERINE_THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT RSA-1 cytoskeleton organization#GO:0007010;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cortical cytoskeleton organization#GO:0030865 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC115331366|UniProtKB=A0ACM8EH13 A0ACM8EH13 LOC115331366 PTHR11067:SF9 INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN INOSINE TRIPHOSPHATE PYROPHOSPHATASE hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 organophosphate catabolic process#GO:0046434;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleoside triphosphate metabolic process#GO:0009144;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 nucleotide phosphatase#PC00173 IXOSC|EnsemblGenome=LOC115327108|UniProtKB=A0ACM8EPX2 A0ACM8EPX2 LOC115327108 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC121048061|UniProtKB=A0ACM8FG57 A0ACM8FG57 LOC121048061 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121047849|UniProtKB=A0ACM8FGS2 A0ACM8FGS2 LOC121047849 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115327013|UniProtKB=A0ACM8FFY2 A0ACM8FFY2 LOC115327013 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120836697|UniProtKB=A0ACM8G8A6 A0ACM8G8A6 LOC120836697 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;microbody#GO:0042579 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115321332|UniProtKB=A0ACM8FC19 A0ACM8FC19 LOC115321332 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328890|UniProtKB=A0ACM8ENJ5 A0ACM8ENJ5 LOC115328890 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120839761|UniProtKB=A0ACM8EMH9 A0ACM8EMH9 LOC120839761 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328133|UniProtKB=A0ACM8EID3 A0ACM8EID3 PTHR45632:SF36 LD33804P RING ZINC FINGER-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8033416|UniProtKB=A0ACM8DHW6 A0ACM8DHW6 LOC8033416 PTHR45706:SF1 TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8029493|UniProtKB=A0ACM8E038 A0ACM8E038 Glut1 PTHR23503:SF128 SOLUTE CARRIER FAMILY 2 GLUCOSE TRANSPORTER TYPE 1 sugar transmembrane transporter activity#GO:0051119;carbohydrate transmembrane transporter activity#GO:0015144;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 carbohydrate transport#GO:0008643;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;carbohydrate transmembrane transport#GO:0034219;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8038996|UniProtKB=A0ACM8DMT2 A0ACM8DMT2 LOC8038996 PTHR10502:SF247 ANNEXIN ANNEXIN B10 lipid binding#GO:0008289;phosphatidylserine binding#GO:0001786;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 vesicle#GO:0031982;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC8029730|UniProtKB=A0ACM8DIP1 A0ACM8DIP1 mRpL51 PTHR13409:SF0 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L51 LARGE RIBOSOMAL SUBUNIT PROTEIN ML51 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121838424|UniProtKB=A0ACM8G914 A0ACM8G914 LOC121838424 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038354|UniProtKB=A0ACM8F6P3 A0ACM8F6P3 LOC8038354 PTHR46376:SF1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of Ras protein signal transduction#GO:0046578;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endosome membrane#GO:0010008;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Cul3-RING ubiquitin ligase complex#GO:0031463;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;transferase complex#GO:1990234;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC8051430|UniProtKB=A0ACM8F2V1 A0ACM8F2V1 LOC8051430 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115308876|UniProtKB=A0ACM8DN46 A0ACM8DN46 LOC115308876 PTHR12673:SF267 FACIOGENITAL DYSPLASIA PROTEIN FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 6 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC120850868|UniProtKB=A0ACM8FBX5 A0ACM8FBX5 LOC120850868 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120849945|UniProtKB=A0ACM8G707 A0ACM8G707 LOC120849945 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8040332|UniProtKB=A0ACM8DUX0 A0ACM8DUX0 Alg3 PTHR12646:SF0 NOT56 - RELATED DOL-P-MAN:MAN(5)GLCNAC(2)-PP-DOL ALPHA-1,3-MANNOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120842447|UniProtKB=A0ACM8ETN0 A0ACM8ETN0 LOC120842447 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315564|UniProtKB=A0ACM8FNV4 A0ACM8FNV4 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115316211|UniProtKB=A0ACM8DWC7 A0ACM8DWC7 LOC115316211 PTHR10846:SF77 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 4-RELATED antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115330733|UniProtKB=A0ACM8FE63 A0ACM8FE63 LOC115330733 PTHR24392:SF62 ZINC FINGER PROTEIN PROTEIN CHARLATAN-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115329513|UniProtKB=A0ACM8E9P6 A0ACM8E9P6 LOC115329513 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120837983|UniProtKB=A0ACM8EIW9 A0ACM8EIW9 LOC120837983 PTHR14030:SF29 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 BETA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;chromosome organization#GO:0051276;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;sister chromatid cohesion#GO:0007062;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251;regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;meiotic sister chromatid cohesion#GO:0051177;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;regulation of chromosome segregation#GO:0051983;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121833977|UniProtKB=A0ACM8FMH0 A0ACM8FMH0 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960 trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 signaling receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC8035312|UniProtKB=A0ACM8DWW9 A0ACM8DWW9 LOC8035312 PTHR11202:SF38 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER PROTEIN ENABLED neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cytoskeleton organization#GO:0007010;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;system development#GO:0048731;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;actin filament organization#GO:0007015;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;actin polymerization or depolymerization#GO:0008154 cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115310331|UniProtKB=A0ACM8EMJ7 A0ACM8EMJ7 LOC115310331 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121833001|UniProtKB=A0ACM8G607 A0ACM8G607 LOC121833001 PTHR16172:SF2 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE JET FUEL, ISOFORM A membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120836783|UniProtKB=A0ACM8EFD8 A0ACM8EFD8 LOC120836783 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326583|UniProtKB=A0ACM8F3G3 A0ACM8F3G3 LOC115326583 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120848303|UniProtKB=A0ACM8F5T8 A0ACM8F5T8 LOC120848303 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8053376|UniProtKB=A0ACM8DLS2 A0ACM8DLS2 LOC8053376 PTHR21020:SF0 ZINC FINGER PROTEIN 800 ZINC FINGER PROTEIN 800 IXOSC|EnsemblGenome=LOC120842238|UniProtKB=A0ACM8ETD7 A0ACM8ETD7 LOC120842238 PTHR12101:SF1 POPEYE DOMAIN CONTAINING PROTEIN BVES nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 biological regulation#GO:0065007;heart development#GO:0007507;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;striated muscle cell differentiation#GO:0051146;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;developmental process#GO:0032502;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061;muscle cell differentiation#GO:0042692;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108 bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;sarcolemma#GO:0042383;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296 IXOSC|EnsemblGenome=LOC8050894|UniProtKB=A0ACM8G8C7 A0ACM8G8C7 LOC8050894 PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;proteolysis#GO:0006508;metabolic process#GO:0008152;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120844812|UniProtKB=A0ACM8FR07 A0ACM8FR07 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120836858|UniProtKB=A0ACM8EGM3 A0ACM8EGM3 LOC120836858 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115317636|UniProtKB=A0ACM8DXP3 A0ACM8DXP3 LOC115317636 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8042982|UniProtKB=A0ACM8EE42 A0ACM8EE42 PTHR46538:SF3 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN PROTEIN KINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039252|UniProtKB=A0ACM8E0A9 A0ACM8E0A9 LOC8039252 PTHR45689:SF5 I[[H]] CHANNEL, ISOFORM E I[[H]] CHANNEL, ISOFORM E voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8042772|UniProtKB=A0ACM8ERL0 A0ACM8ERL0 LOC8042772 PTHR24346:SF114 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MAP_MICROTUBULE AFFINITY-REGULATING KINASE 3-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121836341|UniProtKB=A0ACM8FYD8 A0ACM8FYD8 LOC121836341 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;monoatomic cation transmembrane transporter activity#GO:0008324 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121836818|UniProtKB=A0ACM8DNY1 A0ACM8DNY1 LOC8039115 PTHR22891:SF198 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-1 single-stranded RNA binding#GO:0003727;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441 supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC121835176|UniProtKB=A0ACM8FTA1 A0ACM8FTA1 LOC121835176 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8028351|UniProtKB=A0ACM8DJP9 A0ACM8DJP9 LOC8028351 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8025483|UniProtKB=A0ACM8EJZ9 A0ACM8EJZ9 LOC8025483 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121833298|UniProtKB=A0ACM8FK05 A0ACM8FK05 LOC121833298 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115328901|UniProtKB=A0ACM8EH21 A0ACM8EH21 LOC115328901 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120843243|UniProtKB=A0ACM8EVL2 A0ACM8EVL2 LOC120843243 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8040157|UniProtKB=A0ACM8DZV6 A0ACM8DZV6 LOC8040157 PTHR13848:SF56 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE 5 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120836840|UniProtKB=A0ACM8EGW8 A0ACM8EGW8 LOC120836840 PTHR11733:SF224 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-2 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8041504|UniProtKB=A0ACM8DNM4 A0ACM8DNM4 LOC8041504 PTHR11071:SF565 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYLPROLYL ISOMERASE nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8033150|UniProtKB=A0ACM8DHH5 A0ACM8DHH5 LOC8033150 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8036101|UniProtKB=A0ACM8DMZ8 A0ACM8DMZ8 LOC8036101 PTHR45838:SF4 HISTONE-LYSINE-N-METHYLTRANSFERASE 2 KMT2 FAMILY MEMBER HISTONE-LYSINE N-METHYLTRANSFERASE TRITHORAX protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115331569|UniProtKB=A0ACM8EC48 A0ACM8EC48 LOC115331569 PTHR10367:SF9 MRNA-CAPPING ENZYME RNA_RNP COMPLEX-1-INTERACTING PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 mRNA capping factor#PC00145;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115317566|UniProtKB=A0ACM8EHD1 A0ACM8EHD1 LOC115317566 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115325525|UniProtKB=A0ACM8G0W8 A0ACM8G0W8 LOC115325525 PTHR21367:SF1 ARGININE-TRNA-PROTEIN TRANSFERASE 1 ARGINYL-TRNA--PROTEIN TRANSFERASE 1 acyltransferase activity#GO:0016746;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263 IXOSC|EnsemblGenome=LOC120850133|UniProtKB=A0ACM8F832 A0ACM8F832 LOC120850133 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121833386|UniProtKB=A0ACM8FKF4 A0ACM8FKF4 LOC121833386 PTHR14927:SF0 NUCLEOLAR PROTEIN 10 NUCLEOLAR PROTEIN 10 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040 IXOSC|EnsemblGenome=LOC8035875|UniProtKB=A0ACM8DJT0 A0ACM8DJT0 RpL27A PTHR11721:SF3 60S RIBOSOMAL PROTEIN L27A LARGE RIBOSOMAL SUBUNIT PROTEIN UL15 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120838274|UniProtKB=A0ACM8EIW6 A0ACM8EIW6 LOC120838274 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8053561|UniProtKB=A0ACM8E9U7 A0ACM8E9U7 LOC8053561 PTHR12596:SF1 EXPORTIN 4,7-RELATED EXPORTIN-4 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC8030770|UniProtKB=A0ACM8DHG6 A0ACM8DHG6 LOC8030770 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840318|UniProtKB=A0ACM8EPR5 A0ACM8EPR5 LOC120840318 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC115326134|UniProtKB=A0ACM8E677 A0ACM8E677 LOC115326134 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121836649|UniProtKB=A0ACM8FZ07 A0ACM8FZ07 LOC121836649 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8039823|UniProtKB=A0ACM8DR13 A0ACM8DR13 LOC8039823 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC115318287|UniProtKB=A0ACM8FX86 A0ACM8FX86 LOC115318287 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058;cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 microbody#GO:0042579;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121832955|UniProtKB=A0ACM8FWQ7 A0ACM8FWQ7 LOC121832955 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;binding#GO:0005488;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;steroid metabolic process#GO:0008202;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;lipid metabolic process#GO:0006629 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115311827|UniProtKB=A0ACM8DRA7 A0ACM8DRA7 LOC115311827 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115331655|UniProtKB=A0ACM8EDN6 A0ACM8EDN6 LOC115331655 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115330447|UniProtKB=A0ACM8EQA7 A0ACM8EQA7 LOC115330447 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120849761|UniProtKB=A0ACM8F8Q1 A0ACM8F8Q1 LOC120849761 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839881|UniProtKB=A0ACM8ENW2 A0ACM8ENW2 LOC120839881 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120837514|UniProtKB=A0ACM8EIA7 A0ACM8EIA7 LOC120837514 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC8029152|UniProtKB=A0ACM8DZY0 A0ACM8DZY0 LOC8029152 PTHR12128:SF74 DIHYDRODIPICOLINATE SYNTHASE 4-HYDROXY-2-OXOGLUTARATE ALDOLASE, MITOCHONDRIAL carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;aldehyde catabolic process#GO:0046185;monocarboxylic acid catabolic process#GO:0072329;glyoxylate metabolic process#GO:0046487;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 lyase#PC00144 IXOSC|EnsemblGenome=LOC120836739|UniProtKB=A0ACM8EGA2 A0ACM8EGA2 Cad96Ca PTHR24416:SF621 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE KINASE RECEPTOR CAD96CA transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115319058|UniProtKB=A0ACM8DZ94 A0ACM8DZ94 LOC115319058 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8031610|UniProtKB=A0ACM8E1A5 A0ACM8E1A5 psidin PTHR22767:SF3 N-TERMINAL ACETYLTRANSFERASE-RELATED N-ALPHA-ACETYLTRANSFERASE 25, NATB AUXILIARY SUBUNIT enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 protein acetyltransferase complex#GO:0031248;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC120839424|UniProtKB=A0ACM8EL86 A0ACM8EL86 LOC120839424 PTHR11751:SF29 ALANINE AMINOTRANSFERASE ALANINE TRANSAMINASE transaminase#PC00216;transferase#PC00220 IXOSC|EnsemblGenome=LOC8052337|UniProtKB=A0ACM8EVT5 A0ACM8EVT5 LOC8052337 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120842834|UniProtKB=A0ACM8EUL2 A0ACM8EUL2 LOC120842834 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8039686|UniProtKB=A0ACM8E2I7 A0ACM8E2I7 LOC8039686 PTHR12988:SF6 SPHINGOMYELIN PHOSPHODIESTERASE 4 SPHINGOMYELIN PHOSPHODIESTERASE 4 phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 glycerophospholipid catabolic process#GO:0046475;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate catabolic process#GO:0046434;ceramide metabolic process#GO:0006672;glycerolipid catabolic process#GO:0046503;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644;sphingolipid catabolic process#GO:0030149;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC115312028|UniProtKB=A0ACM8DRT9 A0ACM8DRT9 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039083|UniProtKB=A0ACM8E4N8 A0ACM8E4N8 LOC8039083 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8023829|UniProtKB=A0ACM8FZN8 A0ACM8FZN8 LOC8023829 PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 catabolic process#GO:0009056;primary metabolic process#GO:0044238;peptide catabolic process#GO:0043171;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8023960|UniProtKB=A0ACM8DX22 A0ACM8DX22 LOC8023960 PTHR16243:SF2 BTG3-ASSOCIATED NUCLEAR PROTEIN BANP PROTEIN BANP IXOSC|EnsemblGenome=LOC121048209|UniProtKB=A0ACM8FHW8 A0ACM8FHW8 LOC121048209 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8037735|UniProtKB=A0ACM8DMD2 A0ACM8DMD2 LOC8037735 PTHR23352:SF2 NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN-1 NPDC-1 PROTEIN NEURAL PROLIFERATION DIFFERENTIATION AND CONTROL PROTEIN 1 IXOSC|EnsemblGenome=LOC115324104|UniProtKB=A0ACM8EZU8 A0ACM8EZU8 LOC115324104 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8037277|UniProtKB=A0ACM8FTL6 A0ACM8FTL6 LOC8037277 PTHR18063:SF6 NF-E2 INDUCIBLE PROTEIN UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 IXOSC|EnsemblGenome=LOC120847831|UniProtKB=A0ACM8F4M7 A0ACM8F4M7 LOC120847831 PTHR46948:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P38 RIBONUCLEASE P PROTEIN SUBUNIT P38 endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC115318151|UniProtKB=A0ACM8EQE4 A0ACM8EQE4 LOC115318151 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC115332190|UniProtKB=A0ACM8ECZ8 A0ACM8ECZ8 LOC115332190 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115329896|UniProtKB=A0ACM8FAS6 A0ACM8FAS6 LOC115329896 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115325421|UniProtKB=A0ACM8E5K7 A0ACM8E5K7 LOC115325421 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8026720|UniProtKB=A0ACM8DTL9 A0ACM8DTL9 stmA PTHR12444:SF8 PROTEIN EFR3 HOMOLOG CMP44E PROTEIN EFR3 HOMOLOG CMP44E protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC115320310|UniProtKB=A0ACM8ETF8 A0ACM8ETF8 LOC115320310 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120849235|UniProtKB=A0ACM8F8A6 A0ACM8F8A6 LOC120849235 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120836119|UniProtKB=A0ACM8FUV6 A0ACM8FUV6 LOC120836119 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120838338|UniProtKB=A0ACM8FP42 A0ACM8FP42 LOC120838338 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024484|UniProtKB=A0ACM8DID4 A0ACM8DID4 U2A PTHR10552:SF11 U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A U2 SMALL NUCLEAR RIBONUCLEOPROTEIN A' nucleic acid binding#GO:0003676;binding#GO:0005488;snRNA binding#GO:0017069;RNA binding#GO:0003723 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;U2 snRNP#GO:0005686;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8041528|UniProtKB=A0ACM8E0Z8 A0ACM8E0Z8 LOC8041528 PTHR11629:SF114 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;protein binding#GO:0005515;monoatomic cation transmembrane transporter activity#GO:0008324;binding#GO:0005488;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;proton transmembrane transport#GO:1902600;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC120851181|UniProtKB=A0ACM8FCB4 A0ACM8FCB4 LOC120851181 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8034360|UniProtKB=A0ACM8DPF3 A0ACM8DPF3 PTHR18034:SF3 CELL CYCLE CONTROL PROTEIN CWF22-RELATED PRE-MRNA-SPLICING FACTOR CWC22 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115317303|UniProtKB=A0ACM8ELE0 A0ACM8ELE0 LOC115317303 PTHR24393:SF175 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120838199|UniProtKB=A0ACM8EKB0 A0ACM8EKB0 MED4 PTHR13208:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 4 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC115329204|UniProtKB=A0ACM8E992 A0ACM8E992 LOC115329204 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED IXOSC|EnsemblGenome=LOC8026415|UniProtKB=A0ACM8EA31 A0ACM8EA31 Dsp1 PTHR48112:SF44 HIGH MOBILITY GROUP PROTEIN DSP1 HIGH MOBILITY GROUP PROTEIN DSP1 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 IXOSC|EnsemblGenome=LOC8030775|UniProtKB=A0ACM8DHI0 A0ACM8DHI0 LOC8030775 PTHR19282:SF565 TETRASPANIN TETRASPANIN-14 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8052185|UniProtKB=A0ACM8DM12 A0ACM8DM12 LOC8052185 PTHR22942:SF30 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN DMC1 HOMOLOG ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;double-strand break repair#GO:0006302;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;protein-containing complex assembly#GO:0065003;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;reproductive process#GO:0022414;homologous recombination#GO:0035825;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;organelle fission#GO:0048285;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;meiosis I cell cycle process#GO:0061982 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;condensed nuclear chromosome#GO:0000794;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8024601|UniProtKB=A0ACM8EMD2 A0ACM8EMD2 LOC8024601 PTHR12127:SF25 MUCOLIPIN SD02261P monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ligand-gated calcium channel activity#GO:0099604;gated channel activity#GO:0022836 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8030726|UniProtKB=A0ACM8DR55 A0ACM8DR55 LOC8030726 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC120838299|UniProtKB=A0ACM8EK94 A0ACM8EK94 LOC120838299 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325931|UniProtKB=A0ACM8FZL9 A0ACM8FZL9 LOC115325931 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8040282|UniProtKB=A0ACM8E0S3 A0ACM8E0S3 128up PTHR43127:SF1 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 1 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166 cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115316339|UniProtKB=A0ACM8DVU9 A0ACM8DVU9 LOC115319862 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115331153|UniProtKB=A0ACM8EBR5 A0ACM8EBR5 PTHR10334:SF548 CYSTEINE-RICH SECRETORY PROTEIN-RELATED CYSTEINE-RICH SECRETORY PROTEIN 2-LIKE PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC115326997|UniProtKB=A0ACM8FQ01 A0ACM8FQ01 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025953|UniProtKB=A0ACM8FE72 A0ACM8FE72 LOC8025953 PTHR44927:SF2 FK506-BINDING PROTEIN 15 PEPTIDYLPROLYL ISOMERASE IXOSC|EnsemblGenome=LOC120841084|UniProtKB=A0ACM8ERW8 A0ACM8ERW8 LOC120841084 PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;catabolic process#GO:0009056;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115321584|UniProtKB=A0ACM8EGW3 A0ACM8EGW3 LOC115321584 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115315540|UniProtKB=A0ACM8EL71 A0ACM8EL71 LOC115315540 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8033098|UniProtKB=A0ACM8ECJ9 A0ACM8ECJ9 LOC8033098 PTHR11003:SF356 POTASSIUM CHANNEL, SUBFAMILY K RE21922P channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215 metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC120848781|UniProtKB=A0ACM8FQN1 A0ACM8FQN1 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850451|UniProtKB=A0ACM8FV15 A0ACM8FV15 LOC120850451 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023093|UniProtKB=A0ACM8F134 A0ACM8F134 LOC8023093 PTHR46393:SF7 SUSHI DOMAIN-CONTAINING PROTEIN C3_C5 CONVERTASE IXOSC|EnsemblGenome=LOC115308189|UniProtKB=A0ACM8E3L3 A0ACM8E3L3 LOC115308189 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 IXOSC|EnsemblGenome=LOC120842007|UniProtKB=A0ACM8ESU6 A0ACM8ESU6 LOC120842007 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038964|UniProtKB=A0ACM8E0D2 A0ACM8E0D2 LOC8038964 PTHR46560:SF11 CYPHER, ISOFORM B GH09980P anatomical structure development#GO:0048856;cell morphogenesis#GO:0000902;developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC120839093|UniProtKB=A0ACM8EMC1 A0ACM8EMC1 LOC120839093 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115317686|UniProtKB=A0ACM8EIR6 A0ACM8EIR6 LOC115317686 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8038632|UniProtKB=A0ACM8DK51 A0ACM8DK51 LOC8038632 PTHR21213:SF0 GEO09665P1-RELATED ZINC FINGER PROTEIN 706 IXOSC|EnsemblGenome=LOC121838545|UniProtKB=A0ACM8G8M7 A0ACM8G8M7 LOC121838545 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8024047|UniProtKB=A0ACM8DHW2 A0ACM8DHW2 LOC8024047 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8036788|UniProtKB=A0ACM8EFB9 A0ACM8EFB9 LOC8036788 PTHR14089:SF6 PRE-MRNA-SPLICING FACTOR RBM22 PRE-MRNA-SPLICING FACTOR RBM22 binding#GO:0005488;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8040733|UniProtKB=A0ACM8FIG9 A0ACM8FIG9 LOC8040733 PTHR46711:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 [HISTONE H3]-LYSINE(36) N-TRIMETHYLTRANSFERASE histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC120837975|UniProtKB=A0ACM8EJQ3 A0ACM8EJQ3 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8051728|UniProtKB=A0ACM8FX71 A0ACM8FX71 LOC8051728 PTHR43440:SF1 UREASE UREASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8038604|UniProtKB=A0ACM8DXG6 A0ACM8DXG6 LOC8038604 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120839370|UniProtKB=A0ACM8ELZ2 A0ACM8ELZ2 Sec61alpha PTHR10906:SF1 SECY/SEC61-ALPHA FAMILY MEMBER DSEC61ALPHA protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;transmembrane protein transporter activity#GO:0008320;ribonucleoprotein complex binding#GO:0043021;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;binding#GO:0005488 protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;localization within membrane#GO:0051668;protein transport#GO:0015031;post-translational protein targeting to membrane, translocation#GO:0031204;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization to endoplasmic reticulum#GO:0072599;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;rough endoplasmic reticulum#GO:0005791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 transporter#PC00227 IXOSC|EnsemblGenome=LOC115317350|UniProtKB=A0ACM8DX28 A0ACM8DX28 LOC115317350 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317827|UniProtKB=A0ACM8DXX2 A0ACM8DXX2 mRpL35 PTHR15909:SF0 39S RIBOSOMAL PROTEIN L35, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL35M intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8025869|UniProtKB=A0ACM8DGL5 A0ACM8DGL5 Clic PTHR43920:SF11 CHLORIDE INTRACELLULAR CHANNEL, ISOFORM A CHLORIDE INTRACELLULAR CHANNEL CLIC channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic anion transport#GO:0006820 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cytoplasm#GO:0005737;plasma membrane#GO:0005886;apical part of cell#GO:0045177;intracellular anatomical structure#GO:0005622 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC120840264|UniProtKB=A0ACM8EN15 A0ACM8EN15 LOC120840264 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8041049|UniProtKB=A0ACM8E027 A0ACM8E027 PTHR45806:SF1 SYNAPTOBREVIN HOMOLOG YKT6 SYNAPTOBREVIN HOMOLOG YKT6 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152;membrane organization#GO:0061024;vacuole fusion, non-autophagic#GO:0042144;macroautophagy#GO:0016236;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;vacuole fusion#GO:0097576;vesicle fusion#GO:0006906;catabolic process#GO:0009056;intra-Golgi vesicle-mediated transport#GO:0006891;cellular component organization#GO:0016043 organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794 IXOSC|EnsemblGenome=LOC8027258|UniProtKB=A0ACM8EBJ5 A0ACM8EBJ5 LOC8027258 PTHR12277:SF72 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN BAT5L PROTEIN glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;modified amino acid metabolic process#GO:0006575;organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate metabolic process#GO:0019637;acylglycerol catabolic process#GO:0046464;glycerophospholipid catabolic process#GO:0046475;neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115322491|UniProtKB=A0ACM8ENF1 A0ACM8ENF1 LOC115322491 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8039336|UniProtKB=A0ACM8EDE8 A0ACM8EDE8 LOC8039336 PTHR13261:SF0 BRCA2 AND CDKN1A INTERACTING PROTEIN BRCA2 AND CDKN1A-INTERACTING PROTEIN enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule anchoring#GO:0034453;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of protein modification process#GO:0031399;mitotic cell cycle process#GO:1903047 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;spindle pole#GO:0000922 IXOSC|EnsemblGenome=LOC121837798|UniProtKB=A0ACM8G579 A0ACM8G579 LOC121837798 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC120839946|UniProtKB=A0ACM8EP14 A0ACM8EP14 LOC120839946 PTHR42722:SF1 LEUCINE DEHYDROGENASE VALINE DEHYDROGENASE oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8039805|UniProtKB=A0ACM8FL96 A0ACM8FL96 LOC8039805 PTHR24120:SF4 GH07239P GH07239P IXOSC|EnsemblGenome=LOC8052406|UniProtKB=A0ACM8ECN6 A0ACM8ECN6 PTHR13318:SF275 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 13 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC115329905|UniProtKB=A0ACM8EB13 A0ACM8EB13 carmine PTHR10529:SF340 AP COMPLEX SUBUNIT MU CARMINE, ISOFORM A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 intracellular transport#GO:0046907;vacuolar transport#GO:0007034;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;AP-type membrane coat adaptor complex#GO:0030119;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120842535|UniProtKB=A0ACM8EU09 A0ACM8EU09 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8026953|UniProtKB=A0ACM8E3X6 A0ACM8E3X6 LOC8026953 PTHR13264:SF5 GCIP-INTERACTING PROTEIN P29 PRE-MRNA-SPLICING FACTOR SYF2 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC120848149|UniProtKB=A0ACM8F4G4 A0ACM8F4G4 LOC120848149 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8041422|UniProtKB=A0ACM8DKP7 A0ACM8DKP7 LOC8041422 PTHR12101:SF30 POPEYE DOMAIN CONTAINING PROTEIN POPEYE DOMAIN-CONTAINING PROTEIN 3-LIKE PROTEIN nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 developmental process#GO:0032502;striated muscle cell differentiation#GO:0051146;regulation of membrane potential#GO:0042391;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154 anchoring junction#GO:0070161;sarcolemma#GO:0042383;cell junction#GO:0030054;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120842994|UniProtKB=A0ACM8EV05 A0ACM8EV05 PTHR11079:SF156 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE-34 DEAMINASE REGULATORY SUBUNIT ADAT3 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 IXOSC|EnsemblGenome=LOC8035437|UniProtKB=A0ACM8F043 A0ACM8F043 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115308347|UniProtKB=A0ACM8FA68 A0ACM8FA68 LOC115308347 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8027263|UniProtKB=A0ACM8DW22 A0ACM8DW22 Gint3 PTHR23153:SF38 UBX-RELATED UBX DOMAIN-CONTAINING PROTEIN 6 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8050627|UniProtKB=A0ACM8EGN5 A0ACM8EGN5 DAT PTHR11616:SF341 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT DOPAMINE TRANSPORTER secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;organic hydroxy compound transport#GO:0015850;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;synaptic transmission, dopaminergic#GO:0001963;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization in cell#GO:0051649;synaptic signaling#GO:0099536;nitrogen compound transport#GO:0071705;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;neurotransmitter transport#GO:0006836;cell-cell signaling#GO:0007267;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;import into cell#GO:0098657 axon#GO:0030424;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cell body#GO:0044297;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;presynaptic membrane#GO:0042734;membrane#GO:0016020;presynapse#GO:0098793;neuron projection#GO:0043005;cell periphery#GO:0071944 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115315327|UniProtKB=A0ACM8DV73 A0ACM8DV73 LOC115315327 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8026286|UniProtKB=A0ACM8EDR1 A0ACM8EDR1 LOC8026286 PTHR12151:SF5 ELECTRON TRANSPORT PROTIN SCO1/SENC FAMILY MEMBER AT19154P protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8028705|UniProtKB=A0ACM8EW85 A0ACM8EW85 LOC8028705 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121834294|UniProtKB=A0ACM8FQS6 A0ACM8FQS6 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041555|UniProtKB=A0ACM8DKR1 A0ACM8DKR1 ND-24 PTHR10371:SF3 NADH DEHYDROGENASE UBIQUINONE FLAVOPROTEIN 2, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 2, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176;dehydrogenase#PC00092 Parkinson disease#P00049>Complex I#P01237 IXOSC|EnsemblGenome=LOC120842207|UniProtKB=A0ACM8ETB9 A0ACM8ETB9 LOC120842207 PTHR47501:SF5 TRANSPOSASE-RELATED BED-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8029727|UniProtKB=A0ACM8DIP8 A0ACM8DIP8 LOC8029727 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120836570|UniProtKB=A0ACM8EFF0 A0ACM8EFF0 LOC120836570 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842830|UniProtKB=A0ACM8EUP7 A0ACM8EUP7 LOC120842830 PTHR24058:SF136 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 4 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121836001|UniProtKB=A0ACM8FXW7 A0ACM8FXW7 LOC121836001 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8051429|UniProtKB=A0ACM8FZP0 A0ACM8FZP0 LOC8051429 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115321311|UniProtKB=A0ACM8EUE5 A0ACM8EUE5 LOC115321311 PTHR16515:SF77 PR DOMAIN ZINC FINGER PROTEIN SUBFAMILY NOT NAMED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121837857|UniProtKB=A0ACM8G5F1 A0ACM8G5F1 LOC121837857 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836005|UniProtKB=A0ACM8FJJ5 A0ACM8FJJ5 LOC120836005 PTHR45627:SF16 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016 signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cyclic nucleotide biosynthetic process#GO:0009190;G protein-coupled receptor signaling pathway#GO:0007186;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 adenylate cyclase#PC00043 IXOSC|EnsemblGenome=LOC120840108|UniProtKB=A0ACM8ENE9 A0ACM8ENE9 LOC120840108 PTHR12606:SF141 SENTRIN/SUMO-SPECIFIC PROTEASE GH15225P-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protease#PC00190 IXOSC|EnsemblGenome=LOC8024834|UniProtKB=A0ACM8EBN3 A0ACM8EBN3 LOC8024834 PTHR23176:SF145 RHO/RAC/CDC GTPASE-ACTIVATING PROTEIN RHO GTPASE ACTIVATING PROTEIN AT 16F, ISOFORM E enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 IXOSC|EnsemblGenome=LOC115331991|UniProtKB=A0ACM8ECY3 A0ACM8ECY3 LOC115331991 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8038256|UniProtKB=A0ACM8EYJ8 A0ACM8EYJ8 LOC8038256 PTHR13603:SF1 TRANSMEMBRANE PROTEIN 186 TRANSMEMBRANE PROTEIN 186 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120841204|UniProtKB=A0ACM8ES70 A0ACM8ES70 LOC120841204 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC120840800|UniProtKB=A0ACM8ER78 A0ACM8ER78 LOC120840800 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8042176|UniProtKB=A0ACM8DWU9 A0ACM8DWU9 LOC8042176 PTHR21432:SF21 ACETYL-COA HYDROLASE-RELATED GM14349P mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121 Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807 IXOSC|EnsemblGenome=LOC115312744|UniProtKB=A0ACM8EXD8 A0ACM8EXD8 LOC115312744 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311602|UniProtKB=A0ACM8DQX7 A0ACM8DQX7 LOC115311602 PTHR43245:SF51 BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA HYDROXY-DELTA-5-STEROID DEHYDROGENASE, 3 BETA- AND STEROID DELTA-ISOMERASE 1 IXOSC|EnsemblGenome=LOC8024358|UniProtKB=A0ACM8DI67 A0ACM8DI67 LOC8024358 PTHR24419:SF39 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE PELLE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;response to cytokine#GO:0034097;cell surface receptor signaling pathway#GO:0007166;response to lipopolysaccharide#GO:0032496;response to molecule of bacterial origin#GO:0002237;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;biological process involved in interspecies interaction between organisms#GO:0044419;signaling#GO:0023052;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to peptide#GO:1901652;response to other organism#GO:0051707;biological regulation#GO:0065007;response to external stimulus#GO:0009605;cellular response to molecule of bacterial origin#GO:0071219;cellular response to stimulus#GO:0051716;cellular response to biotic stimulus#GO:0071216;cell cycle#GO:0007049;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cytokine-mediated signaling pathway#GO:0019221;lipopolysaccharide-mediated signaling pathway#GO:0031663;response to bacterium#GO:0009617;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Toll pathway-drosophila#P06217>PLL#P06338 IXOSC|EnsemblGenome=LOC8028744|UniProtKB=A0ACM8DN85 A0ACM8DN85 LOC8028744 PTHR48020:SF55 PROTON MYO-INOSITOL COTRANSPORTER PROTON MYO-INOSITOL COTRANSPORTER solute:proton symporter activity#GO:0015295;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;organic hydroxy compound transport#GO:0015850 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115328762|UniProtKB=A0ACM8ERS7 A0ACM8ERS7 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029239|UniProtKB=A0ACM8EA85 A0ACM8EA85 LOC8029239 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine-type peptidase activity#GO:0008236 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8029183|UniProtKB=A0ACM8DMB2 A0ACM8DMB2 LOC8029183 PTHR10680:SF40 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYL-ALPHA-HYDROXYGLYCINE ALPHA-AMIDATING LYASE 2 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115330581|UniProtKB=A0ACM8F9G1 A0ACM8F9G1 LOC115330581 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G PROTEIN-COUPLED RECEPTOR 4, ISOFORM C peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;hormone-mediated signaling pathway#GO:0009755;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115324017|UniProtKB=A0ACM8F5U5 A0ACM8F5U5 LOC115324017 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8042657|UniProtKB=A0ACM8EAC8 A0ACM8EAC8 LOC8042657 PTHR12922:SF10 UBIQUINONE BIOSYNTHESIS PROTEIN UBIQUINONE BIOSYNTHESIS PROTEIN COQ4 HOMOLOG, MITOCHONDRIAL lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120848179|UniProtKB=A0ACM8G7I5 A0ACM8G7I5 LOC120848179 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121833089|UniProtKB=A0ACM8FJG1 A0ACM8FJG1 LOC121833089 PTHR11588:SF13 TUBULIN TUBULIN EPSILON CHAIN guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;tubulin#PC00228 IXOSC|EnsemblGenome=LOC115310866|UniProtKB=A0ACM8FDV2 A0ACM8FDV2 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8029805|UniProtKB=A0ACM8EEB4 A0ACM8EEB4 LOC8029805 PTHR21324:SF2 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED CWH43-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121833676|UniProtKB=A0ACM8FN33 A0ACM8FN33 LOC121833676 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024016|UniProtKB=A0ACM8ES54 A0ACM8ES54 LOC8024016 PTHR10516:SF443 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FK506-BINDING PROTEIN 59 catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity#GO:0003824 protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 IXOSC|EnsemblGenome=LOC120849478|UniProtKB=A0ACM8F7V6 A0ACM8F7V6 LOC120849478 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121048642|UniProtKB=A0ACM8FHJ4 A0ACM8FHJ4 LOC121048642 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313580|UniProtKB=A0ACM8FEY4 A0ACM8FEY4 LOC115313580 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121837230|UniProtKB=A0ACM8G3V0 A0ACM8G3V0 LOC121837230 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC8035739|UniProtKB=A0ACM8F148 A0ACM8F148 LOC8035739 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC8027246|UniProtKB=A0ACM8F3S7 A0ACM8F3S7 LOC8027246 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120838578|UniProtKB=A0ACM8EKA1 A0ACM8EKA1 PTHR47333:SF8 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN FIBULIN-5 IXOSC|EnsemblGenome=LOC120840952|UniProtKB=A0ACM8EQQ5 A0ACM8EQQ5 LOC120840952 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314061|UniProtKB=A0ACM8FVJ3 A0ACM8FVJ3 LOC115314061 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC8027105|UniProtKB=A0ACM8E9I9 A0ACM8E9I9 MetRS PTHR45765:SF1 METHIONINE--TRNA LIGASE METHIONINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;catalytic complex#GO:1902494 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC121835822|UniProtKB=A0ACM8FV93 A0ACM8FV93 LOC121835822 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8025081|UniProtKB=A0ACM8G4S6 A0ACM8G4S6 LOC8025081 PTHR45712:SF40 AGAP008170-PA LRRCT DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835820|UniProtKB=A0ACM8FVY8 A0ACM8FVY8 LOC121835820 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121837997|UniProtKB=A0ACM8G745 A0ACM8G745 LOC121837997 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8028474|UniProtKB=A0ACM8DMD6 A0ACM8DMD6 Sar1 PTHR45684:SF2 RE74312P SMALL MONOMERIC GTPASE hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 COPII-coated vesicle budding#GO:0090114;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982 IXOSC|EnsemblGenome=LOC115330915|UniProtKB=A0ACM8F9T7 A0ACM8F9T7 LOC115330915 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8044029|UniProtKB=A0ACM8EPK1 A0ACM8EPK1 LOC8044029 PTHR46187:SF3 ALKALINE CERAMIDASE 3 ALKALINE CERAMIDASE 3 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingoid biosynthetic process#GO:0046520;primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120846545|UniProtKB=A0ACM8F2M9 A0ACM8F2M9 LOC120846545 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8053480|UniProtKB=A0ACM8FAI8 A0ACM8FAI8 cN-IIIB PTHR13045:SF0 5'-NUCLEOTIDASE 7-METHYLGUANOSINE PHOSPHATE-SPECIFIC 5'-NUCLEOTIDASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;esterase#PC00097 IXOSC|EnsemblGenome=LOC8033141|UniProtKB=A0ACM8DHG1 A0ACM8DHG1 LOC8033141 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8043477|UniProtKB=A0ACM8DL29 A0ACM8DL29 LOC8043477 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115315567|UniProtKB=A0ACM8DV03 A0ACM8DV03 Rpt1 PTHR23073:SF13 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 7 isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 proteasome complex#GO:0000502;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC8026940|UniProtKB=A0ACM8EGI8 A0ACM8EGI8 LOC8026940 PTHR10623:SF6 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER EB1, ISOFORM F-RELATED tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017;protein binding#GO:0005515 organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein localization to cytoskeleton#GO:0044380;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;chromosome segregation#GO:0007059;intracellular protein localization#GO:0008104;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698 intracellular organelle#GO:0043229;microtubule#GO:0005874;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoplasmic microtubule#GO:0005881;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC121838157|UniProtKB=A0ACM8G6M1 A0ACM8G6M1 LOC121838157 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121046760|UniProtKB=A0ACM8FEM5 A0ACM8FEM5 LOC121046760 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8038898|UniProtKB=A0ACM8EH75 A0ACM8EH75 LOC8038898 PTHR19871:SF28 BETA TRANSDUCIN-RELATED PROTEIN AAA+ ATPASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038542|UniProtKB=A0ACM8E664 A0ACM8E664 LOC8038542 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC8034786|UniProtKB=A0ACM8EH11 A0ACM8EH11 LOC8034786 PTHR42884:SF13 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 2 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;peptide hormone processing#GO:0016486;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;hormone metabolic process#GO:0042445;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;neuron projection#GO:0043005;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 IXOSC|EnsemblGenome=LOC8028408|UniProtKB=A0ACM8DJQ5 A0ACM8DJQ5 NKAIN PTHR13084:SF6 T-CELL LYMPHOMA BREAKPOINT-ASSOCIATED TARGET 1-RELATED SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA-1-INTERACTING PROTEIN regulation of transport#GO:0051049;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8053961|UniProtKB=A0ACM8DU33 A0ACM8DU33 LOC8053961 PTHR14898:SF0 ENHANCER OF POLYCOMB ENHANCER OF POLYCOMB-LIKE PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115314428|UniProtKB=A0ACM8EUY4 A0ACM8EUY4 PTHR33776:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839644|UniProtKB=A0ACM8EM53 A0ACM8EM53 LOC120839644 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8050430|UniProtKB=A0ACM8DYU0 A0ACM8DYU0 LOC8050430 PTHR48021:SF1 FAMILY NOT NAMED MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8036583|UniProtKB=A0ACM8EBB4 A0ACM8EBB4 Grip75 PTHR19302:SF27 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 4 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC120850756|UniProtKB=A0ACM8FNX5 A0ACM8FNX5 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120836611|UniProtKB=A0ACM8G765 A0ACM8G765 LOC120836611 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121046940|UniProtKB=A0ACM8FF68 A0ACM8FF68 LOC121046940 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115314366|UniProtKB=A0ACM8G7B4 A0ACM8G7B4 LOC115314366 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8042445|UniProtKB=A0ACM8DUH8 A0ACM8DUH8 Arl2 PTHR45697:SF2 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2 ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 IXOSC|EnsemblGenome=LOC120845956|UniProtKB=A0ACM8F0G0 A0ACM8F0G0 LOC120845956 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042030|UniProtKB=A0ACM8DY64 A0ACM8DY64 LOC8042030 PTHR48094:SF28 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED PROTEIN DJ-1ALPHA-RELATED hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;response to oxidative stress#GO:0006979;monocarboxylic acid biosynthetic process#GO:0072330;response to stress#GO:0006950;alcohol biosynthetic process#GO:0046165;cellular response to oxygen-containing compound#GO:1901701;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;response to chemical#GO:0042221;detoxification#GO:0098754;biosynthetic process#GO:0009058;cellular response to toxic substance#GO:0097237;aldehyde catabolic process#GO:0046185;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;monocarboxylic acid metabolic process#GO:0032787;cellular detoxification of aldehyde#GO:0110095;carboxylic acid metabolic process#GO:0019752;ketone metabolic process#GO:0042180;carboxylic acid biosynthetic process#GO:0046394;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;small molecule catabolic process#GO:0044282 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8040158|UniProtKB=A0ACM8DKI7 A0ACM8DKI7 LOC8040158 PTHR47958:SF26 ATP-DEPENDENT RNA HELICASE DBP3 EUKARYOTIC INITIATION FACTOR 4A-III RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 membraneless organelle#GO:0043228;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC120847891|UniProtKB=A0ACM8F543 A0ACM8F543 LOC120847891 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8030690|UniProtKB=A0ACM8DHC9 A0ACM8DHC9 LOC8030690 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8025701|UniProtKB=A0ACM8DJG6 A0ACM8DJG6 mRpL15 PTHR12934:SF15 50S RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN UL15M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8040340|UniProtKB=A0ACM8FZT2 A0ACM8FZT2 Atg5 PTHR13040:SF2 AUTOPHAGY PROTEIN 5 AUTOPHAGY PROTEIN 5 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787 autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;response to stress#GO:0006950;response to nutrient levels#GO:0031667;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization#GO:0016043;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727 phagophore assembly site#GO:0000407;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC115318281|UniProtKB=A0ACM8EY82 A0ACM8EY82 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8050479|UniProtKB=A0ACM8DLC8 A0ACM8DLC8 LOC8050479 PTHR11447:SF16 CELLULAR TUMOR ANTIGEN P53 P53, ISOFORM B transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;signaling#GO:0023052;signal transduction by p53 class mediator#GO:0072331;cellular response to stress#GO:0033554;intrinsic apoptotic signaling pathway#GO:0097193;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of apoptotic process#GO:0042981;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;DNA damage response#GO:0006974;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 P53-like transcription factor#PC00253;gene-specific transcriptional regulator#PC00264 Huntington disease#P00029>p53#P00797 IXOSC|EnsemblGenome=LOC8053552|UniProtKB=A0ACM8EC23 A0ACM8EC23 hyd PTHR46276:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR5 E3 UBIQUITIN-PROTEIN LIGASE UBR5 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;regulation of signaling#GO:0023051;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;regulation of signal transduction#GO:0009966;post-translational protein modification#GO:0043687 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 Hedgehog signaling pathway#P00025>Ubiquitin ligase#P00693 IXOSC|EnsemblGenome=LOC120840973|UniProtKB=A0ACM8EQJ6 A0ACM8EQJ6 LOC120840973 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120844450|UniProtKB=A0ACM8FV02 A0ACM8FV02 LOC120844450 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846486|UniProtKB=A0ACM8F1P1 A0ACM8F1P1 LOC120846486 PTHR13336:SF3 OVARIAN CARCINOMA IMMUNOREACTIVE ANTIGEN OCIA DOMAIN-CONTAINING PROTEIN 1 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8037278|UniProtKB=A0ACM8DI10 A0ACM8DI10 mRpL28 PTHR13528:SF3 39S RIBOSOMAL PROTEIN L28, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN BL28M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8036006|UniProtKB=A0ACM8F393 A0ACM8F393 LOC8036006 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599;glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC8040372|UniProtKB=A0ACM8EXD0 A0ACM8EXD0 LOC8040372 PTHR12187:SF11 AGAP000124-PA PHOSPHATIDYLINOSITOL-3,4-BISPHOSPHATE 4-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8036717|UniProtKB=A0ACM8EC83 A0ACM8EC83 LOC8036717 PTHR13382:SF85 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B SUBFAMILY NOT NAMED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC121836092|UniProtKB=A0ACM8FX96 A0ACM8FX96 LOC121836092 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8034983|UniProtKB=A0ACM8E435 A0ACM8E435 LOC8034983 PTHR47969:SF35 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED KINESIN-LIKE PROTEIN microtubule binding motor protein#PC00156;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8052411|UniProtKB=A0ACM8FXY5 A0ACM8FXY5 LOC8052411 PTHR10677:SF3 UBIQUILIN FI07626P-RELATED binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;protein binding#GO:0005515 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115312772|UniProtKB=A0ACM8ENA8 A0ACM8ENA8 LOC115312772 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8040270|UniProtKB=A0ACM8DZI7 A0ACM8DZI7 LOC8040270 PTHR13140:SF729 MYOSIN UNCONVENTIONAL MYOSIN-IE microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;actin filament-based process#GO:0030029;transport#GO:0006810;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC8036249|UniProtKB=A0ACM8E5P3 A0ACM8E5P3 how PTHR11208:SF42 RNA-BINDING PROTEIN RELATED KH DOMAIN-CONTAINING RNA-BINDING PROTEIN QKI RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8050911|UniProtKB=A0ACM8DLQ9 A0ACM8DLQ9 LOC8050911 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8029985|UniProtKB=A0ACM8DJ38 A0ACM8DJ38 waw PTHR43512:SF7 TRANSLATION FACTOR GUF1-RELATED TRANSLATION FACTOR GUF1, MITOCHONDRIAL binding#GO:0005488;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of translation#GO:0045727;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8037235|UniProtKB=A0ACM8F9X7 A0ACM8F9X7 LOC8037235 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121047283|UniProtKB=A0ACM8FG29 A0ACM8FG29 LOC121047283 PTHR11616:SF334 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1 monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;establishment of localization#GO:0051234;import into cell#GO:0098657;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8026228|UniProtKB=A0ACM8ED49 A0ACM8ED49 LOC8026228 PTHR24241:SF161 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115332211|UniProtKB=A0ACM8EDA1 A0ACM8EDA1 LOC115332211 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115326685|UniProtKB=A0ACM8EIU1 A0ACM8EIU1 LOC115326685 PTHR24413:SF240 SPECKLE-TYPE POZ PROTEIN PROTEIN ROADKILL enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 regulation of proteolysis#GO:0030162;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115328519|UniProtKB=A0ACM8E8R7 A0ACM8E8R7 LOC115328519 PTHR13248:SF4 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 2 ELONGIN-B transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of biosynthetic process#GO:0009891;protein metabolic process#GO:0019538;post-transcriptional gene silencing#GO:0016441;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul5-RING ubiquitin ligase complex#GO:0031466;Cul2-RING ubiquitin ligase complex#GO:0031462;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC115327576|UniProtKB=A0ACM8F4F6 A0ACM8F4F6 LOC115327576 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8030411|UniProtKB=A0ACM8EXQ1 A0ACM8EXQ1 LOC8030411 PTHR24399:SF70 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8027193|UniProtKB=A0ACM8E6Y7 A0ACM8E6Y7 par-6 PTHR14102:SF11 PAR-6-RELATED LD29223P protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell junction organization#GO:0034330;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;centrosome cycle#GO:0007098;cell-cell junction maintenance#GO:0045217;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;establishment or maintenance of cell polarity#GO:0007163;cell-cell junction organization#GO:0045216 catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell junction protein#PC00070;tight junction#PC00214 IXOSC|EnsemblGenome=LOC121048137|UniProtKB=A0ACM8FHS6 A0ACM8FHS6 LOC121048137 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115315177|UniProtKB=A0ACM8F107 A0ACM8F107 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8032725|UniProtKB=A0ACM8DNY4 A0ACM8DNY4 Grasp65 PTHR12893:SF0 GOLGI REASSEMBLY STACKING PROTEIN GRASP GRASP65 cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120840002|UniProtKB=A0ACM8ENJ8 A0ACM8ENJ8 LOC120840002 PTHR46060:SF3 MARINER MOS1 TRANSPOSASE-LIKE PROTEIN PROTEIN GVQW3 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121837643|UniProtKB=A0ACM8G4E2 A0ACM8G4E2 LOC121837643 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837758|UniProtKB=A0ACM8EIA6 A0ACM8EIA6 LOC120837758 PTHR21563:SF3 ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN ZINC FINGER C3H1 DOMAIN-CONTAINING PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120837997|UniProtKB=A0ACM8EIT9 A0ACM8EIT9 LOC120837997 PTHR12274:SF3 GRANULIN GRANULIN PRECURSOR cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC115321386|UniProtKB=A0ACM8F4D1 A0ACM8F4D1 LOC115321386 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115324389|UniProtKB=A0ACM8FIE0 A0ACM8FIE0 LOC115324389 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046699|UniProtKB=A0ACM8FDC1 A0ACM8FDC1 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN transferase#PC00220;acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC8042986|UniProtKB=A0ACM8FE52 A0ACM8FE52 PTHR11042:SF91 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8033466|UniProtKB=A0ACM8DXS0 A0ACM8DXS0 LOC8033466 PTHR13992:SF39 NUCLEAR RECEPTOR CO-REPRESSOR RELATED NCOR SMRTER, ISOFORM G regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8025152|UniProtKB=A0ACM8DPK0 A0ACM8DPK0 pps PTHR11477:SF51 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN PROTEIN PARTNER OF SNF, ISOFORM B general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120839108|UniProtKB=A0ACM8EMD0 A0ACM8EMD0 LOC120839108 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026524|UniProtKB=A0ACM8DHV5 A0ACM8DHV5 LOC8026524 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;small molecule binding#GO:0036094;catalytic activity#GO:0003824;binding#GO:0005488;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115330597|UniProtKB=A0ACM8EBG4 A0ACM8EBG4 LOC115330597 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121835701|UniProtKB=A0ACM8FWK8 A0ACM8FWK8 LOC121835701 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8023502|UniProtKB=A0ACM8DH66 A0ACM8DH66 LOC8023502 PTHR11937:SF387 ACTIN ACTIN, INDIRECT FLIGHT MUSCLE-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Integrin signalling pathway#P00034>Actin#P00944;Huntington disease#P00029>Actin#P00807;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cadherin signaling pathway#P00012>F-actin#P00470;Wnt signaling pathway#P00057>NFAT Target Genes#G01559;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512 IXOSC|EnsemblGenome=LOC121836850|UniProtKB=A0ACM8G0H8 A0ACM8G0H8 LOC121836850 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838563|UniProtKB=A0ACM8EJI3 A0ACM8EJI3 LOC120838563 PTHR12587:SF14 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN AT31531P structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 neuromuscular junction development#GO:0007528;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043 presynapse#GO:0098793;presynaptic active zone#GO:0048786;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8034665|UniProtKB=A0ACM8EKI5 A0ACM8EKI5 LOC8034665 PTHR43416:SF5 DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL-RELATED DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 transferase#PC00220 IXOSC|EnsemblGenome=LOC115331999|UniProtKB=A0ACM8F7N6 A0ACM8F7N6 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8024008|UniProtKB=A0ACM8FFW3 A0ACM8FFW3 LOC8024008 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115324015|UniProtKB=A0ACM8EG95 A0ACM8EG95 LOC115324015 PTHR47972:SF45 KINESIN-LIKE PROTEIN KLP-3 PROTEIN CLARET SEGREGATIONAL microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC115329685|UniProtKB=A0ACM8EPN5 A0ACM8EPN5 LOC115329685 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8029080|UniProtKB=A0ACM8EEA9 A0ACM8EEA9 Fcp1 PTHR23081:SF36 RNA POLYMERASE II CTD PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Transcription regulation by bZIP transcription factor#P00055>TFIIF#P01394;General transcription regulation#P00023>TFIIF#P00665 IXOSC|EnsemblGenome=LOC115323249|UniProtKB=A0ACM8FFK0 A0ACM8FFK0 LOC115323249 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041950|UniProtKB=A0ACM8F4K7 A0ACM8F4K7 LOC8041950 PTHR23506:SF4 GH10249P PORTABELLA solute:sodium symporter activity#GO:0015370;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078 synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular vesicle#GO:0097708;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;neuron projection#GO:0043005;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;axon#GO:0030424;neuron projection terminus#GO:0044306;intracellular membrane-bounded organelle#GO:0043231;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;axon terminus#GO:0043679;organelle membrane#GO:0031090;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089 IXOSC|EnsemblGenome=LOC8053939|UniProtKB=A0ACM8DLV2 A0ACM8DLV2 LOC8053939 PTHR21660:SF1 THIOESTERASE SUPERFAMILY MEMBER-RELATED ACYL-COENZYME A THIOESTERASE 13 acyl-CoA hydrolase activity#GO:0016289;catalytic activity#GO:0003824;deacylase activity#GO:0160215;fatty acyl-CoA hydrolase activity#GO:0047617;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8042994|UniProtKB=A0ACM8DW63 A0ACM8DW63 LOC8042994 PTHR11802:SF201 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CTSA-1.1 peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine-type peptidase activity#GO:0008236 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8030715|UniProtKB=A0ACM8DUD6 A0ACM8DUD6 Ero1L PTHR12613:SF0 ERO1-RELATED ERO1-LIKE PROTEIN protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 signal transduction#GO:0007165;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;protein folding#GO:0006457;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;protein metabolic process#GO:0019538 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8034010|UniProtKB=A0ACM8E9L6 A0ACM8E9L6 LOC8034010 PTHR43982:SF6 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 2-RELATED cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;binding#GO:0005488;protein-containing complex binding#GO:0044877;hydrolase activity#GO:0016787 negative regulation of catabolic process#GO:0009895;regulation of cellular response to stress#GO:0080135;regulation of protein catabolic process#GO:0042176;negative regulation of metabolic process#GO:0009892;regulation of ERAD pathway#GO:1904292;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;negative regulation of biological process#GO:0048519;regulation of catabolic process#GO:0009894;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;negative regulation of response to stimulus#GO:0048585;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121834283|UniProtKB=A0ACM8FPR2 A0ACM8FPR2 PTHR10288:SF347 KH DOMAIN CONTAINING RNA BINDING PROTEIN MUSHROOM-BODY EXPRESSED, ISOFORM K mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115332080|UniProtKB=A0ACM8EDR4 A0ACM8EDR4 LOC115332080 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050898|UniProtKB=A0ACM8ES20 A0ACM8ES20 LOC8050898 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115317693|UniProtKB=A0ACM8FJ88 A0ACM8FJ88 LOC115317693 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121837855|UniProtKB=A0ACM8G5F2 A0ACM8G5F2 LOC121837855 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120836340|UniProtKB=A0ACM8F8K5 A0ACM8F8K5 LOC120836340 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115314789|UniProtKB=A0ACM8EXG7 A0ACM8EXG7 LOC115314789 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120837071|UniProtKB=A0ACM8EG51 A0ACM8EG51 LOC120837071 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115326688|UniProtKB=A0ACM8E680 A0ACM8E680 LOC115326688 PTHR16296:SF2 UNCHARACTERIZED HYPOTHALAMUS PROTEIN HT007 TRANSMEMBRANE PROTEIN 126A mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120849131|UniProtKB=A0ACM8G942 A0ACM8G942 LOC120849131 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 IXOSC|EnsemblGenome=LOC8050866|UniProtKB=A0ACM8DLL7 A0ACM8DLL7 LOC8050866 PTHR10827:SF52 RETICULOCALBIN RETICULOCALBIN-3 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calcium-binding protein#PC00060;calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC115326398|UniProtKB=A0ACM8E6W6 A0ACM8E6W6 l(1)G0007 PTHR18934:SF91 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16 catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8036438|UniProtKB=A0ACM8DJZ5 A0ACM8DJZ5 LOC8036438 PTHR28360:SF1 DYNACTIN SUBUNIT 3 DYNACTIN SUBUNIT 3 cytoskeleton-dependent cytokinesis#GO:0061640;cell cycle#GO:0007049;cytokinesis#GO:0000910;cell division#GO:0051301;cell cycle process#GO:0022402;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=ISCI019804|UniProtKB=Q4PM47 Q4PM47 RpS29 PTHR12010:SF2 40S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN US14 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;zinc ion binding#GO:0008270 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115314644|UniProtKB=A0ACM8DU10 A0ACM8DU10 LOC115314644 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323566|UniProtKB=A0ACM8FYK8 A0ACM8FYK8 LOC115323566 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115310707|UniProtKB=A0ACM8ESJ4 A0ACM8ESJ4 LOC115310707 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8050871|UniProtKB=A0ACM8DLN7 A0ACM8DLN7 Pop4 PTHR13348:SF0 RIBONUCLEASE P SUBUNIT P29 RIBONUCLEASE P PROTEIN SUBUNIT P29 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular protein-containing complex#GO:0140535;ribonucleoprotein complex#GO:1990904;endonuclease complex#GO:1905348;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;catalytic complex#GO:1902494;ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991 endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC115315628|UniProtKB=A0ACM8FTQ6 A0ACM8FTQ6 LOC115315628 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234;lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120846384|UniProtKB=A0ACM8F1Z0 A0ACM8F1Z0 LOC120846384 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836919|UniProtKB=A0ACM8G0C8 A0ACM8G0C8 LOC120836919 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8052428|UniProtKB=A0ACM8DLP7 A0ACM8DLP7 LOC8052428 PTHR10989:SF16 ANDROGEN-INDUCED PROTEIN 1-RELATED AT02829P-RELATED catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 long-chain fatty acid metabolic process#GO:0001676;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062 IXOSC|EnsemblGenome=LOC8050433|UniProtKB=A0ACM8FB30 A0ACM8FB30 Lrch PTHR48051:SF21 FAMILY NOT NAMED CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8053600|UniProtKB=A0ACM8DNK6 A0ACM8DNK6 LOC8053600 PTHR19432:SF35 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8032945|UniProtKB=A0ACM8DVJ4 A0ACM8DVJ4 LOC8032945 PTHR12269:SF1 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER transporter#PC00227 IXOSC|EnsemblGenome=LOC8023370|UniProtKB=A0ACM8EIF0 A0ACM8EIF0 LOC8023370 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120845321|UniProtKB=A0ACM8G5I2 A0ACM8G5I2 LOC120845321 PTHR11465:SF9 CATALASE CATALASE oxidoreductase activity#GO:0016491;heme binding#GO:0020037;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;binding#GO:0005488 response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;response to oxygen-containing compound#GO:1901700;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to chemical#GO:0042221;hydrogen peroxide metabolic process#GO:0042743;response to stress#GO:0006950;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 peroxidase#PC00180 IXOSC|EnsemblGenome=LOC121834081|UniProtKB=A0ACM8FP50 A0ACM8FP50 PTHR16515:SF77 PR DOMAIN ZINC FINGER PROTEIN SUBFAMILY NOT NAMED regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120844575|UniProtKB=A0ACM8G8H3 A0ACM8G8H3 LOC120844575 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839727|UniProtKB=A0ACM8ELZ1 A0ACM8ELZ1 LOC120839727 PTHR46376:SF1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of Ras protein signal transduction#GO:0046578;negative regulation of intracellular signal transduction#GO:1902532 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;ubiquitin ligase complex#GO:0000151;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;Cul3-RING ubiquitin ligase complex#GO:0031463;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC120851155|UniProtKB=A0ACM8FBE7 A0ACM8FBE7 LOC120851155 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120843343|UniProtKB=A0ACM8EVR1 A0ACM8EVR1 LOC120843343 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8034137|UniProtKB=A0ACM8E4A1 A0ACM8E4A1 LOC8034137 PTHR14972:SF8 AGAP011572-PA GLUCOCORTICOID-INDUCED TRANSCRIPT 1 PROTEIN-LIKE ISOFORM X1 IXOSC|EnsemblGenome=LOC8051557|UniProtKB=A0ACM8EKW9 A0ACM8EKW9 LOC8051557 PTHR23138:SF94 RAN BINDING PROTEIN RAN-SPECIFIC GTPASE-ACTIVATING PROTEIN nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;intracellular transport#GO:0046907;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8032333|UniProtKB=A0ACM8G4R3 A0ACM8G4R3 LOC8032333 PTHR47303:SF1 FAMILY NOT NAMED NF-KAPPA-B INHIBITOR BETA cellular response to biotic stimulus#GO:0071216;cellular response to stimulus#GO:0051716;response to molecule of bacterial origin#GO:0002237;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;cellular response to chemical stimulus#GO:0070887;response to bacterium#GO:0009617;response to oxygen-containing compound#GO:1901700;cellular response to lipopolysaccharide#GO:0071222;response to biotic stimulus#GO:0009607;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;response to lipid#GO:0033993;cellular response to lipid#GO:0071396;response to chemical#GO:0042221;response to other organism#GO:0051707;cellular response to molecule of bacterial origin#GO:0071219;response to lipopolysaccharide#GO:0032496;response to external stimulus#GO:0009605 IXOSC|EnsemblGenome=LOC115323017|UniProtKB=A0ACM8EHP3 A0ACM8EHP3 LOC115323017 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=LOC115332050|UniProtKB=A0ACM8G2M0 A0ACM8G2M0 LOC115332050 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC115319878|UniProtKB=A0ACM8EF88 A0ACM8EF88 LOC115319878 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8039834|UniProtKB=A0ACM8DKE1 A0ACM8DKE1 Polr2D PTHR21297:SF0 DNA-DIRECTED RNA POLYMERASE II DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB4 protein binding#GO:0005515;translation initiation factor binding#GO:0031369;binding#GO:0005488 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 IXOSC|EnsemblGenome=LOC115328077|UniProtKB=A0ACM8ERC2 A0ACM8ERC2 LOC115328077 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8041526|UniProtKB=A0ACM8E071 A0ACM8E071 Vha100-1 PTHR11629:SF114 VACUOLAR PROTON ATPASES V-TYPE PROTON ATPASE SUBUNIT A transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;protein binding#GO:0005515 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;proton transmembrane transport#GO:1902600;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886;proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC115326360|UniProtKB=A0ACM8E5W6 A0ACM8E5W6 LOC115326360 PTHR15066:SF0 TRANSMEMBRANE PROTEIN 187 TRANSMEMBRANE PROTEIN 187 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121838025|UniProtKB=A0ACM8G792 A0ACM8G792 LOC121838025 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028352|UniProtKB=A0ACM8DJQ3 A0ACM8DJQ3 LOC8028352 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115318902|UniProtKB=A0ACM8DYG7 A0ACM8DYG7 LOC115318902 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8043063|UniProtKB=A0ACM8E8C9 A0ACM8E8C9 Tango10 PTHR24410:SF41 HL07962P-RELATED HL07962P defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8040541|UniProtKB=A0ACM8G1Y4 A0ACM8G1Y4 BicC PTHR10627:SF83 SCP160 PROTEIN BICAUDAL C intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120840970|UniProtKB=A0ACM8EQR6 A0ACM8EQR6 LOC120840970 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8050649|UniProtKB=A0ACM8EY85 A0ACM8EY85 LOC8050649 PTHR28593:SF3 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC115315765|UniProtKB=A0ACM8ES36 A0ACM8ES36 LOC115315765 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115308497|UniProtKB=A0ACM8DMJ2 A0ACM8DMJ2 LOC115308497 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850683|UniProtKB=A0ACM8FBH0 A0ACM8FBH0 LOC120850683 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331747|UniProtKB=A0ACM8EDG6 A0ACM8EDG6 LOC115331747 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8036915|UniProtKB=A0ACM8DS94 A0ACM8DS94 LOC8036915 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120836237|UniProtKB=A0ACM8ERF4 A0ACM8ERF4 LOC120836237 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8042581|UniProtKB=A0ACM8G1F8 A0ACM8G1F8 LOC8042581 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8030822|UniProtKB=A0ACM8FEV1 A0ACM8FEV1 LOC8030822 PTHR22974:SF21 MIXED LINEAGE PROTEIN KINASE DUAL SPECIFICITY PROTEIN KINASE TTK phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;negative regulation of biological process#GO:0048519;meiotic cell cycle process#GO:1903046;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;regulation of meiotic cell cycle#GO:0051445;negative regulation of mitotic nuclear division#GO:0045839;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell cycle#GO:0045786;negative regulation of chromosome segregation#GO:0051985;meiotic cell cycle#GO:0051321;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;chromosome segregation#GO:0007059;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;negative regulation of chromosome organization#GO:2001251;sexual reproduction#GO:0019953;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of reproductive process#GO:2000241;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8038103|UniProtKB=A0ACM8DN35 A0ACM8DN35 TM9SF2 PTHR10766:SF176 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120837007|UniProtKB=A0ACM8EGB3 A0ACM8EGB3 LOC120837007 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837360|UniProtKB=A0ACM8G4B5 A0ACM8G4B5 LOC121837360 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121838284|UniProtKB=A0ACM8G763 A0ACM8G763 LOC121838284 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8032794|UniProtKB=A0ACM8DUM8 A0ACM8DUM8 LOC8032794 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8023738|UniProtKB=A0ACM8E248 A0ACM8E248 LOC8023738 PTHR13563:SF5 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG C RNA binding#GO:0003723;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;mitochondrion#GO:0005739 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC115325717|UniProtKB=A0ACM8F505 A0ACM8F505 LOC115325717 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8036652|UniProtKB=A0ACM8DR76 A0ACM8DR76 Pi3K92E PTHR10048:SF118 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 biological regulation#GO:0065007;biosynthetic process#GO:0009058;intracellular signaling cassette#GO:0141124;glycerophospholipid metabolic process#GO:0006650;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854 extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 kinase#PC00137 Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;p53 pathway feedback loops 2#P04398>PI3K#P04661;PDGF signaling pathway#P00047>PI3K#P01168;Apoptosis signaling pathway#P00006>PI3K#P00310;Ras Pathway#P04393>PI3K#P04567;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;PI3 kinase pathway#P00048>P110ACT#P01177;VEGF signaling pathway#P00056>PI3K#P01413;PI3 kinase pathway#P00048>p110#P01192;FGF signaling pathway#P00021>PI3K#P00640;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;EGF receptor signaling pathway#P00018>PI3K#P00557;Angiogenesis#P00005>PI3K#P00236 IXOSC|EnsemblGenome=LOC120840000|UniProtKB=A0ACM8G957 A0ACM8G957 LOC120840000 PTHR24201:SF18 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 IXOSC|EnsemblGenome=LOC8028519|UniProtKB=A0ACM8EKS7 A0ACM8EKS7 LOC8028519 PTHR22600:SF59 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE A hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;glycosaminoglycan metabolic process#GO:0030203;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;lysosome#GO:0005764;cell periphery#GO:0071944 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115332484|UniProtKB=A0ACM8ERE4 A0ACM8ERE4 LOC115332484 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8039669|UniProtKB=A0ACM8EEZ6 A0ACM8EEZ6 Ipk1 PTHR14456:SF2 INOSITOL POLYPHOSPHATE KINASE 1 INOSITOL-PENTAKISPHOSPHATE 2-KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 kinase#PC00137 IXOSC|EnsemblGenome=LOC120846838|UniProtKB=A0ACM8F3D2 A0ACM8F3D2 LOC120846838 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026531|UniProtKB=A0ACM8DWP2 A0ACM8DWP2 LOC8026531 PTHR13399:SF4 TRANSLOCON-ASSOCIATED PROTEIN TRAP , GAMMA SUBUNIT TBC1 DOMAIN FAMILY MEMBER 30 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC8051369|UniProtKB=A0ACM8DLX0 A0ACM8DLX0 LOC8051369 PTHR13411:SF6 PLASMINOGEN RECEPTOR (KT) PLASMINOGEN RECEPTOR (KT) IXOSC|EnsemblGenome=LOC8051775|UniProtKB=A0ACM8DLF9 A0ACM8DLF9 mRF1 PTHR43804:SF7 LD18447P LD18447P translation release factor#PC00225;translational protein#PC00263;translation factor#PC00223 IXOSC|EnsemblGenome=LOC8037298|UniProtKB=A0ACM8DZR9 A0ACM8DZR9 crn PTHR11246:SF3 PRE-MRNA SPLICING FACTOR CROOKED NECK-LIKE PROTEIN 1 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613 spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115323718|UniProtKB=A0ACM8FTW7 A0ACM8FTW7 LOC115323718 PTHR14296:SF20 REMODELING AND SPACING FACTOR 1 DIKAR, ISOFORM F binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;cellular component biogenesis#GO:0044085;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949 IXOSC|EnsemblGenome=LOC8036755|UniProtKB=A0ACM8DTC1 A0ACM8DTC1 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120849195|UniProtKB=A0ACM8F7C1 A0ACM8F7C1 LOC120849195 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8041160|UniProtKB=A0ACM8E1M9 A0ACM8E1M9 Cdc5 PTHR45885:SF6 CELL DIVISION CYCLE 5-LIKE PROTEIN CELL DIVISION CYCLE 5-LIKE PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;mRNA splicing, via spliceosome#GO:0000398;regulation of transcription by RNA polymerase II#GO:0006357;mRNA metabolic process#GO:0016071 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC115332176|UniProtKB=A0ACM8ED64 A0ACM8ED64 LOC115332176 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8053391|UniProtKB=A0ACM8DU60 A0ACM8DU60 LOC8053391 PTHR11361:SF148 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN MSH6 nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;double-stranded DNA binding#GO:0003690;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;mismatch repair#GO:0006298;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8040867|UniProtKB=A0ACM8F9Y2 A0ACM8F9Y2 LOC8040867 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120840843|UniProtKB=A0ACM8FEZ7 A0ACM8FEZ7 LOC120840843 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029614|UniProtKB=A0ACM8DVE2 A0ACM8DVE2 Swip-1 PTHR13025:SF6 EF-HAND DOMAIN-CONTAINING PROTEIN D EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC115316795|UniProtKB=A0ACM8DWV9 A0ACM8DWV9 LOC115316795 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 IXOSC|EnsemblGenome=LOC8026462|UniProtKB=A0ACM8DV89 A0ACM8DV89 LOC8026462 PTHR23138:SF141 RAN BINDING PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP50 protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120840851|UniProtKB=A0ACM8FLP3 A0ACM8FLP3 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031549|UniProtKB=A0ACM8E7I1 A0ACM8E7I1 GABA-B-R1 PTHR10519:SF77 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 IXOSC|EnsemblGenome=LOC115309616|UniProtKB=A0ACM8DP19 A0ACM8DP19 LOC115309616 PTHR24006:SF702 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC115324566|UniProtKB=A0ACM8ETG6 A0ACM8ETG6 LOC115324566 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8043153|UniProtKB=A0ACM8EC87 A0ACM8EC87 PTHR13710:SF108 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q4 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA recombination#GO:0006310;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC115331401|UniProtKB=A0ACM8EX71 A0ACM8EX71 LOC115331401 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8053346|UniProtKB=A0ACM8EBH7 A0ACM8EBH7 LOC8053346 PTHR37458:SF1 THISBE THISBE cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8023571|UniProtKB=A0ACM8E613 A0ACM8E613 LOC8023571 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8039016|UniProtKB=A0ACM8DPU5 A0ACM8DPU5 LOC8039016 PTHR11616:SF328 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8029266|UniProtKB=A0ACM8DTS5 A0ACM8DTS5 Frmd5 PTHR23280:SF32 4.1 G PROTEIN FI22325P1 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8051813|UniProtKB=A0ACM8FC35 A0ACM8FC35 LOC8051813 PTHR12103:SF15 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5' NUCLEOTIDASE B, ISOFORM G phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253 nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8029481|UniProtKB=A0ACM8G340 A0ACM8G340 LOC8029481 PTHR23055:SF198 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 1 enzyme activator activity#GO:0008047;cyclase regulator activity#GO:0010851;molecular function regulator activity#GO:0098772;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cation binding#GO:0043169 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC115309498|UniProtKB=A0ACM8F3J4 A0ACM8F3J4 LOC115309498 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115328413|UniProtKB=A0ACM8E827 A0ACM8E827 LOC115328413 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120846403|UniProtKB=A0ACM8F2A3 A0ACM8F2A3 LOC120846403 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327994|UniProtKB=A0ACM8FTF4 A0ACM8FTF4 LOC115327994 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321065|UniProtKB=A0ACM8ELG2 A0ACM8ELG2 LOC115321065 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8037613|UniProtKB=A0ACM8DI73 A0ACM8DI73 Adk2 PTHR45769:SF3 ADENOSINE KINASE ADENOSINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;nucleoside kinase activity#GO:0019206;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine nucleobase metabolic process#GO:0006144 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120841965|UniProtKB=A0ACM8ESV4 A0ACM8ESV4 LOC120841965 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115326957|UniProtKB=A0ACM8FZD4 A0ACM8FZD4 LOC115326957 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 chromosome#GO:0005694;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115321885|UniProtKB=A0ACM8E2M1 A0ACM8E2M1 LOC115321885 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311122|UniProtKB=A0ACM8F606 A0ACM8F606 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular process#GO:0009987;circulatory system development#GO:0072359;heart development#GO:0007507;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8037674|UniProtKB=A0ACM8DM61 A0ACM8DM61 LOC8037674 PTHR15129:SF0 SRC-ASSOCIATED ADAPTOR PROTEIN SH3 DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115324180|UniProtKB=A0ACM8G0C7 A0ACM8G0C7 LOC115324180 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120837462|UniProtKB=A0ACM8EIF9 A0ACM8EIF9 LOC120837462 PTHR12125:SF5 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8041216|UniProtKB=A0ACM8E2K9 A0ACM8E2K9 LOC8041216 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC120846174|UniProtKB=A0ACM8G5J5 A0ACM8G5J5 LOC120846174 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;binding#GO:0005488 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120849410|UniProtKB=A0ACM8F7P1 A0ACM8F7P1 LOC120849410 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8042595|UniProtKB=A0ACM8DYS3 A0ACM8DYS3 Pak3 PTHR45832:SF26 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE IXOSC|EnsemblGenome=LOC8030016|UniProtKB=A0ACM8DJ70 A0ACM8DJ70 LOC8030016 PTHR45948:SF2 DUAL SPECIFICITY PROTEIN PHOSPHATASE DDB_G0269404-RELATED DUAL SPECIFICITY PROTEIN PHOSPHATASE 15 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 IXOSC|EnsemblGenome=LOC115330989|UniProtKB=A0ACM8FAD6 A0ACM8FAD6 LOC115330989 PTHR13723:SF321 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE LONELY HEART, ISOFORM A metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 extracellular structure organization#GO:0043062;proteolysis#GO:0006508;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120840611|UniProtKB=A0ACM8FEH4 A0ACM8FEH4 LOC120840611 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8023141|UniProtKB=A0ACM8E853 A0ACM8E853 LOC8023141 PTHR23302:SF43 TRANSMEMBRANE CHANNEL-RELATED TMC DOMAIN-CONTAINING PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 IXOSC|EnsemblGenome=LOC8040492|UniProtKB=A0ACM8DQS7 A0ACM8DQS7 LOC8040492 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8044012|UniProtKB=A0ACM8FQU0 A0ACM8FQU0 LOC8044012 PTHR21532:SF0 PHOSPHODIESTERASE HL CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 36 intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;ciliary base#GO:0097546;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC8041367|UniProtKB=A0ACM8DKN8 A0ACM8DKN8 LOC8041367 PTHR21236:SF2 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;membrane fusion#GO:0061025;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi apparatus subcompartment#GO:0098791;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 structural protein#PC00211 IXOSC|EnsemblGenome=LOC8037548|UniProtKB=A0ACM8DU01 A0ACM8DU01 LOC8037548 PTHR10807:SF110 MYOTUBULARIN-RELATED FI17948P1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115329874|UniProtKB=A0ACM8G4E7 A0ACM8G4E7 LOC115329874 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC120844724|UniProtKB=A0ACM8EZC6 A0ACM8EZC6 LOC120844724 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120846837|UniProtKB=A0ACM8F3A6 A0ACM8F3A6 LOC120846837 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029036|UniProtKB=A0ACM8G3I7 A0ACM8G3I7 LOC8029036 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8032692|UniProtKB=A0ACM8FD57 A0ACM8FD57 LOC8032692 PTHR28544:SF1 PROTEIN FAM45A-RELATED DENN DOMAIN-CONTAINING PROTEIN 10-RELATED nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899 regulation of localization#GO:0032879;regulation of transport#GO:0051049;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;establishment of protein localization#GO:0045184;regulation of biological process#GO:0050789;macromolecule localization#GO:0033036 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;late endosome#GO:0005770;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8043741|UniProtKB=A0ACM8EYU1 A0ACM8EYU1 Nup133 PTHR13405:SF11 NUCLEAR PORE COMPLEX PROTEIN NUP133 NUCLEAR PORE COMPLEX PROTEIN NUP133 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;establishment of protein localization to organelle#GO:0072594;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;gene expression#GO:0010467;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8023928|UniProtKB=A0ACM8E0E1 A0ACM8E0E1 Hus1-like PTHR12900:SF0 MITOTIC AND DNA DAMAGE CHECKPOINT PROTEIN HUS1 CHECKPOINT PROTEIN cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic DNA replication checkpoint signaling#GO:0033314;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;signaling#GO:0023052;DNA recombination#GO:0006310;metabolic process#GO:0008152;double-strand break repair#GO:0006302;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;mitotic DNA damage checkpoint signaling#GO:0044773;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;telomere maintenance#GO:0000723;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;negative regulation of cell cycle G2/M phase transition#GO:1902750;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;negative regulation of mitotic cell cycle phase transition#GO:1901991;sexual reproduction#GO:0019953;telomere organization#GO:0032200;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007 protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;site of double-strand break#GO:0035861;nucleus#GO:0005634;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121836274|UniProtKB=A0ACM8FY50 A0ACM8FY50 LOC121836274 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8028545|UniProtKB=A0ACM8DXR8 A0ACM8DXR8 LOC8028545 PTHR45709:SF6 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED LARGE SUBUNIT GTPASE 1 HOMOLOG hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8038332|UniProtKB=A0ACM8DV68 A0ACM8DV68 LOC8038332 PTHR18849:SF20 LEUCINE RICH REPEAT PROTEIN TUBULIN-SPECIFIC CHAPERONE E IXOSC|EnsemblGenome=LOC8037425|UniProtKB=A0ACM8FV34 A0ACM8FV34 LOC8037425 PTHR13382:SF89 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B SCF E3 UBIQUITIN LIGASE COMPLEX F-BOX PROTEIN POF2 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC8050770|UniProtKB=A0ACM8DLW4 A0ACM8DLW4 LOC8050770 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120849885|UniProtKB=A0ACM8F8Y8 A0ACM8F8Y8 LOC120849885 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121837206|UniProtKB=A0ACM8G2S3 A0ACM8G2S3 LOC121837206 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121838287|UniProtKB=A0ACM8G7J1 A0ACM8G7J1 LOC121838287 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8031067|UniProtKB=A0ACM8EE69 A0ACM8EE69 S2P PTHR13325:SF3 PROTEASE M50 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE 2 PROTEASE MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-2 PROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;membrane protein proteolysis#GO:0033619;regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;cellular process#GO:0009987;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;metabolic process#GO:0008152;proteolysis#GO:0006508;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;regulation of cellular response to stress#GO:0080135 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115318705|UniProtKB=A0ACM8DYC7 A0ACM8DYC7 sta PTHR11489:SF9 40S RIBOSOMAL PROTEIN SA SMALL RIBOSOMAL SUBUNIT PROTEIN US2 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;translation#GO:0006412;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115330059|UniProtKB=A0ACM8EB77 A0ACM8EB77 Gpa2 PTHR31129:SF2 GLYCOPROTEIN HORMONE ALPHA-2 GLYCOPROTEIN HORMONES ALPHA CHAIN protein binding#GO:0005515;hormone receptor binding#GO:0051427;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 IXOSC|EnsemblGenome=LOC115325485|UniProtKB=A0ACM8E5W4 A0ACM8E5W4 LOC115325485 PTHR12763:SF28 FAMILY NOT NAMED GEO10507P1-RELATED IXOSC|EnsemblGenome=LOC8025588|UniProtKB=A0ACM8DT94 A0ACM8DT94 LOC8025588 PTHR15690:SF0 NUCLEAR RECEPTOR COACTIVATOR 6 NUCLEAR RECEPTOR COACTIVATOR 6 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115328983|UniProtKB=A0ACM8E8U6 A0ACM8E8U6 MED22 PTHR12434:SF6 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 22 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120837645|UniProtKB=A0ACM8EHF0 A0ACM8EHF0 LOC120837645 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029783|UniProtKB=A0ACM8FGY2 A0ACM8FGY2 Acsl PTHR43272:SF118 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lipid droplet#GO:0005811;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944 ligase#PC00142 IXOSC|EnsemblGenome=LOC8052153|UniProtKB=A0ACM8DNG6 A0ACM8DNG6 hoip PTHR23105:SF38 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER NHP2-LIKE PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115309970|UniProtKB=A0ACM8DP53 A0ACM8DP53 LOC115309970 PTHR14273:SF0 LYR MOTIF-CONTAINING PROTEIN 1 LYR MOTIF-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC115308842|UniProtKB=A0ACM8EVP4 A0ACM8EVP4 LOC115308842 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839904|UniProtKB=A0ACM8G1Q7 A0ACM8G1Q7 LOC120839904 PTHR46780:SF21 PROTEIN EVA-1 D-GALACTOSIDE-SPECIFIC LECTIN ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8037393|UniProtKB=A0ACM8DWH0 A0ACM8DWH0 Cwc25 PTHR16196:SF0 CELL CYCLE CONTROL PROTEIN CWF25 PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120838459|UniProtKB=A0ACM8EK27 A0ACM8EK27 LOC120838459 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;small molecule binding#GO:0036094;catalytic activity#GO:0003824;binding#GO:0005488;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120850755|UniProtKB=A0ACM8FNF9 A0ACM8FNF9 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8041502|UniProtKB=A0ACM8EHH3 A0ACM8EHH3 LOC8041502 PTHR42643:SF45 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115316928|UniProtKB=A0ACM8DWX8 A0ACM8DWX8 LOC115316928 PTHR24365:SF530 TOLL-LIKE RECEPTOR TOLL-9, ISOFORM A molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8041498|UniProtKB=A0ACM8G0A7 A0ACM8G0A7 mRpL19 PTHR15680:SF21 RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN BL19M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8041507|UniProtKB=A0ACM8DKQ6 A0ACM8DKQ6 LOC8041507 PTHR47968:SF75 CENTROMERE PROTEIN E KINESIN-LIKE PROTEIN TEA2 IXOSC|EnsemblGenome=LOC121838443|UniProtKB=A0ACM8G818 A0ACM8G818 LOC121838443 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120841188|UniProtKB=A0ACM8ER07 A0ACM8ER07 LOC120841188 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330243|UniProtKB=A0ACM8EVE3 A0ACM8EVE3 LOC115330243 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322096|UniProtKB=A0ACM8FBQ3 A0ACM8FBQ3 Ube4A PTHR13931:SF16 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 A catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to endoplasmic reticulum stress#GO:0034976;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120848217|UniProtKB=A0ACM8F5A0 A0ACM8F5A0 LOC120848217 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=ISCI003184|UniProtKB=B7PDC5 B7PDC5 gatA PTHR11895:SF179 TRANSAMIDASE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040654|UniProtKB=A0ACM8FKZ2 A0ACM8FKZ2 LOC8040654 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC120846241|UniProtKB=A0ACM8F1L2 A0ACM8F1L2 LOC120846241 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8043182|UniProtKB=A0ACM8EBD7 A0ACM8EBD7 LOC8043182 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8029424|UniProtKB=A0ACM8DI46 A0ACM8DI46 LOC8029424 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8029401|UniProtKB=A0ACM8DUP6 A0ACM8DUP6 rtet PTHR23504:SF126 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 BCDNA.LD28419 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8040427|UniProtKB=A0ACM8FII0 A0ACM8FII0 LOC8040427 PTHR46830:SF2 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220 IXOSC|EnsemblGenome=LOC120839840|UniProtKB=A0ACM8EN72 A0ACM8EN72 LOC120839840 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121832990|UniProtKB=A0ACM8FWF6 A0ACM8FWF6 LOC121832990 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115326502|UniProtKB=A0ACM8E621 A0ACM8E621 LOC115326502 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053091|UniProtKB=A0ACM8E8U8 A0ACM8E8U8 LOC8053091 PTHR23216:SF2 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8035841|UniProtKB=A0ACM8EH91 A0ACM8EH91 LOC8035841 PTHR18945:SF920 NEUROTRANSMITTER GATED ION CHANNEL IP12579P membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC115309879|UniProtKB=A0ACM8DP16 A0ACM8DP16 LOC115309879 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC120849000|UniProtKB=A0ACM8F6V2 A0ACM8F6V2 LOC120849000 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324322|UniProtKB=A0ACM8E3T1 A0ACM8E3T1 LOC115324322 PTHR11544:SF148 COLD SHOCK DOMAIN CONTAINING PROTEINS LD37574P binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8043290|UniProtKB=A0ACM8EJG6 A0ACM8EJG6 LOC8043290 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115314027|UniProtKB=A0ACM8ER13 A0ACM8ER13 LOC115314027 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8041280|UniProtKB=A0ACM8EHV9 A0ACM8EHV9 PPP4R2r PTHR16487:SF0 PPP4R2-RELATED PROTEIN SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 2 enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC8039543|UniProtKB=A0ACM8FC14 A0ACM8FC14 LOC8039543 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115331289|UniProtKB=A0ACM8F0P3 A0ACM8F0P3 LOC115331289 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8028697|UniProtKB=A0ACM8FQ38 A0ACM8FQ38 LOC8028697 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121837028|UniProtKB=A0ACM8G1F3 A0ACM8G1F3 LOC121837028 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043729|UniProtKB=A0ACM8E2G0 A0ACM8E2G0 LOC8043729 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8030293|UniProtKB=A0ACM8DYH0 A0ACM8DYH0 U2af38 PTHR12620:SF8 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT U2 SMALL NUCLEAR RNA AUXILIARY FACTOR 1 pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120842022|UniProtKB=A0ACM8FGA6 A0ACM8FGA6 LOC120842022 PTHR43903:SF30 NEUROLIGIN NEUROLIGIN 3, ISOFORM B signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;nervous system development#GO:0007399;cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;signaling#GO:0023052;synapse assembly#GO:0007416;endocytosis#GO:0006897;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;cellular localization#GO:0051641;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;postsynapse organization#GO:0099173;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856 synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;postsynapse#GO:0098794;plasma membrane#GO:0005886;cell surface#GO:0009986;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8027884|UniProtKB=A0ACM8DQD8 A0ACM8DQD8 LOC8027884 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=LOC8053536|UniProtKB=A0ACM8EY17 A0ACM8EY17 senju PTHR10231:SF50 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-GALACTOSE TRANSPORTER SENJU carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;UDP-galactose transmembrane transporter activity#GO:0005459;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transporter#PC00227 IXOSC|EnsemblGenome=LOC121833829|UniProtKB=A0ACM8FNA2 A0ACM8FNA2 PTHR47633:SF16 IMMUNOGLOBULIN CAVP-TARGET PROTEIN-LIKE IXOSC|EnsemblGenome=LOC120846193|UniProtKB=A0ACM8F1Q3 A0ACM8F1Q3 LOC120846193 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841018|UniProtKB=A0ACM8FQ72 A0ACM8FQ72 LOC120841018 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8038800|UniProtKB=A0ACM8EHW9 A0ACM8EHW9 twin PTHR12121:SF100 CARBON CATABOLITE REPRESSOR PROTEIN 4 POLY(A)-SPECIFIC RIBONUCLEASE catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of mRNA metabolic process#GO:1903311;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;CCR4-NOT complex#GO:0030014 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC8031963|UniProtKB=A0ACM8E413 A0ACM8E413 LOC8031963 PTHR46617:SF3 FORKHEAD BOX PROTEIN G1 FORKHEAD BOX PROTEIN G1 DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8037038|UniProtKB=A0ACM8EDH2 A0ACM8EDH2 eIF2gamma PTHR42854:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051;RNA binding#GO:0003723;tRNA binding#GO:0000049;translation initiation factor activity#GO:0003743 biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8030846|UniProtKB=A0ACM8EB75 A0ACM8EB75 LOC8030846 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831 cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC115332843|UniProtKB=A0ACM8EE72 A0ACM8EE72 LOC115332843 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120845427|UniProtKB=A0ACM8F0P8 A0ACM8F0P8 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051213|UniProtKB=A0ACM8FN91 A0ACM8FN91 LOC8051213 PTHR23031:SF15 RHOPHILIN LD12055P biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament organization#GO:0110053;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;regulation of actin filament bundle assembly#GO:0032231;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of cytoskeleton organization#GO:0051494 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053482|UniProtKB=A0ACM8DLN9 A0ACM8DLN9 LOC8053482 PTHR10894:SF0 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 56 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515 protein-containing complex#GO:0032991;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8040736|UniProtKB=A0ACM8DZV4 A0ACM8DZV4 LOC8040736 PTHR11995:SF14 NADH DEHYDROGENASE NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 7, MITOCHONDRIAL NADH dehydrogenase activity#GO:0003954;monoatomic cation transmembrane transporter activity#GO:0008324;oxidoreductase activity, acting on NAD(P)H#GO:0016651;electron transfer activity#GO:0009055;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;generation of precursor metabolites and energy#GO:0006091;transport#GO:0006810;metabolic process#GO:0008152;aerobic respiration#GO:0009060;monoatomic ion transport#GO:0006811;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;energy derivation by oxidation of organic compounds#GO:0015980;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular respiration#GO:0045333 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121046098|UniProtKB=A0ACM8FBV4 A0ACM8FBV4 LOC121046098 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8030777|UniProtKB=A0ACM8G5Y4 A0ACM8G5Y4 LOC8030777 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120848271|UniProtKB=A0ACM8F5Q9 A0ACM8F5Q9 Strump PTHR15691:SF6 WASH COMPLEX SUBUNIT 5 WASH COMPLEX SUBUNIT 5 supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;actin filament-based process#GO:0030029;regulation of cytoskeleton organization#GO:0051493;actin filament polymerization#GO:0030041;regulation of cellular component organization#GO:0051128;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;protein polymerization#GO:0051258;regulation of supramolecular fiber organization#GO:1902903;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;actin filament organization#GO:0007015;endosome organization#GO:0007032;vesicle organization#GO:0016050;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970;cytoskeleton organization#GO:0007010;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115333209|UniProtKB=A0ACM8EFP8 A0ACM8EFP8 LOC115333209 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120845980|UniProtKB=A0ACM8F142 A0ACM8F142 LOC120845980 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC121836835|UniProtKB=A0ACM8G0V0 A0ACM8G0V0 LOC121836835 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846472|UniProtKB=A0ACM8F2E3 A0ACM8F2E3 PTHR45999:SF4 UNC-13-4A, ISOFORM B UNC-13-4A, ISOFORM B IXOSC|EnsemblGenome=LOC8043463|UniProtKB=A0ACM8FX66 A0ACM8FX66 LOC8043463 PTHR11640:SF170 NEPHRIN IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8028730|UniProtKB=A0ACM8EDV3 A0ACM8EDV3 LOC8028730 PTHR12522:SF4 ZINC-FINGER PROTEIN NOLZ1-RELATED ZINC FINGER PROTEIN ELBOW negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8041734|UniProtKB=A0ACM8E4L9 A0ACM8E4L9 LOC8041734 PTHR12818:SF0 TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE TRNA (ADENINE(37)-N6)-METHYLTRANSFERASE catalytic activity, acting on a tRNA#GO:0140101;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 IXOSC|EnsemblGenome=LOC115316513|UniProtKB=A0ACM8DWN1 A0ACM8DWN1 LOC115316513 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033473|UniProtKB=A0ACM8G1K7 A0ACM8G1K7 LOC8033473 PTHR21037:SF2 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 53 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8027344|UniProtKB=A0ACM8DIZ2 A0ACM8DIZ2 LOC8027344 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115312530|UniProtKB=A0ACM8DRU4 A0ACM8DRU4 LOC115312530 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330799|UniProtKB=A0ACM8EBD6 A0ACM8EBD6 LOC115330799 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120840200|UniProtKB=A0ACM8ENW0 A0ACM8ENW0 LOC120840200 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120837454|UniProtKB=A0ACM8EIF8 A0ACM8EIF8 PTHR31649:SF1 AGAP009604-PA FARNESOIC ACID O-METHYL TRANSFERASE DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120836976|UniProtKB=A0ACM8EFW7 A0ACM8EFW7 Snap29 PTHR19305:SF42 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN 29 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;binding#GO:0005488;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;protein binding#GO:0005515 exocytosis#GO:0006887;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;export from cell#GO:0140352;vesicle fusion#GO:0006906;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane#GO:0005886 SNARE protein#PC00034;membrane traffic protein#PC00150 5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049 IXOSC|EnsemblGenome=LOC115319360|UniProtKB=A0ACM8DZ54 A0ACM8DZ54 LOC115319360 PTHR35706:SF1 F14O23.11 PROTEIN EMBRYOGENESIS-LIKE PROTEIN positive regulation of biosynthetic process#GO:0009891;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;transcription by RNA polymerase II#GO:0006366;biosynthetic process#GO:0009058;biological regulation#GO:0065007;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;chromatin remodeling#GO:0006338;DNA-templated transcription initiation#GO:0006352;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367 IXOSC|EnsemblGenome=LOC115320261|UniProtKB=A0ACM8E0N3 A0ACM8E0N3 LOC115320261 PTHR10322:SF23 DNA POLYMERASE CATALYTIC SUBUNIT DNA POLYMERASE DELTA CATALYTIC SUBUNIT catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;3'-5' exonuclease activity#GO:0008408;transferase activity#GO:0016740;DNA exonuclease activity#GO:0004529;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;hydrolase activity#GO:0016787;DNA-directed DNA polymerase activity#GO:0003887 response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-DNA complex#GO:0032993;organelle#GO:0043226;replication fork#GO:0005657;replisome#GO:0030894;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 IXOSC|EnsemblGenome=LOC120836156|UniProtKB=A0ACM8ELB2 A0ACM8ELB2 LOC120836156 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;chromosome#GO:0005694;chromatin#GO:0000785;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8029841|UniProtKB=A0ACM8DIX0 A0ACM8DIX0 Svip PTHR35269:SF1 SMALL VCP/P97-INTERACTING PROTEIN SMALL VCP_P97-INTERACTING PROTEIN positive regulation of biological process#GO:0048518;positive regulation of autophagy#GO:0010508;regulation of protein metabolic process#GO:0051246;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;negative regulation of metabolic process#GO:0009892;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of protein transport#GO:0051223;regulation of protein localization#GO:0032880;regulation of cellular response to stress#GO:0080135;positive regulation of metabolic process#GO:0009893;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of protein transport#GO:0051224;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of response to endoplasmic reticulum stress#GO:1905897;negative regulation of cellular component organization#GO:0051129;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of ERAD pathway#GO:1904292;negative regulation of protein metabolic process#GO:0051248;negative regulation of transport#GO:0051051;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein-containing complex assembly#GO:0031333;regulation of establishment of protein localization#GO:0070201;negative regulation of catabolic process#GO:0009895;regulation of protein catabolic process#GO:0042176 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC8032447|UniProtKB=A0ACM8FSS6 A0ACM8FSS6 LOC8032447 PTHR10537:SF3 DNA PRIMASE LARGE SUBUNIT DNA PRIMASE LARGE SUBUNIT nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replisome#GO:0030894;nuclear DNA-directed RNA polymerase complex#GO:0055029;replication fork#GO:0005657;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 primase#PC00189 DNA replication#P00017>Primase#P00528 IXOSC|EnsemblGenome=LOC115317521|UniProtKB=A0ACM8ENB7 A0ACM8ENB7 LOC115317521 PTHR21567:SF89 CLASP CLIP-ASSOCIATING PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 mitotic sister chromatid segregation#GO:0000070;establishment of spindle localization#GO:0051293;mitotic spindle assembly#GO:0090307;spindle organization#GO:0007051;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;organelle assembly#GO:0070925;organelle localization#GO:0051640;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of mitotic spindle localization#GO:0040001;spindle assembly#GO:0051225;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;establishment of organelle localization#GO:0051656;mitotic spindle organization#GO:0007052;nuclear division#GO:0000280;spindle localization#GO:0051653;cellular localization#GO:0051641 cell cortex#GO:0005938;kinetochore#GO:0000776;cytoplasmic microtubule#GO:0005881;chromosome#GO:0005694;basal part of cell#GO:0045178;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;spindle microtubule#GO:0005876;microtubule#GO:0005874;cell periphery#GO:0071944;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;microtubule organizing center#GO:0005815;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8025465|UniProtKB=A0ACM8DTL1 A0ACM8DTL1 LOC8025465 PTHR48067:SF1 GPI-ANCHOR TRANSAMIDASE GPI-ANCHOR TRANSAMIDASE hydrolase activity#GO:0016787;transferase activity#GO:0016740;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;GPI anchored protein biosynthesis#GO:0180046;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;peptidase complex#GO:1905368;caspase complex#GO:0008303;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8024678|UniProtKB=A0ACM8DVV8 A0ACM8DVV8 sl PTHR10336:SF159 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;transport#GO:0006810;phosphatidylinositol metabolic process#GO:0046488;establishment of localization#GO:0051234;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553;signal transduction#GO:0007165;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;ruffle#GO:0001726;cell projection membrane#GO:0031253 metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 EGF receptor signaling pathway#P00018>PLCgamma#P00556;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;PDGF signaling pathway#P00047>PLCgamma#P01171;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;VEGF signaling pathway#P00056>PLC-gamma#P01414;FGF signaling pathway#P00021>PLCgamma#P00638;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;Angiogenesis#P00005>PLC-gamma#P00256;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Axon guidance mediated by netrin#P00009>Phospholipase C#P00362 IXOSC|EnsemblGenome=LOC8053878|UniProtKB=A0ACM8E1I9 A0ACM8E1I9 LOC8053878 PTHR13498:SF3 SPERM ASSOCIATED ANTIGEN 7 SPERM-ASSOCIATED ANTIGEN 7 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8025821|UniProtKB=A0ACM8DGG4 A0ACM8DGG4 PTHR20961:SF167 GLYCOSYLTRANSFERASE PROTEIN O-LINKED-MANNOSE BETA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8032662|UniProtKB=A0ACM8EXD2 A0ACM8EXD2 LOC8032662 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8028045|UniProtKB=A0ACM8DJK8 A0ACM8DJK8 LOC8028045 PTHR46356:SF1 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115313247|UniProtKB=A0ACM8DST8 A0ACM8DST8 LOC115313247 PTHR10131:SF166 TNF RECEPTOR ASSOCIATED FACTOR RING FINGER PROTEIN 151 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;signal transduction#GO:0007165;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8040491|UniProtKB=A0ACM8DQK8 A0ACM8DQK8 LOC8040491 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8026260|UniProtKB=A0ACM8E148 A0ACM8E148 PTHR19375:SF184 HEAT SHOCK PROTEIN 70KDA STRESS-70 PROTEIN, MITOCHONDRIAL ribonucleoside triphosphate phosphatase activity#GO:0017111;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 iron-sulfur cluster assembly#GO:0016226;protein folding#GO:0006457;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein refolding#GO:0042026;protein metabolic process#GO:0019538;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC8023704|UniProtKB=A0ACM8ED44 A0ACM8ED44 Ssdp PTHR12610:SF12 SINGLE STRANDED DNA BINDING PROTEIN SEQUENCE-SPECIFIC SINGLE-STRANDED DNA-BINDING PROTEIN, ISOFORM D transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8033199|UniProtKB=A0ACM8F1P0 A0ACM8F1P0 LOC8033199 PTHR11534:SF9 MYOGENIC FACTOR MYOGENIC-DETERMINATION PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;positive regulation of developmental process#GO:0051094;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115330199|UniProtKB=A0ACM8EAH0 A0ACM8EAH0 LOC115330199 PTHR47958:SF170 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX42 RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC121833986|UniProtKB=A0ACM8FMH6 A0ACM8FMH6 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030707|UniProtKB=A0ACM8DHF4 A0ACM8DHF4 LOC8030707 PTHR23428:SF70 HISTONE H2B HISTONE H2B chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8023809|UniProtKB=A0ACM8G625 A0ACM8G625 LOC8023809 PTHR13847:SF193 SARCOSINE DEHYDROGENASE-RELATED PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8052255|UniProtKB=A0ACM8EB57 A0ACM8EB57 LOC8052255 PTHR12420:SF50 PHD FINGER PROTEIN LD43541P-RELATED intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115332202|UniProtKB=A0ACM8EDY8 A0ACM8EDY8 LOC115332202 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115310298|UniProtKB=A0ACM8FYX8 A0ACM8FYX8 LOC115310298 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121838181|UniProtKB=A0ACM8G705 A0ACM8G705 LOC121838181 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311241|UniProtKB=A0ACM8EW02 A0ACM8EW02 LOC115312447 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121833543|UniProtKB=A0ACM8FLM0 A0ACM8FLM0 LOC121833543 PTHR12101:SF1 POPEYE DOMAIN CONTAINING PROTEIN BVES ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076 developmental process#GO:0032502;striated muscle cell differentiation#GO:0051146;multicellular organism development#GO:0007275;regulation of membrane potential#GO:0042391;animal organ development#GO:0048513;cellular developmental process#GO:0048869;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;heart development#GO:0007507;multicellular organismal process#GO:0032501;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;tight junction#GO:0070160;sarcolemma#GO:0042383;cell junction#GO:0030054;apical junction complex#GO:0043296 IXOSC|EnsemblGenome=LOC120837200|UniProtKB=A0ACM8EHI1 A0ACM8EHI1 LOC120837200 PTHR23428:SF386 HISTONE H2B HISTONE H2B 1-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8028933|UniProtKB=A0ACM8DHD0 A0ACM8DHD0 LOC8028933 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120840316|UniProtKB=A0ACM8EP56 A0ACM8EP56 LOC120840316 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121836553|UniProtKB=A0ACM8FZ35 A0ACM8FZ35 LOC121836553 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8031515|UniProtKB=A0ACM8ED90 A0ACM8ED90 LOC8031515 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 IXOSC|EnsemblGenome=LOC8037027|UniProtKB=A0ACM8DZ20 A0ACM8DZ20 Klc PTHR45783:SF3 KINESIN LIGHT CHAIN KINESIN LIGHT CHAIN cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156 Alzheimer disease-amyloid secretase pathway#P00003>kinesin#P00107 IXOSC|EnsemblGenome=LOC120836630|UniProtKB=A0ACM8EFG8 A0ACM8EFG8 LOC120836630 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046101|UniProtKB=A0ACM8FE25 A0ACM8FE25 LOC121046101 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8039484|UniProtKB=A0ACM8ED84 A0ACM8ED84 LOC8039484 PTHR11588:SF4 TUBULIN TUBULIN DELTA CHAIN ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 tubulin#PC00228;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8028433|UniProtKB=A0ACM8DGF4 A0ACM8DGF4 LOC8028433 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8029804|UniProtKB=A0ACM8FHE4 A0ACM8FHE4 LOC8029804 PTHR47020:SF1 HILLARIN HILLARIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120845183|UniProtKB=A0ACM8F086 A0ACM8F086 LOC120845183 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC115318289|UniProtKB=A0ACM8DYD9 A0ACM8DYD9 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8031503|UniProtKB=A0ACM8F497 A0ACM8F497 LOC8031503 PTHR23065:SF15 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 AT02057P protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;protein-containing complex organization#GO:0043933;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234 coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;clathrin-coated vesicle#GO:0030136;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8031654|UniProtKB=A0ACM8E9G8 A0ACM8E9G8 Fbw5 PTHR20995:SF17 F-BOX/WD REPEAT-CONTAINING PROTEIN 5 F-BOX_WD REPEAT-CONTAINING PROTEIN 5 IXOSC|EnsemblGenome=LOC8023445|UniProtKB=A0ACM8EEF2 A0ACM8EEF2 LOC8023445 PTHR17537:SF5 TRANSDUCER OF ERBB2 TOB TRANSDUCER OF ERBB2, ISOFORM A transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8024076|UniProtKB=A0ACM8EC78 A0ACM8EC78 LOC8024076 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC8026438|UniProtKB=A0ACM8DSD2 A0ACM8DSD2 LOC8026438 PTHR47385:SF14 CALPONIN TRANSGELIN binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 IXOSC|EnsemblGenome=LOC115326883|UniProtKB=A0ACM8FCX0 A0ACM8FCX0 LOC115326883 PTHR45945:SF3 REGULATOR OF G-PROTEIN SIGNALING LOCO REGULATOR OF G-PROTEIN SIGNALING LOCO enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115318981|UniProtKB=A0ACM8EFC2 A0ACM8EFC2 LOC115318981 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8042894|UniProtKB=A0ACM8E9F2 A0ACM8E9F2 PTHR46406:SF1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 NITRIC OXIDE-ASSOCIATED PROTEIN 1 ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mitochondrial ribosome assembly#GO:0061668;ribosomal small subunit biogenesis#GO:0042274 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8031398|UniProtKB=A0ACM8DX07 A0ACM8DX07 LOC8031398 PTHR15497:SF1 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE 3-HYDROXYANTHRANILATE 3,4-DIOXYGENASE oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115330970|UniProtKB=A0ACM8EBG8 A0ACM8EBG8 LOC115330970 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842050|UniProtKB=A0ACM8ESZ5 A0ACM8ESZ5 LOC120842050 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030871|UniProtKB=A0ACM8EBZ9 A0ACM8EBZ9 PTHR10046:SF24 ATP DEPENDENT LON PROTEASE FAMILY MEMBER LON PROTEASE HOMOLOG 2, PEROXISOMAL catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;establishment of protein localization#GO:0045184;protein metabolic process#GO:0019538;localization#GO:0051179;proteolysis#GO:0006508;protein targeting#GO:0006605;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8039230|UniProtKB=A0ACM8DTH6 A0ACM8DTH6 LOC8039230 PTHR24060:SF179 METABOTROPIC GLUTAMATE RECEPTOR MANGETOUT, ISOFORM G molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;transmembrane signaling receptor activity#GO:0004888 regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8043024|UniProtKB=A0ACM8EZ20 A0ACM8EZ20 LOC8043024 PTHR44054:SF4 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE ENOYL REDUCTASE (ER) DOMAIN-CONTAINING PROTEIN Huntington disease#P00029>PIG3#G01535 IXOSC|EnsemblGenome=LOC8038149|UniProtKB=A0ACM8DGM4 A0ACM8DGM4 pch2 PTHR45991:SF1 PACHYTENE CHECKPOINT PROTEIN 2 PACHYTENE CHECKPOINT PROTEIN 2 HOMOLOG sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;intracellular signal transduction#GO:0035556;organelle fission#GO:0048285;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;negative regulation of organelle organization#GO:0010639;primary metabolic process#GO:0044238;negative regulation of cellular component organization#GO:0051129;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;reproductive process#GO:0022414;homologous recombination#GO:0035825;regulation of cellular process#GO:0050794;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of reproductive process#GO:2000241;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of meiotic cell cycle#GO:0051445;regulation of biological process#GO:0050789;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120840944|UniProtKB=A0ACM8EQP6 A0ACM8EQP6 LOC120840944 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8027100|UniProtKB=A0ACM8E4Z5 A0ACM8E4Z5 LOC8027100 PTHR11306:SF0 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED LP08842P-RELATED lipid binding#GO:0008289;steroid binding#GO:0005496;sterol binding#GO:0032934;binding#GO:0005488 organic hydroxy compound transport#GO:0015850;sterol transport#GO:0015918;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 IXOSC|EnsemblGenome=LOC115322053|UniProtKB=A0ACM8E1N1 A0ACM8E1N1 ND-13B PTHR12653:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-B SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 5 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;metabolic process#GO:0008152;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120847905|UniProtKB=A0ACM8F557 A0ACM8F557 LOC120847905 PTHR33064:SF47 POL PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841418|UniProtKB=A0ACM8ERH0 A0ACM8ERH0 LOC120841418 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115322205|UniProtKB=A0ACM8E2G2 A0ACM8E2G2 LOC115322205 PTHR13349:SF2 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 TRANSLATION MACHINERY-ASSOCIATED PROTEIN 16 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120838882|UniProtKB=A0ACM8ELU1 A0ACM8ELU1 LOC120838882 PTHR48575:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842278|UniProtKB=A0ACM8FNZ4 A0ACM8FNZ4 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8023702|UniProtKB=A0ACM8DHE8 A0ACM8DHE8 Dph5 PTHR10882:SF0 DIPHTHINE SYNTHASE DIPHTHINE METHYL ESTER SYNTHASE methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8041736|UniProtKB=A0ACM8E3U3 A0ACM8E3U3 Hrb27C PTHR48032:SF23 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 DAZ ASSOCIATED PROTEIN 1 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8035413|UniProtKB=A0ACM8F3V6 A0ACM8F3V6 LOC8035413 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8041786|UniProtKB=A0ACM8E9N7 A0ACM8E9N7 LOC8041786 PTHR16022:SF0 WD REPEAT DOMAIN 60 CYTOPLASMIC DYNEIN 2 INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;spindle pole#GO:0000922;dynein complex#GO:0030286;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630 IXOSC|EnsemblGenome=LOC8053184|UniProtKB=A0ACM8DR81 A0ACM8DR81 LOC8053184 PTHR28309:SF1 REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN REQUIRED FOR EXCISION 1-B DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052824|UniProtKB=A0ACM8F5B8 A0ACM8F5B8 LOC8052824 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8035323|UniProtKB=A0ACM8DJS5 A0ACM8DJS5 LOC8035323 PTHR10221:SF9 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058 membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP#P00670;General transcription regulation#P00023>TBP-associated factors#P00658 IXOSC|EnsemblGenome=LOC120844770|UniProtKB=A0ACM8EZ75 A0ACM8EZ75 rept PTHR11093:SF2 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 2 macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;protein-RNA complex organization#GO:0071826;ribonucleoprotein complex biogenesis#GO:0022613;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;protein-RNA complex assembly#GO:0022618;regulation of DNA-templated transcription#GO:0006355 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120840049|UniProtKB=A0ACM8EN54 A0ACM8EN54 LOC120840049 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115325502|UniProtKB=A0ACM8F2Q4 A0ACM8F2Q4 LOC120847496 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8035408|UniProtKB=A0ACM8E2V7 A0ACM8E2V7 LOC8035408 PTHR24056:SF0 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 7 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cellular process#GO:0050794;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;regulation of cell cycle#GO:0051726;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366 transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120837559|UniProtKB=A0ACM8EIP7 A0ACM8EIP7 LOC120837559 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;heart development#GO:0007507;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC120838917|UniProtKB=A0ACM8ELM9 A0ACM8ELM9 LOC120838917 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8032365|UniProtKB=A0ACM8DJF2 A0ACM8DJF2 LOC8032365 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE response to stress#GO:0006950;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;protein folding#GO:0006457;protein metabolic process#GO:0019538;protein refolding#GO:0042026 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC8039636|UniProtKB=A0ACM8DZS3 A0ACM8DZS3 LOC8039636 PTHR24252:SF41 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11D-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115311528|UniProtKB=A0ACM8FHV4 A0ACM8FHV4 LOC115311528 PTHR19300:SF66 BETA-1,4-GALACTOSYLTRANSFERASE BETA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE A catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 biosynthetic process#GO:0009058;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121838247|UniProtKB=A0ACM8G6Z5 A0ACM8G6Z5 LOC121838247 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120841555|UniProtKB=A0ACM8ERW1 A0ACM8ERW1 LOC120841555 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;DNA binding#GO:0003677 DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;transferase complex#GO:1990234;membraneless organelle#GO:0043228;site of double-strand break#GO:0035861;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120841411|UniProtKB=A0ACM8ER67 A0ACM8ER67 LOC120841411 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120844851|UniProtKB=A0ACM8EZY5 A0ACM8EZY5 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038244|UniProtKB=A0ACM8F290 A0ACM8F290 LOC8038244 PTHR24351:SF209 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to oxygen-containing compound#GO:1901700;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to nitrogen compound#GO:1901698;response to peptide hormone#GO:0043434 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115328815|UniProtKB=A0ACM8E8Q9 A0ACM8E8Q9 LOC115328815 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8036203|UniProtKB=A0ACM8DJY2 A0ACM8DJY2 LOC8036203 PTHR12320:SF98 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE PTC7 HOMOLOG regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC120850229|UniProtKB=A0ACM8F9J7 A0ACM8F9J7 LOC120850229 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115321786|UniProtKB=A0ACM8E214 A0ACM8E214 LOC115321786 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC120844744|UniProtKB=A0ACM8EZK2 A0ACM8EZK2 LOC120844744 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8051279|UniProtKB=A0ACM8DW81 A0ACM8DW81 LOC8051279 PTHR15696:SF5 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG7 DNA binding#GO:0003677;RNA binding#GO:0003723;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121048176|UniProtKB=A0ACM8FHT4 A0ACM8FHT4 LOC121048176 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC115326830|UniProtKB=A0ACM8E6F5 A0ACM8E6F5 LOC115326830 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8039536|UniProtKB=A0ACM8E3Z8 A0ACM8E3Z8 Arpc4 PTHR22629:SF0 ARP2/3 COMPLEX 20 KD SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 4 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511 IXOSC|EnsemblGenome=LOC8025515|UniProtKB=A0ACM8DYX9 A0ACM8DYX9 LOC8025515 PTHR43329:SF141 EPOXIDE HYDROLASE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN-RELATED ether hydrolase activity#GO:0016803;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8044016|UniProtKB=A0ACM8ELN4 A0ACM8ELN4 LOC8044016 PTHR14387:SF0 THADA/DEATH RECEPTOR INTERACTING PROTEIN DUF2428 DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121833409|UniProtKB=A0ACM8FKU7 A0ACM8FKU7 LOC121833409 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC120844709|UniProtKB=A0ACM8F0H1 A0ACM8F0H1 LOC120844709 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC121047598|UniProtKB=A0ACM8FGF3 A0ACM8FGF3 LOC121047598 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115315237|UniProtKB=A0ACM8F0L2 A0ACM8F0L2 LOC115315237 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8034690|UniProtKB=A0ACM8DJK2 A0ACM8DJK2 LOC8034690 PTHR45962:SF7 N-FATTY-ACYL-AMINO ACID SYNTHASE/HYDROLASE PM20D1 N-FATTY-ACYL-AMINO ACID SYNTHASE_HYDROLASE PM20D1.1-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8053687|UniProtKB=A0ACM8EEQ7 A0ACM8EEQ7 LOC8053687 PTHR24070:SF290 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE, FAMILY 10, MEMBER A catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120840902|UniProtKB=A0ACM8EQJ9 A0ACM8EQJ9 LOC120840902 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558 reductase#PC00198 IXOSC|EnsemblGenome=LOC8028339|UniProtKB=A0ACM8FYE6 A0ACM8FYE6 LOC8028339 PTHR11269:SF16 PERIOD CIRCADIAN PROTEIN PERIOD CIRCADIAN PROTEIN transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;protein binding#GO:0005515;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription factor binding#GO:0008134;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;response to radiation#GO:0009314;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;photoperiodism#GO:0009648;negative regulation of cellular process#GO:0048523;response to external stimulus#GO:0009605;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;circadian regulation of gene expression#GO:0032922;response to abiotic stimulus#GO:0009628;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;rhythmic process#GO:0048511;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217 Circadian clock system#P00015>Per#P00504;Circadian clock system#P00015>per#G01499;Circadian clock system#P00015>per#G01503 IXOSC|EnsemblGenome=LOC120839485|UniProtKB=A0ACM8FMF5 A0ACM8FMF5 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120846317|UniProtKB=A0ACM8F223 A0ACM8F223 LOC120846317 PTHR11439:SF463 GAG-POL-RELATED RETROTRANSPOSON INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8035401|UniProtKB=A0ACM8FH76 A0ACM8FH76 LOC8035401 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120849539|UniProtKB=A0ACM8FIG4 A0ACM8FIG4 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8027510|UniProtKB=A0ACM8FI95 A0ACM8FI95 LOC8027510 PTHR43564:SF2 KYNURENINE FORMAMIDASE-LIKE PROTEIN BLR6059 PROTEIN IXOSC|EnsemblGenome=LOC120848141|UniProtKB=A0ACM8F5A5 A0ACM8F5A5 LOC120848141 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051127|UniProtKB=A0ACM8FC11 A0ACM8FC11 LOC8051127 PTHR10865:SF28 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN ELM2 DOMAIN-CONTAINING PROTEIN transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899;protein binding#GO:0005515;histone deacetylase binding#GO:0042826 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8037220|UniProtKB=A0ACM8DI00 A0ACM8DI00 Nup37 PTHR22806:SF0 NUCLEOPORIN NUP37 P37 -RELATED NUCLEOPORIN NUP37 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC120836293|UniProtKB=A0ACM8EI43 A0ACM8EI43 LOC120836293 PTHR23042:SF107 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS FI10506P-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120841081|UniProtKB=A0ACM8ERW4 A0ACM8ERW4 LOC120841081 PTHR12411:SF917 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L, LIKE-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120842464|UniProtKB=A0ACM8ETP2 A0ACM8ETP2 LOC120842464 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031606|UniProtKB=A0ACM8DW98 A0ACM8DW98 LOC8031606 PTHR10953:SF3 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7 sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;Atg12 activating enzyme activity#GO:0019778;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874 organelle assembly#GO:0070925;vacuole organization#GO:0007033;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;primary metabolic process#GO:0044238;protein modification process#GO:0036211;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;autophagy of mitochondrion#GO:0000422;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;response to nutrient levels#GO:0031667;post-translational protein modification#GO:0043687;macroautophagy#GO:0016236;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;process utilizing autophagic mechanism#GO:0061919;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;response to stimulus#GO:0050896;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;cellular component assembly#GO:0022607 phagophore assembly site#GO:0000407;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 IXOSC|EnsemblGenome=LOC121047851|UniProtKB=A0ACM8FSD8 A0ACM8FSD8 LOC121047851 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8032769|UniProtKB=A0ACM8DGT1 A0ACM8DGT1 LOC8032769 PTHR46517:SF1 FRUCTOSE-2,6-BISPHOSPHATASE TIGAR FRUCTOSE-2,6-BISPHOSPHATASE TIGAR phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 regulation of carbohydrate metabolic process#GO:0006109;negative regulation of cellular process#GO:0048523;negative regulation of catabolic process#GO:0009895;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 Cobalamin biosynthesis#P02735>Ribazole-5-phosphate phosphatase#P02881 IXOSC|EnsemblGenome=LOC120850624|UniProtKB=A0ACM8FLB6 A0ACM8FLB6 LOC120850624 PTHR22780:SF13 ADAPTIN, ALPHA/GAMMA/EPSILON AP-4 COMPLEX SUBUNIT EPSILON-1 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;membrane coat#GO:0030117;coated membrane#GO:0048475 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8035080|UniProtKB=A0ACM8E9Q1 A0ACM8E9Q1 LOC8035080 PTHR11444:SF1 ASPARTATEAMMONIA/ARGININOSUCCINATE/ADENYLOSUCCINATE LYASE FUMARATE HYDRATASE, MITOCHONDRIAL carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 tricarboxylic acid cycle#GO:0006099;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 lyase#PC00144 TCA cycle#P00051>Fumarase#P01271 IXOSC|EnsemblGenome=LOC8035905|UniProtKB=A0ACM8FLK1 A0ACM8FLK1 LOC8035905 PTHR45635:SF14 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;purine nucleotide transmembrane transporter activity#GO:0015216;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297 carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;biological regulation#GO:0065007;regulation of mitochondrial membrane permeability#GO:0046902;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;regulation of membrane permeability#GO:0090559;transport#GO:0006810;regulation of biological quality#GO:0065008;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121837143|UniProtKB=A0ACM8G2G4 A0ACM8G2G4 LOC121837143 PTHR11851:SF229 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104 intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endopeptidase complex#GO:1905369;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8024881|UniProtKB=A0ACM8EB52 A0ACM8EB52 LOC8024881 PTHR35270:SF3 FUSELESS, ISOFORM A FUSELESS, ISOFORM A developmental maturation#GO:0021700;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;nervous system development#GO:0007399;synaptic signaling#GO:0099536;cellular process#GO:0009987;cell maturation#GO:0048469;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuromuscular synaptic transmission#GO:0007274;developmental process#GO:0032502;neuron differentiation#GO:0030182;anterograde trans-synaptic signaling#GO:0098916;cell differentiation#GO:0030154;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anatomical structure maturation#GO:0071695;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;trans-synaptic signaling#GO:0099537;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8051156|UniProtKB=A0ACM8FD29 A0ACM8FD29 LOC8051156 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8032344|UniProtKB=A0ACM8E4J7 A0ACM8E4J7 LOC8032344 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8023227|UniProtKB=A0ACM8EJ52 A0ACM8EJ52 LOC8023227 PTHR21358:SF4 PROTEIN MAELSTROM HOMOLOG PROTEIN MAELSTROM HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 meiotic nuclear division#GO:0140013;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;spermatogenesis#GO:0007283;developmental process#GO:0032502;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;organelle fission#GO:0048285;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;negative regulation of transcription by RNA polymerase II#GO:0000122;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;developmental process involved in reproduction#GO:0003006;cell cycle#GO:0007049;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;gene expression#GO:0010467;male meiotic nuclear division#GO:0007140;RNA processing#GO:0006396;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;RNA metabolic process#GO:0016070;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;nuclear division#GO:0000280;nucleic acid biosynthetic process#GO:0141187;gamete generation#GO:0007276;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;meiotic cell cycle process#GO:1903046;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8029170|UniProtKB=A0ACM8DHQ4 A0ACM8DHQ4 LOC8029170 PTHR10334:SF615 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8026283|UniProtKB=A0ACM8FF08 A0ACM8FF08 Secp43 PTHR37457:SF3 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED TRNA SELENOCYSTEINE-ASSOCIATED PROTEIN 1 IXOSC|EnsemblGenome=LOC8030407|UniProtKB=A0ACM8DH11 A0ACM8DH11 LOC8030407 PTHR24056:SF598 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 mitotic cell cycle phase transition#GO:0044772;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cell cycle#GO:0007049;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;mitotic cell cycle process#GO:1903047;cellular process#GO:0009987;cell cycle G2/M phase transition#GO:0044839;signal transduction#GO:0007165;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway feedback loops 2#P04398>cdk2#P04653;p53 pathway#P00059>Cdk2#P04625;p53 pathway#P00059>Cdc2#P04634 IXOSC|EnsemblGenome=LOC8025159|UniProtKB=A0ACM8DPG3 A0ACM8DPG3 Gnptab PTHR24045:SF0 FAMILY NOT NAMED FI02838P macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115310242|UniProtKB=A0ACM8DPJ1 A0ACM8DPJ1 LOC115310242 PTHR12460:SF40 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN REGULATION OF NUCLEAR PRE-MRNA DOMAIN-CONTAINING PROTEIN 2 RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488 metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8033906|UniProtKB=A0ACM8DZV1 A0ACM8DZV1 LOC8033906 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121047238|UniProtKB=A0ACM8FG10 A0ACM8FG10 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115328743|UniProtKB=A0ACM8FX44 A0ACM8FX44 LOC115328743 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8030701|UniProtKB=A0ACM8DUA1 A0ACM8DUA1 Vps13B PTHR12517:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13B INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13B membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115325999|UniProtKB=A0ACM8E5C5 A0ACM8E5C5 LOC115325999 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8050817|UniProtKB=A0ACM8E6P3 A0ACM8E6P3 LOC8050817 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121832987|UniProtKB=A0ACM8FTJ6 A0ACM8FTJ6 LOC121832987 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8052322|UniProtKB=A0ACM8E3Y3 A0ACM8E3Y3 LOC8052322 PTHR46199:SF3 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cell division#GO:0051301;cellular response to stimulus#GO:0051716;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;organelle assembly#GO:0070925;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;signaling#GO:0023052;mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of biological process#GO:0050789;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;Rho protein signal transduction#GO:0007266;cytoskeleton-dependent cytokinesis#GO:0061640;nuclear division#GO:0000280;cytokinesis#GO:0000910;intracellular signaling cassette#GO:0141124;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;signal transduction#GO:0007165;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;intracellular organelle#GO:0043229;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;midbody#GO:0030496;intracellular protein-containing complex#GO:0140535;cleavage furrow#GO:0032154;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;cell division site#GO:0032153;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020 G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC115317273|UniProtKB=A0ACM8DX09 A0ACM8DX09 LOC115317273 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115320807|UniProtKB=A0ACM8F9E6 A0ACM8F9E6 LOC115320807 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8034447|UniProtKB=A0ACM8G1Y8 A0ACM8G1Y8 LOC8034447 PTHR46831:SF1 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 19 membrane#GO:0016020;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8033658|UniProtKB=A0ACM8EU39 A0ACM8EU39 LOC8033658 PTHR47969:SF33 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED KINESIN-LIKE PROTEIN cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC120849948|UniProtKB=A0ACM8F8R2 A0ACM8F8R2 LOC120849948 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT AT04468P-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;export from cell#GO:0140352;homeostatic process#GO:0042592;metal ion transport#GO:0030001;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC120849790|UniProtKB=A0ACM8G772 A0ACM8G772 LOC120849790 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115311625|UniProtKB=A0ACM8DRB1 A0ACM8DRB1 clu PTHR12601:SF54 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3 CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle localization#GO:0051640;mitochondrion localization#GO:0051646;localization#GO:0051179 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC115315900|UniProtKB=A0ACM8F5Z3 A0ACM8F5Z3 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034750|UniProtKB=A0ACM8E6D3 A0ACM8E6D3 LOC8034750 PTHR16220:SF1 WD REPEAT PROTEIN 8-RELATED WD REPEAT-CONTAINING PROTEIN WRAP73 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;microtubule-based process#GO:0007017;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;nuclear division#GO:0000280;organelle assembly#GO:0070925 centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8036715|UniProtKB=A0ACM8EBH0 A0ACM8EBH0 LOC8036715 PTHR48030:SF7 SPLICING FACTOR 3B SUBUNIT 4 SPLICING FACTOR 3B SUBUNIT 4 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8024568|UniProtKB=A0ACM8DIF0 A0ACM8DIF0 LOC8024568 PTHR11679:SF85 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33A vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole#GO:0000323;vesicle tethering complex#GO:0099023;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC121045697|UniProtKB=A0ACM8FCW0 A0ACM8FCW0 LOC121045697 PTHR10283:SF136 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2-LIKE ISOFORM X1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8031582|UniProtKB=A0ACM8DIE7 A0ACM8DIE7 LOC8031582 PTHR23505:SF79 SPINSTER PROTEIN SPINSTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120847473|UniProtKB=A0ACM8F397 A0ACM8F397 LOC120847473 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER FI24011P1-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115317224|UniProtKB=A0ACM8FAN4 A0ACM8FAN4 LOC115317224 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8028390|UniProtKB=A0ACM8F0E7 A0ACM8F0E7 LOC8028390 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115313250|UniProtKB=A0ACM8DSL4 A0ACM8DSL4 LOC115313250 PTHR10131:SF166 TNF RECEPTOR ASSOCIATED FACTOR RING FINGER PROTEIN 151 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8028801|UniProtKB=A0ACM8DVU1 A0ACM8DVU1 Nup58 PTHR13437:SF2 NUCLEOPORIN P58/P45 NUCLEOPORIN-LIKE PROTEIN 1 NUCLEOPORIN P58_P45 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nuclear transport#GO:0051169;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 IXOSC|EnsemblGenome=LOC8050498|UniProtKB=A0ACM8EV34 A0ACM8EV34 Arp6 PTHR11937:SF47 ACTIN ACTIN-RELATED PROTEIN 6 chromatin binding#GO:0003682;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;protein-containing complex binding#GO:0044877;structural molecule activity#GO:0005198;nucleosome binding#GO:0031491 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;nucleolus organization#GO:0007000;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 actin and actin related protein#PC00039 IXOSC|EnsemblGenome=LOC120849469|UniProtKB=A0ACM8FXI9 A0ACM8FXI9 LOC120849469 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332943|UniProtKB=A0ACM8EDT0 A0ACM8EDT0 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120837560|UniProtKB=A0ACM8EID9 A0ACM8EID9 LOC120837560 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8039228|UniProtKB=A0ACM8E5J7 A0ACM8E5J7 LOC8039228 PTHR43595:SF2 37S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS42 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115327578|UniProtKB=A0ACM8FJS8 A0ACM8FJS8 LOC115327578 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121838096|UniProtKB=A0ACM8G6E8 A0ACM8G6E8 LOC121838096 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038371|UniProtKB=A0ACM8FKS8 A0ACM8FKS8 LOC8038371 PTHR23196:SF42 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN PAX-INTERACTING PROTEIN 1 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stress#GO:0006950;response to stimulus#GO:0050896 histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8051765|UniProtKB=A0ACM8DX71 A0ACM8DX71 RpL27 PTHR10497:SF0 60S RIBOSOMAL PROTEIN L27 LARGE RIBOSOMAL SUBUNIT PROTEIN EL27 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8044043|UniProtKB=A0ACM8DN07 A0ACM8DN07 Ehbp1 PTHR23167:SF97 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED EPS15 HOMOLOGY DOMAIN CONTAINING PROTEIN-BINDING PROTEIN 1, ISOFORM F organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8029910|UniProtKB=A0ACM8EIW0 A0ACM8EIW0 LOC8029910 PTHR18884:SF137 SEPTIN SEPTIN-7 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cell cycle#GO:0007049;macromolecule localization#GO:0033036;cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402;cytokinesis#GO:0000910;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8051616|UniProtKB=A0ACM8F8K3 A0ACM8F8K3 LOC8051616 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE lipase activity#GO:0016298;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 organophosphate catabolic process#GO:0046434;ceramide metabolic process#GO:0006672;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764 hydrolase#PC00121;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC8044077|UniProtKB=A0ACM8DL69 A0ACM8DL69 alphaSnap PTHR13768:SF8 SOLUBLE NSF ATTACHMENT PROTEIN SNAP ALPHA-SOLUBLE NSF ATTACHMENT PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;cellular localization#GO:0051641;cellular component disassembly#GO:0022411;localization#GO:0051179;protein transport#GO:0015031 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115312677|UniProtKB=A0ACM8EYJ7 A0ACM8EYJ7 LOC115312677 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120847396|UniProtKB=A0ACM8F3Y5 A0ACM8F3Y5 LOC120847396 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8041986|UniProtKB=A0ACM8EYI1 A0ACM8EYI1 LOC8041986 PTHR24056:SF334 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 1 cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173 cellular process#GO:0009987;signal transduction#GO:0007165;cell cycle G2/M phase transition#GO:0044839;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;cell cycle process#GO:0022402;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;mitotic cell cycle phase transition#GO:0044772;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Cdc2#P04634 IXOSC|EnsemblGenome=LOC8036672|UniProtKB=A0ACM8E2V2 A0ACM8E2V2 LOC8036672 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041324|UniProtKB=A0ACM8DKN6 A0ACM8DKN6 LOC8041324 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115333099|UniProtKB=A0ACM8EEI2 A0ACM8EEI2 LOC115333099 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8034368|UniProtKB=A0ACM8DJ79 A0ACM8DJ79 PTHR12121:SF37 CARBON CATABOLITE REPRESSOR PROTEIN 4 2',5'-PHOSPHODIESTERASE 12 catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC8043662|UniProtKB=A0ACM8DWB5 A0ACM8DWB5 LOC8043662 PTHR13817:SF80 TITIN INACTIVE TYROSINE-PROTEIN KINASE 7 structural protein#PC00211 IXOSC|EnsemblGenome=LOC121835025|UniProtKB=A0ACM8FSH7 A0ACM8FSH7 LOC121835025 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8035952|UniProtKB=A0ACM8G000 A0ACM8G000 LOC8035952 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8038365|UniProtKB=A0ACM8E907 A0ACM8E907 LOC8038365 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC120842725|UniProtKB=A0ACM8G759 A0ACM8G759 LOC120842725 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC120847487|UniProtKB=A0ACM8F530 A0ACM8F530 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837833|UniProtKB=A0ACM8G6D5 A0ACM8G6D5 LOC121837833 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115320387|UniProtKB=A0ACM8EQS3 A0ACM8EQS3 LOC115320387 PTHR18884:SF137 SEPTIN SEPTIN-7 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cell cycle process#GO:0022402;cellular process#GO:0009987;cell division#GO:0051301;cell cycle#GO:0007049;macromolecule localization#GO:0033036;cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179 cell cortex#GO:0005938;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC115328052|UniProtKB=A0ACM8G2G7 A0ACM8G2G7 LOC115328052 PTHR45620:SF44 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTOR, ORPHAN-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8023286|UniProtKB=A0ACM8EAK3 A0ACM8EAK3 LOC8023286 PTHR10969:SF101 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED 63 KDA SPERM FLAGELLAR MEMBRANE PROTEIN protein binding#GO:0005515;lipid binding#GO:0008289;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;phospholipid binding#GO:0005543;enzyme binding#GO:0019899 catabolic process#GO:0009056;response to stimulus#GO:0050896;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;cellular component disassembly#GO:0022411;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;cellular response to nutrient levels#GO:0031669 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;autophagosome#GO:0005776;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8026329|UniProtKB=A0ACM8DHM7 A0ACM8DHM7 LOC8026329 PTHR12125:SF5 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8030847|UniProtKB=A0ACM8DHL1 A0ACM8DHL1 LOC8030847 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC115314240|UniProtKB=A0ACM8EXZ9 A0ACM8EXZ9 LOC115314240 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8040136|UniProtKB=A0ACM8DKI8 A0ACM8DKI8 asun PTHR12955:SF1 SARCOMA ANTIGEN NY-SAR-95-RELATED INTEGRATOR COMPLEX SUBUNIT 13 localization#GO:0051179;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;centrosome localization#GO:0051642;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;integrator complex#GO:0032039 IXOSC|EnsemblGenome=LOC115308719|UniProtKB=A0ACM8G560 A0ACM8G560 LOC115308719 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120841466|UniProtKB=A0ACM8ERS3 A0ACM8ERS3 eIF2alpha PTHR10602:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 1 ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;translation initiation factor activity#GO:0003743;protein-containing complex binding#GO:0044877;binding#GO:0005488;translation factor activity#GO:0180051 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224;translation factor#PC00223 Apoptosis signaling pathway#P00006>ELF2alpha#P00307 IXOSC|EnsemblGenome=LOC120840847|UniProtKB=A0ACM8G2L4 A0ACM8G2L4 LOC120840847 PTHR46925:SF2 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED G PROTEIN-COUPLED RECEPTOR TKR-1-RELATED neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120842249|UniProtKB=A0ACM8ETD0 A0ACM8ETD0 LOC120842249 PTHR24412:SF450 KELCH PROTEIN KELCH REPEAT AND BTB DOMAIN-CONTAINING PROTEIN F47D12.7-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120848270|UniProtKB=A0ACM8G8I8 A0ACM8G8I8 LOC120848270 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841863|UniProtKB=A0ACM8ESP0 A0ACM8ESP0 LOC120841863 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 lipid transport#GO:0006869;macromolecule localization#GO:0033036;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;cellular process#GO:0009987;establishment of localization#GO:0051234;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;transport#GO:0006810;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;carbohydrate derivative catabolic process#GO:1901136;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;localization#GO:0051179;ceramide metabolic process#GO:0006672;lipid localization#GO:0010876 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121836343|UniProtKB=A0ACM8FYE3 A0ACM8FYE3 LOC121836343 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8027278|UniProtKB=A0ACM8EHC9 A0ACM8EHC9 LOC8027278 PTHR45702:SF3 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;proteolysis#GO:0006508;cell communication#GO:0007154;protein metabolic process#GO:0019538;membrane protein proteolysis#GO:0033619;signal transduction#GO:0007165;cellular process#GO:0009987;membrane protein ectodomain proteolysis#GO:0006509;biological regulation#GO:0065007;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 IXOSC|EnsemblGenome=LOC8039158|UniProtKB=A0ACM8EYG6 A0ACM8EYG6 LOC8039158 PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC115316154|UniProtKB=A0ACM8ENP6 A0ACM8ENP6 LOC115316154 PTHR33620:SF1 UREASE ACCESSORY PROTEIN F UREASE ACCESSORY PROTEIN F IXOSC|EnsemblGenome=LOC8023337|UniProtKB=A0ACM8DGT9 A0ACM8DGT9 Sys1 PTHR12952:SF0 SYS1 PROTEIN SYS1 HOMOLOG macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to Golgi apparatus#GO:0034067;protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to endosome transport#GO:0006895;Golgi to plasma membrane transport#GO:0006893;protein localization to organelle#GO:0033365;cytosolic transport#GO:0016482;Golgi to plasma membrane protein transport#GO:0043001;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115317635|UniProtKB=A0ACM8DX62 A0ACM8DX62 LOC115317635 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052623|UniProtKB=A0ACM8G567 A0ACM8G567 LOC8052623 PTHR12864:SF89 RAN BINDING PROTEIN 9-RELATED SPRY DOMAIN-CONTAINING PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121837092|UniProtKB=A0ACM8G239 A0ACM8G239 LOC121837092 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843457|UniProtKB=A0ACM8EW67 A0ACM8EW67 LOC120843457 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025853|UniProtKB=A0ACM8EEW5 A0ACM8EEW5 LOC8025853 PTHR34651:SF1 SIMILAR TO ENSANGP00000021391 SIMILAR TO HUMAN CHROMOSOME 15 OPEN READING FRAME 61 IXOSC|EnsemblGenome=LOC8035846|UniProtKB=A0ACM8DJV5 A0ACM8DJV5 LOC8035846 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121837333|UniProtKB=A0ACM8G381 A0ACM8G381 LOC121837333 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315203|UniProtKB=A0ACM8EN75 A0ACM8EN75 LOC115315203 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120837448|UniProtKB=A0ACM8EGY4 A0ACM8EGY4 LOC120837448 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120839201|UniProtKB=A0ACM8EM68 A0ACM8EM68 LOC120839201 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310094|UniProtKB=A0ACM8FLZ4 A0ACM8FLZ4 LOC115310094 PTHR10579:SF178 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-LIKE ion channel#PC00133 IXOSC|EnsemblGenome=LOC121833719|UniProtKB=A0ACM8FMI5 A0ACM8FMI5 LOC121833719 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115323587|UniProtKB=A0ACM8E4D0 A0ACM8E4D0 PolE4 PTHR10252:SF79 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DNA POLYMERASE EPSILON SUBUNIT 4 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987 transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;epsilon DNA polymerase complex#GO:0008622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121833590|UniProtKB=A0ACM8FLS1 A0ACM8FLS1 LOC121833590 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836144|UniProtKB=A0ACM8G591 A0ACM8G591 LOC120836144 PTHR14196:SF17 ODD-SKIPPED - RELATED SUBFAMILY NOT NAMED zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115309510|UniProtKB=A0ACM8DNQ9 A0ACM8DNQ9 LOC115309510 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8028228|UniProtKB=A0ACM8F772 A0ACM8F772 LOC8028228 PTHR43651:SF15 1,4-ALPHA-GLUCAN-BRANCHING ENZYME 1,4-ALPHA-GLUCAN-BRANCHING ENZYME hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;glycogen biosynthetic process#GO:0005978;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;energy reserve metabolic process#GO:0006112;polysaccharide biosynthetic process#GO:0000271;glucan biosynthetic process#GO:0009250;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 amylase#PC00048 IXOSC|EnsemblGenome=LOC8034121|UniProtKB=A0ACM8DIZ0 A0ACM8DIZ0 LOC8034121 PTHR10894:SF1 NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58 NUCLEOLAR PROTEIN 58 nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;binding#GO:0005488;RNA binding#GO:0003723 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115322545|UniProtKB=A0ACM8FMB7 A0ACM8FMB7 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8028824|UniProtKB=A0ACM8DT54 A0ACM8DT54 LOC8028824 PTHR23189:SF102 RNA RECOGNITION MOTIF-CONTAINING PROTEIN NO-ON-TRANSIENT A binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8038217|UniProtKB=A0ACM8EVX4 A0ACM8EVX4 LOC8038217 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395 steroid metabolic process#GO:0008202;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8050805|UniProtKB=A0ACM8DPV5 A0ACM8DPV5 Vang PTHR20886:SF11 VANG-LIKE PROTEIN VANG-LIKE PROTEIN morphogenesis of an epithelium#GO:0002009;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;tissue development#GO:0009888;epithelium development#GO:0060429;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;anatomical structure development#GO:0048856;cell communication#GO:0007154;tissue morphogenesis#GO:0048729;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;signaling#GO:0023052;non-canonical Wnt signaling pathway#GO:0035567;cellular response to stimulus#GO:0051716;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120839259|UniProtKB=A0ACM8G0D1 A0ACM8G0D1 Spt3 PTHR11380:SF16 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION PROTEIN SPT3 HOMOLOG transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC120838015|UniProtKB=A0ACM8EIW3 A0ACM8EIW3 LOC120838015 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120843178|UniProtKB=A0ACM8EVA9 A0ACM8EVA9 LOC120843178 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115312556|UniProtKB=A0ACM8DRV4 A0ACM8DRV4 LOC115312556 PTHR10339:SF32 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 transferase#PC00220 IXOSC|EnsemblGenome=LOC121837061|UniProtKB=A0ACM8G1X1 A0ACM8G1X1 LOC121837061 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC8029984|UniProtKB=A0ACM8EAF4 A0ACM8EAF4 Sec10 PTHR12100:SF0 SEC10 EXOCYST COMPLEX COMPONENT 5 cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;transport#GO:0006810;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;exocytosis#GO:0006887;secretion by cell#GO:0032940 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;cell periphery#GO:0071944;cell cortex#GO:0005938;cytoplasm#GO:0005737;exocyst#GO:0000145;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8041340|UniProtKB=A0ACM8DKL3 A0ACM8DKL3 LOC8041340 PTHR13557:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 COILED-COIL DOMAIN-CONTAINING PROTEIN 86 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8051812|UniProtKB=A0ACM8E7J1 A0ACM8E7J1 LOC8051812 PTHR23049:SF71 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8026620|UniProtKB=A0ACM8G1C5 A0ACM8G1C5 Ask1 PTHR11584:SF369 SERINE/THREONINE PROTEIN KINASE APOPTOTIC SIGNAL-REGULATING KINASE 1, ISOFORM C protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;p38MAPK cascade#GO:0038066;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MEKK1-5#P00553;FGF signaling pathway#P00021>MEKK1-5#P00634 IXOSC|EnsemblGenome=LOC121837257|UniProtKB=A0ACM8G2Z5 A0ACM8G2Z5 LOC121837257 PTHR46925:SF2 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED G PROTEIN-COUPLED RECEPTOR TKR-1-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8039677|UniProtKB=A0ACM8DS83 A0ACM8DS83 LOC8039677 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121046459|UniProtKB=A0ACM8FDY4 A0ACM8FDY4 LOC121046459 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850583|UniProtKB=A0ACM8F945 A0ACM8F945 LOC120850583 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120844232|UniProtKB=A0ACM8FIH3 A0ACM8FIH3 LOC120844232 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120838195|UniProtKB=A0ACM8EIS2 A0ACM8EIS2 LOC120838195 PTHR43078:SF54 UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED UDP-GLUCURONIC ACID DECARBOXYLASE 1 lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 lyase#PC00144;decarboxylase#PC00089 IXOSC|EnsemblGenome=LOC8051187|UniProtKB=A0ACM8E835 A0ACM8E835 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120839502|UniProtKB=A0ACM8ELB8 A0ACM8ELB8 LOC120839502 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115309338|UniProtKB=A0ACM8F751 A0ACM8F751 LOC115309338 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115333176|UniProtKB=A0ACM8F574 A0ACM8F574 LOC115333176 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120847461|UniProtKB=A0ACM8F481 A0ACM8F481 LOC120847461 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115313189|UniProtKB=A0ACM8FPC3 A0ACM8FPC3 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029797|UniProtKB=A0ACM8DR59 A0ACM8DR59 LOC8029797 PTHR23345:SF15 VITELLOGENIN-RELATED VITELLOGENIN-6 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 storage protein#PC00210 IXOSC|EnsemblGenome=LOC115308345|UniProtKB=A0ACM8DME5 A0ACM8DME5 LOC115308345 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120842158|UniProtKB=A0ACM8ET67 A0ACM8ET67 LOC120842158 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115332562|UniProtKB=A0ACM8EDV9 A0ACM8EDV9 LOC115332562 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840882|UniProtKB=A0ACM8FQ94 A0ACM8FQ94 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8038926|UniProtKB=A0ACM8FT90 A0ACM8FT90 LOC8038926 PTHR23023:SF317 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115320929|UniProtKB=A0ACM8ENM2 A0ACM8ENM2 LOC115320929 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034700|UniProtKB=A0ACM8DXU9 A0ACM8DXU9 LOC8034700 PTHR46462:SF3 UPSET, ISOFORM A UPSET, ISOFORM A regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;Rpd3L-Expanded complex#GO:0070210;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8034721|UniProtKB=A0ACM8DYD7 A0ACM8DYD7 LOC8034721 PTHR13213:SF3 MYB-BINDING PROTEIN 1A FAMILY MEMBER MYB-BINDING PROTEIN 1A transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115316555|UniProtKB=A0ACM8ERQ8 A0ACM8ERQ8 LOC115316555 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053579|UniProtKB=A0ACM8EGD2 A0ACM8EGD2 LOC8053579 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121836484|UniProtKB=A0ACM8FYU8 A0ACM8FYU8 LOC121836484 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040049|UniProtKB=A0ACM8E2L4 A0ACM8E2L4 vari PTHR23122:SF69 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK FI17352P1 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115325428|UniProtKB=A0ACM8E4W2 A0ACM8E4W2 LOC115325428 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115320445|UniProtKB=A0ACM8EXM5 A0ACM8EXM5 LOC115320445 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115320086|UniProtKB=A0ACM8ERR4 A0ACM8ERR4 LOC115320086 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8034773|UniProtKB=A0ACM8EYQ8 A0ACM8EYQ8 LOC8034773 PTHR45797:SF3 RAD54-LIKE ATP-DEPENDENT HELICASE ATRX catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;transcription regulator activity#GO:0140110 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115316226|UniProtKB=A0ACM8EVI8 A0ACM8EVI8 LOC115316226 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8038473|UniProtKB=A0ACM8F7V7 A0ACM8F7V7 LOC8038473 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8043646|UniProtKB=A0ACM8EBS2 A0ACM8EBS2 mst PTHR13391:SF1 MITOCHONDRIAL DISTRIBUTION REGULATOR MISATO PROTEIN MISATO HOMOLOG 1 mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8024570|UniProtKB=A0ACM8DIF8 A0ACM8DIF8 LOC8024570 PTHR15853:SF1 THIOREDOXIN-RELATED THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2 HOMOLOG catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 membrane#GO:0016020;cytoplasm#GO:0005737;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115312538|UniProtKB=A0ACM8DS46 A0ACM8DS46 LOC115312538 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to heat#GO:0009408;response to stress#GO:0006950;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein folding#GO:0006457;response to stimulus#GO:0050896;protein refolding#GO:0042026;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC115320225|UniProtKB=A0ACM8ETC5 A0ACM8ETC5 LOC115320225 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8034680|UniProtKB=A0ACM8EHL3 A0ACM8EHL3 LOC8034680 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8031989|UniProtKB=A0ACM8E0T2 A0ACM8E0T2 LOC8031989 PTHR11733:SF245 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-1 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115330709|UniProtKB=A0ACM8EB48 A0ACM8EB48 LOC115330709 PTHR11727:SF34 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102 macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;methylation#GO:0032259;macromolecule modification#GO:0043412;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA methylation#GO:0031167;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8035153|UniProtKB=A0ACM8DWM5 A0ACM8DWM5 LOC8035153 PTHR39299:SF1 TRANSMEMBRANE PROTEIN DUF7789 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837491|UniProtKB=A0ACM8G3P8 A0ACM8G3P8 LOC121837491 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8053762|UniProtKB=A0ACM8DLQ7 A0ACM8DLQ7 Pmi PTHR15099:SF2 PROTEIN PM1 TRANSMEMBRANE PROTEIN 11, MITOCHONDRIAL mitochondrion organization#GO:0007005;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;cellular component organization or biogenesis#GO:0071840 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=ISCI020627|UniProtKB=B7Q2M2 B7Q2M2 ISCW020627 PTHR31148:SF1 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 IXOSC|EnsemblGenome=LOC120849201|UniProtKB=A0ACM8F884 A0ACM8F884 LOC120849201 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120841473|UniProtKB=A0ACM8ERP2 A0ACM8ERP2 140up PTHR13002:SF1 C3ORF1 PROTEIN-RELATED COMPLEX I ASSEMBLY FACTOR TIMMDC1, MITOCHONDRIAL intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC121838073|UniProtKB=A0ACM8G6J3 A0ACM8G6J3 LOC121838073 PTHR14950:SF82 DICER-RELATED ENDORIBONUCLEASE DICER nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;RNA binding#GO:0003723;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;binding#GO:0005488;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;cell death#GO:0008219;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070;DNA catabolic process#GO:0006308;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;execution phase of apoptosis#GO:0097194;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;apoptotic DNA fragmentation#GO:0006309;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8023317|UniProtKB=A0ACM8DGQ5 A0ACM8DGQ5 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 IXOSC|EnsemblGenome=LOC120842717|UniProtKB=A0ACM8EUF1 A0ACM8EUF1 LOC120842717 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026958|UniProtKB=A0ACM8E4G0 A0ACM8E4G0 PTHR46170:SF1 GATOR COMPLEX PROTEIN WDR59 GATOR2 COMPLEX PROTEIN WDR59 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of TORC1 signaling#GO:1903432;cellular response to starvation#GO:0009267;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to amino acid starvation#GO:0034198;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to nutrient levels#GO:0031667;positive regulation of TORC1 signaling#GO:1904263;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;vacuolar membrane#GO:0005774;Seh1-associated complex#GO:0035859;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121835841|UniProtKB=A0ACM8FW00 A0ACM8FW00 LOC121835841 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313994|UniProtKB=A0ACM8F3I0 A0ACM8F3I0 LOC115313994 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED transferase#PC00220;nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC115311990|UniProtKB=A0ACM8DRF2 A0ACM8DRF2 LOC115311990 PTHR24252:SF7 ACROSIN-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-LIKE ISOFORM X1 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121834270|UniProtKB=A0ACM8FPE1 A0ACM8FPE1 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120838678|UniProtKB=A0ACM8EKE7 A0ACM8EKE7 LOC120838678 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8027767|UniProtKB=A0ACM8DJC6 A0ACM8DJC6 LOC8027767 PTHR21032:SF0 G PATCH DOMAIN-CONTAINING PROTEIN 11 G PATCH DOMAIN-CONTAINING PROTEIN 11 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856 IXOSC|EnsemblGenome=LOC8051822|UniProtKB=A0ACM8DLM3 A0ACM8DLM3 Kap3 PTHR15605:SF2 KINESIN-ASSOCIATED PROTEINS KINESIN-ASSOCIATED PROTEIN 3 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;plasma membrane bounded cell projection organization#GO:0120036 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;cilium#GO:0005929;intracellular organelle#GO:0043229;ciliary transition zone#GO:0035869;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8038600|UniProtKB=A0ACM8FX85 A0ACM8FX85 LOC8038600 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120850227|UniProtKB=A0ACM8FBI7 A0ACM8FBI7 LOC120850227 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836107|UniProtKB=A0ACM8FMM4 A0ACM8FMM4 LOC120836107 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED transferase#PC00220;nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC8030789|UniProtKB=A0ACM8F7U5 A0ACM8F7U5 LOC8030789 PTHR35970:SF1 SODIUM CHANNEL AND CLATHRIN LINKER 1 SODIUM CHANNEL AND CLATHRIN LINKER 1 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120849730|UniProtKB=A0ACM8F792 A0ACM8F792 LOC120849730 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115324244|UniProtKB=A0ACM8E4Z8 A0ACM8E4Z8 LOC115324244 PTHR48101:SF4 METHYLMALONYL-COA MUTASE, MITOCHONDRIAL-RELATED METHYLMALONYL-COA MUTASE, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;tetrapyrrole binding#GO:0046906;isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;nucleobase-containing compound metabolic process#GO:0006139;lipid catabolic process#GO:0016042;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;purine-containing compound catabolic process#GO:0072523;sulfur compound catabolic process#GO:0044273;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 mutase#PC00160;isomerase#PC00135;metabolite interconversion enzyme#PC00262 Methylmalonyl pathway#P02755>Methylmalonyl-CoA mutase#P03034;Succinate to proprionate conversion#P02777>Methylmalonyl-CoA mutase#P03161 IXOSC|EnsemblGenome=LOC115315904|UniProtKB=A0ACM8F8N0 A0ACM8F8N0 LOC120849745 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043384|UniProtKB=A0ACM8FJY0 A0ACM8FJY0 PTHR14695:SF9 SHC SH2-DOMAIN BINDING PROTEIN 1-RELATED PROTEIN NESSUN DORMA developmental process#GO:0032502;spermatogenesis#GO:0007283;meiotic cell cycle#GO:0051321;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;cellular process#GO:0009987;organelle organization#GO:0006996;male meiotic nuclear division#GO:0007140;male gamete generation#GO:0048232;sexual reproduction#GO:0019953;cytokinesis#GO:0000910;nuclear division#GO:0000280;multicellular organismal reproductive process#GO:0048609;cytoskeleton-dependent cytokinesis#GO:0061640;organelle fission#GO:0048285;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;developmental process involved in reproduction#GO:0003006;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;reproductive process#GO:0022414;gamete generation#GO:0007276 IXOSC|EnsemblGenome=LOC115310654|UniProtKB=A0ACM8EH09 A0ACM8EH09 LOC115310654 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120843290|UniProtKB=A0ACM8EVT1 A0ACM8EVT1 LOC120843290 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115311472|UniProtKB=A0ACM8EWS6 A0ACM8EWS6 LOC115311472 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313635|UniProtKB=A0ACM8F3T0 A0ACM8F3T0 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031766|UniProtKB=A0ACM8FQC0 A0ACM8FQC0 LOC8031766 PTHR46129:SF2 SYNAPTOTAGMIN 14, ISOFORM D SYNAPTOTAGMIN 14, ISOFORM D binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8023649|UniProtKB=A0ACM8DMM1 A0ACM8DMM1 Rab5 PTHR47978:SF52 FAMILY NOT NAMED SMALL MONOMERIC GTPASE catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8039353|UniProtKB=A0ACM8DT55 A0ACM8DT55 LOC8039353 PTHR12271:SF66 POLY A POLYMERASE CID PAP -RELATED GH05885P transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401 nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC8039020|UniProtKB=A0ACM8DV40 A0ACM8DV40 LOC8039020 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8035589|UniProtKB=A0ACM8FQ17 A0ACM8FQ17 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220 IXOSC|EnsemblGenome=LOC120850210|UniProtKB=A0ACM8F9C8 A0ACM8F9C8 LOC120850210 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120844571|UniProtKB=A0ACM8EYY2 A0ACM8EYY2 LOC120844571 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837447|UniProtKB=A0ACM8G6E2 A0ACM8G6E2 LOC120837447 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC121048374|UniProtKB=A0ACM8FI97 A0ACM8FI97 LOC121048374 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041343|UniProtKB=A0ACM8FV75 A0ACM8FV75 LOC8041343 PTHR14881:SF4 LISH DOMAIN-CONTAINING PROTEIN ARMC9 LISH DOMAIN-CONTAINING PROTEIN ARMC9 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cilium#GO:0005929;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8039312|UniProtKB=A0ACM8E315 A0ACM8E315 LOC8039312 PTHR19325:SF537 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING FURROWED, ISOFORM A defense/immunity protein#PC00090;complement component#PC00078 IXOSC|EnsemblGenome=LOC115313831|UniProtKB=A0ACM8DTI3 A0ACM8DTI3 LOC115313831 PTHR21146:SF3 MEF2B PROTEIN BLOC-1-RELATED COMPLEX SUBUNIT 8 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 p38 MAPK pathway#P05918>MEF#P06023 IXOSC|EnsemblGenome=LOC8036688|UniProtKB=A0ACM8ECX1 A0ACM8ECX1 LOC8036688 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8027077|UniProtKB=A0ACM8EHR2 A0ACM8EHR2 LOC8027077 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120846167|UniProtKB=A0ACM8F0Z7 A0ACM8F0Z7 LOC120846167 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121835195|UniProtKB=A0ACM8FRX3 A0ACM8FRX3 LOC121835195 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8053021|UniProtKB=A0ACM8DQY4 A0ACM8DQY4 unc-119 PTHR12951:SF1 RETINAL PROTEIN 4 PROTEIN UNC-119 HOMOLOG binding#GO:0005488;lipid binding#GO:0008289 cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;localization#GO:0051179;protein transport#GO:0015031;cilium organization#GO:0044782;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;establishment of protein localization#GO:0045184;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cilium#GO:0005929 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115308533|UniProtKB=A0ACM8EJJ3 A0ACM8EJJ3 LOC115308533 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8030819|UniProtKB=A0ACM8EKE6 A0ACM8EKE6 LOC8030819 PTHR24365:SF555 TOLL-LIKE RECEPTOR MSTPROX-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8036756|UniProtKB=A0ACM8FMZ9 A0ACM8FMZ9 PTHR10378:SF50 LIM DOMAIN-BINDING PROTEIN CHIP, ISOFORM B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC120847383|UniProtKB=A0ACM8F346 A0ACM8F346 LOC120847383 PTHR11373:SF4 DEOXYNUCLEOSIDE TRIPHOSPHATE TRIPHOSPHOHYDROLASE FALTEN, ISOFORM B phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide metabolic process#GO:0006163;purine nucleoside triphosphate metabolic process#GO:0009144;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;purine nucleotide catabolic process#GO:0006195 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121833985|UniProtKB=A0ACM8FPS9 A0ACM8FPS9 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386 nucleotide-excision repair#GO:0006289;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;response to stimulus#GO:0050896;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA repair#GO:0006281;DNA damage response#GO:0006974;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115330238|UniProtKB=A0ACM8FYU4 A0ACM8FYU4 LOC115330238 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8024369|UniProtKB=A0ACM8F7Q8 A0ACM8F7Q8 LOC8024369 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8053248|UniProtKB=A0ACM8FLC4 A0ACM8FLC4 LOC8053248 PTHR45656:SF4 PROTEIN CBR-CLEC-78 COMPLEMENT COMPONENT RECEPTOR 1-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8024632|UniProtKB=A0ACM8DIG5 A0ACM8DIG5 LOC8024632 PTHR31428:SF6 RGM DOMAIN FAMILY MEMBER DRAG-1 REPULSIVE GUIDANCE MOLECULE B HOMOLOG DRAG-1 coreceptor activity#GO:0015026;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8031217|UniProtKB=A0ACM8DI11 A0ACM8DI11 LOC8031217 PTHR10146:SF18 PROLINE SYNTHETASE CO-TRANSCRIBED BACTERIAL HOMOLOG PROTEIN PYRIDOXAL PHOSPHATE HOMEOSTASIS PROTEIN binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363 small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8038263|UniProtKB=A0ACM8EYH2 A0ACM8EYH2 LOC8038263 PTHR46460:SF1 METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115316496|UniProtKB=A0ACM8DWL7 A0ACM8DWL7 LOC115316496 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8052426|UniProtKB=A0ACM8DLM9 A0ACM8DLM9 LOC8052426 PTHR12651:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 9 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;proteasome complex#GO:0000502;cytosol#GO:0005829;peptidase complex#GO:1905368;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC8033792|UniProtKB=A0ACM8DR96 A0ACM8DR96 LOC8033792 PTHR24399:SF70 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121835999|UniProtKB=A0ACM8FWQ0 A0ACM8FWQ0 LOC121835999 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036156|UniProtKB=A0ACM8EHY3 A0ACM8EHY3 PTHR11085:SF24 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;deacylase activity#GO:0160215;transferase activity#GO:0016740;catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407 nucleus#GO:0005634;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8040109|UniProtKB=A0ACM8FGB8 A0ACM8FGB8 LOC8040109 PTHR23301:SF111 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8034452|UniProtKB=A0ACM8EZF9 A0ACM8EZF9 Tep2 PTHR11412:SF136 MACROGLOBULIN / COMPLEMENT CD109 ANTIGEN peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;immune system process#GO:0002376;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115322451|UniProtKB=A0ACM8E2R6 A0ACM8E2R6 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120839537|UniProtKB=A0ACM8EM79 A0ACM8EM79 LOC120839537 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8051061|UniProtKB=A0ACM8DNT2 A0ACM8DNT2 LOC8051061 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120841689|UniProtKB=A0ACM8ESA8 A0ACM8ESA8 LOC120841689 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121833429|UniProtKB=A0ACM8FLY0 A0ACM8FLY0 LOC121833429 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8052842|UniProtKB=A0ACM8DLJ0 A0ACM8DLJ0 LOC8052842 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8051710|UniProtKB=A0ACM8DX78 A0ACM8DX78 LOC8051710 PTHR10127:SF793 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8025994|UniProtKB=A0ACM8E3R2 A0ACM8E3R2 LOC8025994 PTHR12366:SF29 ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE ASPARTYL BETA-HYDROXYLASE, ISOFORM L catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8044009|UniProtKB=A0ACM8ED91 A0ACM8ED91 LOC8044009 PTHR10063:SF11 TUBERIN RHO GTPASE-ACTIVATING PROTEIN CG5521-RELATED enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC8042293|UniProtKB=A0ACM8EKQ9 A0ACM8EKQ9 LOC8042293 PTHR11588:SF540 TUBULIN TUBULIN GAMMA CHAIN carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;microtubule polymerization or depolymerization#GO:0031109;mitotic sister chromatid segregation#GO:0000070;mitotic cell cycle process#GO:1903047;microtubule polymerization#GO:0046785;chromosome organization#GO:0051276;spindle organization#GO:0007051;mitotic spindle organization#GO:0007052;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;nuclear division#GO:0000280;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321 supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;microtubule#GO:0005874;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;tubulin#PC00228 IXOSC|EnsemblGenome=LOC120841109|UniProtKB=A0ACM8ERY2 A0ACM8ERY2 LOC120841109 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317770|UniProtKB=A0ACM8F0Z6 A0ACM8F0Z6 LOC115317770 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835349|UniProtKB=A0ACM8FSS7 A0ACM8FSS7 LOC121835349 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8025384|UniProtKB=A0ACM8EBE3 A0ACM8EBE3 LOC8025384 PTHR45709:SF3 LARGE SUBUNIT GTPASE 1 HOMOLOG-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 1 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 IXOSC|EnsemblGenome=LOC8052109|UniProtKB=A0ACM8DTU7 A0ACM8DTU7 LOC8052109 PTHR23147:SF189 SERINE/ARGININE RICH SPLICING FACTOR SERINE AND ARGININE-RICH-SPLICING FACTOR 3A-RELATED organelle lumen#GO:0043233;nuclear speck#GO:0016607;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8032619|UniProtKB=A0ACM8DV61 A0ACM8DV61 LOC8032619 PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075 cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC115332918|UniProtKB=A0ACM8EHE3 A0ACM8EHE3 LOC115332918 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120843721|UniProtKB=A0ACM8EWI9 A0ACM8EWI9 LOC120843721 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8027409|UniProtKB=A0ACM8E1S6 A0ACM8E1S6 LOC8027409 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC120842113|UniProtKB=A0ACM8FF75 A0ACM8FF75 LOC120842113 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315573|UniProtKB=A0ACM8DVF5 A0ACM8DVF5 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell adhesion#GO:0007155;post-embryonic development#GO:0009791 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8033907|UniProtKB=A0ACM8DIJ4 A0ACM8DIJ4 Su(H) PTHR10665:SF0 RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS SUPPRESSOR OF HAIRLESS PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 Angiogenesis#P00005>CSL#P00233;Alzheimer disease-presenilin pathway#P00004>CSL#P00158;Notch signaling pathway#P00045>Su(H)#P01101 IXOSC|EnsemblGenome=LOC8031185|UniProtKB=A0ACM8ETZ6 A0ACM8ETZ6 Elp3 PTHR11135:SF0 HISTONE ACETYLTRANSFERASE-RELATED ELONGATOR COMPLEX PROTEIN 3 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;elongator holoenzyme complex#GO:0033588;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8052498|UniProtKB=A0ACM8DLJ9 A0ACM8DLJ9 LOC8052498 PTHR16121:SF2 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 2 O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC121832958|UniProtKB=A0ACM8FT18 A0ACM8FT18 LOC121832958 PTHR24381:SF470 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8023913|UniProtKB=A0ACM8G495 A0ACM8G495 LOC8023913 PTHR21580:SF28 SHIPPO-1-RELATED SPERM-TAIL PG-RICH REPEAT FAMILY PROTEIN cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232 structural protein#PC00211 IXOSC|EnsemblGenome=LOC120847851|UniProtKB=A0ACM8F4T7 A0ACM8F4T7 LOC120847851 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121834195|UniProtKB=A0ACM8FN35 A0ACM8FN35 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;reproductive process#GO:0022414;homologous recombination#GO:0035825;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8050540|UniProtKB=A0ACM8EEG3 A0ACM8EEG3 mRpS31 PTHR13231:SF3 MITOCHONDRIAL RIBOSOMAL PROTEIN S31 SMALL RIBOSOMAL SUBUNIT PROTEIN MS31 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8035518|UniProtKB=A0ACM8FB77 A0ACM8FB77 LOC8035518 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121835373|UniProtKB=A0ACM8FSZ1 A0ACM8FSZ1 LOC121835373 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein metabolic process#GO:0019538;protein refolding#GO:0042026;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;protein folding#GO:0006457 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC8024779|UniProtKB=A0ACM8G4D4 A0ACM8G4D4 LOC8024779 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8026460|UniProtKB=A0ACM8DVD8 A0ACM8DVD8 LOC8026460 PTHR24102:SF28 PHD FINGER PROTEIN PHD-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835869|UniProtKB=A0ACM8FXA9 A0ACM8FXA9 LOC121835869 PTHR46600:SF13 THAP DOMAIN-CONTAINING SI:DKEY-228B2.6 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8027556|UniProtKB=A0ACM8DWI1 A0ACM8DWI1 PTHR14625:SF3 MICROCEPHALIN MICROCEPHALIN mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle#GO:0007049 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8037259|UniProtKB=A0ACM8EEY1 A0ACM8EEY1 LOC8037259 PTHR22726:SF1 METALLOENDOPEPTIDASE OMA1 METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8032138|UniProtKB=A0ACM8DTZ0 A0ACM8DTZ0 LOC8032138 PTHR24170:SF1 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 27 DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G09870)-RELATED guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;late endosome#GO:0005770;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115310708|UniProtKB=A0ACM8EMS8 A0ACM8EMS8 LOC115310708 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844570|UniProtKB=A0ACM8EYP2 A0ACM8EYP2 LOC120844570 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332191|UniProtKB=A0ACM8ED79 A0ACM8ED79 LOC115332191 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8028489|UniProtKB=A0ACM8E120 A0ACM8E120 LOC8028489 PTHR11360:SF325 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN monocarboxylic acid transmembrane transporter activity#GO:0008028;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8051722|UniProtKB=A0ACM8E521 A0ACM8E521 LOC8051722 PTHR23419:SF8 DIVALENT CATION TOLERANCE CUTA-RELATED FI09726P ion binding#GO:0043167;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115328593|UniProtKB=A0ACM8EYN8 A0ACM8EYN8 LOC115328593 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115315832|UniProtKB=A0ACM8G2W5 A0ACM8G2W5 LOC115315832 PTHR10751:SF144 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 G-protein#PC00020;heterotrimeric G-protein#PC00117 IXOSC|EnsemblGenome=LOC8039023|UniProtKB=A0ACM8EZ78 A0ACM8EZ78 LOC8039023 PTHR14024:SF49 PERILIPIN LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 1 regulation of localization#GO:0032879;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;lipid storage#GO:0019915;positive regulation of biological process#GO:0048518 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120849657|UniProtKB=A0ACM8F935 A0ACM8F935 LOC120849657 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC8040114|UniProtKB=A0ACM8DVF2 A0ACM8DVF2 LOC8040114 PTHR20992:SF9 AT15442P-RELATED AT15442P-RELATED IXOSC|EnsemblGenome=LOC121832965|UniProtKB=A0ACM8FKE2 A0ACM8FKE2 LOC121832965 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 microbody#GO:0042579;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121837728|UniProtKB=A0ACM8G5Y0 A0ACM8G5Y0 LOC121837728 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026671|UniProtKB=A0ACM8FWY8 A0ACM8FWY8 LOC8026671 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=ISCI003920|UniProtKB=B7PJS6 B7PJS6 ISCW003920 PTHR43512:SF7 TRANSLATION FACTOR GUF1-RELATED TRANSLATION FACTOR GUF1, MITOCHONDRIAL binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of translation#GO:0045727;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8052667|UniProtKB=A0ACM8E2Z5 A0ACM8E2Z5 LOC8052667 PTHR46306:SF1 BTB/POZ DOMAIN-CONTAINING PROTEIN 9 BTB_POZ DOMAIN-CONTAINING PROTEIN 9 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of signaling#GO:0023051;rhythmic process#GO:0048511;circadian rhythm#GO:0007623 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115325743|UniProtKB=A0ACM8ESM1 A0ACM8ESM1 LOC115325743 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;steroid metabolic process#GO:0008202;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8034532|UniProtKB=A0ACM8DJG0 A0ACM8DJG0 PTHR15201:SF1 CRSP70 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC120846968|UniProtKB=A0ACM8FVB8 A0ACM8FVB8 LOC120846968 PTHR46017:SF1 ALPHA-MANNOSIDASE 2C1 ALPHA-MANNOSIDASE 2C1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;oligosaccharide catabolic process#GO:0009313;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311 IXOSC|EnsemblGenome=LOC115308324|UniProtKB=A0ACM8EMT8 A0ACM8EMT8 LOC115308324 PTHR10342:SF274 ARYLSULFATASE SULFATASE N-TERMINAL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046936|UniProtKB=A0ACM8FDW8 A0ACM8FDW8 LOC121046936 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8023672|UniProtKB=A0ACM8EJJ0 A0ACM8EJJ0 LOC8023672 PTHR11472:SF1 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPD helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8042463|UniProtKB=A0ACM8EE83 A0ACM8EE83 LOC8042463 PTHR12992:SF11 NUDIX HYDROLASE MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound catabolic process#GO:0044273;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8024866|UniProtKB=A0ACM8DIP7 A0ACM8DIP7 ND-13A PTHR13156:SF0 NADH-UBIQUINONE OXIDOREDUCTASE 13 KD-A SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 6, MITOCHONDRIAL electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;organelle membrane#GO:0031090;transporter complex#GO:1990351;respiratory chain complex I#GO:0045271;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053011|UniProtKB=A0ACM8DQX5 A0ACM8DQX5 LOC8053011 PTHR11558:SF11 SPERMIDINE/SPERMINE SYNTHASE SPERMIDINE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;polyamine biosynthetic process#GO:0006596;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 transferase#PC00220 IXOSC|EnsemblGenome=LOC120844553|UniProtKB=A0ACM8G0C2 A0ACM8G0C2 LOC120844553 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121834997|UniProtKB=A0ACM8FST9 A0ACM8FST9 LOC121834997 PTHR31912:SF38 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035163|UniProtKB=A0ACM8E0M7 A0ACM8E0M7 LOC8035163 PTHR43757:SF18 AMINOMETHYLTRANSFERASE PYRUVATE DEHYDROGENASE PHOSPHATASE REGULATORY SUBUNIT, MITOCHONDRIAL-LIKE transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8053047|UniProtKB=A0ACM8DLJ3 A0ACM8DLJ3 LOC8053047 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;metabolic process#GO:0008152;hexose metabolic process#GO:0019318;monosaccharide metabolic process#GO:0005996;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 kinase#PC00137;metabolite interconversion enzyme#PC00262;carbohydrate kinase#PC00065;transferase#PC00220 Fructose galactose metabolism#P02744>Galactokinase#P02960 IXOSC|EnsemblGenome=LOC8033564|UniProtKB=A0ACM8ELN5 A0ACM8ELN5 Nuak1 PTHR24343:SF304 SERINE/THREONINE KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115313162|UniProtKB=A0ACM8F0D5 A0ACM8F0D5 LOC115313162 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC121834551|UniProtKB=A0ACM8FP11 A0ACM8FP11 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8023986|UniProtKB=A0ACM8EVI0 A0ACM8EVI0 LOC8023986 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120839344|UniProtKB=A0ACM8ELN0 A0ACM8ELN0 LOC120839344 PTHR47163:SF5 DDE_TNP_IS1595 DOMAIN-CONTAINING PROTEIN ISXO2-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309814|UniProtKB=A0ACM8FB56 A0ACM8FB56 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120837069|UniProtKB=A0ACM8EH64 A0ACM8EH64 LOC120837069 PTHR21461:SF40 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN BETA-1,4-GALACTOSYLTRANSFERASE GALT-1 glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8053059|UniProtKB=A0ACM8DLJ7 A0ACM8DLJ7 LOC8053059 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120842934|UniProtKB=A0ACM8EUU6 A0ACM8EUU6 LOC120842934 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840460|UniProtKB=A0ACM8EP46 A0ACM8EP46 LOC120840460 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC115323462|UniProtKB=A0ACM8EJJ2 A0ACM8EJJ2 LOC115323462 PTHR48051:SF1 FAMILY NOT NAMED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8028863|UniProtKB=A0ACM8DHB4 A0ACM8DHB4 Mdh2 PTHR11540:SF76 MALATE AND LACTATE DEHYDROGENASE MALATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120841400|UniProtKB=A0ACM8FIX1 A0ACM8FIX1 LOC120841400 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8051188|UniProtKB=A0ACM8G4Q6 A0ACM8G4Q6 LOC8051188 PTHR10291:SF51 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;isoprenoid metabolic process#GO:0006720;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8038900|UniProtKB=A0ACM8EEF6 A0ACM8EEF6 LOC8038900 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120847424|UniProtKB=A0ACM8F461 A0ACM8F461 LOC120847424 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115324773|UniProtKB=A0ACM8FNH8 A0ACM8FNH8 LOC121833880 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839602|UniProtKB=A0ACM8EMR0 A0ACM8EMR0 LOC120839602 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220 IXOSC|EnsemblGenome=LOC120838726|UniProtKB=A0ACM8EJS2 A0ACM8EJS2 LOC120838726 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309225|UniProtKB=A0ACM8ET64 A0ACM8ET64 LOC115309225 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115319638|UniProtKB=A0ACM8EZR3 A0ACM8EZR3 LOC115319638 PTHR12585:SF27 SCC1 / RAD21 FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN REC8 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488 sister chromatid cohesion#GO:0007062;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;response to stress#GO:0006950 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115315613|UniProtKB=A0ACM8EJ44 A0ACM8EJ44 LOC115315613 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053486|UniProtKB=A0ACM8E3D0 A0ACM8E3D0 Mi-2 PTHR45623:SF9 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD3 nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;hydrolase activity#GO:0016787;DNA binding#GO:0003677;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8025064|UniProtKB=A0ACM8DTW5 A0ACM8DTW5 LOC8025064 PTHR43718:SF2 LON PROTEASE LON PROTEASE HOMOLOG, MITOCHONDRIAL catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;DNA binding#GO:0003677 mitochondrion organization#GO:0007005;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115310215|UniProtKB=A0ACM8EK12 A0ACM8EK12 LOC115310215 PTHR19290:SF134 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC120840602|UniProtKB=A0ACM8EQH7 A0ACM8EQH7 LOC120840602 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115332430|UniProtKB=A0ACM8G617 A0ACM8G617 LOC115332430 PTHR10791:SF112 RAG1-ACTIVATING PROTEIN 1 SUGAR TRANSPORTER SWEET1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;carbohydrate transport#GO:0008643 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120847776|UniProtKB=A0ACM8F4H8 A0ACM8F4H8 LOC120847776 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039877|UniProtKB=A0ACM8EDW8 A0ACM8EDW8 LOC8039877 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8037936|UniProtKB=A0ACM8FC96 A0ACM8FC96 LOC8037936 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120850361|UniProtKB=A0ACM8FA08 A0ACM8FA08 LOC120850361 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838429|UniProtKB=A0ACM8FEJ3 A0ACM8FEJ3 LOC120840697 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042418|UniProtKB=A0ACM8DUR3 A0ACM8DUR3 LOC8042418 PTHR13164:SF3 CALICYLIN BINDING PROTEIN CALCYCLIN-BINDING PROTEIN ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 circulatory system development#GO:0072359;heart development#GO:0007507;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115316766|UniProtKB=A0ACM8DWA9 A0ACM8DWA9 LOC115316766 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8028684|UniProtKB=A0ACM8E4L0 A0ACM8E4L0 LOC8028684 PTHR32003:SF1 PROTEIN FAM199X PROTEIN FAM199X IXOSC|EnsemblGenome=LOC8042290|UniProtKB=A0ACM8E7B9 A0ACM8E7B9 LOC8042290 PTHR43066:SF21 RHOMBOID-RELATED PROTEIN RHOMBOID-LIKE PROTEIN 18-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8034814|UniProtKB=A0ACM8FKS7 A0ACM8FKS7 LOC8034814 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120846035|UniProtKB=A0ACM8F1C2 A0ACM8F1C2 LOC120846035 PTHR11533:SF299 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8036742|UniProtKB=A0ACM8DZG2 A0ACM8DZG2 LOC8036742 PTHR45704:SF18 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE IXOSC|EnsemblGenome=LOC120846702|UniProtKB=A0ACM8F316 A0ACM8F316 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030446|UniProtKB=A0ACM8DH46 A0ACM8DH46 CHMP2B PTHR10476:SF40 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 2B membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120846999|UniProtKB=A0ACM8F3P0 A0ACM8F3P0 LOC120846999 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8028448|UniProtKB=A0ACM8G1R6 A0ACM8G1R6 LOC8028448 PTHR37456:SF15 SI:CH211-266K2.1 MULTIPLEXIN IXOSC|EnsemblGenome=LOC8042984|UniProtKB=A0ACM8EDS5 A0ACM8EDS5 LOC8042984 PTHR21016:SF4 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of Notch signaling pathway#GO:0045747;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC8028379|UniProtKB=A0ACM8DJN0 A0ACM8DJN0 LOC8028379 PTHR10361:SF70 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120842230|UniProtKB=A0ACM8G1D6 A0ACM8G1D6 LOC120842230 PTHR19290:SF134 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIC DIFFERENTIATION FACTOR 1 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;sensory organ development#GO:0007423;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8041750|UniProtKB=A0ACM8EY07 A0ACM8EY07 LOC8041750 PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC115332002|UniProtKB=A0ACM8FQ07 A0ACM8FQ07 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8026374|UniProtKB=A0ACM8FZ21 A0ACM8FZ21 LOC8026374 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC121046778|UniProtKB=A0ACM8FEP6 A0ACM8FEP6 LOC121046778 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309123|UniProtKB=A0ACM8EMS0 A0ACM8EMS0 LOC115309123 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043235|UniProtKB=A0ACM8DS59 A0ACM8DS59 LOC8043235 PTHR12929:SF10 SOLUTE CARRIER FAMILY 52 RIBOFLAVIN TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;vitamin transport#GO:0051180;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120837293|UniProtKB=A0ACM8EGY5 A0ACM8EGY5 LOC121837610 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837386|UniProtKB=A0ACM8FLJ1 A0ACM8FLJ1 LOC120837386 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844448|UniProtKB=A0ACM8EYT9 A0ACM8EYT9 LOC120844448 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120851152|UniProtKB=A0ACM8FQB8 A0ACM8FQB8 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115327490|UniProtKB=A0ACM8E759 A0ACM8E759 LOC115327490 PTHR24417:SF7 SERINE/THREONINE-PROTEIN KINASE LMTK1 CHROMATIN MODIFICATION-RELATED PROTEIN EAF1 protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8028710|UniProtKB=A0ACM8DH41 A0ACM8DH41 LOC8028710 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200 IXOSC|EnsemblGenome=LOC8033775|UniProtKB=A0ACM8G2G8 A0ACM8G2G8 LOC8033775 PTHR22906:SF43 PROPERDIN PROPERDIN IXOSC|EnsemblGenome=LOC121047307|UniProtKB=A0ACM8FFS6 A0ACM8FFS6 LOC121047307 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051359|UniProtKB=A0ACM8E8Z3 A0ACM8E8Z3 LOC8051359 PTHR19229:SF284 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ABC TRANSPORTER DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8038814|UniProtKB=A0ACM8FEG8 A0ACM8FEG8 DppIII PTHR23422:SF11 DIPEPTIDYL PEPTIDASE III-RELATED DIPEPTIDYL PEPTIDASE 3 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8025045|UniProtKB=A0ACM8DIY6 A0ACM8DIY6 LOC8025045 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120838157|UniProtKB=A0ACM8EIN3 A0ACM8EIN3 LOC120838157 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029992|UniProtKB=A0ACM8DUN6 A0ACM8DUN6 LOC8029992 PTHR13976:SF76 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED AT27789P ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121838383|UniProtKB=A0ACM8G7W2 A0ACM8G7W2 LOC121838383 PTHR48069:SF3 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;tetrahydrofolate biosynthetic process#GO:0046654 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 reductase#PC00198;oxidoreductase#PC00176 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948 IXOSC|EnsemblGenome=LOC120844653|UniProtKB=A0ACM8EZB4 A0ACM8EZB4 LOC120844653 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115320370|UniProtKB=A0ACM8G8D3 A0ACM8G8D3 LOC115320370 PTHR45931:SF20 SI:CH211-59O9.10 RING-TYPE DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115332061|UniProtKB=A0ACM8EE37 A0ACM8EE37 LOC115332061 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037361|UniProtKB=A0ACM8E7Q2 A0ACM8E7Q2 LOC8037361 PTHR15922:SF2 NEUROBLASTOMA-AMPLIFIED SEQUENCE NBAS SUBUNIT OF NRZ TETHERING COMPLEX SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115308216|UniProtKB=A0ACM8FWR4 A0ACM8FWR4 LOC115308216 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120844087|UniProtKB=A0ACM8EXT2 A0ACM8EXT2 LOC120844087 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115329587|UniProtKB=A0ACM8G2R2 A0ACM8G2R2 LOC115329587 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843859|UniProtKB=A0ACM8EX02 A0ACM8EX02 LOC120843859 PTHR15924:SF9 CLE TRNA-SPLICING LIGASE COMPLEX SUBUNIT RTRAF nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC8025188|UniProtKB=A0ACM8EFH3 A0ACM8EFH3 LOC8025188 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115314340|UniProtKB=A0ACM8EGV6 A0ACM8EGV6 LOC115314340 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028086|UniProtKB=A0ACM8EE97 A0ACM8EE97 LOC8028086 PTHR11130:SF0 GLUTATHIONE SYNTHETASE GLUTATHIONE SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;cellular process#GO:0009987;biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142 IXOSC|EnsemblGenome=LOC8041444|UniProtKB=A0ACM8F9F5 A0ACM8F9F5 LOC8041444 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120838457|UniProtKB=A0ACM8EJV1 A0ACM8EJV1 PTHR46880:SF5 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849052|UniProtKB=A0ACM8F791 A0ACM8F791 PTHR13247:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11 MITOCHONDRIAL FISSION 1 PROTEIN binding#GO:0005488;lipid binding#GO:0008289 peroxisome organization#GO:0007031;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;peroxisome#GO:0005777;mitochondrion#GO:0005739;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle outer membrane#GO:0031968;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;membrane#GO:0016020;microbody#GO:0042579;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740 IXOSC|EnsemblGenome=LOC8025390|UniProtKB=A0ACM8EBD5 A0ACM8EBD5 LOC8025390 PTHR21082:SF4 PROTEIN INTURNED PROTEIN INTURNED multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;anatomical structure development#GO:0048856;cilium organization#GO:0044782;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120841265|UniProtKB=A0ACM8ESB4 A0ACM8ESB4 LOC120841265 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115327020|UniProtKB=A0ACM8E7E6 A0ACM8E7E6 LOC115327020 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8053853|UniProtKB=A0ACM8FAC9 A0ACM8FAC9 PTHR45999:SF4 UNC-13-4A, ISOFORM B UNC-13-4A, ISOFORM B IXOSC|EnsemblGenome=LOC8026030|UniProtKB=A0ACM8DWI2 A0ACM8DWI2 LOC8026030 PTHR11588:SF239 TUBULIN TUBULIN ALPHA CHAIN ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553 microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 tubulin#PC00228;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120839803|UniProtKB=A0ACM8EMK1 A0ACM8EMK1 LOC120839803 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115332137|UniProtKB=A0ACM8FTH0 A0ACM8FTH0 LOC115332137 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 IXOSC|EnsemblGenome=LOC115310965|UniProtKB=A0ACM8F4S8 A0ACM8F4S8 LOC115310965 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041161|UniProtKB=A0ACM8F6M0 A0ACM8F6M0 LOC8041161 PTHR47961:SF13 DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115327896|UniProtKB=A0ACM8E8F3 A0ACM8E8F3 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043871|UniProtKB=A0ACM8FUK7 A0ACM8FUK7 LOC8043871 PTHR24248:SF125 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE D2-LIKE RECEPTOR neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8034893|UniProtKB=A0ACM8ERI2 A0ACM8ERI2 LOC8034893 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED nucleotidyltransferase#PC00174;transferase#PC00220 IXOSC|EnsemblGenome=LOC8023718|UniProtKB=A0ACM8E0C7 A0ACM8E0C7 LOC8023718 PTHR22255:SF1 LP06548P LD32918P IXOSC|EnsemblGenome=LOC8038566|UniProtKB=A0ACM8FYF2 A0ACM8FYF2 LOC8038566 PTHR23167:SF69 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED FI18193P1 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin filament#GO:0005884;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120836292|UniProtKB=A0ACM8EHS7 A0ACM8EHS7 LOC120836292 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121836020|UniProtKB=A0ACM8FXN4 A0ACM8FXN4 LOC121836020 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8043330|UniProtKB=A0ACM8DL21 A0ACM8DL21 LOC8043330 PTHR14969:SF13 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE AT30094P phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8041524|UniProtKB=A0ACM8DSJ3 A0ACM8DSJ3 LOC8041524 PTHR24329:SF585 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC115329989|UniProtKB=A0ACM8EL53 A0ACM8EL53 LOC115329989 PTHR42687:SF1 L-THREONINE 3-DEHYDROGENASE L-THREONINE 3-DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121837821|UniProtKB=A0ACM8G6L3 A0ACM8G6L3 LOC121837821 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120837998|UniProtKB=A0ACM8EJT6 A0ACM8EJT6 LOC120837998 PTHR24031:SF292 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX54 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8028095|UniProtKB=A0ACM8EE63 A0ACM8EE63 LOC8028095 PTHR46853:SF1 METHYLOSOME PROTEIN 50 METHYLOSOME PROTEIN WDR77 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC121045557|UniProtKB=A0ACM8FBR3 A0ACM8FBR3 LOC121045557 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8053325|UniProtKB=A0ACM8E4S4 A0ACM8E4S4 GatB PTHR11659:SF5 GLUTAMYL-TRNA GLN AMIDOTRANSFERASE SUBUNIT B MITOCHONDRIAL AND PROKARYOTIC PET112-RELATED GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT B, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a tRNA#GO:0140101 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120837616|UniProtKB=A0ACM8EHX6 A0ACM8EHX6 LOC120837616 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8023646|UniProtKB=A0ACM8FJT0 A0ACM8FJT0 LOC8023646 PTHR23110:SF118 BTB DOMAIN TRANSCRIPTION FACTOR PROTEIN TRAMTRACK, ALPHA ISOFORM regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8039306|UniProtKB=A0ACM8FCF1 A0ACM8FCF1 Vps36 PTHR13128:SF12 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 36 establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;cellular localization#GO:0051641;protein transport#GO:0015031;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endosomal transport#GO:0016197;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;localization#GO:0051179;protein metabolic process#GO:0019538;protein localization to vacuole#GO:0072665;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;late endosome membrane#GO:0031902;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8034204|UniProtKB=A0ACM8EAE9 A0ACM8EAE9 LOC8034204 PTHR21290:SF69 SPHINGOMYELIN SYNTHETASE SPHINGOMYELIN SYNTHASE-RELATED PROTEIN 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;catalytic activity#GO:0003824;transferase activity#GO:0016740 ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide metabolic process#GO:0006672;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 IXOSC|EnsemblGenome=LOC8035129|UniProtKB=A0ACM8DV48 A0ACM8DV48 mRpS35 PTHR13490:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN MS35 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8036004|UniProtKB=A0ACM8FRP1 A0ACM8FRP1 LOC8036004 PTHR10480:SF12 PROTEIN UNC-13 HOMOLOG UNC-13, ISOFORM E syntaxin binding#GO:0019905;protein binding#GO:0005515;calmodulin binding#GO:0005516;SNARE binding#GO:0000149;binding#GO:0005488 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115330735|UniProtKB=A0ACM8EB90 A0ACM8EB90 LOC115330735 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036498|UniProtKB=A0ACM8FQB0 A0ACM8FQB0 LOC8036498 PTHR48012:SF41 STERILE20-LIKE KINASE, ISOFORM B-RELATED SERINE_THREONINE-PROTEIN KINASE PAKE-RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8032608|UniProtKB=A0ACM8DQW4 A0ACM8DQW4 Rnp4F PTHR17204:SF25 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED RRM DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;snRNA binding#GO:0017069;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115309272|UniProtKB=A0ACM8FA88 A0ACM8FA88 LOC115309272 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8053613|UniProtKB=A0ACM8FZK3 A0ACM8FZK3 Uba1 PTHR10953:SF4 UBIQUITIN-ACTIVATING ENZYME E1 E1 UBIQUITIN-ACTIVATING ENZYME catalytic activity, acting on a protein#GO:0140096;ligase activity#GO:0016874;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;response to stimulus#GO:0050896;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein modification process#GO:0036211 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 IXOSC|EnsemblGenome=LOC8025348|UniProtKB=A0ACM8E9X5 A0ACM8E9X5 LOC8025348 PTHR44329:SF146 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED SERINE_THREONINE-PROTEIN KINASE DDB_G0271682-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Raf#P00893 IXOSC|EnsemblGenome=LOC8025959|UniProtKB=A0ACM8FVV4 A0ACM8FVV4 LOC8025959 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395 metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115333180|UniProtKB=A0ACM8EEM3 A0ACM8EEM3 LOC115333180 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8025010|UniProtKB=A0ACM8DIX5 A0ACM8DIX5 LOC8025010 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115319083|UniProtKB=A0ACM8ES32 A0ACM8ES32 LOC115319083 PTHR19443:SF16 HEXOKINASE HEXOKINASE-2-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;hexokinase activity#GO:0004396;catalytic activity#GO:0003824;transferase activity#GO:0016740;carbohydrate kinase activity#GO:0019200;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Hexokinase#P00677;Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966 IXOSC|EnsemblGenome=LOC120836881|UniProtKB=A0ACM8EGN6 A0ACM8EGN6 LOC120836881 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121832870|UniProtKB=A0ACM8EQS2 A0ACM8EQS2 LOC121832870 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046203|UniProtKB=A0ACM8FDL9 A0ACM8FDL9 LOC121046203 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115318772|UniProtKB=A0ACM8DZ60 A0ACM8DZ60 LOC115318772 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121837785|UniProtKB=A0ACM8G659 A0ACM8G659 LOC121837785 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115309613|UniProtKB=A0ACM8DP11 A0ACM8DP11 LOC115309613 PTHR48438:SF2 ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED FUCOSYLTRANSFERASE IXOSC|EnsemblGenome=LOC115332512|UniProtKB=A0ACM8FFB6 A0ACM8FFB6 LOC115332512 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120841055|UniProtKB=A0ACM8ERU5 A0ACM8ERU5 LOC120841055 PTHR33559:SF1 PROTEASOME ASSEMBLY CHAPERONE 4 PROTEASOME ASSEMBLY CHAPERONE 4 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115329582|UniProtKB=A0ACM8F5W1 A0ACM8F5W1 LOC115329582 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8050760|UniProtKB=A0ACM8FI21 A0ACM8FI21 LOC8050760 PTHR19290:SF160 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED CLASS A BASIC HELIX-LOOP-HELIX PROTEIN 15 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC115324372|UniProtKB=A0ACM8E4K0 A0ACM8E4K0 LOC115325130 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324952|UniProtKB=A0ACM8E4H7 A0ACM8E4H7 LOC115324952 PTHR23310:SF62 ACYL-COA-BINDING PROTEIN, ACBP ACYL-COA-BINDING PROTEIN heterocyclic compound binding#GO:1901363;lipid binding#GO:0008289;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8052196|UniProtKB=A0ACM8DYM7 A0ACM8DYM7 LOC8052196 PTHR43806:SF14 PEPTIDASE S8 TRIPEPTIDYL-PEPTIDASE 2 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine hydrolase activity#GO:0017171 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 serine protease#PC00203 IXOSC|EnsemblGenome=LOC121835385|UniProtKB=A0ACM8FT12 A0ACM8FT12 LOC121835385 PTHR14633:SF3 LITTLE ELONGATION COMPLEX SUBUNIT 2 LITTLE ELONGATION COMPLEX SUBUNIT 2 regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;snRNA transcription by RNA polymerase III#GO:0042796;regulation of DNA-templated transcription#GO:0006355;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;transcription by RNA polymerase II#GO:0006366;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;transcription by RNA polymerase III#GO:0006383;snRNA transcription#GO:0009301;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467 IXOSC|EnsemblGenome=LOC120837960|UniProtKB=A0ACM8EJN3 A0ACM8EJN3 LOC120837960 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8027110|UniProtKB=A0ACM8EAZ7 A0ACM8EAZ7 LOC8027110 PTHR12591:SF0 GLUCOSE-6-PHOSPHATASE FI19814P1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC120850664|UniProtKB=A0ACM8FAF7 A0ACM8FAF7 LOC120850664 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053417|UniProtKB=A0ACM8E3F4 A0ACM8E3F4 Oscillin PTHR11280:SF5 GLUCOSAMINE-6-PHOSPHATE ISOMERASE GLUCOSAMINE-6-PHOSPHATE DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;protein binding#GO:0005515;identical protein binding#GO:0042802;deaminase activity#GO:0019239;catalytic activity#GO:0003824;binding#GO:0005488 carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino sugar catabolic process#GO:0046348 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 isomerase#PC00135 N-acetylglucosamine metabolism#P02756>Glucosamine-6-phosphate deaminase#P03041 IXOSC|EnsemblGenome=LOC8032966|UniProtKB=A0ACM8DH98 A0ACM8DH98 RpL40 PTHR10666:SF498 UBIQUITIN UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8032579|UniProtKB=A0ACM8FUC8 A0ACM8FUC8 LOC8032579 PTHR21650:SF4 MEMBRALIN/KINETOCHORE PROTEIN NUF2 MEMBRALIN regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;regulation of response to endoplasmic reticulum stress#GO:1905897;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of ERAD pathway#GO:1904292 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC115315189|UniProtKB=A0ACM8FPS3 A0ACM8FPS3 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8040624|UniProtKB=A0ACM8DQQ3 A0ACM8DQQ3 LOC8040624 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8052664|UniProtKB=A0ACM8FXS5 A0ACM8FXS5 LOC8052664 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8028826|UniProtKB=A0ACM8ELB4 A0ACM8ELB4 LOC8028826 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC115328108|UniProtKB=A0ACM8E7P9 A0ACM8E7P9 LOC115328108 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8029671|UniProtKB=A0ACM8DIJ5 A0ACM8DIJ5 LOC8029671 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121833266|UniProtKB=A0ACM8FK65 A0ACM8FK65 LOC121833266 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027103|UniProtKB=A0ACM8EAX7 A0ACM8EAX7 LOC8027103 PTHR12792:SF3 EXTRA SPINDLE POLES 1-RELATED SEPARIN cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 nuclear division#GO:0000280;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;chromosome separation#GO:0051304;meiotic chromosome segregation#GO:0045132;organelle organization#GO:0006996;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115315803|UniProtKB=A0ACM8DV77 A0ACM8DV77 LOC115315803 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836581|UniProtKB=A0ACM8FZ73 A0ACM8FZ73 LOC121836581 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031407|UniProtKB=A0ACM8EYQ3 A0ACM8EYQ3 LOC8031407 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121837732|UniProtKB=A0ACM8G686 A0ACM8G686 LOC121837732 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115316301|UniProtKB=A0ACM8EJC9 A0ACM8EJC9 LOC115316301 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8031714|UniProtKB=A0ACM8DIM4 A0ACM8DIM4 mRpS30 PTHR13014:SF3 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S30/P52 PRO-APOTOTIC PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML65 intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8034557|UniProtKB=A0ACM8DZA1 A0ACM8DZA1 PTHR11081:SF81 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE 1 5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;metal ion binding#GO:0046872;DNA endonuclease activity#GO:0004520;binding#GO:0005488;exonuclease activity#GO:0004527;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on DNA#GO:0140097;magnesium ion binding#GO:0000287;cation binding#GO:0043169;hydrolase activity#GO:0016787;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;ion binding#GO:0043167;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120840993|UniProtKB=A0ACM8EQK6 A0ACM8EQK6 LOC120840993 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC121048625|UniProtKB=A0ACM8FHH6 A0ACM8FHH6 LOC121048625 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314647|UniProtKB=A0ACM8DUG1 A0ACM8DUG1 LOC115314647 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310945|UniProtKB=A0ACM8DQ79 A0ACM8DQ79 LOC115310945 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115316337|UniProtKB=A0ACM8DWI3 A0ACM8DWI3 Efr PTHR10778:SF4 SOLUTE CARRIER FAMILY 35 MEMBER B NUCLEOTIDE SUGAR TRANSPORTER SLC35B4 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 nitrogen compound transport#GO:0071705;nucleotide-sugar transmembrane transport#GO:0015780;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115317695|UniProtKB=A0ACM8F4F3 A0ACM8F4F3 LOC115317695 PTHR22930:SF269 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316971|UniProtKB=A0ACM8DWI8 A0ACM8DWI8 LOC115316971 PTHR46557:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 10 protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8051675|UniProtKB=A0ACM8EA47 A0ACM8EA47 LOC8051675 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317300|UniProtKB=A0ACM8EQ36 A0ACM8EQ36 LOC115317300 PTHR24393:SF175 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8027877|UniProtKB=A0ACM8E394 A0ACM8E394 RnrS PTHR23409:SF18 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SMALL CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE SUBUNIT M2 metabolite interconversion enzyme#PC00262;reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921 IXOSC|EnsemblGenome=LOC115326243|UniProtKB=A0ACM8FCG6 A0ACM8FCG6 LOC115326243 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8051450|UniProtKB=A0ACM8G4K5 A0ACM8G4K5 LOC8051450 PTHR24411:SF55 NUCLEAR FACTOR ERYTHROID 2-RELATED FACTOR SEGMENTATION PROTEIN CAP'N'COLLAR double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC8052224|UniProtKB=A0ACM8DM34 A0ACM8DM34 Dbp80 PTHR47958:SF31 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;localization#GO:0051179 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC115317164|UniProtKB=A0ACM8F5C8 A0ACM8F5C8 LOC115317164 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838113|UniProtKB=A0ACM8G855 A0ACM8G855 LOC121838113 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033024|UniProtKB=A0ACM8FLW4 A0ACM8FLW4 LOC8033024 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046458|UniProtKB=A0ACM8G8E0 A0ACM8G8E0 LOC121046458 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8036402|UniProtKB=A0ACM8DSZ4 A0ACM8DSZ4 LOC8036402 PTHR46223:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE SETMAR chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8052836|UniProtKB=A0ACM8FWC9 A0ACM8FWC9 Mhcl PTHR45615:SF36 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN-LIKE, ISOFORM B-RELATED macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;ATP-dependent activity#GO:0140657;actin binding#GO:0003779;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC115316864|UniProtKB=A0ACM8FQE9 A0ACM8FQE9 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115317876|UniProtKB=A0ACM8DXH2 A0ACM8DXH2 LOC115317876 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC115330289|UniProtKB=A0ACM8EC16 A0ACM8EC16 LOC115330289 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115327418|UniProtKB=A0ACM8FP13 A0ACM8FP13 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC120849615|UniProtKB=A0ACM8F750 A0ACM8F750 LOC120849615 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC8042609|UniProtKB=A0ACM8FAP5 A0ACM8FAP5 Creld PTHR24038:SF11 STABILIN INTEGRIN BETA-LIKE PROTEIN E membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC115328116|UniProtKB=A0ACM8E956 A0ACM8E956 LOC115328116 PTHR31981:SF1 GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN GLYCOSYLATED LYSOSOMAL MEMBRANE PROTEIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8053617|UniProtKB=A0ACM8E1P0 A0ACM8E1P0 LOC8053617 PTHR13200:SF0 EEF1A LYSINE METHYLTRANSFERASE 1 EEF1A LYSINE METHYLTRANSFERASE 1 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;lysine N-methyltransferase activity#GO:0016278;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 IXOSC|EnsemblGenome=LOC120846715|UniProtKB=A0ACM8F3W3 A0ACM8F3W3 LOC120846715 PTHR45080:SF8 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE 1 ISOFORM X1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell junction organization#GO:0034330 axon#GO:0030424;membrane#GO:0016020;cell body#GO:0044297;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 IXOSC|EnsemblGenome=LOC8036307|UniProtKB=A0ACM8E6U7 A0ACM8E6U7 beg PTHR47170:SF2 MALONYL-COA ACP TRANSACYLASE, ACP-BINDING MALONYL-COA-ACYL CARRIER PROTEIN TRANSACYLASE IXOSC|EnsemblGenome=LOC120839517|UniProtKB=A0ACM8EMJ3 A0ACM8EMJ3 LOC120839517 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050849|UniProtKB=A0ACM8FAU8 A0ACM8FAU8 LOC8050849 PTHR10901:SF6 TROPOMODULIN TROPOMODULIN, ISOFORM N protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;actin filament organization#GO:0007015;system process#GO:0003008;cellular developmental process#GO:0048869;muscle contraction#GO:0006936;developmental process#GO:0032502;multicellular organismal process#GO:0032501;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular component organization or biogenesis#GO:0071840;cellular anatomical entity morphogenesis#GO:0032989;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;myofibril#GO:0030016;sarcomere#GO:0030017;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;contractile muscle fiber#GO:0043292;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115329809|UniProtKB=A0ACM8FAW1 A0ACM8FAW1 LOC115329809 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8043353|UniProtKB=A0ACM8F8M6 A0ACM8F8M6 LOC8043353 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115320097|UniProtKB=A0ACM8DZZ9 A0ACM8DZZ9 LOC115320097 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8023336|UniProtKB=A0ACM8DZT7 A0ACM8DZT7 LOC8023336 PTHR12429:SF8 NEURALIZED NEURALIZED-LIKE PROTEIN 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;developmental process#GO:0032502;cellular anatomical entity morphogenesis#GO:0032989;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;anatomical structure morphogenesis#GO:0009653;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;muscle cell development#GO:0055001;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;supramolecular fiber organization#GO:0097435;striated muscle cell development#GO:0055002;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;animal gross anatomical part developmental process#GO:0160108 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Notch signaling pathway#P00045>Neuralized#P01117 IXOSC|EnsemblGenome=LOC8029134|UniProtKB=A0ACM8F8J7 A0ACM8F8J7 LOC8029134 PTHR33748:SF5 PROTEIN CBG04600 GROUND-LIKE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115329216|UniProtKB=A0ACM8FUJ2 A0ACM8FUJ2 LOC115329216 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312583|UniProtKB=A0ACM8EGB9 A0ACM8EGB9 LOC115312583 PTHR21539:SF0 SAGA-ASSOCIATED FACTOR 29 SAGA-ASSOCIATED FACTOR 29 histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 IXOSC|EnsemblGenome=LOC121838395|UniProtKB=A0ACM8G8Y6 A0ACM8G8Y6 LOC121838395 PTHR35617:SF4 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN TYR RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053207|UniProtKB=A0ACM8ES64 A0ACM8ES64 PTHR14614:SF172 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115332210|UniProtKB=A0ACM8ED12 A0ACM8ED12 Rrp40 PTHR21321:SF1 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP40 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;snRNA metabolic process#GO:0016073;rRNA processing#GO:0006364;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;regulation of biological process#GO:0050789;snRNA 3'-end processing#GO:0034472;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;maturation of 5.8S rRNA#GO:0000460;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8038979|UniProtKB=A0ACM8E2J2 A0ACM8E2J2 LOC8038979 PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8025839|UniProtKB=A0ACM8EFH1 A0ACM8EFH1 Gnf1 PTHR23389:SF6 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 REPLICATION FACTOR C SUBUNIT 1 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8025935|UniProtKB=A0ACM8DGU3 A0ACM8DGU3 LOC8025935 PTHR11199:SF0 STROMAL ANTIGEN LD34181P-RELATED binding#GO:0005488;chromatin binding#GO:0003682 organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cohesin complex#GO:0008278;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8054027|UniProtKB=A0ACM8F7C2 A0ACM8F7C2 LOC8054027 PTHR10846:SF73 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER CG1090-RELATED potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873 establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120851186|UniProtKB=A0ACM8FBL7 A0ACM8FBL7 LOC120851186 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313547|UniProtKB=A0ACM8EII6 A0ACM8EII6 LOC115313547 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8033998|UniProtKB=A0ACM8E114 A0ACM8E114 LOC8033998 PTHR45840:SF8 RHOMBOID-RELATED PROTEIN RHOMBOID-4 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120848310|UniProtKB=A0ACM8F5G4 A0ACM8F5G4 LOC120848310 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121832928|UniProtKB=A0ACM8FLQ1 A0ACM8FLQ1 LOC121832928 PTHR24394:SF67 ZINC FINGER PROTEIN MYONEURIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115310083|UniProtKB=A0ACM8F6Q9 A0ACM8F6Q9 LOC115310083 PTHR31021:SF1 ADENOMATOSIS POLYPOSIS COLI DOWN-REGULATED 1 APCDD1 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038841|UniProtKB=A0ACM8E3C5 A0ACM8E3C5 Btk29A PTHR24418:SF479 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE BTK non-membrane spanning protein tyrosine kinase activity#GO:0004715;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 non-receptor tyrosine protein kinase#PC00168 IXOSC|EnsemblGenome=LOC115319210|UniProtKB=A0ACM8F7U9 A0ACM8F7U9 LOC115319210 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033029|UniProtKB=A0ACM8FLX7 A0ACM8FLX7 LOC8033029 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120840708|UniProtKB=A0ACM8EPV8 A0ACM8EPV8 LOC120840708 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=ISCI010018|UniProtKB=B7Q290 B7Q290 ISCW010018 PTHR41161:SF1 PROTEIN NCBP2AS2 PROTEIN NCBP2AS2 IXOSC|EnsemblGenome=LOC8024620|UniProtKB=A0ACM8DIF4 A0ACM8DIF4 LOC8024620 PTHR43272:SF113 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 ligase#PC00142 IXOSC|EnsemblGenome=LOC8034239|UniProtKB=A0ACM8DS76 A0ACM8DS76 LOC8034239 PTHR24252:SF7 ACROSIN-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-LIKE ISOFORM X1 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115312787|UniProtKB=A0ACM8FAE7 A0ACM8FAE7 ewg PTHR20338:SF8 NUCLEAR RESPIRATORY FACTOR 1 NUCLEAR RESPIRATORY FACTOR 1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121834846|UniProtKB=A0ACM8FS10 A0ACM8FS10 LOC121834846 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8026412|UniProtKB=A0ACM8DHR2 A0ACM8DHR2 RpL21 PTHR20981:SF6 60S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN EL21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8037788|UniProtKB=A0ACM8ECU0 A0ACM8ECU0 LOC8037788 PTHR11085:SF1 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-7 deacetylase activity#GO:0019213;histone modifying activity#GO:0140993;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC120844056|UniProtKB=A0ACM8G0L1 A0ACM8G0L1 LOC120844056 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8030515|UniProtKB=A0ACM8FUH2 A0ACM8FUH2 LOC8030515 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8034628|UniProtKB=A0ACM8FXU2 A0ACM8FXU2 LOC8034628 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8042034|UniProtKB=A0ACM8EEE2 A0ACM8EEE2 PTHR21347:SF0 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1L membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC115328060|UniProtKB=A0ACM8F5Z9 A0ACM8F5Z9 polo PTHR24345:SF93 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120847466|UniProtKB=A0ACM8F392 A0ACM8F392 LOC120847466 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115316094|UniProtKB=A0ACM8EHA6 A0ACM8EHA6 LOC115316094 PTHR13779:SF7 WERNER HELICASE-INTERACTING PROTEIN 1 FAMILY MEMBER ATPASE WRNIP1 isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;molecular function regulator activity#GO:0098772;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121048503|UniProtKB=A0ACM8FIC6 A0ACM8FIC6 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029514|UniProtKB=A0ACM8FHR9 A0ACM8FHR9 LOC8029514 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115316711|UniProtKB=A0ACM8DW66 A0ACM8DW66 LOC115316711 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8042288|UniProtKB=A0ACM8DRZ5 A0ACM8DRZ5 IP3K2 PTHR12400:SF26 INOSITOL POLYPHOSPHATE KINASE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137 IXOSC|EnsemblGenome=LOC115317596|UniProtKB=A0ACM8EYA4 A0ACM8EYA4 LOC115317596 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC-RELATED binding#GO:0005488;protein binding#GO:0005515 dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 IXOSC|EnsemblGenome=LOC8030401|UniProtKB=A0ACM8FZV2 A0ACM8FZV2 LOC8030401 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;carboxylic acid transmembrane transporter activity#GO:0046943 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120838843|UniProtKB=A0ACM8ELF1 A0ACM8ELF1 LOC120838843 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8028893|UniProtKB=A0ACM8E7W3 A0ACM8E7W3 LOC8028893 PTHR23080:SF63 THAP DOMAIN PROTEIN DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329495|UniProtKB=A0ACM8E9J7 A0ACM8E9J7 LOC115329495 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115319331|UniProtKB=A0ACM8DZ41 A0ACM8DZ41 LOC115319331 PTHR12931:SF15 UBIQUITIN THIOLESTERASE PROTEIN OTUB UBIQUITIN THIOESTERASE OTUBAIN-LIKE catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;ubiquitin binding#GO:0043130;protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488;deubiquitinase activity#GO:0101005 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8042496|UniProtKB=A0ACM8DRR1 A0ACM8DRR1 LOC8042496 PTHR14430:SF6 RABIN3-RELATED GDP_GTP EXCHANGE FACTOR SEC2 N-TERMINAL DOMAIN-CONTAINING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8033866|UniProtKB=A0ACM8ED60 A0ACM8ED60 LOC8033866 PTHR46957:SF3 CYTOKINE RECEPTOR PROTEIN-TYROSINE-PHOSPHATASE transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8033215|UniProtKB=A0ACM8EF83 A0ACM8EF83 LOC8033215 PTHR12358:SF111 SPHINGOSINE KINASE CERAMIDE KINASE, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;lipid kinase activity#GO:0001727 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 IXOSC|EnsemblGenome=LOC8033933|UniProtKB=A0ACM8F7R0 A0ACM8F7R0 Hr83 PTHR24083:SF155 NUCLEAR HORMONE RECEPTOR HORMONE RECEPTOR 83 sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 IXOSC|EnsemblGenome=LOC115327091|UniProtKB=A0ACM8ER27 A0ACM8ER27 LOC115327091 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034317|UniProtKB=A0ACM8EF58 A0ACM8EF58 LOC8034317 PTHR12231:SF278 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN KAPPA, ISOFORM A protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;synapse organization#GO:0050808;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 cell junction#GO:0030054;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120837621|UniProtKB=A0ACM8EIK5 A0ACM8EIK5 LOC120837621 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331627|UniProtKB=A0ACM8F3N4 A0ACM8F3N4 LOC115331627 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8034737|UniProtKB=A0ACM8G3Y7 A0ACM8G3Y7 Eip78C PTHR45805:SF12 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR RECEPTOR SUBFAMILY 1 GROUP D MEMBER 2A C4 zinc finger nuclear receptor#PC00169 IXOSC|EnsemblGenome=LOC8032824|UniProtKB=A0ACM8DQR0 A0ACM8DQR0 PTHR10113:SF10 PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 RNA binding#GO:0003723;translation factor activity#GO:0180051;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;translation#GO:0006412;translational termination#GO:0006415;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 translation factor#PC00223;translation release factor#PC00225 IXOSC|EnsemblGenome=LOC115312510|UniProtKB=A0ACM8F469 A0ACM8F469 LOC115312510 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 IXOSC|EnsemblGenome=LOC115315735|UniProtKB=A0ACM8DVS3 A0ACM8DVS3 LOC115315735 PTHR13538:SF4 N-ACETYLTRANSFERASE 6 N-ALPHA-ACETYLTRANSFERASE 80 catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;N-acetyltransferase activity#GO:0008080;small molecule binding#GO:0036094;anion binding#GO:0043168;acyltransferase activity#GO:0016746;ion binding#GO:0043167;transferase activity#GO:0016740;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;heterocyclic compound binding#GO:1901363;binding#GO:0005488;acetyltransferase activity#GO:0016407;nucleoside phosphate binding#GO:1901265;protein N-acyltransferase activity#GO:0140186 cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8051642|UniProtKB=A0ACM8DN97 A0ACM8DN97 PTHR11003:SF346 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 18 gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC120846798|UniProtKB=A0ACM8F444 A0ACM8F444 LOC120846798 PTHR47333:SF7 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120840490|UniProtKB=A0ACM8ENT1 A0ACM8ENT1 LOC120840490 PTHR33776:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025439|UniProtKB=A0ACM8FEP1 A0ACM8FEP1 norpA PTHR10336:SF214 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;lipase activity#GO:0016298 transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;metabolic process#GO:0008152;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;signal transduction#GO:0007165;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;transport#GO:0006810;establishment of localization#GO:0051234;organophosphate metabolic process#GO:0019637;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143 IXOSC|EnsemblGenome=LOC8029119|UniProtKB=A0ACM8DHN3 A0ACM8DHN3 LOC8029119 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115327318|UniProtKB=A0ACM8E6V2 A0ACM8E6V2 LOC115327318 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE-LIKE transferase#PC00220 IXOSC|EnsemblGenome=LOC8025947|UniProtKB=A0ACM8E694 A0ACM8E694 p115 PTHR10013:SF7 GENERAL VESICULAR TRANSPORT FACTOR P115 GENERAL VESICULAR TRANSPORT FACTOR P115 transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component organization#GO:0016043;membrane fusion#GO:0061025;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501 intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;Golgi stack#GO:0005795;intracellular vesicle#GO:0097708;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120848222|UniProtKB=A0ACM8FVX0 A0ACM8FVX0 LOC120848222 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 steroid hydroxylase activity#GO:0008395;binding#GO:0005488;tetrapyrrole binding#GO:0046906;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 steroid metabolic process#GO:0008202;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8033874|UniProtKB=A0ACM8E687 A0ACM8E687 LOC8033874 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115330426|UniProtKB=A0ACM8G1V0 A0ACM8G1V0 LOC115330426 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120848865|UniProtKB=A0ACM8F6V9 A0ACM8F6V9 LOC120848865 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310421|UniProtKB=A0ACM8EJM2 A0ACM8EJM2 LOC115310421 PTHR45689:SF5 I[[H]] CHANNEL, ISOFORM E I[[H]] CHANNEL, ISOFORM E monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC115310667|UniProtKB=A0ACM8DQ08 A0ACM8DQ08 LOC115310667 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115327076|UniProtKB=A0ACM8E821 A0ACM8E821 PTHR13278:SF0 ZINC FINGER PROTEIN 830 ZINC FINGER PROTEIN 830 signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;DNA replication checkpoint signaling#GO:0000076;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;mitotic DNA replication checkpoint signaling#GO:0033314;cell cycle process#GO:0022402;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;cellular response to stimulus#GO:0051716;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;intracellular signal transduction#GO:0035556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115323563|UniProtKB=A0ACM8E405 A0ACM8E405 LOC115332204 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC121838244|UniProtKB=A0ACM8G6Y9 A0ACM8G6Y9 LOC121838244 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8040661|UniProtKB=A0ACM8DH17 A0ACM8DH17 Nemp PTHR13598:SF1 AT07567P-RELATED AT07567P-RELATED intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC120849377|UniProtKB=A0ACM8F8M3 A0ACM8F8M3 LOC120849377 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115314401|UniProtKB=A0ACM8F6Z3 A0ACM8F6Z3 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC115325373|UniProtKB=A0ACM8E5R6 A0ACM8E5R6 bchs PTHR13743:SF146 BEIGE/BEACH-RELATED WD REPEAT AND FYVE DOMAIN-CONTAINING PROTEIN 3 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053342|UniProtKB=A0ACM8F585 A0ACM8F585 LOC8053342 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115330946|UniProtKB=A0ACM8EBG1 A0ACM8EBG1 LOC115330946 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120850579|UniProtKB=A0ACM8G6F4 A0ACM8G6F4 LOC120850579 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8036032|UniProtKB=A0ACM8G2J6 A0ACM8G2J6 LOC8036032 PTHR21636:SF2 PROTEIN DOK-7 PROTEIN DOK-7 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488 neuromuscular junction development#GO:0007528;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 IXOSC|EnsemblGenome=LOC8038839|UniProtKB=A0ACM8FUZ1 A0ACM8FUZ1 Dis3 PTHR23355:SF35 RIBONUCLEASE EXOSOME COMPLEX EXONUCLEASE RRP44 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;nuclear mRNA surveillance#GO:0071028;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC8029826|UniProtKB=A0ACM8DYB3 A0ACM8DYB3 LOC8029826 PTHR34339:SF2 STIMULATOR OF INTERFERON GENES PROTEIN STIMULATOR OF INTERFERON GENES PROTEIN HOMOLOG nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 positive regulation of macroautophagy#GO:0016239;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;cellular component assembly#GO:0022607;defense response to other organism#GO:0098542;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;positive regulation of autophagy#GO:0010508;organelle organization#GO:0006996;response to biotic stimulus#GO:0009607;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;regulation of macroautophagy#GO:0016241;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;response to external biotic stimulus#GO:0043207;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;vacuole organization#GO:0007033;organelle assembly#GO:0070925;biological regulation#GO:0065007;macroautophagy#GO:0016236;response to other organism#GO:0051707;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;reticulophagy#GO:0061709;regulation of metabolic process#GO:0019222;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;innate immune response#GO:0045087 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC120845802|UniProtKB=A0ACM8FUK1 A0ACM8FUK1 LOC120845802 PTHR47959:SF15 ATP-DEPENDENT RNA HELICASE RHLE-RELATED RNA HELICASE RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC120843723|UniProtKB=A0ACM8EWS8 A0ACM8EWS8 LOC120843723 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033343|UniProtKB=A0ACM8DHT6 A0ACM8DHT6 LOC8033343 PTHR31058:SF2 ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN ZINC FINGER C4H2 DOMAIN-CONTAINING PROTEIN multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of cell differentiation#GO:0045597;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;multicellular organismal process#GO:0032501;regulation of neuron differentiation#GO:0045664;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8035166|UniProtKB=A0ACM8E527 A0ACM8E527 PTHR24248:SF187 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OCTOPAMINE RECEPTOR BETA-2R signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8033790|UniProtKB=A0ACM8FWW1 A0ACM8FWW1 LOC8033790 PTHR23346:SF7 TRANSLATIONAL ACTIVATOR GCN1-RELATED STALLED RIBOSOME SENSOR GCN1 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;response to nutrient levels#GO:0031667;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;cellular response to amino acid starvation#GO:0034198;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to stress#GO:0033554 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8030941|UniProtKB=A0ACM8DSV6 A0ACM8DSV6 26-29-p PTHR12411:SF1075 CYSTEINE PROTEASE FAMILY C1-RELATED COUNTING FACTOR ASSOCIATED PROTEIN D hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8036270|UniProtKB=A0ACM8DJV2 A0ACM8DJV2 Mtl PTHR24072:SF399 RHO FAMILY GTPASE AT17867P purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 regulation of cell motility#GO:2000145;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;system development#GO:0048731;supramolecular fiber organization#GO:0097435;cortical cytoskeleton organization#GO:0030865;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;regulation of developmental process#GO:0050793;cellular developmental process#GO:0048869;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;Rac protein signal transduction#GO:0016601;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;signaling#GO:0023052;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component assembly#GO:0022607;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;multicellular organismal process#GO:0032501;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;axon guidance#GO:0007411;regulation of biological quality#GO:0065008;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell development#GO:0048468;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;cell projection assembly#GO:0030031 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 G-protein#PC00020;small GTPase#PC00208 Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;FGF signaling pathway#P00021>Rac#P00645 IXOSC|EnsemblGenome=LOC115316229|UniProtKB=A0ACM8F413 A0ACM8F413 LOC115316229 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053030|UniProtKB=A0ACM8DR60 A0ACM8DR60 thoc5 PTHR13375:SF3 FMS INTERACTING PROTEIN THO COMPLEX SUBUNIT 5 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription export complex#GO:0000346;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120849005|UniProtKB=A0ACM8F6R7 A0ACM8F6R7 LOC120849005 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8025807|UniProtKB=A0ACM8FKA1 A0ACM8FKA1 LOC8025807 PTHR12469:SF2 PROTEIN EMI5 HOMOLOG, MITOCHONDRIAL SUCCINATE DEHYDROGENASE ASSEMBLY FACTOR 2, MITOCHONDRIAL aerobic electron transport chain#GO:0019646;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;cellular component organization or biogenesis#GO:0071840;energy derivation by oxidation of organic compounds#GO:0015980;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;tricarboxylic acid cycle#GO:0006099;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex II assembly#GO:0034553 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC121834027|UniProtKB=A0ACM8FNP1 A0ACM8FNP1 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023860|UniProtKB=A0ACM8EQE0 A0ACM8EQE0 LOC8023860 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC8027593|UniProtKB=A0ACM8DW01 A0ACM8DW01 LOC8027593 PTHR11010:SF128 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8029177|UniProtKB=A0ACM8E8P6 A0ACM8E8P6 LOC8029177 PTHR15169:SF0 DAMAGE-SPECIFIC DNA BINDING PROTEIN 2 DNA DAMAGE-BINDING PROTEIN 2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;response to radiation#GO:0009314;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;response to UV#GO:0009411;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 damaged DNA-binding protein#PC00086 p53 pathway#P00059>p48#G04705 IXOSC|EnsemblGenome=LOC8033168|UniProtKB=A0ACM8E9K7 A0ACM8E9K7 LOC8033168 PTHR11157:SF126 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 4 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8030790|UniProtKB=A0ACM8DZK0 A0ACM8DZK0 LOC8030790 PTHR15668:SF5 JM1 PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 22 protein binding#GO:0005515;binding#GO:0005488 establishment of localization in cell#GO:0051649;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;positive regulation of macromolecule metabolic process#GO:0010604;vesicle-mediated transport#GO:0016192;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;endosomal transport#GO:0016197;regulation of biological process#GO:0050789;endocytic recycling#GO:0032456;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of metabolic process#GO:0009893;cellular localization#GO:0051641;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular transport#GO:0046907;vesicle-mediated transport to the plasma membrane#GO:0098876;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;localization within membrane#GO:0051668;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;localization#GO:0051179 IXOSC|EnsemblGenome=LOC8026219|UniProtKB=A0ACM8DHE3 A0ACM8DHE3 LOC8026219 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115316228|UniProtKB=A0ACM8DWE3 A0ACM8DWE3 LOC115316228 PTHR31699:SF1 NUDIX T16 FAMILY MEMBER U8 SNORNA-DECAPPING ENZYME RNA binding#GO:0003723;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;snoRNA binding#GO:0030515;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121047652|UniProtKB=A0ACM8FGJ3 A0ACM8FGJ3 LOC121047652 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115322661|UniProtKB=A0ACM8F3G6 A0ACM8F3G6 LOC115322661 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8040373|UniProtKB=A0ACM8EX06 A0ACM8EX06 Arfip PTHR12141:SF5 ARFAPTIN-RELATED ARFAPTIN molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 organelle#GO:0043226;cellular anatomical structure#GO:0110165;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC8052460|UniProtKB=A0ACM8E7L5 A0ACM8E7L5 LOC8052460 PTHR13254:SF0 GOLGI AUTOANTIGEN, GOLGIN SUBFAMILY A, 7 RAS MODIFICATION PROTEIN ERF4 protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8031970|UniProtKB=A0ACM8EBL8 A0ACM8EBL8 LOC8031970 PTHR48033:SF10 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN RNA-BINDING PROTEIN SQUID binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8023346|UniProtKB=A0ACM8DN96 A0ACM8DN96 LOC8023346 PTHR11200:SF310 INOSITOL 5-PHOSPHATASE LD06095P phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;ruffle#GO:0001726;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8043567|UniProtKB=A0ACM8DVM5 A0ACM8DVM5 LOC8043567 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120846439|UniProtKB=A0ACM8F240 A0ACM8F240 LOC120846439 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115310117|UniProtKB=A0ACM8G049 A0ACM8G049 LOC115310117 PTHR10166:SF67 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-1-LIKE monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;monoatomic cation channel activity#GO:0005261;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704 voltage-gated ion channel#PC00241;transporter#PC00227 IXOSC|EnsemblGenome=LOC120839914|UniProtKB=A0ACM8EME3 A0ACM8EME3 LOC120839914 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047089|UniProtKB=A0ACM8FE77 A0ACM8FE77 LOC121047089 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115319474|UniProtKB=A0ACM8DZC1 A0ACM8DZC1 LOC115319474 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8028480|UniProtKB=A0ACM8EWF3 A0ACM8EWF3 LOC8028480 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8024514|UniProtKB=A0ACM8DTU4 A0ACM8DTU4 LOC8024514 PTHR13621:SF2 PROLINE-RICH PROTEIN PRCC PROLINE-RICH PROTEIN PRCC intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115317657|UniProtKB=A0ACM8DXC5 A0ACM8DXC5 LOC115317657 PTHR15561:SF0 CALCITONIN GENE-RELATED PEPTIDE-RECEPTOR COMPONENT PROTEIN DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC9 transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120836780|UniProtKB=A0ACM8FA71 A0ACM8FA71 LOC8043783 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115312745|UniProtKB=A0ACM8EPJ1 A0ACM8EPJ1 LOC115312745 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314988|UniProtKB=A0ACM8DUE7 A0ACM8DUE7 LOC115314988 PTHR31489:SF2 LIN52 FAMILY MEMBER PROTEIN LIN-52 HOMOLOG IXOSC|EnsemblGenome=LOC115311981|UniProtKB=A0ACM8EFF1 A0ACM8EFF1 LOC115311981 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8051811|UniProtKB=A0ACM8DT36 A0ACM8DT36 LOC8051811 PTHR46514:SF3 AMPHIPHYSIN AMPHIPHYSIN binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8043062|UniProtKB=A0ACM8E6Z3 A0ACM8E6Z3 LOC8043062 PTHR24096:SF435 LONG-CHAIN-FATTY-ACID--COA LIGASE MALONATE--COA LIGASE ACSF3, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ligase#PC00142 IXOSC|EnsemblGenome=LOC8034181|UniProtKB=A0ACM8DY94 A0ACM8DY94 PIG-A PTHR45871:SF1 N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;phospholipid metabolic process#GO:0006644;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 membrane protein complex#GO:0098796;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC8053665|UniProtKB=A0ACM8DTE7 A0ACM8DTE7 LOC8053665 PTHR13932:SF5 COPROPORPHYRINIGEN III OXIDASE RADICAL S-ADENOSYL METHIONINE DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound metabolic process#GO:0006778;cellular process#GO:0009987;tetrapyrrole biosynthetic process#GO:0033014;porphyrin-containing compound biosynthetic process#GO:0006779;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidase#PC00175 Heme biosynthesis#P02746>Coproporphyrinogen oxidase (oxygen independent)#P02970 IXOSC|EnsemblGenome=LOC8037914|UniProtKB=A0ACM8EB00 A0ACM8EB00 LOC8037914 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8027658|UniProtKB=A0ACM8G144 A0ACM8G144 LOC8027658 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120839753|UniProtKB=A0ACM8EMH2 A0ACM8EMH2 LOC120839753 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8042791|UniProtKB=A0ACM8DKY9 A0ACM8DKY9 LOC8042791 PTHR12510:SF4 TROPONIN C-AKIN-1 PROTEIN GAMMA-GLUTAMYLAMINECYCLOTRANSFERASE cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC120846510|UniProtKB=A0ACM8F1R9 A0ACM8F1R9 LOC120846510 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC8034575|UniProtKB=A0ACM8FS76 A0ACM8FS76 Dtwd2 PTHR21392:SF0 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 2 IXOSC|EnsemblGenome=LOC8041347|UniProtKB=A0ACM8DWH4 A0ACM8DWH4 LOC8041347 PTHR13318:SF165 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN FBXL-1 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 IXOSC|EnsemblGenome=LOC115308574|UniProtKB=A0ACM8ES00 A0ACM8ES00 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8033487|UniProtKB=A0ACM8EM26 A0ACM8EM26 LOC8033487 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121837437|UniProtKB=A0ACM8G3L5 A0ACM8G3L5 LOC121837437 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023965|UniProtKB=A0ACM8DXP1 A0ACM8DXP1 LOC8023965 PTHR21314:SF0 QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE-RELATED QUEUOSINE 5'-PHOSPHATE N-GLYCOSYLASE_HYDROLASE cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 IXOSC|EnsemblGenome=LOC120846693|UniProtKB=A0ACM8F2Y6 A0ACM8F2Y6 LOC120846693 PTHR46186:SF2 CYSTATIN CYSTATIN-RELATED peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;vesicle#GO:0031982 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8033372|UniProtKB=A0ACM8FUW0 A0ACM8FUW0 LOC8033372 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8051141|UniProtKB=A0ACM8DNZ0 A0ACM8DNZ0 LOC8051141 PTHR20852:SF57 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE 2 CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 IXOSC|EnsemblGenome=LOC121046287|UniProtKB=A0ACM8FDQ5 A0ACM8FDQ5 LOC121046287 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032683|UniProtKB=A0ACM8EWQ1 A0ACM8EWQ1 LOC8032683 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121046366|UniProtKB=A0ACM8FDV9 A0ACM8FDV9 LOC121046366 PTHR39069:SF11 ECDYSONE-INDUCIBLE GENE E1, ISOFORM A EB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838858|UniProtKB=A0ACM8G0K9 A0ACM8G0K9 LOC120838858 PTHR22625:SF61 PLEXIN HEPATOCYTE GROWTH FACTOR RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;cell communication#GO:0007154;regulation of cell motility#GO:2000145;anatomical structure development#GO:0048856;system development#GO:0048731;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;signaling#GO:0023052;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;nervous system development#GO:0007399 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115332616|UniProtKB=A0ACM8F300 A0ACM8F300 LOC115332616 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115329341|UniProtKB=A0ACM8FR26 A0ACM8FR26 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043826|UniProtKB=A0ACM8E9K1 A0ACM8E9K1 LOC8043826 PTHR15454:SF75 NISCHARIN RELATED SERINE_THREONINE-PROTEIN KINASE 11-INTERACTING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120840758|UniProtKB=A0ACM8FT09 A0ACM8FT09 LOC120840758 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039682|UniProtKB=A0ACM8FVW8 A0ACM8FVW8 LOC8039682 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC120841668|UniProtKB=A0ACM8G831 A0ACM8G831 LOC120841668 PTHR24390:SF79 ZINC FINGER PROTEIN LD33778P double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120848163|UniProtKB=A0ACM8F6A5 A0ACM8F6A5 LOC120848163 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030920|UniProtKB=A0ACM8DHQ3 A0ACM8DHQ3 LOC8030920 PTHR11247:SF82 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 DOLICHYLDIPHOSPHATASE 1 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120846877|UniProtKB=A0ACM8F376 A0ACM8F376 LOC120846877 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839251|UniProtKB=A0ACM8FLK6 A0ACM8FLK6 LOC120839251 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833917|UniProtKB=A0ACM8FM73 A0ACM8FM73 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841823|UniProtKB=A0ACM8ES69 A0ACM8ES69 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024790|UniProtKB=A0ACM8DXM3 A0ACM8DXM3 Eogt PTHR20961:SF148 GLYCOSYLTRANSFERASE EGF DOMAIN-SPECIFIC O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120846041|UniProtKB=A0ACM8F0M6 A0ACM8F0M6 LOC120846041 PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115318912|UniProtKB=A0ACM8DZ09 A0ACM8DZ09 DNApol-epsilon255 PTHR10670:SF0 DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A DNA POLYMERASE EPSILON CATALYTIC SUBUNIT A catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity#GO:0016787;DNA-directed DNA polymerase activity#GO:0003887;transferase activity#GO:0016740;DNA exonuclease activity#GO:0004529;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895 DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;epsilon DNA polymerase complex#GO:0008622;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115310035|UniProtKB=A0ACM8EQK4 A0ACM8EQK4 LOC115310035 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115327363|UniProtKB=A0ACM8E7M6 A0ACM8E7M6 Prp6 PTHR11246:SF1 PRE-MRNA SPLICING FACTOR PRE-MRNA-PROCESSING FACTOR 6 spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120839700|UniProtKB=A0ACM8FK98 A0ACM8FK98 LOC120839700 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115319618|UniProtKB=A0ACM8ERE1 A0ACM8ERE1 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115308354|UniProtKB=A0ACM8DME2 A0ACM8DME2 LOC115308354 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836698|UniProtKB=A0ACM8FZ78 A0ACM8FZ78 LOC121836698 PTHR19443:SF16 HEXOKINASE HEXOKINASE-2-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;hexokinase activity#GO:0004396;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 Glycolysis#P00024>Hexokinase#P00677;Pentose phosphate pathway#P02762>Hexokinase#P03079;Fructose galactose metabolism#P02744>Hexokinase#P02966 IXOSC|EnsemblGenome=LOC8050473|UniProtKB=A0ACM8E4H0 A0ACM8E4H0 Snx16 PTHR22999:SF43 PX SERINE/THREONINE KINASE PXK SORTING NEXIN-16 phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167 cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;lysosomal transport#GO:0007041;endosome to lysosome transport#GO:0008333;metabolic process#GO:0008152;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;late endosome#GO:0005770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 IXOSC|EnsemblGenome=LOC8033617|UniProtKB=A0ACM8FVE3 A0ACM8FVE3 LOC8033617 PTHR20852:SF57 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE 2 CYTOPLASMIC catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 IXOSC|EnsemblGenome=LOC121833445|UniProtKB=A0ACM8FL54 A0ACM8FL54 LOC121833445 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328674|UniProtKB=A0ACM8FWJ4 A0ACM8FWJ4 LOC115328674 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030270|UniProtKB=A0ACM8DGK0 A0ACM8DGK0 RpLP0 PTHR45699:SF3 60S ACIDIC RIBOSOMAL PROTEIN P0 LARGE RIBOSOMAL SUBUNIT PROTEIN UL10 nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;binding#GO:0005488;RNA binding#GO:0003723;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8024675|UniProtKB=A0ACM8DII9 A0ACM8DII9 LOC8024675 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817 protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC8041278|UniProtKB=A0ACM8ECN1 A0ACM8ECN1 IFT52 PTHR12969:SF7 NGD5/OSM-6/IFT52 INTRAFLAGELLAR TRANSPORT PROTEIN 52 HOMOLOG microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;cilium assembly#GO:0060271;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120847850|UniProtKB=A0ACM8F4Q0 A0ACM8F4Q0 LOC120847850 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8053118|UniProtKB=A0ACM8DQP6 A0ACM8DQP6 LOC8053118 PTHR24256:SF470 TRYPTASE-RELATED SERINE PROTEASE 33 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115319697|UniProtKB=A0ACM8DZI8 A0ACM8DZI8 LOC115319697 PTHR10003:SF106 SUPEROXIDE DISMUTASE CU-ZN -RELATED SUPEROXIDE DISMUTASE [CU-ZN] transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;copper ion binding#GO:0005507;oxidoreductase activity#GO:0016491 cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;response to stress#GO:0006950;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120836198|UniProtKB=A0ACM8EPS4 A0ACM8EPS4 LOC120836198 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC115332803|UniProtKB=A0ACM8EUB2 A0ACM8EUB2 LOC115332803 PTHR13131:SF14 CYSTINOSIN CYSTINOSIN carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;vacuolar transmembrane transport#GO:0034486 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 secondary carrier transporter#PC00258;amino acid transporter#PC00046 IXOSC|EnsemblGenome=LOC120839086|UniProtKB=A0ACM8EKP1 A0ACM8EKP1 spn-A PTHR22942:SF39 RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER DNA REPAIR PROTEIN RAD51 HOMOLOG 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 nucleobase-containing compound metabolic process#GO:0006139;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;reproductive process#GO:0022414;homologous recombination#GO:0035825;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;organelle fission#GO:0048285;sexual reproduction#GO:0019953;mitotic recombination#GO:0006312;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;double-strand break repair#GO:0006302;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;protein-containing complex assembly#GO:0065003;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115310046|UniProtKB=A0ACM8DP89 A0ACM8DP89 LOC115310046 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115320180|UniProtKB=A0ACM8FMU8 A0ACM8FMU8 PTHR23055:SF167 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC121833296|UniProtKB=A0ACM8FK97 A0ACM8FK97 LOC121833296 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8038335|UniProtKB=A0ACM8DK57 A0ACM8DK57 LOC8038335 PTHR12290:SF19 CORNICHON-RELATED PROTEIN CORNICHON HOMOLOG 4 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115333113|UniProtKB=A0ACM8EEK0 A0ACM8EEK0 LOC115333113 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843191|UniProtKB=A0ACM8FTS8 A0ACM8FTS8 LOC120843191 PTHR10024:SF369 SYNAPTOTAGMIN FI18813P1 lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488;phospholipid binding#GO:0005543 synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;cellular process#GO:0009987;organelle organization#GO:0006996;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;regulation of localization#GO:0032879;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;export from cell#GO:0140352;signaling#GO:0023052;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;positive regulation of cellular process#GO:0048522;membrane fusion#GO:0061025;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;neurotransmitter secretion#GO:0007269;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;vesicle fusion#GO:0006906;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;regulation of exocytosis#GO:0017157;localization#GO:0051179;regulation of secretion#GO:0051046;cell communication#GO:0007154;secretion#GO:0046903 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;axon#GO:0030424;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cell junction#GO:0030054;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;neuron projection#GO:0043005 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 IXOSC|EnsemblGenome=LOC115332900|UniProtKB=A0ACM8EE88 A0ACM8EE88 LOC115332900 PTHR15995:SF1 PROTEIN ZWILCH HOMOLOG PROTEIN ZWILCH HOMOLOG regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;negative regulation of cell cycle#GO:0045786;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;regulation of chromosome separation#GO:1905818;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;negative regulation of chromosome organization#GO:2001251;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of mitotic sister chromatid separation#GO:0010965;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;intracellular protein localization#GO:0008104;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;protein localization to kinetochore#GO:0034501;macromolecule localization#GO:0033036;regulation of mitotic cell cycle#GO:0007346 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779 IXOSC|EnsemblGenome=LOC8043018|UniProtKB=A0ACM8E1X1 A0ACM8E1X1 LOC8043018 PTHR16112:SF16 METHYL-CPG BINDING PROTEIN, DROSOPHILA METHYL-CPG-BINDING DOMAIN PROTEIN 5_6 HOMOLOG SBA chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121045686|UniProtKB=A0ACM8FCV5 A0ACM8FCV5 LOC121045686 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8026541|UniProtKB=A0ACM8DHV4 A0ACM8DHV4 Dpm3 PTHR16433:SF0 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 3 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mannosyltransferase complex#GO:0031501;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090 transferase#PC00220 IXOSC|EnsemblGenome=LOC115312637|UniProtKB=A0ACM8DSB4 A0ACM8DSB4 LOC115312637 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115326640|UniProtKB=A0ACM8EMU0 A0ACM8EMU0 LOC115326640 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833424|UniProtKB=A0ACM8FLX5 A0ACM8FLX5 LOC121833424 PTHR12778:SF10 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED SOLUTE CARRIER FAMILY 33 MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC115322248|UniProtKB=A0ACM8FZE1 A0ACM8FZE1 LOC115322248 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833708|UniProtKB=A0ACM8FMH1 A0ACM8FMH1 LOC121833708 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115316206|UniProtKB=A0ACM8G8G3 A0ACM8G8G3 LOC115316206 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8051585|UniProtKB=A0ACM8DWX2 A0ACM8DWX2 LOC8051585 PTHR12775:SF0 PROTEIN C20ORF43 HOMOLOG REPLICATION TERMINATION FACTOR 2 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8041724|UniProtKB=A0ACM8E4M3 A0ACM8E4M3 LOC8041724 PTHR16099:SF5 8-OXO-DGTP DIPHOSPHATES NUDT15 NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15 IXOSC|EnsemblGenome=LOC115329506|UniProtKB=A0ACM8EPP5 A0ACM8EPP5 LOC115329506 PTHR42643:SF49 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120850590|UniProtKB=A0ACM8FAJ7 A0ACM8FAJ7 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041187|UniProtKB=A0ACM8G0J8 A0ACM8G0J8 LOC8041187 PTHR46109:SF1 PROTEIN LIN-28 PROTEIN LIN-28 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8028629|UniProtKB=A0ACM8E6Z1 A0ACM8E6Z1 LOC8028629 PTHR12411:SF1058 CYSTEINE PROTEASE FAMILY C1-RELATED DIPEPTIDYL PEPTIDASE 1 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8041887|UniProtKB=A0ACM8E2X5 A0ACM8E2X5 LOC8041887 PTHR12489:SF19 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 2 PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8039331|UniProtKB=A0ACM8DKC5 A0ACM8DKC5 RagC-D PTHR11259:SF2 RAS-RELATED GTP BINDING RAG/GTR YEAST GH16429P nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;response to stress#GO:0006950;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;negative regulation of catabolic process#GO:0009895;positive regulation of TOR signaling#GO:0032008;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;lysosome#GO:0005764;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8052209|UniProtKB=A0ACM8FAG8 A0ACM8FAG8 LOC8052209 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842659|UniProtKB=A0ACM8EUA7 A0ACM8EUA7 LOC120842659 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120840771|UniProtKB=A0ACM8ER53 A0ACM8ER53 LOC120840771 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837192|UniProtKB=A0ACM8G2Q0 A0ACM8G2Q0 LOC121837192 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837463|UniProtKB=A0ACM8G397 A0ACM8G397 LOC121837463 PTHR20938:SF0 INTEGRATOR COMPLEX SUBUNIT 4 INTEGRATOR COMPLEX SUBUNIT 4 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;transcription by RNA polymerase II#GO:0006366;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180 integrator complex#GO:0032039;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8028632|UniProtKB=A0ACM8E6P4 A0ACM8E6P4 RpS2 PTHR13718:SF4 RIBOSOMAL S SUBUNIT SMALL RIBOSOMAL SUBUNIT PROTEIN US5 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8035120|UniProtKB=A0ACM8DJR2 A0ACM8DJR2 LOC8035120 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293 transport#GO:0006810;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121833925|UniProtKB=A0ACM8FPK2 A0ACM8FPK2 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8040579|UniProtKB=A0ACM8DT07 A0ACM8DT07 eIF2Bgamma PTHR45989:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT GAMMA guanyl-nucleotide exchange factor activity#GO:0005085;translation factor activity#GO:0180051;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;translation initiation factor activity#GO:0003743;molecular function regulator activity#GO:0098772 translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC120839272|UniProtKB=A0ACM8EL20 A0ACM8EL20 LOC120839272 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848284|UniProtKB=A0ACM8F5S2 A0ACM8F5S2 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115317723|UniProtKB=A0ACM8DXV1 A0ACM8DXV1 LOC115317723 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115312039|UniProtKB=A0ACM8DRI0 A0ACM8DRI0 LOC115312039 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8037859|UniProtKB=A0ACM8E2S4 A0ACM8E2S4 LOC8037859 PTHR47219:SF28 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE USP6 N-TERMINAL-LIKE PROTEIN enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677 G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC121046520|UniProtKB=A0ACM8FE37 A0ACM8FE37 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8041409|UniProtKB=A0ACM8FB68 A0ACM8FB68 LOC8041409 PTHR11003:SF366 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 18 transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC115313191|UniProtKB=A0ACM8ELC3 A0ACM8ELC3 LOC120839507 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839233|UniProtKB=A0ACM8EMM1 A0ACM8EMM1 LOC120839233 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836669|UniProtKB=A0ACM8FZ28 A0ACM8FZ28 LOC121836669 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115323345|UniProtKB=A0ACM8E2X3 A0ACM8E2X3 LOC115323345 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053168|UniProtKB=A0ACM8DRJ0 A0ACM8DRJ0 LOC8053168 PTHR10351:SF23 TRANSCRIPTION FACTOR BTF3 FAMILY MEMBER TRANSCRIPTION FACTOR BTF3 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115319889|UniProtKB=A0ACM8E082 A0ACM8E082 LOC115319889 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323670|UniProtKB=A0ACM8EW11 A0ACM8EW11 LOC115323670 PTHR46015:SF1 ZGC:172121 BETAINE-HOMOCYSTEINE S-METHYLTRANSFERASE-RELATED transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024 IXOSC|EnsemblGenome=LOC121833180|UniProtKB=A0ACM8FJT7 A0ACM8FJT7 LOC121833180 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8035240|UniProtKB=A0ACM8DUF8 A0ACM8DUF8 Ak3 PTHR23359:SF242 NUCLEOTIDE KINASE GTP:AMP PHOSPHOTRANSFERASE, MITOCHONDRIAL transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776 nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 IXOSC|EnsemblGenome=LOC115332130|UniProtKB=A0ACM8EE58 A0ACM8EE58 LOC115332130 PTHR21451:SF0 HISTONE H3 METHYLTRANSFERASE HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170 DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;DNA integrity checkpoint signaling#GO:0031570;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;heterochromatin formation#GO:0031507;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of cell cycle#GO:0045786;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;constitutive heterochromatin formation#GO:0140719;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cell cycle checkpoint signaling#GO:0000075;cellular component assembly#GO:0022607;regulation of cell cycle process#GO:0010564;heterochromatin organization#GO:0070828;cellular response to stress#GO:0033554;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8033005|UniProtKB=A0ACM8EDC0 A0ACM8EDC0 PTHR16154:SF6 NEURABIN NEURABIN-1 IXOSC|EnsemblGenome=LOC115326075|UniProtKB=A0ACM8E5I3 A0ACM8E5I3 PTHR11158:SF29 MSF1/PX19 RELATED PRELI DOMAIN-CONTAINING PROTEIN 1, MITOCHONDRIAL lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 localization#GO:0051179;establishment of localization#GO:0051234;lipid localization#GO:0010876;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;phospholipid transport#GO:0015914;macromolecule localization#GO:0033036 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120849753|UniProtKB=A0ACM8F8E3 A0ACM8F8E3 Ttc7 PTHR23083:SF476 TETRATRICOPEPTIDE REPEAT PROTEIN, TPR TETRATRICOPEPTIDE REPEAT DOMAIN 7, ISOFORM A glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;macromolecule localization#GO:0033036;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;protein localization to membrane#GO:0072657;phosphorus metabolic process#GO:0006793;protein localization to plasma membrane#GO:0072659;primary metabolic process#GO:0044238;localization#GO:0051179;cellular localization#GO:0051641;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;localization within membrane#GO:0051668 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120841949|UniProtKB=A0ACM8ESF8 A0ACM8ESF8 LOC120841949 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024850|UniProtKB=A0ACM8DIQ4 A0ACM8DIQ4 LOC8024850 PTHR15160:SF17 VON HIPPEL-LINDAU PROTEIN VON HIPPEL-LINDAU DISEASE TUMOR SUPPRESSOR transcription corepressor activity#GO:0003714;molecular adaptor activity#GO:0060090;transcription coregulator activity#GO:0003712;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;transcription regulator activity#GO:0140110;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;proteasomal protein catabolic process#GO:0010498;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>VHL#P00816 IXOSC|EnsemblGenome=LOC115321078|UniProtKB=A0ACM8EZI1 A0ACM8EZI1 LOC115321078 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120838335|UniProtKB=A0ACM8F903 A0ACM8F903 LOC120849591 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316091|UniProtKB=A0ACM8DW06 A0ACM8DW06 PTHR11592:SF135 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554 peroxidase#PC00180;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120838976|UniProtKB=A0ACM8EM23 A0ACM8EM23 LOC120838976 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115312882|UniProtKB=A0ACM8EKQ7 A0ACM8EKQ7 LOC115312882 PTHR12072:SF4 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 1 molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 IXOSC|EnsemblGenome=LOC8052487|UniProtKB=A0ACM8DPT6 A0ACM8DPT6 LOC8052487 PTHR46176:SF1 LD21662P LD21662P IXOSC|EnsemblGenome=LOC8044017|UniProtKB=A0ACM8EDM6 A0ACM8EDM6 LOC8044017 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8040318|UniProtKB=A0ACM8DKK6 A0ACM8DKK6 LOC8040318 PTHR13829:SF2 SNRNP CORE PROTEIN FAMILY MEMBER U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM2 RNA binding#GO:0003723;snRNA binding#GO:0017069;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8025769|UniProtKB=A0ACM8EBH1 A0ACM8EBH1 Abi PTHR10460:SF68 ABL INTERACTOR FAMILY MEMBER ABELSON INTERACTING PROTEIN, ISOFORM D signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;neuron migration#GO:0001764;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cellular process#GO:0009987;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis#GO:0000902;cell motility#GO:0048870;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;lamellipodium#GO:0030027;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;cell leading edge#GO:0031252 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8026576|UniProtKB=A0ACM8F8A3 A0ACM8F8A3 LOC8026576 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 IXOSC|EnsemblGenome=LOC8034581|UniProtKB=A0ACM8E9G6 A0ACM8E9G6 LOC8034581 PTHR31281:SF3 PROTEIN FAM219A PROTEIN FAM219A IXOSC|EnsemblGenome=LOC8035444|UniProtKB=A0ACM8DM53 A0ACM8DM53 LOC8035444 PTHR48034:SF37 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED TRANSFORMER-2 SEX-DETERMINING PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120839489|UniProtKB=A0ACM8EMG1 A0ACM8EMG1 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024844|UniProtKB=A0ACM8EIY1 A0ACM8EIY1 LOC8024844 PTHR46143:SF1 CALPAIN-7 CALPAIN-7 endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 Huntington disease#P00029>Calpain#P00788 IXOSC|EnsemblGenome=LOC121838070|UniProtKB=A0ACM8G658 A0ACM8G658 LOC121838070 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8028599|UniProtKB=A0ACM8E1E5 A0ACM8E1E5 LOC8028599 PTHR12375:SF30 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN ALSIN2-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532 IXOSC|EnsemblGenome=LOC120843352|UniProtKB=A0ACM8EX03 A0ACM8EX03 LOC120843352 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029644|UniProtKB=A0ACM8ENE8 A0ACM8ENE8 Arl8 PTHR45732:SF23 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 8 cytoskeleton-dependent intracellular transport#GO:0030705;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088;endosomal transport#GO:0016197;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based movement#GO:0007018;anterograde axonal transport#GO:0008089;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;axonal transport#GO:0098930;lysosomal transport#GO:0007041 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 Huntington disease#P00029>ARF#P00786 IXOSC|EnsemblGenome=LOC120848672|UniProtKB=A0ACM8G3V5 A0ACM8G3V5 LOC120848672 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC120840421|UniProtKB=A0ACM8EP55 A0ACM8EP55 LOC120840421 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120836286|UniProtKB=A0ACM8FD77 A0ACM8FD77 GluClalpha PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC115329303|UniProtKB=A0ACM8EAS6 A0ACM8EAS6 LOC115329303 PTHR24399:SF70 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8025918|UniProtKB=A0ACM8DRN1 A0ACM8DRN1 LOC8025918 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115327713|UniProtKB=A0ACM8EQW7 A0ACM8EQW7 LOC115327713 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328522|UniProtKB=A0ACM8E9L3 A0ACM8E9L3 LOC115328522 PTHR28494:SF1 UPF0600 PROTEIN C5ORF51 RAB7A-INTERACTING MON1-CCZ1 COMPLEX SUBUNIT 1 IXOSC|EnsemblGenome=LOC8034555|UniProtKB=A0ACM8DZS0 A0ACM8DZS0 PTHR10749:SF8 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT BETA serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 IXOSC|EnsemblGenome=LOC120848637|UniProtKB=A0ACM8F623 A0ACM8F623 LOC120848637 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311542|UniProtKB=A0ACM8DR23 A0ACM8DR23 LOC115311542 PTHR21184:SF6 MENORIN (DENDRITIC BRANCHING PROTEIN) MENORIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8038309|UniProtKB=A0ACM8E4X4 A0ACM8E4X4 Cog4 PTHR24016:SF21 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 4 transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;cellular component organization#GO:0016043;organelle organization#GO:0006996;retrograde transport, vesicle recycling within Golgi#GO:0000301;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;Golgi organization#GO:0007030;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COG complex#GO:0017119 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121837129|UniProtKB=A0ACM8G3P0 A0ACM8G3P0 LOC121837129 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838628|UniProtKB=A0ACM8EL77 A0ACM8EL77 LOC120838628 PTHR10972:SF200 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9 lipid binding#GO:0008289;steroid binding#GO:0005496;binding#GO:0005488;sterol binding#GO:0032934 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8023540|UniProtKB=A0ACM8DSE4 A0ACM8DSE4 PH4alphaEFB PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 oxidoreductase complex#GO:1990204;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8023776|UniProtKB=A0ACM8DPQ6 A0ACM8DPQ6 LOC8023776 PTHR43757:SF20 AMINOMETHYLTRANSFERASE DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8026906|UniProtKB=A0ACM8DIH9 A0ACM8DIH9 PTHR13463:SF3 PROTEIN C10 PROTEIN C10 multicellular organism development#GO:0007275;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;developmental process#GO:0032502;post-embryonic development#GO:0009791 IXOSC|EnsemblGenome=LOC115325231|UniProtKB=A0ACM8ELE5 A0ACM8ELE5 LOC115325231 PTHR22872:SF9 BTK-BINDING PROTEIN-RELATED X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR IXOSC|EnsemblGenome=LOC115322732|UniProtKB=A0ACM8G0G4 A0ACM8G0G4 LOC115322732 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115315163|UniProtKB=A0ACM8G510 A0ACM8G510 LOC115315163 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8034142|UniProtKB=A0ACM8DJ12 A0ACM8DJ12 Hexim PTHR13469:SF8 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 HEXIM P-TEFB COMPLEX SUBUNIT 1 RNA binding#GO:0003723;enzyme regulator activity#GO:0030234;snRNA binding#GO:0017069;molecular function inhibitor activity#GO:0140678;binding#GO:0005488;nucleic acid binding#GO:0003676;kinase inhibitor activity#GO:0019210;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8024290|UniProtKB=A0ACM8FEV0 A0ACM8FEV0 LOC8024290 PTHR46342:SF1 ALPHA-CATULIN ALPHA-CATULIN cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154 Wnt signaling pathway#P00057>alpha-catenin#P01471 IXOSC|EnsemblGenome=LOC115331080|UniProtKB=A0ACM8F1J3 A0ACM8F1J3 LOC115331080 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046615|UniProtKB=A0ACM8FD70 A0ACM8FD70 LOC121046615 PTHR15362:SF13 PHOSPHATIDYLINOSITOL SYNTHASE SI:CH1073-145M9.1 transferase#PC00220 IXOSC|EnsemblGenome=LOC120844285|UniProtKB=A0ACM8EZF4 A0ACM8EZF4 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028892|UniProtKB=A0ACM8E6X8 A0ACM8E6X8 LOC8028892 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC115326539|UniProtKB=A0ACM8E6T5 A0ACM8E6T5 LOC115326539 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121048049|UniProtKB=A0ACM8FIF5 A0ACM8FIF5 LOC121048049 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028819|UniProtKB=A0ACM8DH89 A0ACM8DH89 LOC8028819 PTHR12447:SF39 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13C molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121837502|UniProtKB=A0ACM8G3Q7 A0ACM8G3Q7 LOC121837502 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115321119|UniProtKB=A0ACM8E102 A0ACM8E102 Mettl5 PTHR23290:SF0 RRNA N6-ADENOSINE-METHYLTRANSFERASE METTL5 RRNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL5 catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167 IXOSC|EnsemblGenome=LOC8036763|UniProtKB=A0ACM8DRJ2 A0ACM8DRJ2 LOC8036763 PTHR11089:SF9 GTP-BINDING PROTEIN-RELATED NUCLEOLAR GTP-BINDING PROTEIN 2 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8030859|UniProtKB=A0ACM8FVN9 A0ACM8FVN9 LOC8030859 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8031512|UniProtKB=A0ACM8DIB1 A0ACM8DIB1 LOC8031512 PTHR43206:SF1 AMINOTRANSFERASE 4-AMINOBUTYRATE AMINOTRANSFERASE, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 Pyrimidine Metabolism#P02771>Aminotransferase#P03129;Aminobutyrate degradation#P02726>4-aminobutyrate aminotransferase#P02825;Gamma-aminobutyric acid synthesis#P04384>GABA aminotransferase#P04480 IXOSC|EnsemblGenome=LOC8053594|UniProtKB=A0ACM8DRY3 A0ACM8DRY3 LOC8053594 PTHR12271:SF141 POLY A POLYMERASE CID PAP -RELATED TERMINAL URIDYLYLTRANSFERASE TAILOR catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604 nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC8042709|UniProtKB=A0ACM8E2C9 A0ACM8E2C9 LOC8042709 PTHR11730:SF58 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;homeostatic process#GO:0042592;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC115320904|UniProtKB=A0ACM8F8G1 A0ACM8F8G1 LOC115320904 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837674|UniProtKB=A0ACM8G4K3 A0ACM8G4K3 LOC121837674 PTHR19303:SF57 TRANSPOSON POGO TRANSPOSABLE ELEMENT WITH KRAB DOMAIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120838400|UniProtKB=A0ACM8EKJ2 A0ACM8EKJ2 LOC120838400 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115320128|UniProtKB=A0ACM8E0Y6 A0ACM8E0Y6 PTHR23359:SF111 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 5 phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;nucleoside diphosphate metabolic process#GO:0009132;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;ribonucleoside diphosphate metabolic process#GO:0009185;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 nucleotide kinase#PC00172;kinase#PC00137 IXOSC|EnsemblGenome=LOC115323779|UniProtKB=A0ACM8E463 A0ACM8E463 LOC115323779 PTHR45618:SF69 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 7 proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 response to temperature stimulus#GO:0009266;multicellular organismal process#GO:0032501;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;response to stress#GO:0006950;multicellular organismal-level homeostasis#GO:0048871;establishment of localization#GO:0051234;transport#GO:0006810;temperature homeostasis#GO:0001659;intracellular transport#GO:0046907;homeostatic process#GO:0042592;response to cold#GO:0009409;mitochondrial transport#GO:0006839;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;adaptive thermogenesis#GO:1990845 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115311201|UniProtKB=A0ACM8DQJ5 A0ACM8DQJ5 LOC115311201 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115310330|UniProtKB=A0ACM8F762 A0ACM8F762 LOC115310330 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115308425|UniProtKB=A0ACM8DME9 A0ACM8DME9 mRpL52 PTHR34090:SF1 39S RIBOSOMAL PROTEIN L52, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML52 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC121833118|UniProtKB=A0ACM8FIB0 A0ACM8FIB0 LOC121833118 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120839499|UniProtKB=A0ACM8EMH6 A0ACM8EMH6 LOC120839499 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120847683|UniProtKB=A0ACM8FVI1 A0ACM8FVI1 LOC120847683 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120850462|UniProtKB=A0ACM8F9W4 A0ACM8F9W4 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular process#GO:0009987;circulatory system development#GO:0072359;heart development#GO:0007507;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 IXOSC|EnsemblGenome=LOC8050717|UniProtKB=A0ACM8DMZ5 A0ACM8DMZ5 LOC8050717 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121837461|UniProtKB=A0ACM8G4X7 A0ACM8G4X7 LOC121837461 PTHR45858:SF5 FERM DOMAIN CONTAINING PROTEIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 IXOSC|EnsemblGenome=LOC8033730|UniProtKB=A0ACM8DY45 A0ACM8DY45 LOC8033730 PTHR15415:SF7 MITOFILIN MICOS COMPLEX SUBUNIT MIC60 IXOSC|EnsemblGenome=LOC8026585|UniProtKB=A0ACM8DI04 A0ACM8DI04 LOC8026585 PTHR12270:SF52 GLYCOSYLTRANSFERASE-RELATED GLYCOSYLTRANSFERASE-LIKE PROTEIN GNT13-RELATED hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;glucuronosyltransferase activity#GO:0015020;xylosyltransferase activity#GO:0042285 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115327906|UniProtKB=A0ACM8EHH6 A0ACM8EHH6 LOC115327906 PTHR23430:SF50 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789 organelle#GO:0043226;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8041299|UniProtKB=A0ACM8ECY1 A0ACM8ECY1 LOC8041299 PTHR13123:SF7 LD30288P LD30288P post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115310369|UniProtKB=A0ACM8DPN1 A0ACM8DPN1 RpS7 PTHR11278:SF0 40S RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN ES7 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;ribosome#GO:0005840 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8031031|UniProtKB=A0ACM8ET50 A0ACM8ET50 LOC8031031 PTHR43615:SF1 PHOSPHOENOLPYRUVATE SYNTHASE-RELATED PHOSPHOENOLPYRUVATE SYNTHASE IXOSC|EnsemblGenome=LOC8038603|UniProtKB=A0ACM8DXE0 A0ACM8DXE0 LOC8038603 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115324772|UniProtKB=A0ACM8ERT8 A0ACM8ERT8 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8052405|UniProtKB=A0ACM8EDF7 A0ACM8EDF7 LOC8052405 PTHR22950:SF652 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810;amino acid transport#GO:0006865 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;amino acid transporter#PC00046 IXOSC|EnsemblGenome=LOC8029436|UniProtKB=A0ACM8E3K5 A0ACM8E3K5 LOC8029436 PTHR12983:SF9 RING FINGER 10 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RNF10 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8032791|UniProtKB=A0ACM8DGV9 A0ACM8DGV9 LOC8032791 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8037499|UniProtKB=A0ACM8DRS8 A0ACM8DRS8 Mad PTHR13703:SF61 SMAD PROTEIN MOTHERS AGAINST DPP DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cellular response to BMP stimulus#GO:0071773;cellular process#GO:0009987;signal transduction#GO:0007165;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 SCW signaling pathway#P06216>MED#P06323;DPP signaling pathway#P06213>MAD#P06288;GBB signaling pathway#P06214>MED#P06299;MYO signaling pathway#P06215>MED#P06311;DPP signaling pathway#P06213>MED#P06279;Wnt signaling pathway#P00057>Smad4#P01455;DPP-SCW signaling pathway#P06212>MAD#P06271;DPP-SCW signaling pathway#P06212>MED#P06265;SCW signaling pathway#P06216>MAD#P06331;ALP23B signaling pathway#P06209>MED#P06221;Activin beta signaling pathway#P06210>MED#P06233;GBB signaling pathway#P06214>MAD#P06305;TGF-beta signaling pathway#P00052>RSmads#P01292;BMP/activin signaling pathway-drosophila#P06211>R-Smad#P06245 IXOSC|EnsemblGenome=LOC8051354|UniProtKB=A0ACM8FTH3 A0ACM8FTH3 LOC8051354 PTHR47971:SF28 KINESIN-RELATED PROTEIN 6 KINESIN-LIKE PROTEIN KIF2A ISOFORM X1 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC8028070|UniProtKB=A0ACM8DJL1 A0ACM8DJL1 LOC8028070 PTHR11134:SF4 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-4 COMPLEX SUBUNIT BETA-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;AP-type membrane coat adaptor complex#GO:0030119;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8023855|UniProtKB=A0ACM8FB62 A0ACM8FB62 LOC8023855 PTHR31569:SF7 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZSWIM1_3 RNASEH-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028811|UniProtKB=A0ACM8DQC4 A0ACM8DQC4 LOC8028811 PTHR24394:SF67 ZINC FINGER PROTEIN MYONEURIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120837047|UniProtKB=A0ACM8EGG5 A0ACM8EGG5 Sfp24F PTHR22799:SF6 TETRANECTIN-RELATED COLLECTIN-11-LIKE intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC115312222|UniProtKB=A0ACM8FEX3 A0ACM8FEX3 LOC115312222 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331124|UniProtKB=A0ACM8ECN2 A0ACM8ECN2 LOC115331124 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115308326|UniProtKB=A0ACM8DMC6 A0ACM8DMC6 LOC115308326 PTHR10865:SF29 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA3 binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;protein binding#GO:0005515;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;histone deacetylase binding#GO:0042826;transcription coactivator activity#GO:0003713 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 p53 pathway#P00059>MTA2#P04615 IXOSC|EnsemblGenome=LOC115327397|UniProtKB=A0ACM8E7N2 A0ACM8E7N2 LOC115327397 PTHR46573:SF1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8026898|UniProtKB=A0ACM8E0I5 A0ACM8E0I5 PTHR13924:SF13 TRANSFORMING ACIDIC COILED-COIL CONTAINING PROTEIN 1/2 TRANSFORMING ACIDIC COILED-COIL PROTEIN, ISOFORM K establishment of localization#GO:0051234;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;supramolecular fiber organization#GO:0097435;organelle localization#GO:0051640;establishment of organelle localization#GO:0051656;cytoplasmic microtubule organization#GO:0031122;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;nuclear migration#GO:0007097 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819 IXOSC|EnsemblGenome=LOC115309136|UniProtKB=A0ACM8F0R4 A0ACM8F0R4 LOC115309136 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8038434|UniProtKB=A0ACM8DK64 A0ACM8DK64 LOC8038434 PTHR23382:SF34 MALATE DEHYDROGENASE MALATE DEHYDROGENASE, CYTOPLASMIC oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 TCA cycle#P00051>Malate Dehydrogenase#P01270 IXOSC|EnsemblGenome=LOC8036065|UniProtKB=A0ACM8ETI6 A0ACM8ETI6 LOC8036065 PTHR10117:SF54 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN binding#GO:0005488;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 IXOSC|EnsemblGenome=LOC121837339|UniProtKB=A0ACM8G385 A0ACM8G385 LOC121837339 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8037074|UniProtKB=A0ACM8F0Z2 A0ACM8F0Z2 LOC8037074 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115332553|UniProtKB=A0ACM8EDD0 A0ACM8EDD0 LOC115332553 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115325132|UniProtKB=A0ACM8E5D1 A0ACM8E5D1 LOC115325132 PTHR12692:SF8 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE-RELATED GH11935P protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;protein metabolic process#GO:0019538;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;monoatomic ion transmembrane transport#GO:0034220;biosynthetic process#GO:0009058;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;glycoprotein metabolic process#GO:0009100;magnesium ion transport#GO:0015693;metabolic process#GO:0008152;establishment of localization#GO:0051234;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8052190|UniProtKB=A0ACM8G6E6 A0ACM8G6E6 LOC8052190 PTHR11339:SF416 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED HEMOLECTIN, ISOFORM A extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC120848139|UniProtKB=A0ACM8F692 A0ACM8F692 LOC120848139 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8051360|UniProtKB=A0ACM8DLU0 A0ACM8DLU0 LOC8051360 PTHR20835:SF0 E3 UBIQUITIN-PROTEIN LIGASE PPP1R11-RELATED E3 UBIQUITIN-PROTEIN LIGASE PPP1R11 protein phosphatase binding#GO:0019903;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8029689|UniProtKB=A0ACM8DVD1 A0ACM8DVD1 wcd PTHR18359:SF0 WD-REPEAT PROTEIN-RELATED U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 18 HOMOLOG ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040 IXOSC|EnsemblGenome=LOC115310946|UniProtKB=A0ACM8FIY4 A0ACM8FIY4 LOC115310946 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121837001|UniProtKB=A0ACM8G2H1 A0ACM8G2H1 LOC121837001 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330927|UniProtKB=A0ACM8G6I5 A0ACM8G6I5 LOC115330927 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120844514|UniProtKB=A0ACM8EYY0 A0ACM8EYY0 LOC120844514 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023237|UniProtKB=A0ACM8E5A6 A0ACM8E5A6 LOC8023237 PTHR35259:SF3 BOMBESIN RECEPTOR-ACTIVATED PROTEIN C6ORF89 MECH2 PROTEIN IXOSC|EnsemblGenome=LOC8032949|UniProtKB=A0ACM8DW14 A0ACM8DW14 LOC8032949 PTHR45625:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYLPROLYL ISOMERASE DOMAIN AND WD REPEAT-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115314087|UniProtKB=A0ACM8ELI6 A0ACM8ELI6 LOC115314087 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8023850|UniProtKB=A0ACM8EFT4 A0ACM8EFT4 LOC8023850 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8033385|UniProtKB=A0ACM8E271 A0ACM8E271 LOC8033385 PTHR14003:SF37 TRANSCRIPTIONAL REPRESSOR PROTEIN YY YY2 TRANSCRIPTION FACTOR sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell development#GO:0048468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;PcG protein complex#GO:0031519 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115314318|UniProtKB=A0ACM8FWF7 A0ACM8FWF7 LOC115314318 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115323404|UniProtKB=A0ACM8E474 A0ACM8E474 LOC115323404 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8034057|UniProtKB=A0ACM8DIV2 A0ACM8DIV2 LOC8034057 PTHR31840:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 COILED-COIL DOMAIN-CONTAINING PROTEIN 97 IXOSC|EnsemblGenome=LOC8029226|UniProtKB=A0ACM8DHU5 A0ACM8DHU5 Vkor PTHR14519:SF9 VITAMIN K EPOXIDE REDUCTASE COMPLEX, SUBUNIT 1 VITAMIN-K-EPOXIDE REDUCTASE (WARFARIN-SENSITIVE) catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;ketone metabolic process#GO:0042180;vitamin K metabolic process#GO:0042373;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115324640|UniProtKB=A0ACM8F4S5 A0ACM8F4S5 LOC115324640 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115328035|UniProtKB=A0ACM8E7K2 A0ACM8E7K2 LOC115328035 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052143|UniProtKB=A0ACM8G2U4 A0ACM8G2U4 LOC8052143 PTHR24346:SF122 MAP/MICROTUBULE AFFINITY-REGULATING KINASE MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8029898|UniProtKB=A0ACM8E162 A0ACM8E162 LOC8029898 PTHR12305:SF99 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE TPTE2-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 protein modifying enzyme#PC00260;protein phosphatase#PC00195 Hypoxia response via HIF activation#P00030>PTEN#P00824;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480;p53 pathway feedback loops 2#P04398>PTEN#P04658;p53 pathway#P00059>PTEN#G01579;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;p53 pathway feedback loops 2#P04398>PTEN#G04714 IXOSC|EnsemblGenome=LOC120837729|UniProtKB=A0ACM8EHM9 A0ACM8EHM9 LOC120849068 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043016|UniProtKB=A0ACM8FZU6 A0ACM8FZU6 LOC8043016 PTHR12309:SF5 SEC61 GAMMA SUBUNIT PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031;localization within membrane#GO:0051668 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum#GO:0005791;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8052626|UniProtKB=A0ACM8DLZ8 A0ACM8DLZ8 Vps26 PTHR12233:SF1 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;vesicle-mediated transport#GO:0016192;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;cytosolic transport#GO:0016482 membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;retromer complex#GO:0030904;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8034034|UniProtKB=A0ACM8G7D5 A0ACM8G7D5 LOC8034034 PTHR11817:SF3 PYRUVATE KINASE AT14039P-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;pyruvate kinase activity#GO:0004743;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;nicotinamide nucleotide metabolic process#GO:0046496;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;oxoacid metabolic process#GO:0043436;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;carbohydrate catabolic process#GO:0016052;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;purine nucleotide metabolic process#GO:0006163;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;small molecule metabolic process#GO:0044281;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;nucleotide catabolic process#GO:0009166;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;nucleobase-containing compound metabolic process#GO:0006139;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;primary metabolic process#GO:0044238;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase#PC00137 Pyruvate metabolism#P02772>Pyruvate Kinase#P03132 IXOSC|EnsemblGenome=LOC8039975|UniProtKB=A0ACM8ETC9 A0ACM8ETC9 LOC8039975 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC121832973|UniProtKB=A0ACM8FPT3 A0ACM8FPT3 LOC121832973 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120847382|UniProtKB=A0ACM8F3X5 A0ACM8F3X5 LOC120847382 PTHR24346:SF112 MAP/MICROTUBULE AFFINITY-REGULATING KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120840627|UniProtKB=A0ACM8EPW6 A0ACM8EPW6 LOC120840627 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028090|UniProtKB=A0ACM8FJU7 A0ACM8FJU7 LOC8028090 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120849525|UniProtKB=A0ACM8FJK0 A0ACM8FJK0 LOC120849525 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115315306|UniProtKB=A0ACM8FS95 A0ACM8FS95 LOC115315306 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8037664|UniProtKB=A0ACM8DM65 A0ACM8DM65 Papst2 PTHR10778:SF8 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 2 purine nucleotide transmembrane transporter activity#GO:0015216;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115309205|UniProtKB=A0ACM8FB87 A0ACM8FB87 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8023321|UniProtKB=A0ACM8F5N6 A0ACM8F5N6 LOC8023321 PTHR43107:SF27 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN-FATTY-ACID--COA LIGASE ligase activity, forming carbon-sulfur bonds#GO:0016877;carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;monocarboxylic acid transmembrane transporter activity#GO:0008028;catalytic activity#GO:0003824;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874 cellular process#GO:0009987;long-chain fatty acid metabolic process#GO:0001676;macromolecule localization#GO:0033036;lipid transport#GO:0006869;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;carboxylic acid transport#GO:0046942;transport#GO:0006810;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;import into cell#GO:0098657;establishment of localization#GO:0051234;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120844054|UniProtKB=A0ACM8EXE6 A0ACM8EXE6 LOC120844054 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053355|UniProtKB=A0ACM8DLR8 A0ACM8DLR8 LOC8053355 PTHR22890:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 11 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592 IXOSC|EnsemblGenome=LOC8026744|UniProtKB=A0ACM8EWG9 A0ACM8EWG9 LOC8026744 PTHR43272:SF118 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;oxoacid metabolic process#GO:0043436;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;organophosphate metabolic process#GO:0019637;long-chain fatty acid metabolic process#GO:0001676;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nucleobase-containing compound metabolic process#GO:0006139;nervous system development#GO:0007399;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;neuron differentiation#GO:0030182;developmental process#GO:0032502;lipid metabolic process#GO:0006629;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;neurogenesis#GO:0022008 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 ligase#PC00142 IXOSC|EnsemblGenome=LOC120840996|UniProtKB=A0ACM8G6W2 A0ACM8G6W2 LOC120840996 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120842135|UniProtKB=A0ACM8FF80 A0ACM8FF80 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844210|UniProtKB=A0ACM8EY83 A0ACM8EY83 LOC120844210 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318098|UniProtKB=A0ACM8DYE8 A0ACM8DYE8 Irbp PTHR12604:SF2 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU70 nucleic acid binding#GO:0003676;binding#GO:0005488;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;double-strand break repair via nonhomologous end joining#GO:0006303;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8030467|UniProtKB=A0ACM8E6S4 A0ACM8E6S4 LOC8030467 PTHR10015:SF427 HEAT SHOCK TRANSCRIPTION FACTOR HEAT SHOCK FACTOR PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC121047624|UniProtKB=A0ACM8FGP3 A0ACM8FGP3 LOC121047624 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115314382|UniProtKB=A0ACM8FIL9 A0ACM8FIL9 LOC121833212 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120839562|UniProtKB=A0ACM8EMA2 A0ACM8EMA2 LOC120839562 PTHR16852:SF2 GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8036804|UniProtKB=A0ACM8EYN2 A0ACM8EYN2 LOC8036804 PTHR24006:SF722 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 48 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC120850477|UniProtKB=A0ACM8FA85 A0ACM8FA85 LOC120850477 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115332421|UniProtKB=A0ACM8EE64 A0ACM8EE64 LOC115332421 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121835830|UniProtKB=A0ACM8FVY5 A0ACM8FVY5 LOC121835830 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309290|UniProtKB=A0ACM8FTC5 A0ACM8FTC5 LOC115309290 PTHR12916:SF15 CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2 UNINFLATABLE, ISOFORM C signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;Notch signaling pathway#GO:0007219 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC115312730|UniProtKB=A0ACM8FDC3 A0ACM8FDC3 LOC115312730 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC120843485|UniProtKB=A0ACM8EWA1 A0ACM8EWA1 LOC8053155 PTHR15588:SF9 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM8 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U6 snRNP#GO:0005688 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120848421|UniProtKB=A0ACM8F5Q3 A0ACM8F5Q3 LOC120848421 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8038303|UniProtKB=A0ACM8EEZ3 A0ACM8EEZ3 LOC8038303 PTHR43829:SF33 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-9 carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372 carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987;organic hydroxy compound transport#GO:0015850;fluid transport#GO:0042044;water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate transport#GO:0008643;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 IXOSC|EnsemblGenome=LOC121048293|UniProtKB=A0ACM8FI15 A0ACM8FI15 LOC121048293 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321495|UniProtKB=A0ACM8E2A7 A0ACM8E2A7 LOC121836270 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037557|UniProtKB=A0ACM8DTX1 A0ACM8DTX1 Hacd2 PTHR11035:SF35 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 dehydratase#PC00091 IXOSC|EnsemblGenome=LOC115323193|UniProtKB=A0ACM8E3F3 A0ACM8E3F3 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8024500|UniProtKB=A0ACM8EFZ7 A0ACM8EFZ7 RhoGAPp190 PTHR46005:SF4 RHO GTPASE-ACTIVATING PROTEIN 190 RHO GTPASE-ACTIVATING PROTEIN 190 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;regulation of cell size#GO:0008361;intracellular signal transduction#GO:0035556;regulation of biological quality#GO:0065008;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;signal transduction#GO:0007165;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of axonogenesis#GO:0050770;regulation of cell projection organization#GO:0031344;regulation of anatomical structure size#GO:0090066 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 IXOSC|EnsemblGenome=LOC8024189|UniProtKB=A0ACM8FRJ9 A0ACM8FRJ9 LOC8024189 PTHR24112:SF66 LEUCINE-RICH REPEAT, ISOFORM F-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 37 HOMOLOG regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789 cell leading edge#GO:0031252;membrane#GO:0016020;cell periphery#GO:0071944;lamellipodium#GO:0030027;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8037322|UniProtKB=A0ACM8DK12 A0ACM8DK12 LOC8037322 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC120838448|UniProtKB=A0ACM8EJA9 A0ACM8EJA9 LOC120838448 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8043086|UniProtKB=A0ACM8DZE5 A0ACM8DZE5 CysRS-m PTHR10890:SF27 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, MITOCHONDRIAL-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC115329657|UniProtKB=A0ACM8EVI1 A0ACM8EVI1 LOC115329657 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848660|UniProtKB=A0ACM8F6H0 A0ACM8F6H0 LOC120848660 PTHR11530:SF11 D-AMINO ACID OXIDASE D-AMINO ACID OXIDASE 2, ISOFORM A catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidase#PC00175 IXOSC|EnsemblGenome=LOC8035488|UniProtKB=A0ACM8E1M7 A0ACM8E1M7 LOC8035488 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051194|UniProtKB=A0ACM8DPE3 A0ACM8DPE3 LOC8051194 PTHR24056:SF581 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 8 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;protein kinase complex#GO:1902911 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121834622|UniProtKB=A0ACM8FP86 A0ACM8FP86 PTHR11958:SF63 SODIUM/DICARBOXYLATE SYMPORTER-RELATED AMINO ACID TRANSPORTER solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;acidic amino acid transmembrane transporter activity#GO:0015172;active transmembrane transporter activity#GO:0022804;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;amino acid transport#GO:0006865;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;carboxylic acid transport#GO:0046942;transport#GO:0006810;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 IXOSC|EnsemblGenome=LOC8039102|UniProtKB=A0ACM8DUJ6 A0ACM8DUJ6 LOC8039102 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8025719|UniProtKB=A0ACM8ERR6 A0ACM8ERR6 LOC8025719 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115315018|UniProtKB=A0ACM8F7W3 A0ACM8F7W3 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8052563|UniProtKB=A0ACM8FQM7 A0ACM8FQM7 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC121835941|UniProtKB=A0ACM8FWG4 A0ACM8FWG4 LOC121835941 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8050724|UniProtKB=A0ACM8DSJ2 A0ACM8DSJ2 LOC8050724 PTHR21689:SF2 LIN-9 PROTEIN LIN-9 HOMOLOG DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of cell cycle#GO:0051726;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115321688|UniProtKB=A0ACM8E1D8 A0ACM8E1D8 LOC115321688 PTHR13383:SF11 RIBONUCLEASE H2 SUBUNIT B RIBONUCLEASE H2 SUBUNIT B RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA catabolic process#GO:0006401;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 RNA metabolism protein#PC00031;endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC115325685|UniProtKB=A0ACM8FM23 A0ACM8FM23 Spf45 PTHR13288:SF9 SPLICING FACTOR 45 SPF45 SPLICING FACTOR 45 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8032339|UniProtKB=A0ACM8E493 A0ACM8E493 LOC8032339 PTHR24251:SF57 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8023543|UniProtKB=A0ACM8FD47 A0ACM8FD47 LOC8023543 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115332654|UniProtKB=A0ACM8EEF7 A0ACM8EEF7 LOC115332654 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC121837140|UniProtKB=A0ACM8G3E3 A0ACM8G3E3 LOC121837140 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC121046812|UniProtKB=A0ACM8FET0 A0ACM8FET0 LOC121046812 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115319279|UniProtKB=A0ACM8EK24 A0ACM8EK24 LOC115319279 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115330130|UniProtKB=A0ACM8EBA6 A0ACM8EBA6 LOC115330130 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115313047|UniProtKB=A0ACM8DSM8 A0ACM8DSM8 LOC115313047 PTHR33539:SF1 UPF0764 PROTEIN C16ORF89 UPF0764 PROTEIN C16ORF89 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8025877|UniProtKB=A0ACM8E0E4 A0ACM8E0E4 LOC8025877 PTHR11211:SF3 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN MOHAWK sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;muscle organ development#GO:0007517;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;muscle structure development#GO:0061061;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC121838005|UniProtKB=A0ACM8G669 A0ACM8G669 LOC121838005 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038016|UniProtKB=A0ACM8FUD0 A0ACM8FUD0 LOC8038016 PTHR19288:SF44 4-NITROPHENYLPHOSPHATASE-RELATED PHOSPHOLYSINE PHOSPHOHISTIDINE INORGANIC PYROPHOSPHATE PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120838738|UniProtKB=A0ACM8EJT2 A0ACM8EJT2 LOC120838738 PTHR10412:SF11 MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glucosidase#PC00108;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8027854|UniProtKB=A0ACM8FWU8 A0ACM8FWU8 LOC8027854 PTHR46526:SF1 CHORDIN CHORDIN binding#GO:0005488;protein binding#GO:0005515;cytokine binding#GO:0019955 regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of BMP signaling pathway#GO:0030510;negative regulation of BMP signaling pathway#GO:0030514;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;dorsal/ventral pattern formation#GO:0009953;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of cell communication#GO:0010648;anatomical structure development#GO:0048856;pattern specification process#GO:0007389;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 DPP signaling pathway#P06213>SOG#P06293;DPP-SCW signaling pathway#P06212>SOG#P06266;BMP/activin signaling pathway-drosophila#P06211>SOG#P06252;SCW signaling pathway#P06216>SOG#P06335 IXOSC|EnsemblGenome=LOC8043300|UniProtKB=A0ACM8E4G4 A0ACM8E4G4 LOC8043300 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC8034445|UniProtKB=A0ACM8E610 A0ACM8E610 LOC8034445 PTHR11736:SF14 MELANOMA-ASSOCIATED ANTIGEN MAGE ANTIGEN NSE3 HOMOLOG, SMC5-SMC6 COMPLEX COMPONENT nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115325897|UniProtKB=A0ACM8EXK3 A0ACM8EXK3 LOC115325897 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120838688|UniProtKB=A0ACM8EKF5 A0ACM8EKF5 LOC120838688 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC8032855|UniProtKB=A0ACM8DX95 A0ACM8DX95 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120845972|UniProtKB=A0ACM8F0G4 A0ACM8F0G4 LOC120845972 PTHR48014:SF32 SERINE/THREONINE-PROTEIN KINASE FRAY2 SERINE_THREONINE-PROTEIN KINASE FRAY2 kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein export from nucleus#GO:0006611;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179 protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121835777|UniProtKB=A0ACM8FVU2 A0ACM8FVU2 LOC121835777 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121834816|UniProtKB=A0ACM8FR52 A0ACM8FR52 LOC121834816 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023765|UniProtKB=A0ACM8DHI7 A0ACM8DHI7 LOC8023765 PTHR11309:SF99 FRIZZLED FRIZZLED-4 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 non-canonical Wnt signaling pathway#GO:0035567;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 IXOSC|EnsemblGenome=LOC120847486|UniProtKB=A0ACM8F3A8 A0ACM8F3A8 LOC120847486 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323280|UniProtKB=A0ACM8F1R6 A0ACM8F1R6 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329799|UniProtKB=A0ACM8ERB4 A0ACM8ERB4 LOC115329799 PTHR24253:SF153 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8051756|UniProtKB=A0ACM8DU61 A0ACM8DU61 PTHR10969:SF4 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN-LIKE 2 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular response to nutrient levels#GO:0031669;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC121837336|UniProtKB=A0ACM8G483 A0ACM8G483 LOC121837336 PTHR46925:SF2 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED G PROTEIN-COUPLED RECEPTOR TKR-1-RELATED signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121833952|UniProtKB=A0ACM8FNF0 A0ACM8FNF0 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024626|UniProtKB=A0ACM8DIG2 A0ACM8DIG2 LOC8024626 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8030062|UniProtKB=A0ACM8EE43 A0ACM8EE43 LOC8030062 PTHR10177:SF347 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase activator#PC00138 p53 pathway#P00059>Cyclin B#P04614;Cell cycle#P00013>Cyclin B#P00486 IXOSC|EnsemblGenome=LOC121834788|UniProtKB=A0ACM8FQX8 A0ACM8FQX8 LOC121834788 PTHR45913:SF5 EPM2A-INTERACTING PROTEIN 1 HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328850|UniProtKB=A0ACM8E8S8 A0ACM8E8S8 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115325263|UniProtKB=A0ACM8E4R5 A0ACM8E4R5 LOC115325263 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115333188|UniProtKB=A0ACM8ERW3 A0ACM8ERW3 LOC115333188 PTHR37162:SF13 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836105|UniProtKB=A0ACM8FYJ3 A0ACM8FYJ3 LOC121836105 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027982|UniProtKB=A0ACM8DJH7 A0ACM8DJH7 LOC8027982 PTHR24388:SF86 ZINC FINGER PROTEIN BTB DOMAIN-CONTAINING PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8036776|UniProtKB=A0ACM8DY54 A0ACM8DY54 LOC8036776 PTHR22948:SF29 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8028465|UniProtKB=A0ACM8E7Q6 A0ACM8E7Q6 LOC8028465 PTHR43829:SF33 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-9 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;carbohydrate transmembrane transporter activity#GO:0015144;channel activity#GO:0015267 cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219;transport#GO:0006810;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;water transport#GO:0006833;localization#GO:0051179;fluid transport#GO:0042044;organic hydroxy compound transport#GO:0015850 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 IXOSC|EnsemblGenome=LOC120836690|UniProtKB=A0ACM8EGJ2 A0ACM8EGJ2 LOC120836690 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8053334|UniProtKB=A0ACM8DL94 A0ACM8DL94 LOC8053334 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transporter#PC00227 IXOSC|EnsemblGenome=LOC8032672|UniProtKB=A0ACM8DW77 A0ACM8DW77 RpL35A PTHR10902:SF0 60S RIBOSOMAL PROTEIN L35A LARGE RIBOSOMAL SUBUNIT PROTEIN EL33 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC115331089|UniProtKB=A0ACM8ECM2 A0ACM8ECM2 LOC115331089 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC121047345|UniProtKB=A0ACM8FPR3 A0ACM8FPR3 LOC121047345 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121835029|UniProtKB=A0ACM8FR54 A0ACM8FR54 LOC121835029 PTHR43721:SF2 ELONGATION FACTOR TU-RELATED ELONGATION FACTOR TU, MITOCHONDRIAL translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC115315019|UniProtKB=A0ACM8FPG7 A0ACM8FPG7 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031524|UniProtKB=A0ACM8DIC4 A0ACM8DIC4 AlkB PTHR16557:SF12 ALKYLATED DNA REPAIR PROTEIN ALKB-RELATED NUCLEIC ACID DIOXYGENASE ALKBH1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;cation binding#GO:0043169;dioxygenase activity#GO:0051213;ferrous iron binding#GO:0008198;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;iron ion binding#GO:0005506;demethylase activity#GO:0032451;binding#GO:0005488;metal ion binding#GO:0046872 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115315581|UniProtKB=A0ACM8FVU6 A0ACM8FVU6 LOC115315581 PTHR18952:SF278 CARBONIC ANHYDRASE CARBONIC ANHYDRASE hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 IXOSC|EnsemblGenome=LOC8025440|UniProtKB=A0ACM8DZ05 A0ACM8DZ05 Plc21C PTHR10336:SF149 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE CLASSES I AND II phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;lipase activity#GO:0016298 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;calcium ion transmembrane transport#GO:0070588;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;signal transduction#GO:0007165;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;metabolic process#GO:0008152;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 lipase#PC00143;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Endothelin signaling pathway#P00019>PLCbeta#P00591;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Wnt signaling pathway#P00057>Phospholipase C#P01443;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 IXOSC|EnsemblGenome=LOC8023912|UniProtKB=A0ACM8DR39 A0ACM8DR39 LOC8023912 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843536|UniProtKB=A0ACM8EXF3 A0ACM8EXF3 LOC120843536 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8033925|UniProtKB=A0ACM8F5L0 A0ACM8F5L0 LOC8033925 PTHR43157:SF72 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 14-LIKE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8026296|UniProtKB=A0ACM8DHK6 A0ACM8DHK6 LOC8026296 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC120846342|UniProtKB=A0ACM8FSG1 A0ACM8FSG1 Pmp70 PTHR11384:SF62 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 3 ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monocarboxylic acid transmembrane transporter activity#GO:0008028;nucleotide binding#GO:0000166;carboxylic acid transmembrane transporter activity#GO:0046943;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;lipid catabolic process#GO:0016042;organelle organization#GO:0006996;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;fatty acid oxidation#GO:0019395;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;peroxisome organization#GO:0007031;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;transmembrane transport#GO:0055085;cellular localization#GO:0051641;carboxylic acid catabolic process#GO:0046395;macromolecule localization#GO:0033036;monocarboxylic acid catabolic process#GO:0072329;lipid transport#GO:0006869;lipid metabolic process#GO:0006629;transport#GO:0006810;fatty acid beta-oxidation#GO:0006635;intracellular transport#GO:0046907;fatty acid metabolic process#GO:0006631;establishment of localization#GO:0051234;lipid modification#GO:0030258;primary metabolic process#GO:0044238;carboxylic acid transmembrane transport#GO:1905039;catabolic process#GO:0009056;peroxisomal transport#GO:0043574;monocarboxylic acid transport#GO:0015718;lipid oxidation#GO:0034440;fatty acid transport#GO:0015908;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115319592|UniProtKB=A0ACM8EVM5 A0ACM8EVM5 LOC115319592 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027747|UniProtKB=A0ACM8E4B3 A0ACM8E4B3 Pif1 PTHR47642:SF9 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE PIF1 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8035113|UniProtKB=A0ACM8FIW5 A0ACM8FIW5 Rpt6 PTHR23073:SF12 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 8 macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 proteasome complex#GO:0000502;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC115325932|UniProtKB=A0ACM8FR00 A0ACM8FR00 LOC115325932 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8025512|UniProtKB=A0ACM8FRI3 A0ACM8FRI3 LOC8025512 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120842421|UniProtKB=A0ACM8ETR0 A0ACM8ETR0 LOC120842421 PTHR12372:SF8 PECANEX PROTEIN PECANEX endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC120844036|UniProtKB=A0ACM8EXM1 A0ACM8EXM1 LOC120844036 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331614|UniProtKB=A0ACM8FE67 A0ACM8FE67 LOC115331614 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121834092|UniProtKB=A0ACM8FP59 A0ACM8FP59 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115323227|UniProtKB=A0ACM8E2U8 A0ACM8E2U8 cic PTHR13059:SF13 HMG-BOX TRANSCRIPTION FACTOR BBX PROTEIN CAPICUA HOMOLOG DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121833065|UniProtKB=A0ACM8FJ45 A0ACM8FJ45 LOC121833065 PTHR13023:SF3 APYRASE SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1 nucleoside diphosphate phosphatase activity#GO:0017110;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462 proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;membrane#GO:0016020 hydrolase#PC00121;nucleotide phosphatase#PC00173 IXOSC|EnsemblGenome=LOC115312129|UniProtKB=A0ACM8DRY5 A0ACM8DRY5 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052079|UniProtKB=A0ACM8DZK2 A0ACM8DZK2 LOC8052079 PTHR24247:SF202 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 1 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 dendritic tree#GO:0097447;dendrite#GO:0030425;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 IXOSC|EnsemblGenome=LOC120839217|UniProtKB=A0ACM8ELQ7 A0ACM8ELQ7 LOC120839217 PTHR23055:SF198 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 1 molecular function regulator activity#GO:0098772;cyclase regulator activity#GO:0010851;enzyme activator activity#GO:0008047;cation binding#GO:0043169;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC121047105|UniProtKB=A0ACM8FFJ2 A0ACM8FFJ2 LOC121047105 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER FI24011P1-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115319555|UniProtKB=A0ACM8DZY2 A0ACM8DZY2 LOC115319555 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115316376|UniProtKB=A0ACM8F4L6 A0ACM8F4L6 LOC115316376 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8024160|UniProtKB=A0ACM8DHZ9 A0ACM8DHZ9 LOC8024160 PTHR45624:SF58 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ARGININE TRANSPORTER BAC1-LIKE transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;establishment of localization#GO:0051234;intracellular transport#GO:0046907;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC8027316|UniProtKB=A0ACM8DIX2 A0ACM8DIX2 LOC8027316 PTHR46350:SF2 RAS LIKE FAMILY 10 MEMBER B-RELATED RAS-LIKE PROTEIN FAMILY MEMBER 10B IXOSC|EnsemblGenome=LOC121834761|UniProtKB=A0ACM8FRX8 A0ACM8FRX8 LOC121834761 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115328470|UniProtKB=A0ACM8F6X9 A0ACM8F6X9 LOC115328470 PTHR22984:SF33 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115309048|UniProtKB=A0ACM8DND4 A0ACM8DND4 LOC115309048 PTHR44269:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED IP05441P alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121834777|UniProtKB=A0ACM8FQV6 A0ACM8FQV6 LOC121834777 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027192|UniProtKB=A0ACM8FHU9 A0ACM8FHU9 LOC8027192 PTHR19972:SF16 CALBINDIN CALBINDIN-32 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 dendrite#GO:0030425;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;axon#GO:0030424;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;neuron projection terminus#GO:0044306;cell junction#GO:0030054;axon terminus#GO:0043679;cytosol#GO:0005829;nucleus#GO:0005634;presynapse#GO:0098793;neuron projection#GO:0043005;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC121834538|UniProtKB=A0ACM8FQJ8 A0ACM8FQJ8 PTHR24300:SF445 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 18A1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;response to stimulus#GO:0050896;steroid metabolic process#GO:0008202;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115312857|UniProtKB=A0ACM8F9V1 A0ACM8F9V1 LOC115312857 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052107|UniProtKB=A0ACM8FKE4 A0ACM8FKE4 LOC8052107 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8027113|UniProtKB=A0ACM8EFW1 A0ACM8EFW1 Mcm2 PTHR11630:SF44 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM2 catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA replication initiation#GO:0006270;DNA damage response#GO:0006974;DNA recombination#GO:0006310;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;DNA metabolic process#GO:0006259;cell cycle DNA replication#GO:0044786;DNA repair#GO:0006281;metabolic process#GO:0008152;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;MCM complex#GO:0042555;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8051887|UniProtKB=A0ACM8E7J9 A0ACM8E7J9 LOC8051887 PTHR15574:SF21 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1 AND CUL4 ASSOCIATED FACTOR 8 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8032969|UniProtKB=A0ACM8DMZ0 A0ACM8DMZ0 LOC8032969 PTHR21180:SF33 ENDONUCLEASE/EXONUCLEASE/PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1 ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE FAMILY DOMAIN-CONTAINING PROTEIN 1 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8036510|UniProtKB=A0ACM8DK14 A0ACM8DK14 LOC8036510 PTHR31638:SF3 DAZ-ASSOCIATED PROTEIN 2 DAZ-ASSOCIATED PROTEIN 2 IXOSC|EnsemblGenome=LOC8035410|UniProtKB=A0ACM8G8B6 A0ACM8G8B6 LOC8035410 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115323814|UniProtKB=A0ACM8EN89 A0ACM8EN89 LOC115323814 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031182|UniProtKB=A0ACM8F0Y0 A0ACM8F0Y0 LOC8031182 PTHR46560:SF3 CYPHER, ISOFORM B ZP DOMAIN-CONTAINING PROTEIN anatomical structure development#GO:0048856;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC120836263|UniProtKB=A0ACM8EYT4 A0ACM8EYT4 LOC120836263 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313525|UniProtKB=A0ACM8FHP7 A0ACM8FHP7 CYLD PTHR11830:SF3 40S RIBOSOMAL PROTEIN S3A UBIQUITINYL HYDROLASE 1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;structural molecule activity#GO:0005198;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;structural constituent of ribosome#GO:0003735;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8043621|UniProtKB=A0ACM8DVB1 A0ACM8DVB1 LOC8043621 PTHR15913:SF0 ACID CLUSTER PROTEIN 33 MASPARDIN IXOSC|EnsemblGenome=LOC115324524|UniProtKB=A0ACM8E409 A0ACM8E409 LOC115324524 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8029399|UniProtKB=A0ACM8FAB2 A0ACM8FAB2 LOC8029399 PTHR44154:SF1 QUINONE OXIDOREDUCTASE ZETA-CRYSTALLIN mRNA 3'-UTR binding#GO:0003730;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;oxidoreductase activity, acting on NAD(P)H#GO:0016651;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;mRNA binding#GO:0003729;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Huntington disease#P00029>PIG3#G01535 IXOSC|EnsemblGenome=LOC120840192|UniProtKB=A0ACM8ENC4 A0ACM8ENC4 LOC120840192 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8034521|UniProtKB=A0ACM8G4A0 A0ACM8G4A0 LOC8034521 PTHR24012:SF877 RNA BINDING PROTEIN BRUNO 1, ISOFORM B-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8053221|UniProtKB=A0ACM8E097 A0ACM8E097 LOC8053221 PTHR11407:SF76 LYSOZYME C LYSOZYME hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115318090|UniProtKB=A0ACM8DXS4 A0ACM8DXS4 LOC115318090 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC120840432|UniProtKB=A0ACM8EP06 A0ACM8EP06 LOC120840432 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8027808|UniProtKB=A0ACM8FKH6 A0ACM8FKH6 LOC8027808 PTHR12231:SF283 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8025700|UniProtKB=A0ACM8DX24 A0ACM8DX24 LOC8025700 PTHR13486:SF2 TELOMERE LENGTH AND SILENCING PROTEIN 1 TLS1 FAMILY MEMBER SPLICING FACTOR C9ORF78 mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120836147|UniProtKB=A0ACM8ET76 A0ACM8ET76 LOC120836147 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120842746|UniProtKB=A0ACM8EUD5 A0ACM8EUD5 LOC120842746 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8023426|UniProtKB=A0ACM8EC93 A0ACM8EC93 LOC8023426 PTHR47507:SF6 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8036309|UniProtKB=A0ACM8EJ86 A0ACM8EJ86 PTHR10554:SF12 SYNTROPHIN IP02644P plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8042927|UniProtKB=A0ACM8EHV1 A0ACM8EHV1 LOC8042927 PTHR43826:SF3 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;organophosphate ester transport#GO:0015748;phosphate ion transport#GO:0006817 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115322514|UniProtKB=A0ACM8F7W2 A0ACM8F7W2 LOC115322514 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115308180|UniProtKB=A0ACM8E5Y1 A0ACM8E5Y1 LOC115308180 PTHR23050:SF549 CALCIUM BINDING PROTEIN AT22559P ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;centriole replication#GO:0007099 intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 calcium-binding protein#PC00060;calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8033691|UniProtKB=A0ACM8DV15 A0ACM8DV15 mmy PTHR11952:SF20 UDP- GLUCOSE PYROPHOSPHORYLASE UDP-N-ACETYLGLUCOSAMINE DIPHOSPHORYLASE nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 UDP-N-acetylglucosamine biosynthetic process#GO:0006048;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC115311742|UniProtKB=A0ACM8FTR8 A0ACM8FTR8 bent PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8038725|UniProtKB=A0ACM8DYF9 A0ACM8DYF9 LOC8038725 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8023161|UniProtKB=A0ACM8DGG7 A0ACM8DGG7 LOC8023161 PTHR46568:SF1 ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE, PEROXISOMAL transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777 IXOSC|EnsemblGenome=LOC121838344|UniProtKB=A0ACM8G8U5 A0ACM8G8U5 LOC121838344 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC120837496|UniProtKB=A0ACM8EHI2 A0ACM8EHI2 LOC120837496 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8035568|UniProtKB=A0ACM8DR90 A0ACM8DR90 LOC8035568 PTHR23345:SF15 VITELLOGENIN-RELATED VITELLOGENIN-6 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 storage protein#PC00210 IXOSC|EnsemblGenome=LOC8052708|UniProtKB=A0ACM8DGK6 A0ACM8DGK6 eIF3h PTHR10410:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT H deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;translation factor activity#GO:0180051;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;translation initiation factor activity#GO:0003743;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribonucleoprotein complex#GO:1990904;eukaryotic translation initiation factor 3 complex#GO:0005852;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation factor#PC00223;translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120840260|UniProtKB=A0ACM8FKV3 A0ACM8FKV3 LOC120840260 PTHR21581:SF34 D-ALANYL-D-ALANINE CARBOXYPEPTIDASE TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 12 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8031689|UniProtKB=A0ACM8FAK3 A0ACM8FAK3 LOC8031689 PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;C4-dicarboxylate transmembrane transporter activity#GO:0015556;citrate transmembrane transporter activity#GO:0015137;succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310 citrate transport#GO:0015746;tricarboxylic acid transport#GO:0006842;transport#GO:0006810;carboxylic acid transport#GO:0046942;C4-dicarboxylate transport#GO:0015740;organic acid transport#GO:0015849;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;succinate transport#GO:0015744;dicarboxylic acid transport#GO:0006835 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC120841306|UniProtKB=A0ACM8FF74 A0ACM8FF74 LOC120841306 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8038847|UniProtKB=A0ACM8F926 A0ACM8F926 LOC8038847 PTHR45716:SF2 BITESIZE, ISOFORM I BITESIZE, ISOFORM I signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115332476|UniProtKB=A0ACM8F854 A0ACM8F854 LOC115332476 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8053927|UniProtKB=A0ACM8DL89 A0ACM8DL89 Taf7 PTHR12228:SF0 TRANSCRIPTION INITIATION FACTOR TFIID 55 KD SUBUNIT-RELATED TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 7 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 IXOSC|EnsemblGenome=LOC8024203|UniProtKB=A0ACM8DZH6 A0ACM8DZH6 LOC8024203 PTHR14269:SF4 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED CAT EYE SYNDROME CRITICAL REGION PROTEIN 5 phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034506|UniProtKB=A0ACM8DT02 A0ACM8DT02 LOC8034506 PTHR11861:SF8 MELANOCYTE PROTEIN PMEL 17-RELATED PKD DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 IXOSC|EnsemblGenome=LOC121836681|UniProtKB=A0ACM8G0J3 A0ACM8G0J3 LOC121836681 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120842883|UniProtKB=A0ACM8EUR8 A0ACM8EUR8 LOC120842883 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030766|UniProtKB=A0ACM8EXJ4 A0ACM8EXJ4 LOC8030766 PTHR10797:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT POLY(A)-SPECIFIC RIBONUCLEASE hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788 positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8035600|UniProtKB=A0ACM8DJU5 A0ACM8DJU5 FRG1 PTHR12928:SF0 FRG1 PROTEIN PROTEIN FRG1 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;catalytic step 2 spliceosome#GO:0071013;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8025781|UniProtKB=A0ACM8DQF2 A0ACM8DQF2 LOC8025781 PTHR22938:SF0 ZINC FINGER PROTEIN 598 E3 UBIQUITIN-PROTEIN LIGASE ZNF598 ribonucleoprotein complex binding#GO:0043021;ubiquitin-like protein ligase activity#GO:0061659;protein-containing complex binding#GO:0044877;ubiquitin-protein transferase activity#GO:0004842;ribosome binding#GO:0043022;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;translational elongation#GO:0006414;gene expression#GO:0010467;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component disassembly#GO:0022411;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;protein modification by small protein conjugation or removal#GO:0070647;translation#GO:0006412;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular component organization#GO:0016043;rescue of stalled cytosolic ribosome#GO:0072344;protein modification by small protein conjugation#GO:0032446 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8035451|UniProtKB=A0ACM8E3A8 A0ACM8E3A8 LOC8035451 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8038634|UniProtKB=A0ACM8DZH8 A0ACM8DZH8 LOC8038634 PTHR38537:SF17 JITTERBUG, ISOFORM N FILAMIN-A IXOSC|EnsemblGenome=LOC120845218|UniProtKB=A0ACM8F0C4 A0ACM8F0C4 LOC120845218 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115329811|UniProtKB=A0ACM8F9U5 A0ACM8F9U5 LOC115329811 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC121835652|UniProtKB=A0ACM8FUJ4 A0ACM8FUJ4 LOC121835652 PTHR46289:SF24 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE IXOSC|EnsemblGenome=LOC121835746|UniProtKB=A0ACM8FWE8 A0ACM8FWE8 LOC121835746 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120849114|UniProtKB=A0ACM8F819 A0ACM8F819 LOC120849114 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8040524|UniProtKB=A0ACM8E9Q6 A0ACM8E9Q6 HDAC3 PTHR10625:SF36 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 3 catalytic activity#GO:0003824;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;catalytic activity, acting on a protein#GO:0140096 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Wnt signaling pathway#P00057>Histone deacetylase#P01472 IXOSC|EnsemblGenome=LOC115324714|UniProtKB=A0ACM8E539 A0ACM8E539 LOC115324714 PTHR21561:SF12 INO80 COMPLEX SUBUNIT B INO80 COMPLEX SUBUNIT B SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC120836889|UniProtKB=A0ACM8G069 A0ACM8G069 LOC120836889 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120844029|UniProtKB=A0ACM8EXL9 A0ACM8EXL9 LOC120844029 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844727|UniProtKB=A0ACM8EZ30 A0ACM8EZ30 LOC120844727 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120841286|UniProtKB=A0ACM8ESD0 A0ACM8ESD0 LOC120841286 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120846132|UniProtKB=A0ACM8FKL3 A0ACM8FKL3 LOC120846132 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8029553|UniProtKB=A0ACM8DWC6 A0ACM8DWC6 LOC8029553 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC121837133|UniProtKB=A0ACM8G207 A0ACM8G207 LOC121837133 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8032025|UniProtKB=A0ACM8ERL3 A0ACM8ERL3 LOC8032025 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120842420|UniProtKB=A0ACM8G3U6 A0ACM8G3U6 LOC120842420 PTHR10177:SF527 CYCLINS CYCLIN D, ISOFORM D kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911 kinase activator#PC00138 Cell cycle#P00013>Cyclin D#P00484;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 IXOSC|EnsemblGenome=LOC115317448|UniProtKB=A0ACM8DX60 A0ACM8DX60 LOC115317448 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8023389|UniProtKB=A0ACM8EAE6 A0ACM8EAE6 LOC8023389 PTHR15989:SF5 VEZATIN VEZATIN cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120836335|UniProtKB=A0ACM8F6B0 A0ACM8F6B0 LOC120836335 PTHR10125:SF31 P2X PURINOCEPTOR P2X RECEPTOR E monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;calcium ion transmembrane transport#GO:0070588;cellular process#GO:0009987;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC120840811|UniProtKB=A0ACM8G960 A0ACM8G960 LOC120840811 PTHR46609:SF6 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN EXONUCLEASE, PHAGE-TYPE_RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8053356|UniProtKB=A0ACM8DPV8 A0ACM8DPV8 LOC8053356 PTHR11932:SF177 CULLIN CULLIN-4A structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;response to stress#GO:0006950;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;DNA damage response#GO:0006974;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8024736|UniProtKB=A0ACM8EW70 A0ACM8EW70 LOC8024736 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121834764|UniProtKB=A0ACM8FQZ5 A0ACM8FQZ5 LOC121834764 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8042579|UniProtKB=A0ACM8G2D9 A0ACM8G2D9 LOC8042579 PTHR23113:SF224 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cell projection organization#GO:0031344;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of neuron projection development#GO:0010975;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;positive regulation of neuron projection development#GO:0010976;Ras protein signal transduction#GO:0007265;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 Integrin signalling pathway#P00034>C3G#P00929 IXOSC|EnsemblGenome=LOC8031772|UniProtKB=A0ACM8FSR9 A0ACM8FSR9 LOC8031772 PTHR12027:SF97 WNT RELATED PROTEIN WNT protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell fate commitment#GO:0045165;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC115308658|UniProtKB=A0ACM8G8R9 A0ACM8G8R9 LOC115308658 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051654|UniProtKB=A0ACM8DLB8 A0ACM8DLB8 LOC8051654 PTHR11850:SF59 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN TGIF1 DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC121836783|UniProtKB=A0ACM8G1U7 A0ACM8G1U7 LOC121836783 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037312|UniProtKB=A0ACM8DK34 A0ACM8DK34 LOC8037312 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC120844138|UniProtKB=A0ACM8EXX6 A0ACM8EXX6 LOC120844138 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025722|UniProtKB=A0ACM8DJH2 A0ACM8DJH2 ND-B17.2 PTHR12910:SF2 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B17.2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 12 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115332903|UniProtKB=A0ACM8FVG4 A0ACM8FVG4 LOC115332903 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887 cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;transferase complex#GO:1990234 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC121834863|UniProtKB=A0ACM8FQM6 A0ACM8FQM6 LOC121834863 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120836368|UniProtKB=A0ACM8EEW8 A0ACM8EEW8 LOC120836368 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8028748|UniProtKB=A0ACM8DN32 A0ACM8DN32 EDTP PTHR13524:SF2 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE MTMR14 phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121835691|UniProtKB=A0ACM8FWJ3 A0ACM8FWJ3 LOC121835691 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8037713|UniProtKB=A0ACM8EEL9 A0ACM8EEL9 Tapdelta PTHR12731:SF1 TRANSLOCON-ASSOCIATED PROTEIN, DELTA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT DELTA cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC121833088|UniProtKB=A0ACM8FJ69 A0ACM8FJ69 LOC8026193 PTHR11849:SF201 ETS ETS DNA-BINDING PROTEIN POKKURI DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8028800|UniProtKB=A0ACM8DW04 A0ACM8DW04 LOC8028800 PTHR21522:SF58 PROTON CHANNEL OTOP OTOPETRIN proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8043922|UniProtKB=A0ACM8F8N7 A0ACM8F8N7 LOC8043922 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120841231|UniProtKB=A0ACM8EQU1 A0ACM8EQU1 LOC120841231 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120842037|UniProtKB=A0ACM8ESX8 A0ACM8ESX8 LOC120842037 PTHR45823:SF1 T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN SAP DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030118|UniProtKB=A0ACM8DJA8 A0ACM8DJA8 LOC8030118 PTHR45902:SF7 LATROPHILIN RECEPTOR-LIKE PROTEIN A G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8028805|UniProtKB=A0ACM8DH84 A0ACM8DH84 LOC8028805 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115320012|UniProtKB=A0ACM8E0J1 A0ACM8E0J1 LOC115320012 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120838940|UniProtKB=A0ACM8EKX0 A0ACM8EKX0 LOC120838940 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043155|UniProtKB=A0ACM8ECR4 A0ACM8ECR4 PTHR11963:SF4 LEUCINE AMINOPEPTIDASE-RELATED AMINOPEPTIDASE NPEPL1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120850131|UniProtKB=A0ACM8F9H2 A0ACM8F9H2 LOC120850131 PTHR43563:SF26 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056;phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;amine metabolic process#GO:0009308;serotonin metabolic process#GO:0042428;amine catabolic process#GO:0009310;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxidase#PC00175 Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 IXOSC|EnsemblGenome=LOC8032754|UniProtKB=A0ACM8DGQ9 A0ACM8DGQ9 LOC8032754 PTHR10858:SF23 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE II nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;execution phase of apoptosis#GO:0097194;cell death#GO:0008219;apoptotic process#GO:0006915;cellular component organization#GO:0016043;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC8023782|UniProtKB=A0ACM8E1J1 A0ACM8E1J1 pkaap PTHR13155:SF1 A-KINASE ANCHOR PROTEINS A-KINASE ANCHOR PROTEIN 10, MITOCHONDRIAL protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule localization#GO:0033036;localization#GO:0051179;intracellular protein localization#GO:0008104 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115327221|UniProtKB=A0ACM8G7C5 A0ACM8G7C5 LOC115327221 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120843976|UniProtKB=A0ACM8FLW2 A0ACM8FLW2 LOC120843976 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035055|UniProtKB=A0ACM8DJP6 A0ACM8DJP6 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115329222|UniProtKB=A0ACM8EAN8 A0ACM8EAN8 LOC115329222 PTHR13172:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM10 B protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 mitochondrial intermembrane space#GO:0005758;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;mitochondrion#GO:0005739 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121837813|UniProtKB=A0ACM8G585 A0ACM8G585 LOC121837813 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120842792|UniProtKB=A0ACM8EUL5 A0ACM8EUL5 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115310055|UniProtKB=A0ACM8EZJ6 A0ACM8EZJ6 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8051793|UniProtKB=A0ACM8E460 A0ACM8E460 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8031704|UniProtKB=A0ACM8E866 A0ACM8E866 LOC8031704 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8023099|UniProtKB=A0ACM8EBK2 A0ACM8EBK2 LOC8023099 PTHR36693:SF1 GH02722P GH02722P IXOSC|EnsemblGenome=LOC115326538|UniProtKB=A0ACM8EVK2 A0ACM8EVK2 LOC115326538 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8024859|UniProtKB=A0ACM8E6Z4 A0ACM8E6Z4 LOC8024859 PTHR11561:SF0 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP] metal ion binding#GO:0046872;lyase activity#GO:0016829;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 response to nutrient levels#GO:0031667;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;response to glucose#GO:0009749;small molecule biosynthetic process#GO:0044283;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;cellular response to stimulus#GO:0051716;hexose biosynthetic process#GO:0019319;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;response to starvation#GO:0042594;carbohydrate metabolic process#GO:0005975;homeostatic process#GO:0042592;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;gluconeogenesis#GO:0006094;alcohol biosynthetic process#GO:0046165;response to stress#GO:0006950;carbohydrate biosynthetic process#GO:0016051;response to lipid#GO:0033993;response to chemical#GO:0042221;chemical homeostasis#GO:0048878;alcohol metabolic process#GO:0006066;monosaccharide metabolic process#GO:0005996;cellular response to glucose stimulus#GO:0071333;metabolic process#GO:0008152;glucose homeostasis#GO:0042593;glucose metabolic process#GO:0006006;carbohydrate homeostasis#GO:0033500;carboxylic acid metabolic process#GO:0019752;response to hexose#GO:0009746;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to monosaccharide#GO:0034284;intracellular glucose homeostasis#GO:0001678;response to carbohydrate#GO:0009743 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Phosphoenolpyruvate Carboxykinase#P03135 IXOSC|EnsemblGenome=LOC8032502|UniProtKB=A0ACM8DJJ2 A0ACM8DJJ2 LOC8032502 PTHR12128:SF21 DIHYDRODIPICOLINATE SYNTHASE N-ACETYLNEURAMINATE LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 lyase#PC00144 N-acetylglucosamine metabolism#P02756>N-acetylneuraminate lyase#P03040 IXOSC|EnsemblGenome=LOC8030703|UniProtKB=A0ACM8DUR5 A0ACM8DUR5 LOC8030703 PTHR12049:SF7 PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL PROTEIN ARGININE METHYLTRANSFERASE NDUFAF7, MITOCHONDRIAL N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC8039795|UniProtKB=A0ACM8FT22 A0ACM8FT22 LOC8039795 PTHR15348:SF0 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN ARID DOMAIN- CONTAINING PROTEIN DEAD RINGER PROTEIN B-CELL REGULATOR OF IGH TRANSCRIPTION BRIGHT PROTEIN DEAD RINGER nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC121046905|UniProtKB=A0ACM8FG44 A0ACM8FG44 LOC121046905 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8033653|UniProtKB=A0ACM8EAI6 A0ACM8EAI6 LOC8033653 PTHR11588:SF524 TUBULIN TUBULIN BETA CHAIN guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226 cytoskeletal protein#PC00085;tubulin#PC00228 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 IXOSC|EnsemblGenome=LOC8025468|UniProtKB=A0ACM8G2L6 A0ACM8G2L6 LOC8025468 PTHR14247:SF8 BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 3 HOMOLOG-LIKE PROTEIN SH2 DOMAIN-CONTAINING PROTEIN 3C-RELATED IXOSC|EnsemblGenome=LOC8038273|UniProtKB=A0ACM8E3Q5 A0ACM8E3Q5 gdl PTHR13054:SF2 DIGEORGE SYNDROME CRITICAL REGION 6 DGCR6 FAMILY MEMBER PROTEIN DGCR6 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121833043|UniProtKB=A0ACM8FK52 A0ACM8FK52 LOC121833043 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8043650|UniProtKB=A0ACM8DW70 A0ACM8DW70 LOC8043650 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8044145|UniProtKB=A0ACM8G8Z5 A0ACM8G8Z5 LOC8044145 PTHR12424:SF8 TWEETY-RELATED PROTEIN TWEETY HOMOLOG 1 ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8039540|UniProtKB=A0ACM8DPR5 A0ACM8DPR5 LOC8039540 PTHR15414:SF5 OS-9-RELATED PROTEIN OS-9 proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;cellular localization#GO:0051641;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;localization#GO:0051179;cell communication#GO:0007154;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8041774|UniProtKB=A0ACM8DKS2 A0ACM8DKS2 LOC8041774 PTHR31449:SF3 UPF0598 PROTEIN C8ORF82 UPF0598 PROTEIN C8ORF82 IXOSC|EnsemblGenome=LOC121833971|UniProtKB=A0ACM8FNI1 A0ACM8FNI1 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053560|UniProtKB=A0ACM8DLA3 A0ACM8DLA3 Mpc1 PTHR14154:SF3 UPF0041 BRAIN PROTEIN 44-RELATED MITOCHONDRIAL PYRUVATE CARRIER carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monocarboxylic acid transport#GO:0015718;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;carboxylic acid transport#GO:0046942;mitochondrial transmembrane transport#GO:1990542;organic acid transport#GO:0015849;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120845831|UniProtKB=A0ACM8F0W3 A0ACM8F0W3 PTHR43038:SF3 ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 ABC TRANSPORTER G FAMILY MEMBER 23 ISOFORM X1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115332520|UniProtKB=A0ACM8EYZ8 A0ACM8EYZ8 LOC115332520 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115315179|UniProtKB=A0ACM8G6R6 A0ACM8G6R6 LOC115315179 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8032289|UniProtKB=A0ACM8DR75 A0ACM8DR75 LOC8032289 PTHR24412:SF451 KELCH PROTEIN FI11917P enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027797|UniProtKB=A0ACM8FMC8 A0ACM8FMC8 LOC8027797 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120848502|UniProtKB=A0ACM8FKE8 A0ACM8FKE8 LOC120848502 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC120843200|UniProtKB=A0ACM8EVD2 A0ACM8EVD2 LOC120843200 PTHR24366:SF140 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS KEKKON 1, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115330796|UniProtKB=A0ACM8G950 A0ACM8G950 LOC115330796 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310122|UniProtKB=A0ACM8F375 A0ACM8F375 LOC115310122 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115332569|UniProtKB=A0ACM8EJY2 A0ACM8EJY2 LOC115332569 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320911|UniProtKB=A0ACM8E0P2 A0ACM8E0P2 LOC115320911 PTHR48094:SF18 PROTEIN/NUCLEIC ACID DEGLYCASE DJ-1-RELATED GLUTAMINE AMIDOTRANSFERASE-LIKE CLASS 1 DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC120850325|UniProtKB=A0ACM8FAL5 A0ACM8FAL5 LOC120850325 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8042553|UniProtKB=A0ACM8EAL3 A0ACM8EAL3 LOC8042553 PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8026447|UniProtKB=A0ACM8E7B4 A0ACM8E7B4 Fibp PTHR13223:SF3 ACIDIC FIBROBLAST GROWTH FACTOR INTRACELLULAR BINDING PROTEIN AFGF INTRACELLULAR BINDING PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115328574|UniProtKB=A0ACM8FRB5 A0ACM8FRB5 LOC115328574 PTHR45833:SF1 METHIONINE SYNTHASE METHIONINE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 tetrahydrofolate metabolic process#GO:0046653;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;carboxylic acid biosynthetic process#GO:0046394;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 S-adenosylmethionine biosynthesis#P02773>Cobalamin-dependent homocysteine transmethylase#P03142;Formyltetrahydrofolate biosynthesis#P02743>Cobalamin dependent homocysteine transmethylase#P02953;Methionine biosynthesis#P02753>Homocysteine transmethylase#P03024 IXOSC|EnsemblGenome=LOC8029024|UniProtKB=A0ACM8DHH4 A0ACM8DHH4 LOC8029024 PTHR10026:SF51 CYCLIN CYCLIN-T kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription elongation#GO:0032784;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 kinase activator#PC00138;kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC121833232|UniProtKB=A0ACM8FK26 A0ACM8FK26 LOC121833232 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8041899|UniProtKB=A0ACM8FJ74 A0ACM8FJ74 LOC8041899 PTHR11814:SF282 SULFATE TRANSPORTER SODIUM-INDEPENDENT SULFATE ANION TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115327317|UniProtKB=A0ACM8F4C8 A0ACM8F4C8 LOC115327317 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039489|UniProtKB=A0ACM8FVE9 A0ACM8FVE9 LOC8039489 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8038921|UniProtKB=A0ACM8E2V9 A0ACM8E2V9 LOC8038921 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8051014|UniProtKB=A0ACM8FW02 A0ACM8FW02 LOC8051014 PTHR24092:SF148 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE ATPase-coupled intramembrane lipid carrier activity#GO:0140326;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8027004|UniProtKB=A0ACM8EXV7 A0ACM8EXV7 LOC8027004 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8023854|UniProtKB=A0ACM8EEW6 A0ACM8EEW6 Smyd5 PTHR46402:SF2 SET AND MYND DOMAIN-CONTAINING PROTEIN 5 PROTEIN-LYSINE N-TRIMETHYLTRANSFERASE SMYD5 N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043 IXOSC|EnsemblGenome=LOC8052701|UniProtKB=A0ACM8DWY5 A0ACM8DWY5 Ada2a PTHR12374:SF85 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-ALPHA chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115311518|UniProtKB=A0ACM8ERZ3 A0ACM8ERZ3 LOC115311518 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115314049|UniProtKB=A0ACM8ETN6 A0ACM8ETN6 LOC115314049 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030299|UniProtKB=A0ACM8FEK2 A0ACM8FEK2 acj6 PTHR11636:SF70 POU DOMAIN INHIBITORY POU PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC121048156|UniProtKB=A0ACM8FHU2 A0ACM8FHU2 LOC121048156 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115332093|UniProtKB=A0ACM8FPD1 A0ACM8FPD1 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040144|UniProtKB=A0ACM8G097 A0ACM8G097 LOC8040144 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8023759|UniProtKB=A0ACM8E363 A0ACM8E363 Reps PTHR11216:SF174 EH DOMAIN GH06923P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8052468|UniProtKB=A0ACM8EFC7 A0ACM8EFC7 LOC8052468 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850718|UniProtKB=A0ACM8FAP9 A0ACM8FAP9 LOC120850718 PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121837915|UniProtKB=A0ACM8G6P3 A0ACM8G6P3 LOC121837915 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8024912|UniProtKB=A0ACM8E9R1 A0ACM8E9R1 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC121833066|UniProtKB=A0ACM8FJD9 A0ACM8FJD9 LOC121833066 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115325354|UniProtKB=A0ACM8FA21 A0ACM8FA21 LOC115325354 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8039621|UniProtKB=A0ACM8DRY4 A0ACM8DRY4 LOC8039621 PTHR13009:SF22 HEAT SHOCK PROTEIN 90 HSP90 CO-CHAPERONE AHA-1 ACTIVATOR OF 90 KDA HEAT SHOCK PROTEIN ATPASE HOMOLOG 1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120840328|UniProtKB=A0ACM8FL92 A0ACM8FL92 LOC120840328 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC121835384|UniProtKB=A0ACM8FUW4 A0ACM8FUW4 LOC121835384 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8036094|UniProtKB=A0ACM8EC24 A0ACM8EC24 LOC8036094 PTHR16160:SF13 FERMITIN 2-RELATED FERMITIN 2-RELATED cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515 cell-substrate adhesion#GO:0031589;cellular process#GO:0009987;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;cell-substrate junction#GO:0030055 IXOSC|EnsemblGenome=LOC8026588|UniProtKB=A0ACM8DSS1 A0ACM8DSS1 LOC8026588 PTHR37402:SF1 GRAM DOMAIN-CONTAINING PROTEIN 4 GRAM DOMAIN-CONTAINING PROTEIN 4 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of immune system process#GO:0002682;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of innate immune response#GO:0045088;positive regulation of apoptotic process#GO:0043065;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of immune system process#GO:0002683;negative regulation of signal transduction#GO:0009968;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8043904|UniProtKB=A0ACM8EYM8 A0ACM8EYM8 LOC8043904 PTHR11610:SF204 LIPASE PHOSPHOLIPASE A1 1-LIKE PROTEIN lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115308400|UniProtKB=A0ACM8DMD8 A0ACM8DMD8 LOC115308400 PTHR23427:SF15 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 1 mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8038907|UniProtKB=A0ACM8DKA1 A0ACM8DKA1 LOC8038907 PTHR13172:SF5 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9 protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 mitochondrial intermembrane space#GO:0005758;membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115321516|UniProtKB=A0ACM8E1Z9 A0ACM8E1Z9 LOC115321516 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835550|UniProtKB=A0ACM8FVX9 A0ACM8FVX9 LOC121835550 PTHR24028:SF342 CADHERIN-87A PROTOCADHERIN FAT 4 cellular process#GO:0009987;cell adhesion#GO:0007155 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cadherin#PC00057;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8033762|UniProtKB=A0ACM8G110 A0ACM8G110 LOC8033762 PTHR15904:SF17 FAM13 RHO-GAP DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844864|UniProtKB=A0ACM8FHS8 A0ACM8FHS8 LOC120844864 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220 IXOSC|EnsemblGenome=LOC115311191|UniProtKB=A0ACM8DQI7 A0ACM8DQI7 omd PTHR31697:SF2 INTEGRATOR COMPLEX SUBUNIT 5 INTEGRATOR COMPLEX SUBUNIT 5 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121046660|UniProtKB=A0ACM8FII7 A0ACM8FII7 LOC121046660 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8025089|UniProtKB=A0ACM8G090 A0ACM8G090 CPSF1 PTHR10644:SF26 DNA REPAIR/RNA PROCESSING CPSF FAMILY CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 1 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8026381|UniProtKB=A0ACM8DZS7 A0ACM8DZS7 PTHR11028:SF6 VACUOLAR ATP SYNTHASE SUBUNIT AC39 V-TYPE PROTON ATPASE SUBUNIT D 1 ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075 regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;localization#GO:0051179;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;vacuolar acidification#GO:0007035;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007 endomembrane system#GO:0012505;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;proton-transporting two-sector ATPase complex#GO:0016469;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;early endosome#GO:0005769;ATPase dependent transmembrane transport complex#GO:0098533;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;endosome#GO:0005768 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC121833278|UniProtKB=A0ACM8FIU3 A0ACM8FIU3 LOC121833278 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC121045728|UniProtKB=A0ACM8FXW0 A0ACM8FXW0 LOC121045728 PTHR45823:SF1 T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN SAP DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033116|UniProtKB=A0ACM8G4E6 A0ACM8G4E6 XRCC1 PTHR11370:SF6 DNA-REPAIR PROTEIN XRCC1 DNA REPAIR PROTEIN XRCC1 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8054037|UniProtKB=A0ACM8FJJ9 A0ACM8FJJ9 LOC8054037 PTHR10333:SF114 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 3 protein-macromolecule adaptor activity#GO:0030674;histone H3 reader activity#GO:0140006;molecular adaptor activity#GO:0060090;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromatin#GO:0000785;nucleus#GO:0005634;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115323448|UniProtKB=A0ACM8E490 A0ACM8E490 LOC115323448 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051224|UniProtKB=A0ACM8DW42 A0ACM8DW42 PTHR24416:SF550 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1-RELATED protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of cell population proliferation#GO:0008284;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;fibroblast growth factor receptor signaling pathway#GO:0008543;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8036277|UniProtKB=A0ACM8FC56 A0ACM8FC56 PTHR12616:SF8 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 8 HOMOLOG protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;vesicle organization#GO:0016050;transport#GO:0006810;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987 late endosome#GO:0005770;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8031960|UniProtKB=A0ACM8E7Z3 A0ACM8E7Z3 LOC8031960 PTHR14454:SF11 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER SERRANO, ISOFORM F IXOSC|EnsemblGenome=LOC8036929|UniProtKB=A0ACM8DZM1 A0ACM8DZM1 Usp5 PTHR21646:SF10 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8030626|UniProtKB=A0ACM8DHB5 A0ACM8DHB5 mRpS18A PTHR13479:SF66 30S RIBOSOMAL PROTEIN S18 LARGE RIBOSOMAL SUBUNIT PROTEIN ML66 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial large ribosomal subunit#GO:0005762;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8043147|UniProtKB=A0ACM8E324 A0ACM8E324 LOC8043147 PTHR22970:SF14 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115314307|UniProtKB=A0ACM8F132 A0ACM8F132 LOC115314307 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121835875|UniProtKB=A0ACM8FW68 A0ACM8FW68 LOC121835875 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042666|UniProtKB=A0ACM8DW60 A0ACM8DW60 Fancl PTHR13206:SF0 UBIQUITIN LIGASE PROTEIN PHF9 FANCONI ANEMIA GROUP L PROTEIN E3 UBIQUITIN-PROTEIN LIGASE FANCL ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8023770|UniProtKB=A0ACM8DPR1 A0ACM8DPR1 LOC8023770 PTHR24155:SF10 OSTEOCLAST-STIMULATING FACTOR 1 OSTEOCLAST-STIMULATING FACTOR 1 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 IXOSC|EnsemblGenome=LOC8042812|UniProtKB=A0ACM8DKX1 A0ACM8DKX1 LOC8042812 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120842757|UniProtKB=A0ACM8EVL4 A0ACM8EVL4 LOC120843253 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035399|UniProtKB=A0ACM8FGY7 A0ACM8FGY7 LOC8035399 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC115332661|UniProtKB=A0ACM8EDY5 A0ACM8EDY5 PTHR22984:SF33 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120846705|UniProtKB=A0ACM8F2R9 A0ACM8F2R9 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8043966|UniProtKB=A0ACM8DMB6 A0ACM8DMB6 LOC8043966 PTHR12383:SF16 PROTEASE FAMILY S26 MITOCHONDRIAL INNER MEMBRANE PROTEASE-RELATED MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 1 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120840448|UniProtKB=A0ACM8FRB6 A0ACM8FRB6 LOC120840448 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120839953|UniProtKB=A0ACM8EN39 A0ACM8EN39 LOC120839953 PTHR24264:SF65 TRYPSIN-RELATED DUF7495 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121833789|UniProtKB=A0ACM8FN15 A0ACM8FN15 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115313800|UniProtKB=A0ACM8DT78 A0ACM8DT78 LOC115313800 PTHR24381:SF486 ZINC FINGER PROTEIN ADULT ENHANCER FACTOR 1-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115316828|UniProtKB=A0ACM8ETG4 A0ACM8ETG4 LOC115316828 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120848056|UniProtKB=A0ACM8F540 A0ACM8F540 LOC120848056 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837137|UniProtKB=A0ACM8EGN4 A0ACM8EGN4 LOC120837137 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8042832|UniProtKB=A0ACM8FWK0 A0ACM8FWK0 LOC8042832 PTHR19850:SF43 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-2 signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117;G-protein#PC00020;protein-binding activity modulator#PC00095 Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Wnt signaling pathway#P00057>GBeta#P01457;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;PI3 kinase pathway#P00048>Gbetagamma#P01188;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012 IXOSC|EnsemblGenome=LOC8024730|UniProtKB=A0ACM8E0R9 A0ACM8E0R9 LOC8024730 PTHR43975:SF2 ZGC:101858 DEHYDROGENASES, SHORT CHAIN IXOSC|EnsemblGenome=LOC120846079|UniProtKB=A0ACM8F0T4 A0ACM8F0T4 LOC120846079 PTHR24416:SF349 TYROSINE-PROTEIN KINASE RECEPTOR INACTIVE TYROSINE-PROTEIN KINASE RYK transmembrane signaling receptor activity#GO:0004888;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121836287|UniProtKB=A0ACM8FY66 A0ACM8FY66 LOC121836287 PTHR10484:SF162 HISTONE H4 HISTONE H4-LIKE PROTEIN TYPE G structural molecule activity#GO:0005198 chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8028428|UniProtKB=A0ACM8DGF3 A0ACM8DGF3 LOC8028428 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC121833204|UniProtKB=A0ACM8FJY8 A0ACM8FJY8 LOC121833204 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120850149|UniProtKB=A0ACM8F978 A0ACM8F978 LOC120850149 PTHR45620:SF44 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTOR, ORPHAN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115312306|UniProtKB=A0ACM8G0N8 A0ACM8G0N8 LOC115312306 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842138|UniProtKB=A0ACM8EU88 A0ACM8EU88 LOC120842138 PTHR11473:SF15 AROMATIC AMINO ACID HYDROXYLASE TYROSINE 3-MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 multicellular organismal reproductive process#GO:0048609;cell communication#GO:0007154;nervous system process#GO:0050877;trans-synaptic signaling#GO:0099537;cognition#GO:0050890;reproductive process#GO:0022414;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;system process#GO:0003008;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;synaptic transmission, dopaminergic#GO:0001963;synaptic signaling#GO:0099536 axon#GO:0030424;intracellular anatomical structure#GO:0005622;perikaryon#GO:0043204;neuron projection#GO:0043005;cell body#GO:0044297;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Dopamine receptor mediated signaling pathway#P05912>TH#P05970;Adrenaline and noradrenaline biosynthesis#P00001>TH#P00062 IXOSC|EnsemblGenome=LOC115323388|UniProtKB=A0ACM8FAN8 A0ACM8FAN8 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8036311|UniProtKB=A0ACM8EJ32 A0ACM8EJ32 PTHR24179:SF29 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 LD46604P enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8035532|UniProtKB=A0ACM8DGL7 A0ACM8DGL7 LOC8035532 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623 IXOSC|EnsemblGenome=LOC8024539|UniProtKB=A0ACM8FQS4 A0ACM8FQS4 zfh1 PTHR24391:SF27 HISTONE H4 TRANSCRIPTION FACTOR-RELATED ZINC FINGER PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8031554|UniProtKB=A0ACM8G527 A0ACM8G527 RhoGAP68F PTHR45808:SF23 RHO GTPASE-ACTIVATING PROTEIN 68F RHO GTPASE-ACTIVATING PROTEIN 68F enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;negative regulation of biological process#GO:0048519;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 PDGF signaling pathway#P00047>Rho#P01174;VEGF signaling pathway#P00056>Rac#P01421;Angiogenesis#P00005>Rac#P00245;Cytoskeletal regulation by Rho GTPase#P00016>Rho GAPs#P00520 IXOSC|EnsemblGenome=LOC8028206|UniProtKB=A0ACM8FU70 A0ACM8FU70 LOC8028206 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115333015|UniProtKB=A0ACM8F6U7 A0ACM8F6U7 LOC115333015 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC120848667|UniProtKB=A0ACM8FJ59 A0ACM8FJ59 LOC120848667 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8035557|UniProtKB=A0ACM8E2Q9 A0ACM8E2Q9 Alg14 PTHR12154:SF4 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020 transferase#PC00220 IXOSC|EnsemblGenome=LOC120848949|UniProtKB=A0ACM8F6P4 A0ACM8F6P4 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121046485|UniProtKB=A0ACM8FDZ5 A0ACM8FDZ5 LOC121046485 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8032357|UniProtKB=A0ACM8E635 A0ACM8E635 LOC8032357 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120849453|UniProtKB=A0ACM8F8T2 A0ACM8F8T2 LOC120849453 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8035057|UniProtKB=A0ACM8FEW2 A0ACM8FEW2 ATP8A PTHR24092:SF150 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8026338|UniProtKB=A0ACM8FD85 A0ACM8FD85 l(2)37Cg PTHR13946:SF28 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 IXOSC|EnsemblGenome=LOC120843862|UniProtKB=A0ACM8EWR3 A0ACM8EWR3 LOC120843862 PTHR46473:SF22 GH08155P LEUCINE-RICH IMMUNE PROTEIN (TM) IXOSC|EnsemblGenome=LOC115328492|UniProtKB=A0ACM8FTD8 A0ACM8FTD8 LOC115328492 PTHR32465:SF0 BARDET-BIEDL SYNDROME 2 PROTEIN BBSOME COMPLEX MEMBER BBS2 plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cilium#GO:0005929;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;neuron projection#GO:0043005;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;BBSome#GO:0034464 IXOSC|EnsemblGenome=LOC120836474|UniProtKB=A0ACM8EFQ7 A0ACM8EFQ7 LOC120836474 PTHR19134:SF449 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 9 protein modifying enzyme#PC00260;protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8033483|UniProtKB=A0ACM8G0K5 A0ACM8G0K5 LOC8033483 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8044148|UniProtKB=A0ACM8E297 A0ACM8E297 LOC8044148 PTHR13126:SF0 CHAPERONE ATP11 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 1 mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8051950|UniProtKB=A0ACM8DW68 A0ACM8DW68 LOC8051950 PTHR22624:SF60 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;autophagy#GO:0006914;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;autophagosome assembly#GO:0000045;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;proteolysis#GO:0006508;organelle assembly#GO:0070925;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8026575|UniProtKB=A0ACM8FZ46 A0ACM8FZ46 LOC8026575 PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC8029161|UniProtKB=A0ACM8E6I6 A0ACM8E6I6 eIF2beta PTHR23001:SF3 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 2 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;protein binding#GO:0005515;RNA binding#GO:0003723;translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743;translation initiation factor binding#GO:0031369 protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;cytoplasmic translational initiation#GO:0002183;translational initiation#GO:0006413;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8025158|UniProtKB=A0ACM8DJ25 A0ACM8DJ25 Tmem18 PTHR22593:SF2 TRANSMEMBRANE PROTEIN 18 TRANSMEMBRANE PROTEIN 18 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane#GO:0016020;organelle envelope#GO:0031967 IXOSC|EnsemblGenome=LOC115316261|UniProtKB=A0ACM8EYN1 A0ACM8EYN1 LOC115316261 PTHR15614:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 81 HOMOLOG protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;microtubule-based transport#GO:0099111;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cellular component organization#GO:0016043 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990 IXOSC|EnsemblGenome=LOC115319594|UniProtKB=A0ACM8G221 A0ACM8G221 LOC115319594 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8053389|UniProtKB=A0ACM8DTS8 A0ACM8DTS8 LOC8053389 PTHR12081:SF107 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F3-LIKE ISOFORM X1 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC115322558|UniProtKB=A0ACM8EML5 A0ACM8EML5 LOC115322558 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8043859|UniProtKB=A0ACM8E238 A0ACM8E238 LOC8043859 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120836511|UniProtKB=A0ACM8FNR6 A0ACM8FNR6 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8032248|UniProtKB=A0ACM8DYU7 A0ACM8DYU7 brun PTHR21512:SF5 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular vesicle#GO:0097708;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;Golgi apparatus subcompartment#GO:0098791;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802 IXOSC|EnsemblGenome=LOC8053546|UniProtKB=A0ACM8G0Y2 A0ACM8G0Y2 LOC8053546 PTHR12101:SF31 POPEYE DOMAIN CONTAINING PROTEIN BLOOD VESSEL EPICARDIAL SUBSTANCE-LIKE PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367 regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;regulation of biological quality#GO:0065008;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 apical junction complex#GO:0043296;anchoring junction#GO:0070161;tight junction#GO:0070160;cell junction#GO:0030054;sarcolemma#GO:0042383;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923 IXOSC|EnsemblGenome=LOC115331727|UniProtKB=A0ACM8ECX2 A0ACM8ECX2 LOC115331727 PTHR21230:SF89 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B binding#GO:0005488;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;SNAP receptor activity#GO:0005484 post-Golgi vesicle-mediated transport#GO:0006892;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152;endosomal transport#GO:0016197;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;vesicle fusion#GO:0006906;catabolic process#GO:0009056;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization#GO:0051234;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;membrane organization#GO:0061024;macroautophagy#GO:0016236 cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;endoplasmic reticulum#GO:0005783;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;membrane#GO:0016020;vesicle membrane#GO:0012506;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134 membrane traffic protein#PC00150;SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 IXOSC|EnsemblGenome=LOC8036259|UniProtKB=A0ACM8EAW8 A0ACM8EAW8 LOC8036259 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8043326|UniProtKB=A0ACM8DL40 A0ACM8DL40 LOC8043326 PTHR37159:SF1 GH11867P GH11867P IXOSC|EnsemblGenome=LOC120838855|UniProtKB=A0ACM8EK43 A0ACM8EK43 LOC120838855 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC120836093|UniProtKB=A0ACM8ERE0 A0ACM8ERE0 LOC120836093 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8034235|UniProtKB=A0ACM8E5Q3 A0ACM8E5Q3 LOC8034235 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8028282|UniProtKB=A0ACM8E501 A0ACM8E501 LOC8028282 PTHR13793:SF164 PHD FINGER PROTEINS ALHAMBRA, ISOFORM P histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115324234|UniProtKB=A0ACM8ET92 A0ACM8ET92 LOC115324234 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115322399|UniProtKB=A0ACM8E2W6 A0ACM8E2W6 LOC115322399 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8038511|UniProtKB=A0ACM8DTD7 A0ACM8DTD7 LOC8038511 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115321232|UniProtKB=A0ACM8EN06 A0ACM8EN06 LOC115321232 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115312543|UniProtKB=A0ACM8EZ45 A0ACM8EZ45 LOC115312543 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8028028|UniProtKB=A0ACM8DJJ3 A0ACM8DJJ3 LOC8028028 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120846356|UniProtKB=A0ACM8F264 A0ACM8F264 Hou PTHR12864:SF85 RAN BINDING PROTEIN 9-RELATED GLUCOSE-INDUCED DEGRADATION PROTEIN 8 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115324557|UniProtKB=A0ACM8F3F4 A0ACM8F3F4 LOC115324557 PTHR47526:SF4 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121833853|UniProtKB=A0ACM8FNE9 A0ACM8FNE9 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;reproductive process#GO:0022414;homologous recombination#GO:0035825;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;response to stimulus#GO:0050896;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;nucleotide-excision repair#GO:0006289;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120838415|UniProtKB=A0ACM8EJX8 A0ACM8EJX8 LOC120838415 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121833178|UniProtKB=A0ACM8FJV1 A0ACM8FJV1 LOC121833178 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318970|UniProtKB=A0ACM8DYK8 A0ACM8DYK8 LOC115318970 PTHR47968:SF13 CENTROMERE PROTEIN E KINESIN-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115328745|UniProtKB=A0ACM8EA21 A0ACM8EA21 LOC115328745 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8036090|UniProtKB=A0ACM8DJW6 A0ACM8DJW6 LOC8036090 PTHR46880:SF5 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050964|UniProtKB=A0ACM8E094 A0ACM8E094 oaf PTHR13423:SF2 OUT AT FIRST OUT AT FIRST PROTEIN HOMOLOG IXOSC|EnsemblGenome=LOC120845896|UniProtKB=A0ACM8F0S1 A0ACM8F0S1 Tcs3 PTHR11735:SF14 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120842681|UniProtKB=A0ACM8EUC6 A0ACM8EUC6 LOC120842681 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310972|UniProtKB=A0ACM8DQH2 A0ACM8DQH2 LOC115310972 PTHR11592:SF135 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 oxidoreductase#PC00176;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC115321898|UniProtKB=A0ACM8E1G5 A0ACM8E1G5 ND-75 PTHR11615:SF377 NITRATE, FORMATE, IRON DEHYDROGENASE NADH-UBIQUINONE OXIDOREDUCTASE 75 KDA SUBUNIT, MITOCHONDRIAL electron transfer activity#GO:0009055;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;NADH dehydrogenase activity#GO:0003954;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;primary active transmembrane transporter activity#GO:0015399;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152 mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex I#GO:0045271;organelle membrane#GO:0031090;transporter complex#GO:1990351;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8042814|UniProtKB=A0ACM8DU20 A0ACM8DU20 ND-B17 PTHR21106:SF2 NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 6 GM23292P protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 IXOSC|EnsemblGenome=LOC8034226|UniProtKB=A0ACM8E8I3 A0ACM8E8I3 LOC8034226 PTHR10978:SF5 SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT SUCCINATE DEHYDROGENASE CYTOCHROME B560 SUBUNIT, MITOCHONDRIAL electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060 respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803 dehydrogenase#PC00092 TCA cycle#P00051>Succinate Dehydrogenase#P01273 IXOSC|EnsemblGenome=LOC120841303|UniProtKB=A0ACM8ER85 A0ACM8ER85 LOC120841303 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029721|UniProtKB=A0ACM8E2M9 A0ACM8E2M9 LOC8029721 PTHR44656:SF7 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 12 DEHYDROGENASE_REDUCTASE SDR FAMILY MEMBER 12 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121834174|UniProtKB=A0ACM8FP41 A0ACM8FP41 PTHR22984:SF33 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120846644|UniProtKB=A0ACM8F2W7 A0ACM8F2W7 LOC120846644 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034031|UniProtKB=A0ACM8EPC5 A0ACM8EPC5 LOC8034031 PTHR16442:SF1 RING FINGER PROTEIN 17 RING FINGER PROTEIN 17 IXOSC|EnsemblGenome=LOC115327644|UniProtKB=A0ACM8E7W9 A0ACM8E7W9 LOC115327644 PTHR46457:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 DNA REPAIR PROTEIN RAD51 HOMOLOG 4 four-way junction DNA binding#GO:0000400;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;organelle fission#GO:0048285;telomere organization#GO:0032200;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;homologous recombination#GO:0035825;reproductive process#GO:0022414;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;nucleobase-containing compound metabolic process#GO:0006139;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987 replication fork#GO:0005657;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120844194|UniProtKB=A0ACM8EY59 A0ACM8EY59 LOC120844194 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843265|UniProtKB=A0ACM8EVQ7 A0ACM8EVQ7 LOC120843265 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313934|UniProtKB=A0ACM8EGB4 A0ACM8EGB4 Mettl4 PTHR12829:SF4 N6-ADENOSINE-METHYLTRANSFERASE LD37858P transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8034367|UniProtKB=A0ACM8F8H8 A0ACM8F8H8 Ubc2 PTHR24068:SF41 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2-24 KDA aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121047009|UniProtKB=A0ACM8FFF4 A0ACM8FFF4 LOC121047009 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052063|UniProtKB=A0ACM8EXQ0 A0ACM8EXQ0 LOC8052063 PTHR45620:SF40 PDF RECEPTOR-LIKE PROTEIN-RELATED G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121834299|UniProtKB=A0ACM8FQT0 A0ACM8FQT0 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120845771|UniProtKB=A0ACM8FH24 A0ACM8FH24 LOC120845771 PTHR10643:SF2 KINETOCHORE PROTEIN NDC80 KINETOCHORE PROTEIN NDC80 HOMOLOG chromosome localization#GO:0050000;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic metaphase chromosome alignment#GO:0007080;organelle fission#GO:0048285;localization#GO:0051179;nuclear division#GO:0000280;organelle localization#GO:0051640;attachment of mitotic spindle microtubules to kinetochore#GO:0051315 kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC120848584|UniProtKB=A0ACM8F544 A0ACM8F544 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327283|UniProtKB=A0ACM8FJB7 A0ACM8FJB7 LOC115327283 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8024781|UniProtKB=A0ACM8DIP4 A0ACM8DIP4 Prp18 PTHR13007:SF19 PRE-MRNA SPLICING FACTOR-RELATED PRE-MRNA-SPLICING FACTOR 18 cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120850733|UniProtKB=A0ACM8FAR4 A0ACM8FAR4 LOC120850733 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120850723|UniProtKB=A0ACM8FAX4 A0ACM8FAX4 LOC120850723 PTHR10314:SF194 CYSTATHIONINE BETA-SYNTHASE CYSTATHIONINE BETA-SYNTHASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lyase#PC00144 Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887 IXOSC|EnsemblGenome=LOC115316987|UniProtKB=A0ACM8FXV8 A0ACM8FXV8 LOC121836061 PTHR31184:SF2 HUNTINGTIN-INTERACTING PROTEIN K FAMILY MEMBER HUNTINGTIN-INTERACTING PROTEIN K biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;regulation of protein stability#GO:0031647;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;protein stabilization#GO:0050821;regulation of biological quality#GO:0065008;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 IXOSC|EnsemblGenome=LOC8032757|UniProtKB=A0ACM8F6I4 A0ACM8F6I4 LOC8032757 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8033688|UniProtKB=A0ACM8DRH9 A0ACM8DRH9 LOC8033688 PTHR12215:SF10 PHOSPHOPANTETHEINE TRANSFERASE L-AMINOADIPATE-SEMIALDEHYDE DEHYDROGENASE-PHOSPHOPANTETHEINYL TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8031556|UniProtKB=A0ACM8EMZ8 A0ACM8EMZ8 LOC8031556 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120842665|UniProtKB=A0ACM8EUB4 A0ACM8EUB4 LOC120842665 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121045941|UniProtKB=A0ACM8FDK3 A0ACM8FDK3 LOC121045941 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034135|UniProtKB=A0ACM8DIZ6 A0ACM8DIZ6 PGAP3 PTHR13148:SF0 PER1-RELATED GPI-SPECIFIC PHOSPHOLIPASE A2-LIKE PGAP3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115320994|UniProtKB=A0ACM8FWR2 A0ACM8FWR2 LOC115320994 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8041619|UniProtKB=A0ACM8DKR3 A0ACM8DKR3 LOC8041619 PTHR12121:SF45 CARBON CATABOLITE REPRESSOR PROTEIN 4 NOCTURNIN hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC8032717|UniProtKB=A0ACM8G6R2 A0ACM8G6R2 LOC8032717 PTHR12308:SF91 ANOCTAMIN ANOCTAMIN transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;intramembrane lipid carrier activity#GO:0140303 lipid transport#GO:0006869;phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;macromolecule localization#GO:0033036;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8027838|UniProtKB=A0ACM8EE32 A0ACM8EE32 LOC8027838 PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC120846013|UniProtKB=A0ACM8F180 A0ACM8F180 LOC120846013 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120837808|UniProtKB=A0ACM8EHV5 A0ACM8EHV5 LOC120837808 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121836539|UniProtKB=A0ACM8FZ39 A0ACM8FZ39 LOC121836539 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8038234|UniProtKB=A0ACM8EG93 A0ACM8EG93 LOC8038234 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8030341|UniProtKB=A0ACM8FHL5 A0ACM8FHL5 LOC8030341 PTHR11918:SF45 RADICAL SAM PROTEINS THREONYLCARBAMOYLADENOSINE TRNA METHYLTHIOTRANSFERASE catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a tRNA#GO:0140101 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC8035728|UniProtKB=A0ACM8EEV6 A0ACM8EEV6 LOC8035728 PTHR10075:SF100 BASIGIN RELATED PROTEIN SAX-3 cell adhesion molecule#PC00069 Axon guidance mediated by Slit/Robo#P00008>Robo#P00348 IXOSC|EnsemblGenome=LOC120841597|UniProtKB=A0ACM8ET23 A0ACM8ET23 LOC120841597 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8038929|UniProtKB=A0ACM8E3N9 A0ACM8E3N9 LOC8038929 PTHR11215:SF1 METAL DEPENDENT HYDROLASE - RELATED MYG1 EXONUCLEASE hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8035253|UniProtKB=A0ACM8DVQ2 A0ACM8DVQ2 LOC8035253 PTHR20854:SF4 INOSITOL MONOPHOSPHATASE INOSITOL-1-MONOPHOSPHATASE-RELATED hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC120837629|UniProtKB=A0ACM8EIK9 A0ACM8EIK9 LOC120837629 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115330560|UniProtKB=A0ACM8EVQ6 A0ACM8EVQ6 LOC115330560 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121048089|UniProtKB=A0ACM8G800 A0ACM8G800 LOC121048089 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053923|UniProtKB=A0ACM8E194 A0ACM8E194 LOC8053923 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121836065|UniProtKB=A0ACM8FXW6 A0ACM8FXW6 LOC121836065 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120844027|UniProtKB=A0ACM8EXL0 A0ACM8EXL0 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026380|UniProtKB=A0ACM8EL31 A0ACM8EL31 LOC8026380 PTHR14939:SF5 F-BOX ONLY PROTEIN 22 FIST C-DOMAIN DOMAIN-CONTAINING PROTEIN ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 IXOSC|EnsemblGenome=LOC8052404|UniProtKB=A0ACM8EDE9 A0ACM8EDE9 PTHR22950:SF652 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8026555|UniProtKB=A0ACM8DRJ4 A0ACM8DRJ4 LOC8026555 PTHR12608:SF1 TRANSMEMBRANE PROTEIN HTP-1 RELATED DIVALENT CATION_PROTON ANTIPORTER TMEM165-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120842141|UniProtKB=A0ACM8ESX0 A0ACM8ESX0 LOC120842141 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8036885|UniProtKB=A0ACM8EZP9 A0ACM8EZP9 LOC8036885 PTHR46674:SF1 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 INACTIVE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP6 heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;binding#GO:0005488;protein binding#GO:0005515 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;piRNA processing#GO:0034587;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;male gamete generation#GO:0048232;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8036544|UniProtKB=A0ACM8E8C8 A0ACM8E8C8 PTHR12103:SF12 5'-NUCLEOTIDASE DOMAIN-CONTAINING FI20020P1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 nucleotide phosphatase#PC00173;hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115325960|UniProtKB=A0ACM8FA29 A0ACM8FA29 LOC115325960 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115329187|UniProtKB=A0ACM8G1C0 A0ACM8G1C0 LOC115329187 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120849496|UniProtKB=A0ACM8F6X8 A0ACM8F6X8 LOC120849496 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842344|UniProtKB=A0ACM8FGI5 A0ACM8FGI5 LOC120842344 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8031502|UniProtKB=A0ACM8DIB9 A0ACM8DIB9 LOC8031502 PTHR13415:SF2 NUCLEAR FACTOR-RELATED INTEGRATOR COMPLEX SUBUNIT 12 snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;integrator complex#GO:0032039 IXOSC|EnsemblGenome=LOC120841959|UniProtKB=A0ACM8ESG2 A0ACM8ESG2 LOC120841959 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042702|UniProtKB=A0ACM8F949 A0ACM8F949 LOC8042702 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT AT04468P-RELATED ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;cation-transporting ATPase complex#GO:0090533;membrane#GO:0016020;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8053034|UniProtKB=A0ACM8DLJ4 A0ACM8DLJ4 LOC8053034 PTHR43382:SF2 PROLYL-TRNA SYNTHETASE BIFUNCTIONAL GLUTAMATE_PROLINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039 catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 Heme biosynthesis#P02746>Glutamyl-tRNA-synthetase#P02977 IXOSC|EnsemblGenome=LOC8040883|UniProtKB=A0ACM8FIB8 A0ACM8FIB8 LOC8040883 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8041709|UniProtKB=A0ACM8EY29 A0ACM8EY29 LOC8041709 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;transport#GO:0006810;sodium ion transport#GO:0006814 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120846404|UniProtKB=A0ACM8F206 A0ACM8F206 LOC120846404 PTHR10117:SF54 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN transporter activity#GO:0005215;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;channel activity#GO:0015267 homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 IXOSC|EnsemblGenome=LOC120840032|UniProtKB=A0ACM8ENA1 A0ACM8ENA1 LOC120840032 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321484|UniProtKB=A0ACM8E1T8 A0ACM8E1T8 LOC115321484 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843371|UniProtKB=A0ACM8EVX7 A0ACM8EVX7 LOC120843371 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039810|UniProtKB=A0ACM8EI28 A0ACM8EI28 LOC8039810 PTHR47958:SF216 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;gamete generation#GO:0007276;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;reproductive process#GO:0022414;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8041332|UniProtKB=A0ACM8DKN9 A0ACM8DKN9 LOC8041332 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8029656|UniProtKB=A0ACM8FM53 A0ACM8FM53 LOC8029656 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC115328279|UniProtKB=A0ACM8EHT5 A0ACM8EHT5 LOC115328279 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC115313586|UniProtKB=A0ACM8EZP1 A0ACM8EZP1 LOC115313586 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039107|UniProtKB=A0ACM8DKC1 A0ACM8DKC1 PTHR19876:SF2 COATOMER COATOMER SUBUNIT BETA' localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659 vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC115320237|UniProtKB=A0ACM8E125 A0ACM8E125 LOC115320237 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121836523|UniProtKB=A0ACM8FZ26 A0ACM8FZ26 LOC121836523 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026373|UniProtKB=A0ACM8EJ14 A0ACM8EJ14 LOC8026373 PTHR11690:SF296 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED DEGENERIN-LIKE PROTEIN DEL-10 monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC120844207|UniProtKB=A0ACM8FYJ4 A0ACM8FYJ4 LOC120844207 PTHR11640:SF169 NEPHRIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8027327|UniProtKB=A0ACM8ECQ4 A0ACM8ECQ4 LOC8027327 PTHR10104:SF1 STATHMIN STATHMIN, ISOFORM D protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;protein-containing complex disassembly#GO:0032984;regulation of microtubule-based process#GO:0032886;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;system development#GO:0048731;microtubule polymerization or depolymerization#GO:0031109;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;protein depolymerization#GO:0051261;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;cell projection organization#GO:0030030;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular component disassembly#GO:0022411;neuron development#GO:0048666;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;microtubule depolymerization#GO:0007019;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933 neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8041558|UniProtKB=A0ACM8DYS4 A0ACM8DYS4 Hsp83 PTHR11528:SF34 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 83 nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ATP-dependent activity#GO:0140657;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP binding#GO:0005524 protein folding#GO:0006457;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to temperature stimulus#GO:0009266;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of protein stability#GO:0031647;response to stress#GO:0006950;cellular response to heat#GO:0034605;response to heat#GO:0009408;protein stabilization#GO:0050821;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;perinuclear region of cytoplasm#GO:0048471;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 chaperone#PC00072;Hsp90 family chaperone#PC00028 IXOSC|EnsemblGenome=LOC8051110|UniProtKB=A0ACM8EC30 A0ACM8EC30 LOC8051110 PTHR12904:SF22 FAMILY NOT NAMED ZYG-11 FAMILY MEMBER A, CELL CYCLE REGULATOR catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul2-RING ubiquitin ligase complex#GO:0031462;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC120836544|UniProtKB=A0ACM8EG87 A0ACM8EG87 LOC120836544 PTHR13425:SF3 HEADCASE PROTEIN HEADCASE PROTEIN HOMOLOG IXOSC|EnsemblGenome=LOC120843125|UniProtKB=A0ACM8EVD1 A0ACM8EVD1 TM9SF4 PTHR10766:SF188 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 4 macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;localization within membrane#GO:0051668;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120849845|UniProtKB=A0ACM8F8W4 A0ACM8F8W4 LOC120849845 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC120845828|UniProtKB=A0ACM8FVF8 A0ACM8FVF8 GluRIB PTHR18966:SF602 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC115325048|UniProtKB=A0ACM8E5I0 A0ACM8E5I0 LOC115325048 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC115315207|UniProtKB=A0ACM8EPN8 A0ACM8EPN8 LOC115315207 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841903|UniProtKB=A0ACM8ESN6 A0ACM8ESN6 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115318456|UniProtKB=A0ACM8FJ83 A0ACM8FJ83 LOC115318456 PTHR16216:SF11 DYNEIN ASSEMBLY FACTOR 5, AXONEMAL DYNEIN AXONEMAL ASSEMBLY FACTOR 5 binding#GO:0005488;protein binding#GO:0005515 plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;outer dynein arm assembly#GO:0036158;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;protein-containing complex assembly#GO:0065003;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;axoneme assembly#GO:0035082;microtubule cytoskeleton organization#GO:0000226;microtubule bundle formation#GO:0001578;axonemal dynein complex assembly#GO:0070286;inner dynein arm assembly#GO:0036159;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8051171|UniProtKB=A0ACM8DLY1 A0ACM8DLY1 LOC8051171 PTHR15032:SF38 N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D N-ACYL-PHOSPHATIDYLETHANOLAMINE-HYDROLYZING PHOSPHOLIPASE D lipase activity#GO:0016298;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;glycerophospholipid metabolic process#GO:0006650 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell body#GO:0044297;neuron projection#GO:0043005;intracellular anatomical structure#GO:0005622 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC8025806|UniProtKB=A0ACM8FJ79 A0ACM8FJ79 eas PTHR22603:SF66 CHOLINE/ETHANOALAMINE KINASE ETHANOLAMINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137 IXOSC|EnsemblGenome=LOC115331210|UniProtKB=A0ACM8EPV3 A0ACM8EPV3 LOC115331210 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115308308|UniProtKB=A0ACM8G2J2 A0ACM8G2J2 LOC115308308 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8027399|UniProtKB=A0ACM8DJ11 A0ACM8DJ11 LOC8027399 PTHR20920:SF5 RPE-SPONDIN VEXED, ISOFORM B IXOSC|EnsemblGenome=LOC8027265|UniProtKB=A0ACM8E2Q0 A0ACM8E2Q0 LOC8027265 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115323696|UniProtKB=A0ACM8EQU5 A0ACM8EQU5 LOC115323696 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8042536|UniProtKB=A0ACM8E2E8 A0ACM8E2E8 LOC8042536 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115327302|UniProtKB=A0ACM8E7I8 A0ACM8E7I8 LOC115327302 PTHR31786:SF2 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24 FANCONI ANEMIA CORE COMPLEX-ASSOCIATED PROTEIN 24 chromatin binding#GO:0003682;binding#GO:0005488 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120850600|UniProtKB=A0ACM8F965 A0ACM8F965 LOC120850600 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8037031|UniProtKB=A0ACM8DZX4 A0ACM8DZX4 mRpL48 PTHR13473:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L48 LARGE RIBOSOMAL SUBUNIT PROTEIN ML48 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120837699|UniProtKB=A0ACM8EI10 A0ACM8EI10 LOC120837699 PTHR46569:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRAIP E3 UBIQUITIN-PROTEIN LIGASE TRAIP ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;replication fork processing#GO:0031297;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;protein modification by small protein conjugation#GO:0032446;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;DNA-templated DNA replication#GO:0006261 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8033068|UniProtKB=A0ACM8DS36 A0ACM8DS36 LOC8033068 PTHR21321:SF4 PNAS-3 RELATED EXOSOME COMPLEX COMPONENT RRP4 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;snRNA 3'-end processing#GO:0034472;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;cellular component biogenesis#GO:0044085;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120842066|UniProtKB=A0ACM8ET00 A0ACM8ET00 LOC120842066 PTHR45840:SF2 RHOMBOID-RELATED PROTEIN PROTEIN RHOMBOID-RELATED IXOSC|EnsemblGenome=LOC8044079|UniProtKB=A0ACM8FFI1 A0ACM8FFI1 LOC8044079 PTHR13815:SF7 GOLGIN-84 GOLGIN SUBFAMILY A MEMBER 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;retrograde transport, vesicle recycling within Golgi#GO:0000301;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi stack#GO:0005795;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985 IXOSC|EnsemblGenome=LOC121834536|UniProtKB=A0ACM8FNY8 A0ACM8FNY8 PTHR46103:SF3 RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8037999|UniProtKB=A0ACM8F5G9 A0ACM8F5G9 PTHR10369:SF3 60S RIBOSOMAL PROTEIN L36A/L44 RIBOSOMAL PROTEIN L36A structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115327537|UniProtKB=A0ACM8EUM2 A0ACM8EUM2 LOC115327537 PTHR20855:SF152 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular response to chemical stimulus#GO:0070887;cytokine-mediated signaling pathway#GO:0019221;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;response to peptide#GO:1901652;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8030959|UniProtKB=A0ACM8DZR7 A0ACM8DZR7 LOC8030959 PTHR42886:SF96 RE40534P-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate biosynthetic process#GO:0090407;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115308454|UniProtKB=A0ACM8F7S1 A0ACM8F7S1 LOC115308454 PTHR22930:SF269 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034464|UniProtKB=A0ACM8E4N1 A0ACM8E4N1 LOC8034464 PTHR12544:SF52 GLUTAMINASE GLUTAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8041569|UniProtKB=A0ACM8ECH3 A0ACM8ECH3 LOC8041569 PTHR24403:SF67 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115329103|UniProtKB=A0ACM8E9I6 A0ACM8E9I6 LOC115329103 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120848891|UniProtKB=A0ACM8F6Z8 A0ACM8F6Z8 LOC120848891 PTHR46708:SF2 TENASCIN FIBRONECTIN-LIKE extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8041497|UniProtKB=A0ACM8DXK4 A0ACM8DXK4 LOC8041497 PTHR12656:SF14 BRG-1 ASSOCIATED FACTOR 250 BAF250 TRITHORAX GROUP PROTEIN OSA chromatin binding#GO:0003682;binding#GO:0005488;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC120840673|UniProtKB=A0ACM8EQP5 A0ACM8EQP5 LOC120840673 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8029374|UniProtKB=A0ACM8FWC0 A0ACM8FWC0 LOC8029374 PTHR43243:SF109 INNER MEMBRANE TRANSPORTER YGJI-RELATED AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 amino acid transport#GO:0006865;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;amino acid transporter#PC00046 IXOSC|EnsemblGenome=LOC120841033|UniProtKB=A0ACM8FV27 A0ACM8FV27 LOC120841033 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120840615|UniProtKB=A0ACM8EPG8 A0ACM8EPG8 LOC120840615 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8051903|UniProtKB=A0ACM8FFQ9 A0ACM8FFQ9 LOC8051903 PTHR11003:SF291 POTASSIUM CHANNEL, SUBFAMILY K TWO PORE POTASSIUM CHANNEL PROTEIN SUP-9 transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8023671|UniProtKB=A0ACM8FQ45 A0ACM8FQ45 LOC8023671 PTHR14030:SF29 MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1 MITOTIC CHECKPOINT SERINE_THREONINE-PROTEIN KINASE BUB1 BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cell cycle process#GO:0010564;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;meiotic sister chromatid cohesion#GO:0051177;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;negative regulation of chromosome segregation#GO:0051985;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;chromosome organization#GO:0051276;negative regulation of chromosome separation#GO:1905819;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of chromosome organization#GO:0033044;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;sister chromatid cohesion#GO:0007062;cell communication#GO:0007154;negative regulation of chromosome organization#GO:2001251 chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8035592|UniProtKB=A0ACM8E6R2 A0ACM8E6R2 RnrL PTHR11573:SF6 RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE CHAIN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE LARGE SUBUNIT purine ribonucleoside triphosphate binding#GO:0035639;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;oxidoreductase activity#GO:0016491;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;anion binding#GO:0043168;binding#GO:0005488;ATP binding#GO:0005524;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 biosynthetic process#GO:0009058;cellular process#GO:0009987;metabolic process#GO:0008152 oxidoreductase complex#GO:1990204;cytosol#GO:0005829;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>CDP Reductase#P02915;De novo purine biosynthesis#P02738>ADP reductase#P02902;De novo purine biosynthesis#P02738>GDP reductase#P02909;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>UDP reductase#P02921 IXOSC|EnsemblGenome=LOC8034084|UniProtKB=A0ACM8FJK6 A0ACM8FJK6 LOC8034084 PTHR11905:SF249 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN SOL NARAE, ISOFORM C metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121833536|UniProtKB=A0ACM8FLA8 A0ACM8FLA8 LOC121833536 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041137|UniProtKB=A0ACM8DYY9 A0ACM8DYY9 LOC8041137 PTHR35842:SF1 SI:CH211-67E16.11 SI:CH211-67E16.11 IXOSC|EnsemblGenome=LOC115327143|UniProtKB=A0ACM8EVB5 A0ACM8EVB5 LOC115327143 PTHR45913:SF5 EPM2A-INTERACTING PROTEIN 1 HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023807|UniProtKB=A0ACM8DYL0 A0ACM8DYL0 LOC8023807 PTHR15492:SF1 CYCLIN D1-BINDING PROTEIN 1 CYCLIN-D1-BINDING PROTEIN 1 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8033376|UniProtKB=A0ACM8DYU1 A0ACM8DYU1 LOC8033376 PTHR11552:SF233 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI02019P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120840393|UniProtKB=A0ACM8EP12 A0ACM8EP12 LOC120840393 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8029407|UniProtKB=A0ACM8DYU3 A0ACM8DYU3 LOC8029407 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8039728|UniProtKB=A0ACM8EFT5 A0ACM8EFT5 LOC8039728 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8026027|UniProtKB=A0ACM8F1B1 A0ACM8F1B1 LOC8026027 PTHR24403:SF48 ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 10 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120844861|UniProtKB=A0ACM8F0V9 A0ACM8F0V9 LOC120844861 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220 IXOSC|EnsemblGenome=ISCI021855|UniProtKB=B7Q5K1 B7Q5K1 ISCW021855 PTHR46064:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8038334|UniProtKB=A0ACM8DUT8 A0ACM8DUT8 LOC8038334 PTHR12378:SF80 DESUMOYLATING ISOPEPTIDASE IP06716P-RELATED catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC8026377|UniProtKB=A0ACM8DZY3 A0ACM8DZY3 PTHR11143:SF7 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER RIBOSOMAL PROTEIN L26 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8036199|UniProtKB=A0ACM8EV41 A0ACM8EV41 LOC8036199 PTHR11627:SF80 FRUCTOSE-BISPHOSPHATE ALDOLASE FRUCTOSE-BISPHOSPHATE ALDOLASE carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;fructose-bisphosphate aldolase activity#GO:0004332;lyase activity#GO:0016829 ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;primary metabolic process#GO:0044238;nucleoside diphosphate catabolic process#GO:0009134;purine nucleoside triphosphate metabolic process#GO:0009144;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 aldolase#PC00044;lyase#PC00144 Fructose galactose metabolism#P02744>Fructose bisphosphate aldolase#P02959;Glycolysis#P00024>Aldolase#P00679 IXOSC|EnsemblGenome=LOC115325241|UniProtKB=A0ACM8E4N2 A0ACM8E4N2 CCT1 PTHR11353:SF84 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ALPHA protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829;chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 IXOSC|EnsemblGenome=LOC8042352|UniProtKB=A0ACM8EFZ2 A0ACM8EFZ2 LOC8042352 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120839194|UniProtKB=A0ACM8EM66 A0ACM8EM66 LOC120839194 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;mitochondrial calcium ion homeostasis#GO:0051560;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987 mitochondrion#GO:0005739;calcium channel complex#GO:0034704;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;transporter complex#GO:1990351 calcium-binding protein#PC00060;calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC120839547|UniProtKB=A0ACM8ELG5 A0ACM8ELG5 LOC120839547 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8025030|UniProtKB=A0ACM8EQI6 A0ACM8EQI6 LOC8025030 PTHR11177:SF144 CHITINASE CHITINASE chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;chitin metabolic process#GO:0006030;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115313104|UniProtKB=A0ACM8EEM9 A0ACM8EEM9 LOC115313104 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309844|UniProtKB=A0ACM8DNZ8 A0ACM8DNZ8 LOC115309844 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328786|UniProtKB=A0ACM8F1E5 A0ACM8F1E5 LOC115328786 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8032815|UniProtKB=A0ACM8FB73 A0ACM8FB73 Sf3b3 PTHR10644:SF1 DNA REPAIR/RNA PROCESSING CPSF FAMILY SPLICING FACTOR 3B SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;snRNA binding#GO:0017069;RNA binding#GO:0003723 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;U2 snRNP#GO:0005686;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 RNA processing factor#PC00147;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8024494|UniProtKB=A0ACM8EFD2 A0ACM8EFD2 LOC8024494 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115323663|UniProtKB=A0ACM8G366 A0ACM8G366 LOC115323663 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC121835818|UniProtKB=A0ACM8FWP9 A0ACM8FWP9 LOC121835818 PTHR10848:SF0 MEIOTIC RECOMBINATION PROTEIN SPO11 MEIOTIC RECOMBINATION PROTEIN SPO11 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;organelle organization#GO:0006996;response to stress#GO:0006950;meiotic DNA double-strand break formation#GO:0042138;cellular process#GO:0009987;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;response to stimulus#GO:0050896;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;cell cycle process#GO:0022402;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716 chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC115308870|UniProtKB=A0ACM8FS79 A0ACM8FS79 LOC115308870 PTHR10680:SF39 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 IXOSC|EnsemblGenome=LOC115327265|UniProtKB=A0ACM8E7H0 A0ACM8E7H0 LOC115327265 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT AT04468P-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;transmembrane transport#GO:0055085;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;import into cell#GO:0098657;potassium ion import across plasma membrane#GO:1990573;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003 membrane protein complex#GO:0098796;membrane#GO:0016020;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;ATPase dependent transmembrane transport complex#GO:0098533 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8027228|UniProtKB=A0ACM8E7M9 A0ACM8E7M9 sol PTHR10183:SF382 CALPAIN CALPAIN-15 protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC121835953|UniProtKB=A0ACM8FXC1 A0ACM8FXC1 LOC121835953 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575 transferase#PC00220 IXOSC|EnsemblGenome=LOC8036832|UniProtKB=A0ACM8DXP0 A0ACM8DXP0 PTHR15192:SF8 PROTEIN CBG05349 OXIDATIVE STRESS INDUCED GROWTH INHIBITOR HOMOLOG OSGN-1 IXOSC|EnsemblGenome=LOC8027157|UniProtKB=A0ACM8E9E9 A0ACM8E9E9 PTHR10954:SF7 RIBONUCLEASE H2 SUBUNIT A RIBONUCLEASE H2 SUBUNIT A RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mismatch repair#GO:0006298;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 endoribonuclease#PC00094 DNA replication#P00017>RNase H#P00538 IXOSC|EnsemblGenome=LOC115323822|UniProtKB=A0ACM8E3C2 A0ACM8E3C2 LOC115323822 PTHR12475:SF4 FAMILY NOT NAMED PROTEIN THEM6 IXOSC|EnsemblGenome=LOC115321247|UniProtKB=A0ACM8EYP9 A0ACM8EYP9 LOC115321247 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120840819|UniProtKB=A0ACM8EQH4 A0ACM8EQH4 LOC120840819 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8040024|UniProtKB=A0ACM8E310 A0ACM8E310 PTHR24346:SF45 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SNF-RELATED SERINE_THREONINE-PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121836598|UniProtKB=A0ACM8G0K1 A0ACM8G0K1 LOC121836598 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN system development#GO:0048731;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;cell adhesion#GO:0007155;developmental process#GO:0032502;post-embryonic development#GO:0009791;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;heart development#GO:0007507;circulatory system development#GO:0072359;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8053807|UniProtKB=A0ACM8DU68 A0ACM8DU68 LOC8053807 PTHR11848:SF316 TGF-BETA FAMILY LD29161P-RELATED molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 ALP23B signaling pathway#P06209>ALP23B full length#P06225;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;MYO signaling pathway#P06215>myoglianin full length#P06315;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;TGF-beta signaling pathway#P00052>TGFbeta#P01286;MYO signaling pathway#P06215>myoglianin#P06312;ALP23B signaling pathway#P06209>ALP23B#P06223 IXOSC|EnsemblGenome=LOC115331285|UniProtKB=A0ACM8FV25 A0ACM8FV25 LOC115331285 PTHR46609:SF6 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN EXONUCLEASE, PHAGE-TYPE_RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8031770|UniProtKB=A0ACM8G4F4 A0ACM8G4F4 LOC8031770 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC120841709|UniProtKB=A0ACM8ES93 A0ACM8ES93 LOC120841709 PTHR24329:SF585 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8030577|UniProtKB=A0ACM8DPK6 A0ACM8DPK6 Rpn10 PTHR10223:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 proteasome complex#GO:0000502;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 protease#PC00190;protein modifying enzyme#PC00260 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC115331898|UniProtKB=A0ACM8ECN0 A0ACM8ECN0 LOC115331898 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120837428|UniProtKB=A0ACM8EI17 A0ACM8EI17 LOC120837428 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC121834071|UniProtKB=A0ACM8FNU8 A0ACM8FNU8 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395 metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;response to stimulus#GO:0050896;steroid metabolic process#GO:0008202;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466 intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115322762|UniProtKB=A0ACM8E391 A0ACM8E391 LOC115322762 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120840280|UniProtKB=A0ACM8FKI1 A0ACM8FKI1 LOC120840280 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120843221|UniProtKB=A0ACM8EVL5 A0ACM8EVL5 LOC120843221 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029768|UniProtKB=A0ACM8DIT0 A0ACM8DIT0 LOC8029768 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8053841|UniProtKB=A0ACM8DLQ8 A0ACM8DLQ8 LOC8053841 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8025940|UniProtKB=A0ACM8DYM8 A0ACM8DYM8 LOC8025940 PTHR11550:SF47 CTP SYNTHASE CTP SYNTHASE 1-RELATED identical protein binding#GO:0042802;ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;ligase activity#GO:0016874;catalytic activity#GO:0003824;binding#GO:0005488 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;supramolecular fiber#GO:0099512;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080 metabolite interconversion enzyme#PC00262;ligase#PC00142 De novo pyrimidine ribonucleotides biosythesis#P02740>CTP synthase#P02931 IXOSC|EnsemblGenome=LOC8028823|UniProtKB=A0ACM8DSZ0 A0ACM8DSZ0 LOC8028823 PTHR12027:SF115 WNT RELATED PROTEIN WNT protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664 neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;system development#GO:0048731;cell fate commitment#GO:0045165;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121835444|UniProtKB=A0ACM8FUQ1 A0ACM8FUQ1 LOC121835444 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121047513|UniProtKB=A0ACM8FH89 A0ACM8FH89 LOC121047513 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838016|UniProtKB=A0ACM8G688 A0ACM8G688 LOC121838016 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8024755|UniProtKB=A0ACM8G3D6 A0ACM8G3D6 LOC8024755 PTHR31061:SF38 LD22376P HEPARAN-ALPHA-GLUCOSAMINIDE N-ACETYLTRANSFERASE, ISOFORM A acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;glycoprotein metabolic process#GO:0009100 IXOSC|EnsemblGenome=LOC8052439|UniProtKB=A0ACM8ECW1 A0ACM8ECW1 LOC8052439 PTHR46116:SF26 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME UBIQUITIN-CONJUGATING ENZYME E2 Z aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8024882|UniProtKB=A0ACM8E9R4 A0ACM8E9R4 LOC8024882 PTHR35270:SF3 FUSELESS, ISOFORM A FUSELESS, ISOFORM A generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;trans-synaptic signaling#GO:0099537;system development#GO:0048731;neuron development#GO:0048666;cell communication#GO:0007154;anatomical structure development#GO:0048856;anatomical structure maturation#GO:0071695;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;anterograde trans-synaptic signaling#GO:0098916;cell differentiation#GO:0030154;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuromuscular synaptic transmission#GO:0007274;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;cell maturation#GO:0048469;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular process#GO:0009987;synaptic signaling#GO:0099536;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;nervous system development#GO:0007399;developmental maturation#GO:0021700;multicellular organismal process#GO:0032501 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8033258|UniProtKB=A0ACM8DHM0 A0ACM8DHM0 PTHR13287:SF2 ADIPOSE-SECRETED SIGNALING PROTEIN ADIPOSE-SECRETED SIGNALING PROTEIN adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8033377|UniProtKB=A0ACM8E5T0 A0ACM8E5T0 LOC8033377 PTHR10907:SF47 REGUCALCIN REGUCALCIN catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;regulation of calcium-mediated signaling#GO:0050848;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;esterase#PC00097 IXOSC|EnsemblGenome=LOC120837517|UniProtKB=A0ACM8EHJ9 A0ACM8EHJ9 LOC120837517 PTHR23254:SF16 EIF4G DOMAIN PROTEIN CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR translation regulator activity#GO:0045182 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8043251|UniProtKB=A0ACM8DL23 A0ACM8DL23 RpL3 PTHR11363:SF5 60S RIBOSOMAL PROTEIN L3-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL3 nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115316093|UniProtKB=A0ACM8EGS2 A0ACM8EGS2 PTHR10218:SF212 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA S SUBUNIT ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;sensory perception of chemical stimulus#GO:0007606;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;system process#GO:0003008;G protein-coupled dopamine receptor signaling pathway#GO:0007212;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to chemical#GO:0042221;multicellular organismal process#GO:0032501;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;sensory perception#GO:0007600;nervous system process#GO:0050877;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;cellular anatomical structure#GO:0110165 G-protein#PC00020;heterotrimeric G-protein#PC00117 5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Endothelin signaling pathway#P00019>Gs#P00584;Enkephalin release#P05913>G-Protein (s)#P05977 IXOSC|EnsemblGenome=LOC120840855|UniProtKB=A0ACM8EQ85 A0ACM8EQ85 LOC120840855 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8039275|UniProtKB=A0ACM8G1R5 A0ACM8G1R5 LOC8039275 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8023595|UniProtKB=A0ACM8FD78 A0ACM8FD78 LOC8023595 PTHR11219:SF69 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-A binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120843941|UniProtKB=A0ACM8EX93 A0ACM8EX93 LOC120843941 PTHR10838:SF34 SYNAPTOGYRIN SYNAPTOGYRIN organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120836388|UniProtKB=A0ACM8G7B5 A0ACM8G7B5 LOC120836388 PTHR46799:SF3 HOMEOBOX PROTEIN UNC-4 HOMOLOG HOMEOBOX PROTEIN UNC-4 nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC120836044|UniProtKB=A0ACM8EQC9 A0ACM8EQC9 LOC120836044 PTHR13005:SF4 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8051152|UniProtKB=A0ACM8DP06 A0ACM8DP06 LOC8051152 PTHR23287:SF18 RUBY-EYE2-LIKE PROTEIN BLOC-2 COMPLEX MEMBER HPS5 developmental pigmentation#GO:0048066;pigmentation#GO:0043473 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121838142|UniProtKB=A0ACM8G889 A0ACM8G889 LOC121838142 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8053291|UniProtKB=A0ACM8FDS2 A0ACM8FDS2 hts PTHR10672:SF44 ADDUCIN PROTEIN HU-LI TAI SHAO protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015 postsynaptic density#GO:0014069;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;asymmetric synapse#GO:0032279;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC8037640|UniProtKB=A0ACM8DWN8 A0ACM8DWN8 LOC8037640 PTHR10527:SF3 IMPORTIN BETA TRANSPORTIN-1 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;cellular localization#GO:0051641 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 IXOSC|EnsemblGenome=LOC8023132|UniProtKB=A0ACM8E778 A0ACM8E778 lqf PTHR12276:SF115 EPSIN/ENT-RELATED FI19443P1 clathrin binding#GO:0030276;binding#GO:0005488;phospholipid binding#GO:0005543;protein binding#GO:0005515;lipid binding#GO:0008289 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;endosome#GO:0005768;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;plasma membrane#GO:0005886;vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8029875|UniProtKB=A0ACM8E981 A0ACM8E981 MCTS1 PTHR22798:SF0 MCT-1 PROTEIN MALIGNANT T-CELL-AMPLIFIED SEQUENCE 1 translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 cytoplasmic translational initiation#GO:0002183;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120850871|UniProtKB=A0ACM8FBY0 A0ACM8FBY0 LOC120850871 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120848677|UniProtKB=A0ACM8FQK3 A0ACM8FQK3 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115329678|UniProtKB=A0ACM8EAF3 A0ACM8EAF3 LOC115329678 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115309988|UniProtKB=A0ACM8G1L9 A0ACM8G1L9 LOC115309988 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316708|UniProtKB=A0ACM8ENM7 A0ACM8ENM7 LOC115316708 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120844457|UniProtKB=A0ACM8EYU5 A0ACM8EYU5 LOC120844457 PTHR12203:SF126 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED PROTEIN O-GLUCOSYLTRANSFERASE 1 UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-xylosyltransferase activity#GO:0035252;UDP-glucosyltransferase activity#GO:0035251;xylosyltransferase activity#GO:0042285;glucosyltransferase activity#GO:0046527;pentosyltransferase activity#GO:0016763 primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of Notch signaling pathway#GO:0045747;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;protein metabolic process#GO:0019538;positive regulation of signaling#GO:0023056;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;carbohydrate derivative metabolic process#GO:1901135;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121833899|UniProtKB=A0ACM8FNP0 A0ACM8FNP0 PTHR15565:SF0 AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR PROTEIN AATF gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8037339|UniProtKB=A0ACM8G1S5 A0ACM8G1S5 LOC8037339 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8051690|UniProtKB=A0ACM8FBW5 A0ACM8FBW5 LOC8051690 PTHR36300:SF1 RAW, ISOFORM A RAW, ISOFORM A cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC120837846|UniProtKB=A0ACM8EHY4 A0ACM8EHY4 LOC120837846 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029620|UniProtKB=A0ACM8EBQ3 A0ACM8EBQ3 LOC8029620 PTHR11950:SF31 RUNT RELATED PROTEIN LOZENGE DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Runt transcription factor#PC00254;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8028459|UniProtKB=A0ACM8DGI3 A0ACM8DGI3 fd102C PTHR11829:SF416 FORKHEAD BOX PROTEIN FORKHEAD DOMAIN 102C sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC121047910|UniProtKB=A0ACM8FI38 A0ACM8FI38 LOC121047910 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041661|UniProtKB=A0ACM8EYH0 A0ACM8EYH0 LOC8041661 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC115325902|UniProtKB=A0ACM8FNV2 A0ACM8FNV2 LOC115325902 PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8028210|UniProtKB=A0ACM8E2P2 A0ACM8E2P2 knockout PTHR22437:SF0 WINGED HELIX DOMAIN-CONTAINING PROTEIN FI21431P1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115326359|UniProtKB=A0ACM8G1Z9 A0ACM8G1Z9 LOC115326359 PTHR11267:SF106 T-BOX PROTEIN-RELATED T-RELATED PROTEIN DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 IXOSC|EnsemblGenome=LOC120849963|UniProtKB=A0ACM8F7S0 A0ACM8F7S0 LOC120849963 PTHR11439:SF463 GAG-POL-RELATED RETROTRANSPOSON INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115332998|UniProtKB=A0ACM8EYK1 A0ACM8EYK1 LOC115332998 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324547|UniProtKB=A0ACM8E412 A0ACM8E412 Vps28 PTHR12937:SF0 VACUOLAR PROTEIN SORTING 28, ISOFORM 2 VPS28 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 28 HOMOLOG protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;cellular localization#GO:0051641;protein transport#GO:0015031;establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to vacuole#GO:0072665;localization#GO:0051179;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162 vesicle membrane#GO:0012506;cytosol#GO:0005829;membrane#GO:0016020;ESCRT I complex#GO:0000813;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120837818|UniProtKB=A0ACM8EIC7 A0ACM8EIC7 LOC120837818 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843975|UniProtKB=A0ACM8EXE1 A0ACM8EXE1 LOC120843975 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8051296|UniProtKB=A0ACM8DI82 A0ACM8DI82 ND-42 PTHR10513:SF15 DEOXYNUCLEOSIDE KINASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;deoxynucleoside kinase activity#GO:0019136;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121836055|UniProtKB=A0ACM8FXU8 A0ACM8FXU8 LOC121836055 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025078|UniProtKB=A0ACM8E0L0 A0ACM8E0L0 LOC8025078 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115333183|UniProtKB=A0ACM8EFN3 A0ACM8EFN3 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836013|UniProtKB=A0ACM8EJW4 A0ACM8EJW4 LOC120836013 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115327355|UniProtKB=A0ACM8EHM3 A0ACM8EHM3 LOC115327355 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121835896|UniProtKB=A0ACM8FW90 A0ACM8FW90 LOC121835896 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121835459|UniProtKB=A0ACM8FU74 A0ACM8FU74 LOC121835459 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8039533|UniProtKB=A0ACM8E334 A0ACM8E334 LOC8039533 PTHR21646:SF122 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8032083|UniProtKB=A0ACM8DJ53 A0ACM8DJ53 LOC8032083 PTHR10122:SF0 CYTOCHROME C OXIDASE SUBUNIT 5B, MITOCHONDRIAL CYTOCHROME C OXIDASE SUBUNIT 5B, ISOFORM A-RELATED generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;transporter complex#GO:1990351;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;oxidoreductase complex#GO:1990204;membrane#GO:0016020 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC120849594|UniProtKB=A0ACM8F908 A0ACM8F908 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893 nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8037676|UniProtKB=A0ACM8DMA0 A0ACM8DMA0 LOC8037676 PTHR11616:SF332 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120840949|UniProtKB=A0ACM8EQH6 A0ACM8EQH6 LOC120840949 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120846236|UniProtKB=A0ACM8F1K2 A0ACM8F1K2 LOC120846236 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115325709|UniProtKB=A0ACM8FEE6 A0ACM8FEE6 LOC115325709 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8053566|UniProtKB=A0ACM8E9V7 A0ACM8E9V7 foxo PTHR45767:SF2 FORKHEAD BOX PROTEIN O FORKHEAD BOX PROTEIN O RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>FKHR#P00898 IXOSC|EnsemblGenome=LOC8032675|UniProtKB=A0ACM8G611 A0ACM8G611 LOC8032675 PTHR45718:SF9 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS SUBFAMILY NOT NAMED gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8023085|UniProtKB=A0ACM8EIM6 A0ACM8EIM6 LOC8023085 PTHR11596:SF96 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120845762|UniProtKB=A0ACM8FGR8 A0ACM8FGR8 LOC120845762 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8053097|UniProtKB=A0ACM8F1A8 A0ACM8F1A8 LOC8053097 PTHR15711:SF62 RAP GTPASE-ACTIVATING PROTEIN GTPASE-ACTIVATING RAP_RAN-GAP DOMAIN-LIKE PROTEIN 3 enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1GAP#P00737 IXOSC|EnsemblGenome=LOC8040750|UniProtKB=A0ACM8EUP3 A0ACM8EUP3 LOC8040750 PTHR11010:SF128 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120849513|UniProtKB=A0ACM8FIQ3 A0ACM8FIQ3 LOC121836090 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325874|UniProtKB=A0ACM8E673 A0ACM8E673 LOC115325874 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8038635|UniProtKB=A0ACM8EF66 A0ACM8EF66 alpha-Man-Ia PTHR11742:SF6 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE IA-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8029785|UniProtKB=A0ACM8G6M5 A0ACM8G6M5 LOC8029785 PTHR21538:SF23 ANILLIN/RHOTEKIN RTKN ANILLIN cell cycle process#GO:0022402;cell division#GO:0051301;cellular component organization#GO:0016043;cell cycle#GO:0007049;actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;septin ring organization#GO:0031106;cytoskeleton-dependent cytokinesis#GO:0061640;cortical actin cytoskeleton organization#GO:0030866;cellular process#GO:0009987;actomyosin contractile ring assembly#GO:0000915;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;septin cytoskeleton organization#GO:0032185;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840 cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cell periphery#GO:0071944;membraneless organelle#GO:0043228;actomyosin contractile ring#GO:0005826;cytoskeleton#GO:0005856;contractile ring#GO:0070938;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC8042268|UniProtKB=A0ACM8E7J0 A0ACM8E7J0 LOC8042268 PTHR21559:SF21 DYSTROGLYCAN-RELATED DYSTROGLYCAN 1 cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;morphogenesis of an epithelium#GO:0002009;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;tissue morphogenesis#GO:0048729;system development#GO:0048731;muscle structure development#GO:0061061;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelium development#GO:0060429;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;sarcolemma#GO:0042383 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC121838303|UniProtKB=A0ACM8G7K4 A0ACM8G7K4 LOC121838303 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC120850738|UniProtKB=A0ACM8FAZ9 A0ACM8FAZ9 LOC120850738 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319716|UniProtKB=A0ACM8G4Y4 A0ACM8G4Y4 LOC115319716 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8031491|UniProtKB=A0ACM8DIB2 A0ACM8DIB2 LOC8031491 PTHR12794:SF0 GEMIN2 GEM-ASSOCIATED PROTEIN 2 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;SMN complex#GO:0032797;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120845935|UniProtKB=A0ACM8G6H1 A0ACM8G6H1 LOC120845935 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120851088|UniProtKB=A0ACM8FBE6 A0ACM8FBE6 LOC120851088 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053504|UniProtKB=A0ACM8EY46 A0ACM8EY46 LOC8053504 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8041281|UniProtKB=A0ACM8ECN9 A0ACM8ECN9 LOC8041281 PTHR44156:SF32 SUPERNUMERARY LIMBS, ISOFORM B-RELATED F-BOX_WD REPEAT-CONTAINING PROTEIN 7-RELATED Notch signaling pathway#P00045>Sel 10#P01102 IXOSC|EnsemblGenome=LOC8025014|UniProtKB=A0ACM8G633 A0ACM8G633 LOC8025014 PTHR10574:SF365 NETRIN/LAMININ-RELATED NETRIN-A-RELATED neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;anatomical structure development#GO:0048856;system development#GO:0048731;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;neuron projection development#GO:0031175;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;dendrite development#GO:0016358;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 extracellular matrix protein#PC00102 Axon guidance mediated by Slit/Robo#P00008>Netrin#P00344;Axon guidance mediated by netrin#P00009>Netrin#P00357 IXOSC|EnsemblGenome=LOC8030267|UniProtKB=A0ACM8DGJ3 A0ACM8DGJ3 Adi1 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115320902|UniProtKB=A0ACM8FLR0 A0ACM8FLR0 LOC115320902 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8031738|UniProtKB=A0ACM8F4W3 A0ACM8F4W3 LOC8031738 PTHR46708:SF2 TENASCIN FIBRONECTIN-LIKE extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC115318873|UniProtKB=A0ACM8G3N9 A0ACM8G3N9 LOC115318873 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318894|UniProtKB=A0ACM8DYB2 A0ACM8DYB2 LOC115318894 PTHR48112:SF31 HIGH MOBILITY GROUP PROTEIN DSP1 HMG BOX DOMAIN-CONTAINING PROTEIN cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 IXOSC|EnsemblGenome=LOC115330900|UniProtKB=A0ACM8F7R8 A0ACM8F7R8 LOC115330900 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8024951|UniProtKB=A0ACM8FJL7 A0ACM8FJL7 LOC8024951 PTHR23116:SF40 PDZ DOMAIN CONTAINING WHIRLIN AND HARMONIN-RELATED PDZ DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;stereocilium#GO:0032420;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;membrane-bounded organelle#GO:0043227;cluster of actin-based cell projections#GO:0098862;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cilium#GO:0005929 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120837761|UniProtKB=A0ACM8EI67 A0ACM8EI67 MESR3 PTHR20338:SF7 NUCLEAR RESPIRATORY FACTOR 1 MISEXPRESSION SUPPRESSOR OF RAS 3, ISOFORM B transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121833814|UniProtKB=A0ACM8FMU7 A0ACM8FMU7 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8025922|UniProtKB=A0ACM8FL91 A0ACM8FL91 LOC8025922 PTHR45080:SF49 CONTACTIN 5 FOLLISTATIN-RELATED PROTEIN 5 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 synapse organization#GO:0050808;cell adhesion#GO:0007155;cellular component organization or biogenesis#GO:0071840;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;axon#GO:0030424 IXOSC|EnsemblGenome=LOC8042174|UniProtKB=A0ACM8DYZ2 A0ACM8DYZ2 LOC8042174 PTHR11915:SF455 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN ALPHA-ACTININ, SARCOMERIC-RELATED binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 organelle organization#GO:0006996;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856 cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;contractile muscle fiber#GO:0043292;cell periphery#GO:0071944;Z disc#GO:0030018;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;I band#GO:0031674;cytoskeleton#GO:0005856;cell junction#GO:0030054;sarcomere#GO:0030017;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>alpha actinin#P00928 IXOSC|EnsemblGenome=LOC120842768|UniProtKB=A0ACM8EUF0 A0ACM8EUF0 LOC120842768 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED IXOSC|EnsemblGenome=LOC115319900|UniProtKB=A0ACM8E0L7 A0ACM8E0L7 LOC115319900 PTHR45715:SF23 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED ATPASE H+ TRANSPORTING V1 SUBUNIT E1 monoatomic cation transmembrane transporter activity#GO:0008324;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495 IXOSC|EnsemblGenome=LOC120850317|UniProtKB=A0ACM8F8I8 A0ACM8F8I8 LOC120850317 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC120846701|UniProtKB=A0ACM8F270 A0ACM8F270 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC121835901|UniProtKB=A0ACM8FXF1 A0ACM8FXF1 LOC121835901 PTHR23080:SF153 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842849|UniProtKB=A0ACM8EUK9 A0ACM8EUK9 PTHR24241:SF117 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE S RECEPTOR-LIKE signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115315187|UniProtKB=A0ACM8G842 A0ACM8G842 LOC115315187 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8037657|UniProtKB=A0ACM8DM69 A0ACM8DM69 LOC8037657 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8037495|UniProtKB=A0ACM8DRR3 A0ACM8DRR3 LOC8037495 PTHR25462:SF311 BONUS, ISOFORM C-RELATED PROTEIN MEIOTIC P26 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8026562|UniProtKB=A0ACM8FAM2 A0ACM8FAM2 LOC8026562 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121047082|UniProtKB=A0ACM8FGE8 A0ACM8FGE8 LOC121047082 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8037048|UniProtKB=A0ACM8DVC1 A0ACM8DVC1 twz PTHR14499:SF67 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING BTB_POZ DOMAIN-CONTAINING PROTEIN TIWAZ transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8052379|UniProtKB=A0ACM8DM40 A0ACM8DM40 LOC8052379 PTHR10438:SF475 THIOREDOXIN THIOREDOXIN oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular homeostasis#GO:0019725;homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 IXOSC|EnsemblGenome=LOC121837271|UniProtKB=A0ACM8G310 A0ACM8G310 LOC121837271 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC121835635|UniProtKB=A0ACM8FV53 A0ACM8FV53 LOC121835635 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121838521|UniProtKB=A0ACM8G952 A0ACM8G952 LOC121838521 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120849202|UniProtKB=A0ACM8F7N3 A0ACM8F7N3 LOC120849202 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8034217|UniProtKB=A0ACM8DJ32 A0ACM8DJ32 LOC8034217 PTHR10807:SF133 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121835282|UniProtKB=A0ACM8FTP2 A0ACM8FTP2 LOC121835282 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329251|UniProtKB=A0ACM8G0Z2 A0ACM8G0Z2 LOC115329251 PTHR22625:SF61 PLEXIN HEPATOCYTE GROWTH FACTOR RECEPTOR transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;synapse assembly#GO:0007416;cell junction organization#GO:0034330;signaling#GO:0023052;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of cell migration#GO:0030334;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;cellular component biogenesis#GO:0044085;signal transduction#GO:0007165;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8036053|UniProtKB=A0ACM8E1T5 A0ACM8E1T5 PTHR22730:SF1 PROMININ PROM PROTEIN PROMININ-LIKE PROTEIN cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cellular process#GO:0009987 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;microvillus#GO:0005902;actin-based cell projection#GO:0098858;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC120841314|UniProtKB=A0ACM8G3D3 A0ACM8G3D3 LOC120841314 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8024943|UniProtKB=A0ACM8DIU6 A0ACM8DIU6 LOC8024943 PTHR16465:SF0 NUCLEASE-RELATED ZINC FINGER MATRIN-TYPE PROTEIN 5 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8043238|UniProtKB=A0ACM8E9S2 A0ACM8E9S2 E(bx) PTHR45975:SF2 NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF IXOSC|EnsemblGenome=LOC115313962|UniProtKB=A0ACM8FYD5 A0ACM8FYD5 LOC115313962 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8024688|UniProtKB=A0ACM8F1P6 A0ACM8F1P6 LOC8024688 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC115329516|UniProtKB=A0ACM8E9L8 A0ACM8E9L8 LOC115329516 PTHR28314:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 29 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC121833217|UniProtKB=A0ACM8FJY9 A0ACM8FJY9 LOC121833217 PTHR16120:SF0 AP-5 COMPLEX SUBUNIT SIGMA-1 AP-5 COMPLEX SUBUNIT SIGMA-1 establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cytosol#GO:0005829;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;vacuole#GO:0005773;cytoplasm#GO:0005737;lytic vacuole#GO:0000323;AP-type membrane coat adaptor complex#GO:0030119;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 IXOSC|EnsemblGenome=LOC115316687|UniProtKB=A0ACM8G8K8 A0ACM8G8K8 LOC115316687 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 IXOSC|EnsemblGenome=LOC8050474|UniProtKB=A0ACM8DLE3 A0ACM8DLE3 LOC8050474 PTHR35154:SF3 GBP PROTEIN GBP PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8051475|UniProtKB=A0ACM8EBR6 A0ACM8EBR6 LOC8051475 PTHR19290:SF162 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR AMOS-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8040870|UniProtKB=A0ACM8G2S1 A0ACM8G2S1 LOC8040870 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8035146|UniProtKB=A0ACM8E5Q0 A0ACM8E5Q0 LOC8035146 PTHR10857:SF106 COPINE NICOTINIC RECEPTOR-ASSOCIATED PROTEIN 1 binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289 response to chemical#GO:0042221;response to calcium ion#GO:0051592;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to metal ion#GO:0010038;cellular response to chemical stimulus#GO:0070887 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC8052278|UniProtKB=A0ACM8DWQ1 A0ACM8DWQ1 LOC8052278 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC120841582|UniProtKB=A0ACM8ET09 A0ACM8ET09 LOC120841582 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040542|UniProtKB=A0ACM8DXH4 A0ACM8DXH4 LOC8040542 PTHR45644:SF88 AAA ATPASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12920)-RELATED-RELATED FI08533P-RELATED localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;localization within membrane#GO:0051668;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC8050793|UniProtKB=A0ACM8DPQ0 A0ACM8DPQ0 LOC8050793 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8034907|UniProtKB=A0ACM8DJM5 A0ACM8DJM5 LOC8034907 PTHR11699:SF315 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity#GO:0016491;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC115324235|UniProtKB=A0ACM8EW05 A0ACM8EW05 LOC115324235 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120844326|UniProtKB=A0ACM8EYD9 A0ACM8EYD9 LOC120844326 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842009|UniProtKB=A0ACM8ESV3 A0ACM8ESV3 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115310350|UniProtKB=A0ACM8FP03 A0ACM8FP03 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8030237|UniProtKB=A0ACM8E362 A0ACM8E362 LOC8030237 PTHR21308:SF1 PHYTANOYL-COA ALPHA-HYDROXYLASE PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034863|UniProtKB=A0ACM8DJK0 A0ACM8DJK0 LOC8034863 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;response to heat#GO:0009408;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein folding#GO:0006457;response to stimulus#GO:0050896;protein refolding#GO:0042026;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC115327181|UniProtKB=A0ACM8E7D2 A0ACM8E7D2 LOC115327181 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8030480|UniProtKB=A0ACM8FHS7 A0ACM8FHS7 LOC8030480 PTHR19300:SF66 BETA-1,4-GALACTOSYLTRANSFERASE BETA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE A glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120848343|UniProtKB=A0ACM8F6L5 A0ACM8F6L5 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039811|UniProtKB=A0ACM8DKG1 A0ACM8DKG1 MrgBP PTHR13581:SF5 MRG-BINDING PROTEIN MRG_MORF4L-BINDING PROTEIN regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8026171|UniProtKB=A0ACM8FEN5 A0ACM8FEN5 LOC8026171 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8034496|UniProtKB=A0ACM8DXN0 A0ACM8DXN0 LOC8034496 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8040565|UniProtKB=A0ACM8DT47 A0ACM8DT47 LOC8040565 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824 nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;purine-containing compound metabolic process#GO:0072521;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043949|UniProtKB=A0ACM8DYG0 A0ACM8DYG0 PTHR20849:SF2 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN MEXTLI EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN MEXTLI translation factor activity#GO:0180051;binding#GO:0005488;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;translation initiation factor binding#GO:0031369 positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8036230|UniProtKB=A0ACM8F8N3 A0ACM8F8N3 LOC8036230 PTHR13142:SF1 INNER CENTROMERE PROTEIN INNER CENTROMERE PROTEIN intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;midbody#GO:0030496;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8034161|UniProtKB=A0ACM8DRF9 A0ACM8DRF9 LOC8034161 PTHR21522:SF62 PROTON CHANNEL OTOP OTOPETRIN-LIKE A, ISOFORM C proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8038746|UniProtKB=A0ACM8E699 A0ACM8E699 LOC8038746 PTHR11960:SF66 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 translation initiation factor activity#GO:0003743;RNA binding#GO:0003723;translation factor activity#GO:0180051;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 IXOSC|EnsemblGenome=LOC115333007|UniProtKB=A0ACM8EDX0 A0ACM8EDX0 LOC115333007 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121837726|UniProtKB=A0ACM8G4W5 A0ACM8G4W5 LOC121837726 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120840995|UniProtKB=A0ACM8ERQ6 A0ACM8ERQ6 LOC120840995 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115328136|UniProtKB=A0ACM8E8E6 A0ACM8E8E6 LOC115328136 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8031827|UniProtKB=A0ACM8FKE7 A0ACM8FKE7 LOC8031827 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoatomic cation transmembrane transporter activity#GO:0008324 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC115324240|UniProtKB=A0ACM8E3Q3 A0ACM8E3Q3 IscU PTHR10093:SF8 IRON-SULFUR CLUSTER ASSEMBLY ENZYME NIFU HOMOLOG IRON-SULFUR CLUSTER ASSEMBLY ENZYME ISCU iron-sulfur cluster binding#GO:0051536;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115314398|UniProtKB=A0ACM8DTN3 A0ACM8DTN3 LOC115314398 PTHR12665:SF7 ORMDL PROTEINS ORM1-LIKE PROTEIN primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;cellular process#GO:0009987;homeostatic process#GO:0042592;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;ceramide metabolic process#GO:0006672;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 IXOSC|EnsemblGenome=LOC120842054|UniProtKB=A0ACM8ESZ6 A0ACM8ESZ6 LOC120842054 PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120841741|UniProtKB=A0ACM8ESF0 A0ACM8ESF0 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841416|UniProtKB=A0ACM8G8X7 A0ACM8G8X7 LOC120841416 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115311019|UniProtKB=A0ACM8G099 A0ACM8G099 LOC115311019 PTHR48575:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025981|UniProtKB=A0ACM8EBE1 A0ACM8EBE1 LOC8025981 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8051264|UniProtKB=A0ACM8FS94 A0ACM8FS94 LOC8051264 PTHR24264:SF91 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115319275|UniProtKB=A0ACM8DZG1 A0ACM8DZG1 LOC115319275 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842310|UniProtKB=A0ACM8ET96 A0ACM8ET96 LOC120842310 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 IXOSC|EnsemblGenome=LOC121834297|UniProtKB=A0ACM8FPJ3 A0ACM8FPJ3 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051910|UniProtKB=A0ACM8DTS9 A0ACM8DTS9 LOC8051910 PTHR20932:SF13 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN LD36653P IXOSC|EnsemblGenome=LOC121048656|UniProtKB=A0ACM8G3Q8 A0ACM8G3Q8 LOC121048656 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8053876|UniProtKB=A0ACM8DNZ3 A0ACM8DNZ3 LOC8053876 PTHR23123:SF21 PHD/F-BOX CONTAINING PROTEIN JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 1 histone modifying activity#GO:0140993;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121833683|UniProtKB=A0ACM8FM77 A0ACM8FM77 LOC121833683 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115328225|UniProtKB=A0ACM8F8E4 A0ACM8F8E4 LOC115328225 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE-LIKE transferase#PC00220 IXOSC|EnsemblGenome=LOC115328226|UniProtKB=A0ACM8E8J6 A0ACM8E8J6 LOC115328226 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8050624|UniProtKB=A0ACM8G2U2 A0ACM8G2U2 LOC8050624 PTHR47767:SF1 ADHESION G PROTEIN-COUPLED RECEPTOR G7 ADHESION G PROTEIN-COUPLED RECEPTOR G7 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115330332|UniProtKB=A0ACM8EYY7 A0ACM8EYY7 LOC115330332 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030633|UniProtKB=A0ACM8EVF7 A0ACM8EVF7 LOC8030633 PTHR28599:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 12 SMALL INTEGRAL MEMBRANE PROTEIN 12 IXOSC|EnsemblGenome=LOC120839011|UniProtKB=A0ACM8ELA4 A0ACM8ELA4 LOC120839011 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8030751|UniProtKB=A0ACM8E758 A0ACM8E758 SCAR PTHR12902:SF39 WASP-1 WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY MEMBER protein binding#GO:0005515;protein-containing complex binding#GO:0044877;protein kinase A binding#GO:0051018;binding#GO:0005488;protein kinase A regulatory subunit binding#GO:0034237 regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cellular component organization#GO:0016043;positive regulation of organelle organization#GO:0010638;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of actin nucleation#GO:0051125 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC121835205|UniProtKB=A0ACM8FTV3 A0ACM8FTV3 LOC121835205 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 IXOSC|EnsemblGenome=LOC120850753|UniProtKB=A0ACM8FBN6 A0ACM8FBN6 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8042201|UniProtKB=A0ACM8FJM5 A0ACM8FJM5 LOC8042201 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121833391|UniProtKB=A0ACM8FJE8 A0ACM8FJE8 LOC121833391 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8039417|UniProtKB=A0ACM8E144 A0ACM8E144 LOC8039417 PTHR12352:SF25 SECRETED MODULAR CALCIUM-BINDING PROTEIN TESTICAN-1 establishment of protein localization#GO:0045184;localization#GO:0051179;establishment of localization#GO:0051234;establishment of protein localization to extracellular region#GO:0035592 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8038205|UniProtKB=A0ACM8DGP0 A0ACM8DGP0 LOC8038205 PTHR13390:SF0 LIPASE LIPID DROPLET-ASSOCIATED HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular component organization#GO:0016043;lipid droplet organization#GO:0034389;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8026997|UniProtKB=A0ACM8EBF9 A0ACM8EBF9 PTHR11679:SF91 VESICLE PROTEIN SORTING-ASSOCIATED PROTEIN ROP syntaxin binding#GO:0019905;protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 vesicle-mediated transport in synapse#GO:0099003;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;neurotransmitter transport#GO:0006836;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular localization#GO:0051641;protein transport#GO:0015031;secretion by cell#GO:0032940;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;signaling#GO:0023052;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;calcium-ion regulated exocytosis#GO:0017156;intracellular transport#GO:0046907;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;neurotransmitter secretion#GO:0007269;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268 membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8036003|UniProtKB=A0ACM8EZF1 A0ACM8EZF1 LOC8036003 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837488|UniProtKB=A0ACM8EHL7 A0ACM8EHL7 LOC120837488 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC115332188|UniProtKB=A0ACM8ED70 A0ACM8ED70 LOC115332188 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121834216|UniProtKB=A0ACM8FQG3 A0ACM8FQG3 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041822|UniProtKB=A0ACM8DS30 A0ACM8DS30 LOC8041822 PTHR12999:SF26 ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 ZRANB2-RELATED ZINC FINGER RAN-BINDING DOMAIN-CONTAINING PROTEIN 2 lipid binding#GO:0008289;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;lipopolysaccharide binding#GO:0001530 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120850251|UniProtKB=A0ACM8F8E1 A0ACM8F8E1 LOC120850251 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120846778|UniProtKB=A0ACM8F389 A0ACM8F389 LOC120846778 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025333|UniProtKB=A0ACM8E5P0 A0ACM8E5P0 LOC8025333 PTHR14167:SF76 SH3 DOMAIN-CONTAINING ENDOPHILIN B, ISOFORM A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115321041|UniProtKB=A0ACM8E1G3 A0ACM8E1G3 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115319055|UniProtKB=A0ACM8F4D0 A0ACM8F4D0 LOC115319055 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8043103|UniProtKB=A0ACM8DMY9 A0ACM8DMY9 ash2 PTHR10598:SF0 SET1/ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 SET1_ASH2 HISTONE METHYLTRANSFERASE COMPLEX SUBUNIT ASH2 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690 protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8030153|UniProtKB=A0ACM8DRW7 A0ACM8DRW7 LOC8030153 PTHR21192:SF2 NUCLEAR PROTEIN E3-3 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3 cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743 IXOSC|EnsemblGenome=LOC120840968|UniProtKB=A0ACM8EQY2 A0ACM8EQY2 LOC120840968 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120849036|UniProtKB=A0ACM8F6Y4 A0ACM8F6Y4 LOC121837540 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8035902|UniProtKB=A0ACM8E6G6 A0ACM8E6G6 LOC8035902 PTHR11098:SF1 NICOTINATE PHOSPHORIBOSYLTRANSFERASE NICOTINATE PHOSPHORIBOSYLTRANSFERASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;pyridine-containing compound metabolic process#GO:0072524 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8026302|UniProtKB=A0ACM8DHL0 A0ACM8DHL0 mAChR-A PTHR24247:SF265 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR DM1 G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;acetylcholine receptor activity#GO:0015464;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960 trans-synaptic signaling#GO:0099537;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;chemical synaptic transmission#GO:0007268;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;synaptic signaling#GO:0099536;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular response to nitrogen compound#GO:1901699;acetylcholine receptor signaling pathway#GO:0095500;response to chemical#GO:0042221;biological regulation#GO:0065007;cell-cell signaling#GO:0007267 dendrite#GO:0030425;dendritic tree#GO:0097447;cell junction#GO:0030054;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730 IXOSC|EnsemblGenome=LOC8033993|UniProtKB=A0ACM8E1B9 A0ACM8E1B9 red PTHR20932:SF8 LYSM AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN AND PUTATIVE PEPTIDOGLYCAN-BINDING DOMAIN-CONTAINING PROTEIN 1-RELATED IXOSC|EnsemblGenome=LOC8037810|UniProtKB=A0ACM8DI94 A0ACM8DI94 LOC8037810 PTHR23235:SF120 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUPPEL-LIKE FACTOR 15 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121047313|UniProtKB=A0ACM8FGX3 A0ACM8FGX3 LOC121047313 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8037792|UniProtKB=A0ACM8ECT4 A0ACM8ECT4 LOC8037792 PTHR22891:SF198 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-1 RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;single-stranded RNA binding#GO:0003727;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120838185|UniProtKB=A0ACM8EJC0 A0ACM8EJC0 LOC120838185 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053446|UniProtKB=A0ACM8FCZ2 A0ACM8FCZ2 PTHR13043:SF1 EXOCYST COMPLEX COMPONENT SEC5 EXOCYST COMPLEX COMPONENT 2 secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;exocyst#GO:0000145;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 Ras Pathway#P04393>Sec5#P04545 IXOSC|EnsemblGenome=LOC115329802|UniProtKB=A0ACM8ES56 A0ACM8ES56 LOC115329802 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121833545|UniProtKB=A0ACM8FKB7 A0ACM8FKB7 LOC121833545 PTHR43831:SF1 ISOBUTYRYL-COA DEHYDROGENASE ISOBUTYRYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121837957|UniProtKB=A0ACM8G6Y8 A0ACM8G6Y8 LOC121837957 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120838967|UniProtKB=A0ACM8EM12 A0ACM8EM12 LOC120838967 PTHR24365:SF555 TOLL-LIKE RECEPTOR MSTPROX-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8027114|UniProtKB=A0ACM8EFV6 A0ACM8EFV6 Ptp99A PTHR19134:SF577 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE 99A catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;cell communication#GO:0007154;neuron development#GO:0048666;system development#GO:0048731 protein phosphatase#PC00195;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115329998|UniProtKB=A0ACM8F934 A0ACM8F934 LOC115329998 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043913|UniProtKB=A0ACM8EA34 A0ACM8EA34 Polr3F PTHR12780:SF1 RNA POLYMERASE III DNA DIRECTED , 39KD SUBUNIT-RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC6 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115327911|UniProtKB=A0ACM8FY73 A0ACM8FY73 LOC115327911 PTHR11426:SF263 HISTONE H3 HISTONE H3.X-RELATED cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular process#GO:0009987;kinetochore organization#GO:0051383;localization#GO:0051179;organelle fission#GO:0048285;organelle assembly#GO:0070925;organelle localization#GO:0051640;nuclear division#GO:0000280;kinetochore assembly#GO:0051382;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8026316|UniProtKB=A0ACM8ET10 A0ACM8ET10 LOC8026316 PTHR24416:SF489 TYROSINE-PROTEIN KINASE RECEPTOR PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8039496|UniProtKB=A0ACM8FYE7 A0ACM8FYE7 LOC8039496 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053373|UniProtKB=A0ACM8EZL2 A0ACM8EZL2 LOC8053373 PTHR18884:SF137 SEPTIN SEPTIN-7 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;macromolecule localization#GO:0033036;cell cycle#GO:0007049 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8024576|UniProtKB=A0ACM8G716 A0ACM8G716 LOC8024576 PTHR24373:SF406 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TARTAN, ISOFORM B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121833134|UniProtKB=A0ACM8FIC8 A0ACM8FIC8 LOC121833134 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC121832875|UniProtKB=A0ACM8FBA1 A0ACM8FBA1 LOC121832875 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121047809|UniProtKB=A0ACM8G3F6 A0ACM8G3F6 LOC121047809 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8030973|UniProtKB=A0ACM8G7S6 A0ACM8G7S6 Mct1 PTHR11360:SF325 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120838642|UniProtKB=A0ACM8FVM8 A0ACM8FVM8 LOC120838642 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 IXOSC|EnsemblGenome=LOC8031330|UniProtKB=A0ACM8DUM6 A0ACM8DUM6 Fbxo42 PTHR46432:SF1 F-BOX ONLY PROTEIN 42 F-BOX ONLY PROTEIN 42 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461 IXOSC|EnsemblGenome=LOC120843232|UniProtKB=A0ACM8EVG1 A0ACM8EVG1 LOC120843232 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050818|UniProtKB=A0ACM8G1K5 A0ACM8G1K5 LOC8050818 PTHR43447:SF61 ALPHA-AMYLASE ALPHA-AMYLASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 amylase#PC00048 IXOSC|EnsemblGenome=LOC115325642|UniProtKB=A0ACM8E5R9 A0ACM8E5R9 Duba PTHR12419:SF122 OTU DOMAIN CONTAINING PROTEIN OTU DOMAIN-CONTAINING PROTEIN 5 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 positive regulation of TORC1 signaling#GO:1904263;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;positive regulation of response to stimulus#GO:0048584;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;negative regulation of cell communication#GO:0010648 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC120849384|UniProtKB=A0ACM8F6Q0 A0ACM8F6Q0 LOC120849384 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115310031|UniProtKB=A0ACM8ER62 A0ACM8ER62 LOC115310031 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8053753|UniProtKB=A0ACM8FIT0 A0ACM8FIT0 LOC8053753 PTHR37558:SF1 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN TRICHOHYALIN IXOSC|EnsemblGenome=LOC115309371|UniProtKB=A0ACM8DNT4 A0ACM8DNT4 LOC115309371 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8039436|UniProtKB=A0ACM8EDA4 A0ACM8EDA4 emei PTHR13624:SF6 RE42071P EMEI IXOSC|EnsemblGenome=LOC8052973|UniProtKB=A0ACM8FKV9 A0ACM8FKV9 LOC8052973 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 IXOSC|EnsemblGenome=LOC115308325|UniProtKB=A0ACM8DMA2 A0ACM8DMA2 mRRF2 PTHR43261:SF9 TRANSLATION ELONGATION FACTOR G-RELATED RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 translation#GO:0006412;mitochondrial gene expression#GO:0140053;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467 translational protein#PC00263;translation factor#PC00223;translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC8033203|UniProtKB=A0ACM8EAY5 A0ACM8EAY5 LOC8033203 PTHR12701:SF20 BCR-ASSOCIATED PROTEIN, BAP ENDOPLASMIC RETICULUM TRANSMEMBRANE PROTEIN ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 positive regulation of metabolic process#GO:0009893;protein transport#GO:0015031;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;establishment of protein localization#GO:0045184;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;localization#GO:0051179;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;ERAD pathway#GO:0036503;regulation of protein catabolic process#GO:0042176;response to endoplasmic reticulum stress#GO:0034976;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;regulation of catabolic process#GO:0009894;transport#GO:0006810;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;macromolecule localization#GO:0033036;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121835344|UniProtKB=A0ACM8FU58 A0ACM8FU58 LOC121835344 PTHR12687:SF4 NUCLEOLAR COMPLEX 2 AND RAD4-RELATED NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;90S preribosome#GO:0030686;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8028674|UniProtKB=A0ACM8E8K2 A0ACM8E8K2 LOC8028674 PTHR12459:SF27 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN 135 IXOSC|EnsemblGenome=LOC8037688|UniProtKB=A0ACM8DTA3 A0ACM8DTA3 LOC8037688 PTHR44329:SF325 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED RAF HOMOLOG SERINE_THREONINE-PROTEIN KINASE RAF catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;MAP kinase kinase kinase activity#GO:0004709 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;ERK1 and ERK2 cascade#GO:0070371;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>Raf#P01161;VEGF signaling pathway#P00056>Raf#P01417;Angiogenesis#P00005>Raf#P00243;Endothelin signaling pathway#P00019>Raf-1#P00587;EGF receptor signaling pathway#P00018>Raf-1#P00560;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Raf-1#P00843 IXOSC|EnsemblGenome=LOC8035084|UniProtKB=A0ACM8E8B6 A0ACM8E8B6 Rab4 PTHR47979:SF139 DRAB11-RELATED SMALL MONOMERIC GTPASE heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168 transport#GO:0006810;regulation of endocytosis#GO:0030100;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;vesicle-mediated transport#GO:0016192;regulation of cellular component organization#GO:0051128 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC8025944|UniProtKB=A0ACM8FG80 A0ACM8FG80 LOC8025944 PTHR12587:SF20 LAR INTERACTING PROTEIN LIP -RELATED PROTEIN LIPRIN-ALPHA, ISOFORM E structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 presynapse#GO:0098793;cellular anatomical structure#GO:0110165;synapse#GO:0045202;presynaptic active zone#GO:0048786;cell junction#GO:0030054 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120844229|UniProtKB=A0ACM8FJI3 A0ACM8FJI3 LOC120844229 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC115329942|UniProtKB=A0ACM8EBL0 A0ACM8EBL0 LOC115329942 PTHR37457:SF3 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED TRNA SELENOCYSTEINE-ASSOCIATED PROTEIN 1 IXOSC|EnsemblGenome=LOC8038664|UniProtKB=A0ACM8ECS3 A0ACM8ECS3 LOC8038664 PTHR10559:SF18 TRANSCOBALAMIN-1/GASTRIC INTRINSIC FACTOR TRANSCOBALAMIN II tetrapyrrole binding#GO:0046906;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;binding#GO:0005488 establishment of localization#GO:0051234;vitamin transport#GO:0051180;localization#GO:0051179;transport#GO:0006810;nitrogen compound transport#GO:0071705 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC115313362|UniProtKB=A0ACM8DT14 A0ACM8DT14 LOC115313362 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120835988|UniProtKB=A0ACM8F485 A0ACM8F485 LOC120835988 PTHR19303:SF57 TRANSPOSON POGO TRANSPOSABLE ELEMENT WITH KRAB DOMAIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8023082|UniProtKB=A0ACM8DMY8 A0ACM8DMY8 LOC8023082 PTHR24348:SF65 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK3 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;piecemeal microautophagy of the nucleus#GO:0034727;response to stimulus#GO:0050896;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;response to starvation#GO:0042594;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of catabolic process#GO:0009894;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;biological regulation#GO:0065007;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;reticulophagy#GO:0061709;regulation of metabolic process#GO:0019222;response to stress#GO:0006950 phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120843815|UniProtKB=A0ACM8EXZ6 A0ACM8EXZ6 LOC120843815 PTHR23080:SF153 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027218|UniProtKB=A0ACM8DIU8 A0ACM8DIU8 LOC8027218 PTHR23322:SF107 FAS-ASSOCIATED PROTEIN CASPAR, ISOFORM A protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 FAS signaling pathway#P00020>FAF1#P00609 IXOSC|EnsemblGenome=LOC115329106|UniProtKB=A0ACM8E937 A0ACM8E937 LOC115329106 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030066|UniProtKB=A0ACM8FMK1 A0ACM8FMK1 LOC8030066 PTHR24247:SF249 5-HYDROXYTRYPTAMINE RECEPTOR OCTOPAMINE RECEPTOR OAMB G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154 dendritic tree#GO:0097447;dendrite#GO:0030425;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115331978|UniProtKB=A0ACM8ET41 A0ACM8ET41 LOC115331978 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120841666|UniProtKB=A0ACM8FF28 A0ACM8FF28 LOC120841666 PTHR47969:SF41 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED KINESIN-LIKE PROTEIN KIF21A ISOFORM X1 cytoskeletal motor activity#GO:0003774;microtubule motor activity#GO:0003777;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 cellular process#GO:0009987;organelle organization#GO:0006996;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cell cycle process#GO:0022402;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226 microtubule binding motor protein#PC00156;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC115312649|UniProtKB=A0ACM8DS10 A0ACM8DS10 LOC115312649 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115312639|UniProtKB=A0ACM8FQY9 A0ACM8FQY9 LOC115312639 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC120839327|UniProtKB=A0ACM8EL47 A0ACM8EL47 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115318745|UniProtKB=A0ACM8DYW6 A0ACM8DYW6 LOC115318745 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053262|UniProtKB=A0ACM8DZ87 A0ACM8DZ87 LOC8053262 PTHR19143:SF444 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FICOLIN-3 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8036104|UniProtKB=A0ACM8DN36 A0ACM8DN36 Vps16A PTHR12811:SF3 VACUOLAR PROTEIN SORTING VPS16 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 endosomal transport#GO:0016197;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;vacuole fusion, non-autophagic#GO:0042144;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;vacuole organization#GO:0007033;localization#GO:0051179;cellular localization#GO:0051641;vacuole fusion#GO:0097576;cellular component organization#GO:0016043 membrane#GO:0016020;lysosomal membrane#GO:0005765;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle tethering complex#GO:0099023;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115325007|UniProtKB=A0ACM8E4H3 A0ACM8E4H3 lin PTHR16057:SF1 WINS1, 2 PROTEIN PROTEIN LINES HOMOLOG 1 IXOSC|EnsemblGenome=LOC120837732|UniProtKB=A0ACM8EIV5 A0ACM8EIV5 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8053035|UniProtKB=A0ACM8DR97 A0ACM8DR97 Bre1 PTHR23163:SF0 RING FINGER PROTEIN-RELATED E3 UBIQUITIN-PROTEIN LIGASE BRE1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8029319|UniProtKB=A0ACM8FZP1 A0ACM8FZP1 LOC8029319 PTHR23252:SF24 INTIMAL THICKNESS RECEPTOR-RELATED TRANSMEMBRANE PROTEIN 145 IXOSC|EnsemblGenome=LOC8030345|UniProtKB=A0ACM8DNC0 A0ACM8DNC0 LOC8030345 PTHR14618:SF0 HOMEODOX-CONTAINING PROTEIN 1 HMBOX1 HOMEOBOX-CONTAINING PROTEIN 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC115311416|UniProtKB=A0ACM8DQR6 A0ACM8DQR6 LOC115311416 PTHR10155:SF32 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING 6 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 kinase modulator#PC00140 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>SOCS#P00879;Interferon-gamma signaling pathway#P00035>SOCS#P00956 IXOSC|EnsemblGenome=LOC121046474|UniProtKB=A0ACM8FDY8 A0ACM8FDY8 LOC121047952 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046762|UniProtKB=A0ACM8FES7 A0ACM8FES7 LOC121046762 PTHR11315:SF0 PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE FOLATE GAMMA-GLUTAMYL HYDROLASE peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC120836367|UniProtKB=A0ACM8EEH9 A0ACM8EEH9 LOC120836367 PTHR46599:SF9 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED 4-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121833864|UniProtKB=A0ACM8FM41 A0ACM8FM41 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836830|UniProtKB=A0ACM8G0X2 A0ACM8G0X2 LOC121836830 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115309676|UniProtKB=A0ACM8DNW2 A0ACM8DNW2 LOC115309676 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115324083|UniProtKB=A0ACM8E3L6 A0ACM8E3L6 LOC115324083 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8040359|UniProtKB=A0ACM8DSR9 A0ACM8DSR9 Ack PTHR24418:SF384 TYROSINE-PROTEIN KINASE ACTIVATED CDC42 KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 IXOSC|EnsemblGenome=LOC115328802|UniProtKB=A0ACM8FT76 A0ACM8FT76 LOC115328802 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120851114|UniProtKB=A0ACM8FB52 A0ACM8FB52 LOC120851114 PTHR45749:SF35 ZINC FINGER MYM-TYPE PROTEIN 1 AC-LIKE TRANSPOSASE-RELATED IXOSC|EnsemblGenome=LOC8043140|UniProtKB=A0ACM8F1U7 A0ACM8F1U7 LOC8043140 PTHR23351:SF24 FOS TRANSCRIPTION FACTOR-RELATED ACTIVATING TRANSCRIPTION FACTOR 3-RELATED basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC8040554|UniProtKB=A0ACM8F3W0 A0ACM8F3W0 LOC8040554 PTHR10663:SF376 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;ruffle#GO:0001726;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC120839511|UniProtKB=A0ACM8ELW0 A0ACM8ELW0 LOC120839511 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8028253|UniProtKB=A0ACM8DJN2 A0ACM8DJN2 JMJD7 PTHR12461:SF99 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND (3S)-LYSYL HYDROXYLASE JMJD7 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8038041|UniProtKB=A0ACM8EIL5 A0ACM8EIL5 LOC8038041 PTHR22780:SF13 ADAPTIN, ALPHA/GAMMA/EPSILON AP-4 COMPLEX SUBUNIT EPSILON-1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8052607|UniProtKB=A0ACM8EXF7 A0ACM8EXF7 PTHR11063:SF28 GLUTAMATE SEMIALDEHYDE DEHYDROGENASE DELTA-1-PYRROLINE-5-CARBOXYLATE SYNTHASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8038204|UniProtKB=A0ACM8FKD2 A0ACM8FKD2 LOC8038204 PTHR23151:SF94 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227 transferase#PC00220;acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC8029795|UniProtKB=A0ACM8G929 A0ACM8G929 LOC8029795 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120849770|UniProtKB=A0ACM8F7C8 A0ACM8F7C8 LOC120849770 PTHR13071:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22 SMALL RIBOSOMAL SUBUNIT PROTEIN MS22 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8053929|UniProtKB=A0ACM8EYX9 A0ACM8EYX9 IleRS-m PTHR42765:SF3 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC120843963|UniProtKB=A0ACM8EX26 A0ACM8EX26 LOC120843963 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115316780|UniProtKB=A0ACM8F658 A0ACM8F658 LOC115316780 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8037359|UniProtKB=A0ACM8FC44 A0ACM8FC44 LOC8037359 PTHR12155:SF49 SCHLAFEN SCHLAFEN ALBA-2 DOMAIN-CONTAINING PROTEIN endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC8037560|UniProtKB=A0ACM8DK47 A0ACM8DK47 LOC8037560 PTHR23407:SF1 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ligase#PC00142 IXOSC|EnsemblGenome=LOC121832858|UniProtKB=A0ACM8FKN4 A0ACM8FKN4 LOC121832858 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 IXOSC|EnsemblGenome=LOC8034392|UniProtKB=A0ACM8E176 A0ACM8E176 Unr PTHR12913:SF1 UNR PROTEIN N-RAS UPSTREAM GENE PROTEIN COLD SHOCK DOMAIN-CONTAINING PROTEIN E1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517 negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;regulation of biosynthetic process#GO:0009889;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC121047215|UniProtKB=A0ACM8FFS7 A0ACM8FFS7 LOC121047215 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850746|UniProtKB=A0ACM8FAT3 A0ACM8FAT3 LOC120850746 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8029018|UniProtKB=A0ACM8E0H7 A0ACM8E0H7 LOC8029018 PTHR13743:SF86 BEIGE/BEACH-RELATED LYSOSOMAL-TRAFFICKING REGULATOR lysosome organization#GO:0007040;cellular process#GO:0009987;lytic vacuole organization#GO:0080171;organelle organization#GO:0006996;cellular component organization#GO:0016043;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840 lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115310671|UniProtKB=A0ACM8DQ86 A0ACM8DQ86 LOC115310671 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850534|UniProtKB=A0ACM8FB19 A0ACM8FB19 LOC120850534 PTHR45823:SF1 T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN SAP DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037058|UniProtKB=A0ACM8DQV9 A0ACM8DQV9 HPS4 PTHR14407:SF11 HERMANSKY-PUDLAK SYNDROME 4 PROTEIN LIGHT-EAR PROTEIN-RELATED HERMANSKY-PUDLAK SYNDROME 4, ISOFORM A GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 localization#GO:0051179;protein targeting#GO:0006605;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8031393|UniProtKB=A0ACM8DN63 A0ACM8DN63 Prosbeta4 PTHR32194:SF16 METALLOPROTEASE TLDD PROTEASOME SUBUNIT BETA cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8035941|UniProtKB=A0ACM8E081 A0ACM8E081 LOC8035941 PTHR11827:SF100 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 9 chloride transmembrane transporter activity#GO:0015108;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8028606|UniProtKB=A0ACM8E7P2 A0ACM8E7P2 PTHR15000:SF1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 ERYTHROID DIFFERENTIATION-RELATED FACTOR 1 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 IXOSC|EnsemblGenome=LOC8042735|UniProtKB=A0ACM8FJP9 A0ACM8FJP9 LOC8042735 PTHR22722:SF17 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR ISOFORM X1 IXOSC|EnsemblGenome=LOC115323217|UniProtKB=A0ACM8F6N0 A0ACM8F6N0 LOC115323217 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8053778|UniProtKB=A0ACM8E6J3 A0ACM8E6J3 LOC8053778 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC115313970|UniProtKB=A0ACM8DT77 A0ACM8DT77 LOC115313970 PTHR11177:SF408 CHITINASE ACIDIC MAMMALIAN CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC120842163|UniProtKB=A0ACM8EUA9 A0ACM8EUA9 LOC120842163 PTHR43435:SF4 RIBULOKINASE FGGY CARBOHYDRATE KINASE DOMAIN-CONTAINING PROTEIN phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate kinase activity#GO:0019200;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137;carbohydrate kinase#PC00065;transferase#PC00220 Ascorbate degradation#P02729>L-xylulose kinase#P02849;Pentose phosphate pathway#P02762>D-Ribulo Kinase#P03077 IXOSC|EnsemblGenome=LOC115324432|UniProtKB=A0ACM8E3X1 A0ACM8E3X1 LOC115324432 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8031737|UniProtKB=A0ACM8E839 A0ACM8E839 LOC8031737 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 IXOSC|EnsemblGenome=LOC120850135|UniProtKB=A0ACM8FA58 A0ACM8FA58 LOC120850135 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120848934|UniProtKB=A0ACM8F7N7 A0ACM8F7N7 LOC120848934 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332448|UniProtKB=A0ACM8EDI1 A0ACM8EDI1 LOC115332448 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036347|UniProtKB=A0ACM8DS88 A0ACM8DS88 Letm1 PTHR14009:SF40 LEUCINE ZIPPER-EF-HAND CONTAINING TRANSMEMBRANE PROTEIN MITOCHONDRIAL PROTON_CALCIUM EXCHANGER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrial calcium ion transmembrane transport#GO:0006851;organelle organization#GO:0006996;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;mitochondrion organization#GO:0007005;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;calcium ion transport#GO:0006816;cellular component organization#GO:0016043;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8028512|UniProtKB=A0ACM8E576 A0ACM8E576 Acf PTHR46510:SF1 BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 1A binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;positive regulation of DNA metabolic process#GO:0051054;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;regulation of DNA replication#GO:0006275;regulation of DNA-templated transcription#GO:0006355;regulation of chromatin organization#GO:1902275;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA replication#GO:0045740;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010 IXOSC|EnsemblGenome=LOC8030220|UniProtKB=A0ACM8FCE5 A0ACM8FCE5 LOC8030220 PTHR10517:SF14 FOLATE RECEPTOR FOLATE RECEPTOR 1-RELATED molecular transducer activity#GO:0060089;cargo receptor activity#GO:0038024;signaling receptor activity#GO:0038023 dicarboxylic acid transport#GO:0006835;vitamin transport#GO:0051180;nitrogen compound transport#GO:0071705;localization#GO:0051179;establishment of localization#GO:0051234;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC115321834|UniProtKB=A0ACM8F970 A0ACM8F970 LOC115321834 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041894|UniProtKB=A0ACM8EU43 A0ACM8EU43 Ent3 PTHR10332:SF93 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;active transmembrane transporter activity#GO:0022804;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleoside transmembrane transporter activity#GO:0005337;nucleobase-containing compound transmembrane transporter activity#GO:0015932 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8027297|UniProtKB=A0ACM8DZB6 A0ACM8DZB6 LOC8027297 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115328400|UniProtKB=A0ACM8F991 A0ACM8F991 LOC115328400 PTHR24185:SF10 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;A2-type glycerophospholipase activity#GO:0004623;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;olefinic compound metabolic process#GO:0120254;fatty acid metabolic process#GO:0006631;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;arachidonate metabolic process#GO:0019369;small molecule metabolic process#GO:0044281;icosanoid metabolic process#GO:0006690 membrane#GO:0016020;cellular anatomical structure#GO:0110165 lipase#PC00143;phospholipase#PC00186;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120841912|UniProtKB=A0ACM8ESQ2 A0ACM8ESQ2 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115323761|UniProtKB=A0ACM8EMG4 A0ACM8EMG4 LOC115323761 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8026440|UniProtKB=A0ACM8DHS2 A0ACM8DHS2 LOC8026440 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115315738|UniProtKB=A0ACM8DVM8 A0ACM8DVM8 LOC115315738 PTHR46165:SF8 SET AND MYND DOMAIN-CONTAINING PROTEIN 4 DOWN AND OUT, ISOFORM A-RELATED enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515;histone deacetylase binding#GO:0042826 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8052904|UniProtKB=A0ACM8EDW2 A0ACM8EDW2 MED27 PTHR13130:SF4 34 KDA TRANSCRIPTIONAL CO-ACTIVATOR-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 27 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC115312011|UniProtKB=A0ACM8FEK7 A0ACM8FEK7 LOC115312011 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8033195|UniProtKB=A0ACM8DWP4 A0ACM8DWP4 LOC8033195 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8023348|UniProtKB=A0ACM8DNF0 A0ACM8DNF0 LOC8023348 PTHR24370:SF10 OPTICIN LEUCINE-RICH REPEAT AND WD REPEAT-CONTAINING PROTEIN 1 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC115323595|UniProtKB=A0ACM8FB57 A0ACM8FB57 LOC115323595 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121047365|UniProtKB=A0ACM8FG71 A0ACM8FG71 LOC121047365 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;chitin metabolic process#GO:0006030 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8038035|UniProtKB=A0ACM8E6B7 A0ACM8E6B7 Rpb8 PTHR10917:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;RNA polymerase III complex#GO:0005666;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 IXOSC|EnsemblGenome=LOC115325393|UniProtKB=A0ACM8E4V0 A0ACM8E4V0 LOC115325393 PTHR39299:SF1 TRANSMEMBRANE PROTEIN DUF7789 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026945|UniProtKB=A0ACM8DIL7 A0ACM8DIL7 LOC8026945 PTHR12905:SF0 METALLOPHOSPHOESTERASE CALCINEURIN-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8024175|UniProtKB=A0ACM8DMU5 A0ACM8DMU5 LOC8024175 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter#PC00227 IXOSC|EnsemblGenome=LOC115318379|UniProtKB=A0ACM8FXP9 A0ACM8FXP9 Tor PTHR11139:SF134 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE MTOR protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of catabolic process#GO:0009894;regulation of macroautophagy#GO:0016241;negative regulation of autophagy#GO:0010507;negative regulation of cellular process#GO:0048523;TOR signaling#GO:0031929;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;negative regulation of macroautophagy#GO:0016242;signal transduction#GO:0007165;cell communication#GO:0007154;TORC1 signaling#GO:0038202;intracellular signal transduction#GO:0035556;negative regulation of catabolic process#GO:0009895;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;TORC2 signaling#GO:0038203;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;TOR complex#GO:0038201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 p53 pathway by glucose deprivation#P04397>mTOR#P04638;PDGF signaling pathway#P00047>mTOR#P01144;Interleukin signaling pathway#P00036>mTOR#P00966;Hypoxia response via HIF activation#P00030>TOR#P00817 IXOSC|EnsemblGenome=LOC8053611|UniProtKB=A0ACM8E1M5 A0ACM8E1M5 LOC8053611 PTHR42737:SF10 GLUTATHIONE REDUCTASE THIOREDOXIN-DISULFIDE REDUCTASE (NADPH) heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;disulfide oxidoreductase activity#GO:0015036;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488 homeostatic process#GO:0042592;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;modified amino acid metabolic process#GO:0006575;cellular response to stress#GO:0033554;glutathione metabolic process#GO:0006749;cellular response to chemical stimulus#GO:0070887;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;response to stress#GO:0006950;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8031980|UniProtKB=A0ACM8DJ18 A0ACM8DJ18 LOC8031980 PTHR47238:SF2 MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE HEMIPTEROUS non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MKK4,7#P00637;EGF receptor signaling pathway#P00018>MKK4,7#P00555 IXOSC|EnsemblGenome=LOC120849444|UniProtKB=A0ACM8F8R1 A0ACM8F8R1 LOC120849444 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026428|UniProtKB=A0ACM8DHS7 A0ACM8DHS7 LOC8026428 PTHR12606:SF141 SENTRIN/SUMO-SPECIFIC PROTEASE GH15225P-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 protease#PC00190 IXOSC|EnsemblGenome=LOC121833126|UniProtKB=A0ACM8F1J0 A0ACM8F1J0 LOC8026026 PTHR24317:SF7 PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115321098|UniProtKB=A0ACM8EHQ3 A0ACM8EHQ3 LOC115321098 PTHR43762:SF8 L-GULONOLACTONE OXIDASE L-GULONOLACTONE OXIDASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;L-ascorbic acid metabolic process#GO:0019852;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283 oxidoreductase#PC00176;oxidase#PC00175;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040076|UniProtKB=A0ACM8DKF6 A0ACM8DKF6 LOC8040076 PTHR24133:SF60 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT AND SOCS BOX-CONTAINING 3 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120837800|UniProtKB=A0ACM8EIA2 A0ACM8EIA2 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC120835942|UniProtKB=A0ACM8DZF9 A0ACM8DZF9 LOC120835942 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC121833444|UniProtKB=A0ACM8FM09 A0ACM8FM09 LOC121833444 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121832865|UniProtKB=A0ACM8FQF8 A0ACM8FQF8 PTHR47501:SF10 TRANSPOSASE-RELATED DUF659 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8023677|UniProtKB=A0ACM8DUI3 A0ACM8DUI3 Rrp47 PTHR15341:SF3 SUN-COR STEROID HORMONE RECEPTOR CO-REPRESSOR NUCLEAR NUCLEIC ACID-BINDING PROTEIN C1D nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC115325713|UniProtKB=A0ACM8EWF0 A0ACM8EWF0 LOC115325713 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120844587|UniProtKB=A0ACM8EZ34 A0ACM8EZ34 LOC120844587 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8039069|UniProtKB=A0ACM8EKY1 A0ACM8EKY1 LOC8039069 PTHR10857:SF106 COPINE NICOTINIC RECEPTOR-ASSOCIATED PROTEIN 1 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 response to metal ion#GO:0010038;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;response to calcium ion#GO:0051592;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC120847052|UniProtKB=A0ACM8F3K9 A0ACM8F3K9 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844535|UniProtKB=A0ACM8EZ03 A0ACM8EZ03 LOC120844535 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8051019|UniProtKB=A0ACM8F8D0 A0ACM8F8D0 LOC8051019 PTHR12992:SF11 NUDIX HYDROLASE MITOCHONDRIAL COENZYME A DIPHOSPHATASE NUDT8 hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 organophosphate catabolic process#GO:0046434;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8037349|UniProtKB=A0ACM8EBR3 A0ACM8EBR3 Osbp PTHR10972:SF205 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN 1 steroid binding#GO:0005496;lipid binding#GO:0008289;sterol binding#GO:0032934;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8027180|UniProtKB=A0ACM8ES66 A0ACM8ES66 LOC8027180 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC binding#GO:0005488;chromatin binding#GO:0003682 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC120841456|UniProtKB=A0ACM8ERR2 A0ACM8ERR2 LOC120841456 PTHR12673:SF241 FACIOGENITAL DYSPLASIA PROTEIN DH DOMAIN-CONTAINING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;filopodium assembly#GO:0046847;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC115330648|UniProtKB=A0ACM8EGA7 A0ACM8EGA7 LOC115330648 PTHR22576:SF41 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE CASPASE 14, APOPTOSIS-RELATED CYSTEINE PEPTIDASE regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066 cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC8051577|UniProtKB=A0ACM8G758 A0ACM8G758 LOC8051577 PTHR21646:SF14 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITINYL HYDROLASE 1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115309328|UniProtKB=A0ACM8EZR4 A0ACM8EZR4 LOC115309328 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;heart development#GO:0007507;cellular process#GO:0009987;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120840612|UniProtKB=A0ACM8EP15 A0ACM8EP15 LOC120840612 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120839232|UniProtKB=A0ACM8ELH6 A0ACM8ELH6 LOC120839232 PTHR11118:SF1 RNA-SPLICING LIGASE RTCB HOMOLOG RNA-SPLICING LIGASE RTCB catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8031771|UniProtKB=A0ACM8F969 A0ACM8F969 LOC8031771 PTHR34179:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115313589|UniProtKB=A0ACM8G7D9 A0ACM8G7D9 LOC115313589 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314234|UniProtKB=A0ACM8DTZ9 A0ACM8DTZ9 LOC115314234 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842039|UniProtKB=A0ACM8ESY4 A0ACM8ESY4 LOC120842039 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043461|UniProtKB=A0ACM8G5W7 A0ACM8G5W7 LOC8043461 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115331717|UniProtKB=A0ACM8ECF7 A0ACM8ECF7 PTHR24116:SF0 KINASE D-INTERACTING SUBSTRATE OF 220 KDA KINASE D-INTERACTING SUBSTRATE OF 220 KDA enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cell surface receptor signaling pathway#GO:0007166;cellular response to growth factor stimulus#GO:0071363;cellular response to nerve growth factor stimulus#GO:1990090;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;synapse#GO:0045202 IXOSC|EnsemblGenome=LOC8025054|UniProtKB=A0ACM8F9N0 A0ACM8F9N0 LOC8025054 PTHR24406:SF43 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED IP01015P zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8050445|UniProtKB=A0ACM8EFB8 A0ACM8EFB8 LOC8050445 PTHR10590:SF24 SODIUM/NUCLEOSIDE COTRANSPORTER CONCENTRATIVE NUCLEOSIDE TRANSPORTER 1-RELATED carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;nucleobase-containing compound transmembrane transporter activity#GO:0015932;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;nucleoside transmembrane transporter activity#GO:0005337;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC115309196|UniProtKB=A0ACM8DNJ2 A0ACM8DNJ2 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115326670|UniProtKB=A0ACM8ENL1 A0ACM8ENL1 LOC115326670 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837017|UniProtKB=A0ACM8G169 A0ACM8G169 LOC121837017 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120841589|UniProtKB=A0ACM8ES03 A0ACM8ES03 LOC120841589 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120841714|UniProtKB=A0ACM8G4N3 A0ACM8G4N3 LOC120841714 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8030746|UniProtKB=A0ACM8ESE1 A0ACM8ESE1 LOC8030746 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319117|UniProtKB=A0ACM8EKS8 A0ACM8EKS8 LOC115319117 PTHR22812:SF112 CHROMOBOX PROTEIN CHROMATOR, ISOFORM A-RELATED binding#GO:0005488;chromatin binding#GO:0003682 cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007 intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8034553|UniProtKB=A0ACM8F688 A0ACM8F688 PTHR44252:SF3 D-ERYTHRULOSE REDUCTASE D-ERYTHRULOSE REDUCTASE-RELATED alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 glucose metabolic process#GO:0006006;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115328610|UniProtKB=A0ACM8E8X7 A0ACM8E8X7 LOC115328610 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8023629|UniProtKB=A0ACM8DMM6 A0ACM8DMM6 LOC8023629 PTHR23110:SF118 BTB DOMAIN TRANSCRIPTION FACTOR PROTEIN TRAMTRACK, ALPHA ISOFORM regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115327814|UniProtKB=A0ACM8FBH6 A0ACM8FBH6 LOC120849851 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120837088|UniProtKB=A0ACM8EGK3 A0ACM8EGK3 LOC120837088 PTHR24072:SF192 RHO FAMILY GTPASE CDC42 HOMOLOG heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924 cell communication#GO:0007154;localization#GO:0051179;supramolecular fiber organization#GO:0097435;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;establishment of cell polarity#GO:0030010;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;transport#GO:0006810;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein#PC00020;small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;Integrin signalling pathway#P00034>Cdc42#P00938;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;Ras Pathway#P04393>Cdc42#P04569;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Huntington disease#P00029>Rac#P00775;Cytoskeletal regulation by Rho GTPase#P00016>Cdc42#P00515;p38 MAPK pathway#P05918>Cdc42#P06041;Axon guidance mediated by netrin#P00009>cdc42#P00364;FGF signaling pathway#P00021>Rac#P00645;Axon guidance mediated by Slit/Robo#P00008>Cdc42#P00349 IXOSC|EnsemblGenome=LOC115319763|UniProtKB=A0ACM8EV72 A0ACM8EV72 LOC115319763 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037272|UniProtKB=A0ACM8EZG2 A0ACM8EZG2 LOC8037272 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC8031762|UniProtKB=A0ACM8FRL0 A0ACM8FRL0 puf PTHR24006:SF827 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 34 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC121835642|UniProtKB=A0ACM8FV95 A0ACM8FV95 LOC121835642 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8023735|UniProtKB=A0ACM8FDE6 A0ACM8FDE6 Ndae1 PTHR11453:SF36 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;transmembrane transport#GO:0055085;localization#GO:0051179;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115316932|UniProtKB=A0ACM8EJQ0 A0ACM8EJQ0 unc-104 PTHR47117:SF14 STAR-RELATED LIPID TRANSFER PROTEIN 9 KINESIN-LIKE PROTEIN UNC-104 IXOSC|EnsemblGenome=LOC120837940|UniProtKB=A0ACM8EIK7 A0ACM8EIK7 LOC120837940 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120839186|UniProtKB=A0ACM8EKY3 A0ACM8EKY3 LOC120839186 PTHR43710:SF2 2-HYDROXYACYL-COA LYASE 2-HYDROXYACYL-COA LYASE 1 binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;heterocyclic compound binding#GO:1901363 monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lyase#PC00144;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8051020|UniProtKB=A0ACM8DLE9 A0ACM8DLE9 LOC8051020 PTHR13793:SF160 PHD FINGER PROTEINS PHD FINGER PROTEIN RHINOCEROS chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC121838402|UniProtKB=A0ACM8G8Z3 A0ACM8G8Z3 LOC121838402 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120846068|UniProtKB=A0ACM8F1F6 A0ACM8F1F6 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837602|UniProtKB=A0ACM8G470 A0ACM8G470 LOC121837602 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC120840846|UniProtKB=A0ACM8ERC6 A0ACM8ERC6 LOC120840846 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8036473|UniProtKB=A0ACM8E0R6 A0ACM8E0R6 Egfr PTHR24416:SF566 TYROSINE-PROTEIN KINASE RECEPTOR EPIDERMAL GROWTH FACTOR RECEPTOR catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 system development#GO:0048731;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of epithelial cell proliferation#GO:0050679;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;epidermal growth factor receptor signaling pathway#GO:0007173;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;positive regulation of signaling#GO:0023056;generation of neurons#GO:0048699;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of cell population proliferation#GO:0008284;regulation of programmed cell death#GO:0043067;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transmembrane signal receptor#PC00197 Cadherin signaling pathway#P00012>EGFR#P00466;EGF receptor signaling pathway#P00018>EGFR#P00542 IXOSC|EnsemblGenome=LOC120838337|UniProtKB=A0ACM8EKJ4 A0ACM8EKJ4 LOC120838337 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120848854|UniProtKB=A0ACM8F6H4 A0ACM8F6H4 LOC120848854 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8053796|UniProtKB=A0ACM8E991 A0ACM8E991 Vps16B PTHR13364:SF6 DEFECTIVE SPERMATOGENESIS PROTEIN 39 SPERMATOGENESIS-DEFECTIVE PROTEIN 39 HOMOLOG establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vacuolar transport#GO:0007034;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121047796|UniProtKB=A0ACM8FR19 A0ACM8FR19 LOC121047796 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC8031463|UniProtKB=A0ACM8DY84 A0ACM8DY84 ND-B14 PTHR12964:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B14 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 6 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115312042|UniProtKB=A0ACM8DRV3 A0ACM8DRV3 LOC115312042 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960 calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC121835240|UniProtKB=A0ACM8FSZ9 A0ACM8FSZ9 LOC121835240 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324651|UniProtKB=A0ACM8F2B3 A0ACM8F2B3 OstDelta PTHR12640:SF0 RIBOPHORIN II DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 2 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8036378|UniProtKB=A0ACM8E1R4 A0ACM8E1R4 LOC8036378 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120837522|UniProtKB=A0ACM8EHQ0 A0ACM8EHQ0 LOC120837522 PTHR22930:SF269 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309385|UniProtKB=A0ACM8EQ40 A0ACM8EQ40 LOC115309385 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332131|UniProtKB=A0ACM8F181 A0ACM8F181 LOC115332131 PTHR11802:SF201 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CTSA-1.1 catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120844707|UniProtKB=A0ACM8EZB6 A0ACM8EZB6 LOC120844707 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8044097|UniProtKB=A0ACM8DL81 A0ACM8DL81 LOC8044097 PTHR22966:SF76 2-AMINOETHANETHIOL DIOXYGENASE 2-AMINOETHANETHIOL DIOXYGENASE dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 response to hypoxia#GO:0001666;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to abiotic stimulus#GO:0009628;cellular response to hypoxia#GO:0071456;response to stress#GO:0006950;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC120842585|UniProtKB=A0ACM8EV82 A0ACM8EV82 LOC120842585 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834745|UniProtKB=A0ACM8FRA6 A0ACM8FRA6 LOC121834745 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120848090|UniProtKB=A0ACM8F4B9 A0ACM8F4B9 LOC120848090 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316785|UniProtKB=A0ACM8DX15 A0ACM8DX15 LOC115316785 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8026823|UniProtKB=A0ACM8F2K1 A0ACM8F2K1 LOC8026823 PTHR13715:SF79 RYANODINE RECEPTOR AND IP3 RECEPTOR RYANODINE RECEPTOR ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;calcium ion transmembrane import into cytosol#GO:0097553;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;calcium ion transmembrane transport#GO:0070588;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;sarcoplasm#GO:0016528;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sarcoplasmic reticulum#GO:0016529;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 ligand-gated ion channel#PC00141;ion channel#PC00133 Metabotropic glutamate receptor group I pathway#P00041>IP3R#P01056;Beta2 adrenergic receptor signaling pathway#P04378>ER-type Ca2+ channel#P04441;Beta1 adrenergic receptor signaling pathway#P04377>ER-type Ca2+ channel#P04434 IXOSC|EnsemblGenome=LOC115311907|UniProtKB=A0ACM8DRD3 A0ACM8DRD3 LOC115311907 PTHR45036:SF1 METHYLTRANSFERASE LIKE 7B THIOL METHYLTRANSFERASE 1A methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8029227|UniProtKB=A0ACM8E6H1 A0ACM8E6H1 SMC1 PTHR18937:SF12 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cell cycle process#GO:0022402;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cohesin complex#GO:0008278;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8033099|UniProtKB=A0ACM8ED31 A0ACM8ED31 LOC8033099 PTHR46309:SF28 PHD FINGER PROTEIN 12 PHD FINGER PROTEIN 12 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120844076|UniProtKB=A0ACM8EXG5 A0ACM8EXG5 LOC120844076 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120838742|UniProtKB=A0ACM8ELF9 A0ACM8ELF9 LOC120838742 PTHR11675:SF119 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 2 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120848655|UniProtKB=A0ACM8F673 A0ACM8F673 LOC120848655 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120836879|UniProtKB=A0ACM8EGY8 A0ACM8EGY8 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115318662|UniProtKB=A0ACM8DYU9 A0ACM8DYU9 LOC115318662 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120835932|UniProtKB=A0ACM8EF25 A0ACM8EF25 Tace PTHR45702:SF6 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER DISINTEGRIN AND METALLOPROTEINASE DOMAIN-CONTAINING PROTEIN 17 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 membrane protein ectodomain proteolysis#GO:0006509;biological regulation#GO:0065007;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;signal transduction#GO:0007165;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;cell communication#GO:0007154;proteolysis#GO:0006508 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-presenilin pathway#P00004>TACE#P00147;Notch signaling pathway#P00045>TACE#P01105;Alzheimer disease-amyloid secretase pathway#P00003>TACE#P00092 IXOSC|EnsemblGenome=LOC115320367|UniProtKB=A0ACM8FTB1 A0ACM8FTB1 Hem PTHR12093:SF12 NCK-ASSOCIATED PROTEIN 1 MEMBRANE-ASSOCIATED PROTEIN HEM actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;system development#GO:0048731;cortical actin cytoskeleton organization#GO:0030866;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;plasma membrane bounded cell projection organization#GO:0120036;cell migration#GO:0016477;multicellular organismal process#GO:0032501;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115310789|UniProtKB=A0ACM8DQ26 A0ACM8DQ26 LOC115310789 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8051078|UniProtKB=A0ACM8DL97 A0ACM8DL97 LOC8051078 PTHR47760:SF1 G-PROTEIN COUPLED RECEPTOR B0563.6-LIKE PROTEIN-RELATED G PROTEIN-COUPLED RECEPTOR B0563.6-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8039676|UniProtKB=A0ACM8DSF5 A0ACM8DSF5 LOC8039676 PTHR24381:SF470 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8052330|UniProtKB=A0ACM8ERN3 A0ACM8ERN3 LOC8052330 PTHR43108:SF6 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER N-SULPHOGLUCOSAMINE SULPHOHYDROLASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein catabolic process#GO:0030163;glycosaminoglycan catabolic process#GO:0006027;aminoglycan metabolic process#GO:0006022;protein metabolic process#GO:0019538;glycosaminoglycan metabolic process#GO:0030203;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8030997|UniProtKB=A0ACM8G5C6 A0ACM8G5C6 LOC8030997 PTHR45620:SF15 PDF RECEPTOR-LIKE PROTEIN-RELATED DIURETIC HORMONE RECEPTOR molecular transducer activity#GO:0060089;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;peptide hormone binding#GO:0017046;hormone binding#GO:0042562 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8036675|UniProtKB=A0ACM8DK09 A0ACM8DK09 LOC8036675 PTHR46600:SF1 THAP DOMAIN-CONTAINING THAP-TYPE DOMAIN-CONTAINING PROTEIN gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8032707|UniProtKB=A0ACM8DSQ9 A0ACM8DSQ9 LOC8032707 PTHR23308:SF36 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 SMAD NUCLEAR-INTERACTING PROTEIN 1 molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 IXOSC|EnsemblGenome=LOC120846954|UniProtKB=A0ACM8F2S8 A0ACM8F2S8 LOC120846954 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849461|UniProtKB=A0ACM8F7W7 A0ACM8F7W7 LOC120849461 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115328059|UniProtKB=A0ACM8EWI1 A0ACM8EWI1 LOC115328059 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC8040861|UniProtKB=A0ACM8FU20 A0ACM8FU20 LOC8040861 PTHR23345:SF15 VITELLOGENIN-RELATED VITELLOGENIN-6 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 storage protein#PC00210 IXOSC|EnsemblGenome=LOC8042253|UniProtKB=A0ACM8DQU9 A0ACM8DQU9 eIF3e PTHR10317:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC8034337|UniProtKB=A0ACM8FLC7 A0ACM8FLC7 bma PTHR12984:SF16 SCY1-RELATED S/T PROTEIN KINASE-LIKE BLACK MATCH, ISOFORM H non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115314977|UniProtKB=A0ACM8DU85 A0ACM8DU85 LOC115314977 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121838100|UniProtKB=A0ACM8G841 A0ACM8G841 LOC121838100 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028645|UniProtKB=A0ACM8DGZ6 A0ACM8DGZ6 LOC8028645 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121836585|UniProtKB=A0ACM8FZA9 A0ACM8FZA9 LOC121836585 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313563|UniProtKB=A0ACM8DTC9 A0ACM8DTC9 LOC115313563 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115309710|UniProtKB=A0ACM8DP48 A0ACM8DP48 LOC115309710 PTHR11453:SF47 ANION EXCHANGE PROTEIN ANION EXCHANGE PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8030566|UniProtKB=A0ACM8DH92 A0ACM8DH92 LOC8030566 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8033507|UniProtKB=A0ACM8ET65 A0ACM8ET65 LOC8033507 PTHR11848:SF262 TGF-BETA FAMILY DAWDLE cytokine activity#GO:0005125;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 IXOSC|EnsemblGenome=LOC115310624|UniProtKB=A0ACM8FDU9 A0ACM8FDU9 LOC115310624 PTHR24409:SF441 ZINC FINGER PROTEIN 142 TRANSCRIPTIONAL REPRESSOR CTCF DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121834676|UniProtKB=A0ACM8FPG5 A0ACM8FPG5 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836357|UniProtKB=A0ACM8EFE8 A0ACM8EFE8 LOC120836357 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8031650|UniProtKB=A0ACM8DVV6 A0ACM8DVV6 LOC8031650 PTHR22975:SF9 UBIQUITIN SPECIFIC PROTEINASE ECHINUS SPLICE FORM 3 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC120847936|UniProtKB=A0ACM8FMP6 A0ACM8FMP6 LOC120847936 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316313|UniProtKB=A0ACM8ER84 A0ACM8ER84 LOC115316313 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115332979|UniProtKB=A0ACM8EDV6 A0ACM8EDV6 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039598|UniProtKB=A0ACM8EB29 A0ACM8EB29 PTHR12268:SF13 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121835034|UniProtKB=A0ACM8FS60 A0ACM8FS60 LOC121835034 PTHR13612:SF0 ENHANCER OF MRNA-DECAPPING PROTEIN 3 ENHANCER OF MRNA-DECAPPING PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;molecular condensate scaffold activity#GO:0140693;RNA binding#GO:0003723 cellular process#GO:0009987;mRNA catabolic process#GO:0006402;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component assembly#GO:0022607;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;P-body assembly#GO:0033962;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;RNA decapping#GO:0110154 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC115316307|UniProtKB=A0ACM8DVW6 A0ACM8DVW6 LOC115316307 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120848884|UniProtKB=A0ACM8F6K7 A0ACM8F6K7 LOC120848884 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120850737|UniProtKB=A0ACM8F9K6 A0ACM8F9K6 LOC120850737 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115325367|UniProtKB=A0ACM8FWI5 A0ACM8FWI5 LOC115325367 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8042748|UniProtKB=A0ACM8EBX0 A0ACM8EBX0 TpnT PTHR11521:SF1 TROPONIN T TROPONIN T, SKELETAL MUSCLE protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;muscle system process#GO:0003012;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;anatomical structure formation involved in morphogenesis#GO:0048646;striated muscle cell differentiation#GO:0051146;cellular anatomical entity morphogenesis#GO:0032989;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;multicellular organismal process#GO:0032501;cellular developmental process#GO:0048869;system process#GO:0003008;muscle contraction#GO:0006936;developmental process#GO:0032502 sarcomere#GO:0030017;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;contractile muscle fiber#GO:0043292;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myofibril#GO:0030016;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 actin binding motor protein#PC00040 IXOSC|EnsemblGenome=LOC8037136|UniProtKB=A0ACM8F6P6 A0ACM8F6P6 LOC8037136 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8050922|UniProtKB=A0ACM8E6M2 A0ACM8E6M2 LOC8050922 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115329619|UniProtKB=A0ACM8EV54 A0ACM8EV54 LOC115329619 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115328908|UniProtKB=A0ACM8E8Q7 A0ACM8E8Q7 LOC115328908 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8038243|UniProtKB=A0ACM8DM96 A0ACM8DM96 betaCOP PTHR10635:SF0 COATOMER SUBUNIT BETA COATOMER SUBUNIT BETA cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;COPI-coated vesicle#GO:0030137;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506 vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC120849943|UniProtKB=A0ACM8F946 A0ACM8F946 LOC120849943 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8040749|UniProtKB=A0ACM8DH27 A0ACM8DH27 LOC8040749 PTHR11010:SF128 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120842845|UniProtKB=A0ACM8EUS1 A0ACM8EUS1 PTHR24317:SF7 PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;diterpenoid metabolic process#GO:0016101 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8023247|UniProtKB=A0ACM8DGL6 A0ACM8DGL6 stas PTHR43220:SF18 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41B autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;organelle assembly#GO:0070925;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115327381|UniProtKB=A0ACM8EML7 A0ACM8EML7 LOC115327381 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036200|UniProtKB=A0ACM8EBG2 A0ACM8EBG2 LOC8036200 PTHR43191:SF2 RRNA METHYLTRANSFERASE 3, RRNA METHYLTRANSFERASE 3, MITOCHONDRIAL RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC115319529|UniProtKB=A0ACM8FJ61 A0ACM8FJ61 LOC115319529 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8031079|UniProtKB=A0ACM8FKS2 A0ACM8FKS2 LOC8031079 PTHR23193:SF23 NUCLEAR PORE COMPLEX PROTEIN NUP NUCLEAR PORE COMPLEX PROTEIN NUP153 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142;structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transporter#PC00227 IXOSC|EnsemblGenome=LOC115314723|UniProtKB=A0ACM8FCY6 A0ACM8FCY6 LOC115314723 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8050388|UniProtKB=A0ACM8DR06 A0ACM8DR06 LOC8050388 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115313313|UniProtKB=A0ACM8FP61 A0ACM8FP61 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8029981|UniProtKB=A0ACM8EB83 A0ACM8EB83 Deaf1 PTHR10237:SF15 DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG SUPPRESSIN DEFORMED EPIDERMAL AUTOREGULATORY FACTOR 1 HOMOLOG transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115315754|UniProtKB=A0ACM8EGC7 A0ACM8EGC7 LOC115315754 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120840109|UniProtKB=A0ACM8EN85 A0ACM8EN85 LOC120840109 PTHR33361:SF2 GLR0591 PROTEIN DUF885 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849269|UniProtKB=A0ACM8F7T1 A0ACM8F7T1 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115330062|UniProtKB=A0ACM8EAA3 A0ACM8EAA3 LOC115330062 PTHR48575:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850189|UniProtKB=A0ACM8G0J4 A0ACM8G0J4 LOC120850189 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC120838243|UniProtKB=A0ACM8FDL4 A0ACM8FDL4 LOC120838243 PTHR22014:SF2 RNA-BINDING PROTEIN 33 RNA-BINDING PROTEIN 33 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 IXOSC|EnsemblGenome=LOC8028671|UniProtKB=A0ACM8E9I8 A0ACM8E9I8 LOC8028671 PTHR10985:SF141 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED TRANSCRIPTION FACTOR CWO sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;regulation of circadian rhythm#GO:0042752;negative regulation of macromolecule metabolic process#GO:0010605;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;Notch signaling pathway#GO:0007219;regulation of gene expression#GO:0010468;regulation of neurogenesis#GO:0050767;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of multicellular organismal process#GO:0051239;anterior/posterior pattern specification#GO:0009952;cell surface receptor signaling pathway#GO:0007166;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8029881|UniProtKB=A0ACM8FW65 A0ACM8FW65 LOC8029881 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC115309940|UniProtKB=A0ACM8EQ14 A0ACM8EQ14 LOC115309940 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120847699|UniProtKB=A0ACM8F5H0 A0ACM8F5H0 LOC120847699 PTHR11475:SF147 OXIDASE/PEROXIDASE PEROXIDASIN oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC8038339|UniProtKB=A0ACM8DK33 A0ACM8DK33 LOC8038339 PTHR45624:SF61 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER basic amino acid transmembrane transporter activity#GO:0015174;L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;cellular localization#GO:0051641;mitochondrial transmembrane transport#GO:1990542;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;L-alpha-amino acid transmembrane transport#GO:1902475 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 IXOSC|EnsemblGenome=LOC8026099|UniProtKB=A0ACM8E352 A0ACM8E352 LOC8026099 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8035274|UniProtKB=A0ACM8EPG4 A0ACM8EPG4 LOC8035274 PTHR10288:SF356 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120841061|UniProtKB=A0ACM8EQF9 A0ACM8EQF9 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121838121|UniProtKB=A0ACM8G7V7 A0ACM8G7V7 LOC121838121 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8028287|UniProtKB=A0ACM8E506 A0ACM8E506 Mccc1 PTHR18866:SF33 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE METHYLCROTONOYL-COA CARBOXYLASE SUBUNIT ALPHA, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC115319666|UniProtKB=A0ACM8EFZ6 A0ACM8EFZ6 LOC115319666 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8034085|UniProtKB=A0ACM8DIW2 A0ACM8DIW2 LOC8034085 PTHR20903:SF0 PREFOLDIN SUBUNIT 1-RELATED PREFOLDIN SUBUNIT 1 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121837031|UniProtKB=A0ACM8G115 A0ACM8G115 LOC121837031 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115313182|UniProtKB=A0ACM8DSI8 A0ACM8DSI8 LOC115313182 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8041560|UniProtKB=A0ACM8F5J9 A0ACM8F5J9 LOC8041560 PTHR45873:SF1 DNA POLYMERASE ETA DNA POLYMERASE ETA DNA-directed DNA polymerase activity#GO:0003887;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;response to radiation#GO:0009314;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;replication fork#GO:0005657;site of double-strand break#GO:0035861;chromosome#GO:0005694;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121834770|UniProtKB=A0ACM8FR05 A0ACM8FR05 LOC121834770 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115308336|UniProtKB=A0ACM8DMA8 A0ACM8DMA8 LOC115308336 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8050411|UniProtKB=A0ACM8EE91 A0ACM8EE91 PTHR46661:SF4 E3 UBIQUITIN-PROTEIN LIGASE ZNRF1-LIKE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE ZNRF1 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115325154|UniProtKB=A0ACM8FN69 A0ACM8FN69 PTHR23098:SF16 AGAP001331-PA-RELATED GT1 DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121835125|UniProtKB=A0ACM8FT26 A0ACM8FT26 LOC121835125 PTHR23235:SF196 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121833888|UniProtKB=A0ACM8FM56 A0ACM8FM56 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;response to stimulus#GO:0050896;cell cycle process#GO:0022402;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;homologous recombination#GO:0035825;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC115326938|UniProtKB=A0ACM8E7X8 A0ACM8E7X8 LOC115326938 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115311330|UniProtKB=A0ACM8F037 A0ACM8F037 LOC115311330 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120849200|UniProtKB=A0ACM8F7C5 A0ACM8F7C5 LOC120849200 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8032295|UniProtKB=A0ACM8F099 A0ACM8F099 LOC8032295 PTHR24126:SF14 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANK_REP_REGION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835427|UniProtKB=A0ACM8FT66 A0ACM8FT66 LOC121835427 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120850869|UniProtKB=A0ACM8F9W5 A0ACM8F9W5 LOC120850869 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115324321|UniProtKB=A0ACM8E4I8 A0ACM8E4I8 LOC115324321 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121836547|UniProtKB=A0ACM8G016 A0ACM8G016 LOC121836547 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033159|UniProtKB=A0ACM8E205 A0ACM8E205 LOC8033159 PTHR10151:SF131 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE CHOLINEPHOSPHODIESTERASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120847077|UniProtKB=A0ACM8FPP4 A0ACM8FPP4 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319651|UniProtKB=A0ACM8ESX6 A0ACM8ESX6 LOC115319651 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8030222|UniProtKB=A0ACM8EGJ3 A0ACM8EGJ3 LOC8030222 PTHR24373:SF406 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TARTAN, ISOFORM B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8051916|UniProtKB=A0ACM8F209 A0ACM8F209 LOC8051916 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120836637|UniProtKB=A0ACM8EF50 A0ACM8EF50 LOC120836637 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837978|UniProtKB=A0ACM8G624 A0ACM8G624 LOC121837978 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8026220|UniProtKB=A0ACM8EDW0 A0ACM8EDW0 tsu PTHR45894:SF1 RNA-BINDING PROTEIN 8A RNA-BINDING PROTEIN 8A nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8028434|UniProtKB=A0ACM8DGF1 A0ACM8DGF1 LOC8028434 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120839540|UniProtKB=A0ACM8ELF8 A0ACM8ELF8 LOC120839540 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328423|UniProtKB=A0ACM8E8N3 A0ACM8E8N3 LOC115328423 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031107|UniProtKB=A0ACM8DHY9 A0ACM8DHY9 Stoml2 PTHR43327:SF10 STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL STOMATIN-LIKE PROTEIN 2, MITOCHONDRIAL transporter#PC00227 IXOSC|EnsemblGenome=LOC120846865|UniProtKB=A0ACM8F3G8 A0ACM8F3G8 msn PTHR47096:SF1 MISSHAPEN LIKE KINASE 1 NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE IXOSC|EnsemblGenome=LOC115329651|UniProtKB=A0ACM8EAE8 A0ACM8EAE8 LOC115329651 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8039796|UniProtKB=A0ACM8DVT8 A0ACM8DVT8 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic ion homeostasis#GO:0050801 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8029641|UniProtKB=A0ACM8EBW5 A0ACM8EBW5 LOC8029641 PTHR11616:SF333 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;amino acid transmembrane transporter activity#GO:0015171;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8023138|UniProtKB=A0ACM8E856 A0ACM8E856 LOC8023138 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850042|UniProtKB=A0ACM8F7W9 A0ACM8F7W9 LOC120850042 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115330506|UniProtKB=A0ACM8EVP8 A0ACM8EVP8 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8051595|UniProtKB=A0ACM8DLX7 A0ACM8DLX7 LOC8051595 PTHR12149:SF8 FRUCTOSAMINE 3 KINASE-RELATED PROTEIN PROTEIN-RIBULOSAMINE 3-KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein repair#GO:0030091;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 IXOSC|EnsemblGenome=LOC8033721|UniProtKB=A0ACM8EPG3 A0ACM8EPG3 LOC8033721 PTHR14402:SF10 RECEPTOR TRANSPORTING PROTEIN RECEPTOR-TRANSPORTING PROTEIN 3 G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular localization#GO:0051641;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;intracellular protein localization#GO:0008104;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;protein targeting#GO:0006605;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;cellular component organization#GO:0016043;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8042940|UniProtKB=A0ACM8DL09 A0ACM8DL09 LOC8042940 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8023516|UniProtKB=A0ACM8ELA8 A0ACM8ELA8 PTHR13083:SF3 WD REPEAT-CONTAINING PROTEIN 91 WD REPEAT-CONTAINING PROTEIN 91 kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;early endosome membrane#GO:0031901;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC8042610|UniProtKB=A0ACM8FL26 A0ACM8FL26 LOC8042610 PTHR11214:SF411 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8030663|UniProtKB=A0ACM8DMT3 A0ACM8DMT3 Hat1 PTHR12046:SF0 HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT HISTONE ACETYLTRANSFERASE TYPE B CATALYTIC SUBUNIT histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115311112|UniProtKB=A0ACM8DQH8 A0ACM8DQH8 LOC115311112 PTHR31606:SF1 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN BINDING PROTEIN 2, ISOFORM E chromatin DNA binding#GO:0031490;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120840462|UniProtKB=A0ACM8EPB5 A0ACM8EPB5 LOC120840462 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8037669|UniProtKB=A0ACM8DI72 A0ACM8DI72 Dhdds PTHR10291:SF51 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;isoprenoid metabolic process#GO:0006720;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;small molecule biosynthetic process#GO:0044283 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8050786|UniProtKB=A0ACM8DLW3 A0ACM8DLW3 LOC8050786 PTHR11835:SF60 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;alcohol metabolic process#GO:0006066;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;tricarboxylic acid cycle#GO:0006099;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120846422|UniProtKB=A0ACM8F1J9 A0ACM8F1J9 LOC120846422 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120850564|UniProtKB=A0ACM8FAG5 A0ACM8FAG5 LOC120850564 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8038189|UniProtKB=A0ACM8FGI7 A0ACM8FGI7 LOC8038189 PTHR15052:SF2 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR COMPLEX SUBUNIT GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;rDNA binding#GO:0000182;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 rRNA transcription#GO:0009303;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription factor TFIIIC complex#GO:0000127;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121046978|UniProtKB=A0ACM8FDZ8 A0ACM8FDZ8 LOC121046978 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC121837214|UniProtKB=A0ACM8G2E8 A0ACM8G2E8 LOC121837214 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8044022|UniProtKB=A0ACM8EL17 A0ACM8EL17 LOC8044022 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051547|UniProtKB=A0ACM8DLX3 A0ACM8DLX3 LOC8051547 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;glutathione transferase activity#GO:0004364;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;antioxidant activity#GO:0016209;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121835452|UniProtKB=A0ACM8FUS3 A0ACM8FUS3 LOC121835452 PTHR47333:SF9 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 1 ISOFORM X1 IXOSC|EnsemblGenome=LOC8036095|UniProtKB=A0ACM8DJX0 A0ACM8DJX0 LOC8036095 PTHR46949:SF1 LEUCINE REPEAT ADAPTER PROTEIN 25 AT07979P2 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120846647|UniProtKB=A0ACM8F2X0 A0ACM8F2X0 LOC120846647 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8050699|UniProtKB=A0ACM8DLR5 A0ACM8DLR5 LOC8050699 PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121833133|UniProtKB=A0ACM8FKJ0 A0ACM8FKJ0 LOC121833133 PTHR31912:SF38 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840620|UniProtKB=A0ACM8EP27 A0ACM8EP27 LOC120840620 PTHR37162:SF11 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028359|UniProtKB=A0ACM8FEE0 A0ACM8FEE0 LOC8028359 PTHR14978:SF0 BETA-CATENIN-LIKE PROTEIN 1 NUCLEAR ASSOCIATED PROTEIN BETA-CATENIN-LIKE PROTEIN 1 mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 IXOSC|EnsemblGenome=LOC115310140|UniProtKB=A0ACM8EGJ0 A0ACM8EGJ0 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120844818|UniProtKB=A0ACM8EZM1 A0ACM8EZM1 LOC120844818 PTHR23080:SF63 THAP DOMAIN PROTEIN DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313145|UniProtKB=A0ACM8DSG5 A0ACM8DSG5 LOC115313145 PTHR15154:SF2 HAMARTIN HAMARTIN negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cell population proliferation#GO:0008285;regulation of TOR signaling#GO:0032006;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cell population proliferation#GO:0042127;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC1#P04495;p53 pathway by glucose deprivation#P04397>TSC1#P04645 IXOSC|EnsemblGenome=LOC8052907|UniProtKB=A0ACM8FIL5 A0ACM8FIL5 LOC8052907 PTHR13707:SF23 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120846074|UniProtKB=A0ACM8F187 A0ACM8F187 LOC120846074 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121836069|UniProtKB=A0ACM8FX35 A0ACM8FX35 LOC121836069 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034901|UniProtKB=A0ACM8E4J0 A0ACM8E4J0 LOC8034901 PTHR10791:SF112 RAG1-ACTIVATING PROTEIN 1 SUGAR TRANSPORTER SWEET1 carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8029812|UniProtKB=A0ACM8ECE5 A0ACM8ECE5 LOC8029812 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121835606|UniProtKB=A0ACM8FV28 A0ACM8FV28 LOC121835606 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115321224|UniProtKB=A0ACM8EL10 A0ACM8EL10 LOC115321224 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043785|UniProtKB=A0ACM8DQ99 A0ACM8DQ99 LOC8043785 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120838833|UniProtKB=A0ACM8EKK3 A0ACM8EKK3 LOC120838833 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleotide catabolic process#GO:0009166 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC120836997|UniProtKB=A0ACM8EGA8 A0ACM8EGA8 LOC120836997 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115311043|UniProtKB=A0ACM8F8P5 A0ACM8F8P5 LOC115311043 PTHR24390:SF79 ZINC FINGER PROTEIN LD33778P transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120847042|UniProtKB=A0ACM8F2Y8 A0ACM8F2Y8 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025830|UniProtKB=A0ACM8FLI7 A0ACM8FLI7 LOC8025830 PTHR43684:SF18 FAMILY NOT NAMED DODECENOYL-COA DELTA-ISOMERASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity#GO:0003824 monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8032946|UniProtKB=A0ACM8DH91 A0ACM8DH91 LOC8032946 PTHR11954:SF22 D-DOPACHROME DECARBOXYLASE D-DOPACHROME DECARBOXYLASE catalytic activity#GO:0003824;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 decarboxylase#PC00089;lyase#PC00144;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115320229|UniProtKB=A0ACM8F8P7 A0ACM8F8P7 LOC115320229 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8028205|UniProtKB=A0ACM8DRI3 A0ACM8DRI3 LOC8028205 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8036938|UniProtKB=A0ACM8E3G0 A0ACM8E3G0 LOC8036938 PTHR14058:SF8 AMYLOID BETA A4 PRECURSOR PROTEIN-BINDING FAMILY B PROTEIN FE65 HOMOLOG peptide binding#GO:0042277;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8039334|UniProtKB=A0ACM8G0X8 A0ACM8G0X8 LOC8039334 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8024144|UniProtKB=A0ACM8DV63 A0ACM8DV63 LOC8024144 PTHR33236:SF13 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038121|UniProtKB=A0ACM8DQ68 A0ACM8DQ68 LOC8038121 PTHR11214:SF411 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120842795|UniProtKB=A0ACM8EUN1 A0ACM8EUN1 LOC120842795 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;binding#GO:0005488;steroid hydroxylase activity#GO:0008395;tetrapyrrole binding#GO:0046906 response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;steroid metabolic process#GO:0008202 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8041062|UniProtKB=A0ACM8G3D4 A0ACM8G3D4 LOC8041062 PTHR10264:SF127 BAND 7 PROTEIN-RELATED BAND 7 PROTEIN CG42540 ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8028864|UniProtKB=A0ACM8DNA9 A0ACM8DNA9 nmo PTHR24055:SF391 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MAPK#P00835;Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Parkinson disease#P00049>ERK#P01211;Wnt signaling pathway#P00057>Nemo-like Kinase#P01449;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;TGF-beta signaling pathway#P00052>p42/p44MAPKs#P01293;Apoptosis signaling pathway#P00006>MAPK#P00269;FGF signaling pathway#P00021>ERK1-2#P00627;Endothelin signaling pathway#P00019>ERK#P00566;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ERK#P00889;EGF receptor signaling pathway#P00018>ERK1-2#P00543 IXOSC|EnsemblGenome=LOC121838095|UniProtKB=A0ACM8G6Q9 A0ACM8G6Q9 LOC121838095 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838422|UniProtKB=A0ACM8EJ83 A0ACM8EJ83 LOC120838422 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053283|UniProtKB=A0ACM8DL83 A0ACM8DL83 LOC8053283 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115322536|UniProtKB=A0ACM8E269 A0ACM8E269 LOC115322536 PTHR12203:SF122 KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED GLYCOSYL TRANSFERASE CAP10 DOMAIN-CONTAINING PROTEIN hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC115330126|UniProtKB=A0ACM8F8X0 A0ACM8F8X0 LOC115330126 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115329307|UniProtKB=A0ACM8E9E6 A0ACM8E9E6 LOC115329307 PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on RNA#GO:0140098 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8053274|UniProtKB=A0ACM8ECF4 A0ACM8ECF4 PTHR12428:SF66 OXA1 MITOCHONDRIAL INNER MEMBRANE PROTEIN OXA1L protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;membrane organization#GO:0061024 organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transporter#PC00227 IXOSC|EnsemblGenome=LOC120843091|UniProtKB=A0ACM8EWD2 A0ACM8EWD2 LOC120843091 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840654|UniProtKB=A0ACM8EPQ7 A0ACM8EPQ7 LOC120840654 PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137 IXOSC|EnsemblGenome=LOC8031792|UniProtKB=A0ACM8F3I1 A0ACM8F3I1 LOC8031792 PTHR24241:SF190 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CARDIOACCELERATORY PEPTIDE RECEPTOR-LIKE PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120837129|UniProtKB=A0ACM8EGL0 A0ACM8EGL0 LOC120837129 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035218|UniProtKB=A0ACM8EGR1 A0ACM8EGR1 LOC8035218 PTHR23345:SF38 VITELLOGENIN-RELATED APOLIPOPROTEIN LIPID TRANSFER PARTICLE molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 storage protein#PC00210 IXOSC|EnsemblGenome=LOC8040188|UniProtKB=A0ACM8FIY9 A0ACM8FIY9 LOC8040188 PTHR13817:SF175 TITIN NEUROGLIAN structural protein#PC00211 IXOSC|EnsemblGenome=LOC120846941|UniProtKB=A0ACM8F2R6 A0ACM8F2R6 LOC120846941 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837849|UniProtKB=A0ACM8G5E2 A0ACM8G5E2 LOC121837849 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318213|UniProtKB=A0ACM8DYJ2 A0ACM8DYJ2 LOC115318213 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120846795|UniProtKB=A0ACM8F309 A0ACM8F309 LOC120846795 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC8027361|UniProtKB=A0ACM8FLA7 A0ACM8FLA7 LOC8027361 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8036612|UniProtKB=A0ACM8DTZ5 A0ACM8DTZ5 LOC8036612 PTHR21564:SF5 BRAKELESS PROTEIN SCRIBBLER, ISOFORM J regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121836437|UniProtKB=A0ACM8FYP4 A0ACM8FYP4 LOC121836437 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC115308193|UniProtKB=A0ACM8DUM3 A0ACM8DUM3 LOC115308193 PTHR47958:SF104 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE WM6 catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions#GO:0000375;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8037543|UniProtKB=A0ACM8EY58 A0ACM8EY58 LOC8037543 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;catalytic activity#GO:0003824 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC120846986|UniProtKB=A0ACM8FTJ2 A0ACM8FTJ2 LOC120846986 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC121832898|UniProtKB=A0ACM8G760 A0ACM8G760 LOC121832898 PTHR21494:SF3 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 IXOSC|EnsemblGenome=LOC121834305|UniProtKB=A0ACM8FX97 A0ACM8FX97 LOC121838038 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8036317|UniProtKB=A0ACM8F6V0 A0ACM8F6V0 LOC8036317 PTHR24373:SF406 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TARTAN, ISOFORM B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8031644|UniProtKB=A0ACM8DXX7 A0ACM8DXX7 Prosbeta3 PTHR32194:SF10 METALLOPROTEASE TLDD PROTEASOME SUBUNIT BETA TYPE-3 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8036604|UniProtKB=A0ACM8ED52 A0ACM8ED52 LOC8036604 PTHR24027:SF447 CADHERIN-23 CADHERIN-89D-RELATED beta-catenin binding#GO:0008013;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;cell motility#GO:0048870;cell migration#GO:0016477 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 cadherin#PC00057;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115324653|UniProtKB=A0ACM8E4V3 A0ACM8E4V3 LOC115324653 PTHR11414:SF21 CYSTATIN FAMILY MEMBER CYSTATIN 14B, TANDEM DUPLICATE 2-RELATED cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8023137|UniProtKB=A0ACM8FJC8 A0ACM8FJC8 nuf PTHR15726:SF7 RAB11-FAMILY INTERACTING PROTEIN NUCLEAR FALLOUT, ISOFORM J biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;regulation of cell cycle#GO:0051726;endocytic recycling#GO:0032456;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302 cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cell division site#GO:0032153;plasma membrane#GO:0005886;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;recycling endosome#GO:0055037;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;cleavage furrow#GO:0032154;vesicle#GO:0031982;midbody#GO:0030496;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139 IXOSC|EnsemblGenome=LOC8054051|UniProtKB=A0ACM8G3T1 A0ACM8G3T1 LOC8054051 PTHR16213:SF79 SELENOPROTEIN N EF-HAND DOMAIN-CONTAINING PROTEIN inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;monoatomic ion homeostasis#GO:0050801;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8027741|UniProtKB=A0ACM8G345 A0ACM8G345 LOC8027741 PTHR45080:SF47 CONTACTIN 5 IG-LIKE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;cell junction organization#GO:0034330 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005;axon#GO:0030424 IXOSC|EnsemblGenome=LOC8040537|UniProtKB=A0ACM8ECY5 A0ACM8ECY5 uif PTHR45836:SF23 SLIT HOMOLOG NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;axonogenesis#GO:0007409;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;axon guidance#GO:0007411;axon development#GO:0061564;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cellular developmental process#GO:0048869;Notch signaling pathway#GO:0007219;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 IXOSC|EnsemblGenome=LOC115328173|UniProtKB=A0ACM8E8G1 A0ACM8E8G1 LOC115328173 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8028622|UniProtKB=A0ACM8DGW5 A0ACM8DGW5 LOC8028622 PTHR14920:SF0 OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN WD REPEAT DOMAIN 19 cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;cell projection organization#GO:0030030;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;cilium#GO:0005929 IXOSC|EnsemblGenome=LOC115322169|UniProtKB=A0ACM8FBC1 A0ACM8FBC1 LOC115322169 PTHR10543:SF152 BETA-CAROTENE DIOXYGENASE CAROTENOID ISOMEROOXYGENASE catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 diterpenoid metabolic process#GO:0016101;retinoid metabolic process#GO:0001523;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;olefinic compound metabolic process#GO:0120254;catabolic process#GO:0009056;lipid catabolic process#GO:0016042;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;primary metabolic process#GO:0044238 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8039801|UniProtKB=A0ACM8FM08 A0ACM8FM08 VGAT PTHR22950:SF689 AMINO ACID TRANSPORTER VESICULAR INHIBITORY AMINO ACID TRANSPORTER ISOFORM X1 amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333 vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8041079|UniProtKB=A0ACM8F1R4 A0ACM8F1R4 LOC8041079 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115311868|UniProtKB=A0ACM8ESR6 A0ACM8ESR6 LOC115311868 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC121832895|UniProtKB=A0ACM8FWW5 A0ACM8FWW5 LOC121832895 PTHR12606:SF141 SENTRIN/SUMO-SPECIFIC PROTEASE GH15225P-RELATED catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190 IXOSC|EnsemblGenome=LOC120844704|UniProtKB=A0ACM8G6X3 A0ACM8G6X3 LOC120844704 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8041254|UniProtKB=A0ACM8FG11 A0ACM8FG11 LOC8041254 PTHR24028:SF146 CADHERIN-87A CADHERIN-87A cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Wnt signaling pathway#P00057>Cadherin#P01440;Cadherin signaling pathway#P00012>Cadherin#P00471 IXOSC|EnsemblGenome=LOC121833110|UniProtKB=A0ACM8FIA0 A0ACM8FIA0 LOC121833110 PTHR13707:SF23 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120849108|UniProtKB=A0ACM8F747 A0ACM8F747 LOC120849108 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC115313731|UniProtKB=A0ACM8F4Z6 A0ACM8F4Z6 LOC115313731 PTHR12855:SF10 DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219 H4 histone acetyltransferase complex#GO:1902562;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233;acetyltransferase complex#GO:1902493;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8052944|UniProtKB=A0ACM8E127 A0ACM8E127 LOC8052944 PTHR24252:SF48 ACROSIN-RELATED CHYMOTRYPSIN ELASTASE FAMILY MEMBER 2A-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8042521|UniProtKB=A0ACM8E4D9 A0ACM8E4D9 LOC8042521 PTHR15832:SF2 SHC (SRC HOMOLOGY DOMAIN C-TERMINAL) ADAPTOR HOMOLOG SH2 DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121046977|UniProtKB=A0ACM8FSQ9 A0ACM8FSQ9 LOC121046977 PTHR14421:SF3 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 SPERMATOGENESIS-ASSOCIATED PROTEIN 1 IXOSC|EnsemblGenome=LOC121837049|UniProtKB=A0ACM8G1A2 A0ACM8G1A2 LOC121837049 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120848424|UniProtKB=A0ACM8F4V6 A0ACM8F4V6 LOC120848424 PTHR33977:SF1 ZINC ION BINDING PROTEIN ZINC ION BINDING PROTEIN IXOSC|EnsemblGenome=LOC8044002|UniProtKB=A0ACM8E5M6 A0ACM8E5M6 LOC8044002 PTHR30543:SF21 CHROMATE REDUCTASE NAD(P)H-DEPENDENT FMN REDUCTASE LOT6 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H#GO:0016651;catalytic activity#GO:0003824 cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836093|UniProtKB=A0ACM8FYH4 A0ACM8FYH4 LOC121836093 PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;histone modifying activity#GO:0140993;protein serine/threonine kinase activity#GO:0004674;histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8025085|UniProtKB=A0ACM8E868 A0ACM8E868 LOC8025085 PTHR23042:SF99 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS PROTEIN CYCLE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 Circadian clock system#P00015>BMAL1#P00506;Circadian clock system#P00015>bmal1#G01500;Circadian clock system#P00015>bmal1#G01504 IXOSC|EnsemblGenome=LOC8040319|UniProtKB=A0ACM8E8V6 A0ACM8E8V6 LOC8040319 PTHR21243:SF21 PROTEIN SCAI PROTEIN SCAI transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115310797|UniProtKB=A0ACM8FLK9 A0ACM8FLK9 LOC115310797 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121048038|UniProtKB=A0ACM8FHG9 A0ACM8FHG9 LOC121048038 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330107|UniProtKB=A0ACM8EJZ2 A0ACM8EJZ2 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030468|UniProtKB=A0ACM8E7R6 A0ACM8E7R6 KLHL18 PTHR24412:SF497 KELCH PROTEIN KELCH-LIKE PROTEIN 18 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121047397|UniProtKB=A0ACM8G3C0 A0ACM8G3C0 LOC121047397 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120847790|UniProtKB=A0ACM8F4M9 A0ACM8F4M9 LOC120847790 PTHR10751:SF144 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 heterotrimeric G-protein#PC00117;G-protein#PC00020 IXOSC|EnsemblGenome=LOC120850576|UniProtKB=A0ACM8F933 A0ACM8F933 LOC120850576 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120845934|UniProtKB=A0ACM8F1Z1 A0ACM8F1Z1 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC8033910|UniProtKB=A0ACM8EF12 A0ACM8EF12 LOC8033910 PTHR10060:SF15 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8043723|UniProtKB=A0ACM8G0Y7 A0ACM8G0Y7 LOC8043723 PTHR11920:SF512 GUANYLYL CYCLASE RECEPTOR-TYPE GUANYLATE CYCLASE GCY-28 molecular transducer activity#GO:0060089;lyase activity#GO:0016829;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;peptide receptor activity#GO:0001653;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;cell communication#GO:0007154;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanylate cyclase#PC00114;lyase#PC00144 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 IXOSC|EnsemblGenome=LOC115311310|UniProtKB=A0ACM8ENC1 A0ACM8ENC1 LOC115311310 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8038799|UniProtKB=A0ACM8EIM8 A0ACM8EIM8 LOC8038799 PTHR10362:SF85 HISTIDINE AMMONIA-LYASE HISTIDINE AMMONIA-LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 lyase#PC00144 IXOSC|EnsemblGenome=LOC8039143|UniProtKB=A0ACM8DKC7 A0ACM8DKC7 Rs1 PTHR47959:SF1 ATP-DEPENDENT RNA HELICASE RHLE-RELATED ATP-DEPENDENT RNA HELICASE MG308-RELATED RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8035747|UniProtKB=A0ACM8E7A3 A0ACM8E7A3 Mocs1 PTHR22960:SF0 MOLYBDOPTERIN COFACTOR SYNTHESIS PROTEIN A MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN 1 lyase activity#GO:0016829;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;carbon-carbon lyase activity#GO:0016830 macromolecule metabolic process#GO:0043170;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC121835053|UniProtKB=A0ACM8FSP2 A0ACM8FSP2 LOC121835053 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8035191|UniProtKB=A0ACM8DJR8 A0ACM8DJR8 mRpS14 PTHR19836:SF31 30S RIBOSOMAL PROTEIN S14 SMALL RIBOSOMAL SUBUNIT PROTEIN US14M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8029676|UniProtKB=A0ACM8F524 A0ACM8F524 LOC8029676 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121045826|UniProtKB=A0ACM8FB23 A0ACM8FB23 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121835472|UniProtKB=A0ACM8FVD2 A0ACM8FVD2 LOC121835472 PTHR46357:SF1 TRANSCRIPTIONAL REGULATOR ATRX CHROMATIN REMODELER ATRX DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488 chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;chromatin remodeling#GO:0006338;replication fork processing#GO:0031297;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8036860|UniProtKB=A0ACM8F007 A0ACM8F007 LOC8036860 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE 5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC120843661|UniProtKB=A0ACM8EXQ4 A0ACM8EXQ4 LOC120843661 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319489|UniProtKB=A0ACM8F3G0 A0ACM8F3G0 LOC120842893 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8052220|UniProtKB=A0ACM8DM38 A0ACM8DM38 LOC8052220 PTHR12027:SF101 WNT RELATED PROTEIN WNT-4 binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell fate commitment#GO:0045165;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 IXOSC|EnsemblGenome=LOC8037539|UniProtKB=A0ACM8E0W8 A0ACM8E0W8 LOC8037539 PTHR45695:SF44 LEUCOKININ RECEPTOR-RELATED SOMATOSTATIN RECEPTOR TYPE 3 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121836475|UniProtKB=A0ACM8G040 A0ACM8G040 LOC121836475 PTHR11177:SF409 CHITINASE CHITINASE 12-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033585|UniProtKB=A0ACM8F2I9 A0ACM8F2I9 LOC8033585 PTHR10696:SF55 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 cellular process#GO:0009987;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052207|UniProtKB=A0ACM8E5S1 A0ACM8E5S1 LOC8052207 PTHR10071:SF337 TRANSCRIPTION FACTOR GATA FAMILY MEMBER BOX A-BINDING FACTOR-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120846751|UniProtKB=A0ACM8FXM0 A0ACM8FXM0 LOC120846751 PTHR18952:SF278 CARBONIC ANHYDRASE CARBONIC ANHYDRASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 IXOSC|EnsemblGenome=LOC8039592|UniProtKB=A0ACM8EB24 A0ACM8EB24 Vha55 PTHR43389:SF4 V-TYPE PROTON ATPASE SUBUNIT B V-TYPE PROTON ATPASE SUBUNIT B regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;proton transmembrane transport#GO:1902600;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;cellular anatomical structure#GO:0110165;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;proton-transporting two-sector ATPase complex#GO:0016469;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;membrane#GO:0016020;cell periphery#GO:0071944 ATP synthase#PC00002;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8026592|UniProtKB=A0ACM8F6Y6 A0ACM8F6Y6 LOC8026592 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8037651|UniProtKB=A0ACM8DI78 A0ACM8DI78 PTHR31322:SF2 E3 UBIQUITIN-PROTEIN LIGASE TM129 E3 UBIQUITIN-PROTEIN LIGASE TM129 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120841837|UniProtKB=A0ACM8ESI6 A0ACM8ESI6 LOC120841837 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115325401|UniProtKB=A0ACM8EFK4 A0ACM8EFK4 LOC115325401 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=ISCI001867|UniProtKB=Q4PMD1 Q4PMD1 RpL38 PTHR10965:SF0 60S RIBOSOMAL PROTEIN L38 LARGE RIBOSOMAL SUBUNIT PROTEIN EL38 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121835470|UniProtKB=A0ACM8FTG2 A0ACM8FTG2 LOC121835470 PTHR11544:SF148 COLD SHOCK DOMAIN CONTAINING PROTEINS LD37574P nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8034253|UniProtKB=A0ACM8EB04 A0ACM8EB04 PTHR24403:SF67 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8028787|UniProtKB=A0ACM8EDG2 A0ACM8EDG2 LOC8028787 PTHR45701:SF3 SYNAPTOBREVIN FAMILY MEMBER SYNAPTOBREVIN protein binding#GO:0005515;SNAP receptor activity#GO:0005484;syntaxin binding#GO:0019905;binding#GO:0005488;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;vesicle organization#GO:0016050;transport#GO:0006810 intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150 Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986 IXOSC|EnsemblGenome=LOC8037077|UniProtKB=A0ACM8FH28 A0ACM8FH28 LOC8037077 PTHR13800:SF41 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 PROTEIN CED-11 monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC120836042|UniProtKB=A0ACM8F9B0 A0ACM8F9B0 LOC120836042 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841622|UniProtKB=A0ACM8ES58 A0ACM8ES58 LOC120841622 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8028581|UniProtKB=A0ACM8EM85 A0ACM8EM85 LOC8028581 PTHR15641:SF1 ELONGATOR COMPLEX PROTEIN 5 ELONGATOR COMPLEX PROTEIN 5 RNA binding#GO:0003723;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;elongator holoenzyme complex#GO:0033588;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8031710|UniProtKB=A0ACM8DIL2 A0ACM8DIL2 mRpS7 PTHR11205:SF19 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7M RNA binding#GO:0003723;structural molecule activity#GO:0005198;mRNA binding#GO:0003729;binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115314062|UniProtKB=A0ACM8FTE2 A0ACM8FTE2 LOC115314062 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121835824|UniProtKB=A0ACM8FVX6 A0ACM8FVX6 LOC121835824 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028988|UniProtKB=A0ACM8FWL1 A0ACM8FWL1 HSPBAP1 PTHR12461:SF43 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED HSPB1-ASSOCIATED PROTEIN 1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120837602|UniProtKB=A0ACM8EHA9 A0ACM8EHA9 LOC120837602 PTHR45797:SF3 RAD54-LIKE ATP-DEPENDENT HELICASE ATRX catalytic activity, acting on a nucleic acid#GO:0140640;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;transcription regulator activity#GO:0140110;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8030213|UniProtKB=A0ACM8EC00 A0ACM8EC00 LOC8030213 PTHR14191:SF3 PDZ DOMAIN CONTAINING PROTEIN GH04176P-RELATED protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121833199|UniProtKB=A0ACM8FJL9 A0ACM8FJL9 LOC121833199 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115317251|UniProtKB=A0ACM8F3C5 A0ACM8F3C5 LOC115317251 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053893|UniProtKB=A0ACM8FIK9 A0ACM8FIK9 LOC8053893 PTHR44157:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 DNAJ HOMOLOG SUBFAMILY C MEMBER 11 mitochondrion organization#GO:0007005;membrane organization#GO:0061024;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8031329|UniProtKB=A0ACM8DUT1 A0ACM8DUT1 LOC8031329 PTHR13561:SF20 DNA REPLICATION REGULATOR DPB11-RELATED DNA TOPOISOMERASE 2-BINDING PROTEIN 1 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8028222|UniProtKB=A0ACM8DRW0 A0ACM8DRW0 PTHR16047:SF7 RFWD3 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RFWD3 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115329081|UniProtKB=A0ACM8E8Y9 A0ACM8E8Y9 LOC115329081 PTHR11848:SF262 TGF-BETA FAMILY DAWDLE cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 IXOSC|EnsemblGenome=LOC120842767|UniProtKB=A0ACM8EVM6 A0ACM8EVM6 LOC120842767 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC121046950|UniProtKB=A0ACM8G4D0 A0ACM8G4D0 LOC121046950 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040438|UniProtKB=A0ACM8DTT7 A0ACM8DTT7 LOC8040438 PTHR43599:SF13 MULTIFUNCTIONAL PROTEIN ADE2 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;IMP metabolic process#GO:0046040;IMP biosynthetic process#GO:0006188;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121046929|UniProtKB=A0ACM8FFB5 A0ACM8FFB5 LOC121046929 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8038984|UniProtKB=A0ACM8FWP2 A0ACM8FWP2 LOC8038984 PTHR43615:SF1 PHOSPHOENOLPYRUVATE SYNTHASE-RELATED PHOSPHOENOLPYRUVATE SYNTHASE IXOSC|EnsemblGenome=LOC115327780|UniProtKB=A0ACM8EKZ7 A0ACM8EKZ7 LOC115327780 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8032308|UniProtKB=A0ACM8FT11 A0ACM8FT11 LOC8032308 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8034159|UniProtKB=A0ACM8DRH8 A0ACM8DRH8 LOC8034159 PTHR21522:SF32 PROTON CHANNEL OTOP PROTON CHANNEL OTOPLC proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120847826|UniProtKB=A0ACM8F3Y3 A0ACM8F3Y3 LOC120847826 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039435|UniProtKB=A0ACM8EED5 A0ACM8EED5 LOC8039435 PTHR11932:SF168 CULLIN CULLIN-1 structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Cul-1#P01239 IXOSC|EnsemblGenome=LOC8026391|UniProtKB=A0ACM8FDT8 A0ACM8FDT8 LOC8026391 PTHR31245:SF1 UBIQUITIN SYSTEM COMPONENT CUE PROTEIN UBIQUITIN SYSTEM COMPONENT CUE PROTEIN IXOSC|EnsemblGenome=LOC8030706|UniProtKB=A0ACM8DUQ5 A0ACM8DUQ5 l(2)k09848 PTHR16038:SF4 NOP SEVEN ASSOCIATED PROTEIN 1 WD REPEAT-CONTAINING PROTEIN 74 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8026872|UniProtKB=A0ACM8DIG9 A0ACM8DIG9 PTHR10218:SF362 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA O SUBUNIT catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898 heterotrimeric G-protein#PC00117;G-protein#PC00020 Opioid prodynorphin pathway#P05916>G-protein#P06002;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Enkephalin release#P05913>G-Protein (i)#P05974;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085 IXOSC|EnsemblGenome=LOC115313835|UniProtKB=A0ACM8EL09 A0ACM8EL09 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8051243|UniProtKB=A0ACM8E5G2 A0ACM8E5G2 TrpRS-m PTHR43766:SF5 TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL TRYPTOPHAN--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8036057|UniProtKB=A0ACM8DS15 A0ACM8DS15 LOC8036057 PTHR13252:SF9 F-BOX ONLY PROTEIN 28 F-BOX ONLY PROTEIN 28 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 IXOSC|EnsemblGenome=LOC120849564|UniProtKB=A0ACM8F8Y9 A0ACM8F8Y9 LOC120849564 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121836047|UniProtKB=A0ACM8FY61 A0ACM8FY61 LOC121836047 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120846354|UniProtKB=A0ACM8F244 A0ACM8F244 LOC120846354 PTHR21527:SF6 NUCLEOPORIN NUP35 NUCLEOPORIN NUP35 structural constituent of nuclear pore#GO:0017056;lipid binding#GO:0008289;structural molecule activity#GO:0005198;binding#GO:0005488;phospholipid binding#GO:0005543 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;nucleus organization#GO:0006997;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;organelle organization#GO:0006996;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;nucleocytoplasmic transport#GO:0006913;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nuclear pore organization#GO:0006999;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 IXOSC|EnsemblGenome=LOC8032596|UniProtKB=A0ACM8E022 A0ACM8E022 Gmppb PTHR22572:SF15 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE CATALYTIC SUBUNIT BETA transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;glycoprotein metabolic process#GO:0009100;nucleoside phosphate biosynthetic process#GO:1901293;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 IXOSC|EnsemblGenome=LOC8028089|UniProtKB=A0ACM8FK94 A0ACM8FK94 LOC8028089 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213 oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8026781|UniProtKB=A0ACM8FMA8 A0ACM8FMA8 LOC8026781 PTHR11042:SF197 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of translational initiation#GO:0006446;negative regulation of translation#GO:0017148;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121834286|UniProtKB=A0ACM8FNE8 A0ACM8FNE8 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310598|UniProtKB=A0ACM8DQ39 A0ACM8DQ39 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052113|UniProtKB=A0ACM8DTX9 A0ACM8DTX9 Fkbp59 PTHR46512:SF9 PEPTIDYLPROLYL ISOMERASE PEPTIDYLPROLYL ISOMERASE chaperone#PC00072 IXOSC|EnsemblGenome=LOC121835062|UniProtKB=A0ACM8FSR4 A0ACM8FSR4 LOC121835062 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8036079|UniProtKB=A0ACM8EJU2 A0ACM8EJU2 LOC8036079 PTHR13354:SF12 ROUND SPERMATID BASIC PROTEIN 1 LYSINE-SPECIFIC DEMETHYLASE 9 protein demethylase activity#GO:0140457;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8025977|UniProtKB=A0ACM8DGZ9 A0ACM8DGZ9 LOC8025977 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8040066|UniProtKB=A0ACM8DKI1 A0ACM8DKI1 LOC8040066 PTHR11205:SF18 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;binding#GO:0005488;mRNA binding#GO:0003729 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8035961|UniProtKB=A0ACM8G455 A0ACM8G455 LOC8035961 PTHR24243:SF242 G-PROTEIN COUPLED RECEPTOR CNMAMIDE RECEPTOR-RELATED neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121836040|UniProtKB=A0ACM8FWB6 A0ACM8FWB6 LOC121836040 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115327749|UniProtKB=A0ACM8G784 A0ACM8G784 LOC115327749 PTHR31569:SF7 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZSWIM1_3 RNASEH-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038813|UniProtKB=A0ACM8DGY9 A0ACM8DGY9 LOC8038813 PTHR22776:SF102 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RH30783P regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121838125|UniProtKB=A0ACM8G7W3 A0ACM8G7W3 LOC121838125 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115328051|UniProtKB=A0ACM8E8L9 A0ACM8E8L9 LOC115328051 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC121047208|UniProtKB=A0ACM8FRL6 A0ACM8FRL6 Vdup1 PTHR11188:SF179 ARRESTIN DOMAIN CONTAINING PROTEIN FI21816P1 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120843910|UniProtKB=A0ACM8EX43 A0ACM8EX43 LOC120843910 PTHR10131:SF166 TNF RECEPTOR ASSOCIATED FACTOR RING FINGER PROTEIN 151 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8030843|UniProtKB=A0ACM8DZL6 A0ACM8DZL6 LOC8030843 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8038865|UniProtKB=A0ACM8FVW6 A0ACM8FVW6 BBS4 PTHR44186:SF1 FAMILY NOT NAMED BBSOME COMPLEX MEMBER BBS4 IXOSC|EnsemblGenome=LOC8036442|UniProtKB=A0ACM8E070 A0ACM8E070 RpS13 PTHR11885:SF6 RIBOSOMAL PROTEIN S15P/S13E SMALL RIBOSOMAL SUBUNIT PROTEIN US15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytosolic ribosome#GO:0022626;organelle lumen#GO:0043233;ribosome#GO:0005840;small-subunit processome#GO:0032040;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120842300|UniProtKB=A0ACM8ETF9 A0ACM8ETF9 LOC120842300 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115332826|UniProtKB=A0ACM8G4J1 A0ACM8G4J1 LOC115332826 PTHR43767:SF1 LONG-CHAIN-FATTY-ACID--COA LIGASE NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120839482|UniProtKB=A0ACM8EMX6 A0ACM8EMX6 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120843986|UniProtKB=A0ACM8EXE2 A0ACM8EXE2 LOC120843986 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115324224|UniProtKB=A0ACM8E4L6 A0ACM8E4L6 LOC115324224 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115311524|UniProtKB=A0ACM8F865 A0ACM8F865 Wnt2 PTHR12027:SF112 WNT RELATED PROTEIN WNT-2 cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;Wnt signaling pathway#GO:0016055;system development#GO:0048731;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;multicellular organismal process#GO:0032501;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;developmental process#GO:0032502;neurogenesis#GO:0022008;positive regulation of MAPK cascade#GO:0043410;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;signaling#GO:0023052;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;positive regulation of JNK cascade#GO:0046330;animal gross anatomical part developmental process#GO:0160108;regulation of intracellular signal transduction#GO:1902531;cell fate commitment#GO:0045165;positive regulation of signaling#GO:0023056;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;nervous system development#GO:0007399;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;regulation of JNK cascade#GO:0046328 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 IXOSC|EnsemblGenome=LOC8053882|UniProtKB=A0ACM8DLP5 A0ACM8DLP5 LOC8053882 PTHR16521:SF4 TYPE-1 ANGIOTENSIN II RECEPTOR-ASSOCIATED PROTEIN FI19011P1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC120845392|UniProtKB=A0ACM8F006 A0ACM8F006 LOC120845392 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120838740|UniProtKB=A0ACM8EKD3 A0ACM8EKD3 LOC120838740 PTHR16089:SF40 REST COREPRESSOR COREST PROTEIN-RELATED SUPPRESSOR OF ACTIVATED EGL-4 PROTEIN 1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120841830|UniProtKB=A0ACM8ETL4 A0ACM8ETL4 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034379|UniProtKB=A0ACM8EB45 A0ACM8EB45 Unc-76 PTHR12394:SF12 ZYGIN LD08195P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;axon#GO:0030424 IXOSC|EnsemblGenome=LOC8024036|UniProtKB=A0ACM8FJC9 A0ACM8FJC9 LOC8024036 PTHR24252:SF32 ACROSIN-RELATED SERINE PROTEASE 33 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120837696|UniProtKB=A0ACM8EIS0 A0ACM8EIS0 LOC120837700 PTHR46569:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRAIP E3 UBIQUITIN-PROTEIN LIGASE TRAIP catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;protein modification by small protein conjugation#GO:0032446;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;replication fork processing#GO:0031297;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8029327|UniProtKB=A0ACM8G1L7 A0ACM8G1L7 LOC8029327 PTHR15711:SF25 RAP GTPASE-ACTIVATING PROTEIN RADISH, ISOFORM I enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC8029132|UniProtKB=A0ACM8FKA0 A0ACM8FKA0 LOC8029132 PTHR13023:SF3 APYRASE SOLUBLE CALCIUM-ACTIVATED NUCLEOTIDASE 1 hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;membrane#GO:0016020 hydrolase#PC00121;nucleotide phosphatase#PC00173 IXOSC|EnsemblGenome=LOC8028283|UniProtKB=A0ACM8E475 A0ACM8E475 LOC8028283 PTHR13817:SF73 TITIN FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN structural protein#PC00211 IXOSC|EnsemblGenome=LOC115332212|UniProtKB=A0ACM8EED9 A0ACM8EED9 LOC115332212 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC8034763|UniProtKB=A0ACM8DVQ9 A0ACM8DVQ9 LOC8034763 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;binding#GO:0005488;catalytic activity#GO:0003824;small molecule binding#GO:0036094 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8023509|UniProtKB=A0ACM8DH78 A0ACM8DH78 mRpL18 PTHR12899:SF23 39S RIBOSOMAL PROTEIN L18, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL18M RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843 establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;localization#GO:0051179;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120843578|UniProtKB=A0ACM8EXI3 A0ACM8EXI3 LOC120843578 PTHR33147:SF39 DEFENSIN-LIKE PROTEIN 1 DEFENSIN-LIKE PROTEIN 98 response to stimulus#GO:0050896;defense response#GO:0006952;response to stress#GO:0006950 antimicrobial response protein#PC00051 IXOSC|EnsemblGenome=LOC8050449|UniProtKB=A0ACM8DLC2 A0ACM8DLC2 TH1 PTHR12144:SF0 NEGATIVE ELONGATION FACTOR D NEGATIVE ELONGATION FACTOR C_D RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 IXOSC|EnsemblGenome=LOC115323944|UniProtKB=A0ACM8EUX3 A0ACM8EUX3 LOC115323944 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120846350|UniProtKB=A0ACM8F317 A0ACM8F317 LOC120846350 PTHR10803:SF3 ARSENICAL PUMP-DRIVING ATPASE ARSENITE-TRANSLOCATING ATPASE ATPASE GET3 hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043 endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 transporter#PC00227 IXOSC|EnsemblGenome=LOC8027513|UniProtKB=A0ACM8EER7 A0ACM8EER7 LOC8027513 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC121833251|UniProtKB=A0ACM8FJH0 A0ACM8FJH0 LOC8029505 PTHR45640:SF26 HEAT SHOCK PROTEIN HSP-12.2-RELATED RE23625P macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;response to heat#GO:0009408;protein refolding#GO:0042026;protein metabolic process#GO:0019538;protein folding#GO:0006457;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 VEGF signaling pathway#P00056>HSP27#P01412;Angiogenesis#P00005>HSP27#P00231 IXOSC|EnsemblGenome=LOC8033579|UniProtKB=A0ACM8FKG8 A0ACM8FKG8 LOC8033579 PTHR45080:SF8 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE 1 ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cell adhesion#GO:0007155;cell junction organization#GO:0034330;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043 cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;axon#GO:0030424 IXOSC|EnsemblGenome=LOC115318733|UniProtKB=A0ACM8DZ49 A0ACM8DZ49 LOC115318733 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850041|UniProtKB=A0ACM8F9A7 A0ACM8F9A7 LOC120850041 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115330541|UniProtKB=A0ACM8EAY6 A0ACM8EAY6 LOC115330541 PTHR31952:SF1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 CB1 CANNABINOID RECEPTOR-INTERACTING PROTEIN 1 signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC120846581|UniProtKB=A0ACM8FHF1 A0ACM8FHF1 LOC120846581 PTHR46199:SF3 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;signaling#GO:0023052;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of biological process#GO:0050789;Rho protein signal transduction#GO:0007266;cytoskeleton-dependent cytokinesis#GO:0061640;nuclear division#GO:0000280;cytokinesis#GO:0000910;cellular component assembly#GO:0022607;spindle elongation#GO:0051231;intracellular signaling cassette#GO:0141124;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;chromosome segregation#GO:0007059;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cell division#GO:0051301;cellular response to stimulus#GO:0051716;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;organelle assembly#GO:0070925;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;spindle organization#GO:0007051;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;midbody#GO:0030496;cleavage furrow#GO:0032154;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;spindle#GO:0005819;cytoskeleton#GO:0005856;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;plasma membrane#GO:0005886;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC8039168|UniProtKB=A0ACM8EBL2 A0ACM8EBL2 Baldspot PTHR11157:SF17 FATTY ACID ACYL TRANSFERASE-RELATED VERY LONG CHAIN FATTY ACID ELONGASE 6 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115315228|UniProtKB=A0ACM8EKY7 A0ACM8EKY7 LOC115315228 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025484|UniProtKB=A0ACM8DJB1 A0ACM8DJB1 LOC8025484 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8037471|UniProtKB=A0ACM8FSM3 A0ACM8FSM3 LOC8037471 PTHR13723:SF323 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 6 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121834652|UniProtKB=A0ACM8FRI1 A0ACM8FRI1 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115326205|UniProtKB=A0ACM8EK75 A0ACM8EK75 LOC115326205 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 RNA metabolic process#GO:0016070;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 hydrolase#PC00121;deaminase#PC00088;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120845944|UniProtKB=A0ACM8F0U9 A0ACM8F0U9 LOC120845944 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120842241|UniProtKB=A0ACM8ETC0 A0ACM8ETC0 LOC120842241 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 IXOSC|EnsemblGenome=LOC121834166|UniProtKB=A0ACM8FPL4 A0ACM8FPL4 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8043475|UniProtKB=A0ACM8FSH0 A0ACM8FSH0 LOC8043475 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8035839|UniProtKB=A0ACM8FU09 A0ACM8FU09 LOC8035839 PTHR18945:SF835 NEUROTRANSMITTER GATED ION CHANNEL LIGAND-GATED ION CHANNEL ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;neurotransmitter receptor activity#GO:0030594;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267 animal gross anatomical part developmental process#GO:0160108;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;signaling#GO:0023052;synapse assembly#GO:0007416;chloride transport#GO:0006821;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;nervous system development#GO:0007399;monoatomic anion transmembrane transport#GO:0098656;cellular component assembly#GO:0022607;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;system development#GO:0048731;anatomical structure development#GO:0048856;chloride transmembrane transport#GO:1902476;cell communication#GO:0007154;localization#GO:0051179;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;cell junction organization#GO:0034330;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;multicellular organismal process#GO:0032501 cell junction#GO:0030054;signaling receptor complex#GO:0043235;neuron projection membrane#GO:0032589;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell projection membrane#GO:0031253;dendrite#GO:0030425;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;postsynapse#GO:0098794 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8041765|UniProtKB=A0ACM8F484 A0ACM8F484 LOC8041765 PTHR24230:SF75 G-PROTEIN COUPLED RECEPTOR ALLATOSTATIN A RECEPTOR 2, ISOFORM A G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121838320|UniProtKB=A0ACM8G7F3 A0ACM8G7F3 LOC121838320 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121048545|UniProtKB=A0ACM8FIP0 A0ACM8FIP0 LOC121048545 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845319|UniProtKB=A0ACM8EZX7 A0ACM8EZX7 LOC120845319 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121833944|UniProtKB=A0ACM8FNV9 A0ACM8FNV9 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;hexose metabolic process#GO:0019318;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115308443|UniProtKB=A0ACM8DMK0 A0ACM8DMK0 LOC115308443 PTHR42760:SF133 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120841637|UniProtKB=A0ACM8FK55 A0ACM8FK55 LOC120841637 PTHR11690:SF248 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8051233|UniProtKB=A0ACM8DLE2 A0ACM8DLE2 LOC8051233 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115329635|UniProtKB=A0ACM8ETA3 A0ACM8ETA3 LOC115329635 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121046510|UniProtKB=A0ACM8FEB2 A0ACM8FEB2 LOC121046510 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8053019|UniProtKB=A0ACM8DLL1 A0ACM8DLL1 LOC8053019 PTHR18884:SF130 SEPTIN SEPTIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;localization#GO:0051179;regulation of secretion#GO:0051046;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;biological regulation#GO:0065007;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of localization#GO:0032879;intracellular protein localization#GO:0008104;regulation of transport#GO:0051049 cell cortex#GO:0005938;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;presynapse#GO:0098793;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;secretory vesicle#GO:0099503;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 IXOSC|EnsemblGenome=LOC8024746|UniProtKB=A0ACM8EJP8 A0ACM8EJP8 LOC8024746 PTHR24264:SF54 TRYPSIN-RELATED CHITINASE catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115318826|UniProtKB=A0ACM8DYY3 A0ACM8DYY3 LOC115318826 PTHR23236:SF120 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC TRANSLATION INITIATION FACTOR 4H RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8030265|UniProtKB=A0ACM8DZL3 A0ACM8DZL3 LOC8030265 PTHR19879:SF1 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;peptidase complex#GO:1905368;catalytic complex#GO:1902494;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;SAGA complex#GO:0000124;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8035104|UniProtKB=A0ACM8DJN4 A0ACM8DJN4 LOC8035104 PTHR32251:SF17 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE STEROID 5-ALPHA REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120846360|UniProtKB=A0ACM8F332 A0ACM8F332 LOC120846360 PTHR45700:SF2 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3C catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 IXOSC|EnsemblGenome=LOC121835363|UniProtKB=A0ACM8FSV9 A0ACM8FSV9 LOC121835363 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115326757|UniProtKB=A0ACM8FTW3 A0ACM8FTW3 LOC115326757 PTHR13005:SF4 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8027759|UniProtKB=A0ACM8DJD5 A0ACM8DJD5 LOC8027759 PTHR11835:SF60 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 generation of precursor metabolites and energy#GO:0006091;alcohol metabolic process#GO:0006066;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8023601|UniProtKB=A0ACM8FWV8 A0ACM8FWV8 LOC8023601 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120841611|UniProtKB=A0ACM8ET33 A0ACM8ET33 LOC120841611 PTHR47760:SF1 G-PROTEIN COUPLED RECEPTOR B0563.6-LIKE PROTEIN-RELATED G PROTEIN-COUPLED RECEPTOR B0563.6-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120840974|UniProtKB=A0ACM8ERP9 A0ACM8ERP9 LOC120840974 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8033205|UniProtKB=A0ACM8EB74 A0ACM8EB74 Ifrd1 PTHR12354:SF1 INTERFERON-RELATED DEVELOPMENTAL REGULATOR INTERFERON-RELATED DEVELOPMENTAL REGULATOR 1 IXOSC|EnsemblGenome=LOC115329101|UniProtKB=A0ACM8G1Z1 A0ACM8G1Z1 LOC115329101 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC115321374|UniProtKB=A0ACM8E1Q6 A0ACM8E1Q6 LOC115321374 PTHR45745:SF1 PHOSPHOMANNOMUTASE 45A PHOSPHOGLUCOMUTASE 2A-RELATED intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;small molecule biosynthetic process#GO:0044283;purine nucleoside metabolic process#GO:0042278;nucleobase-containing compound biosynthetic process#GO:0034654;purine-containing compound biosynthetic process#GO:0072522;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 mutase#PC00160;metabolite interconversion enzyme#PC00262;isomerase#PC00135 IXOSC|EnsemblGenome=LOC115322753|UniProtKB=A0ACM8F1H9 A0ACM8F1H9 LOC115322753 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8043863|UniProtKB=A0ACM8E7P5 A0ACM8E7P5 LOC8043863 PTHR11588:SF501 TUBULIN TUBULIN ALPHA CHAIN nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080 cytoskeletal protein#PC00085;tubulin#PC00228 IXOSC|EnsemblGenome=LOC120845942|UniProtKB=A0ACM8F111 A0ACM8F111 LOC120845942 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023270|UniProtKB=A0ACM8DYW1 A0ACM8DYW1 LOC8023270 PTHR22883:SF40 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;catalytic activity, acting on a protein#GO:0140096 regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;protein localization to cell periphery#GO:1990778;protein targeting to membrane#GO:0006612;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;localization#GO:0051179;cellular localization#GO:0051641;regulation of biological process#GO:0050789;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;regulation of cell communication#GO:0010646;protein targeting#GO:0006605;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8051977|UniProtKB=A0ACM8DLG9 A0ACM8DLG9 LOC8051977 PTHR17614:SF14 ZINC FINGER-CONTAINING G PATCH DOMAIN-CONTAINING PROTEIN 8-LIKE ISOFORM X5 IXOSC|EnsemblGenome=LOC8032136|UniProtKB=A0ACM8DTK4 A0ACM8DTK4 LOC8032136 PTHR31938:SF4 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 NUCLEAR SPECKLE SPLICING REGULATORY PROTEIN 1 IXOSC|EnsemblGenome=LOC115324388|UniProtKB=A0ACM8ELW1 A0ACM8ELW1 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836676|UniProtKB=A0ACM8EG59 A0ACM8EG59 LOC120836676 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8032246|UniProtKB=A0ACM8DZV0 A0ACM8DZV0 LOC8032246 PTHR45888:SF5 HL01030P-RELATED D4, ISOFORM A transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8037694|UniProtKB=A0ACM8EAR4 A0ACM8EAR4 LOC8037694 PTHR10529:SF377 AP COMPLEX SUBUNIT MU ADAPTOR PROTEIN COMPLEX 2, MU SUBUNIT, ISOFORM A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 clathrin-dependent endocytosis#GO:0072583;endocytosis#GO:0006897;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898 cell periphery#GO:0071944;vesicle membrane#GO:0012506;cytosol#GO:0005829;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;plasma membrane#GO:0005886;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;vesicle coat#GO:0030120;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;coated membrane#GO:0048475 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8033793|UniProtKB=A0ACM8DIC0 A0ACM8DIC0 LOC8033793 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120850335|UniProtKB=A0ACM8F9S8 A0ACM8F9S8 LOC120850335 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8024476|UniProtKB=A0ACM8EAB4 A0ACM8EAB4 Rich PTHR22746:SF11 RAB6A-GEF COMPLEX PARTNER PROTEIN 1 GUANINE NUCLEOTIDE EXCHANGE FACTOR SUBUNIT RIC1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cytosolic transport#GO:0016482;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cellular localization#GO:0051641;neuron development#GO:0048666;axonogenesis#GO:0007409;protein transport#GO:0015031;neuron projection development#GO:0031175;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;intracellular protein transport#GO:0006886;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;protein localization to synapse#GO:0035418;endosomal transport#GO:0016197;cell projection morphogenesis#GO:0048858;protein localization to cell junction#GO:1902414;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;axon development#GO:0061564;axon guidance#GO:0007411;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;transport#GO:0006810;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008 cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;guanyl-nucleotide exchange factor complex#GO:0032045;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120839105|UniProtKB=A0ACM8ELI7 A0ACM8ELI7 LOC120839105 PTHR24070:SF462 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SMALL MONOMERIC GTPASE hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cell communication#GO:0007154;regulation of cell motility#GO:2000145;intracellular signal transduction#GO:0035556;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;negative regulation of cell migration#GO:0030336;regulation of cell migration#GO:0030334;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;negative regulation of locomotion#GO:0040013;small GTPase-mediated signal transduction#GO:0007264;negative regulation of cell motility#GO:2000146 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906 IXOSC|EnsemblGenome=LOC8033367|UniProtKB=A0ACM8EEY5 A0ACM8EEY5 LOC8033367 PTHR42884:SF39 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED NEUROENDOCRINE CONVERTASE 1 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;proteolysis#GO:0006508;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;peptide hormone processing#GO:0016486;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;neuron projection#GO:0043005;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 serine protease#PC00203 Alzheimer disease-presenilin pathway#P00004>Furin#P00157;Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105 IXOSC|EnsemblGenome=LOC121833151|UniProtKB=A0ACM8FKL1 A0ACM8FKL1 LOC121833151 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120844083|UniProtKB=A0ACM8EXV5 A0ACM8EXV5 LOC120844083 PTHR37162:SF14 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZMYM1-LIKE RNASE-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847342|UniProtKB=A0ACM8F4R0 A0ACM8F4R0 LOC120847342 PTHR12553:SF49 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 ZINC PHOSPHODIESTERASE ELAC PROTEIN 2 nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;gene expression#GO:0010467;mitochondrial RNA 3'-end processing#GO:0000965;tRNA 3'-end processing#GO:0042780;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC115329042|UniProtKB=A0ACM8FZ18 A0ACM8FZ18 LOC115329042 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121046968|UniProtKB=A0ACM8FG79 A0ACM8FG79 LOC121046968 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836092|UniProtKB=A0ACM8F4H0 A0ACM8F4H0 LOC8030709 PTHR10484:SF162 HISTONE H4 HISTONE H4-LIKE PROTEIN TYPE G structural molecule activity#GO:0005198 nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;protein-DNA complex assembly#GO:0065004;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115309771|UniProtKB=A0ACM8DNZ4 A0ACM8DNZ4 LOC115309771 PTHR21661:SF35 EPOXIDE HYDROLASE 1-RELATED EPOXIDE HYDROLASE hydrolase activity#GO:0016787;ether hydrolase activity#GO:0016803;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120848649|UniProtKB=A0ACM8F749 A0ACM8F749 LOC120848649 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051551|UniProtKB=A0ACM8G3C9 A0ACM8G3C9 LOC8051551 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE peptidase activity#GO:0008233;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120837132|UniProtKB=A0ACM8EGM4 A0ACM8EGM4 LOC120837132 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115330552|UniProtKB=A0ACM8EIS7 A0ACM8EIS7 LOC115330552 PTHR13121:SF0 GPI TRANSAMIDASE COMPONENT PIG-U GPI-ANCHOR TRANSAMIDASE COMPONENT PIGU macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;GPI anchored protein biosynthesis#GO:0180046;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;peptidase complex#GO:1905368;caspase complex#GO:0008303;cytoplasm#GO:0005737;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115330559|UniProtKB=A0ACM8EBE0 A0ACM8EBE0 LOC115330559 PTHR13172:SF5 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9B MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM9 molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 membrane-enclosed lumen#GO:0031974;mitochondrial envelope#GO:0005740;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;mitochondrial intermembrane space#GO:0005758;organelle lumen#GO:0043233;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8052115|UniProtKB=A0ACM8DU84 A0ACM8DU84 mtDNA-helicase PTHR12873:SF7 T7-LIKE MITOCHONDRIAL DNA HELICASE TWINKLE MTDNA HELICASE catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;mitochondrial DNA metabolic process#GO:0032042;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA replication#GO:0006260;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC115309320|UniProtKB=A0ACM8DNI6 A0ACM8DNI6 LOC115309320 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115328527|UniProtKB=A0ACM8F5I9 A0ACM8F5I9 LOC115328527 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8034102|UniProtKB=A0ACM8DIY7 A0ACM8DIY7 LOC8034102 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 IXOSC|EnsemblGenome=LOC120842142|UniProtKB=A0ACM8ET54 A0ACM8ET54 LOC120842142 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8025804|UniProtKB=A0ACM8DGF0 A0ACM8DGF0 LOC8025804 PTHR22691:SF8 YEAST SPT2-RELATED PROTEIN SPT2 HOMOLOG protein binding#GO:0005515;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;histone binding#GO:0042393 nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;transcription by RNA polymerase I#GO:0006360;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120838293|UniProtKB=A0ACM8G7R5 A0ACM8G7R5 Drak PTHR24342:SF12 SERINE/THREONINE-PROTEIN KINASE 17 DEATH-ASSOCIATED PROTEIN KINASE RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115327431|UniProtKB=A0ACM8F9T2 A0ACM8F9T2 LOC115327431 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8031081|UniProtKB=A0ACM8DSV1 A0ACM8DSV1 LOC8031081 PTHR10857:SF106 COPINE NICOTINIC RECEPTOR-ASSOCIATED PROTEIN 1 phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 response to chemical#GO:0042221;response to calcium ion#GO:0051592;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to metal ion#GO:0010038;cellular response to chemical stimulus#GO:0070887 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC8051502|UniProtKB=A0ACM8DQ59 A0ACM8DQ59 LOC8051502 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8041318|UniProtKB=A0ACM8EL66 A0ACM8EL66 LOC8041318 PTHR11544:SF148 COLD SHOCK DOMAIN CONTAINING PROTEINS LD37574P nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8026043|UniProtKB=A0ACM8EUX8 A0ACM8EUX8 LOC8026043 PTHR46609:SF6 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN EXONUCLEASE, PHAGE-TYPE_RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120845981|UniProtKB=A0ACM8F172 A0ACM8F172 LOC120845981 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838167|UniProtKB=A0ACM8G8C0 A0ACM8G8C0 LOC121838167 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115330988|UniProtKB=A0ACM8EBQ4 A0ACM8EBQ4 LOC115330988 PTHR43205:SF5 PROSTAGLANDIN REDUCTASE PROSTAGLANDIN REDUCTASE 2 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;icosanoid metabolic process#GO:0006690;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;prostaglandin metabolic process#GO:0006693 reductase#PC00198 IXOSC|EnsemblGenome=LOC115312795|UniProtKB=A0ACM8EUQ8 A0ACM8EUQ8 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313782|UniProtKB=A0ACM8FBN1 A0ACM8FBN1 LOC120850747 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115311997|UniProtKB=A0ACM8F0A6 A0ACM8F0A6 LOC115311997 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8023859|UniProtKB=A0ACM8FC97 A0ACM8FC97 LOC8023859 PTHR45713:SF6 FTP DOMAIN-CONTAINING PROTEIN F5_8 TYPE C DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053528|UniProtKB=A0ACM8DL73 A0ACM8DL73 LOC8053528 PTHR28532:SF1 GEO13458P1 LTO1 MATURATION FACTOR OF ABCE1 IXOSC|EnsemblGenome=LOC120836574|UniProtKB=A0ACM8EF01 A0ACM8EF01 LOC120836574 PTHR12307:SF36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT carbohydrate binding#GO:0030246;protein binding#GO:0005515;protein phosphatase binding#GO:0019903;phosphatase binding#GO:0019902;binding#GO:0005488;polysaccharide binding#GO:0030247;enzyme binding#GO:0019899 regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of carbohydrate metabolic process#GO:0006109;regulation of glycogen biosynthetic process#GO:0005979;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of carbohydrate biosynthetic process#GO:0043255;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8023939|UniProtKB=A0ACM8DMJ5 A0ACM8DMJ5 LOC8023939 PTHR46218:SF4 LASP LIM AND SH3 DOMAIN PROTEIN LASP binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115329030|UniProtKB=A0ACM8ES97 A0ACM8ES97 LOC115329030 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC binding#GO:0005488;chromatin binding#GO:0003682 regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8026160|UniProtKB=A0ACM8FMS5 A0ACM8FMS5 LOC8026160 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115321591|UniProtKB=A0ACM8F5P0 A0ACM8F5P0 LOC115321591 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8050608|UniProtKB=A0ACM8EWX5 A0ACM8EWX5 LOC8050608 PTHR12011:SF477 ADHESION G-PROTEIN COUPLED RECEPTOR ADHESION G PROTEIN-COUPLED RECEPTOR E2-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8034312|UniProtKB=A0ACM8FVA8 A0ACM8FVA8 LOC8034312 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;binding#GO:0005488;tetrapyrrole binding#GO:0046906 response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;steroid metabolic process#GO:0008202;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8032590|UniProtKB=A0ACM8DJJ0 A0ACM8DJJ0 Rab23 PTHR24073:SF209 DRAB5-RELATED RAS-RELATED PROTEIN RAB-23 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;intracellular transport#GO:0046907;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of protein localization#GO:0045184;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;organelle assembly#GO:0070925;catabolic process#GO:0009056;cellular component organization#GO:0016043 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505 G-protein#PC00020;small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120840733|UniProtKB=A0ACM8EPE2 A0ACM8EPE2 sicily PTHR21181:SF13 ER membrane protein complex subunit 5-related NADH DEHYDROGENASE (UBIQUINONE) COMPLEX I, ASSEMBLY FACTOR 6 IXOSC|EnsemblGenome=LOC115330520|UniProtKB=A0ACM8F438 A0ACM8F438 LOC115330520 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8036140|UniProtKB=A0ACM8E2E3 A0ACM8E2E3 LOC8036140 PTHR10680:SF39 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 IXOSC|EnsemblGenome=LOC8023621|UniProtKB=A0ACM8FTZ7 A0ACM8FTZ7 ds PTHR24026:SF142 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN-23 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 IXOSC|EnsemblGenome=LOC8039790|UniProtKB=A0ACM8FTD6 A0ACM8FTD6 LOC8039790 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8034990|UniProtKB=A0ACM8FT83 A0ACM8FT83 LOC8034990 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121833862|UniProtKB=A0ACM8FN52 A0ACM8FN52 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;response to stimulus#GO:0050896;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;nucleobase-containing compound metabolic process#GO:0006139;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8039004|UniProtKB=A0ACM8FB33 A0ACM8FB33 LOC8039004 PTHR11211:SF40 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN ARAUCAN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8040375|UniProtKB=A0ACM8EAE2 A0ACM8EAE2 LOC8040375 PTHR46990:SF2 GLUTAREDOXIN DOMAIN-CONTAINING CYSTEINE-RICH PROTEIN 1 GLUTAREDOXIN AND CYSTEINE-RICH DOMAIN-CONTAINING 1 B-RELATED oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043297|UniProtKB=A0ACM8FS98 A0ACM8FS98 LOC8043297 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8042591|UniProtKB=A0ACM8EBX3 A0ACM8EBX3 LOC8042591 PTHR20935:SF0 PHOSPHOGLYCERATE MUTASE-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE PGAM5, MITOCHONDRIAL phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 positive regulation of organelle organization#GO:0010638;regulation of anatomical structure morphogenesis#GO:0022603;positive regulation of cellular component organization#GO:0051130;positive regulation of developmental process#GO:0051094;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;regulation of organelle organization#GO:0033043;positive regulation of biological process#GO:0048518;regulation of mitochondrion organization#GO:0010821;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 mutase#PC00160;isomerase#PC00135 IXOSC|EnsemblGenome=LOC115331804|UniProtKB=A0ACM8F0C8 A0ACM8F0C8 LOC115331804 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120847507|UniProtKB=A0ACM8F463 A0ACM8F463 LOC120847507 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120841322|UniProtKB=A0ACM8ERJ6 A0ACM8ERJ6 LOC120841322 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115323991|UniProtKB=A0ACM8ENK8 A0ACM8ENK8 LOC115323991 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=ISCI008252|UniProtKB=Q5Q995 Q5Q995 PTHR32001:SF1 KERATINOCYTE-ASSOCIATED PROTEIN 2 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT KCP2 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 IXOSC|EnsemblGenome=LOC121047703|UniProtKB=A0ACM8FGR9 A0ACM8FGR9 LOC121047703 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039895|UniProtKB=A0ACM8FMC1 A0ACM8FMC1 LOC8039895 PTHR10293:SF74 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-3 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;monoatomic ion homeostasis#GO:0050801;cellular component assembly#GO:0022607;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;cellular component organization or biogenesis#GO:0071840;intracellular monoatomic ion homeostasis#GO:0006873;cellular component organization#GO:0016043;homeostatic process#GO:0042592;iron-sulfur cluster assembly#GO:0016226;intracellular iron ion homeostasis#GO:0006879;inorganic ion homeostasis#GO:0098771 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8043522|UniProtKB=A0ACM8E3K8 A0ACM8E3K8 LOC8043522 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115324513|UniProtKB=A0ACM8E421 A0ACM8E421 LOC115324513 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327550|UniProtKB=A0ACM8FFT2 A0ACM8FFT2 LOC115327550 PTHR18916:SF88 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;microtubule end#GO:1990752;cell cortex#GO:0005938;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;cell periphery#GO:0071944;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8032071|UniProtKB=A0ACM8EL05 A0ACM8EL05 LOC8032071 PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC121837829|UniProtKB=A0ACM8G5C3 A0ACM8G5C3 LOC121837829 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329595|UniProtKB=A0ACM8EB95 A0ACM8EB95 LOC115329595 PTHR11717:SF7 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8027368|UniProtKB=A0ACM8DUT7 A0ACM8DUT7 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8036753|UniProtKB=A0ACM8DHP2 A0ACM8DHP2 LOC8036753 PTHR39069:SF11 ECDYSONE-INDUCIBLE GENE E1, ISOFORM A EB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024183|UniProtKB=A0ACM8DMY1 A0ACM8DMY1 LOC8024183 PTHR15742:SF5 GIRDIN GIRDIN protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 IXOSC|EnsemblGenome=LOC8027919|UniProtKB=A0ACM8E5B0 A0ACM8E5B0 LOC8027919 PTHR10183:SF379 CALPAIN CALPAIN-A-RELATED cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 IXOSC|EnsemblGenome=LOC121836807|UniProtKB=A0ACM8G073 A0ACM8G073 LOC121836807 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308176|UniProtKB=A0ACM8E1L2 A0ACM8E1L2 su(f) PTHR19980:SF0 RNA CLEAVAGE STIMULATION FACTOR CLEAVAGE STIMULATION FACTOR SUBUNIT 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120847644|UniProtKB=A0ACM8G3R4 A0ACM8G3R4 LOC120847644 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837026|UniProtKB=A0ACM8G1B9 A0ACM8G1B9 LOC121837026 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8027215|UniProtKB=A0ACM8DIU4 A0ACM8DIU4 LOC8027215 PTHR42643:SF49 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120847442|UniProtKB=A0ACM8F4Z1 A0ACM8F4Z1 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115310136|UniProtKB=A0ACM8DPB6 A0ACM8DPB6 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8032139|UniProtKB=A0ACM8FW53 A0ACM8FW53 LOC8032139 PTHR14429:SF22 FIBROSIN FAMILY MEMBER AUTISM SUSCEPTIBILITY GENE 2 PROTEIN HOMOLOG ISOFORM X1 IXOSC|EnsemblGenome=LOC8025113|UniProtKB=A0ACM8F5F7 A0ACM8F5F7 LOC8025113 PTHR42737:SF2 GLUTATHIONE REDUCTASE GLUTATHIONE REDUCTASE, MITOCHONDRIAL ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;disulfide oxidoreductase activity#GO:0015036;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;response to stress#GO:0006950;sulfur compound metabolic process#GO:0006790;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;metabolic process#GO:0008152;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stimulus#GO:0051716;modified amino acid metabolic process#GO:0006575;homeostatic process#GO:0042592;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;glutathione metabolic process#GO:0006749 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8037696|UniProtKB=A0ACM8DK49 A0ACM8DK49 LOC8037696 PTHR10064:SF0 60S RIBOSOMAL PROTEIN L22 LARGE RIBOSOMAL SUBUNIT PROTEIN EL22 structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8027040|UniProtKB=A0ACM8EJZ6 A0ACM8EJZ6 PTHR22950:SF652 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 IXOSC|EnsemblGenome=LOC115309987|UniProtKB=A0ACM8DP68 A0ACM8DP68 LOC115309987 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835985|UniProtKB=A0ACM8FWM9 A0ACM8FWM9 LOC121835985 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120841168|UniProtKB=A0ACM8ES45 A0ACM8ES45 LOC120841168 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035797|UniProtKB=A0ACM8DM99 A0ACM8DM99 Mau2 PTHR21394:SF0 MAU2 CHROMATID COHESION FACTOR HOMOLOG MAU2 CHROMATID COHESION FACTOR HOMOLOG catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;mitotic sister chromatid cohesion#GO:0007064;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115315625|UniProtKB=A0ACM8DVH6 A0ACM8DVH6 LOC115315625 PTHR11453:SF127 ANION EXCHANGE PROTEIN SOLUTE CARRIER FAMILY 4 MEMBER 11 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106 transport#GO:0006810;chemical homeostasis#GO:0048878;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;homeostatic process#GO:0042592 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120843923|UniProtKB=A0ACM8EWW4 A0ACM8EWW4 LOC120843923 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8043499|UniProtKB=A0ACM8FQU9 A0ACM8FQU9 Fs(2)Ket PTHR10527:SF1 IMPORTIN BETA IMPORTIN SUBUNIT BETA-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC120838810|UniProtKB=A0ACM8ELC4 A0ACM8ELC4 LOC120838810 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;A2-type glycerophospholipase activity#GO:0004623;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC121834565|UniProtKB=A0ACM8FQN7 A0ACM8FQN7 PTHR47055:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT DERIVED 2 nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 IXOSC|EnsemblGenome=LOC8025429|UniProtKB=A0ACM8G577 A0ACM8G577 scalloped PTHR11834:SF0 TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED PROTEIN SCALLOPED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;embryonic organ development#GO:0048568;animal gross anatomical part developmental process#GO:0160108;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8036091|UniProtKB=A0ACM8FDC7 A0ACM8FDC7 LOC8036091 PTHR17550:SF4 E3 UBIQUITIN-PROTEIN LIGASE TTC3 RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8052644|UniProtKB=A0ACM8DNK3 A0ACM8DNK3 PAN2 PTHR15728:SF0 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 PAN2-PAN3 DEADENYLATION COMPLEX CATALYTIC SUBUNIT PAN2 exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;positive regulation of macromolecule metabolic process#GO:0010604;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252 cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC8053635|UniProtKB=A0ACM8DM68 A0ACM8DM68 LOC8053635 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120846344|UniProtKB=A0ACM8F1D3 A0ACM8F1D3 eIF2D PTHR12217:SF4 EUKARYOTIC TRANSLATION INITIATION FACTOR 2D EUKARYOTIC TRANSLATION INITIATION FACTOR 2D translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC115328111|UniProtKB=A0ACM8FSS4 A0ACM8FSS4 LOC115328111 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8026868|UniProtKB=A0ACM8ED58 A0ACM8ED58 PTHR12943:SF27 HOMOCYSTEINE-RESPONSIVE ENDOPLASMIC RETICULUM-RESIDENT UNIQUITIN-LIKE DOMAIN HERPUD PROTEIN FAMILY MEMBER HOMOCYSTEINE-INDUCED ENDOPLASMIC RETICULUM PROTEIN, ISOFORM A signal transduction#GO:0007165;cellular process#GO:0009987;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;biological regulation#GO:0065007;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;response to unfolded protein#GO:0006986;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 IXOSC|EnsemblGenome=LOC8028341|UniProtKB=A0ACM8FYQ5 A0ACM8FYQ5 LOC8028341 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED RH69884P cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC121047837|UniProtKB=A0ACM8FGZ7 A0ACM8FGZ7 LOC121047837 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041600|UniProtKB=A0ACM8EBB7 A0ACM8EBB7 LOC8041600 PTHR12871:SF0 BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;acetylglucosaminyltransferase activity#GO:0008375;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115314371|UniProtKB=A0ACM8DTM8 A0ACM8DTM8 LOC115314371 PTHR24399:SF70 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121836720|UniProtKB=A0ACM8G1B4 A0ACM8G1B4 LOC121836720 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033606|UniProtKB=A0ACM8G786 A0ACM8G786 Ptpmeg PTHR45706:SF4 TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC120836792|UniProtKB=A0ACM8G1B0 A0ACM8G1B0 LOC120836792 PTHR13400:SF4 CHEMOKINE C-C MOTIF RECEPTOR 1 COILED-COIL DOMAIN-CONTAINING PROTEIN 28B-LIKE transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121834583|UniProtKB=A0ACM8E341 A0ACM8E341 LOC8037461 PTHR31826:SF0 NICALIN NICALIN regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120841574|UniProtKB=A0ACM8FRR1 A0ACM8FRR1 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8050556|UniProtKB=A0ACM8FIQ8 A0ACM8FIQ8 LOC8050556 PTHR11610:SF199 LIPASE PANCREATIC TRIACYLGLYCEROL LIPASE-LIKE ISOFORM X2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115323057|UniProtKB=A0ACM8E3K2 A0ACM8E3K2 LOC115323057 PTHR22845:SF5 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 APOPTOTIC PROTEASE-ACTIVATING FACTOR 1 FAS signaling pathway#P00020>Apaf1#P00597;Apoptosis signaling pathway#P00006>Apaf-1#P00301;Huntington disease#P00029>Apaf-1#P00768;p53 pathway#P00059>Apaf#G04703 IXOSC|EnsemblGenome=LOC8029939|UniProtKB=A0ACM8DJ36 A0ACM8DJ36 LOC8029939 PTHR10969:SF33 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED GAMMA-AMINOBUTYRIC ACID RECEPTOR-ASSOCIATED PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;signaling receptor binding#GO:0005102;lipid binding#GO:0008289;protein binding#GO:0005515;phospholipid binding#GO:0005543;GABA receptor binding#GO:0050811;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625 cellular component disassembly#GO:0022411;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein-containing complex disassembly#GO:0032984;response to starvation#GO:0042594;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;cellular response to nutrient levels#GO:0031669;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;response to stress#GO:0006950;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;autophagosome#GO:0005776;organelle membrane#GO:0031090;autophagosome membrane#GO:0000421;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC115331993|UniProtKB=A0ACM8ECQ5 A0ACM8ECQ5 LOC115331993 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8041879|UniProtKB=A0ACM8DSG9 A0ACM8DSG9 LOC8041879 PTHR12001:SF44 GERANYLGERANYL PYROPHOSPHATE SYNTHASE GERANYLGERANYL PYROPHOSPHATE SYNTHASE prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;isoprenoid metabolic process#GO:0006720;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 IXOSC|EnsemblGenome=LOC8044134|UniProtKB=A0ACM8DL86 A0ACM8DL86 LOC8044134 PTHR11001:SF2 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 MITOCHONDRIAL FISSION PROCESS PROTEIN 1 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8034164|UniProtKB=A0ACM8DR53 A0ACM8DR53 Rab30 PTHR47977:SF64 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-30 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 organelle#GO:0043226;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120839200|UniProtKB=A0ACM8EMK9 A0ACM8EMK9 Tbc1d8-9 PTHR47666:SF6 PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC TBC1 DOMAIN FAMILY MEMBER 9 IXOSC|EnsemblGenome=LOC120843562|UniProtKB=A0ACM8EWE7 A0ACM8EWE7 LOC120843562 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025520|UniProtKB=A0ACM8EPU2 A0ACM8EPU2 LOC8025520 PTHR43757:SF2 AMINOMETHYLTRANSFERASE AMINOMETHYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8035265|UniProtKB=A0ACM8G6B4 A0ACM8G6B4 SNF4Agamma PTHR13780:SF166 AMP-ACTIVATED PROTEIN KINASE, GAMMA REGULATORY SUBUNIT LD22662P anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;nucleotide binding#GO:0000166;molecular function regulator activity#GO:0098772;binding#GO:0005488;kinase binding#GO:0019900;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207 regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;cellular response to nutrient levels#GO:0031669;regulation of carbohydrate metabolic process#GO:0006109;cellular response to starvation#GO:0009267;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;cellular response to glucose starvation#GO:0042149;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;response to nutrient levels#GO:0031667;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;cellular response to stress#GO:0033554;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to starvation#GO:0042594 transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC8035278|UniProtKB=A0ACM8F9X9 A0ACM8F9X9 LOC8035278 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8053991|UniProtKB=A0ACM8DN02 A0ACM8DN02 LOC8053991 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;bicarbonate transmembrane transporter activity#GO:0015106;monoatomic ion transmembrane transporter activity#GO:0015075;dicarboxylic acid transmembrane transporter activity#GO:0005310 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120842397|UniProtKB=A0ACM8EUS5 A0ACM8EUS5 LOC120842397 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8029918|UniProtKB=A0ACM8E140 A0ACM8E140 LOC8029918 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115316323|UniProtKB=A0ACM8FWY5 A0ACM8FWY5 LOC115316323 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120839409|UniProtKB=A0ACM8FRY1 A0ACM8FRY1 LOC120839409 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121837043|UniProtKB=A0ACM8G1N7 A0ACM8G1N7 LOC121837043 PTHR23430:SF7 HISTONE H2A HISTONE H2A.V structural molecule activity#GO:0005198 negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120848320|UniProtKB=A0ACM8F5L4 A0ACM8F5L4 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332800|UniProtKB=A0ACM8EX78 A0ACM8EX78 LOC115332800 PTHR36694:SF14 PASIFLORA 1, ISOFORM A-RELATED LP21121P IXOSC|EnsemblGenome=LOC8037567|UniProtKB=A0ACM8F0N5 A0ACM8F0N5 LOC8037567 PTHR11040:SF223 ZINC/IRON TRANSPORTER ZRT (ZRT), IRT- (IRT-) LIKE PROTEIN TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8039073|UniProtKB=A0ACM8F4I4 A0ACM8F4I4 LOC8039073 PTHR16024:SF4 XK-RELATED PROTEIN XK-RELATED PROTEIN cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277;import into cell#GO:0098657;membrane invagination#GO:0010324;endomembrane system organization#GO:0010256;cellular process#GO:0009987;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;lipid localization#GO:0010876;endocytosis#GO:0006897;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;phagocytosis#GO:0006909;biological regulation#GO:0065007;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;lipid transport#GO:0006869;macromolecule localization#GO:0033036;localization#GO:0051179;anatomical structure development#GO:0048856;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;cell death#GO:0008219;programmed cell death#GO:0012501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115330987|UniProtKB=A0ACM8EBZ6 A0ACM8EBZ6 PTHR21610:SF9 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120844926|UniProtKB=A0ACM8EZK4 A0ACM8EZK4 LOC120844926 PTHR11686:SF77 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121836463|UniProtKB=A0ACM8FYS1 A0ACM8FYS1 LOC121836463 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315185|UniProtKB=A0ACM8EZV3 A0ACM8EZV3 LOC115315185 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8053153|UniProtKB=A0ACM8FYF0 A0ACM8FYF0 LOC8053153 PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8036735|UniProtKB=A0ACM8EA25 A0ACM8EA25 ATPsynC PTHR10031:SF0 ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL ATPASE PROTEIN 9 ATP synthase#PC00002;primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC115309325|UniProtKB=A0ACM8E9Y1 A0ACM8E9Y1 LOC115309325 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316382|UniProtKB=A0ACM8G2X4 A0ACM8G2X4 LOC115316382 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115308173|UniProtKB=A0ACM8F471 A0ACM8F471 LOC115308173 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835348|UniProtKB=A0ACM8FUN4 A0ACM8FUN4 LOC121835348 PTHR28652:SF2 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2 IXOSC|EnsemblGenome=LOC8029827|UniProtKB=A0ACM8G601 A0ACM8G601 LOC8029827 PTHR10066:SF70 BETA-GLUCURONIDASE BETA-GLUCURONIDASE carbohydrate binding#GO:0030246;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;binding#GO:0005488;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC120836800|UniProtKB=A0ACM8FR99 A0ACM8FR99 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030231|UniProtKB=A0ACM8DT06 A0ACM8DT06 LOC8030231 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835383|UniProtKB=A0ACM8FUF1 A0ACM8FUF1 LOC121835383 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023345|UniProtKB=A0ACM8DGV8 A0ACM8DGV8 Vps29 PTHR11124:SF12 VACUOLAR SORTING PROTEIN VPS29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 29 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle#GO:0031982;retromer complex#GO:0030904;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC8034250|UniProtKB=A0ACM8ECE2 A0ACM8ECE2 PTHR11009:SF1 DER1-LIKE PROTEIN, DERLIN DERLIN-1 signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;response to unfolded protein#GO:0006986;cellular response to topologically incorrect protein#GO:0035967;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8041237|UniProtKB=A0ACM8EV22 A0ACM8EV22 Uch PTHR10589:SF17 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC115308386|UniProtKB=A0ACM8FI37 A0ACM8FI37 LOC115308386 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 sodium ion transport#GO:0006814;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8042590|UniProtKB=A0ACM8FGU1 A0ACM8FGU1 LOC8042590 PTHR21964:SF34 BREAST CANCER METASTASIS-SUPPRESSOR 1 SIN3 HISTONE DEACETYLASE COREPRESSOR COMPLEX COMPONENT SDS3 binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;histone deacetylase binding#GO:0042826 negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC121837716|UniProtKB=A0ACM8G5V7 A0ACM8G5V7 LOC121837716 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053513|UniProtKB=A0ACM8F6K5 A0ACM8F6K5 LOC8053513 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8052399|UniProtKB=A0ACM8DNB5 A0ACM8DNB5 LOC8052399 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC120846859|UniProtKB=A0ACM8F2K3 A0ACM8F2K3 TfIIFbeta PTHR10445:SF0 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIFbeta#P00667;Transcription regulation by bZIP transcription factor#P00055>TFIIFbeta#P01396 IXOSC|EnsemblGenome=LOC8051969|UniProtKB=A0ACM8EF09 A0ACM8EF09 LOC8051969 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 binding#GO:0005488;steroid hydroxylase activity#GO:0008395;tetrapyrrole binding#GO:0046906;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629;response to stimulus#GO:0050896;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120848128|UniProtKB=A0ACM8F5H8 A0ACM8F5H8 LOC120848128 PTHR11080:SF2 PYRAZINAMIDASE/NICOTINAMIDASE NICOTINAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8051451|UniProtKB=A0ACM8DNY7 A0ACM8DNY7 LOC8051451 PTHR43330:SF28 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1D, MITOCHONDRIAL metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121836509|UniProtKB=A0ACM8FYX9 A0ACM8FYX9 LOC121836509 PTHR37162:SF10 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037350|UniProtKB=A0ACM8FQT4 A0ACM8FQT4 PTHR10156:SF0 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE 2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;cyclic-nucleotide phosphodiesterase activity#GO:0004112 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC8051438|UniProtKB=A0ACM8FCW2 A0ACM8FCW2 LOC8051438 PTHR11351:SF104 ACYL-COA DESATURASE DESATURASE 1, ISOFORM A-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;unsaturated fatty acid biosynthetic process#GO:0006636;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120843337|UniProtKB=A0ACM8EVU8 A0ACM8EVU8 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121836575|UniProtKB=A0ACM8FZ67 A0ACM8FZ67 LOC121836575 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121833912|UniProtKB=A0ACM8FNQ9 A0ACM8FNQ9 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837729|UniProtKB=A0ACM8G4X0 A0ACM8G4X0 LOC121837729 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC115322574|UniProtKB=A0ACM8E3F6 A0ACM8E3F6 LOC115322574 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8026994|UniProtKB=A0ACM8DMU3 A0ACM8DMU3 LOC8026994 PTHR10073:SF47 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL DNA MISMATCH REPAIR PROTEIN MLH3 double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;mismatch repair#GO:0006298;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115323366|UniProtKB=A0ACM8F4Q7 A0ACM8F4Q7 LOC115323366 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121047558|UniProtKB=A0ACM8G077 A0ACM8G077 LOC121047558 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115316322|UniProtKB=A0ACM8EZA8 A0ACM8EZA8 LOC115316322 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121835476|UniProtKB=A0ACM8FTH7 A0ACM8FTH7 LOC121835476 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 IXOSC|EnsemblGenome=LOC8031219|UniProtKB=A0ACM8DUK5 A0ACM8DUK5 Arf102F PTHR11711:SF481 ADP RIBOSYLATION FACTOR-RELATED ADP RIBOSYLATION FACTOR 4 guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 IXOSC|EnsemblGenome=LOC120846238|UniProtKB=A0ACM8F141 A0ACM8F141 LOC120846238 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120846891|UniProtKB=A0ACM8F4C9 A0ACM8F4C9 LOC120846891 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309139|UniProtKB=A0ACM8F1E9 A0ACM8F1E9 LOC115309139 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120836937|UniProtKB=A0ACM8G328 A0ACM8G328 LOC120836937 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8044056|UniProtKB=A0ACM8DN45 A0ACM8DN45 LOC8044056 PTHR43149:SF7 ENOYL-COA HYDRATASE DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE, MITOCHONDRIAL isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity#GO:0003824 lipid modification#GO:0030258;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 hydratase#PC00120 IXOSC|EnsemblGenome=LOC121837301|UniProtKB=A0ACM8G2R6 A0ACM8G2R6 LOC121837301 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC115327374|UniProtKB=A0ACM8E712 A0ACM8E712 LOC115327374 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8035112|UniProtKB=A0ACM8DJQ4 A0ACM8DJQ4 Chpf PTHR12369:SF13 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;structural molecule activity#GO:0005198;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;protein complex scaffold activity#GO:0140378 primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115332709|UniProtKB=A0ACM8EE07 A0ACM8EE07 Atg9 PTHR13038:SF10 APG9 AUTOPHAGY 9 AUTOPHAGY-RELATED PROTEIN 9 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;intramembrane lipid carrier activity#GO:0140303 autophagosome assembly#GO:0000045;intracellular protein localization#GO:0008104;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;reticulophagy#GO:0061709;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;localization#GO:0051179;organelle assembly#GO:0070925;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;cellular component organization#GO:0016043 autophagosome#GO:0005776;intracellular organelle#GO:0043229;phagophore assembly site#GO:0000407;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 IXOSC|EnsemblGenome=LOC8023133|UniProtKB=A0ACM8DGF5 A0ACM8DGF5 LOC8023133 PTHR10169:SF38 DNA TOPOISOMERASE/GYRASE DNA TOPOISOMERASE 2 catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 resolution of meiotic recombination intermediates#GO:0000712;cellular process#GO:0009987;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;sister chromatid segregation#GO:0000819;primary metabolic process#GO:0044238;meiosis I#GO:0007127;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;meiotic cell cycle process#GO:1903046;homologous recombination#GO:0035825;reproductive process#GO:0022414;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;organelle fission#GO:0048285 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 DNA replication#P00017>Top#P00530;DNA replication#P00017>DNA Topisomerase#P00536 IXOSC|EnsemblGenome=LOC115329401|UniProtKB=A0ACM8E9J1 A0ACM8E9J1 LOC115329401 PTHR13627:SF31 FUKUTIN RELATED PROTEIN RIBITOL 5-PHOSPHATE TRANSFERASE FKRP phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;metabolic process#GO:0008152 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120851162|UniProtKB=A0ACM8FAV8 A0ACM8FAV8 LOC120851162 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115322652|UniProtKB=A0ACM8G7E4 A0ACM8G7E4 Hs6st PTHR12812:SF0 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 transferase#PC00220 IXOSC|EnsemblGenome=LOC115315720|UniProtKB=A0ACM8ERA6 A0ACM8ERA6 LOC115315720 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838187|UniProtKB=A0ACM8EK96 A0ACM8EK96 LOC120838187 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310828|UniProtKB=A0ACM8DQ47 A0ACM8DQ47 LOC115310828 PTHR46811:SF1 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 7 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8026094|UniProtKB=A0ACM8G5G3 A0ACM8G5G3 LOC8026094 PTHR23200:SF48 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 METALLO-BETA-LACTAMASE DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8024709|UniProtKB=A0ACM8ED13 A0ACM8ED13 LOC8024709 PTHR10057:SF23 PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR TRANSLOCATOR PROTEIN cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 IXOSC|EnsemblGenome=LOC115320683|UniProtKB=A0ACM8EVN0 A0ACM8EVN0 LOC115320683 PTHR46599:SF9 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED 4-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8026640|UniProtKB=A0ACM8EPX1 A0ACM8EPX1 LOC8026640 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8052920|UniProtKB=A0ACM8FPL3 A0ACM8FPL3 PTHR10896:SF74 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE P transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;protein metabolic process#GO:0019538 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115329075|UniProtKB=A0ACM8E913 A0ACM8E913 LOC115329075 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115333123|UniProtKB=A0ACM8FSM4 A0ACM8FSM4 LOC115333123 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8040151|UniProtKB=A0ACM8G129 A0ACM8G129 LOC8040151 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115313099|UniProtKB=A0ACM8F645 A0ACM8F645 LOC115313099 PTHR43108:SF8 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER SD21168P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120850029|UniProtKB=A0ACM8F915 A0ACM8F915 LOC120850029 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027350|UniProtKB=A0ACM8FK34 A0ACM8FK34 LOC8027350 PTHR10429:SF0 DNA-3-METHYLADENINE GLYCOSYLASE DNA-3-METHYLADENINE GLYCOSYLASE DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 IXOSC|EnsemblGenome=LOC8052521|UniProtKB=A0ACM8EMD9 A0ACM8EMD9 LOC8052521 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120850876|UniProtKB=A0ACM8FB43 A0ACM8FB43 LOC120850876 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041959|UniProtKB=A0ACM8EWK9 A0ACM8EWK9 LOC8041959 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8035892|UniProtKB=A0ACM8EK21 A0ACM8EK21 LOC8035892 PTHR24317:SF7 PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 diterpenoid metabolic process#GO:0016101;isoprenoid metabolic process#GO:0006720;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043697|UniProtKB=A0ACM8E747 A0ACM8E747 LOC8043697 PTHR12301:SF8 SAM-DOMAIN, SH3 AND NUCLEAR LOCALIZATION SIGNALS PROTEIN RELATED STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 5 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 IXOSC|EnsemblGenome=LOC121836030|UniProtKB=A0ACM8FWW2 A0ACM8FWW2 LOC121836030 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8030900|UniProtKB=A0ACM8DHP3 A0ACM8DHP3 LOC8030900 PTHR12322:SF129 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT PROTEIN DOUBLESEX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;sex differentiation#GO:0007548;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process involved in reproduction#GO:0003006;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8023773|UniProtKB=A0ACM8DPQ3 A0ACM8DPQ3 LOC8023773 PTHR45996:SF3 AGAP001464-PB CREB-H TRANSCRIPTION FACTOR HOMOLOG LET-607 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 IXOSC|EnsemblGenome=LOC115310514|UniProtKB=A0ACM8FRD1 A0ACM8FRD1 PTHR47972:SF45 KINESIN-LIKE PROTEIN KLP-3 PROTEIN CLARET SEGREGATIONAL microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC120842514|UniProtKB=A0ACM8ETT1 A0ACM8ETT1 LOC120842514 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8031760|UniProtKB=A0ACM8DIN6 A0ACM8DIN6 LOC8031760 PTHR10996:SF277 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8035083|UniProtKB=A0ACM8E8V5 A0ACM8E8V5 LOC8035083 PTHR31022:SF7 CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN CENTRIOLE, CILIA AND SPINDLE-ASSOCIATED PROTEIN-LIKE protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of spindle organization#GO:0090224;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of microtubule-based process#GO:0032886;regulation of mitotic spindle organization#GO:0060236;regulation of spindle assembly#GO:0090169;regulation of organelle assembly#GO:1902115;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of mitotic spindle assembly#GO:1901673 intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ciliary transition zone#GO:0035869;intracellular organelle#GO:0043229;cilium#GO:0005929 IXOSC|EnsemblGenome=LOC8042736|UniProtKB=A0ACM8E0R0 A0ACM8E0R0 RpL19 PTHR10722:SF0 60S RIBOSOMAL PROTEIN L19 LARGE RIBOSOMAL SUBUNIT PROTEIN EL19 structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115330732|UniProtKB=A0ACM8EBE7 A0ACM8EBE7 LOC115330732 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC120843731|UniProtKB=A0ACM8EWJ7 A0ACM8EWJ7 LOC120843731 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847678|UniProtKB=A0ACM8F3M5 A0ACM8F3M5 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8053483|UniProtKB=A0ACM8FA14 A0ACM8FA14 l(3)73Ah PTHR45893:SF3 POLYCOMB GROUP RING FINGER PROTEIN POLYCOMB GROUP RING FINGER PROTEIN 3 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC121048390|UniProtKB=A0ACM8FJ89 A0ACM8FJ89 LOC121048390 PTHR13817:SF175 TITIN NEUROGLIAN structural protein#PC00211 IXOSC|EnsemblGenome=LOC8051022|UniProtKB=A0ACM8DLF3 A0ACM8DLF3 LOC8051022 PTHR15692:SF20 MASTERMIND-LIKE MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15-LIKE gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC120836874|UniProtKB=A0ACM8EFL4 A0ACM8EFL4 LOC120836874 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8032420|UniProtKB=A0ACM8EFG2 A0ACM8EFG2 LOC8032420 PTHR15960:SF5 LD44032P LD44032P protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle membrane#GO:0012506;membrane#GO:0016020;ESCRT I complex#GO:0000813;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC115326392|UniProtKB=A0ACM8E6V0 A0ACM8E6V0 ScsbetaG PTHR11815:SF18 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [GDP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;tricarboxylic acid cycle#GO:0006099;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 ligase#PC00142 IXOSC|EnsemblGenome=LOC120846583|UniProtKB=A0ACM8FG20 A0ACM8FG20 LOC120846583 PTHR46331:SF2 VALACYCLOVIR HYDROLASE SERINE HYDROLASE BPHL hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8038431|UniProtKB=A0ACM8FHY3 A0ACM8FHY3 LOC8038431 PTHR47165:SF13 OS03G0429900 PROTEIN REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT IXOSC|EnsemblGenome=LOC120844708|UniProtKB=A0ACM8EZJ4 A0ACM8EZJ4 LOC120844708 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120844595|UniProtKB=A0ACM8F049 A0ACM8F049 LOC120844595 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121047826|UniProtKB=A0ACM8FHW2 A0ACM8FHW2 LOC121047826 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115323432|UniProtKB=A0ACM8F5M7 A0ACM8F5M7 LOC115323432 PTHR10663:SF376 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN ruffle#GO:0001726;cell projection membrane#GO:0031253;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8052986|UniProtKB=A0ACM8E6K4 A0ACM8E6K4 LOC8052986 PTHR12998:SF0 TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG TRNA:M(4)X MODIFICATION ENZYME TRM13 HOMOLOG nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 IXOSC|EnsemblGenome=LOC120843935|UniProtKB=A0ACM8EXP5 A0ACM8EXP5 LOC120843935 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115328576|UniProtKB=A0ACM8FQE3 A0ACM8FQE3 LOC115328576 PTHR12591:SF0 GLUCOSE-6-PHOSPHATASE FI19814P1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8031744|UniProtKB=A0ACM8E1U5 A0ACM8E1U5 LOC8031744 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC115323039|UniProtKB=A0ACM8F6V4 A0ACM8F6V4 LOC115323039 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8030668|UniProtKB=A0ACM8FS75 A0ACM8FS75 LOC8030668 PTHR22937:SF232 E3 UBIQUITIN-PROTEIN LIGASE RNF165 RING-TYPE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8039240|UniProtKB=A0ACM8G0B9 A0ACM8G0B9 LOC8039240 PTHR23043:SF36 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA PROTEIN SINGLE-MINDED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC120838166|UniProtKB=A0ACM8EJA5 A0ACM8EJA5 LOC120838166 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317103|UniProtKB=A0ACM8EVW4 A0ACM8EVW4 mRpL42 PTHR13450:SF4 MITOCHONDRIAL 39S RIBOSOMAL PROTEIN L42 LARGE RIBOSOMAL SUBUNIT PROTEIN ML42 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120842861|UniProtKB=A0ACM8FNS5 A0ACM8FNS5 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8024127|UniProtKB=A0ACM8DHZ2 A0ACM8DHZ2 LOC8024127 PTHR24280:SF4 CYTOCHROME P450 20A1 CYTOCHROME P450 20A1 oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120848651|UniProtKB=A0ACM8F6G5 A0ACM8F6G5 LOC120848651 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8040448|UniProtKB=A0ACM8EP91 A0ACM8EP91 LOC8040448 PTHR10476:SF17 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1A macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;late endosome to vacuole transport#GO:0045324;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8036834|UniProtKB=A0ACM8DZH0 A0ACM8DZH0 LOC8036834 PTHR10127:SF905 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121833534|UniProtKB=A0ACM8FKA4 A0ACM8FKA4 LOC121833534 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120851157|UniProtKB=A0ACM8FC91 A0ACM8FC91 LOC120851157 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8051130|UniProtKB=A0ACM8EBN2 A0ACM8EBN2 heph PTHR15592:SF14 MATRIN 3/NUCLEAR PROTEIN 220-RELATED HEPHAESTUS, ISOFORM Y RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120838441|UniProtKB=A0ACM8EK01 A0ACM8EK01 LOC120838441 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120850602|UniProtKB=A0ACM8FA92 A0ACM8FA92 LOC120850602 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328696|UniProtKB=A0ACM8EZL6 A0ACM8EZL6 LOC115328696 PTHR20963:SF56 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8034069|UniProtKB=A0ACM8EJ11 A0ACM8EJ11 LOC8034069 PTHR19854:SF15 TRANSDUCIN BETA-LIKE 3 TRANSDUCIN BETA-LIKE PROTEIN 3 binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723 ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027372|UniProtKB=A0ACM8DJ05 A0ACM8DJ05 LOC8027372 PTHR22872:SF11 BTK-BINDING PROTEIN-RELATED BTB DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;transmembrane transport#GO:0055085 IXOSC|EnsemblGenome=LOC8028373|UniProtKB=A0ACM8EKB5 A0ACM8EKB5 LOC8028373 PTHR13769:SF7 APOLIPOPROTEIN B APOLIPOPROTEIN B-100-LIKE transfer/carrier protein#PC00219;apolipoprotein#PC00052 IXOSC|EnsemblGenome=LOC115331575|UniProtKB=A0ACM8G7W8 A0ACM8G7W8 LOC115331575 PTHR24399:SF70 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121834512|UniProtKB=A0ACM8FR55 A0ACM8FR55 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120840261|UniProtKB=A0ACM8EPK7 A0ACM8EPK7 LOC120840261 PTHR14205:SF15 WD-REPEAT PROTEIN EARP AND GARP COMPLEX-INTERACTING PROTEIN 1 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 IXOSC|EnsemblGenome=LOC120847646|UniProtKB=A0ACM8F3L1 A0ACM8F3L1 LOC120847646 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024877|UniProtKB=A0ACM8DIS1 A0ACM8DIS1 LOC8024877 PTHR28603:SF1 TRANSMEMBRANE PROTEIN 243 TRANSMEMBRANE PROTEIN 243 IXOSC|EnsemblGenome=LOC115316451|UniProtKB=A0ACM8EZE8 A0ACM8EZE8 LOC121837413 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115330270|UniProtKB=A0ACM8EXP6 A0ACM8EXP6 LOC115330270 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8051513|UniProtKB=A0ACM8E092 A0ACM8E092 PTHR43048:SF3 METHYLMALONYL-COA EPIMERASE METHYLMALONYL-COA EPIMERASE, MITOCHONDRIAL isomerase activity#GO:0016853;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 epimerase/racemase#PC00096;isomerase#PC00135 Methylmalonyl pathway#P02755>Methylmalonyl-CoA epimerase#P03032 IXOSC|EnsemblGenome=LOC8035483|UniProtKB=A0ACM8EE35 A0ACM8EE35 LOC8035483 PTHR10937:SF0 GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING GLUTAMINE--FRUCTOSE-6-PHOSPHATE TRANSAMINASE (ISOMERIZING) transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-sugar metabolic process#GO:0009225;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;amino sugar metabolic process#GO:0006040;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;UDP-N-acetylglucosamine metabolic process#GO:0006047;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine biosynthetic process#GO:0006048 transaminase#PC00216 O-antigen biosynthesis#P02757>Fructose-6-phosphate aminotransferase#P03051;N-acetylglucosamine metabolism#P02756>Fructose-6-phosphate aminotransferase#P03042 IXOSC|EnsemblGenome=LOC8037163|UniProtKB=A0ACM8DN19 A0ACM8DN19 Tmem131 PTHR22050:SF3 RW1 PROTEIN HOMOLOG TRANSMEMBRANE PROTEIN 131 HOMOLOG metabolic process#GO:0008152;cellular process#GO:0009987;biosynthetic process#GO:0009058 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8051054|UniProtKB=A0ACM8E5C9 A0ACM8E5C9 LOC8051054 PTHR22958:SF43 GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE PHOSPHODIESTERASE GPCPD1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629;organophosphate catabolic process#GO:0046434;glycerophospholipid catabolic process#GO:0046475;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC8030861|UniProtKB=A0ACM8DPR9 A0ACM8DPR9 ALiX PTHR23030:SF39 PCD6 INTERACTING PROTEIN-RELATED PROGRAMMED CELL DEATH 6-INTERACTING PROTEIN intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;protein localization to vacuole#GO:0072665;localization#GO:0051179;protein metabolic process#GO:0019538;cell cycle#GO:0007049;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cell division#GO:0051301;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;mitotic cytokinesis#GO:0000281;protein localization to organelle#GO:0033365;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytokinesis#GO:0000910;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;cytoskeleton-dependent cytokinesis#GO:0061640;cellular localization#GO:0051641;protein transport#GO:0015031;cell cycle process#GO:0022402;establishment of protein localization to vacuole#GO:0072666;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8028356|UniProtKB=A0ACM8DJM7 A0ACM8DJM7 LOC8028356 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120841672|UniProtKB=A0ACM8G860 A0ACM8G860 LOC120841672 PTHR10457:SF7 MEVALONATE KINASE/GALACTOKINASE GALACTOKINASE-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065;kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 Fructose galactose metabolism#P02744>Galactokinase#P02960 IXOSC|EnsemblGenome=LOC8053508|UniProtKB=A0ACM8FBY8 A0ACM8FBY8 LOC8053508 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=ISCI007420|UniProtKB=B7PS00 B7PS00 IscW_ISCW007420 PTHR44129:SF18 WD REPEAT-CONTAINING PROTEIN POP1 LISSENCEPHALY-1 HOMOLOG microtubule-based movement#GO:0007018;centrosome localization#GO:0051642;organelle localization#GO:0051640;axonal transport#GO:0098930;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;localization#GO:0051179;axo-dendritic transport#GO:0008088;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630 IXOSC|EnsemblGenome=LOC121835243|UniProtKB=A0ACM8FTH9 A0ACM8FTH9 LOC121835243 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037528|UniProtKB=A0ACM8G2J1 A0ACM8G2J1 Arp8 PTHR11937:SF13 ACTIN ACTIN-RELATED PROTEIN 8 mRNA binding#GO:0003729;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleic acid binding#GO:0003676;structural molecule activity#GO:0005198;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;double-strand break repair#GO:0006302;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Ino80 complex#GO:0031011;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603 actin and actin related protein#PC00039 IXOSC|EnsemblGenome=LOC8031664|UniProtKB=A0ACM8EFX3 A0ACM8EFX3 LOC8031664 PTHR11733:SF224 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120844513|UniProtKB=A0ACM8EZY6 A0ACM8EZY6 LOC120844513 PTHR11439:SF463 GAG-POL-RELATED RETROTRANSPOSON INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115320357|UniProtKB=A0ACM8F2I7 A0ACM8F2I7 LOC115320357 PTHR18839:SF0 MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 MISP FAMILY MEMBER MITOTIC INTERACTOR AND SUBSTRATE OF PLK1 ISOFORM X1 IXOSC|EnsemblGenome=LOC120841139|UniProtKB=A0ACM8EQU0 A0ACM8EQU0 LOC120841139 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318062|UniProtKB=A0ACM8DY43 A0ACM8DY43 AMPKalpha PTHR24343:SF576 SERINE/THREONINE KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 negative regulation of TORC1 signaling#GO:1904262;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;positive regulation of catabolic process#GO:0009896;intracellular protein localization#GO:0008104;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;macromolecule localization#GO:0033036;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;cellular response to glucose starvation#GO:0042149;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;localization#GO:0051179;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;negative regulation of TOR signaling#GO:0032007;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8052096|UniProtKB=A0ACM8ERM1 A0ACM8ERM1 LOC8052096 PTHR45718:SF4 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Hedgehog signaling pathway#P00025>Cubitus interruptus#P00690;Hedgehog signaling pathway#P00025>Cubitus interruptus repressor#P00687 IXOSC|EnsemblGenome=LOC115332324|UniProtKB=A0ACM8EDL7 A0ACM8EDL7 LOC115332324 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324666|UniProtKB=A0ACM8E428 A0ACM8E428 LOC115324666 PTHR21622:SF0 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 4 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;protein maturation#GO:0051604;mitochondrial protein import pathway#GO:7770058;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;cellular localization#GO:0051641;localization#GO:0051179;primary metabolic process#GO:0044238;mitochondrial transport#GO:0006839 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115330845|UniProtKB=A0ACM8ECT3 A0ACM8ECT3 LOC115330845 PTHR11662:SF465 SOLUTE CARRIER FAMILY 17 SIALIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115333153|UniProtKB=A0ACM8EEN7 A0ACM8EEN7 S6kII PTHR24351:SF110 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;TORC1 signaling#GO:0038202;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;TOR signaling#GO:0031929 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Interleukin signaling pathway#P00036>p90RSK#P00964;PDGF signaling pathway#P00047>p90RSK#P01142 IXOSC|EnsemblGenome=LOC115311214|UniProtKB=A0ACM8F1U1 A0ACM8F1U1 LOC115311214 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120850452|UniProtKB=A0ACM8F8S0 A0ACM8F8S0 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;membrane organization#GO:0061024;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule localization#GO:0033036;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;transport#GO:0006810;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;cellular localization#GO:0051641;endomembrane system organization#GO:0010256;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC8023466|UniProtKB=A0ACM8G785 A0ACM8G785 LOC8023466 PTHR10704:SF44 CARBOHYDRATE SULFOTRANSFERASE LD35051P-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 amino sugar metabolic process#GO:0006040;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115330839|UniProtKB=A0ACM8EVQ9 A0ACM8EVQ9 LOC115330839 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC121837724|UniProtKB=A0ACM8G675 A0ACM8G675 LOC121837724 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314000|UniProtKB=A0ACM8EMI3 A0ACM8EMI3 LOC115314000 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115327823|UniProtKB=A0ACM8EG46 A0ACM8EG46 LOC115327823 PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;catabolic process#GO:0009056;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;lysosome#GO:0005764 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC8034756|UniProtKB=A0ACM8E7X2 A0ACM8E7X2 PTHR24300:SF445 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 18A1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395 cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;steroid metabolic process#GO:0008202;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115309465|UniProtKB=A0ACM8DNP2 A0ACM8DNP2 PTHR12047:SF3 FANCONI ANEMIA GROUP A PROTEIN FANCONI ANEMIA A nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8043781|UniProtKB=A0ACM8DGX7 A0ACM8DGX7 LOC8043781 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8032331|UniProtKB=A0ACM8EDX5 A0ACM8EDX5 Jarid2 PTHR10694:SF149 LYSINE-SPECIFIC DEMETHYLASE PROTEIN JUMONJI protein demethylase activity#GO:0140457;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC120843249|UniProtKB=A0ACM8EVH6 A0ACM8EVH6 LOC120843249 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8043144|UniProtKB=A0ACM8DL26 A0ACM8DL26 LOC8043144 PTHR31400:SF1 GUANYLYL CYCLASE DOMAIN CONTAINING PROTEIN 1 GUCD1 PROTEIN GUCD1 guanylate cyclase#PC00114 IXOSC|EnsemblGenome=LOC115316215|UniProtKB=A0ACM8DVQ1 A0ACM8DVQ1 LOC115316215 PTHR31699:SF1 NUDIX T16 FAMILY MEMBER U8 SNORNA-DECAPPING ENZYME binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;snoRNA binding#GO:0030515;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115315704|UniProtKB=A0ACM8DV37 A0ACM8DV37 LOC115315704 PTHR14388:SF17 T CELL-SPECIFIC ADAPTER PROTEIN TSAD SH2 DOMAIN-CONTAINING PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC120840634|UniProtKB=A0ACM8FKW3 A0ACM8FKW3 LOC120840634 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120840748|UniProtKB=A0ACM8EQ09 A0ACM8EQ09 LOC120840748 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311727|UniProtKB=A0ACM8DRC7 A0ACM8DRC7 LOC115311727 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031436|UniProtKB=A0ACM8G2R8 A0ACM8G2R8 LOC8031436 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8026199|UniProtKB=A0ACM8DNE7 A0ACM8DNE7 LOC8026199 PTHR10749:SF7 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA-RELATED cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 IXOSC|EnsemblGenome=LOC8051201|UniProtKB=A0ACM8FM75 A0ACM8FM75 LOC8051201 PTHR46061:SF3 THYROTROPIN-RELEASING HORMONE RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 Thyrotropin-releasing hormone receptor signaling pathway#P04394>TRH Receptor#P04580 IXOSC|EnsemblGenome=LOC8027830|UniProtKB=A0ACM8DU22 A0ACM8DU22 LOC8027830 PTHR13651:SF1 PROTEIN ABITRAM PROTEIN ABITRAM actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin monomer binding#GO:0003785;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of actin cytoskeleton organization#GO:0032956;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular process#GO:0009987;neuron projection development#GO:0031175;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of anatomical structure size#GO:0090066;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;regulation of cellular component size#GO:0032535;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of biological quality#GO:0065008;neuron development#GO:0048666;dendrite development#GO:0016358;regulation of actin filament length#GO:0030832;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin filament polymerization#GO:0030833;multicellular organismal process#GO:0032501;regulation of actin filament organization#GO:0110053;regulation of filopodium assembly#GO:0051489;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;dendrite morphogenesis#GO:0048813;system development#GO:0048731;regulation of cell projection assembly#GO:0060491;anatomical structure development#GO:0048856 nucleus#GO:0005634;neuron projection#GO:0043005;cell leading edge#GO:0031252;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;lamellipodium#GO:0030027;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115316029|UniProtKB=A0ACM8FUA2 A0ACM8FUA2 LOC115316029 PTHR11010:SF128 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8042120|UniProtKB=A0ACM8EBS3 A0ACM8EBS3 twr PTHR10806:SF6 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 SIGNAL PEPTIDASE COMPLEX CATALYTIC SUBUNIT SEC11 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 serine protease#PC00203 Vasopressin synthesis#P04395>Signal Peptidase#P04589;Endothelin signaling pathway#P00019>signal peptidase#P00573 IXOSC|EnsemblGenome=LOC115330419|UniProtKB=A0ACM8EZA5 A0ACM8EZA5 LOC115330419 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8042180|UniProtKB=A0ACM8E3C0 A0ACM8E3C0 aPKC PTHR24351:SF216 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8051145|UniProtKB=A0ACM8DLU8 A0ACM8DLU8 PTHR21705:SF12 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309865|UniProtKB=A0ACM8F9F0 A0ACM8F9F0 LOC115309865 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8051951|UniProtKB=A0ACM8G883 A0ACM8G883 LOC8051951 PTHR11690:SF305 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8030649|UniProtKB=A0ACM8ET91 A0ACM8ET91 LOC8030649 PTHR22933:SF31 FI18007P1-RELATED EXPRESSED PROTEIN IXOSC|EnsemblGenome=LOC8036707|UniProtKB=A0ACM8FSJ0 A0ACM8FSJ0 LOC8036707 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 organelle membrane contact site#GO:0044232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC120844862|UniProtKB=A0ACM8EZE4 A0ACM8EZE4 LOC120844862 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 IXOSC|EnsemblGenome=LOC115323149|UniProtKB=A0ACM8EYI5 A0ACM8EYI5 LOC115323149 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8030734|UniProtKB=A0ACM8DVL3 A0ACM8DVL3 LOC8030734 PTHR45688:SF18 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2-LIKE IXOSC|EnsemblGenome=LOC8025464|UniProtKB=A0ACM8DT80 A0ACM8DT80 LOC8025464 PTHR24376:SF216 ZINC FINGER PROTEIN DRACULIN-LIKE 3 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8025151|UniProtKB=A0ACM8DPE6 A0ACM8DPE6 TRAM PTHR12371:SF11 TRANSLOCATION ASSOCIATED MEMBRANE PROTEIN TRANSLOCATING CHAIN-ASSOCIATED MEMBRANE PROTEIN establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120848441|UniProtKB=A0ACM8F615 A0ACM8F615 LOC120848441 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839144|UniProtKB=A0ACM8EKU0 A0ACM8EKU0 LOC120839144 PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 biosynthetic process#GO:0009058;catabolic process#GO:0009056;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC8029131|UniProtKB=A0ACM8EDE6 A0ACM8EDE6 LOC8029131 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8024895|UniProtKB=A0ACM8DWN2 A0ACM8DWN2 LOC8024895 PTHR24056:SF607 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 17 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121838451|UniProtKB=A0ACM8G926 A0ACM8G926 LOC121838451 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835607|UniProtKB=A0ACM8FV61 A0ACM8FV61 LOC121835607 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115326923|UniProtKB=A0ACM8F2X9 A0ACM8F2X9 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120843021|UniProtKB=A0ACM8FRV2 A0ACM8FRV2 LOC120843021 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8026673|UniProtKB=A0ACM8DY42 A0ACM8DY42 LOC8026673 PTHR10067:SF6 PHOSPHATIDYLSERINE DECARBOXYLASE PHOSPHATIDYLSERINE DECARBOXYLASE PROENZYME, MITOCHONDRIAL carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;lyase activity#GO:0016829 phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;lyase#PC00144;decarboxylase#PC00089 IXOSC|EnsemblGenome=LOC8051514|UniProtKB=A0ACM8FXL3 A0ACM8FXL3 LOC8051514 PTHR16198:SF2 INO80 COMPLEX SUBUNIT D INO80 COMPLEX SUBUNIT D intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8039317|UniProtKB=A0ACM8DKB9 A0ACM8DKB9 PTHR43245:SF23 BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA NAD(P)-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035157|UniProtKB=A0ACM8EEA8 A0ACM8EEA8 LOC8035157 PTHR15952:SF11 EXPORTIN-T/LOS1 EXPORTIN-T tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of localization#GO:0051234;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;organelle envelope#GO:0031967;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8040994|UniProtKB=A0ACM8ENV7 A0ACM8ENV7 LOC8040994 PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;extracellular region#GO:0005576 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8041869|UniProtKB=A0ACM8DS77 A0ACM8DS77 LOC8041869 PTHR10881:SF46 GOLGIN SUBFAMILY A MEMBER-RELATED GOLGIN SUBFAMILY A MEMBER 2 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8035232|UniProtKB=A0ACM8EMS2 A0ACM8EMS2 LOC8035232 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8053455|UniProtKB=A0ACM8EV20 A0ACM8EV20 LOC8053455 PTHR10796:SF194 PATCHED-RELATED PATCHED-RELATED, ISOFORM A membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle membrane#GO:0031090;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8044050|UniProtKB=A0ACM8DN25 A0ACM8DN25 LOC8044050 PTHR43011:SF1 IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY 2 HOMOLOG, MITOCHONDRIAL iron ion binding#GO:0005506;cation binding#GO:0043169;iron-sulfur cluster binding#GO:0051536;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 biosynthetic process#GO:0009058;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8051997|UniProtKB=A0ACM8DLH7 A0ACM8DLH7 LOC8051997 PTHR11601:SF65 CYSTEINE DESULFURYLASE FAMILY MEMBER CYSTEINE DESULFURASE sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 lyase#PC00144;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8023852|UniProtKB=A0ACM8EEJ6 A0ACM8EEJ6 Pak PTHR45832:SF24 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED PROTEIN KINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319449|UniProtKB=A0ACM8EZ01 A0ACM8EZ01 LOC115319449 PTHR24241:SF83 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 150-RELATED transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121835094|UniProtKB=A0ACM8FRG0 A0ACM8FRG0 LOC121835094 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115310606|UniProtKB=A0ACM8FNX6 A0ACM8FNX6 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121047169|UniProtKB=A0ACM8G0S1 A0ACM8G0S1 LOC121047169 PTHR45823:SF1 T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN SAP DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838823|UniProtKB=A0ACM8FTY1 A0ACM8FTY1 LOC120838823 PTHR21522:SF58 PROTON CHANNEL OTOP OTOPETRIN channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;localization#GO:0051179;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115328414|UniProtKB=A0ACM8E9G5 A0ACM8E9G5 LOC115328414 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115328394|UniProtKB=A0ACM8EYT6 A0ACM8EYT6 LOC115328394 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8040085|UniProtKB=A0ACM8DKH4 A0ACM8DKH4 SmF PTHR11021:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F SMALL NUCLEAR RIBONUCLEOPROTEIN F nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120843818|UniProtKB=A0ACM8EX08 A0ACM8EX08 LOC120843818 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045915|UniProtKB=A0ACM8FCF9 A0ACM8FCF9 LOC121045915 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028708|UniProtKB=A0ACM8DH39 A0ACM8DH39 LOC8028708 PTHR45624:SF63 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL ORNITHINE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 mitochondrial transmembrane transport#GO:1990542;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;amino acid transmembrane transport#GO:0003333;L-alpha-amino acid transmembrane transport#GO:1902475;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;intracellular transport#GO:0046907;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;establishment of localization#GO:0051234;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transporter#PC00227 IXOSC|EnsemblGenome=LOC8031937|UniProtKB=A0ACM8DIZ7 A0ACM8DIZ7 LOC8031937 PTHR21014:SF6 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 lipid modification#GO:0030258;dephosphorylation#GO:0016311;phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839 intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;vacuole#GO:0005773;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;phagocytic vesicle#GO:0045335;late endosome#GO:0005770;endomembrane system#GO:0012505 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115315009|UniProtKB=A0ACM8FBK3 A0ACM8FBK3 Ufd4 PTHR45670:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE HECTD1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121833389|UniProtKB=A0ACM8FKT0 A0ACM8FKT0 LOC121833389 PTHR10907:SF47 REGUCALCIN REGUCALCIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of calcium-mediated signaling#GO:0050848;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;esterase#PC00097 IXOSC|EnsemblGenome=LOC8025508|UniProtKB=A0ACM8F0I8 A0ACM8F0I8 LOC8025508 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 IXOSC|EnsemblGenome=LOC8042200|UniProtKB=A0ACM8F7E6 A0ACM8F7E6 LOC8042200 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8027232|UniProtKB=A0ACM8ECN5 A0ACM8ECN5 LOC8027232 PTHR11289:SF0 BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN BRCA2 BREAST CANCER TYPE 2 SUSCEPTIBILITY PROTEIN DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;double-strand break repair#GO:0006302;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 IXOSC|EnsemblGenome=LOC120849847|UniProtKB=A0ACM8F9F4 A0ACM8F9F4 LOC120849847 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115330909|UniProtKB=A0ACM8EI97 A0ACM8EI97 LOC115330909 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115331639|UniProtKB=A0ACM8EQR7 A0ACM8EQR7 dos PTHR45960:SF2 GRB2-ASSOCIATED-BINDING PROTEIN PROTEIN DAUGHTER OF SEVENLESS scaffold/adaptor protein#PC00226 EGF receptor signaling pathway#P00018>Gab#P00563 IXOSC|EnsemblGenome=LOC8040688|UniProtKB=A0ACM8DH10 A0ACM8DH10 CIA30 PTHR13194:SF18 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30 COMPLEX I INTERMEDIATE-ASSOCIATED PROTEIN 30, MITOCHONDRIAL cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8043303|UniProtKB=A0ACM8EYI4 A0ACM8EYI4 LOC8043303 PTHR12174:SF103 SIGNAL PEPTIDE PEPTIDASE INTRAMEMBRANE PROTEASE (IMPAS) FAMILY aspartic protease#PC00053;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121046103|UniProtKB=A0ACM8FD06 A0ACM8FD06 LOC121046103 PTHR45902:SF7 LATROPHILIN RECEPTOR-LIKE PROTEIN A G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120842250|UniProtKB=A0ACM8EUG6 A0ACM8EUG6 LOC120842250 PTHR10742:SF423 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A histone demethylase activity#GO:0032452;protein demethylase activity#GO:0140457;heterocyclic compound binding#GO:1901363;demethylase activity#GO:0032451;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;chromatin binding#GO:0003682 regulation of biological process#GO:0050789;cellular process#GO:0009987;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 oxidase#PC00175 IXOSC|EnsemblGenome=LOC8052440|UniProtKB=A0ACM8DLN4 A0ACM8DLN4 LOC8052440 PTHR12303:SF14 CARNOSINE N-METHYLTRANSFERASE PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE CARNMT1 methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity#GO:0016740;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121048431|UniProtKB=A0ACM8FH30 A0ACM8FH30 LOC121048431 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8050990|UniProtKB=A0ACM8E5V4 A0ACM8E5V4 LOC8050990 PTHR23271:SF1 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 66 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 6 HOMOLOG RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511;binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115326869|UniProtKB=A0ACM8E6G7 A0ACM8E6G7 LOC115326869 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120838564|UniProtKB=A0ACM8EKW3 A0ACM8EKW3 LOC120838564 PTHR12821:SF0 BYSTIN BYSTIN snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 IXOSC|EnsemblGenome=LOC8037300|UniProtKB=A0ACM8FI41 A0ACM8FI41 LOC8037300 PTHR10110:SF86 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 7 monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8035924|UniProtKB=A0ACM8FDF6 A0ACM8FDF6 Asap PTHR45854:SF3 ASAP FAMILY MEMBER ARFGAP WITH SH3 DOMAIN, ANK REPEAT AND PH DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC115322409|UniProtKB=A0ACM8FYJ1 A0ACM8FYJ1 LOC121836146 PTHR12183:SF32 MITOCHONDRIAL UBIQUITIN LIGASE ACTIVATOR OF NFKB 1 MITOCHONDRIAL E3 UBIQUITIN PROTEIN LIGASE 1 biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;regulation of protein stability#GO:0031647;positive regulation of cellular process#GO:0048522;regulation of anatomical structure morphogenesis#GO:0022603;protein stabilization#GO:0050821;positive regulation of developmental process#GO:0051094;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;positive regulation of mitochondrial fission#GO:0090141;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;positive regulation of organelle organization#GO:0010638;regulation of biological quality#GO:0065008;positive regulation of cellular component organization#GO:0051130 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120836319|UniProtKB=A0ACM8FJ56 A0ACM8FJ56 LOC120836319 PTHR21461:SF40 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN BETA-1,4-GALACTOSYLTRANSFERASE GALT-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8026606|UniProtKB=A0ACM8E5Q6 A0ACM8E5Q6 Cand1 PTHR12696:SF5 TIP120 CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein-containing complex assembly#GO:0065003;protein modification by small protein conjugation#GO:0032446;cellular component organization#GO:0016043;protein modification process#GO:0036211;primary metabolic process#GO:0044238;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121835210|UniProtKB=A0ACM8FSW1 A0ACM8FSW1 LOC121835210 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8029055|UniProtKB=A0ACM8EW25 A0ACM8EW25 LOC8029055 PTHR47412:SF1 FI01434P-RELATED FI01434P-RELATED IXOSC|EnsemblGenome=LOC121046223|UniProtKB=A0ACM8FDN3 A0ACM8FDN3 LOC121046223 PTHR21461:SF40 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN BETA-1,4-GALACTOSYLTRANSFERASE GALT-1 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8024513|UniProtKB=A0ACM8DTJ8 A0ACM8DTJ8 cert PTHR19308:SF53 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN CERAMIDE TRANSFER PROTEIN cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;ceramide transport#GO:0035627;lipid transport#GO:0006869;transport#GO:0006810;intracellular transport#GO:0046907;lipid localization#GO:0010876;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 IXOSC|EnsemblGenome=LOC115332413|UniProtKB=A0ACM8EY44 A0ACM8EY44 LOC115332413 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121047419|UniProtKB=A0ACM8FWB9 A0ACM8FWB9 LOC121047419 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121835609|UniProtKB=A0ACM8FUF4 A0ACM8FUF4 LOC121835609 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8037711|UniProtKB=A0ACM8EF91 A0ACM8EF91 LOC8037711 PTHR14873:SF1 OS06G0694100 PROTEIN VWFC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326377|UniProtKB=A0ACM8F3W2 A0ACM8F3W2 FIG4 PTHR45738:SF5 POLYPHOSPHOINOSITIDE PHOSPHATASE POLYPHOSPHOINOSITIDE PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311;lipid modification#GO:0030258;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115316320|UniProtKB=A0ACM8EZ90 A0ACM8EZ90 LOC115316320 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8036387|UniProtKB=A0ACM8DJY8 A0ACM8DJY8 LOC8036387 PTHR24279:SF127 CYTOCHROME P450 CYTOCHROME P450 315A1, MITOCHONDRIAL IXOSC|EnsemblGenome=LOC8036330|UniProtKB=A0ACM8DJY5 A0ACM8DJY5 Lamtor2 PTHR13323:SF4 LATE ENDOSOMAL/LYSOSOMAL MP1 INTERACTING PROTEIN RAGULATOR COMPLEX PROTEIN LAMTOR2 protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of TORC1 signaling#GO:1904263;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;regulation of signaling#GO:0023051 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vacuolar membrane#GO:0005774;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115331386|UniProtKB=A0ACM8EXF5 A0ACM8EXF5 LOC115331386 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115314338|UniProtKB=A0ACM8FVN3 A0ACM8FVN3 LOC115314338 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120849748|UniProtKB=A0ACM8F989 A0ACM8F989 LOC120849748 PTHR45951:SF3 PROTEIN DISPATCHED-RELATED PROTEIN DISPATCHED response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;smoothened signaling pathway#GO:0007224;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115333077|UniProtKB=A0ACM8EEB9 A0ACM8EEB9 LOC115333077 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115326962|UniProtKB=A0ACM8G095 A0ACM8G095 LOC115326962 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8037386|UniProtKB=A0ACM8EQE9 A0ACM8EQE9 LOC8037386 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120850784|UniProtKB=A0ACM8FAX2 A0ACM8FAX2 LOC120850784 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121832876|UniProtKB=A0ACM8FS63 A0ACM8FS63 LOC121832876 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115310878|UniProtKB=A0ACM8DQ42 A0ACM8DQ42 LOC115310878 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 transferase#PC00220 IXOSC|EnsemblGenome=LOC8052602|UniProtKB=A0ACM8DLZ5 A0ACM8DLZ5 LOC8052602 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120836484|UniProtKB=A0ACM8EF77 A0ACM8EF77 LOC120836484 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8027085|UniProtKB=A0ACM8FHG2 A0ACM8FHG2 LOC8027085 PTHR15410:SF2 HIRA-INTERACTING PROTEIN 3 HIRA-INTERACTING PROTEIN 3 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8028479|UniProtKB=A0ACM8DGI5 A0ACM8DGI5 mRpS24 PTHR21244:SF1 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S24 SMALL RIBOSOMAL SUBUNIT PROTEIN US3M ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8037113|UniProtKB=A0ACM8FLM8 A0ACM8FLM8 PTHR24388:SF38 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8043390|UniProtKB=A0ACM8DL42 A0ACM8DL42 LOC8043390 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120850615|UniProtKB=A0ACM8FB84 A0ACM8FB84 LOC120850615 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115316938|UniProtKB=A0ACM8DWK4 A0ACM8DWK4 Psf2 PTHR12772:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 DNA REPLICATION COMPLEX GINS PROTEIN PSF2 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;DNA replication preinitiation complex#GO:0031261;chromosome#GO:0005694;organelle lumen#GO:0043233;GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleoplasm#GO:0005654 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115313081|UniProtKB=A0ACM8EYV6 A0ACM8EYV6 LOC115313081 PTHR23235:SF130 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 367 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8040996|UniProtKB=A0ACM8DZI0 A0ACM8DZI0 LOC8040996 PTHR11953:SF2 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT MTR3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;nuclear mRNA surveillance#GO:0071028;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;snRNA metabolic process#GO:0016073;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA 3'-end processing#GO:0031123;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;snRNA 3'-end processing#GO:0034472;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC8031954|UniProtKB=A0ACM8EF47 A0ACM8EF47 Kua PTHR48177:SF1 TRANSMEMBRANE PROTEIN 189 TRANSMEMBRANE PROTEIN 189 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8033295|UniProtKB=A0ACM8E8A1 A0ACM8E8A1 LOC8033295 PTHR21663:SF0 HYPOTHETICAL HEAT DOMAIN-CONTAINING HEAT REPEAT-CONTAINING PROTEIN 5A IXOSC|EnsemblGenome=LOC115323630|UniProtKB=A0ACM8E350 A0ACM8E350 LOC115323630 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8052764|UniProtKB=A0ACM8EZ05 A0ACM8EZ05 LOC8052764 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 IXOSC|EnsemblGenome=LOC8036928|UniProtKB=A0ACM8E1Y8 A0ACM8E1Y8 LOC8036928 PTHR12751:SF18 PHOSPHATASE AND ACTIN REGULATOR PHACTR PHOSPHATASE AND ACTIN REGULATOR 2 phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC8028394|UniProtKB=A0ACM8FRH3 A0ACM8FRH3 LOC8028394 PTHR34008:SF2 REPETITIVE PROLINE-RICH CELL WALL PROTEIN 1 REPETITIVE PROLINE-RICH CELL WALL PROTEIN 1 IXOSC|EnsemblGenome=LOC8038902|UniProtKB=A0ACM8G3I2 A0ACM8G3I2 LOC8038902 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8036064|UniProtKB=A0ACM8ETJ1 A0ACM8ETJ1 LOC8036064 PTHR21522:SF58 PROTON CHANNEL OTOP OTOPETRIN monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8030246|UniProtKB=A0ACM8DGI6 A0ACM8DGI6 LOC8030246 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115327654|UniProtKB=A0ACM8FZ11 A0ACM8FZ11 LOC115327654 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120850705|UniProtKB=A0ACM8F9G6 A0ACM8F9G6 LOC120850705 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8043756|UniProtKB=A0ACM8F2U9 A0ACM8F2U9 LOC8043756 PTHR13500:SF0 NUCLEOLAR PRERIBOSOMAL-ASSOCIATED PROTEIN 1 NUCLEOLAR PRE-RIBOSOMAL-ASSOCIATED PROTEIN 1 RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121837053|UniProtKB=A0ACM8G1D4 A0ACM8G1D4 LOC121837053 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121834025|UniProtKB=A0ACM8FNY0 A0ACM8FNY0 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120839713|UniProtKB=A0ACM8EMN9 A0ACM8EMN9 LOC120839713 PTHR45913:SF5 EPM2A-INTERACTING PROTEIN 1 HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313049|UniProtKB=A0ACM8DSN4 A0ACM8DSN4 LOC115313049 PTHR14315:SF17 SPOT14 FAMILY MEMBER MIP21584P regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;regulation of lipid biosynthetic process#GO:0046890;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8026040|UniProtKB=A0ACM8DWL4 A0ACM8DWL4 LOC8026040 PTHR13774:SF17 PHENAZINE BIOSYNTHESIS PROTEIN PHENAZINE BIOSYNTHESIS-LIKE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8026598|UniProtKB=A0ACM8E671 A0ACM8E671 LOC8026598 PTHR21494:SF3 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 ASC-1 COMPLEX SUBUNIT P100 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 2 protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 IXOSC|EnsemblGenome=LOC120840286|UniProtKB=A0ACM8FW85 A0ACM8FW85 LOC120840286 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8041005|UniProtKB=A0ACM8DGW2 A0ACM8DGW2 LOC8041005 PTHR24249:SF418 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120846508|UniProtKB=A0ACM8FIA9 A0ACM8FIA9 LOC120846508 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115327533|UniProtKB=A0ACM8EV12 A0ACM8EV12 LOC115327533 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;transmembrane transport#GO:0055085;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816 signaling receptor complex#GO:0043235;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC8026859|UniProtKB=A0ACM8DIG3 A0ACM8DIG3 LOC8026859 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED RH69884P membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8025154|UniProtKB=A0ACM8FKN8 A0ACM8FKN8 LOC8025154 PTHR45723:SF1 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO3 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774 cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115319483|UniProtKB=A0ACM8ESU9 A0ACM8ESU9 LOC115319483 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC115329416|UniProtKB=A0ACM8EAG3 A0ACM8EAG3 LOC115329416 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transporter#PC00227 IXOSC|EnsemblGenome=LOC120838776|UniProtKB=A0ACM8EJX9 A0ACM8EJX9 LOC120838776 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097 reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;homologous recombination#GO:0035825;reproductive process#GO:0022414;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8040980|UniProtKB=A0ACM8FTP7 A0ACM8FTP7 LOC8040980 PTHR18968:SF166 THIAMINE PYROPHOSPHATE ENZYMES 2-HYDROXYACYL-COA LYASE 2 flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;transketolase or transaldolase activity#GO:0016744;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;branched-chain amino acid biosynthetic process#GO:0009082;small molecule biosynthetic process#GO:0044283;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038 catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 Valine biosynthesis#P02785>Acetolactate synthase#P03216;Isoleucine biosynthesis#P02748>Acetolactate synthase#P02997 IXOSC|EnsemblGenome=LOC115315669|UniProtKB=A0ACM8DV57 A0ACM8DV57 LOC115315669 PTHR11893:SF40 INNEXIN INNEXIN SHAKING-B channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161 gap junction#PC00105 IXOSC|EnsemblGenome=LOC8029637|UniProtKB=A0ACM8DIJ2 A0ACM8DIJ2 LOC8029637 PTHR46052:SF1 PHOSDUCIN-LIKE PROTEIN PHOSDUCIN-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120847752|UniProtKB=A0ACM8FQT8 A0ACM8FQT8 LOC120847752 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039573|UniProtKB=A0ACM8DT95 A0ACM8DT95 LOC8039573 PTHR12236:SF79 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 64AA-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8027170|UniProtKB=A0ACM8G5C5 A0ACM8G5C5 LOC8027170 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8030424|UniProtKB=A0ACM8E3J7 A0ACM8E3J7 Bap60 PTHR13844:SF95 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D BRAHMA-ASSOCIATED PROTEIN OF 60 KDA transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 IXOSC|EnsemblGenome=LOC8030036|UniProtKB=A0ACM8EDU6 A0ACM8EDU6 LOC8030036 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC115333145|UniProtKB=A0ACM8G0U3 A0ACM8G0U3 LOC115333145 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC121837739|UniProtKB=A0ACM8G4L1 A0ACM8G4L1 LOC121837739 PTHR47501:SF10 TRANSPOSASE-RELATED DUF659 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8039745|UniProtKB=A0ACM8FB86 A0ACM8FB86 PTHR23359:SF206 NUCLEOTIDE KINASE UMP-CMP KINASE phosphotransferase activity, phosphate group as acceptor#GO:0016776;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate metabolic process#GO:0019693;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside diphosphate metabolic process#GO:0009132 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153;De novo pyrimidine ribonucleotides biosythesis#P02740>Uridylate kinase#P02924 IXOSC|EnsemblGenome=LOC8035291|UniProtKB=A0ACM8DJS7 A0ACM8DJS7 LOC8035291 PTHR41146:SF1 DIURETIC HORMONE CLASS 2 DIURETIC HORMONE CLASS 2 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function activator activity#GO:0140677 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;positive regulation of biological process#GO:0048518;regulation of circadian rhythm#GO:0042752;signal transduction#GO:0007165;cellular process#GO:0009987;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 peptide hormone#PC00179 IXOSC|EnsemblGenome=LOC8025436|UniProtKB=A0ACM8EIY3 A0ACM8EIY3 LOC8025436 PTHR12274:SF3 GRANULIN GRANULIN PRECURSOR cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8025986|UniProtKB=A0ACM8ELD7 A0ACM8ELD7 LOC8025986 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094 metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC121833764|UniProtKB=A0ACM8FMK0 A0ACM8FMK0 LOC121833764 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115329007|UniProtKB=A0ACM8FZM5 A0ACM8FZM5 LOC115329007 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8027125|UniProtKB=A0ACM8E332 A0ACM8E332 LOC8027125 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC120838204|UniProtKB=A0ACM8EJE7 A0ACM8EJE7 LOC120838204 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030513|UniProtKB=A0ACM8DH71 A0ACM8DH71 LOC8030513 PTHR10625:SF14 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 8 histone modifying activity#GO:0140993;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity#GO:0003824 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974 Wnt signaling pathway#P00057>Histone deacetylase#P01472 IXOSC|EnsemblGenome=LOC8035133|UniProtKB=A0ACM8ECW7 A0ACM8ECW7 PTHR10361:SF70 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8024815|UniProtKB=A0ACM8DVU7 A0ACM8DVU7 LOC8024815 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115322742|UniProtKB=A0ACM8E381 A0ACM8E381 LOC115322742 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318929|UniProtKB=A0ACM8DZ06 A0ACM8DZ06 LOC115318929 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC121048523|UniProtKB=A0ACM8FHA7 A0ACM8FHA7 LOC121048523 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043644|UniProtKB=A0ACM8EBB2 A0ACM8EBB2 LOC8043644 PTHR23402:SF1 PROTEASE FAMILY C15 PYROGLUTAMYL-PEPTIDASE I-RELATED RE07960P peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8035933|UniProtKB=A0ACM8EJD1 A0ACM8EJD1 Cdk5 PTHR24056:SF594 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 5 cyclin-dependent protein serine/threonine kinase activity#GO:0004693;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 synaptic vesicle localization#GO:0097479;establishment of vesicle localization#GO:0051650;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;synaptic vesicle transport#GO:0048489;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;establishment of organelle localization#GO:0051656;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;apoptotic process#GO:0006915;neuron apoptotic process#GO:0051402;cellular localization#GO:0051641;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;vesicle localization#GO:0051648;cellular developmental process#GO:0048869;establishment of localization#GO:0051234;neurogenesis#GO:0022008;developmental process#GO:0032502;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;programmed cell death#GO:0012501;cell death#GO:0008219;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;organelle localization#GO:0051640 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Axon guidance mediated by semaphorins#P00007>Cdk5#P00336;Dopamine receptor mediated signaling pathway#P05912>CDK5#P05951;Nicotine pharmacodynamics pathway#P06587>CDK5#P06597;PDGF signaling pathway#P00047>GSK3#P01153;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902 IXOSC|EnsemblGenome=LOC8052361|UniProtKB=A0ACM8G2S8 A0ACM8G2S8 LOC8052361 PTHR24333:SF17 HOMEO BOX HB9 LIKE A-RELATED HOMEOBOX PROTEIN UNPLUGGED-RELATED helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8040096|UniProtKB=A0ACM8G8T8 A0ACM8G8T8 Rbfox1 PTHR15597:SF51 ATAXIN 2-BINDING PROTEIN 1-RELATED RNA-BINDING FOX PROTEIN 1, ISOFORM H RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120846012|UniProtKB=A0ACM8F0K3 A0ACM8F0K3 LOC120846012 PTHR13507:SF0 PRKR-INTERACTING PROTEIN 1 PRKR-INTERACTING PROTEIN 1 enzyme inhibitor activity#GO:0004857;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function inhibitor activity#GO:0140678 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8026937|UniProtKB=A0ACM8EM15 A0ACM8EM15 PTHR22972:SF7 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PINK1, MITOCHONDRIAL phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of anatomical structure morphogenesis#GO:0022603;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;positive regulation of developmental process#GO:0051094;regulation of apoptotic process#GO:0042981;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of mitochondrial fission#GO:0090141;regulation of mitochondrial fission#GO:0090140;regulation of developmental process#GO:0050793;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of mitochondrion organization#GO:0010821;regulation of organelle organization#GO:0033043;positive regulation of organelle organization#GO:0010638;process utilizing autophagic mechanism#GO:0061919;positive regulation of cellular component organization#GO:0051130 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8035393|UniProtKB=A0ACM8EA26 A0ACM8EA26 Ubr3 PTHR21497:SF39 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR3 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115330832|UniProtKB=A0ACM8FAL3 A0ACM8FAL3 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8026474|UniProtKB=A0ACM8DQA3 A0ACM8DQA3 LOC8026474 PTHR21040:SF8 BCDNA.GH04120 HEXOSAMINIDASE D catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8040612|UniProtKB=A0ACM8E3F5 A0ACM8E3F5 LOC8040612 PTHR15741:SF27 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR AP-4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8025528|UniProtKB=A0ACM8FM12 A0ACM8FM12 LOC8025528 PTHR11339:SF416 EXTRACELLULAR MATRIX GLYCOPROTEIN RELATED HEMOLECTIN, ISOFORM A structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC120839841|UniProtKB=A0ACM8EMW3 A0ACM8EMW3 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835338|UniProtKB=A0ACM8FTK8 A0ACM8FTK8 LOC121835338 PTHR10920:SF12 RIBOSOMAL RNA METHYLTRANSFERASE TRNA (CYTIDINE(32)_GUANOSINE(34)-2'-O)-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;methylation#GO:0032259;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC120844094|UniProtKB=A0ACM8EXU5 A0ACM8EXU5 LOC120844094 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8042779|UniProtKB=A0ACM8E4L5 A0ACM8E4L5 Mgat4a PTHR12062:SF9 N-ACETYLGLUCOSAMINYLTRANSFERASE VI ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE A, ISOFORM A-RELATED hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi stack#GO:0005795;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;Golgi apparatus subcompartment#GO:0098791 transferase#PC00220 IXOSC|EnsemblGenome=LOC8039586|UniProtKB=A0ACM8EAA4 A0ACM8EAA4 PTHR10928:SF2 SUPPRESSOR OF FUSED SUPPRESSOR OF FUSED HOMOLOG protein sequestering activity#GO:0140311;molecular sequestering activity#GO:0140313 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;negative regulation of response to stimulus#GO:0048585;regulation of nucleobase-containing compound metabolic process#GO:0019219 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 Hedgehog signaling pathway#P00025>Su(fu)#P00699 IXOSC|EnsemblGenome=LOC121834545|UniProtKB=A0ACM8FQA5 A0ACM8FQA5 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121833467|UniProtKB=A0ACM8FL72 A0ACM8FL72 LOC121833467 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120839807|UniProtKB=A0ACM8G3S0 A0ACM8G3S0 LOC120839807 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053858|UniProtKB=A0ACM8E416 A0ACM8E416 LOC8053858 PTHR12475:SF4 FAMILY NOT NAMED PROTEIN THEM6 IXOSC|EnsemblGenome=LOC8034325|UniProtKB=A0ACM8FLS5 A0ACM8FLS5 PTHR24051:SF9 SUSHI DOMAIN-CONTAINING PROTEIN 1 FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN extracellular matrix glycoprotein#PC00100 IXOSC|EnsemblGenome=LOC115316128|UniProtKB=A0ACM8DW03 A0ACM8DW03 LOC115316128 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121838482|UniProtKB=A0ACM8G8E7 A0ACM8G8E7 LOC121838482 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8042156|UniProtKB=A0ACM8E2P8 A0ACM8E2P8 Pka-C3 PTHR24353:SF160 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT PRKX transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell adhesion#GO:0007155;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;GABA-B receptor II signaling#P05731>PKA#P05752;Endothelin signaling pathway#P00019>PKA#P00570;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862 IXOSC|EnsemblGenome=LOC8024664|UniProtKB=A0ACM8G249 A0ACM8G249 LOC8024664 PTHR24252:SF33 ACROSIN-RELATED PROCLOTTING ENZYME-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8053051|UniProtKB=A0ACM8DPY2 A0ACM8DPY2 LOC8053051 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115329822|UniProtKB=A0ACM8ER01 A0ACM8ER01 LOC115329822 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121833582|UniProtKB=A0ACM8FLW8 A0ACM8FLW8 LOC121833582 PTHR39387:SF1 SHAVENOID, ISOFORM B PROTEIN KINASE DOMAIN-CONTAINING PROTEIN developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;epidermis development#GO:0008544;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;cellular process#GO:0009987;tissue development#GO:0009888;epidermal cell differentiation#GO:0009913;epithelial cell differentiation#GO:0030855;cell differentiation#GO:0030154;epithelium development#GO:0060429 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938 IXOSC|EnsemblGenome=LOC8036556|UniProtKB=A0ACM8FBL8 A0ACM8FBL8 LOC8036556 PTHR45775:SF6 RAD, GEM/KIR FAMILY MEMBER 2, ISOFORM C RAD, GEM_KIR FAMILY MEMBER 2, ISOFORM C IXOSC|EnsemblGenome=LOC115310988|UniProtKB=A0ACM8DQ82 A0ACM8DQ82 LOC115310988 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8029209|UniProtKB=A0ACM8DQM0 A0ACM8DQM0 LOC8029209 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8042685|UniProtKB=A0ACM8F1C6 A0ACM8F1C6 LOC8042685 PTHR12231:SF278 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN KAPPA, ISOFORM A binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;cell adhesion#GO:0007155;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cell junction#GO:0030054;cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC120847643|UniProtKB=A0ACM8F4E7 A0ACM8F4E7 LOC120847643 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051906|UniProtKB=A0ACM8DTJ3 A0ACM8DTJ3 LOC8051906 PTHR33538:SF7 PROTEIN GAMETE EXPRESSED 1 PROTEIN BRAMBLEBERRY IXOSC|EnsemblGenome=LOC8029394|UniProtKB=A0ACM8FHK3 A0ACM8FHK3 LOC8029394 PTHR45655:SF5 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 SOLUBLE GUANYLATE CYCLASE 89DA-RELATED guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824 response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;cytosol#GO:0005829 guanylate cyclase#PC00114;cyclase#PC00079 IXOSC|EnsemblGenome=LOC121834885|UniProtKB=A0ACM8FQR0 A0ACM8FQR0 LOC121834885 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN developmental process#GO:0032502;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular process#GO:0009987;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC120848171|UniProtKB=A0ACM8G5A4 A0ACM8G5A4 LOC120848171 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329104|UniProtKB=A0ACM8G0Q2 A0ACM8G0Q2 LOC115329104 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027135|UniProtKB=A0ACM8FVP8 A0ACM8FVP8 LOC8027135 PTHR24264:SF91 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115310529|UniProtKB=A0ACM8EEV3 A0ACM8EEV3 LOC115310529 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115329636|UniProtKB=A0ACM8E9X2 A0ACM8E9X2 sxc PTHR44998:SF1 FAMILY NOT NAMED UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 IXOSC|EnsemblGenome=LOC8027089|UniProtKB=A0ACM8FUN3 A0ACM8FUN3 LOC8027089 PTHR11686:SF77 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120841045|UniProtKB=A0ACM8ER21 A0ACM8ER21 LOC120841045 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8032483|UniProtKB=A0ACM8DXC9 A0ACM8DXC9 LOC8032483 PTHR10933:SF9 IMMUNOGLOBULIN-BINDING PROTEIN 1 IMMUNOGLOBULIN BINDING PROTEIN 1 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;TOR signaling#GO:0031929;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115310616|UniProtKB=A0ACM8EYQ4 A0ACM8EYQ4 LOC115310616 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120850830|UniProtKB=A0ACM8FB65 A0ACM8FB65 LOC120850830 PTHR23123:SF38 PHD/F-BOX CONTAINING PROTEIN JMJC DOMAIN-CONTAINING PROTEIN-RELATED histone modifying activity#GO:0140993;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC115318458|UniProtKB=A0ACM8DYK5 A0ACM8DYK5 LOC115318458 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200 IXOSC|EnsemblGenome=LOC8035128|UniProtKB=A0ACM8FU69 A0ACM8FU69 LOC8035128 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC8028737|UniProtKB=A0ACM8FC03 A0ACM8FC03 LOC8028737 PTHR24058:SF112 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 3 HOMOLOG-RELATED catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8036202|UniProtKB=A0ACM8DJX5 A0ACM8DJX5 LOC8036202 PTHR13460:SF0 FAMILY NOT NAMED MALECTIN binding#GO:0005488;carbohydrate binding#GO:0030246 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115324762|UniProtKB=A0ACM8ESI4 A0ACM8ESI4 LOC115324762 PTHR47143:SF3 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS ION_TRANS DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 transmembrane transporter complex#GO:1902495;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020 ion channel#PC00133 IXOSC|EnsemblGenome=LOC115318157|UniProtKB=A0ACM8FUE6 A0ACM8FUE6 LOC115318157 PTHR13005:SF4 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120838765|UniProtKB=A0ACM8FCI8 A0ACM8FCI8 PTHR11109:SF7 GTP CYCLOHYDROLASE I GTP CYCLOHYDROLASE 1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Tetrahydrofolate biosynthesis#P02742>GTP cyclohydrolase#P02951 IXOSC|EnsemblGenome=LOC8025586|UniProtKB=A0ACM8DTM9 A0ACM8DTM9 Taf2 PTHR15137:SF9 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;transferase complex#GO:1990234 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 IXOSC|EnsemblGenome=LOC120843864|UniProtKB=A0ACM8ECD9 A0ACM8ECD9 LOC8036686 PTHR45625:SF18 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 1 catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115324717|UniProtKB=A0ACM8E4Y2 A0ACM8E4Y2 LOC115324717 PTHR45683:SF18 MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 32 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC8052620|UniProtKB=A0ACM8ECE6 A0ACM8ECE6 LOC8052620 PTHR10827:SF78 RETICULOCALBIN RETICULOCALBIN-2 binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 calcium-binding protein#PC00060;calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC115319328|UniProtKB=A0ACM8DYY7 A0ACM8DYY7 LOC115319328 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027349|UniProtKB=A0ACM8FD24 A0ACM8FD24 LOC8027349 PTHR10367:SF17 MRNA-CAPPING ENZYME MRNA-CAPPING ENZYME catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 RNA processing factor#PC00147;mRNA capping factor#PC00145 IXOSC|EnsemblGenome=LOC8041491|UniProtKB=A0ACM8ET47 A0ACM8ET47 LOC8041491 PTHR12363:SF42 TRANSPORTIN 3 AND IMPORTIN 13 TRANSPORTIN-3 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC8043205|UniProtKB=A0ACM8DL22 A0ACM8DL22 LOC8043205 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8040455|UniProtKB=A0ACM8EEH4 A0ACM8EEH4 LOC8040455 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 IXOSC|EnsemblGenome=LOC8037338|UniProtKB=A0ACM8DX50 A0ACM8DX50 LOC8037338 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8025667|UniProtKB=A0ACM8E865 A0ACM8E865 l(1)G0020 PTHR10925:SF5 N-ACETYLTRANSFERASE 10 RNA CYTIDINE ACETYLTRANSFERASE catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;catalytic activity, acting on RNA#GO:0140098;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA modification#GO:0006400;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 organelle lumen#GO:0043233;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120849019|UniProtKB=A0ACM8F7T2 A0ACM8F7T2 LOC120849019 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024605|UniProtKB=A0ACM8G175 A0ACM8G175 Shal PTHR11537:SF105 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAL monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244 transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;action potential#GO:0001508;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 ion channel#PC00133;voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC115318862|UniProtKB=A0ACM8EMQ5 A0ACM8EMQ5 LOC115318862 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120837018|UniProtKB=A0ACM8EGE3 A0ACM8EGE3 LOC120837018 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038806|UniProtKB=A0ACM8FTM1 A0ACM8FTM1 Ythdc1 PTHR12357:SF3 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING PROTEIN 1 protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090;mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 gene expression#GO:0010467;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;nucleic acid biosynthetic process#GO:0141187;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of mRNA splicing, via spliceosome#GO:0048024;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions#GO:0000375 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115329817|UniProtKB=A0ACM8EA15 A0ACM8EA15 LOC115329817 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115319497|UniProtKB=A0ACM8E093 A0ACM8E093 LOC115319497 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC115327224|UniProtKB=A0ACM8F5H3 A0ACM8F5H3 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC121836609|UniProtKB=A0ACM8G0M6 A0ACM8G0M6 LOC121836609 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8033780|UniProtKB=A0ACM8DPC0 A0ACM8DPC0 LOC8033780 PTHR32546:SF16 G-PROTEIN COUPLED RECEPTOR 158-RELATED G-PROTEIN COUPLED RECEPTOR CG31760-RELATED G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8035679|UniProtKB=A0ACM8EWY3 A0ACM8EWY3 LOC8035679 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115329086|UniProtKB=A0ACM8ELS4 A0ACM8ELS4 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030984|UniProtKB=A0ACM8F712 A0ACM8F712 LOC8030984 PTHR11267:SF181 T-BOX PROTEIN-RELATED OPTOMOTOR-BLIND PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 IXOSC|EnsemblGenome=LOC8041398|UniProtKB=A0ACM8DKN7 A0ACM8DKN7 LOC8041398 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8034979|UniProtKB=A0ACM8E280 A0ACM8E280 snRNP-U1-C PTHR31148:SF1 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C U1 SMALL NUCLEAR RIBONUCLEOPROTEIN C RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;cellular component assembly#GO:0022607;gene expression#GO:0010467;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 U1 snRNP#GO:0005685;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115310795|UniProtKB=A0ACM8F4P2 A0ACM8F4P2 LOC115310795 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115323238|UniProtKB=A0ACM8E3J1 A0ACM8E3J1 LOC115323238 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120845186|UniProtKB=A0ACM8EZM9 A0ACM8EZM9 LOC120845186 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8038393|UniProtKB=A0ACM8F9Z5 A0ACM8F9Z5 Mat89Ba PTHR17972:SF0 NUCLEOLAR RNA-ASSOCIATED PROTEIN NUCLEOLAR PROTEIN 6 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;90S preribosome#GO:0030686;small-subunit processome#GO:0032040;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115325315|UniProtKB=A0ACM8EM52 A0ACM8EM52 LOC115325315 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115327246|UniProtKB=A0ACM8E7T5 A0ACM8E7T5 LOC115327246 PTHR11875:SF7 TESTIS-SPECIFIC Y-ENCODED PROTEIN AT14585P-RELATED histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;protein binding#GO:0005515 chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115331537|UniProtKB=A0ACM8ET29 A0ACM8ET29 LOC115331537 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847120|UniProtKB=A0ACM8FMI3 A0ACM8FMI3 PTHR10574:SF449 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cellular process#GO:0009987;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 IXOSC|EnsemblGenome=LOC8034943|UniProtKB=A0ACM8FHE6 A0ACM8FHE6 LOC8034943 PTHR11690:SF248 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC121835619|UniProtKB=A0ACM8FW97 A0ACM8FW97 LOC121835619 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115316830|UniProtKB=A0ACM8ERV9 A0ACM8ERV9 LOC115316830 PTHR10579:SF178 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-LIKE ion channel#PC00133 IXOSC|EnsemblGenome=LOC8032277|UniProtKB=A0ACM8FTS0 A0ACM8FTS0 LOC8032277 PTHR12011:SF347 ADHESION G-PROTEIN COUPLED RECEPTOR LATROPHILIN CIRL plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120843559|UniProtKB=A0ACM8EWD9 A0ACM8EWD9 LOC120843559 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313327|UniProtKB=A0ACM8EGH1 A0ACM8EGH1 LOC115313327 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121046801|UniProtKB=A0ACM8FES2 A0ACM8FES2 LOC121046801 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC121833812|UniProtKB=A0ACM8FLT3 A0ACM8FLT3 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC115319475|UniProtKB=A0ACM8E084 A0ACM8E084 LOC115319475 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8041205|UniProtKB=A0ACM8F660 A0ACM8F660 LOC8041205 PTHR43127:SF2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 DEVELOPMENTALLY-REGULATED GTP-BINDING PROTEIN 2 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8026921|UniProtKB=A0ACM8FSE4 A0ACM8FSE4 LOC8026921 PTHR23122:SF14 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PROTEIN PALS1 embryo development#GO:0009790;nervous system development#GO:0007399;epithelium development#GO:0060429;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;morphogenesis of an epithelium#GO:0002009;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;cellular developmental process#GO:0048869;developmental process#GO:0032502;protein localization to cell periphery#GO:1990778;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;system development#GO:0048731;tissue morphogenesis#GO:0048729;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;anatomical structure development#GO:0048856;cellular localization#GO:0051641;generation of neurons#GO:0048699;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of apical/basal cell polarity#GO:0035088 cell junction#GO:0030054;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115320806|UniProtKB=A0ACM8E1L7 A0ACM8E1L7 LOC115320806 PTHR10802:SF2 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM40 HOMOLOG 1-RELATED transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein localization to mitochondrion#GO:0070585;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115311258|UniProtKB=A0ACM8F2A8 A0ACM8F2A8 LOC115311258 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8024019|UniProtKB=A0ACM8DSZ6 A0ACM8DSZ6 LOC8024019 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC8042900|UniProtKB=A0ACM8DRB9 A0ACM8DRB9 Mcm3 PTHR11630:SF46 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM3-RELATED ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 MCM complex#GO:0042555;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8043234|UniProtKB=A0ACM8DSC0 A0ACM8DSC0 LOC8043234 PTHR10196:SF68 SUGAR KINASE GLYCEROL KINASE 5 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;alcohol metabolic process#GO:0006066;neutral lipid metabolic process#GO:0006638;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 carbohydrate kinase#PC00065;kinase#PC00137 IXOSC|EnsemblGenome=LOC115321643|UniProtKB=A0ACM8EF22 A0ACM8EF22 LOC115321643 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8028663|UniProtKB=A0ACM8DN86 A0ACM8DN86 LOC8028663 PTHR28441:SF2 PROTEIN FAM91A1 PROTEIN FAM91A1 IXOSC|EnsemblGenome=LOC115313305|UniProtKB=A0ACM8FH21 A0ACM8FH21 LOC115313305 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115328857|UniProtKB=A0ACM8F4I0 A0ACM8F4I0 LOC115328857 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318470|UniProtKB=A0ACM8DXX8 A0ACM8DXX8 LOC115318470 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120849822|UniProtKB=A0ACM8FL94 A0ACM8FL94 LOC120849822 PTHR24072:SF411 RHO FAMILY GTPASE RAS-RELATED PROTEIN RAC1-RELATED small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 regulation of locomotion#GO:0040012;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;neurogenesis#GO:0022008;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;signal transduction#GO:0007165;cell projection assembly#GO:0030031;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;cell development#GO:0048468;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;regulation of cytoskeleton organization#GO:0051493;intracellular signal transduction#GO:0035556;system development#GO:0048731;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;regulation of cell motility#GO:2000145;cortical cytoskeleton organization#GO:0030865;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;signaling#GO:0023052;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;Rac protein signal transduction#GO:0016601;generation of neurons#GO:0048699;establishment or maintenance of cell polarity#GO:0007163 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 G-protein#PC00020;small GTPase#PC00208 Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;Axon guidance mediated by netrin#P00009>Rac#P00366;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;Integrin signalling pathway#P00034>Rac#P00927;Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;T cell activation#P00053>rac#P01324;EGF receptor signaling pathway#P00018>Rac#P00564;FGF signaling pathway#P00021>Rac#P00645 IXOSC|EnsemblGenome=LOC8031015|UniProtKB=A0ACM8EI22 A0ACM8EI22 LOC8031015 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120842511|UniProtKB=A0ACM8ETZ4 A0ACM8ETZ4 LOC120842511 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120837396|UniProtKB=A0ACM8EI94 A0ACM8EI94 LOC120837396 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8039136|UniProtKB=A0ACM8FFU9 A0ACM8FFU9 LOC8039136 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8029248|UniProtKB=A0ACM8DHV8 A0ACM8DHV8 LOC8029248 PTHR23151:SF92 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED PYRUVATE DEHYDROGENASE PROTEIN X COMPONENT, MITOCHONDRIAL acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204 acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC8038793|UniProtKB=A0ACM8E8H0 A0ACM8E8H0 TM9SF3 PTHR10766:SF41 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 3 intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8032721|UniProtKB=A0ACM8F785 A0ACM8F785 LOC8032721 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8054055|UniProtKB=A0ACM8EER3 A0ACM8EER3 LOC8054055 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121837650|UniProtKB=A0ACM8G5R9 A0ACM8G5R9 LOC121837650 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030072|UniProtKB=A0ACM8DWH2 A0ACM8DWH2 LOC8030072 PTHR10528:SF17 AF4/FMR2 FAMILY MEMBER AF4_FMR2 FAMILY MEMBER LILLI transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;RNA metabolic process#GO:0016070;regulation of RNA metabolic process#GO:0051252;nucleic acid biosynthetic process#GO:0141187;nervous system process#GO:0050877;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;system process#GO:0003008;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8027257|UniProtKB=A0ACM8G3X4 A0ACM8G3X4 LOC8027257 PTHR12053:SF4 PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED CARBOXYPEPTIDASE Q catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;peptidase activity#GO:0008233 catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8052501|UniProtKB=A0ACM8DPB3 A0ACM8DPB3 Cluap1 PTHR21547:SF0 CLUSTERIN ASSOCIATED PROTEIN 1 CLUSTERIN-ASSOCIATED PROTEIN 1 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992 IXOSC|EnsemblGenome=LOC115318813|UniProtKB=A0ACM8F2C5 A0ACM8F2C5 LOC115318813 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8040358|UniProtKB=A0ACM8DSF9 A0ACM8DSF9 LOC8040358 PTHR10250:SF26 MICROSOMAL GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE 3, MITOCHONDRIAL oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;glutathione transferase activity#GO:0004364;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;transferase activity#GO:0016740;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 nucleus#GO:0005634;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220 IXOSC|EnsemblGenome=LOC8027923|UniProtKB=A0ACM8E7Q7 A0ACM8E7Q7 LOC8027923 PTHR16320:SF24 SPHINGOMYELINASE FAMILY MEMBER ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028641|UniProtKB=A0ACM8FFK4 A0ACM8FFK4 LOC8028641 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 lipid localization#GO:0010876;ceramide metabolic process#GO:0006672;localization#GO:0051179;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;transport#GO:0006810;lipid metabolic process#GO:0006629;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;lipid transport#GO:0006869 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121834561|UniProtKB=A0ACM8FQ28 A0ACM8FQ28 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039835|UniProtKB=A0ACM8F682 A0ACM8F682 LOC8039835 PTHR24333:SF9 HOMEO BOX HB9 LIKE A-RELATED HOMEOBOX DOMAIN-CONTAINING PROTEIN homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC120838952|UniProtKB=A0ACM8EL44 A0ACM8EL44 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842024|UniProtKB=A0ACM8ESW9 A0ACM8ESW9 LOC120842024 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841334|UniProtKB=A0ACM8G1M2 A0ACM8G1M2 LOC120841334 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323629|UniProtKB=A0ACM8E3V0 A0ACM8E3V0 LOC115323629 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC8040621|UniProtKB=A0ACM8DGZ8 A0ACM8DGZ8 PTHR12223:SF45 VESICULAR MANNOSE-BINDING LECTIN RE50040P binding#GO:0005488;small molecule binding#GO:0036094;monosaccharide binding#GO:0048029;carbohydrate binding#GO:0030246 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120850103|UniProtKB=A0ACM8FA12 A0ACM8FA12 LOC120850103 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031533|UniProtKB=A0ACM8F8P9 A0ACM8F8P9 LOC8031533 PTHR43615:SF1 PHOSPHOENOLPYRUVATE SYNTHASE-RELATED PHOSPHOENOLPYRUVATE SYNTHASE IXOSC|EnsemblGenome=LOC8053251|UniProtKB=A0ACM8DGX9 A0ACM8DGX9 LOC8053251 PTHR13619:SF0 PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL PHOSPHATIDATE CYTIDYLYLTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phosphatidylglycerol biosynthetic process#GO:0006655;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8027106|UniProtKB=A0ACM8E9H5 A0ACM8E9H5 LOC8027106 PTHR13793:SF150 PHD FINGER PROTEINS PHD FINGER PROTEIN 14 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566;chromatin-protein adaptor activity#GO:0140463 chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120847464|UniProtKB=A0ACM8F427 A0ACM8F427 LOC120847464 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328948|UniProtKB=A0ACM8EMG8 A0ACM8EMG8 LOC115328948 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121046918|UniProtKB=A0ACM8FF55 A0ACM8FF55 LOC121046918 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115327344|UniProtKB=A0ACM8F4J7 A0ACM8F4J7 LOC115327344 PTHR46212:SF11 PEFLIN PEFLIN IXOSC|EnsemblGenome=LOC8031470|UniProtKB=A0ACM8ER25 A0ACM8ER25 LOC8031470 PTHR11686:SF77 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC115323137|UniProtKB=A0ACM8E2Q3 A0ACM8E2Q3 LOC115323137 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846496|UniProtKB=A0ACM8F279 A0ACM8F279 LOC120846496 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839686|UniProtKB=A0ACM8FE07 A0ACM8FE07 LOC120839686 PTHR24198:SF196 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ZU5 DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8033495|UniProtKB=A0ACM8DI21 A0ACM8DI21 LOC8033495 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115308519|UniProtKB=A0ACM8FMQ5 A0ACM8FMQ5 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039651|UniProtKB=A0ACM8DKF1 A0ACM8DKF1 LOC8039651 PTHR11929:SF249 ALPHA- 1,3 -FUCOSYLTRANSFERASE FUCOSYLTRANSFERASE alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120836359|UniProtKB=A0ACM8F774 A0ACM8F774 LOC8052273 PTHR18919:SF153 ACETYL-COA C-ACYLTRANSFERASE TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120849006|UniProtKB=A0ACM8F6V6 A0ACM8F6V6 LOC120849006 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042567|UniProtKB=A0ACM8EH49 A0ACM8EH49 Hip1 PTHR10407:SF15 HUNTINGTIN INTERACTING PROTEIN 1 HUNTINGTIN INTERACTING PROTEIN 1 phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;cytoskeletal adaptor activity#GO:0008093;protein binding#GO:0005515;lipid binding#GO:0008289;protein-membrane adaptor activity#GO:0043495;protein-containing complex binding#GO:0044877;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015 transport#GO:0006810;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;localization#GO:0051179;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036 membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;vesicle#GO:0031982;cell cortex#GO:0005938;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;clathrin-coated vesicle#GO:0030136;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;cell periphery#GO:0071944 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC115320467|UniProtKB=A0ACM8E0T3 A0ACM8E0T3 LOC115320467 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8031233|UniProtKB=A0ACM8G219 A0ACM8G219 LOC8031233 PTHR21974:SF2 RE15880P RE15880P cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929 IXOSC|EnsemblGenome=LOC121834577|UniProtKB=A0ACM8FQQ8 A0ACM8FQQ8 LOC8024445 PTHR48028:SF8 GLYCINE-RICH RNA-BINDING PROTEIN RZ1A RRM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842871|UniProtKB=A0ACM8EUM4 A0ACM8EUM4 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041433|UniProtKB=A0ACM8DKQ2 A0ACM8DKQ2 LOC8041433 PTHR12192:SF26 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 1 catalytic activity#GO:0003824;lyase activity#GO:0016829 cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8031126|UniProtKB=A0ACM8FGX8 A0ACM8FGX8 LOC8031126 PTHR43450:SF1 ASPARTYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8032719|UniProtKB=A0ACM8FZX1 A0ACM8FZX1 LOC8032719 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120844133|UniProtKB=A0ACM8EXX2 A0ACM8EXX2 LOC120844133 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043935|UniProtKB=A0ACM8FP33 A0ACM8FP33 PTHR12231:SF283 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8023163|UniProtKB=A0ACM8E8J2 A0ACM8E8J2 Rac1 PTHR24072:SF411 RHO FAMILY GTPASE RAS-RELATED PROTEIN RAC1-RELATED nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001 axon guidance#GO:0007411;multicellular organismal process#GO:0032501;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cell projection assembly#GO:0030031;signal transduction#GO:0007165;cellular process#GO:0009987;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin filament-based process#GO:0032970;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;regulation of developmental process#GO:0050793;cortical cytoskeleton organization#GO:0030865;regulation of cell motility#GO:2000145;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;system development#GO:0048731;intracellular signal transduction#GO:0035556;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;cell differentiation#GO:0030154;cell projection organization#GO:0030030;signaling#GO:0023052;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;Rac protein signal transduction#GO:0016601 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856 small GTPase#PC00208;G-protein#PC00020 Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;Axon guidance mediated by netrin#P00009>Rac#P00366;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;Integrin signalling pathway#P00034>Rac#P00927;Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;T cell activation#P00053>rac#P01324;EGF receptor signaling pathway#P00018>Rac#P00564;FGF signaling pathway#P00021>Rac#P00645 IXOSC|EnsemblGenome=LOC115326201|UniProtKB=A0ACM8E5M8 A0ACM8E5M8 LOC115326201 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032615|UniProtKB=A0ACM8DR51 A0ACM8DR51 Atg1 PTHR24348:SF79 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED AUTOPHAGY-RELATED 1, ISOFORM B catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;macroautophagy#GO:0016236;response to nutrient levels#GO:0031667;reticulophagy#GO:0061709;regulation of metabolic process#GO:0019222;axon development#GO:0061564;mitophagy#GO:0000423;cellular developmental process#GO:0048869;developmental growth#GO:0048589;regulation of catabolic process#GO:0009894;neurogenesis#GO:0022008;autophagy of mitochondrion#GO:0000422;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;piecemeal microautophagy of the nucleus#GO:0034727;developmental cell growth#GO:0048588;response to starvation#GO:0042594;anatomical structure development#GO:0048856;vacuole organization#GO:0007033;system development#GO:0048731;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;axon extension#GO:0048675;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell growth#GO:0016049;cell projection morphogenesis#GO:0048858;autophagosome assembly#GO:0000045;metabolic process#GO:0008152;neuron differentiation#GO:0030182;growth#GO:0040007;plasma membrane bounded cell projection morphogenesis#GO:0120039;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;neuron development#GO:0048666;process utilizing autophagic mechanism#GO:0061919;axonogenesis#GO:0007409;neuron projection extension#GO:1990138;developmental growth involved in morphogenesis#GO:0060560;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115316197|UniProtKB=A0ACM8FNZ8 A0ACM8FNZ8 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330948|UniProtKB=A0ACM8FTI3 A0ACM8FTI3 LOC115330948 PTHR22599:SF11 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR-LIKE 3 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC120837141|UniProtKB=A0ACM8EGR2 A0ACM8EGR2 LOC120837141 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE peptidase activity#GO:0008233;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule catabolic process#GO:0044282;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115323870|UniProtKB=A0ACM8E3G9 A0ACM8E3G9 LOC115323870 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115329368|UniProtKB=A0ACM8G663 A0ACM8G663 LOC115329368 PTHR11958:SF99 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;carboxylic acid transport#GO:0046942;transport#GO:0006810;acidic amino acid transport#GO:0015800;organic acid transport#GO:0015849;amino acid transport#GO:0006865;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 IXOSC|EnsemblGenome=LOC120848849|UniProtKB=A0ACM8F5P3 A0ACM8F5P3 LOC120848849 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8026319|UniProtKB=A0ACM8ET35 A0ACM8ET35 PTHR24416:SF489 TYROSINE-PROTEIN KINASE RECEPTOR PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120849275|UniProtKB=A0ACM8F7T5 A0ACM8F7T5 LOC120849275 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8042880|UniProtKB=A0ACM8FUQ8 A0ACM8FUQ8 LOC8042880 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115321226|UniProtKB=A0ACM8E1S5 A0ACM8E1S5 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8033686|UniProtKB=A0ACM8DR79 A0ACM8DR79 LOC8033686 PTHR11347:SF198 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC-AMP PHOSPHODIESTERASE, ISOFORM I hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 hydrolase#PC00121;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC115308416|UniProtKB=A0ACM8EW69 A0ACM8EW69 LOC115308416 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849220|UniProtKB=A0ACM8FS38 A0ACM8FS38 LOC120849220 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8028680|UniProtKB=A0ACM8E9X1 A0ACM8E9X1 siz PTHR10663:SF342 GUANYL-NUCLEOTIDE EXCHANGE FACTOR FI21420P1 regulation of biological quality#GO:0065008;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100;regulation of cellular process#GO:0050794;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC120839794|UniProtKB=A0ACM8ENQ0 A0ACM8ENQ0 LOC120839794 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8033158|UniProtKB=A0ACM8FHV8 A0ACM8FHV8 LOC8033158 PTHR24043:SF9 SCAVENGER RECEPTOR CLASS F MULTIPLE EGF LIKE DOMAINS 11 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120846929|UniProtKB=A0ACM8F4F1 A0ACM8F4F1 LOC120846929 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848097|UniProtKB=A0ACM8F652 A0ACM8F652 LOC120848097 PTHR23359:SF206 NUCLEOTIDE KINASE UMP-CMP KINASE nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, phosphate group as acceptor#GO:0016776 nucleoside diphosphate metabolic process#GO:0009132;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896;Salvage pyrimidine ribonucleotides#P02775>Cytidylate kinase#P03153;De novo pyrimidine ribonucleotides biosythesis#P02740>Uridylate kinase#P02924 IXOSC|EnsemblGenome=LOC120840449|UniProtKB=A0ACM8G532 A0ACM8G532 LOC120840449 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8028717|UniProtKB=A0ACM8ECB8 A0ACM8ECB8 LOC8028717 PTHR13452:SF10 THUMP DOMAIN CONTAINING PROTEIN 1-RELATED THUMP DOMAIN-CONTAINING PROTEIN 1 protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 IXOSC|EnsemblGenome=LOC8029934|UniProtKB=A0ACM8E0F5 A0ACM8E0F5 LOC8029934 PTHR23058:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX14 PEROXISOMAL MEMBRANE PROTEIN PEX14 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;peroxisomal transport#GO:0043574;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;peroxisome organization#GO:0007031;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;transporter complex#GO:1990351;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8035813|UniProtKB=A0ACM8DGZ3 A0ACM8DGZ3 ND-23 PTHR10849:SF20 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 8, MITOCHONDRIAL NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 8, MITOCHONDRIAL catalytic activity#GO:0003824;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115325109|UniProtKB=A0ACM8EWP4 A0ACM8EWP4 LOC115325109 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8038567|UniProtKB=A0ACM8DK65 A0ACM8DK65 MED10 PTHR13345:SF13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8030678|UniProtKB=A0ACM8E8V7 A0ACM8E8V7 PTHR11590:SF40 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE HEMOCYTE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 IXOSC|EnsemblGenome=LOC120845995|UniProtKB=A0ACM8F159 A0ACM8F159 LOC120845995 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8028002|UniProtKB=A0ACM8FTR2 A0ACM8FTR2 LOC8028002 PTHR23079:SF55 RNA-DEPENDENT RNA POLYMERASE RNA-DIRECTED RNA POLYMERASE catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;siRNA processing#GO:0030422;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8037994|UniProtKB=A0ACM8DIE9 A0ACM8DIE9 PTHR19370:SF219 NADH-CYTOCHROME B5 REDUCTASE NADH-CYTOCHROME B5 REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;oxidoreductase activity, acting on NAD(P)H#GO:0016651 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 reductase#PC00198;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121836804|UniProtKB=A0ACM8G0M8 A0ACM8G0M8 LOC121836804 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC121835710|UniProtKB=A0ACM8FW89 A0ACM8FW89 LOC121835710 PTHR34179:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120848454|UniProtKB=A0ACM8F627 A0ACM8F627 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8033565|UniProtKB=A0ACM8FLI9 A0ACM8FLI9 Oseg1 PTHR12764:SF4 WD REPEAT DOMAIN-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 122 HOMOLOG microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular localization#GO:0051641;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;protein localization to organelle#GO:0033365;microtubule-based movement#GO:0007018;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;non-motile cilium#GO:0097730;cilium#GO:0005929;intraciliary transport particle#GO:0030990 IXOSC|EnsemblGenome=LOC8027990|UniProtKB=A0ACM8E6D0 A0ACM8E6D0 LOC8027990 PTHR11695:SF649 ALCOHOL DEHYDROGENASE RELATED NAD(P)H OXIDOREDUCTASE RTN4IP1, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115326800|UniProtKB=A0ACM8ERQ3 A0ACM8ERQ3 LOC115326800 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8028018|UniProtKB=A0ACM8DPP2 A0ACM8DPP2 Nc73EF PTHR23152:SF4 2-OXOGLUTARATE DEHYDROGENASE 2-OXOGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033280|UniProtKB=A0ACM8E7H3 A0ACM8E7H3 LOC8033280 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8027970|UniProtKB=A0ACM8E6Y1 A0ACM8E6Y1 LOC8027970 PTHR45828:SF40 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC120846067|UniProtKB=A0ACM8F169 A0ACM8F169 LOC120846067 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042432|UniProtKB=A0ACM8FCB3 A0ACM8FCB3 LOC8042432 PTHR45704:SF18 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE IXOSC|EnsemblGenome=LOC120841642|UniProtKB=A0ACM8ES31 A0ACM8ES31 LOC120841642 PTHR11690:SF305 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8051620|UniProtKB=A0ACM8EIT1 A0ACM8EIT1 Ptp36E PTHR19134:SF561 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN SDF-9-RELATED phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115332893|UniProtKB=A0ACM8F566 A0ACM8F566 LOC115332893 PTHR13268:SF0 BREAST CARCINOMA AMPLIFIED SEQUENCE 3 BCAS3 MICROTUBULE ASSOCIATED CELL MIGRATION FACTOR enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 macroautophagy#GO:0016236;response to stimulus#GO:0050896;catabolic process#GO:0009056;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;organelle organization#GO:0006996;response to starvation#GO:0042594;response to nutrient levels#GO:0031667;response to stress#GO:0006950;cellular component organization#GO:0016043;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152 phagophore assembly site#GO:0000407;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC8039330|UniProtKB=A0ACM8EEA5 A0ACM8EEA5 botv PTHR48261:SF2 ACETYLGLUCOSAMINYLTRANSFERASE GLUCURONOSYL-GALACTOSYL-PROTEOGLYCAN 4-ALPHA-N-ACETYLGLUCOSAMINYLTRANSFERASE IXOSC|EnsemblGenome=LOC8025939|UniProtKB=A0ACM8DZ81 A0ACM8DZ81 LOC8025939 PTHR24023:SF1089 COLLAGEN ALPHA COLLAGEN ALPHA-1(VII) CHAIN ISOFORM X1 structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cellular component organization#GO:0016043;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC121836815|UniProtKB=A0ACM8G088 A0ACM8G088 LOC121836815 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8027925|UniProtKB=A0ACM8DJF6 A0ACM8DJF6 kud PTHR13636:SF0 TRANSMEMBRANE PROTEIN 258 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT TMEM258 protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular response to stress#GO:0033554;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950;response to stimulus#GO:0050896 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC115313905|UniProtKB=A0ACM8EPB8 A0ACM8EPB8 LOC115313905 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120846571|UniProtKB=A0ACM8F2G2 A0ACM8F2G2 LOC120846571 PTHR10340:SF63 SPHINGOMYELIN PHOSPHODIESTERASE METALLOPHOS DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115316253|UniProtKB=A0ACM8EW68 A0ACM8EW68 PTHR19303:SF82 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120848514|UniProtKB=A0ACM8F515 A0ACM8F515 LOC120848514 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121836624|UniProtKB=A0ACM8FZH2 A0ACM8FZH2 LOC121836624 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848792|UniProtKB=A0ACM8F5K9 A0ACM8F5K9 LOC120848792 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326966|UniProtKB=A0ACM8F128 A0ACM8F128 LOC115326966 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to heat#GO:0009408;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein refolding#GO:0042026;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC120843595|UniProtKB=A0ACM8EWH6 A0ACM8EWH6 LOC120843595 PTHR33147:SF39 DEFENSIN-LIKE PROTEIN 1 DEFENSIN-LIKE PROTEIN 98 response to stress#GO:0006950;defense response#GO:0006952;response to stimulus#GO:0050896 antimicrobial response protein#PC00051 IXOSC|EnsemblGenome=LOC8038628|UniProtKB=A0ACM8E852 A0ACM8E852 LOC8038628 PTHR43016:SF16 PRESEQUENCE PROTEASE METALLOPROTEASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_4G07610)-RELATED metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115329280|UniProtKB=A0ACM8E9D0 A0ACM8E9D0 mats PTHR22599:SF74 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR-LIKE 1 enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;hippo signaling#GO:0035329;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8032546|UniProtKB=A0ACM8E2K5 A0ACM8E2K5 LOC8032546 PTHR24241:SF83 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 150-RELATED transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120846417|UniProtKB=A0ACM8F2B6 A0ACM8F2B6 LOC120846417 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842508|UniProtKB=A0ACM8ETS6 A0ACM8ETS6 LOC120842508 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8054067|UniProtKB=A0ACM8G490 A0ACM8G490 LOC8054067 PTHR11347:SF179 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC PHOSPHODIESTERASE PDE-3-RELATED cyclic-nucleotide phosphodiesterase activity#GO:0004112;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121837247|UniProtKB=A0ACM8G498 A0ACM8G498 LOC121837247 PTHR24340:SF73 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN BAGPIPE-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC120844726|UniProtKB=A0ACM8F0I0 A0ACM8F0I0 LOC120844726 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8027661|UniProtKB=A0ACM8E8S9 A0ACM8E8S9 LOC8027661 PTHR11240:SF22 RIBONUCLEASE T2 RIBONUCLEASE X25 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540 catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA catabolic process#GO:0006401 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC120837242|UniProtKB=A0ACM8EGH3 A0ACM8EGH3 LOC120837242 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837601|UniProtKB=A0ACM8G466 A0ACM8G466 LOC121837601 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC120835973|UniProtKB=A0ACM8EH19 A0ACM8EH19 LOC120835973 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120851190|UniProtKB=A0ACM8FCC7 A0ACM8FCC7 LOC120851190 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115330285|UniProtKB=A0ACM8EP60 A0ACM8EP60 LOC115330285 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120838718|UniProtKB=A0ACM8EKH8 A0ACM8EKH8 LOC120838718 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115332445|UniProtKB=A0ACM8EE75 A0ACM8EE75 LOC115332445 PTHR24350:SF34 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;microtubule cytoskeleton organization#GO:0000226 chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8038218|UniProtKB=A0ACM8DGQ4 A0ACM8DGQ4 LOC8038218 PTHR43903:SF12 NEUROLIGIN CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;tight junction#GO:0070160;apical junction complex#GO:0043296;cell-cell junction#GO:0005911 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8036808|UniProtKB=A0ACM8E318 A0ACM8E318 LOC8036808 PTHR46560:SF2 CYPHER, ISOFORM B DUSKY-LIKE, ISOFORM A developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell morphogenesis#GO:0000902 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 IXOSC|EnsemblGenome=LOC8027173|UniProtKB=A0ACM8ENH0 A0ACM8ENH0 LOC8027173 PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;extracellular region#GO:0005576;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC120848159|UniProtKB=A0ACM8F6A1 A0ACM8F6A1 LOC120848159 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043605|UniProtKB=A0ACM8DGR7 A0ACM8DGR7 LOC8043605 PTHR31784:SF3 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 5 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 protein-containing complex#GO:0032991;BLOC-1 complex#GO:0031083;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC8035468|UniProtKB=A0ACM8G3Y2 A0ACM8G3Y2 LOC8035468 PTHR45820:SF9 FI23527P1 FI23527P1 zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 intracellular monoatomic ion homeostasis#GO:0006873;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;homeostatic process#GO:0042592;metal ion transport#GO:0030001;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;zinc ion transmembrane transport#GO:0071577;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;response to stress#GO:0006950;monoatomic ion homeostasis#GO:0050801;detoxification of inorganic compound#GO:0061687;cellular process#GO:0009987;response to chemical#GO:0042221;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;detoxification#GO:0098754;monoatomic cation transmembrane transport#GO:0098655;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;response to metal ion#GO:0010038;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121047705|UniProtKB=A0ACM8FGF7 A0ACM8FGF7 LOC121047705 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833162|UniProtKB=A0ACM8FJG9 A0ACM8FJG9 LOC121833162 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036160|UniProtKB=A0ACM8F538 A0ACM8F538 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE peptidase activity#GO:0008233;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121833064|UniProtKB=A0ACM8FJE1 A0ACM8FJE1 LOC121833064 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312184|UniProtKB=A0ACM8EJJ1 A0ACM8EJJ1 LOC115312184 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8031548|UniProtKB=A0ACM8E8W8 A0ACM8E8W8 LOC8031548 PTHR13483:SF3 BOX C_D SNORNA PROTEIN 1-RELATED BOX C_D SNORNA PROTEIN 1 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular component assembly#GO:0022607;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115327542|UniProtKB=A0ACM8FU31 A0ACM8FU31 LOC115327542 PTHR23417:SF16 3-DEOXY-D-MANNO-OCTULOSONIC-ACID TRANSFERASE/TRNA GUANINE-N 7 - -METHYLTRANSFERASE TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115323958|UniProtKB=A0ACM8EVQ3 A0ACM8EVQ3 LOC115323958 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 IXOSC|EnsemblGenome=LOC120844655|UniProtKB=A0ACM8F0A2 A0ACM8F0A2 LOC120844655 PTHR24253:SF153 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260;serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115311392|UniProtKB=A0ACM8FZQ8 A0ACM8FZQ8 LOC115311392 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8051129|UniProtKB=A0ACM8DLD8 A0ACM8DLD8 LOC8051129 PTHR12743:SF0 CYTOCHROME C1 HEME LYASE HOLOCYTOCHROME C-TYPE SYNTHASE lyase activity#GO:0016829;catalytic activity, acting on a protein#GO:0140096;carbon-sulfur lyase activity#GO:0016846;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 lyase#PC00144 IXOSC|EnsemblGenome=LOC120838450|UniProtKB=A0ACM8EK11 A0ACM8EK11 LOC120838450 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037618|UniProtKB=A0ACM8FJ10 A0ACM8FJ10 LOC8037618 PTHR12294:SF1 EF HAND DOMAIN FAMILY A1,A2-RELATED CALCIUM UPTAKE PROTEIN 1, MITOCHONDRIAL cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 homeostatic process#GO:0042592;metal ion transport#GO:0030001;mitochondrial calcium ion homeostasis#GO:0051560;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810 membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703;transporter complex#GO:1990351;organelle membrane#GO:0031090;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 calcium-binding protein#PC00060;calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8023276|UniProtKB=A0ACM8FMA7 A0ACM8FMA7 LOC8023276 PTHR13968:SF35 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RRM DOMAIN-CONTAINING PROTEIN RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8036464|UniProtKB=A0ACM8E4J6 A0ACM8E4J6 LOC8036464 PTHR23250:SF1 DYSFERLIN-RELATED TECTONIN BETA-PROPELLER REPEAT-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835149|UniProtKB=A0ACM8FT47 A0ACM8FT47 LOC121835149 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8033722|UniProtKB=A0ACM8E6M6 A0ACM8E6M6 LOC8033722 PTHR14270:SF0 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 NONSENSE-MEDIATED MRNA DECAY FACTOR SMG9 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC8036718|UniProtKB=A0ACM8ECP0 A0ACM8ECP0 LOC8036718 PTHR13318:SF289 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX DOMAIN-CONTAINING PROTEIN proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC8052369|UniProtKB=A0ACM8EBY6 A0ACM8EBY6 mRpL40 PTHR13359:SF2 39S RIBOSOMAL PROTEIN L40, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML40 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120850060|UniProtKB=A0ACM8FZE4 A0ACM8FZE4 LOC120850060 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8043961|UniProtKB=A0ACM8DZ93 A0ACM8DZ93 PTHR19359:SF164 CYTOCHROME B5 CYTOCHROME B5 TYPE B binding#GO:0005488;heme binding#GO:0020037;tetrapyrrole binding#GO:0046906 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;membrane#GO:0016020 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115310577|UniProtKB=A0ACM8ENX2 A0ACM8ENX2 LOC115310577 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115325698|UniProtKB=A0ACM8E5T2 A0ACM8E5T2 LOC115325698 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120849498|UniProtKB=A0ACM8F7W6 A0ACM8F7W6 LOC120849498 PTHR45639:SF4 HSC70CB, ISOFORM G-RELATED HSC70CB, ISOFORM G molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 Hsp70 family chaperone#PC00027;chaperone#PC00072 IXOSC|EnsemblGenome=LOC121835838|UniProtKB=A0ACM8FX52 A0ACM8FX52 LOC121835838 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315416|UniProtKB=A0ACM8EKC2 A0ACM8EKC2 LOC115315416 PTHR22427:SF7 GH15728P GH15728P IXOSC|EnsemblGenome=LOC8041378|UniProtKB=A0ACM8FB90 A0ACM8FB90 LOC8041378 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364 modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC120839085|UniProtKB=A0ACM8ELZ4 A0ACM8ELZ4 RhoGAP71E PTHR23179:SF27 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED RHO GTPASE ACTIVATING PROTEIN AT 71E, ISOFORM D enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC115327785|UniProtKB=A0ACM8G5V9 A0ACM8G5V9 LOC115327785 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037402|UniProtKB=A0ACM8DNW3 A0ACM8DNW3 LOC8037402 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC120844692|UniProtKB=A0ACM8G7F7 A0ACM8G7F7 LOC120844692 PTHR21255:SF7 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE PROTEIN 2B binding#GO:0005488;protein binding#GO:0005515 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC115309488|UniProtKB=A0ACM8EJL1 A0ACM8EJL1 LOC115309488 PTHR23255:SF68 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II BMP AND ACTIVIN MEMBRANE-BOUND INHIBITOR HOMOLOG transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transforming growth factor beta receptor activity#GO:0005024;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to growth factor stimulus#GO:0071363;pattern specification process#GO:0007389;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;dorsal/ventral pattern formation#GO:0009953;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;cellular response to BMP stimulus#GO:0071773;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;regionalization#GO:0003002;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 cell periphery#GO:0071944;signaling receptor complex#GO:0043235;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 serine/threonine protein kinase receptor#PC00205 IXOSC|EnsemblGenome=LOC120840480|UniProtKB=A0ACM8FP77 A0ACM8FP77 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120850246|UniProtKB=A0ACM8FAG0 A0ACM8FAG0 LOC120850246 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053596|UniProtKB=A0ACM8DP60 A0ACM8DP60 LOC8053596 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032971|UniProtKB=A0ACM8DN31 A0ACM8DN31 LOC8032971 PTHR17605:SF0 RIBOSOME BIOGENESIS PROTEIN BOP1 BLOCK OF PROLIFERATION 1 PROTEIN RIBOSOME BIOGENESIS PROTEIN BOP1 binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;RNA binding#GO:0003723 maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115320470|UniProtKB=A0ACM8G622 A0ACM8G622 LOC115320470 PTHR45957:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 regulation of chromosome segregation#GO:0051983;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of chromosome organization#GO:0033044;metabolic process#GO:0008152;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;protein modification by small protein conjugation or removal#GO:0070647;mitotic cell cycle phase transition#GO:0044772;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K11-linked ubiquitination#GO:0070979;cell cycle#GO:0007049;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cellular component organization#GO:0051128 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152 Cell cycle#P00013>APC#P00481 IXOSC|EnsemblGenome=LOC8030945|UniProtKB=A0ACM8DHQ9 A0ACM8DHQ9 LOC8030945 PTHR13428:SF12 INNER NUCLEAR MEMBRANE PROTEIN MAN1 LEM DOMAIN CONTAINING PROTEIN INNER NUCLEAR MEMBRANE PROTEIN MAN1 chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 membrane assembly#GO:0071709;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997 IXOSC|EnsemblGenome=LOC8053792|UniProtKB=A0ACM8E8U1 A0ACM8E8U1 LOC8053792 PTHR11254:SF340 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE APOPTOSIS-RESISTANT E3 UBIQUITIN PROTEIN LIGASE 1 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of apoptotic process#GO:0042981;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of cellular process#GO:0050794;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121833567|UniProtKB=A0ACM8FLP0 A0ACM8FLP0 LOC121833567 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837926|UniProtKB=A0ACM8G6R1 A0ACM8G6R1 LOC121837926 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035071|UniProtKB=A0ACM8E9Q4 A0ACM8E9Q4 Tip60 PTHR10615:SF219 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT5 N-acetyltransferase activity#GO:0008080;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139 organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137;Alzheimer disease-amyloid secretase pathway#P00003>Tip60#P00093 IXOSC|EnsemblGenome=LOC8050421|UniProtKB=A0ACM8G421 A0ACM8G421 LOC8050421 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8036092|UniProtKB=A0ACM8DJT8 A0ACM8DJT8 LOC8036092 PTHR13088:SF3 FAS APOPTOTIC INHIBITORY MOLECULE FAIM FAS APOPTOTIC INHIBITORY MOLECULE 1 regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of signaling#GO:0023051;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of programmed cell death#GO:0043069;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 IXOSC|EnsemblGenome=LOC8035454|UniProtKB=A0ACM8DJT4 A0ACM8DJT4 LOC8035454 PTHR11562:SF17 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER LD05335P monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;transport#GO:0006810;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC121837236|UniProtKB=A0ACM8G2X2 A0ACM8G2X2 LOC121837236 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308458|UniProtKB=A0ACM8EVG6 A0ACM8EVG6 LOC115308458 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8023544|UniProtKB=A0ACM8DSL2 A0ACM8DSL2 LOC8023544 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8053027|UniProtKB=A0ACM8DLJ2 A0ACM8DLJ2 Sbds PTHR10927:SF1 RIBOSOME MATURATION PROTEIN SBDS RIBOSOME MATURATION PROTEIN SBDS RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120841464|UniProtKB=A0ACM8FL13 A0ACM8FL13 LOC120841464 PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 glycosidase#PC00110;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8035077|UniProtKB=A0ACM8E9A8 A0ACM8E9A8 LOC8035077 PTHR10682:SF10 POLY A POLYMERASE POLYNUCLEOTIDE ADENYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC8031338|UniProtKB=A0ACM8FXG1 A0ACM8FXG1 LOC8031338 PTHR20275:SF44 NAD KINASE NAD KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;NADP+ metabolic process#GO:0006739;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172 IXOSC|EnsemblGenome=LOC8023813|UniProtKB=A0ACM8DYX8 A0ACM8DYX8 LOC8023813 PTHR31158:SF10 DUAL OXIDASE 2 LD27791P cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidase#PC00175;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120847459|UniProtKB=A0ACM8FYX4 A0ACM8FYX4 LOC120847459 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8053966|UniProtKB=A0ACM8DUI6 A0ACM8DUI6 LOC8053966 PTHR12153:SF15 SELENOPROTEIN O PROTEIN ADENYLYLTRANSFERASE SELO, MITOCHONDRIAL IXOSC|EnsemblGenome=LOC8053234|UniProtKB=A0ACM8DGW7 A0ACM8DGW7 LOC8053234 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC121838233|UniProtKB=A0ACM8G769 A0ACM8G769 LOC121838233 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8038730|UniProtKB=A0ACM8FJJ4 A0ACM8FJJ4 LOC8038730 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120843714|UniProtKB=A0ACM8EWT0 A0ACM8EWT0 LOC120843714 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120844837|UniProtKB=A0ACM8F0S4 A0ACM8F0S4 PTHR10322:SF23 DNA POLYMERASE CATALYTIC SUBUNIT DNA POLYMERASE DELTA CATALYTIC SUBUNIT catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;DNA-directed DNA polymerase activity#GO:0003887;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;3'-5' exonuclease activity#GO:0008408;transferase activity#GO:0016740;DNA exonuclease activity#GO:0004529;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;exonuclease activity#GO:0004527 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;replisome#GO:0030894;replication fork#GO:0005657;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 IXOSC|EnsemblGenome=LOC8025115|UniProtKB=A0ACM8FRD5 A0ACM8FRD5 LOC8025115 PTHR14950:SF82 DICER-RELATED ENDORIBONUCLEASE DICER nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;RNA binding#GO:0003723;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;binding#GO:0005488;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 programmed cell death#GO:0012501;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell death#GO:0008219;pre-miRNA processing#GO:0031054;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;DNA catabolic process#GO:0006308;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;siRNA processing#GO:0030422;apoptotic process#GO:0006915;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;apoptotic DNA fragmentation#GO:0006309 endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8027209|UniProtKB=A0ACM8DIT9 A0ACM8DIT9 LOC8027209 PTHR13799:SF13 NGG1 INTERACTING FACTOR 3 NIF3-LIKE PROTEIN 1 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8029643|UniProtKB=A0ACM8ED30 A0ACM8ED30 Gdi PTHR11787:SF8 RAB GDP-DISSOCIATION INHIBITOR RAB GDP DISSOCIATION INHIBITOR GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115319833|UniProtKB=A0ACM8EMZ6 A0ACM8EMZ6 LOC115319833 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8036240|UniProtKB=A0ACM8EIA1 A0ACM8EIA1 LOC8036240 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115311560|UniProtKB=A0ACM8EIX4 A0ACM8EIX4 LOC115311560 PTHR18934:SF274 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT DNA_RNA HELICASE DHX36 ATP-dependent activity, acting on DNA#GO:0008094;binding#GO:0005488;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;DNA helicase activity#GO:0003678;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;DNA binding#GO:0003677;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115332174|UniProtKB=A0ACM8EYP3 A0ACM8EYP3 LOC115332174 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8027533|UniProtKB=A0ACM8DXF8 A0ACM8DXF8 LOC8027533 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC115331767|UniProtKB=A0ACM8ENW1 A0ACM8ENW1 LOC115331767 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8031730|UniProtKB=A0ACM8DIM9 A0ACM8DIM9 LOC8031730 PTHR24364:SF18 LP06937P LP06937P membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120835960|UniProtKB=A0ACM8F8X1 A0ACM8F8X1 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121837846|UniProtKB=A0ACM8G5D5 A0ACM8G5D5 LOC121837846 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8029979|UniProtKB=A0ACM8F9B7 A0ACM8F9B7 LOC8029979 PTHR14927:SF0 NUCLEOLAR PROTEIN 10 NUCLEOLAR PROTEIN 10 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC120850130|UniProtKB=A0ACM8G718 A0ACM8G718 LOC120850130 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319540|UniProtKB=A0ACM8FKH4 A0ACM8FKH4 LOC115319540 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115322468|UniProtKB=A0ACM8ERQ1 A0ACM8ERQ1 LOC115322468 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC121837826|UniProtKB=A0ACM8G4Z4 A0ACM8G4Z4 LOC121837826 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115317860|UniProtKB=A0ACM8EK89 A0ACM8EK89 LOC115317860 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;ornithine decarboxylase activity#GO:0004586;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC115321689|UniProtKB=A0ACM8F9P1 A0ACM8F9P1 LOC115321689 PTHR45689:SF5 I[[H]] CHANNEL, ISOFORM E I[[H]] CHANNEL, ISOFORM E voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234 voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC120841989|UniProtKB=A0ACM8FNA3 A0ACM8FNA3 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8037195|UniProtKB=A0ACM8DK24 A0ACM8DK24 LOC8037195 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120846985|UniProtKB=A0ACM8F4K5 A0ACM8F4K5 LOC120846985 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120844890|UniProtKB=A0ACM8F0Y4 A0ACM8F0Y4 LOC120844890 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8028443|UniProtKB=A0ACM8DGG5 A0ACM8DGG5 LOC8028443 PTHR22891:SF111 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;binding#GO:0005488;nucleic acid binding#GO:0003676;nuclease activity#GO:0004518;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8028048|UniProtKB=A0ACM8EJZ8 A0ACM8EJZ8 DNAlig1 PTHR45674:SF15 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 1 ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;DNA metabolic process#GO:0006259;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated DNA replication#GO:0006261;cell cycle process#GO:0022402;DNA replication#GO:0006260;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA strand elongation involved in DNA replication#GO:0006271;mitotic cell cycle#GO:0000278 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA ligase#PC00012 IXOSC|EnsemblGenome=LOC8036133|UniProtKB=A0ACM8E2E5 A0ACM8E2E5 LOC8036133 PTHR13333:SF5 M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL M-AAA PROTEASE-INTERACTING PROTEIN 1, MITOCHONDRIAL establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115316236|UniProtKB=A0ACM8G108 A0ACM8G108 LOC115316236 PTHR24372:SF77 GLYCOPROTEIN HORMONE RECEPTOR LEUCINE-RICH REPEAT-CONTAINING G PROTEIN-COUPLED RECEPTOR 4, ISOFORM C signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121047170|UniProtKB=A0ACM8G191 A0ACM8G191 LOC121047170 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330279|UniProtKB=A0ACM8EMN7 A0ACM8EMN7 LOC115330279 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843914|UniProtKB=A0ACM8EX49 A0ACM8EX49 LOC120843914 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8041873|UniProtKB=A0ACM8DKT3 A0ACM8DKT3 fand PTHR11246:SF5 PRE-MRNA SPLICING FACTOR PRE-MRNA-SPLICING FACTOR SYF1 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8029391|UniProtKB=A0ACM8DI16 A0ACM8DI16 LOC8029391 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 IXOSC|EnsemblGenome=LOC8038072|UniProtKB=A0ACM8DWZ1 A0ACM8DWZ1 LOC8038072 PTHR24333:SF13 HOMEO BOX HB9 LIKE A-RELATED HOMEOBOX DOMAIN-CONTAINING PROTEIN homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8024031|UniProtKB=A0ACM8E6G8 A0ACM8E6G8 Sf3b6 PTHR48526:SF2 SPLICING FACTOR 3B SUBUNIT 6 SPLICING FACTOR 3B SUBUNIT 6 IXOSC|EnsemblGenome=LOC8042664|UniProtKB=A0ACM8DVP8 A0ACM8DVP8 LOC8042664 PTHR18887:SF5 GOLGI-ASSOCIATED PROTEIN GCP360-RELATED GOLGIN SUBFAMILY B MEMBER 1-LIKE IXOSC|EnsemblGenome=LOC115323403|UniProtKB=A0ACM8E2Z2 A0ACM8E2Z2 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311852|UniProtKB=A0ACM8G7Q4 A0ACM8G7Q4 LOC115311852 PTHR38563:SF1 FL(2)D-ASSOCIATED COMPLEX COMPONENT FL(2)D-ASSOCIATED COMPLEX COMPONENT IXOSC|EnsemblGenome=LOC120836294|UniProtKB=A0ACM8EI05 A0ACM8EI05 LOC120836294 PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;organelle organization#GO:0006996;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120844160|UniProtKB=A0ACM8EZ31 A0ACM8EZ31 LOC120844160 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120846003|UniProtKB=A0ACM8F255 A0ACM8F255 LOC120846003 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034944|UniProtKB=A0ACM8E459 A0ACM8E459 LOC8034944 PTHR28589:SF1 28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120843797|UniProtKB=A0ACM8EWZ2 A0ACM8EWZ2 LOC120843797 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8035556|UniProtKB=A0ACM8EQ69 A0ACM8EQ69 Rpn1 PTHR10943:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nucleus#GO:0005634;proteasome complex#GO:0000502;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC115320013|UniProtKB=A0ACM8EQJ5 A0ACM8EQJ5 LOC115320013 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120839084|UniProtKB=A0ACM8EMB1 A0ACM8EMB1 LOC120839084 PTHR13109:SF8 NEUROCHONDRIN NEUROCHONDRIN neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of synaptic plasticity#GO:0048167;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of neuronal synaptic plasticity#GO:0048168;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;multicellular organismal process#GO:0032501;regulation of signaling#GO:0023051;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cell communication#GO:0010646;cell development#GO:0048468;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell projection organization#GO:0030030 neuron projection#GO:0043005;dendritic tree#GO:0097447;dendrite#GO:0030425;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120844152|UniProtKB=A0ACM8EZ10 A0ACM8EZ10 LOC120844152 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8040607|UniProtKB=A0ACM8FSB8 A0ACM8FSB8 LOC8040607 PTHR31077:SF1 U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8052597|UniProtKB=A0ACM8FYC8 A0ACM8FYC8 LOC8052597 PTHR22600:SF59 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE A hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;glycosaminoglycan metabolic process#GO:0030203;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;extracellular region#GO:0005576;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;lysosome#GO:0005764;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8032302|UniProtKB=A0ACM8E1F0 A0ACM8E1F0 LOC8032302 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115310902|UniProtKB=A0ACM8DQE3 A0ACM8DQE3 LOC115310902 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120839312|UniProtKB=A0ACM8FE32 A0ACM8FE32 LOC120839312 PTHR24381:SF486 ZINC FINGER PROTEIN ADULT ENHANCER FACTOR 1-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8037733|UniProtKB=A0ACM8DMF3 A0ACM8DMF3 LOC8037733 PTHR11960:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E1-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8028451|UniProtKB=A0ACM8DTJ0 A0ACM8DTJ0 LOC8028451 PTHR13285:SF26 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE RASP acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115328925|UniProtKB=A0ACM8E9B8 A0ACM8E9B8 LOC115328925 PTHR44229:SF4 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] CHAIN DEHYDROGENASE_REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02990)-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121833252|UniProtKB=A0ACM8F3N1 A0ACM8F3N1 LOC8029503 PTHR24058:SF135 DUAL SPECIFICITY PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120837868|UniProtKB=A0ACM8EJG4 A0ACM8EJG4 LOC120837868 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8032453|UniProtKB=A0ACM8EET7 A0ACM8EET7 Ndc1 PTHR13269:SF6 NUCLEOPORIN NDC1 NUCLEOPORIN NDC1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nuclear pore organization#GO:0006999;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115330718|UniProtKB=A0ACM8EB64 A0ACM8EB64 CSN4 PTHR10855:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 COP9 SIGNALOSOME COMPLEX SUBUNIT 4 nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protease#PC00190 IXOSC|EnsemblGenome=LOC8029917|UniProtKB=A0ACM8E0M1 A0ACM8E0M1 LOC8029917 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8027994|UniProtKB=A0ACM8DTF2 A0ACM8DTF2 LOC8027994 PTHR23248:SF9 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid translocation#GO:0045332;endomembrane system organization#GO:0010256;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid transport#GO:0006869 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8053104|UniProtKB=A0ACM8E1P6 A0ACM8E1P6 LOC8053104 PTHR24264:SF87 TRYPSIN-RELATED SERINE PROTEASE 30 ISOFORM X1 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115318512|UniProtKB=A0ACM8FCL2 A0ACM8FCL2 LOC115318512 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589 IXOSC|EnsemblGenome=LOC8027600|UniProtKB=A0ACM8E438 A0ACM8E438 LOC8027600 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8052938|UniProtKB=A0ACM8DW21 A0ACM8DW21 LOC8052938 PTHR17920:SF3 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 IXOSC|EnsemblGenome=LOC8041943|UniProtKB=A0ACM8E2K1 A0ACM8E2K1 LOC8041943 PTHR43782:SF5 ARGINASE ARGINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;cation binding#GO:0043169;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8025721|UniProtKB=A0ACM8G0T0 A0ACM8G0T0 LOC8025721 PTHR13493:SF3 ZINC FINGER CCHC DOMAIN-CONTAINING RRNA N(6)-ADENOSINE-METHYLTRANSFERASE ZCCHC4 catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC120839224|UniProtKB=A0ACM8FWP1 A0ACM8FWP1 LOC120839224 PTHR14469:SF0 SARCOMA ANTIGEN NY-SAR-23 FAMILY WITH SEQUENCE SIMILARITY 113 IXOSC|EnsemblGenome=LOC8031221|UniProtKB=A0ACM8DUM9 A0ACM8DUM9 LOC8031221 PTHR10127:SF793 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120839288|UniProtKB=A0ACM8ELK2 A0ACM8ELK2 LOC120839288 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8029937|UniProtKB=A0ACM8DJ45 A0ACM8DJ45 LOC8029937 PTHR21393:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S27 SMALL RIBOSOMAL SUBUNIT PROTEIN MS27 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8035530|UniProtKB=A0ACM8DGL4 A0ACM8DGL4 LOC8035530 PTHR15858:SF7 IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 IMMEDIATE EARLY RESPONSE 3-INTERACTING PROTEIN 1 regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;regulation of establishment of protein localization#GO:0070201;cellular localization#GO:0051641;regulation of secretion#GO:0051046;localization#GO:0051179;positive regulation of cellular component organization#GO:0051130;positive regulation of secretion#GO:0051047;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of secretion by cell#GO:1903532;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;establishment of localization in cell#GO:0051649;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of protein secretion#GO:0050714;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 IXOSC|EnsemblGenome=LOC120848992|UniProtKB=A0ACM8FY74 A0ACM8FY74 LOC120848992 PTHR13559:SF1 INTRACELLULAR TRAFFIC PROTEIN-RELATED PROTEIN FUZZY HOMOLOG cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515 IXOSC|EnsemblGenome=LOC8023108|UniProtKB=A0ACM8DGE7 A0ACM8DGE7 P5CDh1 PTHR42862:SF1 DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE 1, ISOFORM A-RELATED DELTA-1-PYRROLINE-5-CARBOXYLATE DEHYDROGENASE, MITOCHONDRIAL-RELATED aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552;mitochondrion#GO:0005739;cytoplasmic side of plasma membrane#GO:0009898;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC8053575|UniProtKB=A0ACM8FP19 A0ACM8FP19 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8038668|UniProtKB=A0ACM8FN97 A0ACM8FN97 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987 aspartic protease#PC00053;protease#PC00190 IXOSC|EnsemblGenome=LOC8037123|UniProtKB=A0ACM8DHX3 A0ACM8DHX3 nclb PTHR14091:SF0 PERIODIC TRYPTOPHAN PROTEIN 1 PERIODIC TRYPTOPHAN PROTEIN 1 HOMOLOG DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;chromatin DNA binding#GO:0031490 regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase I#GO:0045943;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120845340|UniProtKB=A0ACM8F0M3 A0ACM8F0M3 LOC120845340 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8052006|UniProtKB=A0ACM8DYP9 A0ACM8DYP9 LOC8052006 PTHR22589:SF67 CARNITINE O-ACYLTRANSFERASE PEROXISOMAL CARNITINE O-OCTANOYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8042022|UniProtKB=A0ACM8F4V9 A0ACM8F4V9 HDAC4 PTHR45364:SF15 HISTONE DEACETYLASE 9-RELATED HISTONE DEACETYLASE protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8032073|UniProtKB=A0ACM8E1C2 A0ACM8E1C2 Sec71 PTHR10663:SF415 GUANYL-NUCLEOTIDE EXCHANGE FACTOR LD29171P Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC120846331|UniProtKB=A0ACM8F227 A0ACM8F227 LOC120846331 PTHR21324:SF2 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED CWH43-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115330760|UniProtKB=A0ACM8EC88 A0ACM8EC88 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8033508|UniProtKB=A0ACM8FDK6 A0ACM8FDK6 Cog3 PTHR13302:SF8 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 3 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 3 cargo adaptor activity#GO:0140312;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization in cell#GO:0051649;retrograde transport, vesicle recycling within Golgi#GO:0000301 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;COG complex#GO:0017119 IXOSC|EnsemblGenome=LOC121834715|UniProtKB=A0ACM8FQJ9 A0ACM8FQJ9 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315846|UniProtKB=A0ACM8DVD0 A0ACM8DVD0 LOC115315846 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8024740|UniProtKB=A0ACM8F7L0 A0ACM8F7L0 LOC8024740 PTHR11827:SF6 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SOLUTE CARRIER FAMILY 12 MEMBER 8 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8030361|UniProtKB=A0ACM8DGV0 A0ACM8DGV0 LOC8030361 PTHR15431:SF19 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 20 cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 IXOSC|EnsemblGenome=LOC8035188|UniProtKB=A0ACM8EIC0 A0ACM8EIC0 NAT1 PTHR23253:SF9 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;translation factor activity#GO:0180051;RNA binding#GO:0003723;translation initiation factor activity#GO:0003743 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8052036|UniProtKB=A0ACM8FJ04 A0ACM8FJ04 LOC8052036 PTHR31226:SF1 TRANSMEMBRANE PROTEIN 117 TRANSMEMBRANE PROTEIN 117 signaling#GO:0023052;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress#GO:0070059;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;apoptotic signaling pathway#GO:0097190 IXOSC|EnsemblGenome=LOC8041980|UniProtKB=A0ACM8EUE4 A0ACM8EUE4 LOC8041980 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115325487|UniProtKB=A0ACM8G3C1 A0ACM8G3C1 LOC115325487 PTHR10361:SF75 SODIUM-BILE ACID COTRANSPORTER SUBFAMILY NOT NAMED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8036496|UniProtKB=A0ACM8DJZ4 A0ACM8DJZ4 LOC8036496 PTHR19384:SF10 NITRIC OXIDE SYNTHASE-RELATED NADPH-DEPENDENT DIFLAVIN OXIDOREDUCTASE 1 heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824;ribonucleotide binding#GO:0032553;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120842162|UniProtKB=A0ACM8ET73 A0ACM8ET73 Pgm1 PTHR22573:SF2 PHOSPHOHEXOMUTASE FAMILY MEMBER PHOSPHOGLUCOMUTASE 1 isomerase activity#GO:0016853;intramolecular phosphotransferase activity#GO:0016868;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 carbohydrate metabolic process#GO:0005975;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 isomerase#PC00135;metabolite interconversion enzyme#PC00262;mutase#PC00160 IXOSC|EnsemblGenome=LOC8024630|UniProtKB=A0ACM8FRX5 A0ACM8FRX5 hop PTHR45807:SF7 TYROSINE-PROTEIN KINASE HOPSCOTCH TYROSINE-PROTEIN KINASE HOPSCOTCH non-receptor tyrosine protein kinase#PC00168 IXOSC|EnsemblGenome=LOC8038536|UniProtKB=A0ACM8E815 A0ACM8E815 PTHR16099:SF5 8-OXO-DGTP DIPHOSPHATES NUDT15 NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15 IXOSC|EnsemblGenome=LOC115325471|UniProtKB=A0ACM8E685 A0ACM8E685 LOC115325471 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327459|UniProtKB=A0ACM8EGQ9 A0ACM8EGQ9 LOC115327459 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;cellular process#GO:0009987;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8038739|UniProtKB=A0ACM8DP50 A0ACM8DP50 LOC8038739 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120838283|UniProtKB=A0ACM8FYA2 A0ACM8FYA2 LOC120838283 PTHR12461:SF104 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 5 binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8027145|UniProtKB=A0ACM8E4W7 A0ACM8E4W7 LOC8027145 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115311041|UniProtKB=A0ACM8EU60 A0ACM8EU60 LOC115311041 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120845331|UniProtKB=A0ACM8F0I9 A0ACM8F0I9 LOC120845331 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115319179|UniProtKB=A0ACM8DYQ6 A0ACM8DYQ6 LOC115319179 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8032075|UniProtKB=A0ACM8E6W7 A0ACM8E6W7 CSN5 PTHR10410:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 5 metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726 nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 translation initiation factor#PC00224;translation factor#PC00223 PDGF signaling pathway#P00047>c-Jun#P01163 IXOSC|EnsemblGenome=LOC8029015|UniProtKB=A0ACM8EVX8 A0ACM8EVX8 LOC8029015 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115328491|UniProtKB=A0ACM8E8R0 A0ACM8E8R0 LOC115328491 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194 biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 IXOSC|EnsemblGenome=LOC120846118|UniProtKB=A0ACM8F1C7 A0ACM8F1C7 LOC120846118 PTHR13659:SF5 AUTOSOMAL HIGHLY CONSERVED PROTEIN PROTEIN FAM8A1 IXOSC|EnsemblGenome=LOC120837229|UniProtKB=A0ACM8EHW1 A0ACM8EHW1 LOC120837229 PTHR11426:SF274 HISTONE H3 HISTONE H3-7 mitotic cell cycle process#GO:1903047;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;kinetochore organization#GO:0051383;localization#GO:0051179;organelle fission#GO:0048285;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;nuclear division#GO:0000280;organelle localization#GO:0051640;mitotic cell cycle#GO:0000278;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121836567|UniProtKB=A0ACM8FZ86 A0ACM8FZ86 LOC121836567 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120840971|UniProtKB=A0ACM8FEX4 A0ACM8FEX4 LOC120840971 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8034808|UniProtKB=A0ACM8EMB0 A0ACM8EMB0 LOC8034808 PTHR14557:SF5 PROTEIN C7ORF21 UBIQUITIN-LIKE DOMAIN-CONTAINING PROTEIN cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170 IXOSC|EnsemblGenome=LOC120837787|UniProtKB=A0ACM8G2Z7 A0ACM8G2Z7 LOC120837787 PTHR10730:SF56 PROCOLLAGEN-LYSINE,2-OXOGLUTARATE 5-DIOXYGENASE/GLYCOSYLTRANSFERASE 25 FAMILY MEMBER GLYCOSYLTRANSFERASE 25 FAMILY MEMBER glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8028658|UniProtKB=A0ACM8DH04 A0ACM8DH04 LOC8028658 PTHR46956:SF2 NUCLEOSIDE DIPHOSPHATE KINASE 6 NUCLEOSIDE DIPHOSPHATE KINASE 6-LIKE kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120839907|UniProtKB=A0ACM8ENY1 A0ACM8ENY1 LOC120839907 PTHR12944:SF2 SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE tRNA binding#GO:0000049;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 protein metabolic process#GO:0019538;translation#GO:0006412;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein biosynthetic process#GO:0160307;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;translational elongation#GO:0006414;post-transcriptional regulation of gene expression#GO:0010608;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222 IXOSC|EnsemblGenome=LOC8023240|UniProtKB=A0ACM8DGK9 A0ACM8DGK9 LOC8023240 PTHR19316:SF18 PROTEIN FOLDING REGULATOR HSP70-BINDING PROTEIN 1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120841660|UniProtKB=A0ACM8FDY1 A0ACM8FDY1 LOC120841660 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8035432|UniProtKB=A0ACM8E2C2 A0ACM8E2C2 PTHR13152:SF0 TFIIH, POLYPEPTIDE 4 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 4 RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIH complex#P00664;Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392 IXOSC|EnsemblGenome=LOC8036132|UniProtKB=A0ACM8FSK5 A0ACM8FSK5 ssp3 PTHR31434:SF2 S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM S PHASE CYCLIN A-ASSOCIATED PROTEIN IN THE ENDOPLASMIC RETICULUM IXOSC|EnsemblGenome=LOC8038546|UniProtKB=A0ACM8EFZ5 A0ACM8EFZ5 PTHR19308:SF8 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN STAR-RELATED LIPID TRANSFER PROTEIN 7, MITOCHONDRIAL IXOSC|EnsemblGenome=LOC8053418|UniProtKB=A0ACM8E3F0 A0ACM8E3F0 unc-45 PTHR45994:SF1 FI21225P1 FI21225P1 protein binding#GO:0005515;Hsp90 protein binding#GO:0051879;heat shock protein binding#GO:0031072;binding#GO:0005488 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120850502|UniProtKB=A0ACM8FAY6 A0ACM8FAY6 LOC120850502 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8037052|UniProtKB=A0ACM8DPW1 A0ACM8DPW1 sel PTHR13341:SF2 MIR-INTERACTING SAPOSIN-LIKE PROTEIN PROTEIN SEELE molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121835261|UniProtKB=A0ACM8FTK5 A0ACM8FTK5 LOC121835261 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026915|UniProtKB=A0ACM8DII5 A0ACM8DII5 LOC8026915 PTHR28652:SF2 TRANSMEMBRANE PROTEIN 59-LIKE PROTEIN MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2 IXOSC|EnsemblGenome=LOC121837162|UniProtKB=A0ACM8G3U7 A0ACM8G3U7 LOC121837162 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;ornithine decarboxylase activity#GO:0004586 polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC115330158|UniProtKB=A0ACM8F2Z2 A0ACM8F2Z2 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115323148|UniProtKB=A0ACM8G5L2 A0ACM8G5L2 LOC115323148 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120836726|UniProtKB=A0ACM8EFA1 A0ACM8EFA1 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837235|UniProtKB=A0ACM8EGY2 A0ACM8EGY2 LOC120837235 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8033463|UniProtKB=A0ACM8DQR8 A0ACM8DQR8 LOC8033463 PTHR31581:SF2 KICSTOR COMPLEX PROTEIN C12ORF66 KICSTOR SUBUNIT 2 IXOSC|EnsemblGenome=LOC8024838|UniProtKB=A0ACM8DIR2 A0ACM8DIR2 LOC8024838 PTHR44086:SF15 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED THIOSULFATE SULFURTRANSFERASE_RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 3 sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 IXOSC|EnsemblGenome=LOC120842123|UniProtKB=A0ACM8ESV5 A0ACM8ESV5 LOC120842123 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031076|UniProtKB=A0ACM8FMK5 A0ACM8FMK5 l(3)mbt PTHR12247:SF141 POLYCOMB GROUP PROTEIN LD05287P chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8024054|UniProtKB=A0ACM8FVG5 A0ACM8FVG5 LOC8024054 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8043867|UniProtKB=A0ACM8DL34 A0ACM8DL34 LOC8043867 PTHR10270:SF323 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14-RELATED DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;central nervous system development#GO:0007417;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8053563|UniProtKB=A0ACM8E8E4 A0ACM8E8E4 TfIIEalpha PTHR13097:SF7 TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEalpha#P00669;Transcription regulation by bZIP transcription factor#P00055>TFIIEalpha#P01398;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395 IXOSC|EnsemblGenome=LOC8036441|UniProtKB=A0ACM8DZN6 A0ACM8DZN6 Cbp80 PTHR12412:SF2 CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8037682|UniProtKB=A0ACM8E455 A0ACM8E455 LOC8037682 PTHR43782:SF5 ARGINASE ARGINASE hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034045|UniProtKB=A0ACM8DIS3 A0ACM8DIS3 RpIII128 PTHR20856:SF8 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC2 catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA transcription#GO:0009301;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC8027428|UniProtKB=A0ACM8DV34 A0ACM8DV34 LOC8027428 PTHR45630:SF23 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE polyamine transmembrane transporter activity#GO:0015203;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nitrogen compound transport#GO:0071705;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120843061|UniProtKB=A0ACM8E9M8 A0ACM8E9M8 LOC120843061 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8035742|UniProtKB=A0ACM8EKC4 A0ACM8EKC4 LOC8035742 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8024637|UniProtKB=A0ACM8E8R2 A0ACM8E8R2 Phax PTHR13135:SF0 CYTOSOLIC RESINIFERATOXIN BINDING PROTEIN RBP-26 PHOSPHORYLATED ADAPTER RNA EXPORT PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;establishment of localization#GO:0051234;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120850257|UniProtKB=A0ACM8FAG4 A0ACM8FAG4 LOC120850257 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029452|UniProtKB=A0ACM8EAJ0 A0ACM8EAJ0 kkv PTHR22914:SF42 CHITIN SYNTHASE CHITIN SYNTHASE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 chitin metabolic process#GO:0006030;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;aminoglycan biosynthetic process#GO:0006023;biosynthetic process#GO:0009058;amino sugar metabolic process#GO:0006040 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 transferase#PC00220 IXOSC|EnsemblGenome=LOC120837640|UniProtKB=A0ACM8EHZ2 A0ACM8EHZ2 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8038636|UniProtKB=A0ACM8DUL8 A0ACM8DUL8 Surf6 PTHR14369:SF0 SURFEIT LOCUS PROTEIN 6 SURFEIT LOCUS PROTEIN 6 RNA binding#GO:0003723;molecular condensate scaffold activity#GO:0140693;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;cellular process#GO:0009987 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8024701|UniProtKB=A0ACM8EM93 A0ACM8EM93 LOC8024701 PTHR24388:SF116 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115317457|UniProtKB=A0ACM8FAQ7 A0ACM8FAQ7 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8029880|UniProtKB=A0ACM8EPQ4 A0ACM8EPQ4 LOC8029880 PTHR46345:SF8 INVERTED FORMIN-2 INVERTED FORMIN-2 IXOSC|EnsemblGenome=LOC121836468|UniProtKB=A0ACM8FZQ2 A0ACM8FZQ2 LOC121836468 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835271|UniProtKB=A0ACM8FT41 A0ACM8FT41 LOC121835271 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115322207|UniProtKB=A0ACM8E2N8 A0ACM8E2N8 Rassf PTHR22738:SF15 RASSF LD40758P cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121835613|UniProtKB=A0ACM8FV33 A0ACM8FV33 LOC121835613 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120841512|UniProtKB=A0ACM8EST6 A0ACM8EST6 LOC120841512 PTHR10454:SF253 CASPASE CASPASE DRICE-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;programmed cell death#GO:0012501;regulation of neuron apoptotic process#GO:0043523;regulation of programmed cell death#GO:0043067;apoptotic process#GO:0006915;cell death#GO:0008219;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121833030|UniProtKB=A0ACM8FHX2 A0ACM8FHX2 LOC121833030 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8033670|UniProtKB=A0ACM8DVH7 A0ACM8DVH7 CDC50 PTHR10926:SF0 CELL CYCLE CONTROL PROTEIN 50 CELL DIVISION CYCLE 50, ISOFORM A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid transport#GO:0015914 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 IXOSC|EnsemblGenome=LOC115314917|UniProtKB=A0ACM8DUM1 A0ACM8DUM1 LOC115314917 PTHR43195:SF1 TRANSKETOLASE TRANSKETOLASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transketolase or transaldolase activity#GO:0016744;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;transketolase activity#GO:0004802;cation binding#GO:0043169 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transketolase#PC00221;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040182|UniProtKB=A0ACM8E523 A0ACM8E523 LOC8040182 PTHR45787:SF1 LD11652P BEADEX, ISOFORM D transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121837779|UniProtKB=A0ACM8G4R7 A0ACM8G4R7 LOC121837779 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8039732|UniProtKB=A0ACM8E1T6 A0ACM8E1T6 SPARC PTHR13866:SF14 SPARC OSTEONECTIN BM-40 cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 extracellular matrix glycoprotein#PC00100;extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8054049|UniProtKB=A0ACM8DX77 A0ACM8DX77 Med PTHR13703:SF45 SMAD SMAD FAMILY MEMBER 4 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;response to BMP#GO:0071772;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;intracellular signaling cassette#GO:0141124;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to growth factor stimulus#GO:0071363;signaling#GO:0023052;cell differentiation#GO:0030154;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 SCW signaling pathway#P06216>MED#P06323;GBB signaling pathway#P06214>MED#P06299;TGF-beta signaling pathway#P00052>Co-Smads#P01276;DPP-SCW signaling pathway#P06212>MED#P06265;DPP signaling pathway#P06213>MED#P06279;MYO signaling pathway#P06215>MED#P06311;Activin beta signaling pathway#P06210>MED#P06233;TGF-beta signaling pathway#P00052>RSmads#P01292;BMP/activin signaling pathway-drosophila#P06211>Co-Smad#P06254;ALP23B signaling pathway#P06209>MED#P06221 IXOSC|EnsemblGenome=LOC8042589|UniProtKB=A0ACM8DKX9 A0ACM8DKX9 LOC8042589 PTHR43675:SF1 ARSENITE METHYLTRANSFERASE RIKEN CDNA 2700097O09 GENE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120849061|UniProtKB=A0ACM8F6W1 A0ACM8F6W1 PTHR46896:SF3 SENTRIN-SPECIFIC PROTEASE FI06413P-RELATED cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC120837056|UniProtKB=A0ACM8FWR5 A0ACM8FWR5 LOC120837056 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120849290|UniProtKB=A0ACM8F7H7 A0ACM8F7H7 LOC120849290 PTHR21355:SF0 G-PROTEIN COUPLED RECEPTOR-ASSOCIATED PROTEIN LMBRD2 LMBR1 DOMAIN-CONTAINING PROTEIN 2 HOMOLOG membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8040028|UniProtKB=A0ACM8DKF3 A0ACM8DKF3 PTHR13276:SF0 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 GUANINE NUCLEOTIDE EXCHANGE FACTOR MSS4 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;post-Golgi vesicle-mediated transport#GO:0006892 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115316956|UniProtKB=A0ACM8F4K2 A0ACM8F4K2 LOC115316956 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115329674|UniProtKB=A0ACM8E9Y0 A0ACM8E9Y0 LOC115329674 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115332799|UniProtKB=A0ACM8F8U8 A0ACM8F8U8 LOC115332799 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115330700|UniProtKB=A0ACM8FAQ5 A0ACM8FAQ5 LOC115330700 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043839|UniProtKB=A0ACM8DTJ6 A0ACM8DTJ6 LOC8043839 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841471|UniProtKB=A0ACM8ERS8 A0ACM8ERS8 fws PTHR13228:SF3 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 5 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 5 intra-Golgi vesicle-mediated transport#GO:0006891;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COG complex#GO:0017119;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8052962|UniProtKB=A0ACM8EF90 A0ACM8EF90 LOC8052962 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831 polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC115317900|UniProtKB=A0ACM8F834 A0ACM8F834 LOC115317900 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 IXOSC|EnsemblGenome=LOC8037463|UniProtKB=A0ACM8FS03 A0ACM8FS03 LOC8037463 PTHR24039:SF54 FIBRILLIN-RELATED FIBRILLIN-2-LIKE ISOFORM X4 extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8053885|UniProtKB=A0ACM8FYP9 A0ACM8FYP9 Camta PTHR23335:SF1 CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR CAMTA CALMODULIN-BINDING TRANSCRIPTION ACTIVATOR, ISOFORM F nucleic acid binding#GO:0003676;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120842828|UniProtKB=A0ACM8EVS9 A0ACM8EVS9 LOC120842828 PTHR24373:SF406 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TARTAN, ISOFORM B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121838250|UniProtKB=A0ACM8G797 A0ACM8G797 LOC121838250 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8041768|UniProtKB=A0ACM8DNI3 A0ACM8DNI3 LOC8041768 PTHR12277:SF194 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN FI04476P hydrolase activity#GO:0016787;lipase activity#GO:0016298;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;phospholipase activity#GO:0120569 glycerophospholipid metabolic process#GO:0006650;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042;glycerophospholipid catabolic process#GO:0046475;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 serine protease#PC00203 IXOSC|EnsemblGenome=LOC121837764|UniProtKB=A0ACM8G526 A0ACM8G526 LOC121837764 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115322300|UniProtKB=A0ACM8E1Z3 A0ACM8E1Z3 LOC115322300 PTHR46212:SF3 PEFLIN PROGRAMMED CELL DEATH PROTEIN 6 IXOSC|EnsemblGenome=LOC121837976|UniProtKB=A0ACM8G7D2 A0ACM8G7D2 LOC121837976 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8029638|UniProtKB=A0ACM8EC52 A0ACM8EC52 LOC8029638 PTHR15454:SF35 NISCHARIN RELATED NISCHARIN Rac protein signal transduction#GO:0016601;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8050669|UniProtKB=A0ACM8EDJ4 A0ACM8EDJ4 LOC8050669 PTHR12155:SF41 SCHLAFEN SCHLAFEN ALBA-2 DOMAIN-CONTAINING PROTEIN endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC8040054|UniProtKB=A0ACM8EQZ8 A0ACM8EQZ8 LOC8040054 PTHR46221:SF3 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FERM AND PDZ DOMAIN-CONTAINING PROTEIN 4 IXOSC|EnsemblGenome=LOC8028452|UniProtKB=A0ACM8F748 A0ACM8F748 spel1 PTHR11361:SF35 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER DNA MISMATCH REPAIR PROTEIN SPELLCHECKER 1 double-stranded DNA binding#GO:0003690;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;response to stimulus#GO:0050896;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8028672|UniProtKB=A0ACM8E8H1 A0ACM8E8H1 Mettl3 PTHR12829:SF7 N6-ADENOSINE-METHYLTRANSFERASE N(6)-ADENOSINE-METHYLTRANSFERASE CATALYTIC SUBUNIT METTL3 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;RNA modification#GO:0009451;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA modification#GO:0016556 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC115332249|UniProtKB=A0ACM8EM78 A0ACM8EM78 LOC115332249 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120840411|UniProtKB=A0ACM8ENY4 A0ACM8ENY4 LOC120840411 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030230|UniProtKB=A0ACM8DGI1 A0ACM8DGI1 LOC8030230 PTHR12119:SF2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX UBIQUINONE-BINDING PROTEIN QP-C CYTOCHROME B-C1 COMPLEX SUBUNIT 8 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900 catalytic complex#GO:1902494;respiratory chain complex III#GO:0045275;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8040915|UniProtKB=A0ACM8E0Q7 A0ACM8E0Q7 LOC8040915 PTHR13832:SF354 PROTEIN PHOSPHATASE 2C GM14138P phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8027128|UniProtKB=A0ACM8F800 A0ACM8F800 LOC8027128 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8037131|UniProtKB=A0ACM8DHX1 A0ACM8DHX1 RanBPM PTHR12864:SF49 RAN BINDING PROTEIN 9-RELATED RAN-BINDING PROTEINS 9_10 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;organelle organization#GO:0006996;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056 catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8029666|UniProtKB=A0ACM8DVY8 A0ACM8DVY8 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219 protease#PC00190;aspartic protease#PC00053 IXOSC|EnsemblGenome=LOC8038936|UniProtKB=A0ACM8DK92 A0ACM8DK92 LOC8038936 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120837025|UniProtKB=A0ACM8EGB8 A0ACM8EGB8 LOC120837025 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8033953|UniProtKB=A0ACM8DIM1 A0ACM8DIM1 LOC8033953 PTHR13445:SF3 TUMOR SUPPRESSING SUBTRANSFERABLE CANDIDATE 4 TSSC4 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN TSSC4 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120838584|UniProtKB=A0ACM8EK42 A0ACM8EK42 LOC120838584 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8053570|UniProtKB=A0ACM8DLA8 A0ACM8DLA8 Ccdc58 PTHR31905:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 58 PROTEIN MIX23 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115310542|UniProtKB=A0ACM8DQ16 A0ACM8DQ16 PTHR12066:SF0 TELOMERASE REVERSE TRANSCRIPTASE TELOMERASE REVERSE TRANSCRIPTASE DNA polymerase activity#GO:0034061;telomerase activity#GO:0003720;catalytic activity, acting on DNA#GO:0140097;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;RNA-directed DNA polymerase activity#GO:0003964;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;telomere organization#GO:0032200;nucleic acid biosynthetic process#GO:0141187;telomere maintenance via telomerase#GO:0007004;telomere maintenance via telomere lengthening#GO:0010833;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;RNA-templated DNA biosynthetic process#GO:0006278;metabolic process#GO:0008152 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115322675|UniProtKB=A0ACM8EWT7 A0ACM8EWT7 LOC115322675 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849309|UniProtKB=A0ACM8FL86 A0ACM8FL86 LOC120849309 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121046738|UniProtKB=A0ACM8FDF5 A0ACM8FDF5 LOC121046738 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115327416|UniProtKB=A0ACM8FZ01 A0ACM8FZ01 LOC115327416 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121834784|UniProtKB=A0ACM8FPY8 A0ACM8FPY8 LOC121834784 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052831|UniProtKB=A0ACM8EIU6 A0ACM8EIU6 LOC8052831 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8037517|UniProtKB=A0ACM8DX81 A0ACM8DX81 LOC8037517 PTHR38926:SF87 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6 protein-containing complex binding#GO:0044877;binding#GO:0005488 IXOSC|EnsemblGenome=LOC8026636|UniProtKB=A0ACM8E0V3 A0ACM8E0V3 PTHR45653:SF13 DEDICATOR OF CYTOKINESIS MYOBLAST CITY, ISOFORM B binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 myoblast fusion#GO:0007520;muscle cell differentiation#GO:0042692;cellular process#GO:0009987;cell differentiation#GO:0030154;cell migration#GO:0016477;cell motility#GO:0048870;muscle structure development#GO:0061061;cell-cell fusion#GO:0140253;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;syncytium formation by cell-cell fusion#GO:0000768;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;striated muscle cell differentiation#GO:0051146 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 Integrin signalling pathway#P00034>Dock180#P00930 IXOSC|EnsemblGenome=LOC8043065|UniProtKB=A0ACM8E6W8 A0ACM8E6W8 Pdp PTHR13832:SF792 PROTEIN PHOSPHATASE 2C GM14286P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 DPP signaling pathway#P06213>PDP#P06280;BMP/activin signaling pathway-drosophila#P06211>PDP#P06248;SCW signaling pathway#P06216>PDP#P06324;GBB signaling pathway#P06214>PDP#P06297;DPP-SCW signaling pathway#P06212>PDP#P06262 IXOSC|EnsemblGenome=LOC115313765|UniProtKB=A0ACM8F7I2 A0ACM8F7I2 LOC115322880 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041626|UniProtKB=A0ACM8DKR2 A0ACM8DKR2 LOC8041626 PTHR11232:SF74 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PID DOMAIN-CONTAINING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8024967|UniProtKB=A0ACM8FC78 A0ACM8FC78 LOC8024967 PTHR12231:SF256 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN NEUROGLIAN immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115311561|UniProtKB=A0ACM8DR52 A0ACM8DR52 LOC115311561 PTHR24150:SF8 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND MYND DOMAIN-CONTAINING PROTEIN 2 IXOSC|EnsemblGenome=LOC115324964|UniProtKB=A0ACM8E4I1 A0ACM8E4I1 LOC115324964 PTHR46229:SF2 BOLA TRANSCRIPTION REGULATOR BOLA-LIKE PROTEIN 1 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115309001|UniProtKB=A0ACM8DN61 A0ACM8DN61 PTHR22763:SF163 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF139 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120850515|UniProtKB=A0ACM8FB10 A0ACM8FB10 LOC120850515 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=ISCI023049|UniProtKB=B7QKS1 B7QKS1 ISCW023049 PTHR19920:SF0 WD40 PROTEIN CIAO1 CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115321744|UniProtKB=A0ACM8FEX0 A0ACM8FEX0 LOC115321744 PTHR14024:SF49 PERILIPIN LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 1 lipid storage#GO:0019915;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120843800|UniProtKB=A0ACM8EWM3 A0ACM8EWM3 LOC120843800 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115322410|UniProtKB=A0ACM8F7T0 A0ACM8F7T0 LOC115322410 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC121832995|UniProtKB=A0ACM8G0D0 A0ACM8G0D0 LOC121832995 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052885|UniProtKB=A0ACM8G7Q5 A0ACM8G7Q5 LOC8052885 PTHR24256:SF579 TRYPTASE-RELATED WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8035324|UniProtKB=A0ACM8DXH6 A0ACM8DXH6 LOC8035324 PTHR23322:SF6 FAS-ASSOCIATED PROTEIN UBX DOMAIN-CONTAINING PROTEIN 7 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120849499|UniProtKB=A0ACM8F801 A0ACM8F801 LOC120849499 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular process#GO:0009987;heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC121045639|UniProtKB=A0ACM8G4T9 A0ACM8G4T9 LOC121838478 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310232|UniProtKB=A0ACM8EYX1 A0ACM8EYX1 LOC115310232 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120839389|UniProtKB=A0ACM8FKJ9 A0ACM8FKJ9 LOC120839389 PTHR38332:SF3 PROTEIN CBG11604 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115313924|UniProtKB=A0ACM8EIS1 A0ACM8EIS1 LOC115313924 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053959|UniProtKB=A0ACM8DLX4 A0ACM8DLX4 Prosalpha7 PTHR11599:SF10 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-3 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 IXOSC|EnsemblGenome=LOC121045977|UniProtKB=A0ACM8FCK1 A0ACM8FCK1 LOC121045977 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836587|UniProtKB=A0ACM8FYS3 A0ACM8FYS3 LOC121836587 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121835729|UniProtKB=A0ACM8FVI3 A0ACM8FVI3 LOC121835729 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120841877|UniProtKB=A0ACM8ESB3 A0ACM8ESB3 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8031206|UniProtKB=A0ACM8F1A7 A0ACM8F1A7 LOC8031206 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;oxidoreductase complex#GO:1990204;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120848293|UniProtKB=A0ACM8F6G8 A0ACM8F6G8 LOC120848293 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115312030|UniProtKB=A0ACM8DRH4 A0ACM8DRH4 NfI PTHR11492:SF8 NUCLEAR FACTOR I NUCLEAR FACTOR I, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8043269|UniProtKB=A0ACM8E9D5 A0ACM8E9D5 fs(1)M3 PTHR15261:SF4 THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120836309|UniProtKB=A0ACM8ENM8 A0ACM8ENM8 LOC120836309 PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED IXOSC|EnsemblGenome=LOC121835457|UniProtKB=A0ACM8FUU0 A0ACM8FUU0 LOC121835457 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031367|UniProtKB=A0ACM8E7S9 A0ACM8E7S9 LOC8031367 PTHR11412:SF171 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN-LIKE ISOFORM X1 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121834502|UniProtKB=A0ACM8FQ58 A0ACM8FQ58 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121836644|UniProtKB=A0ACM8G0F1 A0ACM8G0F1 LOC121836644 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8030454|UniProtKB=A0ACM8G0S3 A0ACM8G0S3 LOC8030454 PTHR46528:SF1 PROTEIN SON PROTEIN SON nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120844723|UniProtKB=A0ACM8EZH6 A0ACM8EZH6 LOC120844723 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8028398|UniProtKB=A0ACM8FK88 A0ACM8FK88 LOC8028398 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115321415|UniProtKB=A0ACM8E283 A0ACM8E283 PTHR19847:SF7 DDB1- AND CUL4-ASSOCIATED FACTOR 11 DDB1- AND CUL4-ASSOCIATED FACTOR 11 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8023751|UniProtKB=A0ACM8DHI3 A0ACM8DHI3 LOC8023751 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8037108|UniProtKB=A0ACM8FBY2 A0ACM8FBY2 PTHR24388:SF38 ZINC FINGER PROTEIN TRANSCRIPTIONAL REPRESSOR SCRATCH 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8024150|UniProtKB=A0ACM8DI03 A0ACM8DI03 LOC8024150 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121835313|UniProtKB=A0ACM8FT52 A0ACM8FT52 LOC121835313 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8053053|UniProtKB=A0ACM8DPX3 A0ACM8DPX3 Pomp PTHR12828:SF3 PROTEASOME MATURATION PROTEIN UMP1 PROTEASOME MATURATION PROTEIN protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115324469|UniProtKB=A0ACM8F488 A0ACM8F488 PTHR48082:SF2 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT ALPHA, MITOCHONDRIAL ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;proton channel activity#GO:0015252;monoatomic cation channel activity#GO:0005261;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;ATP binding#GO:0005524;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;ligase activity#GO:0016874;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;proton transmembrane transporter activity#GO:0015078;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate biosynthetic process#GO:1901293;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206 proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259 primary active transporter#PC00068;ATP synthase#PC00002 ATP synthesis#P02721>F1 alpha#P02791 IXOSC|EnsemblGenome=LOC121837234|UniProtKB=A0ACM8G2X8 A0ACM8G2X8 LOC121837234 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115316357|UniProtKB=A0ACM8G4U5 A0ACM8G4U5 LOC115316357 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8032111|UniProtKB=A0ACM8E0Z5 A0ACM8E0Z5 ced-6 PTHR11232:SF77 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER PTB DOMAIN-CONTAINING ENGULFMENT ADAPTER PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;transport#GO:0006810;membrane invagination#GO:0010324;phagocytosis#GO:0006909;membrane organization#GO:0061024;endocytosis#GO:0006897;cellular process#GO:0009987;cellular component organization#GO:0016043 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8050532|UniProtKB=A0ACM8EE09 A0ACM8EE09 LOC8050532 PTHR28547:SF1 PROTEIN MMS22-LIKE PROTEIN MMS22-LIKE response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 IXOSC|EnsemblGenome=LOC120841683|UniProtKB=A0ACM8ES99 A0ACM8ES99 LOC120841683 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8036482|UniProtKB=A0ACM8DX75 A0ACM8DX75 LOC8036482 PTHR11455:SF30 CRYPTOCHROME CRYPTOCHROME-1-LIKE ISOFORM X1 lyase activity#GO:0016829;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;carbon-carbon lyase activity#GO:0016830;DNA binding#GO:0003677;anion binding#GO:0043168;small molecule binding#GO:0036094;deoxyribodipyrimidine photo-lyase activity#GO:0003904;nucleic acid binding#GO:0003676;ion binding#GO:0043167;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of cellular process#GO:0050794;response to light stimulus#GO:0009416;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to radiation#GO:0009314;negative regulation of macromolecule metabolic process#GO:0010605;regulation of circadian rhythm#GO:0042752;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;response to external stimulus#GO:0009605;regulation of biosynthetic process#GO:0009889;photoperiodism#GO:0009648;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to abiotic stimulus#GO:0009628;circadian regulation of gene expression#GO:0032922;negative regulation of biological process#GO:0048519;circadian rhythm#GO:0007623;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;rhythmic process#GO:0048511;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 DNA photolyase#PC00014 IXOSC|EnsemblGenome=LOC8034653|UniProtKB=A0ACM8DJI0 A0ACM8DJI0 LOC8034653 PTHR22763:SF196 RING ZINC FINGER PROTEIN E3 UBIQUITIN-PROTEIN LIGASE SYNOVIOLIN acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8053112|UniProtKB=A0ACM8FT99 A0ACM8FT99 LOC8053112 PTHR23349:SF113 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST TRANSCRIPTION FACTOR 24-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8028899|UniProtKB=A0ACM8E7J2 A0ACM8E7J2 LOC8028899 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE-LIKE transferase#PC00220 IXOSC|EnsemblGenome=LOC8042373|UniProtKB=A0ACM8FER4 A0ACM8FER4 LOC8042373 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE catalytic activity#GO:0003824;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;alpha-glucosidase activity#GO:0090599;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC8023886|UniProtKB=A0ACM8DZ77 A0ACM8DZ77 Sod2 PTHR11404:SF6 SUPEROXIDE DISMUTASE 2 SUPEROXIDE DISMUTASE [MN], MITOCHONDRIAL antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121835506|UniProtKB=A0ACM8FUF0 A0ACM8FUF0 LOC121835506 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850422|UniProtKB=A0ACM8F8R3 A0ACM8F8R3 LOC120850422 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120842910|UniProtKB=A0ACM8EUY5 A0ACM8EUY5 LOC120842910 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC8027913|UniProtKB=A0ACM8EJJ7 A0ACM8EJJ7 LOC8027913 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293 sodium ion transport#GO:0006814;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115329808|UniProtKB=A0ACM8FB26 A0ACM8FB26 LOC115329808 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC121833206|UniProtKB=A0ACM8FKT5 A0ACM8FKT5 LOC121833206 PTHR46481:SF16 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 BED-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837617|UniProtKB=A0ACM8FVA4 A0ACM8FVA4 LOC120837617 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841697|UniProtKB=A0ACM8ES52 A0ACM8ES52 LOC120841697 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033414|UniProtKB=A0ACM8DQH1 A0ACM8DQH1 LOC8033414 PTHR10811:SF134 FRINGE-RELATED FRINGE GLYCOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;acetylglucosaminyltransferase activity#GO:0008375 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of response to stimulus#GO:0048583 glycosyltransferase#PC00111;transferase#PC00220 Notch signaling pathway#P00045>Fringe#P01107 IXOSC|EnsemblGenome=LOC115319728|UniProtKB=A0ACM8G4V6 A0ACM8G4V6 LOC115319728 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8032429|UniProtKB=A0ACM8F752 A0ACM8F752 LOC8032429 PTHR33492:SF21 OSJNBA0043A12.37 PROTEIN-RELATED MYB_SANT-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023246|UniProtKB=A0ACM8DGK7 A0ACM8DGK7 LOC8023246 PTHR16489:SF12 GH11727P GH11727P phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8026703|UniProtKB=A0ACM8E4B8 A0ACM8E4B8 LOC8026703 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121046967|UniProtKB=A0ACM8FF83 A0ACM8FF83 LOC121046967 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC chromatin binding#GO:0003682;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC115326488|UniProtKB=A0ACM8E5Z0 A0ACM8E5Z0 LOC115326488 PTHR11086:SF23 DEOXYCYTIDYLATE DEAMINASE-RELATED DEOXYCYTIDYLATE DEAMINASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239 nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleoside monophosphate biosynthetic process#GO:0009124;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;deaminase#PC00088 IXOSC|EnsemblGenome=LOC8041813|UniProtKB=A0ACM8FKH9 A0ACM8FKH9 LOC8041813 PTHR45636:SF56 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED EYEGONE, ISOFORM A-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC120836885|UniProtKB=A0ACM8EFM5 A0ACM8EFM5 LOC120836885 PTHR12332:SF1 KEREN-RELATED KEREN-RELATED signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154 IXOSC|EnsemblGenome=LOC120850578|UniProtKB=A0ACM8FAH3 A0ACM8FAH3 LOC120850578 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318650|UniProtKB=A0ACM8EW71 A0ACM8EW71 LOC115318650 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120839728|UniProtKB=A0ACM8EMP4 A0ACM8EMP4 LOC120839728 PTHR11145:SF8 BTB/POZ DOMAIN-CONTAINING ADAPTER FOR CUL3-MEDIATED RHOA DEGRADATION PROTEIN FAMILY MEMBER RE57120P scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8032458|UniProtKB=A0ACM8FVA2 A0ACM8FVA2 LOC8032458 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8028064|UniProtKB=A0ACM8DPA8 A0ACM8DPA8 PolD2 PTHR10416:SF0 DNA POLYMERASE DELTA SUBUNIT 2 DNA POLYMERASE DELTA SUBUNIT 2 enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;DNA synthesis involved in DNA replication#GO:0090592;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;replication fork#GO:0005657;replisome#GO:0030894;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;protein-DNA complex#GO:0032993;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 IXOSC|EnsemblGenome=LOC120839699|UniProtKB=A0ACM8ELX3 A0ACM8ELX3 LOC120839699 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8041710|UniProtKB=A0ACM8G6T0 A0ACM8G6T0 LOC8041710 PTHR45677:SF10 GLUTAMATE DECARBOXYLASE-RELATED GLUTAMATE DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Gamma-aminobutyric acid synthesis#P04384>Glutamate decarboxylase#P04482 IXOSC|EnsemblGenome=LOC115319408|UniProtKB=A0ACM8EQL3 A0ACM8EQL3 LOC115319408 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115321121|UniProtKB=A0ACM8E1R2 A0ACM8E1R2 l(3)87Df PTHR31586:SF1 CYTOCHROME C OXIDASE PROTEIN 20 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX20, MITOCHONDRIAL cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC115329275|UniProtKB=A0ACM8EA95 A0ACM8EA95 LOC115329275 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121836499|UniProtKB=A0ACM8FYZ7 A0ACM8FYZ7 LOC121836499 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8034582|UniProtKB=A0ACM8DJG2 A0ACM8DJG2 LOC8034582 PTHR14200:SF11 CYTOCHROME C OXIDASE POLYPEPTIDE CYTOCHROME C OXIDASE SUBUNIT 5A, MITOCHONDRIAL electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;metabolic process#GO:0008152;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex IV#GO:0045277;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;oxidase#PC00175 IXOSC|EnsemblGenome=LOC8025189|UniProtKB=A0ACM8E7D9 A0ACM8E7D9 PTHR24088:SF0 28S RIBOSOMAL PROTEIN S17, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US17M mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120836071|UniProtKB=A0ACM8EUE1 A0ACM8EUE1 LOC120836071 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047731|UniProtKB=A0ACM8FGG9 A0ACM8FGG9 LOC121047731 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115320779|UniProtKB=A0ACM8F5T1 A0ACM8F5T1 LOC115320779 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120842782|UniProtKB=A0ACM8EUK7 A0ACM8EUK7 LOC120842782 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8036866|UniProtKB=A0ACM8ED28 A0ACM8ED28 Arpc1 PTHR10709:SF2 ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 1 ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cortical actin cytoskeleton organization#GO:0030866 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 Integrin signalling pathway#P00034>Arp2/3#P00912;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Huntington disease#P00029>Arp2/3 complex#P00811 IXOSC|EnsemblGenome=LOC120849935|UniProtKB=A0ACM8F8P3 A0ACM8F8P3 LOC120849935 PTHR47217:SF1 GLOBIN-LIKE PROTEIN GLOBIN-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8032327|UniProtKB=A0ACM8E3I3 A0ACM8E3I3 SmD1 PTHR23338:SF18 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;spliceosomal snRNP complex#GO:0097525;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;U2 snRNP#GO:0005686;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115326690|UniProtKB=A0ACM8G5X0 A0ACM8G5X0 LOC115326690 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115322888|UniProtKB=A0ACM8E2K2 A0ACM8E2K2 LOC115322888 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8024564|UniProtKB=A0ACM8FCN3 A0ACM8FCN3 LOC8024564 PTHR19818:SF151 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN 76 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120839986|UniProtKB=A0ACM8EP47 A0ACM8EP47 LOC120839986 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115332424|UniProtKB=A0ACM8EJL8 A0ACM8EJL8 LOC115332424 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849445|UniProtKB=A0ACM8F6T1 A0ACM8F6T1 LOC120849445 PTHR21461:SF40 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN BETA-1,4-GALACTOSYLTRANSFERASE GALT-1 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8038771|UniProtKB=A0ACM8E263 A0ACM8E263 LOC8038771 PTHR10696:SF55 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;biosynthetic process#GO:0009058 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040636|UniProtKB=A0ACM8E2I6 A0ACM8E2I6 LOC8040636 PTHR44472:SF5 DDB1- AND CUL4-ASSOCIATED FACTOR 4-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 4 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 IXOSC|EnsemblGenome=LOC8042453|UniProtKB=A0ACM8FR30 A0ACM8FR30 LOC8042453 PTHR24228:SF63 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR MOODY transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8036305|UniProtKB=A0ACM8EJV9 A0ACM8EJV9 PTHR13167:SF48 PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT PIEZO-TYPE MECHANOSENSITIVE ION CHANNEL COMPONENT gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 cellular response to abiotic stimulus#GO:0071214;regulation of membrane potential#GO:0042391;response to external stimulus#GO:0009605;regulation of biological quality#GO:0065008;detection of mechanical stimulus#GO:0050982;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;biological regulation#GO:0065007;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;response to mechanical stimulus#GO:0009612;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC8036792|UniProtKB=A0ACM8DM46 A0ACM8DM46 LOC8036792 PTHR22741:SF10 P140CAP/SNIP-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN CG32809 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8053473|UniProtKB=A0ACM8EE03 A0ACM8EE03 LOC8053473 PTHR11751:SF29 ALANINE AMINOTRANSFERASE ALANINE TRANSAMINASE transaminase#PC00216;transferase#PC00220 IXOSC|EnsemblGenome=LOC8050910|UniProtKB=A0ACM8DLT3 A0ACM8DLT3 LOC8050910 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8051769|UniProtKB=A0ACM8DLE8 A0ACM8DLE8 LOC8051769 PTHR32073:SF7 GH11358P GH11358P IXOSC|EnsemblGenome=LOC8053547|UniProtKB=A0ACM8EUI9 A0ACM8EUI9 LOC8053547 PTHR10120:SF24 CAAX PRENYL PROTEASE 1 CAAX PRENYL PROTEASE 1 HOMOLOG metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8038224|UniProtKB=A0ACM8E8T1 A0ACM8E8T1 LOC8038224 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8030129|UniProtKB=A0ACM8EDA0 A0ACM8EDA0 MED16 PTHR13224:SF6 THYROID HORMONE RECEPTOR-ASSOCIATED PROTEIN-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 16 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC8031822|UniProtKB=A0ACM8EMH5 A0ACM8EMH5 LOC8031822 PTHR15672:SF8 CAMP-REGULATED PHOSPHOPROTEIN 21 RELATED R3H DOMAIN CONTAINING PROTEIN PROTEIN ENCORE IXOSC|EnsemblGenome=LOC120844712|UniProtKB=A0ACM8EZH0 A0ACM8EZH0 LOC120844712 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115328598|UniProtKB=A0ACM8E9C8 A0ACM8E9C8 LOC115328598 PTHR10858:SF23 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE II catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC115323850|UniProtKB=A0ACM8EHC1 A0ACM8EHC1 PTHR11349:SF116 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleoside triphosphate biosynthetic process#GO:0009142;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;cellular process#GO:0009987;nucleoside triphosphate metabolic process#GO:0009141;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 IXOSC|EnsemblGenome=LOC115320499|UniProtKB=A0ACM8E1B4 A0ACM8E1B4 LOC115320499 PTHR22589:SF99 CARNITINE O-ACYLTRANSFERASE CHOLINE_CARNITINE ACYLTRANSFERASE DOMAIN-CONTAINING PROTEIN acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115320304|UniProtKB=A0ACM8FSB5 A0ACM8FSB5 LOC115320304 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120849218|UniProtKB=A0ACM8FYE9 A0ACM8FYE9 LOC120849218 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120836035|UniProtKB=A0ACM8FU13 A0ACM8FU13 LOC120836035 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8033989|UniProtKB=A0ACM8DNA6 A0ACM8DNA6 LOC8033989 PTHR45814:SF2 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 HISTONE-LYSINE N-METHYLTRANSFERASE SETD1 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8051327|UniProtKB=A0ACM8EHN2 A0ACM8EHN2 LOC8051327 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846343|UniProtKB=A0ACM8F310 A0ACM8F310 LOC120846343 PTHR11073:SF2 CALRETICULIN AND CALNEXIN CALRETICULIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;protein folding#GO:0006457;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121837340|UniProtKB=A0ACM8G3A2 A0ACM8G3A2 LOC121837340 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8025599|UniProtKB=A0ACM8DSR5 A0ACM8DSR5 LOC8025599 PTHR11932:SF180 CULLIN CULLIN-3 ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;protein binding#GO:0005515;structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987 nucleus#GO:0005634;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115312702|UniProtKB=A0ACM8DSE5 A0ACM8DSE5 LOC115312702 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120837968|UniProtKB=A0ACM8EI79 A0ACM8EI79 LOC120837968 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8053244|UniProtKB=A0ACM8E5A3 A0ACM8E5A3 LOC8053244 PTHR10844:SF33 CAVEOLIN CAVEOLIN cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;membrane assembly#GO:0071709;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121046892|UniProtKB=A0ACM8FF90 A0ACM8FF90 LOC121046892 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031696|UniProtKB=A0ACM8FWP6 A0ACM8FWP6 LOC8031696 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115323826|UniProtKB=A0ACM8E426 A0ACM8E426 LOC115323826 PTHR10491:SF6 DTDP-4-DEHYDRORHAMNOSE REDUCTASE METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;biosynthetic process#GO:0009058 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 reductase#PC00198 O-antigen biosynthesis#P02757>dTDP-4-dehydrorhamnose reductase#P03050 IXOSC|EnsemblGenome=LOC8036289|UniProtKB=A0ACM8DHC3 A0ACM8DHC3 LOC8036289 PTHR10666:SF438 UBIQUITIN UBIQUITIN-RIBOSOMAL PROTEIN ES31 FUSION PROTEIN structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 IXOSC|EnsemblGenome=LOC8040777|UniProtKB=A0ACM8EFU5 A0ACM8EFU5 LOC8040777 PTHR12011:SF347 ADHESION G-PROTEIN COUPLED RECEPTOR LATROPHILIN CIRL cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8033018|UniProtKB=A0ACM8DXY4 A0ACM8DXY4 LOC8033018 PTHR16024:SF29 XK-RELATED PROTEIN XK-RELATED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121837356|UniProtKB=A0ACM8G2X5 A0ACM8G2X5 LOC121837356 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115326114|UniProtKB=A0ACM8E5G3 A0ACM8E5G3 LOC115326114 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120849196|UniProtKB=A0ACM8F879 A0ACM8F879 LOC120849196 PTHR11588:SF524 TUBULIN TUBULIN BETA CHAIN small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555 cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 tubulin#PC00228;cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 IXOSC|EnsemblGenome=LOC115318399|UniProtKB=A0ACM8DYF7 A0ACM8DYF7 LOC115318399 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053247|UniProtKB=A0ACM8E4Y0 A0ACM8E4Y0 LOC8053247 PTHR15683:SF8 SCAFFOLD ATTACHMENT FACTOR B-RELATED SCAFFOLD ATTACHMENT FACTOR B, ISOFORM B nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8027591|UniProtKB=A0ACM8EGN0 A0ACM8EGN0 LOC8027591 PTHR11010:SF128 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8041011|UniProtKB=A0ACM8ESY0 A0ACM8ESY0 LOC8041011 PTHR47117:SF16 STAR-RELATED LIPID TRANSFER PROTEIN 9 KINESIN-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120844749|UniProtKB=A0ACM8G651 A0ACM8G651 LOC120844749 PTHR24243:SF242 G-PROTEIN COUPLED RECEPTOR CNMAMIDE RECEPTOR-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8035647|UniProtKB=A0ACM8E1W5 A0ACM8E1W5 LOC8035647 PTHR12550:SF70 HEPATOMA-DERIVED GROWTH FACTOR-RELATED JIL-1 ANCHORING AND STABILIZING PROTEIN, ISOFORM A cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC121836977|UniProtKB=A0ACM8G140 A0ACM8G140 LOC121836977 PTHR11022:SF80 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LC-RELATED peptidoglycan muralytic activity#GO:0061783;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;pattern recognition receptor activity#GO:0038187;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023 defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;response to external stimulus#GO:0009605;defense response#GO:0006952;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8036865|UniProtKB=A0ACM8EE12 A0ACM8EE12 LOC8036865 PTHR16189:SF0 TRANSMEMBRANE PROTEIN 104-RELATED SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 12-RELATED IXOSC|EnsemblGenome=LOC8036137|UniProtKB=A0ACM8E3A1 A0ACM8E3A1 LOC8036137 PTHR13950:SF9 RABCONNECTIN-RELATED RABCONNECTIN-3A cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endosomal transport#GO:0016197;protein-containing complex organization#GO:0043933;intracellular transport#GO:0046907;transport#GO:0006810;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;early endosome to late endosome transport#GO:0045022;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8039025|UniProtKB=A0ACM8E3L1 A0ACM8E3L1 LOC8039025 PTHR43884:SF11 ACYL-COA DEHYDROGENASE VERY LONG-CHAIN ACYL-COA DEHYDROGENASE, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;lipid binding#GO:0008289;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC115326391|UniProtKB=A0ACM8F4T6 A0ACM8F4T6 LOC115326391 PTHR46380:SF2 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 CYCLIN-D-BINDING MYB-LIKE TRANSCRIPTION FACTOR 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120848991|UniProtKB=A0ACM8F742 A0ACM8F742 LOC120848991 PTHR46186:SF2 CYSTATIN CYSTATIN-RELATED molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;vesicle#GO:0031982 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8029946|UniProtKB=A0ACM8FYK2 A0ACM8FYK2 Vps15 PTHR17583:SF0 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 PHOSPHOINOSITIDE 3-KINASE REGULATORY SUBUNIT 4 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 establishment of localization#GO:0051234;pexophagy#GO:0000425;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;intracellular protein transport#GO:0006886;vacuolar transport#GO:0007034;vesicle-mediated transport#GO:0016192;macroautophagy#GO:0016236;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;cellular process#GO:0009987;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;protein localization to vacuole#GO:0072665;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;catabolic process#GO:0009056;late endosome to vacuole transport#GO:0045324 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;organelle membrane contact site#GO:0044232;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endosome#GO:0005768;phosphatidylinositol 3-kinase complex, class III#GO:0035032;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;transferase complex#GO:1990234;extrinsic component of membrane#GO:0019898 protein-binding activity modulator#PC00095;kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC120837942|UniProtKB=A0ACM8EJL6 A0ACM8EJL6 Lamtor4 PTHR33967:SF1 RAGULATOR COMPLEX PROTEIN LAMTOR4 RAGULATOR COMPLEX PROTEIN LAMTOR4 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;positive regulation of biological process#GO:0048518;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;response to chemical#GO:0042221;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8027378|UniProtKB=A0ACM8DQC1 A0ACM8DQC1 LOC8027378 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115315999|UniProtKB=A0ACM8DW17 A0ACM8DW17 LOC115315999 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;organelle organization#GO:0006996 IXOSC|EnsemblGenome=LOC8037678|UniProtKB=A0ACM8FN34 A0ACM8FN34 PTHR24340:SF70 HOMEOBOX PROTEIN NKX NK7.1, ISOFORM A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC121046630|UniProtKB=A0ACM8FD75 A0ACM8FD75 PTHR46060:SF3 MARINER MOS1 TRANSPOSASE-LIKE PROTEIN PROTEIN GVQW3 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115308192|UniProtKB=A0ACM8DYL4 A0ACM8DYL4 Cdc23 PTHR12558:SF10 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 23 HOMOLOG enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of mitotic nuclear division#GO:0007088;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;regulation of mitotic metaphase/anaphase transition#GO:0030071;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;cell division#GO:0051301;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;regulation of chromosome separation#GO:1905818;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;protein catabolic process#GO:0030163;positive regulation of cellular component organization#GO:0051130;anaphase-promoting complex-dependent catabolic process#GO:0031145;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of organelle organization#GO:0033043 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8027499|UniProtKB=A0ACM8FIN2 A0ACM8FIN2 LOC8027499 PTHR11475:SF106 OXIDASE/PEROXIDASE CURLY SU antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC8042383|UniProtKB=A0ACM8EVJ1 A0ACM8EVJ1 LOC8042383 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8033543|UniProtKB=A0ACM8DI36 A0ACM8DI36 LOC8033543 PTHR31186:SF1 MODULATOR OF SMOOTHENED PROTEIN MODULATOR OF SMOOTHENED PROTEIN negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;ciliary membrane#GO:0060170;cilium#GO:0005929;intracellular organelle#GO:0043229;cell projection membrane#GO:0031253;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025 IXOSC|EnsemblGenome=LOC115313790|UniProtKB=A0ACM8DT73 A0ACM8DT73 LOC115313790 PTHR45902:SF7 LATROPHILIN RECEPTOR-LIKE PROTEIN A G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8051413|UniProtKB=A0ACM8DS67 A0ACM8DS67 garnet PTHR22781:SF14 DELTA ADAPTIN-RELATED AP-3 COMPLEX SUBUNIT DELTA-1 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;protein targeting to vacuole#GO:0006623;synaptic vesicle transport#GO:0048489;endomembrane system organization#GO:0010256;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;endosomal transport#GO:0016197;microtubule-based process#GO:0007017;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;protein localization to lysosome#GO:0061462;cellular component organization#GO:0016043;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;establishment of organelle localization#GO:0051656;microtubule-based transport#GO:0099111;lysosomal transport#GO:0007041;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;cellular localization#GO:0051641;vesicle localization#GO:0051648;macromolecule localization#GO:0033036;axo-dendritic transport#GO:0008088;synaptic vesicle membrane organization#GO:0048499;membrane organization#GO:0061024;synaptic vesicle recycling#GO:0036465;cytoskeleton-dependent intracellular transport#GO:0030705;vacuolar transport#GO:0007034;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;anterograde synaptic vesicle transport#GO:0048490;vesicle cytoskeletal trafficking#GO:0099518;intracellular protein localization#GO:0008104;vesicle budding from membrane#GO:0006900;establishment of protein localization to organelle#GO:0072594;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;protein localization to organelle#GO:0033365;microtubule-based movement#GO:0007018;endosome to lysosome transport#GO:0008333;axonal transport#GO:0098930;protein localization to vacuole#GO:0072665;organelle localization#GO:0051640;anterograde axonal transport#GO:0008089;localization#GO:0051179;Golgi to vacuole transport#GO:0006896 axon terminus#GO:0043679;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;axon#GO:0030424;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;vesicle#GO:0031982;membrane protein complex#GO:0098796;distal axon#GO:0150034;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;neuron projection terminus#GO:0044306;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;cell junction#GO:0030054;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;coated membrane#GO:0048475;intracellular vesicle#GO:0097708;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226 transporter#PC00227 IXOSC|EnsemblGenome=LOC8039882|UniProtKB=A0ACM8E2P9 A0ACM8E2P9 PTHR15184:SF88 ATP SYNTHASE ATP SYNTHASE F(1) COMPLEX SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 ATP synthase#PC00002 ATP synthesis#P02721>F1 beta#P02794 IXOSC|EnsemblGenome=LOC120842558|UniProtKB=A0ACM8EU33 A0ACM8EU33 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8053014|UniProtKB=A0ACM8FWW0 A0ACM8FWW0 LOC8053014 PTHR48075:SF5 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN 3-HYDROXYBUTYRYL-COA DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053001|UniProtKB=A0ACM8FPZ0 A0ACM8FPZ0 PTHR45828:SF40 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE REELIN DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8041153|UniProtKB=A0ACM8E1S8 A0ACM8E1S8 LOC8041153 PTHR46461:SF1 KELCH DOMAIN-CONTAINING PROTEIN 3 KELCH DOMAIN-CONTAINING PROTEIN 3 chromatin binding#GO:0003682;binding#GO:0005488 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8031304|UniProtKB=A0ACM8DI34 A0ACM8DI34 LOC8031304 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC120844320|UniProtKB=A0ACM8EYD2 A0ACM8EYD2 LOC120844320 PTHR11778:SF7 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;RNA binding#GO:0003723 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8030498|UniProtKB=A0ACM8FW24 A0ACM8FW24 LOC8030498 PTHR47977:SF18 RAS-RELATED PROTEIN RAB RAS-RELATED PROTEIN RAB-36 ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120846228|UniProtKB=A0ACM8F1S5 A0ACM8F1S5 LOC120846228 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833002|UniProtKB=A0ACM8G610 A0ACM8G610 LOC121833002 PTHR13140:SF802 MYOSIN MYOSIN 95E, ISOFORM E cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 cellular process#GO:0009987;actin filament-based movement#GO:0030048;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;endocytosis#GO:0006897;transport#GO:0006810;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC121834706|UniProtKB=A0ACM8FQJ1 A0ACM8FQJ1 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;hexose metabolic process#GO:0019318 glycosidase#PC00110;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115326011|UniProtKB=A0ACM8G3V3 A0ACM8G3V3 LOC115326011 PTHR45823:SF1 T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN SAP DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840113|UniProtKB=A0ACM8ENR9 A0ACM8ENR9 LOC120840113 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028106|UniProtKB=A0ACM8EF51 A0ACM8EF51 LOC8028106 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8032259|UniProtKB=A0ACM8EQZ3 A0ACM8EQZ3 LOC8032259 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC121837288|UniProtKB=A0ACM8G2P6 A0ACM8G2P6 LOC121837288 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836471|UniProtKB=A0ACM8EF35 A0ACM8EF35 LOC120836471 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115315569|UniProtKB=A0ACM8DV09 A0ACM8DV09 LOC115315569 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8036855|UniProtKB=A0ACM8G3A6 A0ACM8G3A6 LOC8036855 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121833959|UniProtKB=A0ACM8FNG4 A0ACM8FNG4 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121832854|UniProtKB=A0ACM8E5F2 A0ACM8E5F2 LOC121832854 PTHR13124:SF12 39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN ML46 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8030785|UniProtKB=A0ACM8E5X2 A0ACM8E5X2 Mulk PTHR12358:SF116 SPHINGOSINE KINASE ACYLGLYCEROL KINASE, MITOCHONDRIAL lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;primary metabolic process#GO:0044238;sphingoid biosynthetic process#GO:0046520;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 transferase#PC00220;kinase#PC00137;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041589|UniProtKB=A0ACM8F6Q7 A0ACM8F6Q7 LOC8041589 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120844827|UniProtKB=A0ACM8EZM8 A0ACM8EZM8 LOC120844827 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834673|UniProtKB=A0ACM8FPG0 A0ACM8FPG0 PTHR24412:SF396 KELCH PROTEIN INFLUENZA VIRUS NS1A-BINDING PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120849614|UniProtKB=A0ACM8FLY6 A0ACM8FLY6 PTHR12890:SF0 DREV PROTEIN PROTEIN-L-HISTIDINE N-PROS-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC8032443|UniProtKB=A0ACM8EAW6 A0ACM8EAW6 LOC8032443 PTHR10132:SF14 ALPHA-/EPSILON-SARCOGLYCAN FAMILY MEMBER SARCOGLYCAN ALPHA, ISOFORM C cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;dystrophin-associated glycoprotein complex#GO:0016010;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 cadherin#PC00057 IXOSC|EnsemblGenome=LOC8031711|UniProtKB=A0ACM8E8Q8 A0ACM8E8Q8 LOC8031711 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115323501|UniProtKB=A0ACM8G418 A0ACM8G418 LOC115323501 PTHR46070:SF1 PINSTRIPE, ISOFORM A PINSTRIPE, ISOFORM A guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 IXOSC|EnsemblGenome=LOC115319195|UniProtKB=A0ACM8EZ26 A0ACM8EZ26 LOC115319195 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8026332|UniProtKB=A0ACM8DMN1 A0ACM8DMN1 LOC8026332 PTHR13386:SF1 HISTONE PARYLATION FACTOR 1 HISTONE PARYLATION FACTOR 1 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488;carbohydrate derivative binding#GO:0097367 cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;chromatin remodeling#GO:0006338;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8042696|UniProtKB=A0ACM8DKZ0 A0ACM8DKZ0 PQBP1 PTHR21737:SF3 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 POLYGLUTAMINE-BINDING PROTEIN 1 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear body#GO:0016604;membraneless organelle#GO:0043228 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8033634|UniProtKB=A0ACM8ECY4 A0ACM8ECY4 LOC8033634 PTHR18934:SF119 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE A nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8027434|UniProtKB=A0ACM8DVP6 A0ACM8DVP6 Abp1 PTHR10829:SF58 CORTACTIN AND DREBRIN DREBRIN-LIKE PROTEIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of organelle organization#GO:0033043;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840 cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin filament#GO:0005884;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;lamellipodium#GO:0030027;supramolecular complex#GO:0099080;glutamatergic synapse#GO:0098978;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;cell leading edge#GO:0031252;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;site of polarized growth#GO:0030427;intracellular organelle#GO:0043229;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC121834076|UniProtKB=A0ACM8FP46 A0ACM8FP46 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC115331492|UniProtKB=A0ACM8G3F7 A0ACM8G3F7 LOC115331492 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 IXOSC|EnsemblGenome=LOC115324251|UniProtKB=A0ACM8E4N4 A0ACM8E4N4 Had1 PTHR48075:SF1 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN LAMBDA-CRYSTALLIN HOMOLOG oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8025328|UniProtKB=A0ACM8DJ52 A0ACM8DJ52 LOC8025328 PTHR10985:SF77 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED PROTEIN HAIRY RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regionalization#GO:0003002;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of neurogenesis#GO:0050767;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of developmental process#GO:0050793;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 IXOSC|EnsemblGenome=LOC115314651|UniProtKB=A0ACM8DUF7 A0ACM8DUF7 LOC115314651 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115309120|UniProtKB=A0ACM8DND7 A0ACM8DND7 LOC115309120 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115330522|UniProtKB=A0ACM8EBU3 A0ACM8EBU3 LOC115330522 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8054016|UniProtKB=A0ACM8DLX6 A0ACM8DLX6 LOC8054016 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8031971|UniProtKB=A0ACM8G2D0 A0ACM8G2D0 JMJD5 PTHR12461:SF106 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED BIFUNCTIONAL PEPTIDASE AND ARGINYL-HYDROXYLASE JMJD5 binding#GO:0005488;chromatin binding#GO:0003682;dioxygenase activity#GO:0051213;histone modifying activity#GO:0140993;catalytic activity#GO:0003824;histone demethylase activity#GO:0032452;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;protein demethylase activity#GO:0140457;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;demethylase activity#GO:0032451 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115313855|UniProtKB=A0ACM8FNK4 A0ACM8FNK4 PTHR46290:SF1 DI-N-ACETYLCHITOBIASE DI-N-ACETYLCHITOBIASE IXOSC|EnsemblGenome=LOC8041118|UniProtKB=A0ACM8DKM2 A0ACM8DKM2 LOC8041118 PTHR12892:SF17 FGF RECEPTOR ACTIVATING PROTEIN 1 POST-GPI ATTACHMENT TO PROTEINS FACTOR 2-LIKE glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115327629|UniProtKB=A0ACM8E8P5 A0ACM8E8P5 LOC115327629 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120843960|UniProtKB=A0ACM8EYD5 A0ACM8EYD5 LOC120843960 PTHR24256:SF579 TRYPTASE-RELATED WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115317267|UniProtKB=A0ACM8G887 A0ACM8G887 LOC115317267 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308427|UniProtKB=A0ACM8ENC6 A0ACM8ENC6 LOC115308427 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 cellular localization#GO:0051641;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;endomembrane system organization#GO:0010256;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;establishment of localization#GO:0051234;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;transport#GO:0006810;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;membrane organization#GO:0061024;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC8038523|UniProtKB=A0ACM8DP44 A0ACM8DP44 LOC8038523 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115310523|UniProtKB=A0ACM8G932 A0ACM8G932 LOC115310523 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043073|UniProtKB=A0ACM8DR61 A0ACM8DR61 LOC8043073 PTHR13347:SF1 HEAT REPEAT-CONTAINING PROTEIN 3 HEAT REPEAT-CONTAINING PROTEIN 3 ribonucleoprotein complex biogenesis#GO:0022613;protein localization to organelle#GO:0033365;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 IXOSC|EnsemblGenome=LOC120843988|UniProtKB=A0ACM8EX57 A0ACM8EX57 LOC120843988 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8033160|UniProtKB=A0ACM8DV30 A0ACM8DV30 LOC8033160 PTHR11571:SF150 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC120842068|UniProtKB=A0ACM8FQ24 A0ACM8FQ24 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836134|UniProtKB=A0ACM8EPP8 A0ACM8EPP8 LOC120836134 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120850902|UniProtKB=A0ACM8FB63 A0ACM8FB63 LOC120850902 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC120844778|UniProtKB=A0ACM8EZN5 A0ACM8EZN5 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120843124|UniProtKB=A0ACM8EVA1 A0ACM8EVA1 LOC120843124 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC115320512|UniProtKB=A0ACM8E0X0 A0ACM8E0X0 LOC115320512 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC121835990|UniProtKB=A0ACM8FXU9 A0ACM8FXU9 LOC121835990 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8041691|UniProtKB=A0ACM8DRW4 A0ACM8DRW4 LOC8041691 PTHR13234:SF82 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE-LIKE PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8052086|UniProtKB=A0ACM8DM11 A0ACM8DM11 Manf PTHR12990:SF5 ARMET-LIKE PROTEIN MESENCEPHALIC ASTROCYTE-DERIVED NEUROTROPHIC FACTOR HOMOLOG growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8053962|UniProtKB=A0ACM8FDQ6 A0ACM8FDQ6 Paf-AHalpha PTHR11852:SF0 PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE IB SUBUNIT BETA HOMOLOG protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120842593|UniProtKB=A0ACM8EV86 A0ACM8EV86 LOC120842593 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8031560|UniProtKB=A0ACM8E5F8 A0ACM8E5F8 Oat PTHR11986:SF126 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;arginine metabolic process#GO:0006525;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 transaminase#PC00216 IXOSC|EnsemblGenome=LOC120837823|UniProtKB=A0ACM8EJ45 A0ACM8EJ45 LOC120837823 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8039327|UniProtKB=A0ACM8FHI1 A0ACM8FHI1 Rev1 PTHR45990:SF1 DNA REPAIR PROTEIN REV1 TRANSLESION SYNTHESIS PROTEIN REV1 DNA-directed DNA polymerase activity#GO:0003887;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259 site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8025300|UniProtKB=A0ACM8E231 A0ACM8E231 LOC8025300 PTHR10962:SF1 INTEGRAL TRANSMEMBRANE PROTEIN 2 INTEGRAL MEMBRANE PROTEIN 2 binding#GO:0005488;peptide binding#GO:0042277 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115322563|UniProtKB=A0ACM8E277 A0ACM8E277 LOC115322563 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8052493|UniProtKB=A0ACM8DP56 A0ACM8DP56 Hap40 PTHR16797:SF4 FACTOR VIII-ASSOCIATED GENE 1 40-KDA HUNTINGTIN-ASSOCIATED PROTEIN cytoskeleton-dependent intracellular transport#GO:0030705;establishment of organelle localization#GO:0051656;establishment of vesicle localization#GO:0051650;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;intracellular transport#GO:0046907;organelle localization#GO:0051640;transport#GO:0006810 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8027801|UniProtKB=A0ACM8DJE8 A0ACM8DJE8 LOC8027801 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115329774|UniProtKB=A0ACM8EAH5 A0ACM8EAH5 LOC115329774 PTHR24243:SF238 G-PROTEIN COUPLED RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120838588|UniProtKB=A0ACM8EJK0 A0ACM8EJK0 LOC120838588 PTHR36685:SF1 FLAGELLAR ATTACHMENT ZONE PROTEIN 1 CONSERVED DOMAIN-CONTAINING PROTEIN FLAGELLAR ATTACHMENT ZONE PROTEIN 1 CONSERVED DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846899|UniProtKB=A0ACM8F2P6 A0ACM8F2P6 LOC120846899 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8023867|UniProtKB=A0ACM8E4X0 A0ACM8E4X0 LOC8023867 PTHR12381:SF56 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN U FAMILY MEMBER B30.2_SPRY DOMAIN-CONTAINING PROTEIN-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8024656|UniProtKB=A0ACM8DIH6 A0ACM8DIH6 Spf30 PTHR13681:SF26 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC121833121|UniProtKB=A0ACM8FIB4 A0ACM8FIB4 LOC121833121 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8035632|UniProtKB=A0ACM8DJV1 A0ACM8DJV1 LOC8035632 PTHR21646:SF107 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 positive regulation of signaling#GO:0023056;regulation of biological quality#GO:0065008;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosome organization#GO:0007032;positive regulation of Wnt signaling pathway#GO:0030177;intracellular signaling cassette#GO:0141124;endomembrane system organization#GO:0010256;regulation of canonical Wnt signaling pathway#GO:0060828;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein stability#GO:0031647;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;positive regulation of cellular process#GO:0048522 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8024121|UniProtKB=A0ACM8DY56 A0ACM8DY56 LOC8024121 PTHR42938:SF22 FORMATE DEHYDROGENASE 1 D-3-PHOSPHOGLYCERATE DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176;dehydrogenase#PC00092 Serine glycine biosynthesis#P02776>Phosphoglycerate dehydrogenase#P03160 IXOSC|EnsemblGenome=LOC120836105|UniProtKB=A0ACM8EWY9 A0ACM8EWY9 LOC120836105 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120840863|UniProtKB=A0ACM8EQM6 A0ACM8EQM6 LOC120840863 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037728|UniProtKB=A0ACM8DI88 A0ACM8DI88 MED31 PTHR13186:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 31 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC115318145|UniProtKB=A0ACM8DY66 A0ACM8DY66 LOC115318145 PTHR21230:SF89 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 vesicle fusion#GO:0006906;catabolic process#GO:0009056;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;localization#GO:0051179;Golgi to vacuole transport#GO:0006896;membrane organization#GO:0061024;macroautophagy#GO:0016236;membrane fusion#GO:0061025;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;post-Golgi vesicle-mediated transport#GO:0006892;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;endosomal transport#GO:0016197;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152 vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;ER to Golgi transport vesicle membrane#GO:0012507;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endoplasmic reticulum#GO:0005783;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588 SNARE protein#PC00034;membrane traffic protein#PC00150 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 IXOSC|EnsemblGenome=LOC115323689|UniProtKB=A0ACM8F2M8 A0ACM8F2M8 LOC115323689 PTHR22984:SF33 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE 1 protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120841468|UniProtKB=A0ACM8FLG6 A0ACM8FLG6 LOC120841468 PTHR24215:SF38 RHO-GTPASE-ACTIVATING PROTEIN LRG1 CYSTEINE AND GLYCINE-RICH PROTEIN 1 structural molecule activity#GO:0005198;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;striated muscle cell development#GO:0055002;animal gross anatomical part developmental process#GO:0160108;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular anatomical entity morphogenesis#GO:0032989;muscle structure development#GO:0061061;actin cytoskeleton organization#GO:0030036;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;anatomical structure development#GO:0048856;muscle tissue development#GO:0060537;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;tissue development#GO:0009888;cellular developmental process#GO:0048869;developmental process#GO:0032502 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;Z disc#GO:0030018;nucleus#GO:0005634;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;sarcomere#GO:0030017;I band#GO:0031674;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;myofibril#GO:0030016;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC120850120|UniProtKB=A0ACM8FKC8 A0ACM8FKC8 LOC120850120 PTHR43347:SF5 ACYL-COA SYNTHETASE ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ligase#PC00142;metabolite interconversion enzyme#PC00262 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 IXOSC|EnsemblGenome=LOC121833390|UniProtKB=A0ACM8FKQ2 A0ACM8FKQ2 LOC121833390 PTHR10907:SF47 REGUCALCIN REGUCALCIN catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of calcium-mediated signaling#GO:0050848;regulation of signal transduction#GO:0009966;regulation of biological process#GO:0050789;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 esterase#PC00097;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041241|UniProtKB=A0ACM8DS97 A0ACM8DS97 LOC8041241 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120838975|UniProtKB=A0ACM8EKZ8 A0ACM8EKZ8 LOC120838975 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8040161|UniProtKB=A0ACM8EQ63 A0ACM8EQ63 GEFmeso PTHR45924:SF2 FI17866P1 FI17866P1 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;enzyme binding#GO:0019899 IXOSC|EnsemblGenome=LOC115327979|UniProtKB=A0ACM8EY74 A0ACM8EY74 LOC115327979 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8028866|UniProtKB=A0ACM8DNF7 A0ACM8DNF7 Rilpl PTHR21502:SF4 ZINC FINGER PROTEIN DZIP1 RILP-LIKE PROTEIN HOMOLOG protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488;enzyme binding#GO:0019899 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC115324188|UniProtKB=A0ACM8EUW4 A0ACM8EUW4 LOC115324188 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838859|UniProtKB=A0ACM8FDU8 A0ACM8FDU8 LOC120838859 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034676|UniProtKB=A0ACM8F836 A0ACM8F836 LOC8034676 PTHR46624:SF4 AGAP002036-PA ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 1-LIKE ISOFORM X1 small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;phospholipid binding#GO:0005543;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;lipid droplet organization#GO:0034389;cellular component assembly#GO:0022607;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;lipid storage#GO:0019915 intracellular organelle#GO:0043229;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120838969|UniProtKB=A0ACM8EKE5 A0ACM8EKE5 LOC120838969 PTHR24365:SF555 TOLL-LIKE RECEPTOR MSTPROX-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115318349|UniProtKB=A0ACM8F9F6 A0ACM8F9F6 LOC115318349 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8025703|UniProtKB=A0ACM8G2B5 A0ACM8G2B5 Ctl2 PTHR12385:SF14 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8050484|UniProtKB=A0ACM8E4A2 A0ACM8E4A2 PTHR26312:SF87 TETRATRICOPEPTIDE REPEAT PROTEIN 5 TETRATRICOPEPTIDE REPEAT PROTEIN 5 IXOSC|EnsemblGenome=LOC120840309|UniProtKB=A0ACM8EP48 A0ACM8EP48 LOC120840309 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8041186|UniProtKB=A0ACM8DV05 A0ACM8DV05 nudC PTHR12356:SF3 NUCLEAR MOVEMENT PROTEIN NUDC NUCLEAR MIGRATION PROTEIN NUDC metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8028631|UniProtKB=A0ACM8E620 A0ACM8E620 LOC8028631 PTHR37686:SF1 LD36006P LD36006P IXOSC|EnsemblGenome=LOC120844227|UniProtKB=A0ACM8EZ89 A0ACM8EZ89 LOC120844227 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8040957|UniProtKB=A0ACM8FDD2 A0ACM8FDD2 LOC8040957 PTHR10543:SF158 BETA-CAROTENE DIOXYGENASE RETINAL MUELLER CELLS ISOMEROHYDROLASE-LIKE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 isoprenoid metabolic process#GO:0006720;catabolic process#GO:0009056;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8039349|UniProtKB=A0ACM8DTB2 A0ACM8DTB2 l(1)G0320 PTHR12924:SF0 TRANSLOCON-ASSOCIATED PROTEIN, ALPHA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT ALPHA endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8027544|UniProtKB=A0ACM8DP09 A0ACM8DP09 Sec23 PTHR11141:SF0 PROTEIN TRANSPORT PROTEIN SEC23 PROTEIN TRANSPORT PROTEIN SEC23 enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114 membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;vesicle coat#GO:0030120;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated membrane#GO:0048475 membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC120846675|UniProtKB=A0ACM8F3U0 A0ACM8F3U0 LOC120846675 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045972|UniProtKB=A0ACM8FCJ6 A0ACM8FCJ6 LOC121045972 PTHR23430:SF50 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8029181|UniProtKB=A0ACM8DME8 A0ACM8DME8 LOC8029181 PTHR43053:SF4 GLYCOSIDASE FAMILY 31 RE74917P glucosidase#PC00108;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843473|UniProtKB=A0ACM8EW19 A0ACM8EW19 LOC120843473 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8037790|UniProtKB=A0ACM8FDV5 A0ACM8FDV5 ebo PTHR21452:SF4 EXPORTIN-6 EXPORTIN-6 nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;protein export from nucleus#GO:0006611 IXOSC|EnsemblGenome=LOC115314807|UniProtKB=A0ACM8F271 A0ACM8F271 LOC115314807 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849329|UniProtKB=A0ACM8FNT2 A0ACM8FNT2 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115331558|UniProtKB=A0ACM8F480 A0ACM8F480 LOC115331558 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850870|UniProtKB=A0ACM8FAX9 A0ACM8FAX9 LOC120850870 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115326121|UniProtKB=A0ACM8F8C2 A0ACM8F8C2 LOC115327568 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121048414|UniProtKB=A0ACM8FIE6 A0ACM8FIE6 LOC121048414 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030412|UniProtKB=A0ACM8G1J6 A0ACM8G1J6 LOC8030412 PTHR14856:SF9 PQ-LOOP REPEAT-CONTAINING PROTEIN 1-LIKE PROTEIN SOLUTE CARRIER FAMILY 66 MEMBER 2 phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;lipid transport#GO:0006869;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;localization#GO:0051179;lipid localization#GO:0010876 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;vesicle membrane#GO:0012506;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC120850863|UniProtKB=A0ACM8FYS2 A0ACM8FYS2 LOC120850863 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031621|UniProtKB=A0ACM8DTD0 A0ACM8DTD0 nAChRbeta1 PTHR18945:SF784 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-LIKE 1 gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, cholinergic#GO:0007271 transmembrane transporter complex#GO:1902495;postsynaptic membrane#GO:0045211;cellular anatomical structure#GO:0110165;synapse#GO:0045202;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;cell junction#GO:0030054;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>beta#P01095;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC120840343|UniProtKB=A0ACM8EPU6 A0ACM8EPU6 LOC120840343 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8033475|UniProtKB=A0ACM8G390 A0ACM8G390 rt PTHR10050:SF51 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 1 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115313048|UniProtKB=A0ACM8DSC7 A0ACM8DSC7 LOC115313048 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC120844213|UniProtKB=A0ACM8EY56 A0ACM8EY56 LOC120844213 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120843544|UniProtKB=A0ACM8EWD4 A0ACM8EWD4 LOC120843544 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8038192|UniProtKB=A0ACM8FJH3 A0ACM8FJH3 LOC8038192 PTHR21477:SF13 ZGC:172139 KIAA0930 IXOSC|EnsemblGenome=LOC120843892|UniProtKB=A0ACM8EX35 A0ACM8EX35 LOC120843892 PTHR11224:SF10 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115319211|UniProtKB=A0ACM8F846 A0ACM8F846 LOC115319211 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325908|UniProtKB=A0ACM8E5C2 A0ACM8E5C2 LOC115325908 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052637|UniProtKB=A0ACM8E1P1 A0ACM8E1P1 LOC8052637 PTHR14095:SF0 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED MIP22305P protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629 IXOSC|EnsemblGenome=LOC8035919|UniProtKB=A0ACM8E0D8 A0ACM8E0D8 LOC8035919 PTHR23073:SF155 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6B macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 proteasome complex#GO:0000502;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>19S proteasome#P01494;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC8032528|UniProtKB=A0ACM8FDF0 A0ACM8FDF0 LOC8032528 PTHR10357:SF237 ALPHA-GLUCOSIDASE FAMILY MEMBER ALPHA-GLUCOSIDASE oligosaccharide catabolic process#GO:0009313;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;amylase#PC00048 IXOSC|EnsemblGenome=LOC8029432|UniProtKB=A0ACM8EDX4 A0ACM8EDX4 LOC8029432 PTHR32123:SF13 BICD FAMILY-LIKE CARGO ADAPTER BICAUDAL D-RELATED PROTEIN HOMOLOG membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC115323829|UniProtKB=A0ACM8E3D1 A0ACM8E3D1 LOC115323829 PTHR46569:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRAIP E3 UBIQUITIN-PROTEIN LIGASE TRAIP catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;replication fork processing#GO:0031297;post-translational protein modification#GO:0043687;cellular process#GO:0009987;DNA-templated DNA replication#GO:0006261;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein modification process#GO:0036211;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification by small protein conjugation#GO:0032446;DNA replication#GO:0006260 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115333079|UniProtKB=A0ACM8EFC0 A0ACM8EFC0 LOC115333079 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115313446|UniProtKB=A0ACM8DSU2 A0ACM8DSU2 LOC115313446 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120838540|UniProtKB=A0ACM8EL28 A0ACM8EL28 LOC120838540 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316289|UniProtKB=A0ACM8ETM1 A0ACM8ETM1 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8051568|UniProtKB=A0ACM8E4H8 A0ACM8E4H8 Roe1 PTHR21237:SF23 GRPE PROTEIN GRPE PROTEIN HOMOLOG, MITOCHONDRIAL nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8026235|UniProtKB=A0ACM8EBI0 A0ACM8EBI0 LOC8026235 PTHR22914:SF42 CHITIN SYNTHASE CHITIN SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;chitin metabolic process#GO:0006030;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;biosynthetic process#GO:0009058;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;aminoglycan biosynthetic process#GO:0006023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 transferase#PC00220 IXOSC|EnsemblGenome=LOC115311423|UniProtKB=A0ACM8DR21 A0ACM8DR21 LOC115311423 PTHR24112:SF69 LEUCINE-RICH REPEAT, ISOFORM F-RELATED LEUCINE-RICH REPEAT, ISOFORM F regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cell migration#GO:0016477;cell motility#GO:0048870;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;regulation of actin filament organization#GO:0110053;regulation of actin nucleation#GO:0051125;regulation of actin filament-based process#GO:0032970 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;lamellipodium#GO:0030027;cell periphery#GO:0071944;membrane#GO:0016020;cell leading edge#GO:0031252 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8023435|UniProtKB=A0ACM8EA00 A0ACM8EA00 RhoGAP102A PTHR12635:SF7 RHO-GTPASE-ACTIVATING PROTEIN 6 FAMILY MEMBER RHO GTPASE ACTIVATING PROTEIN 36-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 PDGF signaling pathway#P00047>Rho#P01174 IXOSC|EnsemblGenome=LOC8037927|UniProtKB=A0ACM8DID1 A0ACM8DID1 Cisd2 PTHR13680:SF5 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 1 iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094;transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483 intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725 mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120836735|UniProtKB=A0ACM8EFR1 A0ACM8EFR1 LOC120836735 PTHR12670:SF21 CERAMIDASE NEUTRAL CERAMIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid catabolic process#GO:0016042;alcohol biosynthetic process#GO:0046165;ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120837011|UniProtKB=A0ACM8EH14 A0ACM8EH14 LOC120837011 PTHR47526:SF6 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115315620|UniProtKB=A0ACM8DVG1 A0ACM8DVG1 LOC115315620 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 IXOSC|EnsemblGenome=LOC121833713|UniProtKB=A0ACM8FMG7 A0ACM8FMG7 LOC121833713 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121833992|UniProtKB=A0ACM8FNK5 A0ACM8FNK5 PTHR10574:SF449 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;tissue development#GO:0009888;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 IXOSC|EnsemblGenome=LOC120850040|UniProtKB=A0ACM8F7W4 A0ACM8F7W4 LOC120850040 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053406|UniProtKB=A0ACM8DSY0 A0ACM8DSY0 LOC8053406 PTHR14387:SF7 THADA/DEATH RECEPTOR INTERACTING PROTEIN TRNA (32-2'-O)-METHYLTRANSFERASE REGULATOR THADA enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 RNA metabolic process#GO:0016070;methylation#GO:0032259;calcium ion homeostasis#GO:0055074;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;inorganic ion homeostasis#GO:0098771;tRNA modification#GO:0006400;intracellular monoatomic ion homeostasis#GO:0006873;tRNA processing#GO:0008033;intracellular calcium ion homeostasis#GO:0006874;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;chemical homeostasis#GO:0048878;gene expression#GO:0010467;RNA processing#GO:0006396;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA biosynthetic process#GO:0032774;homeostatic process#GO:0042592;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115326531|UniProtKB=A0ACM8ELV3 A0ACM8ELV3 LOC115326531 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115316657|UniProtKB=A0ACM8DWN5 A0ACM8DWN5 LOC115316657 PTHR23303:SF14 CARBOXYPEPTIDASE REGULATORY REGION-CONTAINING BOS COMPLEX SUBUNIT NOMO1-RELATED organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120843842|UniProtKB=A0ACM8EX27 A0ACM8EX27 LOC120843842 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8035626|UniProtKB=A0ACM8E2L2 A0ACM8E2L2 Tsr1 PTHR12858:SF1 RIBOSOME BIOGENESIS PROTEIN PRE-RRNA-PROCESSING PROTEIN TSR1 HOMOLOG hydrolase activity#GO:0016787;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8035097|UniProtKB=A0ACM8E7F9 A0ACM8E7F9 Trm1 PTHR10631:SF14 N 2 ,N 2 -DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE TRNA (GUANINE(26)-N(2))-DIMETHYLTRANSFERASE RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;tRNA (guanine) methyltransferase activity#GO:0016423;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC115312511|UniProtKB=A0ACM8DRU0 A0ACM8DRU0 LOC115312511 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 IXOSC|EnsemblGenome=LOC8040873|UniProtKB=A0ACM8FM39 A0ACM8FM39 LOC8040873 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115330729|UniProtKB=A0ACM8FIS3 A0ACM8FIS3 LOC115330729 PTHR14305:SF0 E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 E3 UBIQUITIN-PROTEIN LIGASE CCNB1IP1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;organelle fission#GO:0048285;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982 organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;synaptonemal structure#GO:0099086;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;synaptonemal complex#GO:0000795;condensed nuclear chromosome#GO:0000794 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8053806|UniProtKB=A0ACM8E8E8 A0ACM8E8E8 LOC8053806 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053365|UniProtKB=A0ACM8DQ00 A0ACM8DQ00 LOC8053365 PTHR11792:SF17 ARRESTIN KURTZ ARRESTIN signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of cell communication#GO:0010646;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;sensory perception#GO:0007600;regulation of signaling#GO:0023051;nervous system process#GO:0050877;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;localization#GO:0051179;cellular process#GO:0009987;receptor internalization#GO:0031623;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;negative regulation of response to stimulus#GO:0048585;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;transport#GO:0006810;negative regulation of cellular process#GO:0048523;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;import into cell#GO:0098657;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Wnt signaling pathway#P00057>beta-arrestin#P01456;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723 IXOSC|EnsemblGenome=LOC8039070|UniProtKB=A0ACM8DKB5 A0ACM8DKB5 Gp93 PTHR11528:SF144 HEAT SHOCK PROTEIN 90 FAMILY MEMBER ENDOPLASMIN ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 protein folding#GO:0006457;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;biosynthetic process#GO:0009058;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072;Hsp90 family chaperone#PC00028 IXOSC|EnsemblGenome=LOC121835695|UniProtKB=A0ACM8FVE4 A0ACM8FVE4 LOC121835695 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115323305|UniProtKB=A0ACM8FJW2 A0ACM8FJW2 LOC115323305 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120850034|UniProtKB=A0ACM8F7W0 A0ACM8F7W0 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8030336|UniProtKB=A0ACM8F6R4 A0ACM8F6R4 LOC8030336 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8029935|UniProtKB=A0ACM8DZS6 A0ACM8DZS6 Drep2 PTHR12306:SF22 CELL DEATH ACTIVATOR CIDE DNAATION FACTOR-RELATED PROTEIN 2, ISOFORM B lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 cellular component organization or biogenesis#GO:0071840;lipid droplet organization#GO:0034389;organelle fusion#GO:0048284;organelle organization#GO:0006996;cellular component organization#GO:0016043;programmed cell death#GO:0012501;lipid storage#GO:0019915;cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915 organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8043220|UniProtKB=A0ACM8EMA9 A0ACM8EMA9 LOC8043220 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8041448|UniProtKB=A0ACM8EFL2 A0ACM8EFL2 LOC8041448 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE 5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC115315268|UniProtKB=A0ACM8FRS4 A0ACM8FRS4 LOC115315268 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038638|UniProtKB=A0ACM8DU94 A0ACM8DU94 LOC8038638 PTHR14202:SF0 60 KDA RIBONUCLEOPROTEIN SSA/RO RNA-BINDING PROTEIN RO60 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8023877|UniProtKB=A0ACM8DHP0 A0ACM8DHP0 LOC8023877 PTHR24249:SF418 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120845306|UniProtKB=A0ACM8F1G4 A0ACM8F1G4 LOC120845306 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120838787|UniProtKB=A0ACM8EKP0 A0ACM8EKP0 LOC120838787 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8041637|UniProtKB=A0ACM8DT32 A0ACM8DT32 LOC8041637 PTHR46940:SF1 NKAP DOMAIN-CONTAINING 1 NKAP DOMAIN CONTAINING 1 IXOSC|EnsemblGenome=LOC115321051|UniProtKB=A0ACM8ERN4 A0ACM8ERN4 LOC115321051 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987 microbody#GO:0042579;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115313590|UniProtKB=A0ACM8F2F2 A0ACM8F2F2 LOC115313590 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115330816|UniProtKB=A0ACM8FA56 A0ACM8FA56 LOC115330816 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8041908|UniProtKB=A0ACM8E7K8 A0ACM8E7K8 LOC8041908 PTHR11562:SF17 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER LD05335P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115314159|UniProtKB=A0ACM8DTX2 A0ACM8DTX2 LOC115314159 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8036845|UniProtKB=A0ACM8DRP8 A0ACM8DRP8 PTHR24336:SF8 TRANSCRIPTION FACTOR LBX LADYBIRD EARLY-RELATED nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8052826|UniProtKB=A0ACM8DPF5 A0ACM8DPF5 LOC8052826 PTHR11255:SF125 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE THETA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 membrane#GO:0016020;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 IXOSC|EnsemblGenome=LOC8031669|UniProtKB=A0ACM8DXX5 A0ACM8DXX5 LOC8031669 PTHR22950:SF708 AMINO ACID TRANSPORTER SODIUM-COUPLED NEUTRAL AMINO ACID TRANSPORTER 11-RELATED transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8043373|UniProtKB=A0ACM8EC17 A0ACM8EC17 LOC8043373 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC121047617|UniProtKB=A0ACM8FYH9 A0ACM8FYH9 LOC121047617 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8029702|UniProtKB=A0ACM8FE11 A0ACM8FE11 LOC8029702 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8024680|UniProtKB=A0ACM8DVB3 A0ACM8DVB3 LOC8024680 PTHR23420:SF0 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;purine-containing compound metabolic process#GO:0072521;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121838314|UniProtKB=A0ACM8G7P5 A0ACM8G7P5 LOC121838314 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8051358|UniProtKB=A0ACM8FH12 A0ACM8FH12 LOC8051358 PTHR44281:SF6 SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG SPINDLE ASSEMBLY ABNORMAL PROTEIN 6 HOMOLOG cell cycle process#GO:0022402;centrosome cycle#GO:0007098;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;centriole replication#GO:0007099;organelle assembly#GO:0070925;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;cellular component organization or biogenesis#GO:0071840 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC115328930|UniProtKB=A0ACM8ETW1 A0ACM8ETW1 LOC115328930 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028657|UniProtKB=A0ACM8DNB6 A0ACM8DNB6 LOC8028657 PTHR18763:SF0 WD-REPEAT PROTEIN 18 WD REPEAT-CONTAINING PROTEIN 18 gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;RNA metabolic process#GO:0016070;DNA-templated DNA replication#GO:0006261;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoribonuclease complex#GO:1902555;intracellular organelle lumen#GO:0070013;pre-replicative complex#GO:0036387;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nuclear pre-replicative complex#GO:0005656;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348 IXOSC|EnsemblGenome=LOC8035877|UniProtKB=A0ACM8E5L1 A0ACM8E5L1 LOC8035877 PTHR13952:SF5 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;snRNA binding#GO:0017069;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U2-type prespliceosome#GO:0071004;spliceosomal complex#GO:0005681 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC121046591|UniProtKB=A0ACM8FFC3 A0ACM8FFC3 LOC121046591 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121836591|UniProtKB=A0ACM8FZ85 A0ACM8FZ85 LOC121836591 PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120836355|UniProtKB=A0ACM8EER0 A0ACM8EER0 LOC120836355 PTHR10953:SF6 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT catalytic activity, acting on a protein#GO:0140096;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657 post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 IXOSC|EnsemblGenome=LOC8037924|UniProtKB=A0ACM8DID0 A0ACM8DID0 Su(P) PTHR12782:SF5 MICROSOMAL PROSTAGLANDIN E SYNTHASE-2 PROSTAGLANDIN E SYNTHASE 2 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 reductase#PC00198;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115309359|UniProtKB=A0ACM8DNM0 A0ACM8DNM0 LOC115309359 PTHR12857:SF0 CXXC MOTIF CONTAINING ZINC BINDING PROTEIN CXXC MOTIF CONTAINING ZINC BINDING PROTEIN transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;zinc ion binding#GO:0008270;cation binding#GO:0043169;metal ion binding#GO:0046872 IXOSC|EnsemblGenome=LOC120844453|UniProtKB=A0ACM8EYR9 A0ACM8EYR9 LOC120844453 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323622|UniProtKB=A0ACM8E356 A0ACM8E356 LOC115323622 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to heat#GO:0009408;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;protein refolding#GO:0042026;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;protein folding#GO:0006457 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC115320344|UniProtKB=A0ACM8ENK5 A0ACM8ENK5 LOC115320344 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121834759|UniProtKB=A0ACM8FQS3 A0ACM8FQS3 LOC121834759 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8033783|UniProtKB=A0ACM8DPH5 A0ACM8DPH5 LOC8033783 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120847406|UniProtKB=A0ACM8F441 A0ACM8F441 LOC120847406 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051764|UniProtKB=A0ACM8DXY6 A0ACM8DXY6 DCTN2-p50 PTHR15346:SF0 DYNACTIN SUBUNIT DYNACTIN SUBUNIT 2 cytoskeletal adaptor activity#GO:0008093;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;organelle transport along microtubule#GO:0072384;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;mitotic cell cycle#GO:0000278;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;mitotic spindle organization#GO:0007052;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;nuclear migration#GO:0007097;cell cycle process#GO:0022402 actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC121835272|UniProtKB=A0ACM8FU39 A0ACM8FU39 LOC121835272 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115320914|UniProtKB=A0ACM8E1B6 A0ACM8E1B6 LOC115320914 PTHR45851:SF3 MYC PROTO-ONCOGENE MYC PROTO-ONCOGENE PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 p53 pathway feedback loops 2#P04398>Myc#P04649;Oxidative stress response#P00046>Myc#P01124;PDGF signaling pathway#P00047>c-Myc#P01172;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 IXOSC|EnsemblGenome=LOC115331242|UniProtKB=A0ACM8G3E2 A0ACM8G3E2 Adat1 PTHR46516:SF1 TRNA-SPECIFIC ADENOSINE DEAMINASE 1 TRNA-SPECIFIC ADENOSINE DEAMINASE 1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;tRNA-specific adenosine deaminase activity#GO:0008251;hydrolase activity#GO:0016787;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8032209|UniProtKB=A0ACM8DJ97 A0ACM8DJ97 LOC8032209 PTHR20208:SF10 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX1 hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 IXOSC|EnsemblGenome=LOC8031230|UniProtKB=A0ACM8FTT3 A0ACM8FTT3 LOC8031230 PTHR45080:SF45 CONTACTIN 5 IP11255P molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cell adhesion#GO:0007155;cell junction organization#GO:0034330;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005;axon#GO:0030424 IXOSC|EnsemblGenome=LOC120840385|UniProtKB=A0ACM8EP07 A0ACM8EP07 LOC120840385 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8038617|UniProtKB=A0ACM8FC47 A0ACM8FC47 LOC8038617 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115314758|UniProtKB=A0ACM8EP30 A0ACM8EP30 LOC115314758 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC8043965|UniProtKB=A0ACM8DL58 A0ACM8DL58 LOC8043965 PTHR47966:SF86 BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED BETA-SITE APP-CLEAVING ENZYME, ISOFORM A-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 cellular process#GO:0009987;cell death#GO:0008219;apoptotic process#GO:0006915;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;aspartic protease#PC00053 IXOSC|EnsemblGenome=LOC120840786|UniProtKB=A0ACM8EQ83 A0ACM8EQ83 LOC120840786 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024216|UniProtKB=A0ACM8F2X5 A0ACM8F2X5 LOC8024216 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC121045539|UniProtKB=A0ACM8FAB4 A0ACM8FAB4 LOC121045539 PTHR24252:SF46 ACROSIN-RELATED ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8040535|UniProtKB=A0ACM8ECQ8 A0ACM8ECQ8 LOC8040535 PTHR14619:SF3 NEURON-DERIVED NEUROTROPHIC FACTOR PROTEIN NDNF IXOSC|EnsemblGenome=LOC115328900|UniProtKB=A0ACM8E9B2 A0ACM8E9B2 LOC115328900 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120840392|UniProtKB=A0ACM8DXT1 A0ACM8DXT1 LOC120840392 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037514|UniProtKB=A0ACM8DWK6 A0ACM8DWK6 LOC8037514 PTHR12326:SF12 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN PLECKSTRIN HOMOLOGY AND RUN DOMAIN CONTAINING M1 IXOSC|EnsemblGenome=LOC120840367|UniProtKB=A0ACM8END2 A0ACM8END2 LOC120840367 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330456|UniProtKB=A0ACM8EBA2 A0ACM8EBA2 LOC115330456 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030951|UniProtKB=A0ACM8EKC0 A0ACM8EKC0 LOC8030951 PTHR10704:SF44 CARBOHYDRATE SULFOTRANSFERASE LD35051P-RELATED sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 amino sugar metabolic process#GO:0006040;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8042295|UniProtKB=A0ACM8DXI5 A0ACM8DXI5 LOC8042295 PTHR11360:SF238 MONOCARBOXYLATE TRANSPORTER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN monocarboxylic acid transmembrane transporter activity#GO:0008028;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;localization#GO:0051179;establishment of localization#GO:0051234;monocarboxylic acid transport#GO:0015718 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8053023|UniProtKB=A0ACM8DR03 A0ACM8DR03 SppL PTHR12174:SF22 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE-LIKE 3 aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;Golgi-associated vesicle#GO:0005798;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;Golgi-associated vesicle membrane#GO:0030660;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;side of membrane#GO:0098552 aspartic protease#PC00053;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8051082|UniProtKB=A0ACM8DLC6 A0ACM8DLC6 LOC8051082 PTHR10003:SF71 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN]-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;copper ion binding#GO:0005507 cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;cellular response to stimulus#GO:0051716;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to stress#GO:0006950 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120847627|UniProtKB=A0ACM8FHL7 A0ACM8FHL7 LOC120847627 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326765|UniProtKB=A0ACM8E720 A0ACM8E720 PTHR22930:SF289 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036787|UniProtKB=A0ACM8DZ75 A0ACM8DZ75 LOC8036787 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;nucleobase-containing compound kinase activity#GO:0019205;ATP binding#GO:0005524;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115332274|UniProtKB=A0ACM8EDD6 A0ACM8EDD6 LOC115332274 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034981|UniProtKB=A0ACM8FT34 A0ACM8FT34 LOC8034981 PTHR23282:SF158 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332459|UniProtKB=A0ACM8EE82 A0ACM8EE82 LOC115332459 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030628|UniProtKB=A0ACM8DSD3 A0ACM8DSD3 LOC8030628 PTHR46876:SF1 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 11 IXOSC|EnsemblGenome=LOC120836075|UniProtKB=A0ACM8F1S3 A0ACM8F1S3 LOC120836075 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120846893|UniProtKB=A0ACM8FYQ6 A0ACM8FYQ6 LOC120846893 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN system development#GO:0048731;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC121833237|UniProtKB=A0ACM8FKX8 A0ACM8FKX8 LOC121833237 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120845994|UniProtKB=A0ACM8F0J6 A0ACM8F0J6 LOC120845994 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115326903|UniProtKB=A0ACM8FYA8 A0ACM8FYA8 LOC115326903 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312002|UniProtKB=A0ACM8F8F3 A0ACM8F8F3 LOC115312002 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121838299|UniProtKB=A0ACM8G7M6 A0ACM8G7M6 LOC121838299 PTHR10334:SF517 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC121836327|UniProtKB=A0ACM8FYE0 A0ACM8FYE0 LOC121836327 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835317|UniProtKB=A0ACM8FT57 A0ACM8FT57 LOC121835317 PTHR24404:SF126 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120838910|UniProtKB=A0ACM8EKU2 A0ACM8EKU2 LOC120838910 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838003|UniProtKB=A0ACM8EJU4 A0ACM8EJU4 LOC120838003 PTHR15208:SF2 RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS CANCER ASSOCIATED SURFACE ANTIGEN RCAS1 ESTROGEN RECEPTOR-BINDING FRAGMENT- ASSOCIATED GENE 9 PROTEIN RECEPTOR-BINDING CANCER ANTIGEN EXPRESSED ON SISO CELLS protein-membrane adaptor activity#GO:0043495;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of exocytosis#GO:0017157;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;secretory vesicle#GO:0099503;intracellular vesicle#GO:0097708;vesicle#GO:0031982;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8033462|UniProtKB=A0ACM8DR27 A0ACM8DR27 LOC8033462 PTHR11475:SF106 OXIDASE/PEROXIDASE CURLY SU oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120846135|UniProtKB=A0ACM8F1K8 A0ACM8F1K8 LOC120846135 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8042919|UniProtKB=A0ACM8DYV7 A0ACM8DYV7 LOC8042919 PTHR11909:SF300 CASEIN KINASE-RELATED TAU-TUBULIN KINASE HOMOLOG ASATOR kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242 IXOSC|EnsemblGenome=LOC8036218|UniProtKB=A0ACM8DY52 A0ACM8DY52 LOC8036218 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121834780|UniProtKB=A0ACM8FR25 A0ACM8FR25 LOC121834780 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026542|UniProtKB=A0ACM8ELD8 A0ACM8ELD8 LOC8026542 PTHR11733:SF255 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED ENDOTHELIN-CONVERTING ENZYME metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115308313|UniProtKB=A0ACM8G149 A0ACM8G149 LOC115308313 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8042531|UniProtKB=A0ACM8G6A5 A0ACM8G6A5 LOC8042531 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121048433|UniProtKB=A0ACM8FI59 A0ACM8FI59 LOC121048433 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316926|UniProtKB=A0ACM8DX01 A0ACM8DX01 LOC115316926 PTHR11616:SF321 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT ACETYLCHOLINE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;glycine transport#GO:0015816;localization#GO:0051179;monoatomic cation transport#GO:0006812;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC8027640|UniProtKB=A0ACM8DSS9 A0ACM8DSS9 LOC8027640 PTHR22999:SF40 PX SERINE/THREONINE KINASE PXK PX DOMAIN-CONTAINING PROTEIN KINASE-LIKE PROTEIN biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115324888|UniProtKB=A0ACM8E563 A0ACM8E563 LOC115324888 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8026778|UniProtKB=A0ACM8EV92 A0ACM8EV92 LOC8026778 PTHR11532:SF96 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D-LIKE PROTEIN metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 IXOSC|EnsemblGenome=LOC115317697|UniProtKB=A0ACM8DXF3 A0ACM8DXF3 Wdr24 PTHR46200:SF1 GATOR COMPLEX PROTEIN WDR24 GATOR2 COMPLEX PROTEIN WDR24 regulation of macroautophagy#GO:0016241;cellular response to amino acid starvation#GO:0034198;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;positive regulation of macroautophagy#GO:0016239;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;positive regulation of TOR signaling#GO:0032008;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Seh1-associated complex#GO:0035859;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8026324|UniProtKB=A0ACM8DHM6 A0ACM8DHM6 LOC8026324 PTHR46628:SF2 PIRNA BIOGENESIS PROTEIN EXD1 PROTEIN EXD1 HOMOLOG protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115328617|UniProtKB=A0ACM8E8Y2 A0ACM8E8Y2 LOC115328617 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120850745|UniProtKB=A0ACM8FAN5 A0ACM8FAN5 LOC120850745 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033547|UniProtKB=A0ACM8DT45 A0ACM8DT45 Prosalpha2 PTHR11599:SF16 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-2 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;peptidase complex#GO:1905368;protein-containing complex#GO:0032991 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 IXOSC|EnsemblGenome=LOC121832855|UniProtKB=A0ACM8G057 A0ACM8G057 LOC121832855 PTHR10534:SF2 PYRIDOXAL KINASE PYRIDOXAL KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate biosynthetic process#GO:0090407;pyridine-containing compound metabolic process#GO:0072524;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 kinase#PC00137 Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine kinase#P03122;Vitamin B6 metabolism#P02787>Pyridoxal kinase#P03244;Pyridoxal phosphate salvage pathway#P02770>Pyridoxal kinase#P03121 IXOSC|EnsemblGenome=LOC115308457|UniProtKB=A0ACM8DML3 A0ACM8DML3 LOC115308457 PTHR14939:SF5 F-BOX ONLY PROTEIN 22 FIST C-DOMAIN DOMAIN-CONTAINING PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC8024077|UniProtKB=A0ACM8E8N1 A0ACM8E8N1 PTHR11034:SF40 N-MYC DOWNSTREAM REGULATED BCDNA.GH02439 cell communication#GO:0007154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8028475|UniProtKB=A0ACM8DMC9 A0ACM8DMC9 LOC8028475 PTHR13160:SF4 OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC OLIGOSACCHARYLTRANSFERASE COMPLEX SUBUNIT OSTC protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 biosynthetic process#GO:0009058;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;membrane protein complex#GO:0098796 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120850248|UniProtKB=A0ACM8FT58 A0ACM8FT58 LOC120850248 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845288|UniProtKB=A0ACM8F0F2 A0ACM8F0F2 LOC120845288 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040052|UniProtKB=A0ACM8DKG9 A0ACM8DKG9 LOC8040052 PTHR14677:SF46 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED ZINC FINGER AN1-TYPE CONTAINING 2A-RELATED establishment of protein localization to endoplasmic reticulum#GO:0072599;proteasomal protein catabolic process#GO:0010498;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting to ER#GO:0045047;ubiquitin-dependent protein catabolic process#GO:0006511;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;protein targeting#GO:0006605;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;localization#GO:0051179;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115331960|UniProtKB=A0ACM8F7Y1 A0ACM8F7Y1 LOC115331960 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115326026|UniProtKB=A0ACM8FZK2 A0ACM8FZK2 LOC115326026 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC115315792|UniProtKB=A0ACM8F727 A0ACM8F727 LOC115315792 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120844780|UniProtKB=A0ACM8EZ83 A0ACM8EZ83 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115318860|UniProtKB=A0ACM8ESA3 A0ACM8ESA3 LOC115318860 PTHR11544:SF148 COLD SHOCK DOMAIN CONTAINING PROTEINS LD37574P nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120838950|UniProtKB=A0ACM8G8Y4 A0ACM8G8Y4 LOC120838950 PTHR20963:SF56 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120836922|UniProtKB=A0ACM8EG53 A0ACM8EG53 LOC120836922 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC120837820|UniProtKB=A0ACM8EJ41 A0ACM8EJ41 LOC120837820 PTHR18934:SF229 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX30 ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;isomerase activity#GO:0016853;helicase activity#GO:0004386 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC120848871|UniProtKB=A0ACM8F6I2 A0ACM8F6I2 LOC120848871 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115321615|UniProtKB=A0ACM8E186 A0ACM8E186 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115330436|UniProtKB=A0ACM8ELA9 A0ACM8ELA9 LOC115330436 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848896|UniProtKB=A0ACM8FWP3 A0ACM8FWP3 LOC120848896 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120837050|UniProtKB=A0ACM8EG27 A0ACM8EG27 LOC120837050 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120836615|UniProtKB=A0ACM8EGF0 A0ACM8EGF0 LOC120836615 PTHR11075:SF54 PEPTIDE CHAIN RELEASE FACTOR LARGE RIBOSOMAL SUBUNIT PROTEIN ML62 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;translation factor activity#GO:0180051;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098 translation release factor#PC00225 IXOSC|EnsemblGenome=LOC115314916|UniProtKB=A0ACM8F2Q6 A0ACM8F2Q6 LOC115322945 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120838683|UniProtKB=A0ACM8FYY4 A0ACM8FYY4 LOC120838683 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8050403|UniProtKB=A0ACM8E311 A0ACM8E311 LOC8050403 PTHR11022:SF80 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LC-RELATED signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;peptidoglycan muralytic activity#GO:0061783 defense response#GO:0006952;response to external stimulus#GO:0009605;defense response to bacterium#GO:0042742;response to bacterium#GO:0009617;immune system process#GO:0002376;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8037430|UniProtKB=A0ACM8DSB6 A0ACM8DSB6 LOC8037430 PTHR23104:SF17 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8040489|UniProtKB=A0ACM8DQK0 A0ACM8DQK0 LOC8040489 PTHR45704:SF19 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE IXOSC|EnsemblGenome=LOC8043884|UniProtKB=A0ACM8DMN8 A0ACM8DMN8 LOC8043884 PTHR12801:SF164 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED EXONUCLEASE GOR-LIKE PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 exoribonuclease#PC00099;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115313488|UniProtKB=A0ACM8G5W2 A0ACM8G5W2 LOC115313488 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8053225|UniProtKB=A0ACM8DVV5 A0ACM8DVV5 LOC8053225 PTHR13328:SF7 NEGATIVE ELONGATION FACTOR A NELF-A NEGATIVE ELONGATION FACTOR A regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120845193|UniProtKB=A0ACM8EZN3 A0ACM8EZN3 LOC120845193 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025369|UniProtKB=A0ACM8DR14 A0ACM8DR14 LOC8025369 PTHR11552:SF233 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI02019P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8039860|UniProtKB=A0ACM8EQ67 A0ACM8EQ67 LOC8039860 PTHR13421:SF16 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 snRNA transcription#GO:0009301;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120845267|UniProtKB=A0ACM8F0G2 A0ACM8F0G2 LOC120845267 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8040639|UniProtKB=A0ACM8ESR0 A0ACM8ESR0 LOC8040639 PTHR45812:SF1 DNA POLYMERASE ZETA CATALYTIC SUBUNIT DNA POLYMERASE ZETA CATALYTIC SUBUNIT catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;DNA-directed DNA polymerase activity#GO:0003887 translesion synthesis#GO:0019985;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;DNA recombination#GO:0006310;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;DNA synthesis involved in DNA replication#GO:0090592;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;DNA polymerase complex#GO:0042575;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 IXOSC|EnsemblGenome=LOC115329558|UniProtKB=A0ACM8E9N4 A0ACM8E9N4 LOC115329558 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115314708|UniProtKB=A0ACM8FME5 A0ACM8FME5 LOC115314708 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8053640|UniProtKB=A0ACM8FDK2 A0ACM8FDK2 stumps PTHR16267:SF14 BANK1/PIK3AP1 FAMILY MEMBER STUMPS, ISOFORM E fibroblast growth factor receptor binding#GO:0005104;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;growth factor receptor binding#GO:0070851 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8029471|UniProtKB=A0ACM8E452 A0ACM8E452 LOC8029471 PTHR15117:SF24 ATAXIN 7 RELATED ATAXIN-7-LIKE PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 IXOSC|EnsemblGenome=LOC115328002|UniProtKB=A0ACM8FAD4 A0ACM8FAD4 LOC115328002 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8040751|UniProtKB=A0ACM8DH21 A0ACM8DH21 su(r) PTHR43073:SF5 DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)] nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265 nucleobase-containing compound metabolic process#GO:0006139;nucleobase catabolic process#GO:0046113;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;pyrimidine nucleobase catabolic process#GO:0006208;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;pyrimidine nucleobase metabolic process#GO:0006206;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 Pyrimidine Metabolism#P02771>Dihydrouracil Dehydrogenase#P03128 IXOSC|EnsemblGenome=LOC120837081|UniProtKB=A0ACM8EG56 A0ACM8EG56 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850860|UniProtKB=A0ACM8FBW3 A0ACM8FBW3 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8042291|UniProtKB=A0ACM8DKW6 A0ACM8DKW6 MetRS-m PTHR43326:SF8 METHIONYL-TRNA SYNTHETASE METHIONINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC115309581|UniProtKB=A0ACM8FQP1 A0ACM8FQP1 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8035086|UniProtKB=A0ACM8EQP2 A0ACM8EQP2 LOC8035086 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120838674|UniProtKB=A0ACM8EJP4 A0ACM8EJP4 LOC120838674 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8025742|UniProtKB=A0ACM8DS29 A0ACM8DS29 LOC8025742 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE response to stimulus#GO:0050896;protein folding#GO:0006457;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;protein refolding#GO:0042026;gene expression#GO:0010467;protein maturation#GO:0051604;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;response to heat#GO:0009408;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC115331630|UniProtKB=A0ACM8ED74 A0ACM8ED74 LOC115331630 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115308825|UniProtKB=A0ACM8EQD9 A0ACM8EQD9 LOC115308825 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8035283|UniProtKB=A0ACM8EER2 A0ACM8EER2 Dus3 PTHR45846:SF1 TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8030629|UniProtKB=A0ACM8DHA7 A0ACM8DHA7 Pcmt PTHR11579:SF0 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;O-methyltransferase activity#GO:0008171;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120846576|UniProtKB=A0ACM8F2G6 A0ACM8F2G6 LOC120846576 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115311063|UniProtKB=A0ACM8ESX9 A0ACM8ESX9 LOC115311063 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8027331|UniProtKB=A0ACM8FYE2 A0ACM8FYE2 LOC8027331 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120841528|UniProtKB=A0ACM8ERV4 A0ACM8ERV4 LOC120841528 PTHR45913:SF23 EPM2A-INTERACTING PROTEIN 1 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8032170|UniProtKB=A0ACM8DJ77 A0ACM8DJ77 PTHR22974:SF21 MIXED LINEAGE PROTEIN KINASE DUAL SPECIFICITY PROTEIN KINASE TTK catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of cell cycle#GO:0045786;negative regulation of mitotic sister chromatid segregation#GO:0033048;regulation of chromosome segregation#GO:0051983;chromosome segregation#GO:0007059;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of chromosome segregation#GO:0051985;meiotic cell cycle#GO:0051321;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;regulation of meiotic cell cycle#GO:0051445;negative regulation of cell cycle phase transition#GO:1901988;meiotic cell cycle process#GO:1903046;negative regulation of biological process#GO:0048519;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of reproductive process#GO:2000241;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of mitotic sister chromatid separation#GO:0010965;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;cell communication#GO:0007154;sexual reproduction#GO:0019953;negative regulation of chromosome organization#GO:2001251 condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8026327|UniProtKB=A0ACM8DMM9 A0ACM8DMM9 LOC8026327 PTHR33444:SF8 SI:DKEY-19B23.12-RELATED MARVEL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312253|UniProtKB=A0ACM8DRU5 A0ACM8DRU5 LOC115312253 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120839895|UniProtKB=A0ACM8ENX6 A0ACM8ENX6 LOC120839895 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120840628|UniProtKB=A0ACM8EP32 A0ACM8EP32 LOC120840628 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038030|UniProtKB=A0ACM8DRD9 A0ACM8DRD9 LOC8038030 PTHR12245:SF11 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN PROTEIN GUSTAVUS protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115311621|UniProtKB=A0ACM8DR20 A0ACM8DR20 LSm1 PTHR15588:SF8 LSM1 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;RNA decapping#GO:0110154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of RNA metabolic process#GO:0051254;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;intracellular anatomical structure#GO:0005622;P-body#GO:0000932;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8029274|UniProtKB=A0ACM8EGS5 A0ACM8EGS5 LOC8029274 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115321022|UniProtKB=A0ACM8FXM5 A0ACM8FXM5 LOC115321022 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8050439|UniProtKB=A0ACM8DLB1 A0ACM8DLB1 LOC8050439 PTHR45633:SF53 60 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL 60 KDA HEAT SHOCK PROTEIN HOMOLOG 1, MITOCHONDRIAL-RELATED binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;cellular localization#GO:0051641;cellular component organization#GO:0016043;apoptotic process#GO:0006915;response to stimulus#GO:0050896;mitochondrial transport#GO:0006839;response to topologically incorrect protein#GO:0035966;protein folding#GO:0006457;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;response to stress#GO:0006950;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;localization#GO:0051179;protein metabolic process#GO:0019538;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell death#GO:0008219;intracellular transport#GO:0046907;transport#GO:0006810;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;mitochondrial protein import pathway#GO:7770058 organelle membrane#GO:0031090;cytoplasm#GO:0005737;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC115308856|UniProtKB=A0ACM8EJH9 A0ACM8EJH9 LOC115308856 PTHR23098:SF16 AGAP001331-PA-RELATED GT1 DOMAIN-CONTAINING PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121836080|UniProtKB=A0ACM8FY15 A0ACM8FY15 LOC121836080 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8024233|UniProtKB=A0ACM8DNV2 A0ACM8DNV2 LOC8024233 PTHR23048:SF66 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN 2 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8031914|UniProtKB=A0ACM8DIW8 A0ACM8DIW8 Vps4 PTHR23074:SF83 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179;vacuole organization#GO:0007033;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;endosomal transport#GO:0016197;organelle organization#GO:0006996;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC121833303|UniProtKB=A0ACM8FL95 A0ACM8FL95 LOC121833303 PTHR46071:SF2 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING ANKYRIN REPEAT-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120841178|UniProtKB=A0ACM8ES51 A0ACM8ES51 LOC120841178 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8031793|UniProtKB=A0ACM8DIQ8 A0ACM8DIQ8 LOC8031793 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121833276|UniProtKB=A0ACM8FJV2 A0ACM8FJV2 LOC121833276 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323559|UniProtKB=A0ACM8E344 A0ACM8E344 LOC115323559 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120848861|UniProtKB=A0ACM8F5P8 A0ACM8F5P8 LOC120848861 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8037388|UniProtKB=A0ACM8ECI0 A0ACM8ECI0 LOC8037388 PTHR22100:SF13 WINGS APART-LIKE PROTEIN HOMOLOG WINGS APART-LIKE PROTEIN HOMOLOG IXOSC|EnsemblGenome=LOC120835954|UniProtKB=A0ACM8EH77 A0ACM8EH77 LOC120835954 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040215|UniProtKB=A0ACM8DT92 A0ACM8DT92 LOC8040215 PTHR12433:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC121834194|UniProtKB=A0ACM8FPF4 A0ACM8FPF4 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8053359|UniProtKB=A0ACM8DLS6 A0ACM8DLS6 LOC8053359 PTHR43461:SF1 TRANSMEMBRANE PROTEIN 256 TRANSMEMBRANE PROTEIN 256 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8027171|UniProtKB=A0ACM8E0G5 A0ACM8E0G5 LOC8027171 PTHR12114:SF4 PARVIN GH23568P actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;actin filament-based process#GO:0030029;cellular process#GO:0009987 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin and actin related protein#PC00039;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC120842684|UniProtKB=A0ACM8EU94 A0ACM8EU94 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120838270|UniProtKB=A0ACM8EIW2 A0ACM8EIW2 LOC120838270 PTHR23281:SF18 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;biological regulation#GO:0065007;regulation of anatomical structure morphogenesis#GO:0022603;regulation of localization#GO:0032879;regulation of transport#GO:0051049 adherens junction#GO:0005912;cell junction#GO:0030054;membraneless organelle#GO:0043228;apical part of cell#GO:0045177;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;filopodium#GO:0030175;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC120837464|UniProtKB=A0ACM8EHJ7 A0ACM8EHJ7 LOC120837464 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8034749|UniProtKB=A0ACM8E735 A0ACM8E735 LOC8034749 PTHR24056:SF599 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 11A-RELATED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115313269|UniProtKB=A0ACM8DSM1 A0ACM8DSM1 LOC115313269 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120844772|UniProtKB=A0ACM8FK07 A0ACM8FK07 ND-39 PTHR12126:SF11 NADH-UBIQUINONE OXIDOREDUCTASE 39 KDA SUBUNIT-RELATED NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 9, MITOCHONDRIAL protein-containing complex binding#GO:0044877;binding#GO:0005488 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115315851|UniProtKB=A0ACM8DVX9 A0ACM8DVX9 LOC115315851 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8033429|UniProtKB=A0ACM8DQG6 A0ACM8DQG6 LOC8033429 PTHR23254:SF17 EIF4G DOMAIN PROTEIN MIF4G DOMAIN-CONTAINING PROTEIN translation regulator activity#GO:0045182 regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120848162|UniProtKB=A0ACM8FPP7 A0ACM8FPP7 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121837614|UniProtKB=A0ACM8G5K8 A0ACM8G5K8 LOC121837614 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839987|UniProtKB=A0ACM8EMZ7 A0ACM8EMZ7 LOC120839987 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8040357|UniProtKB=A0ACM8DSG0 A0ACM8DSG0 LOC8040357 PTHR14897:SF5 WD REPEAT AND COILED-COIL-CONTAINING PROTEIN WD REPEAT AND COILED-COIL-CONTAINING PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;protein binding#GO:0005515 IXOSC|EnsemblGenome=LOC115310757|UniProtKB=A0ACM8FJ27 A0ACM8FJ27 LOC115310757 PTHR10334:SF615 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC115308396|UniProtKB=A0ACM8DMD3 A0ACM8DMD3 LOC115308396 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8036059|UniProtKB=A0ACM8DJW4 A0ACM8DJW4 LOC8036059 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC121837035|UniProtKB=A0ACM8G2G1 A0ACM8G2G1 LOC121837035 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331718|UniProtKB=A0ACM8DK37 A0ACM8DK37 LOC115331718 PTHR12606:SF141 SENTRIN/SUMO-SPECIFIC PROTEASE GH15225P-RELATED catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 protease#PC00190 IXOSC|EnsemblGenome=LOC121833639|UniProtKB=A0ACM8FLQ6 A0ACM8FLQ6 LOC121833639 PTHR23199:SF19 NEUROTROPHIN 1-RELATED SPAETZLE DOMAIN-CONTAINING PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 innate immune response#GO:0045087;multicellular organism development#GO:0007275;defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;response to external stimulus#GO:0009605;developmental process#GO:0032502;multicellular organismal process#GO:0032501;defense response to other organism#GO:0098542;nervous system development#GO:0007399;response to other organism#GO:0051707;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;central nervous system development#GO:0007417;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;anatomical structure morphogenesis#GO:0009653 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC121835263|UniProtKB=A0ACM8FT25 A0ACM8FT25 LOC121835263 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120842026|UniProtKB=A0ACM8EU01 A0ACM8EU01 LOC120842026 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC121837485|UniProtKB=A0ACM8G3N1 A0ACM8G3N1 LOC121837485 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC115312844|UniProtKB=A0ACM8EK90 A0ACM8EK90 LOC115312844 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840444|UniProtKB=A0ACM8EP25 A0ACM8EP25 LOC120840444 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8029025|UniProtKB=A0ACM8DHH1 A0ACM8DHH1 EMC5 PTHR21181:SF7 ER membrane protein complex subunit 5-related ER MEMBRANE PROTEIN COMPLEX SUBUNIT 5 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;protein localization to organelle#GO:0033365 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546 IXOSC|EnsemblGenome=LOC8030143|UniProtKB=A0ACM8FWZ5 A0ACM8FWZ5 LOC8030143 PTHR46480:SF1 F20B24.22 VOLTAGE-GATED HYDROGEN CHANNEL 1 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;voltage-gated monoatomic cation channel activity#GO:0022843;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8032079|UniProtKB=A0ACM8DJ62 A0ACM8DJ62 DCAF12 PTHR19860:SF16 DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED DDB1- AND CUL4-ASSOCIATED FACTOR 12 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 IXOSC|EnsemblGenome=LOC115317479|UniProtKB=A0ACM8DX17 A0ACM8DX17 LOC115317479 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8037666|UniProtKB=A0ACM8DM64 A0ACM8DM64 NiPp1 PTHR23308:SF74 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE 1 phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;protein serine/threonine phosphatase inhibitor activity#GO:0004865 generation of neurons#GO:0048699;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;positive regulation of signaling#GO:0023056;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;positive regulation of BMP signaling pathway#GO:0030513;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of BMP signaling pathway#GO:0030510;axon guidance#GO:0007411;axon development#GO:0061564;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501 organelle lumen#GO:0043233;nuclear speck#GO:0016607;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 RNA splicing factor#PC00148 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 IXOSC|EnsemblGenome=LOC120841476|UniProtKB=A0ACM8FF05 A0ACM8FF05 LOC120841476 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121045970|UniProtKB=A0ACM8G8V3 A0ACM8G8V3 LOC121045970 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839924|UniProtKB=A0ACM8ENZ3 A0ACM8ENZ3 LOC120839924 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121835783|UniProtKB=A0ACM8FVV2 A0ACM8FVV2 LOC8051373 PTHR13340:SF2 GATA ZINC FINGER DOMAIN-CONTAINING GATA ZINC FINGER DOMAIN-CONTAINING PROTEIN 1 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115324538|UniProtKB=A0ACM8E5B8 A0ACM8E5B8 LOC115324538 PTHR11214:SF379 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8029599|UniProtKB=A0ACM8DVF6 A0ACM8DVF6 LOC8029599 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;antioxidant activity#GO:0016209;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8025860|UniProtKB=A0ACM8F3U4 A0ACM8F3U4 LOC8025860 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121835712|UniProtKB=A0ACM8FVI5 A0ACM8FVI5 LOC121835712 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8039345|UniProtKB=A0ACM8E7V0 A0ACM8E7V0 LOC8039345 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8029823|UniProtKB=A0ACM8FNV8 A0ACM8FNV8 PTHR11590:SF69 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 immune system process#GO:0002376;response to external stimulus#GO:0009605;defense response#GO:0006952;innate immune response#GO:0045087;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to other organism#GO:0098542 transferase#PC00220 IXOSC|EnsemblGenome=LOC115324315|UniProtKB=A0ACM8EGS8 A0ACM8EGS8 LOC115324315 PTHR46393:SF7 SUSHI DOMAIN-CONTAINING PROTEIN C3_C5 CONVERTASE IXOSC|EnsemblGenome=LOC8033456|UniProtKB=A0ACM8DNT8 A0ACM8DNT8 LOC8033456 PTHR13817:SF155 TITIN IG-LIKE AND FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN C25G4.10 structural protein#PC00211 IXOSC|EnsemblGenome=LOC115312018|UniProtKB=A0ACM8EP38 A0ACM8EP38 LOC115312018 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120847393|UniProtKB=A0ACM8F350 A0ACM8F350 LOC120847393 PTHR10501:SF13 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;U1 snRNP#GO:0005685;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 mRNA splicing#P00058>U2#P01478;mRNA splicing#P00058>U1#P01479 IXOSC|EnsemblGenome=LOC8024062|UniProtKB=A0ACM8E4S0 A0ACM8E4S0 LOC8024062 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996 IXOSC|EnsemblGenome=LOC8043070|UniProtKB=A0ACM8E771 A0ACM8E771 LOC8043070 PTHR12801:SF158 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 4 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;DNA catabolic process#GO:0006308;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 exoribonuclease#PC00099;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8038310|UniProtKB=A0ACM8E593 A0ACM8E593 PTHR11008:SF9 PROTEIN TAKEOUT-LIKE PROTEIN FI04421P IXOSC|EnsemblGenome=LOC121838196|UniProtKB=A0ACM8G6S0 A0ACM8G6S0 LOC121838196 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034440|UniProtKB=A0ACM8DTJ1 A0ACM8DTJ1 LOC8034440 PTHR24089:SF705 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A16 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115322389|UniProtKB=A0ACM8FL98 A0ACM8FL98 LOC115322389 PTHR12843:SF5 PROTEIN-LYSINE N-METHYLTRANSFERASE METTL10 EEF1A LYSINE METHYLTRANSFERASE 2 lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121045974|UniProtKB=A0ACM8FQP7 A0ACM8FQP7 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115318534|UniProtKB=A0ACM8DY69 A0ACM8DY69 LOC115318534 PTHR12233:SF2 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26C intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8035709|UniProtKB=A0ACM8DUJ1 A0ACM8DUJ1 LOC8035709 PTHR11224:SF10 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120840471|UniProtKB=A0ACM8FEE8 A0ACM8FEE8 LOC120840471 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844492|UniProtKB=A0ACM8EZW5 A0ACM8EZW5 LOC120844492 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8035700|UniProtKB=A0ACM8E6J9 A0ACM8E6J9 didum PTHR13140:SF880 MYOSIN DILUTE CLASS UNCONVENTIONAL MYOSIN, ISOFORM C cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC121048452|UniProtKB=A0ACM8FJC5 A0ACM8FJC5 LOC121048452 PTHR23292:SF6 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16602P1-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;zinc ion binding#GO:0008270;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115332272|UniProtKB=A0ACM8EDK8 A0ACM8EDK8 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120848823|UniProtKB=A0ACM8G4Z8 A0ACM8G4Z8 LOC120848823 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8052553|UniProtKB=A0ACM8G7L4 A0ACM8G7L4 LOC8052553 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8025927|UniProtKB=A0ACM8EA89 A0ACM8EA89 LOC8025927 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8043565|UniProtKB=A0ACM8DWB9 A0ACM8DWB9 LOC8043565 PTHR43975:SF6 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8031120|UniProtKB=A0ACM8DHY6 A0ACM8DHY6 LOC8031120 PTHR35841:SF1 PHOSPHONATES-BINDING PERIPLASMIC PROTEIN PHOSPHATE ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN IXOSC|EnsemblGenome=LOC121832864|UniProtKB=A0ACM8FJV8 A0ACM8FJV8 LOC121832864 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8032054|UniProtKB=A0ACM8F5C9 A0ACM8F5C9 LOC8032054 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8039707|UniProtKB=A0ACM8FJ22 A0ACM8FJ22 LOC8039707 PTHR10071:SF337 TRANSCRIPTION FACTOR GATA FAMILY MEMBER BOX A-BINDING FACTOR-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell fate commitment#GO:0045165;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of metabolic process#GO:0009892;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121837706|UniProtKB=A0ACM8G650 A0ACM8G650 LOC121837706 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120841262|UniProtKB=A0ACM8ERF8 A0ACM8ERF8 LOC120841262 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8041686|UniProtKB=A0ACM8E7H7 A0ACM8E7H7 LOC8041686 PTHR31019:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 14 SMALL INTEGRAL MEMBRANE PROTEIN 14 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC8025647|UniProtKB=A0ACM8F291 A0ACM8F291 LOC8025647 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC121045487|UniProtKB=A0ACM8FPA8 A0ACM8FPA8 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8039378|UniProtKB=A0ACM8E1W4 A0ACM8E1W4 LOC8039378 PTHR24388:SF54 ZINC FINGER PROTEIN PROTEIN ESCARGOT DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8040201|UniProtKB=A0ACM8FK17 A0ACM8FK17 LOC8040201 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC120844894|UniProtKB=A0ACM8F0Z3 A0ACM8F0Z3 LOC120844894 PTHR37162:SF13 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836182|UniProtKB=A0ACM8FYR0 A0ACM8FYR0 LOC121836182 PTHR10177:SF347 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914 mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227 kinase activator#PC00138 p53 pathway#P00059>Cyclin B#P04614;Cell cycle#P00013>Cyclin B#P00486 IXOSC|EnsemblGenome=LOC115316623|UniProtKB=A0ACM8F7V3 A0ACM8F7V3 LOC115316623 PTHR23346:SF19 TRANSLATIONAL ACTIVATOR GCN1-RELATED PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29 protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8030632|UniProtKB=A0ACM8FP14 A0ACM8FP14 IFT43 PTHR33724:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 43 HOMOLOG cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;transport#GO:0006810;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;cilium organization#GO:0044782;microtubule-based transport#GO:0099111 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;intraciliary transport particle A#GO:0030991 IXOSC|EnsemblGenome=LOC8026231|UniProtKB=A0ACM8F8V9 A0ACM8F8V9 LOC8026231 PTHR13743:SF165 BEIGE/BEACH-RELATED NEUROBEACHIN-LIKE PROTEIN 1 ISOFORM X1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8039884|UniProtKB=A0ACM8FPQ8 A0ACM8FPQ8 PTHR12736:SF21 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 2 regulation of cellular process#GO:0050794;regulation of cellular response to alcohol#GO:1905957;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of response to alcohol#GO:1901419;regulation of response to stimulus#GO:0048583;regulation of abscisic acid-activated signaling pathway#GO:0009787;regulation of signaling#GO:0023051 IXOSC|EnsemblGenome=LOC120836376|UniProtKB=A0ACM8EEI9 A0ACM8EEI9 LOC120836376 PTHR23003:SF53 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE-ARGININE PROTEIN 55-LIKE PROTEIN mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8042781|UniProtKB=A0ACM8FBT6 A0ACM8FBT6 LOC8042781 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid localization#GO:0010876;localization#GO:0051179;ceramide metabolic process#GO:0006672;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid metabolic process#GO:0006629;transport#GO:0006810;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;establishment of localization#GO:0051234 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8039539|UniProtKB=A0ACM8DPX5 A0ACM8DPX5 Rab8 PTHR47980:SF101 LD44762P IP08727P-RELATED export from cell#GO:0140352;endocytic recycling#GO:0032456;secretion by cell#GO:0032940;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endosomal transport#GO:0016197;exocytosis#GO:0006887;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;clathrin-coated vesicle#GO:0030136;Golgi-associated vesicle#GO:0005798;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network transport vesicle#GO:0030140;endosome#GO:0005768;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115332725|UniProtKB=A0ACM8FA84 A0ACM8FA84 PTHR10283:SF136 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2-LIKE ISOFORM X1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC115325946|UniProtKB=A0ACM8E693 A0ACM8E693 Rpp20 PTHR15314:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P20 RIBONUCLEASE P PROTEIN SUBUNIT P20 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 endoribonuclease#PC00094;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115308597|UniProtKB=A0ACM8DMN9 A0ACM8DMN9 LOC115308597 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115310429|UniProtKB=A0ACM8DPY1 A0ACM8DPY1 LOC115310429 PTHR22748:SF6 AP ENDONUCLEASE DNA REPAIR NUCLEASE_REDOX REGULATOR APEX1 DNA exonuclease activity#GO:0004529;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;exonuclease activity#GO:0004527;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;DNA endonuclease activity#GO:0004520;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;hydrolase activity#GO:0016787 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 IXOSC|EnsemblGenome=LOC120844580|UniProtKB=A0ACM8EZ29 A0ACM8EZ29 LOC120844580 PTHR19282:SF570 TETRASPANIN TETRASPANIN TSPA-RELATED scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8035199|UniProtKB=A0ACM8FX91 A0ACM8FX91 LOC8035199 PTHR23048:SF64 MYOSIN LIGHT CHAIN 1, 3 TROPONIN C actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8051929|UniProtKB=A0ACM8ETI5 A0ACM8ETI5 LOC8051929 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED IXOSC|EnsemblGenome=LOC121836526|UniProtKB=A0ACM8FYI5 A0ACM8FYI5 LOC121836526 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037016|UniProtKB=A0ACM8EZH3 A0ACM8EZH3 LOC8037016 PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178 transporter#PC00227 IXOSC|EnsemblGenome=LOC115319187|UniProtKB=A0ACM8FXX0 A0ACM8FXX0 LOC115319187 PTHR12243:SF74 MADF DOMAIN TRANSCRIPTION FACTOR MYB_SANT-LIKE TRANSCRIPTION FACTOR regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115312544|UniProtKB=A0ACM8EI82 A0ACM8EI82 LOC115312544 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE protein metabolic process#GO:0019538;protein refolding#GO:0042026;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC8027006|UniProtKB=A0ACM8EAJ3 A0ACM8EAJ3 LOC8027006 PTHR24346:SF74 MAP/MICROTUBULE AFFINITY-REGULATING KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120840284|UniProtKB=A0ACM8ENQ6 A0ACM8ENQ6 LOC120840284 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027401|UniProtKB=A0ACM8E2Z6 A0ACM8E2Z6 LOC8027401 PTHR48037:SF1 ATPASE E1 RRM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308756|UniProtKB=A0ACM8EGJ5 A0ACM8EGJ5 LOC115308756 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120836255|UniProtKB=A0ACM8F5E5 A0ACM8F5E5 LOC120836255 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8043909|UniProtKB=A0ACM8E9K5 A0ACM8E9K5 Ccdc85 PTHR13546:SF15 RE60986P CCDC85 IXOSC|EnsemblGenome=LOC121837791|UniProtKB=A0ACM8G4T6 A0ACM8G4T6 LOC121837791 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8043037|UniProtKB=A0ACM8F745 A0ACM8F745 LOC8043037 PTHR16120:SF0 AP-5 COMPLEX SUBUNIT SIGMA-1 AP-5 COMPLEX SUBUNIT SIGMA-1 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;cytosol#GO:0005829;lytic vacuole#GO:0000323;AP-type membrane coat adaptor complex#GO:0030119 IXOSC|EnsemblGenome=LOC8030963|UniProtKB=A0ACM8DHS9 A0ACM8DHS9 LOC8030963 PTHR12560:SF58 LONGEVITY ASSURANCE FACTOR 1 LAG1 CERAMIDE SYNTHASE 1 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;ceramide metabolic process#GO:0006672 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120837067|UniProtKB=A0ACM8FU61 A0ACM8FU61 LOC120837067 PTHR10291:SF51 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 isoprenoid metabolic process#GO:0006720;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8023901|UniProtKB=A0ACM8E9C3 A0ACM8E9C3 mRpL4 PTHR10746:SF18 50S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;post-transcriptional regulation of gene expression#GO:0010608;regulation of cell communication#GO:0010646;positive regulation of Notch signaling pathway#GO:0045747;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115325771|UniProtKB=A0ACM8E560 A0ACM8E560 LOC115325771 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324669|UniProtKB=A0ACM8F576 A0ACM8F576 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8050653|UniProtKB=A0ACM8E9Q3 A0ACM8E9Q3 LOC8050653 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8038337|UniProtKB=A0ACM8DV85 A0ACM8DV85 Bka PTHR12416:SF2 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN FCF1 HOMOLOG rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115324851|UniProtKB=A0ACM8E4F1 A0ACM8E4F1 LOC115324851 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC115322218|UniProtKB=A0ACM8G1S0 A0ACM8G1S0 LOC115322218 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115333025|UniProtKB=A0ACM8EDY6 A0ACM8EDY6 LOC115333025 PTHR16105:SF2 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING PROTEIN 41 IXOSC|EnsemblGenome=LOC8024770|UniProtKB=A0ACM8E9V1 A0ACM8E9V1 Orc4 PTHR12087:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 ORIGIN RECOGNITION COMPLEX SUBUNIT 4 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;molecular adaptor activity#GO:0060090;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear origin of replication recognition complex#GO:0005664;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 IXOSC|EnsemblGenome=LOC8041520|UniProtKB=A0ACM8FRF6 A0ACM8FRF6 LOC8041520 PTHR11306:SF0 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED LP08842P-RELATED binding#GO:0005488;sterol binding#GO:0032934;lipid binding#GO:0008289;steroid binding#GO:0005496 lipid localization#GO:0010876;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;sterol transport#GO:0015918;organic hydroxy compound transport#GO:0015850;macromolecule localization#GO:0033036;lipid transport#GO:0006869 IXOSC|EnsemblGenome=LOC8033104|UniProtKB=A0ACM8FF39 A0ACM8FF39 LOC8033104 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC121837328|UniProtKB=A0ACM8G375 A0ACM8G375 LOC121837328 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115320888|UniProtKB=A0ACM8E1F9 A0ACM8E1F9 LOC115320888 PTHR13377:SF3 PLACENTAL PROTEIN 6 TRANSMEMBRANE PROTEIN 115 transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;Golgi cisterna#GO:0031985;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;Golgi stack#GO:0005795;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791 vesicle coat protein#PC00235;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8050676|UniProtKB=A0ACM8DLP8 A0ACM8DLP8 LOC8050676 PTHR46830:SF2 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220 IXOSC|EnsemblGenome=LOC8031140|UniProtKB=A0ACM8DHZ5 A0ACM8DHZ5 LOC8031140 PTHR45774:SF3 BTB/POZ DOMAIN-CONTAINING BTB (POZ) DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN-RELATED multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121835414|UniProtKB=A0ACM8FTY8 A0ACM8FTY8 LOC121835414 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316004|UniProtKB=A0ACM8DVG0 A0ACM8DVG0 LOC115316004 PTHR46612:SF1 XYLOSIDE XYLOSYLTRANSFERASE 1 XYLOSIDE XYLOSYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220 IXOSC|EnsemblGenome=LOC115331815|UniProtKB=A0ACM8ED06 A0ACM8ED06 LOC115331815 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834454|UniProtKB=A0ACM8FQA6 A0ACM8FQA6 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033608|UniProtKB=A0ACM8DY62 A0ACM8DY62 LOC8033608 PTHR12473:SF8 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED UBIQUITIN CARBOXYL-TERMINAL HYDROLASE MINDY-4-RELATED IXOSC|EnsemblGenome=LOC8030014|UniProtKB=A0ACM8E6B3 A0ACM8E6B3 LOC8030014 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC8034888|UniProtKB=A0ACM8DJM4 A0ACM8DJM4 Aps PTHR12629:SF0 DIPHOSPHOINOSITOL POLYPHOSPHATE PHOSPHOHYDROLASE DIPHOSPHOINOSITOL-POLYPHOSPHATE DIPHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;alcohol metabolic process#GO:0006066;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;nucleoside phosphate metabolic process#GO:0006753;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8052184|UniProtKB=A0ACM8G3Z1 A0ACM8G3Z1 LOC8052184 PTHR47219:SF27 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE TBC1 DOMAIN FAMILY MEMBER 9B protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;molecular function activator activity#GO:0140677;binding#GO:0005488;enzyme binding#GO:0019899;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC115319271|UniProtKB=A0ACM8F052 A0ACM8F052 LOC115319271 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC121837607|UniProtKB=A0ACM8G484 A0ACM8G484 LOC121837607 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041799|UniProtKB=A0ACM8EVY9 A0ACM8EVY9 LOC8041799 PTHR19969:SF14 SH2-SH3 ADAPTOR PROTEIN-RELATED SH2_SH3 ADAPTER PROTEIN DREADLOCKS signaling adaptor activity#GO:0035591;protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;positive regulation of macromolecule metabolic process#GO:0010604;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;positive regulation of apoptotic process#GO:0043065;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;response to stimulus#GO:0050896;positive regulation of programmed cell death#GO:0043068;cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of signaling#GO:0023056;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular process#GO:0048522;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;cell migration#GO:0016477;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of intrinsic apoptotic signaling pathway#GO:2001242;positive regulation of signal transduction#GO:0009967;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of apoptotic signaling pathway#GO:2001233;response to endoplasmic reticulum stress#GO:0034976;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8024488|UniProtKB=A0ACM8E9T3 A0ACM8E9T3 casp PTHR23322:SF107 FAS-ASSOCIATED PROTEIN CASPAR, ISOFORM A protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 FAS signaling pathway#P00020>FAF1#P00609 IXOSC|EnsemblGenome=LOC115331219|UniProtKB=A0ACM8ECB6 A0ACM8ECB6 LOC115331219 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8044119|UniProtKB=A0ACM8DL78 A0ACM8DL78 LOC8044119 PTHR19282:SF431 TETRASPANIN TETRASPANIN 26A, ISOFORM B plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120843900|UniProtKB=A0ACM8EX65 A0ACM8EX65 LOC120843900 PTHR13558:SF1 TRANSMEMBRANE PROTEIN 134 TRANSMEMBRANE PROTEIN 134 IXOSC|EnsemblGenome=LOC8050576|UniProtKB=A0ACM8FYQ3 A0ACM8FYQ3 LOC8050576 PTHR23023:SF317 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115328147|UniProtKB=A0ACM8EZG1 A0ACM8EZG1 LOC115328147 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120836353|UniProtKB=A0ACM8EEU5 A0ACM8EEU5 LOC120836353 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8042897|UniProtKB=A0ACM8EA59 A0ACM8EA59 LOC8042897 PTHR31548:SF1 CLARIN LD47387P IXOSC|EnsemblGenome=LOC8040986|UniProtKB=A0ACM8EZ42 A0ACM8EZ42 LOC8040986 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115317863|UniProtKB=A0ACM8EFK6 A0ACM8EFK6 LOC115317863 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829 polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC8027313|UniProtKB=A0ACM8DTC0 A0ACM8DTC0 LOC8027313 PTHR10026:SF8 CYCLIN CYCLIN-H cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 kinase modulator#PC00140;kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8053604|UniProtKB=A0ACM8E8F2 A0ACM8E8F2 LOC8053604 PTHR12974:SF36 PRION-LIKE- Q/N-RICH -DOMAIN-BEARING PROTEIN PROTEIN 44 POLYNUCLEOTIDE ADENYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of RNA catabolic process#GO:1902369;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;positive regulation of biosynthetic process#GO:0009891;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of RNA metabolic process#GO:0051253;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;mRNA stabilization#GO:0048255;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;RNA stabilization#GO:0043489;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892 IXOSC|EnsemblGenome=LOC115330058|UniProtKB=A0ACM8EBQ2 A0ACM8EBQ2 LOC115330058 PTHR11060:SF0 PROTEIN MEMO1 PROTEIN MEMO1 IXOSC|EnsemblGenome=LOC8036777|UniProtKB=A0ACM8FDN8 A0ACM8FDN8 LOC8036777 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120840512|UniProtKB=A0ACM8EPQ3 A0ACM8EPQ3 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121046181|UniProtKB=A0ACM8FDI2 A0ACM8FDI2 LOC121046181 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041400|UniProtKB=A0ACM8DKL9 A0ACM8DKL9 Rnmt PTHR12189:SF2 MRNA GUANINE-7- METHYLTRANSFERASE MRNA CAP GUANINE-N(7) METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8044065|UniProtKB=A0ACM8DL74 A0ACM8DL74 l(3)07882 PTHR23183:SF0 NOP14 NUCLEOLAR PROTEIN 14 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8051594|UniProtKB=A0ACM8DVJ9 A0ACM8DVJ9 Prosbeta1 PTHR32194:SF0 METALLOPROTEASE TLDD ATP-DEPENDENT PROTEASE SUBUNIT HSLV macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121047177|UniProtKB=A0ACM8FMP5 A0ACM8FMP5 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276 IXOSC|EnsemblGenome=LOC120840434|UniProtKB=A0ACM8EQ45 A0ACM8EQ45 LOC120840434 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;chromosome#GO:0005694;chromatin#GO:0000785;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121834685|UniProtKB=A0ACM8FQG4 A0ACM8FQG4 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115318419|UniProtKB=A0ACM8F7A9 A0ACM8F7A9 LOC115318419 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846339|UniProtKB=A0ACM8FHB3 A0ACM8FHB3 LOC120846339 PTHR45632:SF36 LD33804P RING ZINC FINGER-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8041494|UniProtKB=A0ACM8DXR2 A0ACM8DXR2 LOC8041494 PTHR12972:SF0 DOWNSTREAM NEIGHBOR OF SON PROTEIN DOWNSTREAM NEIGHBOR OF SON cellular process#GO:0009987;DNA replication#GO:0006260;cell cycle process#GO:0022402;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8042770|UniProtKB=A0ACM8DYA4 A0ACM8DYA4 LOC8042770 PTHR43788:SF20 DNA2/NAM7 HELICASE FAMILY MEMBER DNA-BINDING PROTEIN SMUBP-2 macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stress#GO:0006950 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120844826|UniProtKB=A0ACM8G2W3 A0ACM8G2W3 LOC120844826 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328957|UniProtKB=A0ACM8EP40 A0ACM8EP40 LOC115328957 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8027243|UniProtKB=A0ACM8FU16 A0ACM8FU16 rdgC PTHR45668:SF3 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE RDGC protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC120842748|UniProtKB=A0ACM8EUC1 A0ACM8EUC1 LOC120842748 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8043177|UniProtKB=A0ACM8E4P1 A0ACM8E4P1 drosha PTHR11207:SF37 RIBONUCLEASE III RIBONUCLEASE 3 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;primary miRNA processing#GO:0031053;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 endoribonuclease#PC00094;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121833916|UniProtKB=A0ACM8FNK9 A0ACM8FNK9 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310574|UniProtKB=A0ACM8FYY8 A0ACM8FYY8 LOC115310574 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316298|UniProtKB=A0ACM8DWH5 A0ACM8DWH5 LOC115316298 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8030043|UniProtKB=A0ACM8DJ58 A0ACM8DJ58 LOC8030043 PTHR18945:SF824 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR BETA 3 (DBETA3) SUBUNIT transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;transmembrane transport#GO:0055085;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;transport#GO:0006810;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC115330860|UniProtKB=A0ACM8ESW5 A0ACM8ESW5 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839662|UniProtKB=A0ACM8EM71 A0ACM8EM71 LOC120839662 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038695|UniProtKB=A0ACM8FFJ1 A0ACM8FFJ1 mRpL17 PTHR14413:SF24 RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN BL17M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8030507|UniProtKB=A0ACM8FYS0 A0ACM8FYS0 LOC8030507 PTHR10814:SF21 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSCRIPTION FACTOR UNC-37 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 IXOSC|EnsemblGenome=LOC115323524|UniProtKB=A0ACM8E339 A0ACM8E339 LOC115323524 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115330380|UniProtKB=A0ACM8EEY4 A0ACM8EEY4 LOC115330380 PTHR24381:SF470 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8032821|UniProtKB=A0ACM8EM20 A0ACM8EM20 LOC8032821 PTHR47023:SF1 SEX PEPTIDE RECEPTOR SEX PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8031753|UniProtKB=A0ACM8DU42 A0ACM8DU42 LOC8031753 PTHR11559:SF370 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE-RELATED esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 IXOSC|EnsemblGenome=LOC120836180|UniProtKB=A0ACM8FFT7 A0ACM8FFT7 PTHR20884:SF8 GDP-D-GLUCOSE PHOSPHORYLASE 1 GDP-D-GLUCOSE PHOSPHORYLASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;glucose metabolic process#GO:0006006;response to stress#GO:0006950;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;carbohydrate metabolic process#GO:0005975 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8030178|UniProtKB=A0ACM8EUW9 A0ACM8EUW9 LOC8030178 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115331676|UniProtKB=A0ACM8ECT5 A0ACM8ECT5 LOC115331676 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120841631|UniProtKB=A0ACM8FJS2 A0ACM8FJS2 LOC120841631 PTHR24256:SF470 TRYPTASE-RELATED SERINE PROTEASE 33 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8031684|UniProtKB=A0ACM8EMA0 A0ACM8EMA0 LOC8031684 PTHR45632:SF36 LD33804P RING ZINC FINGER-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8050853|UniProtKB=A0ACM8E7J6 A0ACM8E7J6 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8051730|UniProtKB=A0ACM8DY89 A0ACM8DY89 LOC8051730 PTHR11686:SF77 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987;sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8040021|UniProtKB=A0ACM8E1F5 A0ACM8E1F5 LOC8040021 PTHR11785:SF512 AMINO ACID TRANSPORTER B(0,+)-TYPE AMINO ACID TRANSPORTER 1 L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8036193|UniProtKB=A0ACM8DU52 A0ACM8DU52 LOC8036193 PTHR11003:SF366 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 18 voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8027267|UniProtKB=A0ACM8E2J1 A0ACM8E2J1 LOC8027267 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8052137|UniProtKB=A0ACM8E634 A0ACM8E634 LOC8052137 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121833167|UniProtKB=A0ACM8FJH5 A0ACM8FJH5 LOC121833167 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115332244|UniProtKB=A0ACM8EDB9 A0ACM8EDB9 LOC115332244 PTHR15092:SF44 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PARN hydrolase activity#GO:0016787;RNA binding#GO:0003723;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;nucleic acid binding#GO:0003676;binding#GO:0005488;3'-5'-RNA exonuclease activity#GO:0000175;RNA nuclease activity#GO:0004540;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA processing#GO:0006396;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC120843204|UniProtKB=A0ACM8EVK6 A0ACM8EVK6 LOC120843204 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316122|UniProtKB=A0ACM8DW65 A0ACM8DW65 LOC115316122 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8041902|UniProtKB=A0ACM8DR89 A0ACM8DR89 LOC8041902 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8034996|UniProtKB=A0ACM8FCI2 A0ACM8FCI2 LOC8034996 PTHR11848:SF263 TGF-BETA FAMILY PROTEIN DECAPENTAPLEGIC molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 DPP signaling pathway#P06213>DPP#P06285;DPP-SCW signaling pathway#P06212>DPP full length#P06273;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;TGF-beta signaling pathway#P00052>TGFbeta#P01286;DPP-SCW signaling pathway#P06212>DPP#P06272;DPP signaling pathway#P06213>DPP full length#P06282 IXOSC|EnsemblGenome=LOC8027468|UniProtKB=A0ACM8G5N4 A0ACM8G5N4 LOC8027468 PTHR45620:SF42 PDF RECEPTOR-LIKE PROTEIN-RELATED G PROTEIN-COUPLED RECEPTOR SEB-2 molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121838037|UniProtKB=A0ACM8G5Z1 A0ACM8G5Z1 LOC121838037 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115311842|UniProtKB=A0ACM8FYT3 A0ACM8FYT3 LOC115311842 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8024932|UniProtKB=A0ACM8DNN6 A0ACM8DNN6 LOC8024932 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8035636|UniProtKB=A0ACM8EJ67 A0ACM8EJ67 LOC8035636 PTHR11923:SF51 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 FI02050P-RELATED cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC120839578|UniProtKB=A0ACM8ELJ4 A0ACM8ELJ4 LOC120839578 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120841566|UniProtKB=A0ACM8FF65 A0ACM8FF65 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8025149|UniProtKB=A0ACM8DVM7 A0ACM8DVM7 LOC8025149 PTHR14024:SF49 PERILIPIN LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 1 regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;lipid storage#GO:0019915;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8028897|UniProtKB=A0ACM8E8B9 A0ACM8E8B9 BicD PTHR31233:SF6 BICAUDAL D FAMILY MEMBER PROTEIN BICAUDAL D protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092 regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cellular component organization#GO:0016043;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;microtubule anchoring#GO:0034453;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;microtubule-based process#GO:0007017;intracellular protein localization#GO:0008104;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8053378|UniProtKB=A0ACM8DTX0 A0ACM8DTX0 Doa PTHR45646:SF11 SERINE/THREONINE-PROTEIN KINASE DOA-RELATED SERINE_THREONINE-PROTEIN KINASE DOA transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120842690|UniProtKB=A0ACM8EUD2 A0ACM8EUD2 LOC120842690 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8029713|UniProtKB=A0ACM8FNK6 A0ACM8FNK6 PTHR24270:SF70 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 apolipoprotein#PC00052;transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115325794|UniProtKB=A0ACM8ER02 A0ACM8ER02 LOC115325794 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234 mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402 microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;transferase complex#GO:1990234;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8041659|UniProtKB=A0ACM8G0U1 A0ACM8G0U1 LOC8041659 PTHR11360:SF326 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 8-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC121837807|UniProtKB=A0ACM8G590 A0ACM8G590 LOC121837807 PTHR24381:SF470 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8031410|UniProtKB=A0ACM8E5L2 A0ACM8E5L2 LOC8031410 PTHR10807:SF73 MYOTUBULARIN-RELATED LD06050P binding#GO:0005488;phosphatase binding#GO:0019902;enzyme binding#GO:0019899;hydrolase activity#GO:0016787;protein binding#GO:0005515;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;protein phosphatase binding#GO:0019903 phosphatidylinositol dephosphorylation#GO:0046856;negative regulation of catabolic process#GO:0009895;dephosphorylation#GO:0016311;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;phospholipid metabolic process#GO:0006644;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;lipid modification#GO:0030258;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637;biological regulation#GO:0065007;glycerophospholipid metabolic process#GO:0006650 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8023510|UniProtKB=A0ACM8ECN4 A0ACM8ECN4 mRpS23 PTHR15925:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S23 SMALL RIBOSOMAL SUBUNIT PROTEIN MS23 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121833211|UniProtKB=A0ACM8FKU2 A0ACM8FKU2 LOC121833211 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115311774|UniProtKB=A0ACM8EQX5 A0ACM8EQX5 LOC115311774 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042265|UniProtKB=A0ACM8DSC5 A0ACM8DSC5 alpha-Man-Ib PTHR11742:SF55 MANNOSYL-OLIGOSACCHARIDE ALPHA-1,2-MANNOSIDASE-RELATED ENDOPLASMIC RETICULUM MANNOSYL-OLIGOSACCHARIDE 1,2-ALPHA-MANNOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115321884|UniProtKB=A0ACM8ELI9 A0ACM8ELI9 LOC115321884 PTHR45620:SF44 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTOR, ORPHAN-RELATED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121048327|UniProtKB=A0ACM8FVL8 A0ACM8FVL8 LOC121048327 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8050435|UniProtKB=A0ACM8DYT6 A0ACM8DYT6 Nop60B PTHR23127:SF0 CENTROMERE/MICROTUBULE BINDING PROTEIN CBF5 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT DKC1 isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA modification#GO:0016556;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077;centromere DNA-binding protein#PC00071 IXOSC|EnsemblGenome=LOC115324260|UniProtKB=A0ACM8E514 A0ACM8E514 LOC115324260 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115320817|UniProtKB=A0ACM8E1C8 A0ACM8E1C8 LOC115320817 PTHR11893:SF41 INNEXIN INNEXIN INX2 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 response to external stimulus#GO:0009605;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to radiation#GO:0009314;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 gap junction#PC00105 IXOSC|EnsemblGenome=LOC121837879|UniProtKB=A0ACM8G6V1 A0ACM8G6V1 LOC121837879 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836200|UniProtKB=A0ACM8FXY1 A0ACM8FXY1 LOC121836200 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8037546|UniProtKB=A0ACM8DK18 A0ACM8DK18 LOC8037546 PTHR46242:SF1 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 ZCCHC9 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 9 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8040950|UniProtKB=A0ACM8EDH1 A0ACM8EDH1 LOC8040950 PTHR31247:SF5 TRANSMEMBRANE PROTEIN 198 FAMILY MEMBER TRANSMEMBRANE PROTEIN 198 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8029891|UniProtKB=A0ACM8E9W8 A0ACM8E9W8 msl-3 PTHR10880:SF55 MORTALITY FACTOR 4-LIKE PROTEIN MSL COMPLEX SUBUNIT 3 chromatin-protein adaptor activity#GO:0140463;chromatin binding#GO:0003682;histone reader activity#GO:0140566;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115325058|UniProtKB=A0ACM8E5B7 A0ACM8E5B7 LOC115325058 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312706|UniProtKB=A0ACM8G6W9 A0ACM8G6W9 LOC121838231 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC120841470|UniProtKB=A0ACM8ESP4 A0ACM8ESP4 LSm3 PTHR13110:SF0 U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM3 LSM3 HOMOLOG, U6 SMALL NUCLEAR RNA AND MRNA DEGRADATION ASSOCIATED binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;P-body#GO:0000932;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;U4/U6 x U5 tri-snRNP complex#GO:0046540;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115319610|UniProtKB=A0ACM8G3N6 A0ACM8G3N6 LOC115319610 PTHR47526:SF6 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8032367|UniProtKB=A0ACM8DJE1 A0ACM8DJE1 LOC8032367 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;protein folding#GO:0006457;protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to heat#GO:0009408;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC120844815|UniProtKB=A0ACM8EZA4 A0ACM8EZA4 LOC120844815 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322390|UniProtKB=A0ACM8E1Z2 A0ACM8E1Z2 RpL29 PTHR12884:SF0 60S RIBOSOMAL PROTEIN L29 60S RIBOSOMAL PROTEIN L29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8033636|UniProtKB=A0ACM8EBS1 A0ACM8EBS1 LOC8033636 PTHR14085:SF3 WD-REPEAT PROTEIN BING4 WD REPEAT-CONTAINING PROTEIN 46 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;small-subunit processome#GO:0032040;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC8039713|UniProtKB=A0ACM8DZ13 A0ACM8DZ13 LOC8039713 PTHR24110:SF3 CENTROSOMAL PROTEIN OF 78 KDA CENTROSOMAL PROTEIN OF 78 KDA cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;cilium organization#GO:0044782;plasma membrane bounded cell projection organization#GO:0120036 ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;intracellular organelle#GO:0043229;cilium#GO:0005929;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995 IXOSC|EnsemblGenome=LOC115326601|UniProtKB=A0ACM8EQ02 A0ACM8EQ02 LOC115326601 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115325148|UniProtKB=A0ACM8E5D5 A0ACM8E5D5 LOC115325148 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322516|UniProtKB=A0ACM8E251 A0ACM8E251 LOC115322516 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037598|UniProtKB=A0ACM8FSV4 A0ACM8FSV4 LOC8037598 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8035036|UniProtKB=A0ACM8DPS4 A0ACM8DPS4 LOC8035036 PTHR24056:SF189 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;cyclin binding#GO:0030332;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;transferase complex#GO:1990234;protein kinase complex#GO:1902911;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120848299|UniProtKB=A0ACM8F5I7 A0ACM8F5I7 LOC120848299 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8037500|UniProtKB=A0ACM8DI45 A0ACM8DI45 LOC8037500 PTHR28672:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 ANAPHASE-PROMOTING COMPLEX SUBUNIT 13 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein K11-linked ubiquitination#GO:0070979;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 nucleus#GO:0005634;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 IXOSC|EnsemblGenome=LOC120844911|UniProtKB=A0ACM8F021 A0ACM8F021 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8036968|UniProtKB=A0ACM8G5Z0 A0ACM8G5Z0 LOC8036968 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8051397|UniProtKB=A0ACM8FES4 A0ACM8FES4 LOC8051397 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D cellular process#GO:0009987;nervous system development#GO:0007399;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115309285|UniProtKB=A0ACM8F0D7 A0ACM8F0D7 LOC115309285 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8031709|UniProtKB=A0ACM8E7R4 A0ACM8E7R4 LOC8031709 PTHR23276:SF2 PROTEIN PRRC1 PROTEIN PRRC1 binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515 multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;multicellular organismal-level homeostasis#GO:0048871;homeostatic process#GO:0042592;tissue homeostasis#GO:0001894;epithelial structure maintenance#GO:0010669 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121836115|UniProtKB=A0ACM8FXE8 A0ACM8FXE8 LOC121836115 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC120850151|UniProtKB=A0ACM8G7P6 A0ACM8G7P6 LOC120850151 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031157|UniProtKB=A0ACM8E3H5 A0ACM8E3H5 LOC8031157 PTHR21528:SF0 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC115321482|UniProtKB=A0ACM8E157 A0ACM8E157 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312187|UniProtKB=A0ACM8FZF1 A0ACM8FZF1 LOC115312187 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8042689|UniProtKB=A0ACM8EQ12 A0ACM8EQ12 LOC8042689 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8042451|UniProtKB=A0ACM8DKX6 A0ACM8DKX6 LOC8042451 PTHR12283:SF5 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;zinc ion binding#GO:0008270;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;acyltransferase activity#GO:0016746;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 transferase#PC00220 IXOSC|EnsemblGenome=LOC121833231|UniProtKB=A0ACM8FKX2 A0ACM8FKX2 LOC121833231 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120843287|UniProtKB=A0ACM8EVS7 A0ACM8EVS7 LOC120843287 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031978|UniProtKB=A0ACM8E4N5 A0ACM8E4N5 LOC8031978 PTHR36299:SF2 AGAP008005-PA DUF4773 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047403|UniProtKB=A0ACM8FFX6 A0ACM8FFX6 LOC121047403 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8027605|UniProtKB=A0ACM8DTP9 A0ACM8DTP9 c12.1 PTHR12718:SF2 CELL CYCLE CONTROL PROTEIN CWF15 SPLICEOSOME-ASSOCIATED PROTEIN CWC15 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC120837243|UniProtKB=A0ACM8FY58 A0ACM8FY58 LOC120837243 PTHR11426:SF263 HISTONE H3 HISTONE H3.X-RELATED cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;localization#GO:0051179;kinetochore organization#GO:0051383;organelle fission#GO:0048285;organelle assembly#GO:0070925;nuclear division#GO:0000280;organelle localization#GO:0051640;kinetochore assembly#GO:0051382;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120838964|UniProtKB=A0ACM8EKD1 A0ACM8EKD1 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120846698|UniProtKB=A0ACM8F2R3 A0ACM8F2R3 LOC120846698 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8040841|UniProtKB=A0ACM8EPL1 A0ACM8EPL1 LOC8040841 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8037275|UniProtKB=A0ACM8E049 A0ACM8E049 LOC8037275 PTHR45831:SF2 LD24721P LD24721P establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115328797|UniProtKB=A0ACM8EA35 A0ACM8EA35 LOC115328797 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120845270|UniProtKB=A0ACM8F0G8 A0ACM8F0G8 LOC120845270 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836175|UniProtKB=A0ACM8EPI7 A0ACM8EPI7 LOC120836175 PTHR10024:SF227 SYNAPTOTAGMIN SYNAPTOTAGMIN 1 protein binding#GO:0005515;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488 modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of exocytosis#GO:0017157;cell communication#GO:0007154;regulation of secretion#GO:0051046;localization#GO:0051179;secretion#GO:0046903;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;export from cell#GO:0140352;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;regulation of cellular component organization#GO:0051128;regulation of neurotransmitter secretion#GO:0046928;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;positive regulation of cellular component organization#GO:0051130;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;neurotransmitter transport#GO:0006836;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;positive regulation of transport#GO:0051050;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;synaptic signaling#GO:0099536;exocytosis#GO:0006887;positive regulation of vesicle fusion#GO:0031340;regulation of transport#GO:0051049;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055 axon#GO:0030424;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 IXOSC|EnsemblGenome=LOC8034846|UniProtKB=A0ACM8F1R0 A0ACM8F1R0 LOC8034846 PTHR23079:SF55 RNA-DEPENDENT RNA POLYMERASE RNA-DIRECTED RNA POLYMERASE catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772 negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8052228|UniProtKB=A0ACM8EKD8 A0ACM8EKD8 LOC8052228 PTHR23220:SF122 INTEGRIN ALPHA INTEGRIN ALPHA-PS1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cell-substrate adhesion#GO:0031589;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229 cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941 IXOSC|EnsemblGenome=LOC121836479|UniProtKB=A0ACM8G044 A0ACM8G044 LOC121836479 PTHR11177:SF410 CHITINASE HISTIDINE-RICH CARBOXYL TERMINUS PROTEIN 1 ISOFORM X1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;chitin metabolic process#GO:0006030;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8031121|UniProtKB=A0ACM8EMH0 A0ACM8EMH0 dsd PTHR46376:SF2 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 DISTRACTED, ISOFORM B DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC115320859|UniProtKB=A0ACM8EMU4 A0ACM8EMU4 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120837672|UniProtKB=A0ACM8EIZ4 A0ACM8EIZ4 LOC120837672 PTHR43563:SF26 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;phenol-containing compound metabolic process#GO:0018958;amine metabolic process#GO:0009308;serotonin metabolic process#GO:0042428;amine catabolic process#GO:0009310;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxidase#PC00175 Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 IXOSC|EnsemblGenome=LOC8027259|UniProtKB=A0ACM8DVZ1 A0ACM8DVZ1 LOC8027259 PTHR12227:SF0 GLYCERATE KINASE GLYCERATE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 carbohydrate kinase#PC00065 IXOSC|EnsemblGenome=ISCI018603|UniProtKB=B7PKZ2 B7PKZ2 IscW_ISCW018603 PTHR46186:SF2 CYSTATIN CYSTATIN-RELATED peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 extracellular region#GO:0005576;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115327527|UniProtKB=A0ACM8FTU2 A0ACM8FTU2 LOC115327527 PTHR47327:SF1 FI18240P1-RELATED FI18240P1-RELATED anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856 IXOSC|EnsemblGenome=LOC120836058|UniProtKB=A0ACM8G478 A0ACM8G478 LOC120836058 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115331484|UniProtKB=A0ACM8FA30 A0ACM8FA30 LOC115331484 PTHR20843:SF0 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 10 PROTEIN AVEUGLE response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC115331859|UniProtKB=A0ACM8FMM8 A0ACM8FMM8 PTHR14119:SF19 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8037755|UniProtKB=A0ACM8EB28 A0ACM8EB28 sip1 PTHR23329:SF1 TUFTELIN-INTERACTING PROTEIN 11-RELATED TUFTELIN-INTERACTING PROTEIN 11 protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-containing complex disassembly#GO:0032984;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8028820|UniProtKB=A0ACM8DSQ2 A0ACM8DSQ2 nito PTHR23189:SF137 RNA RECOGNITION MOTIF-CONTAINING RNA-BINDING PROTEIN SPENITO binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120849079|UniProtKB=A0ACM8F639 A0ACM8F639 LOC120849079 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8052247|UniProtKB=A0ACM8EAP4 A0ACM8EAP4 pasilla PTHR10288:SF339 KH DOMAIN CONTAINING RNA BINDING PROTEIN RNA-BINDING PROTEIN PASILLA mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of RNA splicing#GO:0043484;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120847075|UniProtKB=A0ACM8F4Q3 A0ACM8F4Q3 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120838435|UniProtKB=A0ACM8EJS8 A0ACM8EJS8 LOC120838435 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8027431|UniProtKB=A0ACM8FU38 A0ACM8FU38 vermilion PTHR10138:SF0 TRYPTOPHAN 2,3-DIOXYGENASE TRYPTOPHAN 2,3-DIOXYGENASE binding#GO:0005488;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;tetrapyrrole binding#GO:0046906 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120841730|UniProtKB=A0ACM8G5U2 A0ACM8G5U2 LOC120841730 PTHR45620:SF44 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTOR, ORPHAN-RELATED molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115311845|UniProtKB=A0ACM8G2V2 A0ACM8G2V2 LOC115311845 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8038076|UniProtKB=A0ACM8EHK3 A0ACM8EHK3 LOC8038076 PTHR11730:SF60 AMMONIUM TRANSPORTER RH50, ISOFORM D transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;homeostatic process#GO:0042592;transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8027406|UniProtKB=A0ACM8E2F0 A0ACM8E2F0 ACOX1 PTHR10909:SF250 ELECTRON TRANSPORT OXIDOREDUCTASE ACYL-COENZYME A OXIDASE-RELATED lipid binding#GO:0008289;fatty acid binding#GO:0005504;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;organic acid binding#GO:0043177;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824 lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115331147|UniProtKB=A0ACM8F442 A0ACM8F442 LOC115331147 PTHR43503:SF4 MCG48959-RELATED PEROXIREDOXIN-6 antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 homeostatic process#GO:0042592;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 oxidoreductase#PC00176;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC8052983|UniProtKB=A0ACM8EI01 A0ACM8EI01 Lnpk PTHR22166:SF12 ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK ENDOPLASMIC RETICULUM JUNCTION FORMATION PROTEIN LUNAPARK cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum tubular network#GO:0071782 IXOSC|EnsemblGenome=LOC115332973|UniProtKB=A0ACM8EEV4 A0ACM8EEV4 LOC115332973 PTHR18976:SF34 APOLIPOPROTEIN LIPID-BINDING PROTEIN apolipoprotein#PC00052;transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120848537|UniProtKB=A0ACM8F525 A0ACM8F525 PTHR12864:SF89 RAN BINDING PROTEIN 9-RELATED SPRY DOMAIN-CONTAINING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115321447|UniProtKB=A0ACM8FTJ9 A0ACM8FTJ9 LOC121835358 PTHR28520:SF15 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 MITOTIC-SPINDLE ORGANIZING PROTEIN 1 mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;microtubule nucleation#GO:0007020;nuclear division#GO:0000280;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;supramolecular fiber organization#GO:0097435;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;organelle assembly#GO:0070925;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;microtubule polymerization or depolymerization#GO:0031109;chromosome organization#GO:0051276;microtubule polymerization#GO:0046785;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051 microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115310366|UniProtKB=A0ACM8DPU7 A0ACM8DPU7 LOC115310366 PTHR11530:SF11 D-AMINO ACID OXIDASE D-AMINO ACID OXIDASE 2, ISOFORM A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 IXOSC|EnsemblGenome=LOC115310978|UniProtKB=A0ACM8FS36 A0ACM8FS36 LOC115310978 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313296|UniProtKB=A0ACM8DT34 A0ACM8DT34 LOC115313296 PTHR46191:SF2 FAMILY NOT NAMED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 3 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8042195|UniProtKB=A0ACM8EDN0 A0ACM8EDN0 LOC8042195 PTHR12316:SF17 NINJURIN-RELATED NINJURIN-A cell-cell adhesion mediator activity#GO:0098632;protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 programmed cell death#GO:0012501;cell adhesion#GO:0007155;cell death#GO:0008219;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115314978|UniProtKB=A0ACM8G5C4 A0ACM8G5C4 LOC115314978 PTHR24376:SF235 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115332089|UniProtKB=A0ACM8EKP9 A0ACM8EKP9 LOC115332089 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045738|UniProtKB=A0ACM8FTI7 A0ACM8FTI7 LOC121838326 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053319|UniProtKB=A0ACM8DY44 A0ACM8DY44 LOC8053319 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN transferase#PC00220;acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC8028331|UniProtKB=A0ACM8DJP0 A0ACM8DJP0 LOC8028331 PTHR21373:SF1 GLUCOSE REPRESSIBLE PROTEIN MAK10 N-ALPHA-ACETYLTRANSFERASE 35, NATC AUXILIARY SUBUNIT regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066 protein acetyltransferase complex#GO:0031248;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC115330004|UniProtKB=A0ACM8EIW7 A0ACM8EIW7 LOC115330004 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325626|UniProtKB=A0ACM8FLF5 A0ACM8FLF5 LOC115325626 PTHR43767:SF1 LONG-CHAIN-FATTY-ACID--COA LIGASE NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121838146|UniProtKB=A0ACM8G894 A0ACM8G894 LOC121838146 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8037246|UniProtKB=A0ACM8FGW4 A0ACM8FGW4 LOC8037246 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8038709|UniProtKB=A0ACM8EYT3 A0ACM8EYT3 LOC8038709 PTHR11846:SF0 ADENYLOSUCCINATE SYNTHETASE ADENYLOSUCCINATE SYNTHETASE catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate biosynthetic process#GO:0090407;IMP metabolic process#GO:0046040;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;carbohydrate derivative metabolic process#GO:1901135 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;ligase#PC00142 Wnt signaling pathway#P00057>NFAT Target Genes#G01559;De novo purine biosynthesis#P02738>Adenylosuccinate synthase#P02890 IXOSC|EnsemblGenome=LOC120839182|UniProtKB=A0ACM8EMI9 A0ACM8EMI9 LOC120839182 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317271|UniProtKB=A0ACM8EL68 A0ACM8EL68 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8035418|UniProtKB=A0ACM8F0X2 A0ACM8F0X2 LOC8035418 PTHR11920:SF516 GUANYLYL CYCLASE GUANYLATE CYCLASE 32E catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;peptide receptor activity#GO:0001653;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;lyase activity#GO:0016829;molecular transducer activity#GO:0060089 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanylate cyclase#PC00114;lyase#PC00144 IXOSC|EnsemblGenome=LOC8028923|UniProtKB=A0ACM8FJW4 A0ACM8FJW4 LOC8028923 PTHR10684:SF4 NUCLEAR RECEPTOR COACTIVATOR TAIMAN, ISOFORM G DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;transcription regulator activity#GO:0140110;binding#GO:0005488;transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;nuclear receptor binding#GO:0016922;transcription factor binding#GO:0008134 regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to hormone#GO:0009725;positive regulation of transcription by RNA polymerase II#GO:0045944;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to chemical stimulus#GO:0070887 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8026867|UniProtKB=A0ACM8FBB7 A0ACM8FBB7 PTHR23120:SF0 MAESTRO-RELATED HEAT DOMAIN-CONTAINING MAESTRO HEAT-LIKE REPEAT-CONTAINING PROTEIN FAMILY MEMBER 1 ISOFORM X1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120846589|UniProtKB=A0ACM8F2Q1 A0ACM8F2Q1 LOC120846589 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120842550|UniProtKB=A0ACM8ETW2 A0ACM8ETW2 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC121833607|UniProtKB=A0ACM8FLV7 A0ACM8FLV7 LOC121833607 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309464|UniProtKB=A0ACM8ERN0 A0ACM8ERN0 LOC115309464 PTHR22930:SF269 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041670|UniProtKB=A0ACM8F106 A0ACM8F106 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8030720|UniProtKB=A0ACM8DQS4 A0ACM8DQS4 Prosalpha4 PTHR11599:SF237 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-7-1-RELATED macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;proteasome complex#GO:0000502;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 IXOSC|EnsemblGenome=LOC115312170|UniProtKB=A0ACM8G613 A0ACM8G613 LOC115312170 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120840794|UniProtKB=A0ACM8EQF3 A0ACM8EQF3 LOC120840794 PTHR45938:SF14 ACP24A4-RELATED IXOLARIS IXOSC|EnsemblGenome=LOC8030791|UniProtKB=A0ACM8DHI1 A0ACM8DHI1 LOC8030791 PTHR13475:SF6 NEUGRIN FI11059P cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrial ribosome assembly#GO:0061668;ribosome assembly#GO:0042255;organelle assembly#GO:0070925;ribosome biogenesis#GO:0042254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115314532|UniProtKB=A0ACM8F3J8 A0ACM8F3J8 LOC115314532 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034125|UniProtKB=A0ACM8ED41 A0ACM8ED41 LOC8034125 PTHR12308:SF51 ANOCTAMIN ANOCTAMIN-8 intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC120848866|UniProtKB=A0ACM8FMJ7 A0ACM8FMJ7 LOC120848866 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115308768|UniProtKB=A0ACM8FQ44 A0ACM8FQ44 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313351|UniProtKB=A0ACM8EK04 A0ACM8EK04 LOC115313351 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8051895|UniProtKB=A0ACM8FRF7 A0ACM8FRF7 LOC8051895 PTHR10218:SF367 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN G(F) SUBUNIT ALPHA molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;multicellular organismal process#GO:0032501;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;G protein-coupled dopamine receptor signaling pathway#GO:0007212;system process#GO:0003008;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;sensory perception of chemical stimulus#GO:0007606;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to nitrogen compound#GO:1901698;cell communication#GO:0007154;nervous system process#GO:0050877;sensory perception#GO:0007600;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186 catalytic complex#GO:1902494;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cytoplasmic side of plasma membrane#GO:0009898;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;cytoplasmic side of membrane#GO:0098562;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737 heterotrimeric G-protein#PC00117;G-protein#PC00020 Enkephalin release#P05913>G-Protein (s)#P05977;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430 IXOSC|EnsemblGenome=LOC8031382|UniProtKB=A0ACM8EF96 A0ACM8EF96 LOC8031382 PTHR12072:SF5 CWF19, CELL CYCLE CONTROL PROTEIN CWF19-LIKE PROTEIN 2 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120836173|UniProtKB=A0ACM8G8W6 A0ACM8G8W6 LOC120836173 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8050950|UniProtKB=A0ACM8FE86 A0ACM8FE86 LOC8050950 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8051330|UniProtKB=A0ACM8E1M0 A0ACM8E1M0 LOC8051330 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039541|UniProtKB=A0ACM8DPR2 A0ACM8DPR2 RpS27 PTHR11594:SF0 40S RIBOSOMAL PROTEIN S27 40S RIBOSOMAL PROTEIN S27 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;translation#GO:0006412;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120837690|UniProtKB=A0ACM8EI57 A0ACM8EI57 LOC120837690 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115319911|UniProtKB=A0ACM8E091 A0ACM8E091 Stt3A PTHR13872:SF43 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3A glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;protein modification process#GO:0036211;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687 transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8039699|UniProtKB=A0ACM8DKE8 A0ACM8DKE8 LOC8039699 PTHR45695:SF38 LEUCOKININ RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 83 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120837250|UniProtKB=A0ACM8F4J0 A0ACM8F4J0 LOC121836244 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050905|UniProtKB=A0ACM8DQ36 A0ACM8DQ36 PTHR46292:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 102A COILED-COIL DOMAIN-CONTAINING PROTEIN 102A IXOSC|EnsemblGenome=LOC121834862|UniProtKB=A0ACM8FSL6 A0ACM8FSL6 LOC121834862 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121835084|UniProtKB=A0ACM8FSC5 A0ACM8FSC5 LOC121835084 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8035999|UniProtKB=A0ACM8DH37 A0ACM8DH37 LOC8035999 PTHR14110:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM22 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;membrane organization#GO:0061024;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrial protein import pathway#GO:7770058;mitochondrion organization#GO:0007005;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;mitochondrial transport#GO:0006839 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 transporter#PC00227 IXOSC|EnsemblGenome=LOC8023818|UniProtKB=A0ACM8DYW5 A0ACM8DYW5 LOC8023818 PTHR22807:SF34 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(72)-C(5))-METHYLTRANSFERASE NSUN6 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a rRNA#GO:0140102;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;tRNA methyltransferase activity#GO:0008175 ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;tRNA modification#GO:0006400;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;rRNA methylation#GO:0031167;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;rRNA base methylation#GO:0070475;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC121047094|UniProtKB=A0ACM8G6B1 A0ACM8G6B1 LOC121047094 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042128|UniProtKB=A0ACM8DKV3 A0ACM8DKV3 LOC8042128 PTHR11119:SF3 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER LD30822P transporter#PC00227 IXOSC|EnsemblGenome=LOC8027216|UniProtKB=A0ACM8DIV0 A0ACM8DIV0 LOC8027216 PTHR12842:SF6 FI01459P FI01459P IXOSC|EnsemblGenome=LOC115329951|UniProtKB=A0ACM8FNC6 A0ACM8FNC6 PTHR43690:SF37 NARDILYSIN INSULIN-DEGRADING ENZYME catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteolysis#GO:0006508;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171 mitochondrion#GO:0005739;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115328048|UniProtKB=A0ACM8EF73 A0ACM8EF73 LOC115328048 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8030196|UniProtKB=A0ACM8FWV9 A0ACM8FWV9 LOC8030196 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121837721|UniProtKB=A0ACM8G4W7 A0ACM8G4W7 LOC121837721 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8035993|UniProtKB=A0ACM8FGW3 A0ACM8FGW3 PTHR21818:SF0 BC025462 PROTEIN FANCONI ANEMIA GROUP I PROTEIN cellular response to stress#GO:0033554;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of protein modification by small protein conjugation or removal#GO:1903320;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;DNA repair complex#GO:1990391 IXOSC|EnsemblGenome=LOC121047363|UniProtKB=A0ACM8FGZ1 A0ACM8FGZ1 LOC121047363 PTHR45632:SF36 LD33804P RING ZINC FINGER-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8038087|UniProtKB=A0ACM8DWU5 A0ACM8DWU5 LOC8038087 PTHR45946:SF4 HOMEOBOX PROTEIN ROUGH-RELATED HOMEOBOX PROTEIN ROUGH-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC120844209|UniProtKB=A0ACM8EY38 A0ACM8EY38 LOC120844209 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8028381|UniProtKB=A0ACM8FS62 A0ACM8FS62 LOC8028381 PTHR11972:SF58 NADPH OXIDASE NADPH OXIDASE 5 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 cellular process#GO:0009987;metabolic process#GO:0008152;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593;defense response#GO:0006952;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801 catalytic complex#GO:1902494;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204 oxidase#PC00175;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8042625|UniProtKB=A0ACM8EF43 A0ACM8EF43 LOC8042625 PTHR24034:SF111 EGF-LIKE DOMAIN-CONTAINING PROTEIN RE64043P extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102;extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8029097|UniProtKB=A0ACM8EEB3 A0ACM8EEB3 mRpL24 PTHR12903:SF0 MITOCHONDRIAL RIBOSOMAL PROTEIN L24 LARGE RIBOSOMAL SUBUNIT PROTEIN UL24M biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8050914|UniProtKB=A0ACM8DLT0 A0ACM8DLT0 LOC8050914 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8038861|UniProtKB=A0ACM8FHW5 A0ACM8FHW5 LOC8038861 PTHR43782:SF5 ARGINASE ARGINASE cation binding#GO:0043169;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115315509|UniProtKB=A0ACM8ESP5 A0ACM8ESP5 LOC115315509 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025846|UniProtKB=A0ACM8FZC6 A0ACM8FZC6 LOC8025846 PTHR45702:SF2 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 IXOSC|EnsemblGenome=LOC121838153|UniProtKB=A0ACM8G7Z5 A0ACM8G7Z5 LOC121838153 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC121835631|UniProtKB=A0ACM8FWB1 A0ACM8FWB1 LOC121835631 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8037877|UniProtKB=A0ACM8DQA9 A0ACM8DQA9 LOC8037877 PTHR23086:SF101 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE 59B, ISOFORM J-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transferase#PC00220;kinase#PC00137 IXOSC|EnsemblGenome=LOC8037437|UniProtKB=A0ACM8E5X0 A0ACM8E5X0 LOC8037437 PTHR13217:SF6 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7 guanyl-nucleotide exchange factor activity#GO:0005085;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 IXOSC|EnsemblGenome=LOC121046722|UniProtKB=A0ACM8FEN8 A0ACM8FEN8 LOC121046722 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8031735|UniProtKB=A0ACM8F4Z3 A0ACM8F4Z3 PTHR19444:SF56 UNC-93 RELATED UNC93-LIKE PROTEIN transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of system process#GO:0044057;regulation of muscle contraction#GO:0006937;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;homeostatic process#GO:0042592;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;cell periphery#GO:0071944;contractile muscle fiber#GO:0043292;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 IXOSC|EnsemblGenome=LOC8031932|UniProtKB=A0ACM8DIZ1 A0ACM8DIZ1 PTHR21377:SF0 PROTEIN FAM210B, MITOCHONDRIAL PROTEIN FAM210B, MITOCHONDRIAL intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967 IXOSC|EnsemblGenome=LOC8037705|UniProtKB=A0ACM8E971 A0ACM8E971 LOC8037705 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120843670|UniProtKB=A0ACM8EWN4 A0ACM8EWN4 LOC120843670 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833891|UniProtKB=A0ACM8FNI5 A0ACM8FNI5 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8051779|UniProtKB=A0ACM8EU97 A0ACM8EU97 LOC8051779 PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;lysosome#GO:0005764;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 glycosidase#PC00110;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115312036|UniProtKB=A0ACM8DRH5 A0ACM8DRH5 Plap PTHR19849:SF0 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN PHOSPHOLIPASE A2 ACTIVATOR PROTEIN, ISOFORM A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasomal protein catabolic process#GO:0010498;macroautophagy#GO:0016236;cellular process#GO:0009987;autophagy#GO:0006914;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8024648|UniProtKB=A0ACM8F5P5 A0ACM8F5P5 LOC8024648 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120848526|UniProtKB=A0ACM8G7A4 A0ACM8G7A4 LOC120848526 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121835175|UniProtKB=A0ACM8FRU8 A0ACM8FRU8 LOC121835175 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 IXOSC|EnsemblGenome=LOC115325869|UniProtKB=A0ACM8E5Y3 A0ACM8E5Y3 LOC115325869 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8043435|UniProtKB=A0ACM8F8U5 A0ACM8F8U5 LOC8043435 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED carboxylic acid transmembrane transporter activity#GO:0046943;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC120844169|UniProtKB=A0ACM8FGL1 A0ACM8FGL1 LOC120844169 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;alpha-glucosidase activity#GO:0090599;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC120843304|UniProtKB=A0ACM8EVS8 A0ACM8EVS8 LOC120843304 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 transferase#PC00220 IXOSC|EnsemblGenome=LOC8040620|UniProtKB=A0ACM8DH01 A0ACM8DH01 PTHR15664:SF21 C20ORF30 PROTEIN TRANSMEMBRANE PROTEIN 230 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC115314236|UniProtKB=A0ACM8DTL3 A0ACM8DTL3 LOC115314236 PTHR21304:SF0 MICOS COMPLEX SUBUNIT MIC10 MICOS COMPLEX SUBUNIT MIC10 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC8041809|UniProtKB=A0ACM8DKQ1 A0ACM8DKQ1 LOC8041809 PTHR12311:SF7 ACTIVATOR OF BASAL TRANSCRIPTION 1 ACTIVATOR OF BASAL TRANSCRIPTION 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8029212|UniProtKB=A0ACM8DPJ5 A0ACM8DPJ5 LOC8029212 PTHR24031:SF91 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX24 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115314118|UniProtKB=A0ACM8DTU8 A0ACM8DTU8 LOC115314118 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115327809|UniProtKB=A0ACM8EV57 A0ACM8EV57 LOC115327809 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120840671|UniProtKB=A0ACM8EP62 A0ACM8EP62 LOC120840671 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035450|UniProtKB=A0ACM8G3H5 A0ACM8G3H5 LOC8035450 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8042873|UniProtKB=A0ACM8FVS8 A0ACM8FVS8 LOC8042873 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8041395|UniProtKB=A0ACM8F746 A0ACM8F746 LOC8041395 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC120840897|UniProtKB=A0ACM8EQJ3 A0ACM8EQJ3 Bet5 PTHR23249:SF16 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 1 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular vesicle#GO:0097708;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115332299|UniProtKB=A0ACM8G8L5 A0ACM8G8L5 LOC115332299 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8026494|UniProtKB=A0ACM8DHU6 A0ACM8DHU6 LOC8026494 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120843367|UniProtKB=A0ACM8EX17 A0ACM8EX17 LOC120843367 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8039607|UniProtKB=A0ACM8E1W3 A0ACM8E1W3 LOC8039607 PTHR28032:SF1 FI02826P FI02826P binding#GO:0005488;protein-containing complex binding#GO:0044877 localization#GO:0051179;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;cellular response to topologically incorrect protein#GO:0035967;modification-dependent macromolecule catabolic process#GO:0043632;response to topologically incorrect protein#GO:0035966;catabolic process#GO:0009056;response to stimulus#GO:0050896;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;response to misfolded protein#GO:0051788;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular response to misfolded protein#GO:0071218;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;macromolecule localization#GO:0033036;response to stress#GO:0006950 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane#GO:0016020;organelle envelope#GO:0031967;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115314971|UniProtKB=A0ACM8EFM6 A0ACM8EFM6 LOC115314971 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040722|UniProtKB=A0ACM8FFS8 A0ACM8FFS8 LOC8040722 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115316573|UniProtKB=A0ACM8DW10 A0ACM8DW10 LOC115316573 PTHR16110:SF1 TBC1 DOMAIN FAMILY MEMBER 19 TBC1 DOMAIN FAMILY MEMBER 19 IXOSC|EnsemblGenome=LOC120837943|UniProtKB=A0ACM8EI53 A0ACM8EI53 Uvrag PTHR15157:SF5 UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN UV RADIATION RESISTANCE-ASSOCIATED GENE PROTEIN lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;autophagy#GO:0006914;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;phospholipid biosynthetic process#GO:0008654;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;process utilizing autophagic mechanism#GO:0061919;phosphatidylinositol phosphate biosynthetic process#GO:0046854 lytic vacuole#GO:0000323;extrinsic component of membrane#GO:0019898;transferase complex#GO:1990234;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;phosphatidylinositol 3-kinase complex, class III#GO:0035032;endosome#GO:0005768;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796 IXOSC|EnsemblGenome=LOC8032610|UniProtKB=A0ACM8DQV6 A0ACM8DQV6 LOC8032610 PTHR23033:SF53 BETA1,3-GALACTOSYLTRANSFERASE N-ACETYLGALACTOSAMINIDE BETA-1,3-GALACTOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 transferase#PC00220 IXOSC|EnsemblGenome=LOC121833622|UniProtKB=A0ACM8FM35 A0ACM8FM35 LOC121833622 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120838002|UniProtKB=A0ACM8EIZ3 A0ACM8EIZ3 LOC120838002 PTHR11685:SF427 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING RBR-TYPE E3 UBIQUITIN TRANSFERASE enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120835950|UniProtKB=A0ACM8F4L8 A0ACM8F4L8 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121048118|UniProtKB=A0ACM8FQW3 A0ACM8FQW3 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120851141|UniProtKB=A0ACM8FKX7 A0ACM8FKX7 LOC120851141 PTHR10075:SF130 BASIGIN RELATED NEURAL CELL ADHESION MOLECULE L1 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8027067|UniProtKB=A0ACM8FK31 A0ACM8FK31 LOC8027067 PTHR22961:SF13 SER/THR PROTEIN KINASE-TRB TRIBBLES kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 positive regulation of metabolic process#GO:0009893;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of protein metabolic process#GO:0051247;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;biological regulation#GO:0065007;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115328862|UniProtKB=A0ACM8E8P8 A0ACM8E8P8 LOC121837313 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8040331|UniProtKB=A0ACM8DUZ0 A0ACM8DUZ0 LOC8040331 PTHR21630:SF10 VEPH-A/MELTED VENTRICULAR ZONE-EXPRESSED PH DOMAIN-CONTAINING PROTEIN HOMOLOG 1 phospholipid binding#GO:0005543;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8023191|UniProtKB=A0ACM8DQL5 A0ACM8DQL5 LOC8023191 PTHR16116:SF5 ZINC FINGER PROTEIN 839 ZINC FINGER PROTEIN 839 IXOSC|EnsemblGenome=LOC115333104|UniProtKB=A0ACM8F1X3 A0ACM8F1X3 LOC115333104 PTHR11358:SF26 ARGINASE/AGMATINASE GUANIDINO ACID HYDROLASE, MITOCHONDRIAL hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 polyamine biosynthetic process#GO:0006596;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120839737|UniProtKB=A0ACM8EMQ3 A0ACM8EMQ3 LOC120839737 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC120837046|UniProtKB=A0ACM8EGE2 A0ACM8EGE2 LOC120837046 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC115317533|UniProtKB=A0ACM8DXM8 A0ACM8DXM8 LOC115317533 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 IXOSC|EnsemblGenome=LOC8043999|UniProtKB=A0ACM8DS52 A0ACM8DS52 LOC8043999 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein refolding#GO:0042026;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC120841398|UniProtKB=A0ACM8ER63 A0ACM8ER63 LOC120841398 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8028751|UniProtKB=A0ACM8DN49 A0ACM8DN49 UbcE2H PTHR24068:SF128 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 H ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 IXOSC|EnsemblGenome=LOC8041111|UniProtKB=A0ACM8DTN5 A0ACM8DTN5 LOC8041111 PTHR44269:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED IP05441P alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8030473|UniProtKB=A0ACM8E7F6 A0ACM8E7F6 Uba2 PTHR10953:SF5 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 2 ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a protein#GO:0140096;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792 post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 IXOSC|EnsemblGenome=LOC120844097|UniProtKB=A0ACM8EXV2 A0ACM8EXV2 LOC120844097 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8039960|UniProtKB=A0ACM8DWJ7 A0ACM8DWJ7 PTHR21435:SF1 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM29 transport#GO:0006810;intracellular transport#GO:0046907;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrial protein import pathway#GO:7770058;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;mitochondrial transport#GO:0006839 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;TIM22 mitochondrial import inner membrane insertion complex#GO:0042721;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115329647|UniProtKB=A0ACM8EAU8 A0ACM8EAU8 LOC115329647 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310904|UniProtKB=A0ACM8F9B4 A0ACM8F9B4 LOC115310904 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115309334|UniProtKB=A0ACM8F755 A0ACM8F755 LOC115309334 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8029777|UniProtKB=A0ACM8DIT2 A0ACM8DIT2 LOC8029777 PTHR22776:SF97 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RE01453P signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115328061|UniProtKB=A0ACM8E7M8 A0ACM8E7M8 LOC115328061 PTHR45794:SF1 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8038489|UniProtKB=A0ACM8EC80 A0ACM8EC80 LOC8038489 PTHR24416:SF639 TYROSINE-PROTEIN KINASE RECEPTOR PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;cellular response to nerve growth factor stimulus#GO:1990090;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;signaling receptor complex#GO:0043235;axon#GO:0030424 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120840582|UniProtKB=A0ACM8EPS8 A0ACM8EPS8 LOC120840582 PTHR10751:SF29 GUANYLATE BINDING PROTEIN ATLASTIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462 cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840 G-protein#PC00020;heterotrimeric G-protein#PC00117 IXOSC|EnsemblGenome=LOC115325758|UniProtKB=A0ACM8E5V1 A0ACM8E5V1 LOC115325758 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031455|UniProtKB=A0ACM8DI92 A0ACM8DI92 PTHR12276:SF126 EPSIN/ENT-RELATED CLATHRIN INTERACTOR 1 lipid binding#GO:0008289;protein binding#GO:0005515;phospholipid binding#GO:0005543;binding#GO:0005488;clathrin binding#GO:0030276 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;vesicle coat#GO:0030120;cytoplasm#GO:0005737;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;clathrin-coated vesicle membrane#GO:0030665;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8034207|UniProtKB=A0ACM8FEY8 A0ACM8FEY8 LOC8034207 PTHR46260:SF3 RING-TYPE DOMAIN-CONTAINING PROTEIN KELCH REPEAT-CONTAINING PROTEIN DDB_G0274267-RELATED IXOSC|EnsemblGenome=LOC8034366|UniProtKB=A0ACM8DPG0 A0ACM8DPG0 312 PTHR21043:SF0 IOJAP SUPERFAMILY ORTHOLOG MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1 ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 membraneless organelle assembly#GO:0140694;mitochondrial large ribosomal subunit assembly#GO:1902775;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;organelle assembly#GO:0070925;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;ribosomal large subunit assembly#GO:0000027;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC120850540|UniProtKB=A0ACM8FA78 A0ACM8FA78 LOC120850540 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033766|UniProtKB=A0ACM8DIB0 A0ACM8DIB0 LOC8033766 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115327539|UniProtKB=A0ACM8EJK9 A0ACM8EJK9 LOC115327539 PTHR12274:SF3 GRANULIN GRANULIN PRECURSOR cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC115322401|UniProtKB=A0ACM8E211 A0ACM8E211 LOC115322401 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836578|UniProtKB=A0ACM8FYR3 A0ACM8FYR3 LOC121836578 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050997|UniProtKB=A0ACM8G8Q5 A0ACM8G8Q5 LOC8050997 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8052183|UniProtKB=A0ACM8DSI1 A0ACM8DSI1 Hs3st-B PTHR10605:SF72 HEPARAN SULFATE SULFOTRANSFERASE HEPARAN SULFATE 3-O SULFOTRANSFERASE-B, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8052639|UniProtKB=A0ACM8DNF8 A0ACM8DNF8 bel PTHR47958:SF216 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;reproductive process#GO:0022414;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;gamete generation#GO:0007276;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;multicellular organismal reproductive process#GO:0048609;sexual reproduction#GO:0019953 P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;nucleus#GO:0005634 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8035187|UniProtKB=A0ACM8EJC3 A0ACM8EJC3 mtSSB PTHR10302:SF0 SINGLE-STRANDED DNA-BINDING PROTEIN SINGLE-STRANDED DNA-BINDING PROTEIN, MITOCHONDRIAL single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;DNA binding#GO:0003677;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of DNA replication#GO:0045740;regulation of DNA replication#GO:0006275;positive regulation of metabolic process#GO:0009893;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of DNA metabolic process#GO:0051054;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of DNA-templated DNA replication#GO:0090329;regulation of organelle organization#GO:0033043;DNA replication#GO:0006260;regulation of DNA metabolic process#GO:0051052 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;mitochondrial nucleoid#GO:0042645;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoid#GO:0009295;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8051186|UniProtKB=A0ACM8E975 A0ACM8E975 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763 cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 IXOSC|EnsemblGenome=LOC8027133|UniProtKB=A0ACM8DQ13 A0ACM8DQ13 LOC8027133 PTHR13923:SF11 SEC31-RELATED PROTEIN PROTEIN TRANSPORT PROTEIN SEC31A vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;COPII-coated vesicle budding#GO:0090114;cellular component organization#GO:0016043 ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC115309449|UniProtKB=A0ACM8DNQ2 A0ACM8DNQ2 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846328|UniProtKB=A0ACM8F2Z9 A0ACM8F2Z9 LOC120846328 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121833828|UniProtKB=A0ACM8FMY7 A0ACM8FMY7 LOC121833828 PTHR24305:SF166 CYTOCHROME P450 CYTOCHROME P450 302A1, MITOCHONDRIAL-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120850465|UniProtKB=A0ACM8FVM5 A0ACM8FVM5 LOC120850465 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115315856|UniProtKB=A0ACM8FAB5 A0ACM8FAB5 LOC115315856 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120849696|UniProtKB=A0ACM8F778 A0ACM8F778 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120837611|UniProtKB=A0ACM8G959 A0ACM8G959 LOC120837611 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8035449|UniProtKB=A0ACM8G8X8 A0ACM8G8X8 LOC8035449 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115320026|UniProtKB=A0ACM8FDS5 A0ACM8FDS5 PTHR10707:SF10 CYTOCHROME C OXIDASE SUBUNIT IV CYTOCHROME C OXIDASE SUBUNIT 4 mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;electron transport chain#GO:0022900;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333 organelle membrane#GO:0031090;transporter complex#GO:1990351;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;respiratory chain complex IV#GO:0045277;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;organelle envelope#GO:0031967;membrane protein complex#GO:0098796 oxidase#PC00175;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115322213|UniProtKB=A0ACM8EH97 A0ACM8EH97 LOC115322213 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8032269|UniProtKB=A0ACM8FHL9 A0ACM8FHL9 LOC8032269 PTHR21242:SF0 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 10 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;SAGA complex#GO:0000124;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;peptidase complex#GO:1905368 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121048491|UniProtKB=A0ACM8FH80 A0ACM8FH80 LOC121048491 PTHR13459:SF1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1 E3 UBIQUITIN-PROTEIN LIGASE RNF220 ISOFORM X1-RELATED acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 IXOSC|EnsemblGenome=LOC115310982|UniProtKB=A0ACM8ESA5 A0ACM8ESA5 LOC115310982 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030452|UniProtKB=A0ACM8EBB0 A0ACM8EBB0 LOC8030452 PTHR24198:SF199 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN SERINE_THREONINE-PROTEIN PHOSPHATASE 6 REGULATORY ANKYRIN REPEAT SUBUNIT A ISOFORM X1 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8031096|UniProtKB=A0ACM8DXR3 A0ACM8DXR3 LOC8031096 PTHR46118:SF4 PROTEIN ABHD11 SN-1-SPECIFIC DIACYLGLYCEROL LIPASE ABHD11 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC121837335|UniProtKB=A0ACM8G2V4 A0ACM8G2V4 LOC121837335 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318290|UniProtKB=A0ACM8FY63 A0ACM8FY63 LOC115318290 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115319939|UniProtKB=A0ACM8G7J4 A0ACM8G7J4 LOC115319939 PTHR48575:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120851149|UniProtKB=A0ACM8G778 A0ACM8G778 PIG-M PTHR12886:SF0 PIG-M MANNOSYLTRANSFERASE GPI ALPHA-1,4-MANNOSYLTRANSFERASE I, CATALYTIC SUBUNIT mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organophosphate metabolic process#GO:0019637 endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mannosyltransferase complex#GO:0031501 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120841986|UniProtKB=A0ACM8EST8 A0ACM8EST8 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115330108|UniProtKB=A0ACM8EHT2 A0ACM8EHT2 LOC115330108 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845283|UniProtKB=A0ACM8FXF9 A0ACM8FXF9 LOC120845283 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8038802|UniProtKB=A0ACM8FB94 A0ACM8FB94 Schip1 PTHR13103:SF2 SCHWANNOMIN INTERACTING PROTEIN 1 IQCJ-SCHIP1 READTHROUGH TRANSCRIPT PROTEIN-RELATED regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 cellular anatomical structure#GO:0110165;cell junction#GO:0030054;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC8034767|UniProtKB=A0ACM8EG84 A0ACM8EG84 phtf PTHR12680:SF6 PUTATIVE HOMEODOMAIN TRANSCRIPTION FACTOR PHTF PROTEIN PHTF homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8032393|UniProtKB=A0ACM8EGX4 A0ACM8EGX4 Smurf PTHR11254:SF395 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SMURF1 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein metabolic process#GO:0019538;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;negative regulation of BMP signaling pathway#GO:0030514;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Activin beta signaling pathway#P06210>LACK#P06230;DPP signaling pathway#P06213>LACK#P06278;GBB signaling pathway#P06214>LACK#P06303;MYO signaling pathway#P06215>LACK#P06309;TGF-beta signaling pathway#P00052>Smurfs#P01279;ALP23B signaling pathway#P06209>LACK#P06219;SCW signaling pathway#P06216>LACK#P06321;BMP/activin signaling pathway-drosophila#P06211>Smurf#P06243;DPP-SCW signaling pathway#P06212>LACK#P06269 IXOSC|EnsemblGenome=LOC115309605|UniProtKB=A0ACM8DP14 A0ACM8DP14 LOC115309605 PTHR47456:SF1 PHD-TYPE DOMAIN-CONTAINING PROTEIN SI:DKEY-31C13.1 IXOSC|EnsemblGenome=LOC8027393|UniProtKB=A0ACM8DXP8 A0ACM8DXP8 LOC8027393 PTHR11937:SF607 ACTIN ACTIN-42A-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;cortical actin cytoskeleton organization#GO:0030866;cytoskeleton-dependent cytokinesis#GO:0061640;cell division#GO:0051301;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell cycle#GO:0007049;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Huntington disease#P00029>Actin#P00807 IXOSC|EnsemblGenome=LOC8032211|UniProtKB=A0ACM8ELT9 A0ACM8ELT9 PTHR17985:SF28 SER/THR-RICH PROTEIN T10 IN DGCR REGION TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG protein localization to extracellular region#GO:0071692;Golgi organization#GO:0007030;cellular component organization#GO:0016043;export from cell#GO:0140352;protein transport#GO:0015031;secretion by cell#GO:0032940;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;transport#GO:0006810;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120836051|UniProtKB=A0ACM8EMV2 A0ACM8EMV2 LOC120836051 PTHR47456:SF1 PHD-TYPE DOMAIN-CONTAINING PROTEIN SI:DKEY-31C13.1 IXOSC|EnsemblGenome=LOC8024059|UniProtKB=A0ACM8E5H4 A0ACM8E5H4 mib2 PTHR24202:SF4 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB2-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115315641|UniProtKB=A0ACM8DVJ1 A0ACM8DVJ1 LOC115315641 PTHR45782:SF4 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 1 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;ribosomal large subunit assembly#GO:0000027;cellular component assembly#GO:0022607;mitochondrial ribosome assembly#GO:0061668;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;mitochondrial large ribosomal subunit assembly#GO:1902775;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;protein-RNA complex assembly#GO:0022618 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115326568|UniProtKB=A0ACM8E766 A0ACM8E766 LOC115326568 PTHR16442:SF1 RING FINGER PROTEIN 17 RING FINGER PROTEIN 17 IXOSC|EnsemblGenome=LOC121838308|UniProtKB=A0ACM8G8N8 A0ACM8G8N8 LOC121838308 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8052677|UniProtKB=A0ACM8EX90 A0ACM8EX90 Eip63F-1 PTHR23048:SF66 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN 2 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115321334|UniProtKB=A0ACM8EQG6 A0ACM8EQG6 LOC121835553 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8029472|UniProtKB=A0ACM8FIH4 A0ACM8FIH4 Upf2 PTHR12839:SF7 NONSENSE-MEDIATED MRNA DECAY PROTEIN 2 UP-FRAMESHIFT SUPPRESSOR 2 REGULATOR OF NONSENSE TRANSCRIPTS 2 negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8039783|UniProtKB=A0ACM8EH88 A0ACM8EH88 LOC8039783 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8023169|UniProtKB=A0ACM8FK79 A0ACM8FK79 LOC8023169 PTHR22957:SF681 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 3 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC121832946|UniProtKB=A0ACM8FLL5 A0ACM8FLL5 LOC121832946 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120843209|UniProtKB=A0ACM8EVL3 A0ACM8EVL3 LOC120843209 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8050761|UniProtKB=A0ACM8ECY8 A0ACM8ECY8 LOC8050761 PTHR10288:SF358 KH DOMAIN CONTAINING RNA BINDING PROTEIN P-ELEMENT SOMATIC INHIBITOR, ISOFORM C nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of mRNA metabolic process#GO:1903311;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;mRNA processing#GO:0006397;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8023784|UniProtKB=A0ACM8EQW4 A0ACM8EQW4 LOC8023784 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040321|UniProtKB=A0ACM8DKH9 A0ACM8DKH9 LOC8040321 PTHR13195:SF0 PSEUDOURIDINE SYNTHASE-RELATED PSEUDOURIDYLATE SYNTHASE TRUB2, MITOCHONDRIAL isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;metabolic process#GO:0008152;mRNA modification#GO:0016556;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;RNA modification#GO:0009451;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of biosynthetic process#GO:0009891;macromolecule modification#GO:0043412;positive regulation of translation#GO:0045727 mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 lyase#PC00144 IXOSC|EnsemblGenome=LOC115324298|UniProtKB=A0ACM8EM46 A0ACM8EM46 LOC115328063 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848423|UniProtKB=A0ACM8FI67 A0ACM8FI67 LOC120848423 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8030869|UniProtKB=A0ACM8DHM2 A0ACM8DHM2 PTHR10507:SF0 CDC45-RELATED PROTEIN CELL DIVISION CONTROL PROTEIN 45 HOMOLOG DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688;binding#GO:0005488;single-stranded DNA binding#GO:0003697;chromatin binding#GO:0003682;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;recombinational repair#GO:0000725;double-strand break repair via break-induced replication#GO:0000727;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;cell cycle DNA replication#GO:0044786;DNA repair#GO:0006281;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;double-strand break repair#GO:0006302;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840 nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA replication preinitiation complex#GO:0031261;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 IXOSC|EnsemblGenome=LOC8050639|UniProtKB=A0ACM8G538 A0ACM8G538 LOC8050639 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8026403|UniProtKB=A0ACM8EAK9 A0ACM8EAK9 LOC8026403 PTHR45691:SF6 PROTEIN DIAPHANOUS PROTEIN DIAPHANOUS cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;actin polymerization or depolymerization#GO:0008154;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;actin filament polymerization#GO:0030041;actin cytoskeleton organization#GO:0030036;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029 cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin cytoskeleton#GO:0015629;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8051686|UniProtKB=A0ACM8FBV8 A0ACM8FBV8 LOC8051686 PTHR14038:SF0 BAT2 HLA-B-ASSOCIATED TRANSCRIPT 2 LP18708P RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8035928|UniProtKB=A0ACM8FCJ2 A0ACM8FCJ2 LOC8035928 PTHR12874:SF29 F-BOX ONLY PROTEIN 48-RELATED F-BOX ONLY PROTEIN 9 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120836390|UniProtKB=A0ACM8EFV8 A0ACM8EFV8 LOC120836390 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847701|UniProtKB=A0ACM8F4Q2 A0ACM8F4Q2 LOC120847701 PTHR11475:SF147 OXIDASE/PEROXIDASE PEROXIDASIN antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8035927|UniProtKB=A0ACM8FZH0 A0ACM8FZH0 Nthl1 PTHR43286:SF7 ENDONUCLEASE III-LIKE PROTEIN 1 ENDONUCLEASE III-LIKE PROTEIN 1 DNA N-glycosylase activity#GO:0019104;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;response to stress#GO:0006950;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 IXOSC|EnsemblGenome=LOC115332524|UniProtKB=A0ACM8EEP2 A0ACM8EEP2 Vps13D PTHR16166:SF141 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13D phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215 organelle organization#GO:0006996;macromolecule localization#GO:0033036;autophagy#GO:0006914;cellular process#GO:0009987;lipid transport#GO:0006869;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;macroautophagy#GO:0016236;metabolic process#GO:0008152;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;cellular component organization#GO:0016043;catabolic process#GO:0009056;lipid localization#GO:0010876;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;mitochondrion#GO:0005739;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;endosome#GO:0005768;endosome membrane#GO:0010008;organelle outer membrane#GO:0031968;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121832904|UniProtKB=A0ACM8FU99 A0ACM8FU99 LOC121832904 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115312219|UniProtKB=A0ACM8FXV4 A0ACM8FXV4 LOC115312219 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8032418|UniProtKB=A0ACM8DJH0 A0ACM8DJH0 Ih PTHR45689:SF5 I[[H]] CHANNEL, ISOFORM E I[[H]] CHANNEL, ISOFORM E voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8032346|UniProtKB=A0ACM8DJF3 A0ACM8DJF3 LOC8032346 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115332138|UniProtKB=A0ACM8EE65 A0ACM8EE65 LOC115332138 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200 IXOSC|EnsemblGenome=LOC115323620|UniProtKB=A0ACM8E3U2 A0ACM8E3U2 Pi4KIIIalpha PTHR10048:SF15 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE ALPHA transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 kinase#PC00137 IXOSC|EnsemblGenome=LOC8031141|UniProtKB=A0ACM8ENY3 A0ACM8ENY3 LOC8031141 PTHR10896:SF74 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE P glucuronosyltransferase activity#GO:0015020;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;glycoprotein biosynthetic process#GO:0009101;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115322051|UniProtKB=A0ACM8E2U9 A0ACM8E2U9 LOC115322051 PTHR10841:SF17 SYNAPSIN SYNAPSIN cytoskeletal adaptor activity#GO:0008093;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell junction#GO:0030054;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>Synapsin#P05775 IXOSC|EnsemblGenome=LOC8034033|UniProtKB=A0ACM8DQJ3 A0ACM8DQJ3 LOC8034033 PTHR43069:SF2 FUMARYLACETOACETASE FUMARYLACETOACETASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;phenol-containing compound metabolic process#GO:0018958;monocarboxylic acid catabolic process#GO:0072329;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 IXOSC|EnsemblGenome=LOC115330812|UniProtKB=A0ACM8FAK9 A0ACM8FAK9 LOC115330812 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115314577|UniProtKB=A0ACM8FYT4 A0ACM8FYT4 LOC115314577 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transporter#PC00227 IXOSC|EnsemblGenome=LOC115311936|UniProtKB=A0ACM8EIQ8 A0ACM8EIQ8 LOC115311936 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120845946|UniProtKB=A0ACM8F144 A0ACM8F144 LOC120845946 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033187|UniProtKB=A0ACM8E649 A0ACM8E649 PIG-Q PTHR21329:SF3 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q-RELATED PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT Q glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115318693|UniProtKB=A0ACM8FBE5 A0ACM8FBE5 LOC115318693 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120839527|UniProtKB=A0ACM8EMK2 A0ACM8EMK2 LOC120839527 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023777|UniProtKB=A0ACM8DPR4 A0ACM8DPR4 LOC8023777 PTHR46120:SF5 BETAINE--HOMOCYSTEINE S-METHYLTRANSFERASE 1 HCY-BINDING DOMAIN-CONTAINING PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115309530|UniProtKB=A0ACM8DNX4 A0ACM8DNX4 Membrin PTHR21230:SF1 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 2-RELATED protein binding#GO:0005515;SNAP receptor activity#GO:0005484;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090 membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;vesicle fusion#GO:0006906;organelle membrane fusion#GO:0090174;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050 coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;COPII-coated ER to Golgi transport vesicle#GO:0030134;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;transport vesicle#GO:0030133;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789 SNARE protein#PC00034;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120837467|UniProtKB=A0ACM8EI65 A0ACM8EI65 LOC120837467 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252 nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC120837598|UniProtKB=A0ACM8G2M5 A0ACM8G2M5 LOC120837598 PTHR24251:SF57 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120850015|UniProtKB=A0ACM8F9X0 A0ACM8F9X0 LOC120850015 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115332004|UniProtKB=A0ACM8EE22 A0ACM8EE22 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8035819|UniProtKB=A0ACM8F274 A0ACM8F274 Ranbp21 PTHR11223:SF3 EXPORTIN 1/5 EXPORTIN-5 RNA binding#GO:0003723;molecular carrier activity#GO:0140104;nucleic acid binding#GO:0003676;binding#GO:0005488;nucleocytoplasmic carrier activity#GO:0140142 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC8038022|UniProtKB=A0ACM8FCY7 A0ACM8FCY7 RhoGEF3 PTHR47544:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 4 SUBFAMILY NOT NAMED guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8038163|UniProtKB=A0ACM8F630 A0ACM8F630 LOC8038163 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8034620|UniProtKB=A0ACM8E7Z6 A0ACM8E7Z6 Tti1 PTHR18460:SF3 TEL2 INTERACTING PROTEIN 1 TTI1 FAMILY MEMBER TELO2-INTERACTING PROTEIN 1 HOMOLOG cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115308218|UniProtKB=A0ACM8DM56 A0ACM8DM56 LOC115308218 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120844470|UniProtKB=A0ACM8EYF8 A0ACM8EYF8 LOC120844470 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8037873|UniProtKB=A0ACM8EAX1 A0ACM8EAX1 DCTN5-p25 PTHR46126:SF1 DYNACTIN SUBUNIT 5 DYNACTIN SUBUNIT 5 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629 microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC121836014|UniProtKB=A0ACM8DKG0 A0ACM8DKG0 LOC8039851 PTHR45840:SF2 RHOMBOID-RELATED PROTEIN PROTEIN RHOMBOID-RELATED IXOSC|EnsemblGenome=LOC8026325|UniProtKB=A0ACM8DHN0 A0ACM8DHN0 Ufm1 PTHR15825:SF0 UBIQUITIN-FOLD MODIFIER 1 UBIQUITIN-FOLD MODIFIER 1 response to stress#GO:0006950;reticulophagy#GO:0061709;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;autophagy#GO:0006914;catabolic process#GO:0009056;response to stimulus#GO:0050896;macroautophagy#GO:0016236;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120839048|UniProtKB=A0ACM8EL51 A0ACM8EL51 LOC120839048 PTHR23430:SF50 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115329598|UniProtKB=A0ACM8E9V0 A0ACM8E9V0 LOC115329598 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115319294|UniProtKB=A0ACM8ESY1 A0ACM8ESY1 LOC115319294 PTHR37162:SF13 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849225|UniProtKB=A0ACM8F7E1 A0ACM8F7E1 LOC120849225 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8023655|UniProtKB=A0ACM8E1J0 A0ACM8E1J0 LOC8023655 PTHR15591:SF19 RUN AND SH3 DOMAIN CONTAINING RUN DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC115322874|UniProtKB=A0ACM8EEY7 A0ACM8EEY7 LOC115322874 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8033111|UniProtKB=A0ACM8FU12 A0ACM8FU12 DPCoAC PTHR24089:SF736 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL COENZYME A TRANSPORTER SLC25A42 organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 IXOSC|EnsemblGenome=LOC115314185|UniProtKB=A0ACM8DTY7 A0ACM8DTY7 LOC115314185 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8043092|UniProtKB=A0ACM8E060 A0ACM8E060 LOC8043092 PTHR13604:SF0 DC12-RELATED ABASIC SITE PROCESSING PROTEIN HMCES nucleic acid binding#GO:0003676;catalytic activity#GO:0003824;binding#GO:0005488;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;lyase activity#GO:0016829;DNA binding#GO:0003677 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;replication fork#GO:0005657;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8033995|UniProtKB=A0ACM8E1I7 A0ACM8E1I7 Rnb PTHR23312:SF8 ARMC5 ARMADILLO REPEAT-CONTAINING -RELATED ARMADILLO REPEAT-CONTAINING PROTEIN 5 anatomical structure development#GO:0048856;developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653 IXOSC|EnsemblGenome=LOC120843453|UniProtKB=A0ACM8EW83 A0ACM8EW83 LOC120843453 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8042062|UniProtKB=A0ACM8DKV1 A0ACM8DKV1 LOC8042062 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8042001|UniProtKB=A0ACM8DKU6 A0ACM8DKU6 LOC8042001 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8030359|UniProtKB=A0ACM8FM03 A0ACM8FM03 LOC8030359 PTHR10605:SF65 HEPARAN SULFATE SULFOTRANSFERASE GH20068P sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115318644|UniProtKB=A0ACM8EA18 A0ACM8EA18 LOC115318644 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8043249|UniProtKB=A0ACM8DL31 A0ACM8DL31 awd PTHR11349:SF116 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550 cellular process#GO:0009987;metabolic process#GO:0008152;phosphorus metabolic process#GO:0006793;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleoside triphosphate metabolic process#GO:0009141 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 transferase#PC00220;kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 IXOSC|EnsemblGenome=LOC8023932|UniProtKB=A0ACM8ENG2 A0ACM8ENG2 LOC8023932 PTHR11108:SF1 FERROCHELATASE FERROCHELATASE, MITOCHONDRIAL catalytic activity#GO:0003824;lyase activity#GO:0016829 pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779;cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lyase#PC00144 Heme biosynthesis#P02746>Ferrochelatase#P02972 IXOSC|EnsemblGenome=LOC8024602|UniProtKB=A0ACM8DIE6 A0ACM8DIE6 LOC8024602 PTHR12127:SF25 MUCOLIPIN SD02261P ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated calcium channel activity#GO:0099604;calcium ion transmembrane transporter activity#GO:0015085 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;cytoplasm#GO:0005737;vacuole#GO:0005773;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8042665|UniProtKB=A0ACM8DKZ6 A0ACM8DKZ6 LOC8042665 PTHR12493:SF0 CUE DOMAIN CONTAINING 2 CUE DOMAIN-CONTAINING PROTEIN 2 IXOSC|EnsemblGenome=LOC121834547|UniProtKB=A0ACM8FP05 A0ACM8FP05 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120839053|UniProtKB=A0ACM8FZH1 A0ACM8FZH1 LOC120839053 PTHR23428:SF386 HISTONE H2B HISTONE H2B 1-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115320940|UniProtKB=A0ACM8ETF4 A0ACM8ETF4 LOC115320940 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115328389|UniProtKB=A0ACM8FE71 A0ACM8FE71 LOC115328389 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332940|UniProtKB=A0ACM8G2W9 A0ACM8G2W9 LOC115332940 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115309160|UniProtKB=A0ACM8DNH8 A0ACM8DNH8 LOC115309160 PTHR35617:SF4 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN TYR RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043485|UniProtKB=A0ACM8DUJ0 A0ACM8DUJ0 twisted PTHR10050:SF46 DOLICHYL-PHOSPHATE-MANNOSE--PROTEIN MANNOSYLTRANSFERASE PROTEIN O-MANNOSYL-TRANSFERASE 2 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115328923|UniProtKB=A0ACM8G4M7 A0ACM8G4M7 LOC115328923 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8024875|UniProtKB=A0ACM8DIQ0 A0ACM8DIQ0 LOC8024875 PTHR23424:SF29 SERUM AMYLOID A SERUM AMYLOID A PROTEIN apolipoprotein#PC00052;transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8023945|UniProtKB=A0ACM8E1D0 A0ACM8E1D0 LOC8023945 PTHR10634:SF149 AN1-TYPE ZINC FINGER PROTEIN AN1-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115312856|UniProtKB=A0ACM8DSG7 A0ACM8DSG7 LOC115312856 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042742|UniProtKB=A0ACM8ESS5 A0ACM8ESS5 LOC8042742 PTHR23506:SF26 GH10249P MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8040821|UniProtKB=A0ACM8E9S9 A0ACM8E9S9 PTHR46014:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 TETRATRICOPEPTIDE REPEAT PROTEIN 1 IXOSC|EnsemblGenome=LOC120850395|UniProtKB=A0ACM8F8P4 A0ACM8F8P4 Exd2 PTHR13620:SF133 3-5 EXONUCLEASE EXONUCLEASE 3'-5' DOMAIN-CONTAINING PROTEIN 2 exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408 DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;RNA biosynthetic process#GO:0032774 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8034350|UniProtKB=A0ACM8DJ82 A0ACM8DJ82 RIOK1 PTHR45723:SF5 SERINE/THREONINE-PROTEIN KINASE RIO1 SERINE_THREONINE-PROTEIN KINASE RIO1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;preribosome#GO:0030684 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115311229|UniProtKB=A0ACM8DQK5 A0ACM8DQK5 LOC115311229 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115330253|UniProtKB=A0ACM8EAK2 A0ACM8EAK2 LOC115330253 PTHR24114:SF50 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74A IXOSC|EnsemblGenome=LOC8027589|UniProtKB=A0ACM8FCF5 A0ACM8FCF5 LOC8027589 PTHR11010:SF128 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8031643|UniProtKB=A0ACM8EKY6 A0ACM8EKY6 cbc PTHR12755:SF6 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYRIBONUCLEOTIDE 5'-HYDROXYL-KINASE CLP1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;phosphotransferase activity, alcohol group as acceptor#GO:0016773 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121835797|UniProtKB=A0ACM8FVU5 A0ACM8FVU5 LOC121835797 PTHR10472:SF5 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 1 catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 IXOSC|EnsemblGenome=LOC8033819|UniProtKB=A0ACM8DID2 A0ACM8DID2 LOC8033819 PTHR45971:SF1 PHOX (PX) DOMAIN-CONTAINING PROTEIN RUBICON, ISOFORM A binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115329272|UniProtKB=A0ACM8G6Q4 A0ACM8G6Q4 LOC115329272 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121835247|UniProtKB=A0ACM8FT06 A0ACM8FT06 LOC121835247 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8043426|UniProtKB=A0ACM8FEA6 A0ACM8FEA6 LOC8043426 PTHR46858:SF5 OS05G0521000 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE APD1-RELATED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 IXOSC|EnsemblGenome=LOC8035831|UniProtKB=A0ACM8FBT7 A0ACM8FBT7 Hr38 PTHR24085:SF4 NUCLEAR HORMONE RECEPTOR NUCLEAR HORMONE RECEPTOR HR38-RELATED binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;nuclear receptor binding#GO:0016922;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;transcription factor binding#GO:0008134;sequence-specific double-stranded DNA binding#GO:1990837 response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to nitrogen compound#GO:1901699 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 C4 zinc finger nuclear receptor#PC00169;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8054031|UniProtKB=A0ACM8DVY6 A0ACM8DVY6 LOC8054031 PTHR11559:SF370 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE-RELATED esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 IXOSC|EnsemblGenome=LOC8038037|UniProtKB=A0ACM8E6S7 A0ACM8E6S7 Epp PTHR16469:SF27 UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BA-RELATED UBIQUITIN-ASSOCIATED AND SH3 DOMAIN-CONTAINING BB-RELATED IXOSC|EnsemblGenome=LOC120849141|UniProtKB=A0ACM8F743 A0ACM8F743 LOC120849142 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC120841421|UniProtKB=A0ACM8ESL4 A0ACM8ESL4 LOC120841421 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8028706|UniProtKB=A0ACM8EPA4 A0ACM8EPA4 LOC8028706 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8039511|UniProtKB=A0ACM8DKE4 A0ACM8DKE4 LOC8039511 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 chloride transport#GO:0006821;transport#GO:0006810;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC115322145|UniProtKB=A0ACM8G135 A0ACM8G135 LOC115322145 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115331719|UniProtKB=A0ACM8EJN2 A0ACM8EJN2 LOC115331719 PTHR12606:SF141 SENTRIN/SUMO-SPECIFIC PROTEASE GH15225P-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protease#PC00190 IXOSC|EnsemblGenome=LOC115333090|UniProtKB=A0ACM8EEH7 A0ACM8EEH7 LOC115333090 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121833542|UniProtKB=A0ACM8FLR6 A0ACM8FLR6 LOC121833542 PTHR35617:SF4 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN TYR RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034468|UniProtKB=A0ACM8FZG5 A0ACM8FZG5 LOC8034468 PTHR15857:SF0 COMM DOMAIN CONTAINING PROTEIN 2 COMM DOMAIN-CONTAINING PROTEIN 2 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8040044|UniProtKB=A0ACM8DQL4 A0ACM8DQL4 PTHR45682:SF5 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138 negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 IXOSC|EnsemblGenome=LOC8023497|UniProtKB=A0ACM8E6K1 A0ACM8E6K1 LOC8023497 PTHR12459:SF27 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN 135 IXOSC|EnsemblGenome=LOC120840271|UniProtKB=A0ACM8EN28 A0ACM8EN28 LOC120840271 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115328415|UniProtKB=A0ACM8E926 A0ACM8E926 LOC115328415 PTHR43530:SF1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 QUEUINE TRNA-RIBOSYLTRANSFERASE CATALYTIC SUBUNIT 1 pentosyltransferase activity#GO:0016763;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;glycosyltransferase activity#GO:0016757 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115324242|UniProtKB=A0ACM8FDU1 A0ACM8FDU1 mRpS9 PTHR21569:SF47 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9M RNA binding#GO:0003723;structural molecule activity#GO:0005198;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120836208|UniProtKB=A0ACM8FCZ4 A0ACM8FCZ4 PTHR13005:SF4 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8052675|UniProtKB=A0ACM8EZC5 A0ACM8EZC5 PTHR11835:SF84 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT BETA, MITOCHONDRIAL oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8029778|UniProtKB=A0ACM8DQ29 A0ACM8DQ29 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC120844033|UniProtKB=A0ACM8EXN6 A0ACM8EXN6 LOC120844033 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;monocarboxylic acid biosynthetic process#GO:0072330 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115311919|UniProtKB=A0ACM8ESS6 A0ACM8ESS6 LOC115311919 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327414|UniProtKB=A0ACM8EL40 A0ACM8EL40 LOC115327414 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115325389|UniProtKB=A0ACM8EGU8 A0ACM8EGU8 IntS6 PTHR12957:SF2 DEAD/H BOX POLYPEPTIDE 26/DICE1-RELATED INTEGRATOR COMPLEX SUBUNIT 6 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nucleic acid biosynthetic process#GO:0141187;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC115310806|UniProtKB=A0ACM8FG22 A0ACM8FG22 LOC115310806 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120849243|UniProtKB=A0ACM8F7A8 A0ACM8F7A8 LOC120849243 PTHR37162:SF13 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023929|UniProtKB=A0ACM8DHR1 A0ACM8DHR1 LOC8023929 PTHR19991:SF2 L 2 01289 GH08893P IXOSC|EnsemblGenome=LOC120847940|UniProtKB=A0ACM8F4W7 A0ACM8F4W7 LOC120847940 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8027557|UniProtKB=A0ACM8E7U7 A0ACM8E7U7 LOC8027557 PTHR14382:SF1 MDM2-BINDING PROTEIN MDM2-BINDING PROTEIN positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;protein localization to kinetochore#GO:0034501;macromolecule localization#GO:0033036;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of mitotic cell cycle#GO:0045931;intracellular protein localization#GO:0008104;positive regulation of cell cycle G1/S phase transition#GO:1902808;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;localization#GO:0051179;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045 chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;condensed chromosome, centromeric region#GO:0000779;chromosome#GO:0005694;kinetochore#GO:0000776;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC120848768|UniProtKB=A0ACM8F6P8 A0ACM8F6P8 LOC120848768 PTHR16024:SF28 XK-RELATED PROTEIN XK-RELATED PROTEIN cell death#GO:0008219;programmed cell death#GO:0012501;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;anatomical structure development#GO:0048856;localization#GO:0051179;macromolecule localization#GO:0033036;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;transport#GO:0006810;developmental process#GO:0032502;phagocytosis#GO:0006909;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;cellular component organization#GO:0016043;endocytosis#GO:0006897;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane invagination#GO:0010324;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;apoptotic cell clearance#GO:0043277 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8052060|UniProtKB=A0ACM8DTB5 A0ACM8DTB5 LOC8052060 PTHR13063:SF10 ENOS INTERACTING PROTEIN NITRIC OXIDE SYNTHASE-INTERACTING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121047398|UniProtKB=A0ACM8G4C0 A0ACM8G4C0 LOC121047398 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8041820|UniProtKB=A0ACM8ENF0 A0ACM8ENF0 LOC8041820 PTHR43827:SF10 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE ZGC:110366 reductase#PC00198 IXOSC|EnsemblGenome=LOC121836064|UniProtKB=A0ACM8FXW2 A0ACM8FXW2 LOC121836064 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8041450|UniProtKB=A0ACM8E6I2 A0ACM8E6I2 Pp4-19C PTHR45619:SF8 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 IXOSC|EnsemblGenome=LOC121835662|UniProtKB=A0ACM8FW29 A0ACM8FW29 LOC121835662 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121045716|UniProtKB=A0ACM8FM61 A0ACM8FM61 LOC121045716 PTHR24351:SF110 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TORC1 signaling#GO:0038202;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Interleukin signaling pathway#P00036>p90RSK#P00964;PDGF signaling pathway#P00047>p90RSK#P01142 IXOSC|EnsemblGenome=LOC121838218|UniProtKB=A0ACM8G752 A0ACM8G752 LOC121838218 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030966|UniProtKB=A0ACM8DHU1 A0ACM8DHU1 LOC8030966 PTHR46388:SF2 NHL REPEAT-CONTAINING PROTEIN 2 NHL REPEAT-CONTAINING PROTEIN 2 IXOSC|EnsemblGenome=LOC8030549|UniProtKB=A0ACM8DZF6 A0ACM8DZF6 LOC8030549 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 IXOSC|EnsemblGenome=LOC115309660|UniProtKB=A0ACM8EN60 A0ACM8EN60 LOC115309660 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8024623|UniProtKB=A0ACM8E961 A0ACM8E961 Lsd-2 PTHR14024:SF49 PERILIPIN LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 1 regulation of localization#GO:0032879;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;lipid storage#GO:0019915;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8029063|UniProtKB=A0ACM8F7K3 A0ACM8F7K3 PTHR24241:SF117 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE S RECEPTOR-LIKE G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115311453|UniProtKB=A0ACM8F3Q0 A0ACM8F3Q0 LOC115311453 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8034339|UniProtKB=A0ACM8FI06 A0ACM8FI06 LOC8034339 PTHR14015:SF2 OPIOID GROWTH FACTOR RECEPTOR OGFR ZETA-TYPE OPIOID RECEPTOR OPIOID GROWTH FACTOR RECEPTOR (OGFR) CONSERVED DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115316526|UniProtKB=A0ACM8G4W4 A0ACM8G4W4 LOC115316526 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053362|UniProtKB=A0ACM8DLV0 A0ACM8DLV0 MESR6 PTHR13225:SF3 MISEXPRESSION SUPPRESSOR OF RAS 6 UPF0489 PROTEIN C5ORF22 IXOSC|EnsemblGenome=LOC8028277|UniProtKB=A0ACM8F8Q7 A0ACM8F8Q7 LOC8028277 PTHR24049:SF43 CRUMBS FAMILY MEMBER EGF-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC121837153|UniProtKB=A0ACM8G2I6 A0ACM8G2I6 LOC121837153 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042131|UniProtKB=A0ACM8F9P5 A0ACM8F9P5 LOC8042131 PTHR12675:SF6 MUSCLEBLIND-LIKE PROTEIN ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 10 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8039922|UniProtKB=A0ACM8F0I7 A0ACM8F0I7 LOC8039922 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8031570|UniProtKB=A0ACM8DZD9 A0ACM8DZD9 LOC8031570 PTHR24351:SF228 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120841257|UniProtKB=A0ACM8ERB0 A0ACM8ERB0 LOC120841257 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8028901|UniProtKB=A0ACM8DTB3 A0ACM8DTB3 LOC8028901 PTHR10185:SF17 PHOSPHOLIPASE D - RELATED GM01519P-RELATED phospholipase#PC00186 IXOSC|EnsemblGenome=LOC8032702|UniProtKB=A0ACM8ECH6 A0ACM8ECH6 LOC8032702 PTHR24161:SF130 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED TRANSIENT RECEPTOR POTENTIAL CHANNEL PYREXIA protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121046866|UniProtKB=A0ACM8FG23 A0ACM8FG23 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318195|UniProtKB=A0ACM8DXV6 A0ACM8DXV6 LOC115318195 PTHR11941:SF27 ENOYL-COA HYDRATASE-RELATED ETHYLMALONYL-COA DECARBOXYLASE carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 IXOSC|EnsemblGenome=LOC8039182|UniProtKB=A0ACM8E1Z6 A0ACM8E1Z6 EMC3 PTHR13116:SF5 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 3 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;EMC complex#GO:0072546;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC8025156|UniProtKB=A0ACM8DJ15 A0ACM8DJ15 LOC8025156 PTHR22851:SF0 U3 SMALL NUCLEOLAR RNA U3 SNORNA ASSOCIATED PROTEIN DDB1- AND CUL4-ASSOCIATED FACTOR 13 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8038946|UniProtKB=A0ACM8FSP4 A0ACM8FSP4 LOC8038946 PTHR19961:SF81 FIMBRIN/PLASTIN FI19014P1 actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;molecular adaptor activity#GO:0060090 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;actin filament bundle#GO:0032432;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115309138|UniProtKB=A0ACM8DNC3 A0ACM8DNC3 LOC115309138 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120850237|UniProtKB=A0ACM8FBP1 A0ACM8FBP1 LOC120850237 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320270|UniProtKB=A0ACM8E0N8 A0ACM8E0N8 LOC115320270 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120843252|UniProtKB=A0ACM8FLC0 A0ACM8FLC0 LOC120843252 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324777|UniProtKB=A0ACM8FYW7 A0ACM8FYW7 LOC115324777 PTHR39299:SF1 TRANSMEMBRANE PROTEIN DUF7789 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844769|UniProtKB=A0ACM8F0M5 A0ACM8F0M5 LOC120844769 PTHR31040:SF1 NURIM NURIM nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane#GO:0016020;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8025150|UniProtKB=A0ACM8F1K9 A0ACM8F1K9 LOC8025150 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115324954|UniProtKB=A0ACM8E4F3 A0ACM8E4F3 Pym PTHR22959:SF0 PYM PROTEIN PARTNER OF Y14 AND MAGO RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component disassembly#GO:0022411 nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115315566|UniProtKB=A0ACM8DVD7 A0ACM8DVD7 LOC115315566 PTHR20957:SF0 RNA-BINDING PROTEIN 48 RNA-BINDING PROTEIN 48 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654 IXOSC|EnsemblGenome=LOC115329210|UniProtKB=A0ACM8E997 A0ACM8E997 LOC115329210 PTHR10900:SF77 PERIOSTIN-RELATED FI19380P1 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120837724|UniProtKB=A0ACM8FT60 A0ACM8FT60 LOC120837724 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039667|UniProtKB=A0ACM8EDZ1 A0ACM8EDZ1 LOC8039667 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8025137|UniProtKB=A0ACM8EC35 A0ACM8EC35 cta PTHR10218:SF360 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT ALPHA HOMOLOG hydrolase activity, acting on acid anhydrides#GO:0016817;G protein-coupled receptor binding#GO:0001664;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;signaling receptor binding#GO:0005102;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515 cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cluster of actin-based cell projections#GO:0098862;side of membrane#GO:0098552;cell projection membrane#GO:0031253;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;apical plasma membrane#GO:0016324;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;apical part of cell#GO:0045177;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;brush border membrane#GO:0031526;plasma membrane region#GO:0098590;cell periphery#GO:0071944;brush border#GO:0005903;membrane#GO:0016020 G-protein#PC00020;heterotrimeric G-protein#PC00117 IXOSC|EnsemblGenome=LOC8030160|UniProtKB=A0ACM8DSB2 A0ACM8DSB2 LOC8030160 PTHR11200:SF311 INOSITOL 5-PHOSPHATASE SYNAPTOJANIN-1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;import into cell#GO:0098657;localization#GO:0051179;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;synaptic vesicle recycling#GO:0036465;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle endocytosis#GO:0048488 membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 Huntington disease#P00029>Synaptojanin#P00804 IXOSC|EnsemblGenome=LOC8026920|UniProtKB=A0ACM8DUS7 A0ACM8DUS7 LOC8026920 PTHR43866:SF3 MALONATE-SEMIALDEHYDE DEHYDROGENASE METHYLMALONATE-SEMIALDEHYDE_MALONATE-SEMIALDEHYDE DEHYDROGENASE [ACYLATING], MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;pyrimidine nucleobase catabolic process#GO:0006208;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleobase catabolic process#GO:0046113;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Pyrimidine Metabolism#P02771>Methylmalonate Semialdehyde Dehydrogenase#P03124 IXOSC|EnsemblGenome=LOC120836305|UniProtKB=A0ACM8EL34 A0ACM8EL34 LOC120836305 PTHR10609:SF28 BIOTINIDASE-RELATED CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8053382|UniProtKB=A0ACM8DLV1 A0ACM8DLV1 LOC8053382 PTHR15431:SF19 FGFR1 ONCOGENE PARTNER/LISH DOMAIN-CONTAINING PROTEIN CENTROSOMAL PROTEIN 20 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 intracellular organelle#GO:0043229;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;centrosome#GO:0005813;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC115308351|UniProtKB=A0ACM8EJA3 A0ACM8EJA3 LOC115308351 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312804|UniProtKB=A0ACM8EL92 A0ACM8EL92 LOC115312804 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120839689|UniProtKB=A0ACM8ESS1 A0ACM8ESS1 LOC120841960 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8043173|UniProtKB=A0ACM8FFH1 A0ACM8FFH1 LOC8043173 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8053768|UniProtKB=A0ACM8DLS5 A0ACM8DLS5 LOC8053768 PTHR11792:SF23 ARRESTIN PHOSRESTIN-1 protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 receptor internalization#GO:0031623;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;transport#GO:0006810;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;sensory perception#GO:0007600;nervous system process#GO:0050877;regulation of signaling#GO:0023051;localization#GO:0051179;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 Wnt signaling pathway#P00057>beta-arrestin#P01456 IXOSC|EnsemblGenome=LOC8040660|UniProtKB=A0ACM8E526 A0ACM8E526 p38b PTHR24055:SF615 MITOGEN-ACTIVATED PROTEIN KINASE MITOGEN-ACTIVATED PROTEIN KINASE P38A-RELATED catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;FGF signaling pathway#P00021>p38#P00644;TGF-beta signaling pathway#P00052>P38#P01275;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;EGF receptor signaling pathway#P00018>p38#P00562;Ras Pathway#P04393>p38#P04558;Oxidative stress response#P00046>p38#P01135;p53 pathway feedback loops 2#P04398>p38 MAPK#P04648;Parkinson disease#P00049>p38 MAPK#P01212 IXOSC|EnsemblGenome=LOC8026429|UniProtKB=A0ACM8EIJ2 A0ACM8EIJ2 LOC8026429 PTHR12606:SF141 SENTRIN/SUMO-SPECIFIC PROTEASE GH15225P-RELATED catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;post-translational protein modification#GO:0043687 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 protease#PC00190 IXOSC|EnsemblGenome=LOC8023451|UniProtKB=A0ACM8EBU8 A0ACM8EBU8 LOC8023451 PTHR24031:SF301 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX18 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC121837103|UniProtKB=A0ACM8G271 A0ACM8G271 LOC121837103 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026764|UniProtKB=A0ACM8FUS0 A0ACM8FUS0 LOC8026764 PTHR14189:SF0 PROTEIN PHOSPHATASE METHYLESTERASE-1 RELATED PROTEIN PHOSPHATASE METHYLESTERASE 1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8035127|UniProtKB=A0ACM8DJR6 A0ACM8DJR6 LOC8035127 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8029986|UniProtKB=A0ACM8EBQ7 A0ACM8EBQ7 LOC8029986 PTHR11699:SF310 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE (NAD(+)) oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;catabolic process#GO:0009056;aldehyde catabolic process#GO:0046185 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC115322206|UniProtKB=A0ACM8G183 A0ACM8G183 LOC115322206 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120849287|UniProtKB=A0ACM8F7F4 A0ACM8F7F4 LOC120849287 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316560|UniProtKB=A0ACM8F8W0 A0ACM8F8W0 LOC115316560 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC121835802|UniProtKB=A0ACM8FX07 A0ACM8FX07 LOC121835802 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120841603|UniProtKB=A0ACM8FF17 A0ACM8FF17 LOC120841603 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115314972|UniProtKB=A0ACM8DUN9 A0ACM8DUN9 LOC115314972 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051223|UniProtKB=A0ACM8EP84 A0ACM8EP84 LOC8051223 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8034493|UniProtKB=A0ACM8EWK5 A0ACM8EWK5 LanB2 PTHR10574:SF435 NETRIN/LAMININ-RELATED LAMININ SUBUNIT GAMMA-1 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;neuron differentiation#GO:0030182;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 IXOSC|EnsemblGenome=LOC115315071|UniProtKB=A0ACM8F3R3 A0ACM8F3R3 LOC115315071 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC115320836|UniProtKB=A0ACM8F3M7 A0ACM8F3M7 LOC115320836 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8052182|UniProtKB=A0ACM8G0W5 A0ACM8G0W5 LOC8052182 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121046912|UniProtKB=A0ACM8FF49 A0ACM8FF49 LOC121046912 PTHR24394:SF67 ZINC FINGER PROTEIN MYONEURIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8037133|UniProtKB=A0ACM8E404 A0ACM8E404 LOC8037133 PTHR10129:SF50 TRANSCRIPTION FACTOR MAF TRAFFIC JAM, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8043796|UniProtKB=A0ACM8E5Y8 A0ACM8E5Y8 LOC8043796 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121046009|UniProtKB=A0ACM8FDP8 A0ACM8FDP8 LOC121046009 PTHR23248:SF9 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;endomembrane system organization#GO:0010256;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;plasma membrane organization#GO:0007009;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;cellular component organization#GO:0016043 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120837410|UniProtKB=A0ACM8EHA7 A0ACM8EHA7 LOC120837410 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115322746|UniProtKB=A0ACM8E2D3 A0ACM8E2D3 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115323576|UniProtKB=A0ACM8EK15 A0ACM8EK15 LOC115323576 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120846717|UniProtKB=A0ACM8FYM9 A0ACM8FYM9 LOC120846717 PTHR45080:SF8 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE 1 ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424 IXOSC|EnsemblGenome=LOC115329420|UniProtKB=A0ACM8E9K6 A0ACM8E9K6 LOC115329420 PTHR24289:SF24 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 21-HYDROXYLASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497 primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;regulation of biological quality#GO:0065008 IXOSC|EnsemblGenome=LOC115308209|UniProtKB=A0ACM8DV67 A0ACM8DV67 LOC115308209 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115322756|UniProtKB=A0ACM8G1H9 A0ACM8G1H9 LOC115322756 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028961|UniProtKB=A0ACM8G7E9 A0ACM8G7E9 LOC8028961 PTHR47958:SF56 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX23-RELATED helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC120846295|UniProtKB=A0ACM8F1Z2 A0ACM8F1Z2 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838189|UniProtKB=A0ACM8EIR8 A0ACM8EIR8 LOC120838189 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115324801|UniProtKB=A0ACM8F9K7 A0ACM8F9K7 LOC115324801 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121834234|UniProtKB=A0ACM8FQI9 A0ACM8FQI9 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115330244|UniProtKB=A0ACM8G294 A0ACM8G294 LOC115330244 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115325350|UniProtKB=A0ACM8FHK2 A0ACM8FHK2 LOC115325350 PTHR12608:SF1 TRANSMEMBRANE PROTEIN HTP-1 RELATED DIVALENT CATION_PROTON ANTIPORTER TMEM165-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115332775|UniProtKB=A0ACM8EWE9 A0ACM8EWE9 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8036154|UniProtKB=A0ACM8EHH2 A0ACM8EHH2 PTHR16301:SF25 IMPACT-RELATED PROTEIN IMPACT regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;response to stress#GO:0006950;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;signaling#GO:0023052;regulation of translational initiation#GO:0006446;cellular response to stress#GO:0033554;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8026981|UniProtKB=A0ACM8DXF7 A0ACM8DXF7 ClC-b PTHR11689:SF169 CHLORIDE CHANNEL PROTEIN CLC FAMILY MEMBER H(+)_CL(-) EXCHANGE TRANSPORTER 7 monoatomic anion channel activity#GO:0005253;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;chloride channel activity#GO:0005254;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;vacuole#GO:0005773;cytoplasm#GO:0005737;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;monoatomic ion channel complex#GO:0034702;lysosomal membrane#GO:0005765;membrane#GO:0016020 ion channel#PC00133 IXOSC|EnsemblGenome=LOC120844506|UniProtKB=A0ACM8EYW7 A0ACM8EYW7 LOC120844506 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121838043|UniProtKB=A0ACM8G6B7 A0ACM8G6B7 LOC121838043 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031551|UniProtKB=A0ACM8E838 A0ACM8E838 Snapin PTHR31305:SF3 SNARE-ASSOCIATED PROTEIN SNAPIN SNARE-ASSOCIATED PROTEIN SNAPIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;vesicle localization#GO:0051648;vacuolar acidification#GO:0007035;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular transport#GO:0046907;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;vacuolar transport#GO:0007034;anterograde trans-synaptic signaling#GO:0098916;homeostatic process#GO:0042592;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;regulation of pH#GO:0006885;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of intracellular pH#GO:0051453;synaptic vesicle localization#GO:0097479;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport in synapse#GO:0099003;endosomal transport#GO:0016197;exocytosis#GO:0006887;regulated exocytosis#GO:0045055;chemical homeostasis#GO:0048878;establishment of organelle localization#GO:0051656;signaling#GO:0023052;export from cell#GO:0140352;intracellular monoatomic ion homeostasis#GO:0006873;regulation of biological process#GO:0050789;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;secretion by cell#GO:0032940;lysosomal transport#GO:0007041 cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;presynapse#GO:0098793;secretory vesicle#GO:0099503;intracellular protein-containing complex#GO:0140535;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;secretory granule#GO:0030141;BLOC-1 complex#GO:0031083;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 IXOSC|EnsemblGenome=LOC8052780|UniProtKB=A0ACM8FV82 A0ACM8FV82 LOC8052780 PTHR24366:SF140 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS KEKKON 1, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8026244|UniProtKB=A0ACM8FT89 A0ACM8FT89 LOC8026244 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120836163|UniProtKB=A0ACM8EM36 A0ACM8EM36 LOC120836163 PTHR24394:SF62 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115332966|UniProtKB=A0ACM8EE68 A0ACM8EE68 LOC115332966 PTHR18976:SF34 APOLIPOPROTEIN LIPID-BINDING PROTEIN apolipoprotein#PC00052;transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115311750|UniProtKB=A0ACM8ERA7 A0ACM8ERA7 LOC115311750 PTHR42693:SF47 ARYLSULFATASE FAMILY MEMBER N-ACETYLGALACTOSAMINE-6-SULFATASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8039939|UniProtKB=A0ACM8EK50 A0ACM8EK50 LOC8039939 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115310142|UniProtKB=A0ACM8EGY3 A0ACM8EGY3 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115325905|UniProtKB=A0ACM8E605 A0ACM8E605 LOC115325905 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8034195|UniProtKB=A0ACM8FTC4 A0ACM8FTC4 LOC8034195 PTHR24416:SF611 TYROSINE-PROTEIN KINASE RECEPTOR TYROSINE-PROTEIN KINASE TRANSMEMBRANE RECEPTOR ROR molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;phosphotransferase activity, alcohol group as acceptor#GO:0016773;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;protein kinase activity#GO:0004672;transferase activity#GO:0016740;kinase activity#GO:0016301;signaling receptor activity#GO:0038023 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8043887|UniProtKB=A0ACM8DL53 A0ACM8DL53 LOC8043887 PTHR47760:SF1 G-PROTEIN COUPLED RECEPTOR B0563.6-LIKE PROTEIN-RELATED G PROTEIN-COUPLED RECEPTOR B0563.6-RELATED transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8041086|UniProtKB=A0ACM8FSF2 A0ACM8FSF2 Sik3 PTHR24346:SF119 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE SIK3 HOMOLOG-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120843280|UniProtKB=A0ACM8FNX7 A0ACM8FNX7 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8028084|UniProtKB=A0ACM8EE85 A0ACM8EE85 LOC8028084 PTHR45620:SF42 PDF RECEPTOR-LIKE PROTEIN-RELATED G PROTEIN-COUPLED RECEPTOR SEB-2 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120845444|UniProtKB=A0ACM8FZ20 A0ACM8FZ20 LOC120845444 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115323459|UniProtKB=A0ACM8E3P7 A0ACM8E3P7 LOC115323459 PTHR45888:SF4 HL01030P-RELATED PHD ZINC FINGER FY-RICH DOMAIN AND SET DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 IXOSC|EnsemblGenome=LOC115308223|UniProtKB=A0ACM8F6M4 A0ACM8F6M4 LOC115312291 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120846559|UniProtKB=A0ACM8F3J2 A0ACM8F3J2 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8025171|UniProtKB=A0ACM8EEI5 A0ACM8EEI5 Dpm1 PTHR43398:SF1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 DOLICHOL-PHOSPHATE MANNOSYLTRANSFERASE SUBUNIT 1 hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8031673|UniProtKB=A0ACM8EXI9 A0ACM8EXI9 LOC8031673 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824 nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC8050451|UniProtKB=A0ACM8G755 A0ACM8G755 LOC8050451 PTHR45857:SF10 FORMIN-LIKE PROTEIN FORMIN-LIKE PROTEIN binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular process#GO:0009987;cell motility#GO:0048870;cell migration#GO:0016477 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8029980|UniProtKB=A0ACM8EA97 A0ACM8EA97 Patr-1 PTHR21551:SF0 TOPOISOMERASE II-ASSOCIATED PROTEIN PAT1 PROTEIN ASSOCIATED WITH TOPO II RELATED - 1, ISOFORM A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle assembly#GO:0070925;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;catabolic process#GO:0009056;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component assembly#GO:0022607;regulation of RNA stability#GO:0043487;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;P-body assembly#GO:0033962;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;negative regulation of protein metabolic process#GO:0051248;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;RNA destabilization#GO:0050779;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;P-body#GO:0000932;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA processing factor#PC00147;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115327910|UniProtKB=A0ACM8FY49 A0ACM8FY49 LOC121836286 PTHR23428:SF386 HISTONE H2B HISTONE H2B 1-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115313958|UniProtKB=A0ACM8FM74 A0ACM8FM74 LOC115313958 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319203|UniProtKB=A0ACM8F242 A0ACM8F242 LOC115319203 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8038704|UniProtKB=A0ACM8ECI9 A0ACM8ECI9 PTHR11920:SF335 GUANYLYL CYCLASE GUANYLATE CYCLASE lyase activity#GO:0016829;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824 cyclic nucleotide biosynthetic process#GO:0009190;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanylate cyclase#PC00114;lyase#PC00144 IXOSC|EnsemblGenome=LOC8044147|UniProtKB=A0ACM8E2X8 A0ACM8E2X8 LOC8044147 PTHR11758:SF16 40S RIBOSOMAL PROTEIN S15A SMALL RIBOSOMAL SUBUNIT PROTEIN US8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121834836|UniProtKB=A0ACM8FSI4 A0ACM8FSI4 LOC121834836 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC120839068|UniProtKB=A0ACM8FZL6 A0ACM8FZL6 LOC120839068 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115309384|UniProtKB=A0ACM8DNS8 A0ACM8DNS8 LOC115309384 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115333029|UniProtKB=A0ACM8EEA6 A0ACM8EEA6 LOC115333029 PTHR44145:SF5 DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL DNAJ HOMOLOG L(2)TID, MITOCHONDRIAL organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121837254|UniProtKB=A0ACM8G2K4 A0ACM8G2K4 LOC121837254 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8032967|UniProtKB=A0ACM8DMY5 A0ACM8DMY5 LOC8032967 PTHR12774:SF2 PEROXISOMAL BIOGENESIS FACTOR 19 PEROXISOMAL BIOGENESIS FACTOR 19 signal sequence receptor activity#GO:0005048 protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;peroxisomal transport#GO:0043574;protein transport#GO:0015031;peroxisome organization#GO:0007031;localization within membrane#GO:0051668;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120846355|UniProtKB=A0ACM8F1E1 A0ACM8F1E1 RhoGAP93B PTHR45876:SF8 FI04035P RHO GTPASE-ACTIVATING PROTEIN 39 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8026554|UniProtKB=A0ACM8FDP3 A0ACM8FDP3 LOC8026554 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051406|UniProtKB=A0ACM8E8B1 A0ACM8E8B1 LOC8051406 PTHR24161:SF132 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED SUBFAMILY NOT NAMED protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115310357|UniProtKB=A0ACM8EG80 A0ACM8EG80 LOC115310357 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829 biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC115325002|UniProtKB=A0ACM8E5H1 A0ACM8E5H1 LOC115325002 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030106|UniProtKB=A0ACM8FH04 A0ACM8FH04 LOC8030106 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8027898|UniProtKB=A0ACM8DWH8 A0ACM8DWH8 LOC8027898 PTHR10196:SF69 SUGAR KINASE GLYCEROL KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;acylglycerol metabolic process#GO:0006639;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;neutral lipid metabolic process#GO:0006638;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;organophosphate biosynthetic process#GO:0090407 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 carbohydrate kinase#PC00065;kinase#PC00137 IXOSC|EnsemblGenome=LOC8051271|UniProtKB=A0ACM8EI26 A0ACM8EI26 LOC8051271 PTHR12156:SF5 PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3 FI18040P1 IXOSC|EnsemblGenome=LOC8035197|UniProtKB=A0ACM8FYG2 A0ACM8FYG2 LOC8035197 PTHR23253:SF78 EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA EUKARYOTIC TRANSLATION INITIATION FACTOR 4G1, ISOFORM B-RELATED translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;translation initiation factor activity#GO:0003743;RNA binding#GO:0003723 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120842608|UniProtKB=A0ACM8EU58 A0ACM8EU58 LOC120842608 PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8031337|UniProtKB=A0ACM8DU75 A0ACM8DU75 LOC8031337 PTHR12429:SF6 NEURALIZED PROTEIN NEURALIZED acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;localization#GO:0051179;protein transport#GO:0015031;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of protein localization to organelle#GO:0072594;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;transport#GO:0006810;regulation of response to stimulus#GO:0048583 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8029114|UniProtKB=A0ACM8G7X7 A0ACM8G7X7 ckn PTHR24174:SF16 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 CASKIN-2 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8042315|UniProtKB=A0ACM8E807 A0ACM8E807 PTHR11431:SF75 FERRITIN FERRITIN ferrous iron binding#GO:0008198;iron ion binding#GO:0005506;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 storage protein#PC00210 IXOSC|EnsemblGenome=LOC8039415|UniProtKB=A0ACM8FHC5 A0ACM8FHC5 LOC8039415 PTHR43330:SF7 METHIONINE AMINOPEPTIDASE METHIONINE AMINOPEPTIDASE 1 metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120848982|UniProtKB=A0ACM8F5W4 A0ACM8F5W4 LOC8041223 PTHR11431:SF75 FERRITIN FERRITIN metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;iron ion binding#GO:0005506;ferrous iron binding#GO:0008198 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 storage protein#PC00210 IXOSC|EnsemblGenome=LOC8023523|UniProtKB=A0ACM8DH85 A0ACM8DH85 LOC8023523 PTHR24067:SF157 UBIQUITIN-CONJUGATING ENZYME E2 FI11905P transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein K48-linked ubiquitination#GO:0070936;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8051790|UniProtKB=A0ACM8EBE6 A0ACM8EBE6 LOC8051790 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8027301|UniProtKB=A0ACM8EYZ7 A0ACM8EYZ7 LOC8027301 PTHR11324:SF17 IL16-RELATED BIG BANG, ISOFORM C cytokine#PC00083;interleukin superfamily#PC00128 IXOSC|EnsemblGenome=LOC120839350|UniProtKB=A0ACM8ELX1 A0ACM8ELX1 LOC120839350 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121838003|UniProtKB=A0ACM8G5T2 A0ACM8G5T2 LOC121838003 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8030625|UniProtKB=A0ACM8DS60 A0ACM8DS60 Tbp PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN DNA-templated transcription initiation#GO:0006352;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;Huntington disease#P00029>TBP#P00779 IXOSC|EnsemblGenome=LOC115325356|UniProtKB=A0ACM8E154 A0ACM8E154 LOC115325356 PTHR12019:SF9 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN THYMOPOIETIN intercellular signal molecule#PC00207;peptide hormone#PC00179 IXOSC|EnsemblGenome=LOC115329089|UniProtKB=A0ACM8FFV3 A0ACM8FFV3 LOC115329089 PTHR23079:SF55 RNA-DEPENDENT RNA POLYMERASE RNA-DIRECTED RNA POLYMERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;siRNA processing#GO:0030422;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8037381|UniProtKB=A0ACM8F7S9 A0ACM8F7S9 LOC8037381 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120841271|UniProtKB=A0ACM8ERG5 A0ACM8ERG5 LOC120841271 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8027205|UniProtKB=A0ACM8DIT3 A0ACM8DIT3 LOC8027205 PTHR45704:SF18 RAS-LIKE FAMILY MEMBER 11 SMALL MONOMERIC GTPASE IXOSC|EnsemblGenome=LOC121833029|UniProtKB=A0ACM8FK39 A0ACM8FK39 LOC121833029 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC121833972|UniProtKB=A0ACM8FNT3 A0ACM8FNT3 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8041222|UniProtKB=A0ACM8EAV3 A0ACM8EAV3 LOC8041222 PTHR15323:SF6 D123 PROTEIN TRANSLATION INITIATION FACTOR EIF2 ASSEMBLY PROTEIN cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8036456|UniProtKB=A0ACM8EI21 A0ACM8EI21 PTHR22770:SF48 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 positive regulation of canonical NF-kappaB signal transduction#GO:0043123;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;protein metabolic process#GO:0019538;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120843561|UniProtKB=A0ACM8EWE5 A0ACM8EWE5 LOC120843561 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834554|UniProtKB=A0ACM8FQM2 A0ACM8FQM2 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052106|UniProtKB=A0ACM8FWD4 A0ACM8FWD4 LOC8052106 PTHR33643:SF1 UREASE ACCESSORY PROTEIN D UREASE ACCESSORY PROTEIN D enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 cellular process#GO:0009987;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 IXOSC|EnsemblGenome=LOC8031522|UniProtKB=A0ACM8F546 A0ACM8F546 LOC8031522 PTHR21028:SF2 SI:CH211-156B7.4 CYTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026803|UniProtKB=A0ACM8DYM2 A0ACM8DYM2 LOC8026803 PTHR10900:SF124 PERIOSTIN-RELATED FASCICLIN-1 cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8050712|UniProtKB=A0ACM8G1Q3 A0ACM8G1Q3 Hasp PTHR45656:SF24 PROTEIN CBR-CLEC-78 LOCOMOTION-RELATED PROTEIN HIKARU GENKI-RELATED IXOSC|EnsemblGenome=LOC8036930|UniProtKB=A0ACM8E099 A0ACM8E099 Marf PTHR10465:SF3 TRANSMEMBRANE GTPASE FZO1 TRANSMEMBRANE GTPASE MARF-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;mitochondrial fusion#GO:0008053;organelle organization#GO:0006996;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;mitochondrion localization#GO:0051646;organelle localization#GO:0051640 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968 IXOSC|EnsemblGenome=LOC8053425|UniProtKB=A0ACM8E4B6 A0ACM8E4B6 Prps PTHR10210:SF123 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER RIBOSE-PHOSPHATE PYROPHOSPHOKINASE 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 nucleotide kinase#PC00172;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037488|UniProtKB=A0ACM8E254 A0ACM8E254 LOC8037488 PTHR22874:SF1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 ACTIVATING MOLECULE IN BECN1-REGULATED AUTOPHAGY PROTEIN 1 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;cellular component organization#GO:0016043;catabolic process#GO:0009056;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8035331|UniProtKB=A0ACM8EBT3 A0ACM8EBT3 LOC8035331 PTHR10724:SF10 30S RIBOSOMAL PROTEIN S1 S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115321089|UniProtKB=A0ACM8E1H3 A0ACM8E1H3 LOC115321089 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 IXOSC|EnsemblGenome=LOC8037883|UniProtKB=A0ACM8EAA9 A0ACM8EAA9 LOC8037883 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120841916|UniProtKB=A0ACM8ESE3 A0ACM8ESE3 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120850401|UniProtKB=A0ACM8FA36 A0ACM8FA36 LOC120850401 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846759|UniProtKB=A0ACM8F408 A0ACM8F408 LOC120846759 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115312016|UniProtKB=A0ACM8DRG6 A0ACM8DRG6 LOC115312016 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120836321|UniProtKB=A0ACM8F1J4 A0ACM8F1J4 LOC120836321 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314181|UniProtKB=A0ACM8DU14 A0ACM8DU14 LOC115314181 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844478|UniProtKB=A0ACM8EZU7 A0ACM8EZU7 LOC120844478 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC121837743|UniProtKB=A0ACM8G694 A0ACM8G694 LOC121837743 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC115311607|UniProtKB=A0ACM8FD94 A0ACM8FD94 LOC115311607 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039991|UniProtKB=A0ACM8E496 A0ACM8E496 LOC8039991 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115328158|UniProtKB=A0ACM8E990 A0ACM8E990 LOC115328158 PTHR11177:SF144 CHITINASE CHITINASE chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;chitin metabolic process#GO:0006030;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC121833611|UniProtKB=A0ACM8FKL5 A0ACM8FKL5 LOC121833611 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8023902|UniProtKB=A0ACM8FVB0 A0ACM8FVB0 LOC8023902 PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;citrate transmembrane transporter activity#GO:0015137 tricarboxylic acid transport#GO:0006842;carboxylic acid transport#GO:0046942;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;organic acid transport#GO:0015849;citrate transport#GO:0015746;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8040335|UniProtKB=A0ACM8DUZ5 A0ACM8DUZ5 LOC8040335 PTHR46559:SF3 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 11 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE cell adhesion molecule binding#GO:0050839;phosphoric ester hydrolase activity#GO:0042578;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein tyrosine phosphatase activity#GO:0004725;protein binding#GO:0005515;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;receptor tyrosine kinase binding#GO:0030971;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;positive regulation of MAPK cascade#GO:0043410;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;ERBB signaling pathway#GO:0038127;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8028743|UniProtKB=A0ACM8DN43 A0ACM8DN43 LOC8028743 PTHR13363:SF5 RING FINGER AND SRY DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF123 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115331735|UniProtKB=A0ACM8ECG6 A0ACM8ECG6 LOC115331735 PTHR24057:SF82 GLYCOGEN SYNTHASE KINASE-3 ALPHA PROTEIN KINASE SHAGGY-RELATED catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cell communication#GO:0007154;regulation of microtubule-based process#GO:0032886;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of microtubule cytoskeleton organization#GO:0070507;negative regulation of signal transduction#GO:0009968;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;regulation of ubiquitin-dependent protein catabolic process#GO:2000058 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PDGF signaling pathway#P00047>GSK3#P01153;Angiogenesis#P00005>GSK3beta#P00211;Alzheimer disease-presenilin pathway#P00004>GSK-3beta#P00175 IXOSC|EnsemblGenome=LOC115327661|UniProtKB=A0ACM8ET17 A0ACM8ET17 LOC115327661 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121833325|UniProtKB=A0ACM8FKH7 A0ACM8FKH7 LOC121833325 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8034362|UniProtKB=A0ACM8FCK5 A0ACM8FCK5 PTHR44200:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 DNAJ HOMOLOG SUBFAMILY C MEMBER 7 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115324921|UniProtKB=A0ACM8E577 A0ACM8E577 LOC115324921 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846019|UniProtKB=A0ACM8F192 A0ACM8F192 LOC120846019 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843455|UniProtKB=A0ACM8EX97 A0ACM8EX97 LOC120843455 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847375|UniProtKB=A0ACM8F3Q2 A0ACM8F3Q2 LOC120847375 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8023210|UniProtKB=A0ACM8DX53 A0ACM8DX53 LOC8023210 PTHR11407:SF63 LYSOZYME C LYSOZYME lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8040416|UniProtKB=A0ACM8G2P0 A0ACM8G2P0 LOC8040416 PTHR23199:SF12 NEUROTROPHIN 1-RELATED NEUROTROPHIN 1 IXOSC|EnsemblGenome=LOC8032775|UniProtKB=A0ACM8FIG8 A0ACM8FIG8 LOC8032775 PTHR10037:SF230 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM CA[2+]-CHANNEL PROTEIN ALPHA[[1]] SUBUNIT T, ISOFORM F passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;sodium channel activity#GO:0005272;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 action potential#GO:0001508;calcium ion import#GO:0070509;biological regulation#GO:0065007;metal ion transport#GO:0030001;membrane depolarization#GO:0051899;transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;sodium channel complex#GO:0034706;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC115308414|UniProtKB=A0ACM8FA89 A0ACM8FA89 Imp PTHR10288:SF338 KH DOMAIN CONTAINING RNA BINDING PROTEIN IGF-II MRNA-BINDING PROTEIN, ISOFORM L RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA stabilization#GO:0043489;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;system development#GO:0048731;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115324099|UniProtKB=A0ACM8FQI2 A0ACM8FQI2 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115309595|UniProtKB=A0ACM8EPG1 A0ACM8EPG1 LOC115311196 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030035|UniProtKB=A0ACM8G441 A0ACM8G441 LOC8030035 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028544|UniProtKB=A0ACM8DXL4 A0ACM8DXL4 LOC8028544 PTHR11947:SF20 PYRUVATE DEHYDROGENASE KINASE BRANCHED-CHAIN ALPHA-KETOACID DEHYDROGENASE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216;regulation of carbohydrate metabolic process#GO:0006109;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120843938|UniProtKB=A0ACM8G8N5 A0ACM8G8N5 LOC120843938 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120837392|UniProtKB=A0ACM8EGT0 A0ACM8EGT0 LOC120837392 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121834762|UniProtKB=A0ACM8FRD4 A0ACM8FRD4 LOC121834762 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8036153|UniProtKB=A0ACM8DML7 A0ACM8DML7 PTHR43690:SF40 NARDILYSIN NARDILYSIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120845765|UniProtKB=A0ACM8F0T2 A0ACM8F0T2 LOC120845765 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047 transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8036376|UniProtKB=A0ACM8DJY9 A0ACM8DJY9 LOC8036376 PTHR23222:SF1 PROHIBITIN PROHIBITIN-2 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115327201|UniProtKB=A0ACM8EJP5 A0ACM8EJP5 LOC115327201 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120837618|UniProtKB=A0ACM8EHT7 A0ACM8EHT7 LOC120837618 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC8037062|UniProtKB=A0ACM8EKX8 A0ACM8EKX8 LOC8037062 PTHR23023:SF317 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836731|UniProtKB=A0ACM8G060 A0ACM8G060 LOC121836731 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC115321582|UniProtKB=A0ACM8F3E9 A0ACM8F3E9 LOC115321582 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8024952|UniProtKB=A0ACM8E5X9 A0ACM8E5X9 LOC8024952 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8029735|UniProtKB=A0ACM8FU96 A0ACM8FU96 LOC8029735 PTHR45655:SF13 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN guanylate cyclase#PC00114;cyclase#PC00079 IXOSC|EnsemblGenome=LOC8038060|UniProtKB=A0ACM8DIF7 A0ACM8DIF7 LOC8038060 PTHR45771:SF6 HOMEOTIC PROTEIN DEFORMED HOMEOTIC PROTEIN SEX COMBS REDUCED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;positive regulation of transcription by RNA polymerase II#GO:0045944;anterior/posterior pattern specification#GO:0009952;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;positive regulation of DNA-templated transcription#GO:0045893;pattern specification process#GO:0007389;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8043422|UniProtKB=A0ACM8E119 A0ACM8E119 LOC8043422 PTHR21637:SF0 BTB/POZ DOMAIN-CONTAINING PROTEIN 10-RELATED AT10158P cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8030068|UniProtKB=A0ACM8DMF0 A0ACM8DMF0 LOC8030068 PTHR43686:SF1 SULFURTRANSFERASE-RELATED AMINOTRAN_5 DOMAIN-CONTAINING PROTEIN metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8043455|UniProtKB=A0ACM8DYC2 A0ACM8DYC2 LOC8043455 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8034234|UniProtKB=A0ACM8EED1 A0ACM8EED1 LOC8034234 PTHR22752:SF3 G PROTEIN-COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 135 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115308579|UniProtKB=A0ACM8F6J1 A0ACM8F6J1 LOC115308579 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8052400|UniProtKB=A0ACM8DP92 A0ACM8DP92 kra PTHR14208:SF2 BASIC LEUCINE ZIPPER AND W2 DOMAIN-CONTAINING PROTEIN PROTEIN KRASAVIETZ intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC8043017|UniProtKB=A0ACM8E340 A0ACM8E340 LOC8043017 PTHR23511:SF34 SYNAPTIC VESICLE GLYCOPROTEIN 2 SYNAPTIC VESICLE GLYCOPROTEIN 2B ISOFORM X1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8052868|UniProtKB=A0ACM8DLY4 A0ACM8DLY4 LOC8052868 PTHR15813:SF9 SORTING NEXIN-22 AND 24 PX DOMAIN-CONTAINING PROTEIN phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120840933|UniProtKB=A0ACM8EQN2 A0ACM8EQN2 LOC120840933 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8028668|UniProtKB=A0ACM8E9X6 A0ACM8E9X6 LOC8028668 PTHR23331:SF1 CXYORF1 WASH COMPLEX SUBUNIT 1 actin filament-based process#GO:0030029;localization within membrane#GO:0051668;supramolecular fiber organization#GO:0097435;secretion by cell#GO:0032940;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;export from cell#GO:0140352;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;endocytic recycling#GO:0032456;transport#GO:0006810;intracellular transport#GO:0046907;exocytosis#GO:0006887;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;actin filament organization#GO:0007015;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192 intracellular vesicle#GO:0097708;vesicle#GO:0031982;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;recycling endosome#GO:0055037;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8042188|UniProtKB=A0ACM8EJI2 A0ACM8EJI2 LOC8042188 PTHR11567:SF25 ACID PHOSPHATASE-RELATED PROTEIN FRA10AC1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8050572|UniProtKB=A0ACM8ED08 A0ACM8ED08 Sil1 PTHR19316:SF35 PROTEIN FOLDING REGULATOR NUCLEOTIDE EXCHANGE FACTOR SIL1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC8051018|UniProtKB=A0ACM8DLD9 A0ACM8DLD9 LOC8051018 PTHR16083:SF54 LEUCINE RICH REPEAT CONTAINING PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 59 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120841835|UniProtKB=A0ACM8ES78 A0ACM8ES78 LOC120841835 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8031677|UniProtKB=A0ACM8EL60 A0ACM8EL60 LOC8031677 PTHR24365:SF555 TOLL-LIKE RECEPTOR MSTPROX-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120847689|UniProtKB=A0ACM8F4N8 A0ACM8F4N8 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8025501|UniProtKB=A0ACM8DVS7 A0ACM8DVS7 LOC8025501 PTHR12752:SF9 PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN KRAMER, ISOFORM I IXOSC|EnsemblGenome=LOC8042898|UniProtKB=A0ACM8FP40 A0ACM8FP40 PTHR22792:SF166 LUPUS LA PROTEIN-RELATED LUPUS LA PROTEIN HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8050663|UniProtKB=A0ACM8EC20 A0ACM8EC20 Task6 PTHR11003:SF359 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL DOMAIN-CONTAINING PROTEIN voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transport#GO:0006813;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC121048054|UniProtKB=A0ACM8FIG1 A0ACM8FIG1 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045842|UniProtKB=A0ACM8FV84 A0ACM8FV84 LOC121045842 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC8031267|UniProtKB=A0ACM8FPQ1 A0ACM8FPQ1 PTHR12431:SF14 SORTING NEXIN 17 AND 27 LD15323P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;metabolic process#GO:0008152;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810 early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121835127|UniProtKB=A0ACM8FSK1 A0ACM8FSK1 LOC121835127 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115311419|UniProtKB=A0ACM8FBI8 A0ACM8FBI8 dpa PTHR11630:SF66 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM4 ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;DNA repair#GO:0006281;nuclear DNA replication#GO:0033260;DNA metabolic process#GO:0006259;mitotic DNA replication#GO:1902969;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;double-strand break repair#GO:0006302;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cell cycle process#GO:0022402;cellular response to stimulus#GO:0051716;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;MCM complex#GO:0042555;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8027051|UniProtKB=A0ACM8DIM0 A0ACM8DIM0 LOC8027051 PTHR10657:SF4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8023558|UniProtKB=A0ACM8ECF8 A0ACM8ECF8 KrT95D PTHR13280:SF17 PHOSPHOFURIN ACIDIC CLUSTER SORTING PROTEIN KRUEPPEL TARGET AT 95D, ISOFORM A cellular process#GO:0009987;localization within membrane#GO:0051668;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179 IXOSC|EnsemblGenome=LOC115315903|UniProtKB=A0ACM8F2V9 A0ACM8F2V9 LOC115315903 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8023505|UniProtKB=A0ACM8DH80 A0ACM8DH80 LOC8023505 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120838079|UniProtKB=A0ACM8G8X3 A0ACM8G8X3 LOC120838079 PTHR45992:SF12 EUKARYOTIC ELONGATION FACTOR 2 KINASE-RELATED EUKARYOTIC ELONGATION FACTOR 2 KINASE calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;neuron to neuron synapse#GO:0098984;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization#GO:0099572;postsynaptic density#GO:0014069;cell junction#GO:0030054 Oxidative stress response#P00046>eEF2K#P01127;p38 MAPK pathway#P05918>eEF2K#P06022 IXOSC|EnsemblGenome=LOC8026914|UniProtKB=A0ACM8DIK0 A0ACM8DIK0 LOC8026914 PTHR13233:SF0 MICROSPHERULE PROTEIN 1 MICROSPHERULE PROTEIN 1 regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;NSL complex#GO:0044545;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromatin#GO:0000785;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC120845947|UniProtKB=A0ACM8F204 A0ACM8F204 LOC120845947 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330007|UniProtKB=A0ACM8ENE7 A0ACM8ENE7 LOC115330007 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121834880|UniProtKB=A0ACM8FS52 A0ACM8FS52 LOC121834880 PTHR45712:SF36 AGAP008170-PA PODOCAN ISOFORM X1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8024090|UniProtKB=A0ACM8DZ73 A0ACM8DZ73 Atf6 PTHR46164:SF3 ATF6, ISOFORM C ATF6, ISOFORM C cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of macromolecule biosynthetic process#GO:0010556;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;response to unfolded protein#GO:0006986;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383 IXOSC|EnsemblGenome=LOC120848223|UniProtKB=A0ACM8F5N8 A0ACM8F5N8 LOC120848223 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8025637|UniProtKB=A0ACM8DTC3 A0ACM8DTC3 LOC8025637 PTHR24329:SF585 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC115328381|UniProtKB=A0ACM8E7Z9 A0ACM8E7Z9 LOC115328381 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8040047|UniProtKB=A0ACM8DQU4 A0ACM8DQU4 PTHR24270:SF62 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED CD320 ANTIGEN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 apolipoprotein#PC00052;transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120847832|UniProtKB=A0ACM8F4R9 A0ACM8F4R9 RpL24-like PTHR10792:SF8 60S RIBOSOMAL PROTEIN L24 RIBOSOME BIOGENESIS PROTEIN RLP24-RELATED cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8040322|UniProtKB=A0ACM8E9W2 A0ACM8E9W2 LOC8040322 PTHR24314:SF20 NON-SPECIFIC LIPID TRANSFER PROTEIN-RELATED STEROL CARRIER PROTEIN 2 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121837306|UniProtKB=A0ACM8G4H3 A0ACM8G4H3 LOC121837306 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8031526|UniProtKB=A0ACM8DIC2 A0ACM8DIC2 ND-B18 PTHR20900:SF0 NADH:UBIQUINONE OXIDOREDUCTASE B18-LIKE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 7 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8024783|UniProtKB=A0ACM8FM06 A0ACM8FM06 LOC8024783 PTHR11851:SF149 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT BETA hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;endopeptidase complex#GO:1905369;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;peptidase complex#GO:1905368;membrane-enclosed lumen#GO:0031974 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8050514|UniProtKB=A0ACM8DLC3 A0ACM8DLC3 ref(2)P PTHR15090:SF0 SEQUESTOSOME 1-RELATED SEQUESTOSOME-1 binding#GO:0005488;modification-dependent protein binding#GO:0140030;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;polyubiquitin modification-dependent protein binding#GO:0031593 endosome organization#GO:0007032;process utilizing autophagic mechanism#GO:0061919;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;macroautophagy#GO:0016236;endomembrane system organization#GO:0010256;catabolic process#GO:0009056;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization#GO:0016043;organelle organization#GO:0006996 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115313968|UniProtKB=A0ACM8EJ71 A0ACM8EJ71 Rap1 PTHR24070:SF459 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAP1 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;response to nitrogen compound#GO:1901698;regulation of exocytosis#GO:0017157;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of secretion#GO:0051046;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;negative regulation of cellular process#GO:0048523;signaling#GO:0023052;regulation of synaptic vesicle exocytosis#GO:2000300;response to stimulus#GO:0050896;regulation of neurotransmitter secretion#GO:0046928;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of secretion by cell#GO:1903530;response to oxygen-containing compound#GO:1901700;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of neurotransmitter transport#GO:0051588;intracellular signaling cassette#GO:0141124;response to chemical#GO:0042221;regulation of trans-synaptic signaling#GO:0099177;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of transport#GO:0051049;regulation of localization#GO:0032879 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 Integrin signalling pathway#P00034>Rap1#P00906;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Rap1#P00703;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Rap1#P00734 IXOSC|EnsemblGenome=LOC8040414|UniProtKB=A0ACM8F273 A0ACM8F273 LOC8040414 PTHR23199:SF18 NEUROTROPHIN 1-RELATED PROTEIN SPAETZLE-RELATED protein binding#GO:0005515;molecular function activator activity#GO:0140677;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 developmental process#GO:0032502;defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;response to external stimulus#GO:0009605;innate immune response#GO:0045087;multicellular organism development#GO:0007275;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;nervous system development#GO:0007399;defense response to other organism#GO:0098542;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;central nervous system development#GO:0007417;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 Toll pathway-drosophila#P06217>SPZ#P06349;Toll pathway-drosophila#P06217>SPZ full length#P06347 IXOSC|EnsemblGenome=LOC115324721|UniProtKB=A0ACM8E4Y7 A0ACM8E4Y7 LOC115324721 PTHR28562:SF1 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 COP9 SIGNALOSOME COMPLEX SUBUNIT 9 IXOSC|EnsemblGenome=LOC8028195|UniProtKB=A0ACM8EDJ1 A0ACM8EDJ1 LOC8028195 PTHR19327:SF0 GOLGIN GOLGIN SUBFAMILY A MEMBER 4 protein binding#GO:0005515;small GTPase binding#GO:0031267;binding#GO:0005488;enzyme binding#GO:0019899 Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8031411|UniProtKB=A0ACM8G0X4 A0ACM8G0X4 LOC8031411 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC121047795|UniProtKB=A0ACM8FQ33 A0ACM8FQ33 LOC121047795 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC115331018|UniProtKB=A0ACM8EC19 A0ACM8EC19 LOC115331018 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121046243|UniProtKB=A0ACM8FCC2 A0ACM8FCC2 LOC121046243 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024638|UniProtKB=A0ACM8DII1 A0ACM8DII1 LOC8024638 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121833988|UniProtKB=A0ACM8FNK0 A0ACM8FNK0 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120837130|UniProtKB=A0ACM8FZT8 A0ACM8FZT8 LOC120837130 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041020|UniProtKB=A0ACM8DRQ3 A0ACM8DRQ3 LOC8041020 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8051780|UniProtKB=A0ACM8E6R6 A0ACM8E6R6 LOC8051780 PTHR12375:SF47 RNA-BINDING PROTEIN LUC7-RELATED LUC7-LIKE PROTEIN 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115326650|UniProtKB=A0ACM8E6X4 A0ACM8E6X4 LOC115326650 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310651|UniProtKB=A0ACM8DQ70 A0ACM8DQ70 LOC115310651 PTHR44086:SF14 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED RHODANESE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transferase#PC00220 IXOSC|EnsemblGenome=LOC120838500|UniProtKB=A0ACM8EKY5 A0ACM8EKY5 LOC120838500 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8039085|UniProtKB=A0ACM8EKM5 A0ACM8EKM5 LOC8039085 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8052101|UniProtKB=A0ACM8EGY9 A0ACM8EGY9 LOC8052101 PTHR31386:SF2 UNCHARACTERIZED PROTEIN KIAA2013 RIKEN CDNA 2510039O18 GENE LIKE IXOSC|EnsemblGenome=LOC120841003|UniProtKB=A0ACM8EQC0 A0ACM8EQC0 LOC120841003 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120842237|UniProtKB=A0ACM8EUE7 A0ACM8EUE7 LOC120842237 PTHR12101:SF1 POPEYE DOMAIN CONTAINING PROTEIN BVES anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 developmental process#GO:0032502;striated muscle cell differentiation#GO:0051146;multicellular organism development#GO:0007275;animal organ development#GO:0048513;cellular developmental process#GO:0048869;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;heart development#GO:0007507;multicellular organismal process#GO:0032501;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;muscle cell differentiation#GO:0042692;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle structure development#GO:0061061 tight junction#GO:0070160;cell junction#GO:0030054;sarcolemma#GO:0042383;anchoring junction#GO:0070161;apical junction complex#GO:0043296;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC8042327|UniProtKB=A0ACM8ESY2 A0ACM8ESY2 LOC8042327 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120837676|UniProtKB=A0ACM8EI25 A0ACM8EI25 LOC120837676 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8027755|UniProtKB=A0ACM8E5N2 A0ACM8E5N2 LOC8027755 PTHR11804:SF84 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED SACCHAROLYSIN catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8053109|UniProtKB=A0ACM8DM07 A0ACM8DM07 PTHR12300:SF161 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8026208|UniProtKB=A0ACM8ER05 A0ACM8ER05 LOC8026208 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT AT04468P-RELATED ATPase activator activity#GO:0001671;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 monoatomic ion transport#GO:0006811;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121837586|UniProtKB=A0ACM8G536 A0ACM8G536 LOC121837586 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8041851|UniProtKB=A0ACM8F4Z2 A0ACM8F4Z2 LOC8041851 PTHR12377:SF2 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2A macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC115308991|UniProtKB=A0ACM8EYK8 A0ACM8EYK8 LOC115308991 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847966|UniProtKB=A0ACM8F591 A0ACM8F591 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835434|UniProtKB=A0ACM8FT98 A0ACM8FT98 LOC121835434 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120845968|UniProtKB=A0ACM8F133 A0ACM8F133 LOC120845968 PTHR19855:SF11 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 HOMOLOG IXOSC|EnsemblGenome=LOC8039254|UniProtKB=A0ACM8FRG9 A0ACM8FRG9 LOC8039254 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC binding#GO:0005488;chromatin binding#GO:0003682 negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC121047503|UniProtKB=A0ACM8FEZ9 A0ACM8FEZ9 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033515|UniProtKB=A0ACM8FLR9 A0ACM8FLR9 SMC5 PTHR45916:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 5 nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 condensed chromosome#GO:0000793;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115319506|UniProtKB=A0ACM8EP96 A0ACM8EP96 LOC115319506 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 IXOSC|EnsemblGenome=LOC8053086|UniProtKB=A0ACM8E882 A0ACM8E882 LOC8053086 PTHR16524:SF2 CELL DEATH REGULATOR AVEN CELL DEATH REGULATOR AVEN regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic cell cycle#GO:0045930;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523 IXOSC|EnsemblGenome=LOC120845214|UniProtKB=A0ACM8F193 A0ACM8F193 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037827|UniProtKB=A0ACM8DI87 A0ACM8DI87 LOC8037827 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837807|UniProtKB=A0ACM8EHV0 A0ACM8EHV0 LOC120837807 PTHR22692:SF26 MYOSIN VII, XV SH3 DOMAIN-CONTAINING PROTEIN actin binding motor protein#PC00040 IXOSC|EnsemblGenome=LOC121838427|UniProtKB=A0ACM8DK75 A0ACM8DK75 LOC8038577 PTHR10263:SF5 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 16 KDA PROTEOLIPID SUBUNIT C membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC8024495|UniProtKB=A0ACM8EB87 A0ACM8EB87 LOC8024495 PTHR42944:SF1 ADENINE DNA GLYCOSYLASE ADENINE DNA GLYCOSYLASE nucleic acid binding#GO:0003676;binding#GO:0005488;DNA N-glycosylase activity#GO:0019104;DNA binding#GO:0003677;hydrolase activity#GO:0016787;double-stranded DNA binding#GO:0003690;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;damaged DNA binding#GO:0003684;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097 DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;mismatch repair#GO:0006298;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 IXOSC|EnsemblGenome=LOC115312794|UniProtKB=A0ACM8G6T5 A0ACM8G6T5 LOC115312794 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120851029|UniProtKB=A0ACM8FBC5 A0ACM8FBC5 Mer PTHR23281:SF39 MERLIN/MOESIN/EZRIN/RADIXIN MOESIN_EZRIN_RADIXIN HOMOLOG 2 cytoskeletal protein binding#GO:0008092;cell adhesion molecule binding#GO:0050839;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cell population proliferation#GO:0008285;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of organelle assembly#GO:1902115;positive regulation of transport#GO:0051050;regulation of anatomical structure morphogenesis#GO:0022603;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of cell population proliferation#GO:0042127;regulation of protein localization#GO:0032880;regulation of biological quality#GO:0065008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;filopodium#GO:0030175;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;actin-based cell projection#GO:0098858;membraneless organelle#GO:0043228;cell junction#GO:0030054;adherens junction#GO:0005912;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8043789|UniProtKB=A0ACM8FI65 A0ACM8FI65 LOC8043789 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8039113|UniProtKB=A0ACM8DKA7 A0ACM8DKA7 PTHR19359:SF14 CYTOCHROME B5 CYTOCHROME B5 heme binding#GO:0020037;binding#GO:0005488;tetrapyrrole binding#GO:0046906 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;membrane#GO:0016020 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8052522|UniProtKB=A0ACM8DNL1 A0ACM8DNL1 LOC8052522 PTHR11214:SF314 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8051847|UniProtKB=A0ACM8DLX2 A0ACM8DLX2 Uev1A PTHR24068:SF143 UBIQUITIN-CONJUGATING ENZYME E2 GEO06356P1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 response to stimulus#GO:0050896;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Uev1A#P01376 IXOSC|EnsemblGenome=LOC8029972|UniProtKB=A0ACM8FTD2 A0ACM8FTD2 Ptp69D PTHR19134:SF495 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE 69D catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;cell communication#GO:0007154;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;biological regulation#GO:0065007;neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502 protein modifying enzyme#PC00260;protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC115327819|UniProtKB=A0ACM8E7E1 A0ACM8E7E1 LOC115327819 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047977|UniProtKB=A0ACM8FFX9 A0ACM8FFX9 LOC121047977 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8025279|UniProtKB=A0ACM8F1I7 A0ACM8F1I7 LOC8025279 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120844639|UniProtKB=A0ACM8EZ97 A0ACM8EZ97 LOC120844639 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120842442|UniProtKB=A0ACM8ETV4 A0ACM8ETV4 LOC120842442 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120843711|UniProtKB=A0ACM8G377 A0ACM8G377 LOC120843711 PTHR43272:SF116 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE 1 ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;long-chain fatty acid metabolic process#GO:0001676;monocarboxylic acid metabolic process#GO:0032787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 ligase#PC00142 IXOSC|EnsemblGenome=LOC8039815|UniProtKB=A0ACM8E1E8 A0ACM8E1E8 LOC8039815 PTHR11668:SF300 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 protein phosphatase#PC00195 Dopamine receptor mediated signaling pathway#P05912>Protein Phosphatase-1#P05969;Nicotine pharmacodynamics pathway#P06587>PPP1CA#P06602 IXOSC|EnsemblGenome=LOC121834875|UniProtKB=A0ACM8FRQ3 A0ACM8FRQ3 LOC121834875 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8023706|UniProtKB=A0ACM8EE74 A0ACM8EE74 LOC8023706 PTHR12726:SF0 CERAMIDE GLUCOSYLTRANSFERASE CERAMIDE GLUCOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251 glycosphingolipid biosynthetic process#GO:0006688;glycolipid biosynthetic process#GO:0009247;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 membrane#GO:0016020;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC121833281|UniProtKB=A0ACM8FK57 A0ACM8FK57 LOC121833281 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8033815|UniProtKB=A0ACM8EH29 A0ACM8EH29 LOC8033815 PTHR11822:SF44 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;purine nucleotide metabolic process#GO:0006163;NADP+ metabolic process#GO:0006739;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;peroxisome#GO:0005777;mitochondrion#GO:0005739;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120846923|UniProtKB=A0ACM8F4E4 A0ACM8F4E4 LOC120846923 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8032839|UniProtKB=A0ACM8DR04 A0ACM8DR04 PTHR20873:SF0 L-SERYL-TRNA(SEC) KINASE L-SERYL-TRNA(SEC) KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488 IXOSC|EnsemblGenome=LOC8043417|UniProtKB=A0ACM8DYV8 A0ACM8DYV8 LOC8043417 PTHR11412:SF171 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN-LIKE ISOFORM X1 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 extracellular region#GO:0005576;catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120843857|UniProtKB=A0ACM8EY27 A0ACM8EY27 LOC120843857 PTHR19818:SF157 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN 84-LIKE double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8026667|UniProtKB=A0ACM8FXT2 A0ACM8FXT2 LOC8026667 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8041452|UniProtKB=A0ACM8DKM8 A0ACM8DKM8 LOC8041452 PTHR13806:SF46 FLOTILLIN-RELATED FLOTILLIN-2 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC115311701|UniProtKB=A0ACM8ELW9 A0ACM8ELW9 LOC115311701 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115309671|UniProtKB=A0ACM8FGX6 A0ACM8FGX6 LOC115309671 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8027782|UniProtKB=A0ACM8DSU5 A0ACM8DSU5 LOC8027782 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115321912|UniProtKB=A0ACM8E2P0 A0ACM8E2P0 LOC115321912 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115312773|UniProtKB=A0ACM8FZD0 A0ACM8FZD0 LOC115312773 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8035397|UniProtKB=A0ACM8G6N9 A0ACM8G6N9 LOC8035397 PTHR12400:SF21 INOSITOL POLYPHOSPHATE KINASE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793 kinase#PC00137 IXOSC|EnsemblGenome=LOC8030374|UniProtKB=A0ACM8DGV6 A0ACM8DGV6 LOC8030374 PTHR21219:SF3 FI19613P1 FI19613P1 IXOSC|EnsemblGenome=LOC120847273|UniProtKB=A0ACM8FNM9 A0ACM8FNM9 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 reproductive process#GO:0022414;homologous recombination#GO:0035825;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974;response to stimulus#GO:0050896;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8039524|UniProtKB=A0ACM8DKB7 A0ACM8DKB7 LOC8039524 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8038901|UniProtKB=A0ACM8DK90 A0ACM8DK90 LOC8038901 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8035677|UniProtKB=A0ACM8FV35 A0ACM8FV35 LOC8035677 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203 IXOSC|EnsemblGenome=LOC121045580|UniProtKB=A0ACM8FBJ2 A0ACM8FBJ2 LOC121045580 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8032947|UniProtKB=A0ACM8DVI9 A0ACM8DVI9 LOC8032947 PTHR18916:SF82 DYNACTIN 1-RELATED MICROTUBULE-BINDING CAP-GLY DOMAIN-CONTAINING PROTEIN microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 microtubule-based process#GO:0007017;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoplasmic microtubule organization#GO:0031122 nucleus#GO:0005634;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;microtubule end#GO:1990752;cell cortex#GO:0005938;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;microtubule#GO:0005874 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120844611|UniProtKB=A0ACM8F061 A0ACM8F061 unc79 PTHR21696:SF2 PROTEIN UNC-79 HOMOLOG PROTEIN UNC-79 HOMOLOG IXOSC|EnsemblGenome=LOC8029345|UniProtKB=A0ACM8E219 A0ACM8E219 LOC8029345 PTHR24351:SF234 RIBOSOMAL PROTEIN S6 KINASE SERINE_THREONINE-PROTEIN KINASE YPK2_YKR2 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120848907|UniProtKB=A0ACM8FQT9 A0ACM8FQT9 LOC120848907 PTHR41142:SF1 SI:DKEY-16J16.4 SI:DKEY-16J16.4 multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;signal transduction#GO:0007165;system development#GO:0048731;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;regulation of biological process#GO:0050789;peripheral nervous system development#GO:0007422 IXOSC|EnsemblGenome=LOC8034705|UniProtKB=A0ACM8ELV6 A0ACM8ELV6 LOC8034705 PTHR24115:SF472 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3A protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular localization#GO:0051641;localization#GO:0051179;anterograde axonal transport#GO:0008089;cilium organization#GO:0044782;axonal transport#GO:0098930;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;axo-dendritic transport#GO:0008088;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810 intracellular organelle#GO:0043229;microtubule#GO:0005874;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC121046478|UniProtKB=A0ACM8FF15 A0ACM8FF15 LOC121046478 PTHR10612:SF63 APOLIPOPROTEIN D APOLIPOPROTEIN D response to oxygen-containing compound#GO:1901700;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;response to chemical#GO:0042221;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 apolipoprotein#PC00052 IXOSC|EnsemblGenome=LOC115327389|UniProtKB=A0ACM8E8F4 A0ACM8E8F4 LOC115327389 PTHR21142:SF2 SARCOGLYCANS BETA-SARCOGLYCAN membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;sarcolemma#GO:0042383 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC120836101|UniProtKB=A0ACM8FNQ6 A0ACM8FNQ6 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC115331500|UniProtKB=A0ACM8F882 A0ACM8F882 LOC115331500 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031851|UniProtKB=A0ACM8FST5 A0ACM8FST5 LOC8031851 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 IXOSC|EnsemblGenome=LOC8032827|UniProtKB=A0ACM8FDI0 A0ACM8FDI0 PTHR12566:SF19 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB TRANSLATIONAL REGULATOR ORB2 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;translation factor activity#GO:0180051;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182 multicellular organismal reproductive process#GO:0048609;negative regulation of translation#GO:0017148;sexual reproduction#GO:0019953;reproductive process#GO:0022414;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;gamete generation#GO:0007276;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;spermatogenesis#GO:0007283;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;male gamete generation#GO:0048232;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417 neuron projection#GO:0043005;nucleus#GO:0005634;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular organelle#GO:0043229;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC120840196|UniProtKB=A0ACM8FVR0 A0ACM8FVR0 LOC120840196 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8024944|UniProtKB=A0ACM8F950 A0ACM8F950 LOC8024944 PTHR24189:SF80 MYOTROPHIN ANKYRIN REPEAT AND SOCS BOX PROTEIN 6-LIKE membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8041956|UniProtKB=A0ACM8DKT9 A0ACM8DKT9 LOC8041956 PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120837043|UniProtKB=A0ACM8EHE6 A0ACM8EHE6 LOC120837043 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8051136|UniProtKB=A0ACM8DQR1 A0ACM8DQR1 LOC8051136 PTHR12894:SF51 CNH DOMAIN CONTAINING TRANSFORMING GROWTH FACTOR-BETA RECEPTOR-ASSOCIATED PROTEIN 1 cellular component organization#GO:0016043;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle fusion#GO:0006906;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC121045887|UniProtKB=A0ACM8FB82 A0ACM8FB82 LOC121045887 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8051289|UniProtKB=A0ACM8DGL0 A0ACM8DGL0 LOC8051289 PTHR24248:SF212 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR DOPAMINE RECEPTOR 2 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 IXOSC|EnsemblGenome=LOC120836242|UniProtKB=A0ACM8ENU6 A0ACM8ENU6 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8043022|UniProtKB=A0ACM8E0L9 A0ACM8E0L9 LOC8043022 PTHR12630:SF1 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA-RELATED cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115308321|UniProtKB=A0ACM8G6H7 A0ACM8G6H7 LOC115308321 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8032265|UniProtKB=A0ACM8DS92 A0ACM8DS92 LOC8032265 PTHR31703:SF2 UPF0669 PROTEIN C6ORF120 UPF0669 PROTEIN C6ORF120 IXOSC|EnsemblGenome=LOC120844018|UniProtKB=A0ACM8EYK0 A0ACM8EYK0 LOC120844018 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC121833857|UniProtKB=A0ACM8FNK3 A0ACM8FNK3 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678 cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8036454|UniProtKB=A0ACM8EA72 A0ACM8EA72 LOC8036454 PTHR13402:SF6 RGPR-RELATED SECRETORY 16, ISOFORM I endoplasmic reticulum#GO:0005783;endoplasmic reticulum exit site#GO:0070971;ER to Golgi transport vesicle membrane#GO:0012507;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662 IXOSC|EnsemblGenome=LOC121836692|UniProtKB=A0ACM8G0K7 A0ACM8G0K7 LOC121836692 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120836821|UniProtKB=A0ACM8EFY9 A0ACM8EFY9 LOC120836821 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8027842|UniProtKB=A0ACM8DJD1 A0ACM8DJD1 LOC8027842 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115330672|UniProtKB=A0ACM8F5V2 A0ACM8F5V2 LOC115330672 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8052170|UniProtKB=A0ACM8DLI6 A0ACM8DLI6 LOC8052170 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120850760|UniProtKB=A0ACM8FBP0 A0ACM8FBP0 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8027432|UniProtKB=A0ACM8DVU3 A0ACM8DVU3 HPS1 PTHR12761:SF2 HERMANSKY-PUDLAK SYNDROME PROTEIN 1 GH27401P nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8043806|UniProtKB=A0ACM8DNT0 A0ACM8DNT0 PTHR11717:SF7 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC115329354|UniProtKB=A0ACM8FSB3 A0ACM8FSB3 LOC115329354 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8041206|UniProtKB=A0ACM8DNM8 A0ACM8DNM8 LOC8041206 PTHR45780:SF2 ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE ETHANOLAMINE-PHOSPHATE CYTIDYLYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;biosynthetic process#GO:0009058;phospholipid metabolic process#GO:0006644 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836443|UniProtKB=A0ACM8FYT0 A0ACM8FYT0 LOC121836443 PTHR46289:SF21 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842346|UniProtKB=A0ACM8FRM9 A0ACM8FRM9 LOC120842346 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8030453|UniProtKB=A0ACM8DH51 A0ACM8DH51 LOC8030453 PTHR19854:SF1 TRANSDUCIN BETA-LIKE 3 GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-LIKE PROTEIN 1 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027688|UniProtKB=A0ACM8G2D1 A0ACM8G2D1 LOC8027688 PTHR12101:SF1 POPEYE DOMAIN CONTAINING PROTEIN BVES small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;multicellular organismal process#GO:0032501;heart development#GO:0007507;biological regulation#GO:0065007;developmental process#GO:0032502;cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;striated muscle cell differentiation#GO:0051146 bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;sarcolemma#GO:0042383;cell junction#GO:0030054;tight junction#GO:0070160;anchoring junction#GO:0070161;apical junction complex#GO:0043296 IXOSC|EnsemblGenome=LOC8031941|UniProtKB=A0ACM8E7E3 A0ACM8E7E3 PTHR21100:SF9 PREFOLDIN SUBUNIT 4 PREFOLDIN SUBUNIT 4 biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8024578|UniProtKB=A0ACM8EBJ6 A0ACM8EBJ6 PTHR46022:SF1 PROTEIN PATCHED PROTEIN PATCHED protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;signaling receptor binding#GO:0005102;binding#GO:0005488;G protein-coupled receptor binding#GO:0001664;transmembrane signaling receptor activity#GO:0004888 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cell communication#GO:0010648 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 Hedgehog signaling pathway#P00025>Patched#P00689 IXOSC|EnsemblGenome=LOC115328853|UniProtKB=A0ACM8FF04 A0ACM8FF04 LOC115328853 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8050858|UniProtKB=A0ACM8FAZ7 A0ACM8FAZ7 LOC8050858 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8036955|UniProtKB=A0ACM8FWM8 A0ACM8FWM8 LOC8036955 PTHR24399:SF70 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121833321|UniProtKB=A0ACM8FKH3 A0ACM8FKH3 LOC121833321 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8033413|UniProtKB=A0ACM8DQQ9 A0ACM8DQQ9 LOC8033413 PTHR13019:SF25 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 GOLGI APPARATUS MEMBRANE PROTEIN TVP23 HOMOLOG establishment of protein localization#GO:0045184;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;macromolecule localization#GO:0033036;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;localization#GO:0051179;protein secretion#GO:0009306;secretion#GO:0046903;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8029079|UniProtKB=A0ACM8EAD6 A0ACM8EAD6 LOC8029079 PTHR11177:SF144 CHITINASE CHITINASE catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052353|UniProtKB=A0ACM8DZI1 A0ACM8DZI1 Non2 PTHR13844:SF53 SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY D LD45195P nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115310367|UniProtKB=A0ACM8EHP8 A0ACM8EHP8 LOC115310367 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838116|UniProtKB=A0ACM8EK16 A0ACM8EK16 LOC120838116 PTHR13370:SF3 RNA METHYLASE-RELATED TRNA (GUANINE(10)-N(2))-METHYLTRANSFERASE TRMT11 transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8040981|UniProtKB=A0ACM8DYZ8 A0ACM8DYZ8 LOC8040981 PTHR24168:SF21 KN MOTIF AND ANKYRIN REPEAT DOMAIN-CONTAINING KANK, ISOFORM D cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of anatomical structure size#GO:0090066;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular process#GO:0050794;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of actin filament length#GO:0030832;negative regulation of protein polymerization#GO:0032272;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;regulation of biological quality#GO:0065008 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC121833863|UniProtKB=A0ACM8FPD2 A0ACM8FPD2 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;reproductive process#GO:0022414;homologous recombination#GO:0035825;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115326223|UniProtKB=A0ACM8G5Q2 A0ACM8G5Q2 LOC121837695 PTHR11353:SF23 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT BETA protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 IXOSC|EnsemblGenome=LOC120836191|UniProtKB=A0ACM8F4G1 A0ACM8F4G1 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8053388|UniProtKB=A0ACM8DTW6 A0ACM8DTW6 LOC8053388 PTHR11662:SF465 SOLUTE CARRIER FAMILY 17 SIALIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115308934|UniProtKB=A0ACM8F5E4 A0ACM8F5E4 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311815|UniProtKB=A0ACM8DRA2 A0ACM8DRA2 LOC115311815 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034622|UniProtKB=A0ACM8E7Y8 A0ACM8E7Y8 eEF5 PTHR11673:SF6 TRANSLATION INITIATION FACTOR 5A FAMILY MEMBER EUKARYOTIC TRANSLATION INITIATION FACTOR 5A translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC115318740|UniProtKB=A0ACM8DYD4 A0ACM8DYD4 LOC115318740 PTHR11829:SF388 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN CROCODILE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC120844346|UniProtKB=A0ACM8EZJ1 A0ACM8EZJ1 LOC120844346 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120843394|UniProtKB=A0ACM8EVV4 A0ACM8EVV4 LOC120843394 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8030169|UniProtKB=A0ACM8E5C6 A0ACM8E5C6 LOC8030169 PTHR24036:SF5 SKELETOR-RELATED THROMBOMODULIN transmembrane signal receptor#PC00197 Blood coagulation#P00011>Thrombomodulin#P00457 IXOSC|EnsemblGenome=LOC120846322|UniProtKB=A0ACM8F1C0 A0ACM8F1C0 LOC120846322 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8038051|UniProtKB=A0ACM8FF22 A0ACM8FF22 LOC8038051 PTHR45659:SF24 HOMEOBOX PROTEIN HOX HOMEOTIC PROTEIN ANTENNAPEDIA-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;anterior/posterior pattern specification#GO:0009952;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;pattern specification process#GO:0007389 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8029720|UniProtKB=A0ACM8FJP4 A0ACM8FJP4 LOC8029720 PTHR33562:SF27 ATILLA, ISOFORM B-RELATED-RELATED FI02817P-RELATED IXOSC|EnsemblGenome=LOC8035694|UniProtKB=A0ACM8EBE9 A0ACM8EBE9 GckIII PTHR48012:SF10 STERILE20-LIKE KINASE, ISOFORM B-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8042942|UniProtKB=A0ACM8DL04 A0ACM8DL04 LOC8042942 PTHR24248:SF214 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TYRAMINE_OCTOPAMINE RECEPTOR G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115329402|UniProtKB=A0ACM8E9H1 A0ACM8E9H1 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043242|UniProtKB=A0ACM8E8D0 A0ACM8E8D0 Su(z)12 PTHR22597:SF0 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SUZ12 chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of cellular process#GO:0048523;constitutive heterochromatin formation#GO:0140719;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;DNA methylation-dependent constitutive heterochromatin formation#GO:0006346;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8035182|UniProtKB=A0ACM8E6W0 A0ACM8E6W0 LOC8035182 PTHR48070:SF6 ESTERASE OVCA2 ESTERASE OVCA2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 esterase#PC00097;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115323145|UniProtKB=A0ACM8F6H2 A0ACM8F6H2 LOC115323145 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC120846714|UniProtKB=A0ACM8FZX7 A0ACM8FZX7 LOC120846714 PTHR45080:SF8 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE 1 ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 synapse organization#GO:0050808;cell adhesion#GO:0007155;cellular component organization or biogenesis#GO:0071840;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;cell junction organization#GO:0034330 axon#GO:0030424;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8031085|UniProtKB=A0ACM8EMN4 A0ACM8EMN4 LOC8031085 PTHR24390:SF211 ZINC FINGER PROTEIN ZINC FINGER PROTEIN XFIN RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120840423|UniProtKB=A0ACM8FNY1 A0ACM8FNY1 LOC120840423 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120850368|UniProtKB=A0ACM8FAQ0 A0ACM8FAQ0 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8028686|UniProtKB=A0ACM8FH97 A0ACM8FH97 LOC8028686 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8038651|UniProtKB=A0ACM8DV90 A0ACM8DV90 LOC8038651 PTHR45943:SF1 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 E3 UBIQUITIN-PROTEIN LIGASE MYCBP2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;regulation of synapse organization#GO:0050807;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cell morphogenesis#GO:0000902;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;axon guidance#GO:0007411;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of synapse assembly#GO:0051963;regulation of cell junction assembly#GO:1901888;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of synapse structure or activity#GO:0050803;regulation of growth#GO:0040008;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120849893|UniProtKB=A0ACM8F8Q5 A0ACM8F8Q5 LOC120849893 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8025447|UniProtKB=A0ACM8FSY9 A0ACM8FSY9 LOC8025447 PTHR47327:SF23 FI18240P1-RELATED FI17836P1 anatomical structure development#GO:0048856;developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653 IXOSC|EnsemblGenome=LOC115318966|UniProtKB=A0ACM8DZ48 A0ACM8DZ48 LOC115318966 PTHR11096:SF0 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;cyclase activity#GO:0009975;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115313718|UniProtKB=A0ACM8EMI5 A0ACM8EMI5 LOC115320892 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8032586|UniProtKB=A0ACM8DZ69 A0ACM8DZ69 LOC8032586 PTHR10166:SF37 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED STOLID, ISOFORM H gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261 cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702 transporter#PC00227;voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC115331870|UniProtKB=A0ACM8F3T4 A0ACM8F3T4 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386 response to stimulus#GO:0050896;cell cycle process#GO:0022402;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;homologous recombination#GO:0035825;reproductive process#GO:0022414;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8026551|UniProtKB=A0ACM8EAY0 A0ACM8EAY0 LOC8026551 PTHR12027:SF77 WNT RELATED PROTEIN WNT-5 molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;protein binding#GO:0005515;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;system development#GO:0048731;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444;Cadherin signaling pathway#P00012>Wnt#P00474;Angiogenesis#P00005>Wnt#P00206 IXOSC|EnsemblGenome=LOC8043994|UniProtKB=A0ACM8EID4 A0ACM8EID4 LOC8043994 PTHR12147:SF22 METALLOPEPTIDASE M28 FAMILY MEMBER ENDOPLASMIC RETICULUM METALLOPEPTIDASE 1 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121834882|UniProtKB=A0ACM8FS58 A0ACM8FS58 LOC121834882 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029612|UniProtKB=A0ACM8DII4 A0ACM8DII4 LOC8029612 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115308352|UniProtKB=A0ACM8EYG5 A0ACM8EYG5 LOC115308352 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8026705|UniProtKB=A0ACM8E5L4 A0ACM8E5L4 LOC8026705 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121833103|UniProtKB=A0ACM8FJ90 A0ACM8FJ90 LOC8043036 PTHR12263:SF0 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC120841475|UniProtKB=A0ACM8FM92 A0ACM8FM92 LOC120841475 PTHR13948:SF3 RNA-BINDING PROTEIN FI21118P1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120836257|UniProtKB=A0ACM8EKS5 A0ACM8EKS5 LOC120836257 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8029421|UniProtKB=A0ACM8DI40 A0ACM8DI40 mTerf3 PTHR13068:SF112 CGI-12 PROTEIN-RELATED TRANSCRIPTION TERMINATION FACTOR 3, MITOCHONDRIAL biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;mitochondrial ribosome assembly#GO:0061668;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of metabolic process#GO:0009892;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115319901|UniProtKB=A0ACM8FT36 A0ACM8FT36 LOC115319901 PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 catabolic process#GO:0009056;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC115318837|UniProtKB=A0ACM8EWC6 A0ACM8EWC6 LOC115318837 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115311429|UniProtKB=A0ACM8DQZ7 A0ACM8DQZ7 LOC115311429 PTHR23149:SF9 G PATCH DOMAIN CONTAINING PROTEIN G PATCH DOMAIN-CONTAINING PROTEIN 4 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115323890|UniProtKB=A0ACM8EW04 A0ACM8EW04 LOC115323890 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC121046732|UniProtKB=A0ACM8FEP8 A0ACM8FEP8 LOC121046732 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052476|UniProtKB=A0ACM8EFI6 A0ACM8EFI6 LOC8052476 PTHR12245:SF12 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120836302|UniProtKB=A0ACM8FXY3 A0ACM8FXY3 LOC120836302 PTHR22600:SF59 BETA-HEXOSAMINIDASE BETA-HEXOSAMINIDASE A catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 glycosaminoglycan metabolic process#GO:0030203;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;lysosome#GO:0005764 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115316675|UniProtKB=A0ACM8FUY4 A0ACM8FUY4 LOC115316675 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8025980|UniProtKB=A0ACM8DGZ5 A0ACM8DGZ5 LOC8025980 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115325719|UniProtKB=A0ACM8EJZ1 A0ACM8EJZ1 LOC115325719 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120851154|UniProtKB=A0ACM8FB91 A0ACM8FB91 PTHR24228:SF63 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR MOODY signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120843747|UniProtKB=A0ACM8EXX4 A0ACM8EXX4 LOC120843747 PTHR10545:SF29 DIAMINE N-ACETYLTRANSFERASE GH14572P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;N-acetyltransferase activity#GO:0008080 acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC8040732|UniProtKB=A0ACM8DP81 A0ACM8DP81 LOC8040732 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313705|UniProtKB=A0ACM8DTC4 A0ACM8DTC4 LOC115313705 PTHR47501:SF5 TRANSPOSASE-RELATED BED-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115309305|UniProtKB=A0ACM8DNH7 A0ACM8DNH7 LOC115309305 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC121833885|UniProtKB=A0ACM8FBA7 A0ACM8FBA7 LOC8026682 PTHR46458:SF5 BLR2807 PROTEIN GLOBIN DOMAIN-CONTAINING PROTEIN molecular carrier activity#GO:0140104;small molecule binding#GO:0036094;binding#GO:0005488 response to stimulus#GO:0050896;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;establishment of localization#GO:0051234;localization#GO:0051179;response to hypoxia#GO:0001666;transport#GO:0006810 transporter#PC00227 IXOSC|EnsemblGenome=LOC8053400|UniProtKB=A0ACM8DLV4 A0ACM8DLV4 tsr PTHR11913:SF122 COFILIN-RELATED COFILIN_ACTIN-DEPOLYMERIZING FACTOR HOMOLOG-RELATED protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015 actin filament-based process#GO:0030029;protein-containing complex organization#GO:0043933;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;cellular component organization#GO:0016043;organelle organization#GO:0006996;protein depolymerization#GO:0051261;protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC8032599|UniProtKB=A0ACM8DQY0 A0ACM8DQY0 Xbp1 PTHR46542:SF1 X-BOX BINDING PROTEIN 1 X-BOX-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8035856|UniProtKB=A0ACM8DJW5 A0ACM8DJW5 LOC8035856 PTHR31493:SF1 NAZO FAMILY MEMBER PROTEIN C19ORF12 intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular process#GO:0009987;autophagy#GO:0006914;monoatomic ion homeostasis#GO:0050801;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;process utilizing autophagic mechanism#GO:0061919;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;catabolic process#GO:0009056 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8025358|UniProtKB=A0ACM8G0N5 A0ACM8G0N5 LOC8025358 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC120848460|UniProtKB=A0ACM8F4Y1 A0ACM8F4Y1 LOC120848460 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846563|UniProtKB=A0ACM8FNY4 A0ACM8FNY4 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular localization#GO:0051641;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;regulation of metabolic process#GO:0019222;protein localization to nucleus#GO:0034504;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;macromolecule localization#GO:0033036;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;membrane organization#GO:0061024;organelle localization#GO:0051640;localization within membrane#GO:0051668;localization#GO:0051179;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255 nuclear lumen#GO:0031981;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular organelle#GO:0043229 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC120841469|UniProtKB=A0ACM8ERK0 A0ACM8ERK0 RpS12 PTHR11843:SF0 40S RIBOSOMAL PROTEIN S12 SMALL RIBOSOMAL SUBUNIT PROTEIN ES12 metabolic process#GO:0008152;ribosome biogenesis#GO:0042254;ribosomal small subunit biogenesis#GO:0042274;translation#GO:0006412;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;cellular component biogenesis#GO:0044085;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;ribonucleoprotein complex biogenesis#GO:0022613 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121832860|UniProtKB=A0ACM8G0Q9 A0ACM8G0Q9 LOC121832860 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033589|UniProtKB=A0ACM8EJD2 A0ACM8EJD2 drongo PTHR46134:SF3 DRONGO, ISOFORM F DRONGO, ISOFORM F intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115316871|UniProtKB=A0ACM8F8Z4 A0ACM8F8Z4 LOC115316871 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842105|UniProtKB=A0ACM8EU64 A0ACM8EU64 PTHR24329:SF543 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN CEH-17 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;neuron differentiation#GO:0030182;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8028722|UniProtKB=A0ACM8DH64 A0ACM8DH64 LOC8028722 PTHR21184:SF6 MENORIN (DENDRITIC BRANCHING PROTEIN) MENORIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120845949|UniProtKB=A0ACM8F0E5 A0ACM8F0E5 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850716|UniProtKB=A0ACM8FAX0 A0ACM8FAX0 LOC120850716 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842257|UniProtKB=A0ACM8ETD9 A0ACM8ETD9 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115326380|UniProtKB=A0ACM8E5X6 A0ACM8E5X6 LOC115326380 PTHR43464:SF105 METHYLTRANSFERASE UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 ketone metabolic process#GO:0042180;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8023404|UniProtKB=A0ACM8FS20 A0ACM8FS20 LOC8023404 PTHR19290:SF147 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED HELIX-LOOP-HELIX PROTEIN DELILAH cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 sensory organ development#GO:0007423;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron projection development#GO:0031175;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron development#GO:0048666;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell development#GO:0048468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC121046644|UniProtKB=A0ACM8FEN6 A0ACM8FEN6 LOC121046644 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035963|UniProtKB=A0ACM8DUG9 A0ACM8DUG9 LOC8035963 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC121838232|UniProtKB=A0ACM8G8J5 A0ACM8G8J5 LOC121838232 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844017|UniProtKB=A0ACM8FH94 A0ACM8FH94 LOC120844017 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8039216|UniProtKB=A0ACM8E470 A0ACM8E470 LOC8039216 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC121834024|UniProtKB=A0ACM8FNN6 A0ACM8FNN6 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8031910|UniProtKB=A0ACM8G529 A0ACM8G529 LOC8031910 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC8026890|UniProtKB=A0ACM8DIJ9 A0ACM8DIJ9 LOC8026890 PTHR42698:SF1 GTPASE ERA GTPASE ERA, MITOCHONDRIAL membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;protein-RNA complex assembly#GO:0022618;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;ribosomal small subunit biogenesis#GO:0042274;protein-RNA complex organization#GO:0071826;ribosomal small subunit assembly#GO:0000028;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8035607|UniProtKB=A0ACM8FU56 A0ACM8FU56 Gycalpha99B PTHR45655:SF6 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 HEAD-SPECIFIC GUANYLATE CYCLASE lyase activity#GO:0016829;guanylate cyclase activity#GO:0004383;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849 response to stimulus#GO:0050896;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628 catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cyclase#PC00079;guanylate cyclase#PC00114 IXOSC|EnsemblGenome=LOC115330736|UniProtKB=A0ACM8G4Y0 A0ACM8G4Y0 LOC115330736 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050404|UniProtKB=A0ACM8FI01 A0ACM8FI01 LOC8050404 PTHR11022:SF80 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LC-RELATED peptidoglycan muralytic activity#GO:0061783;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023 response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to stimulus#GO:0050896;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742;response to external stimulus#GO:0009605;defense response#GO:0006952 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8027668|UniProtKB=A0ACM8G8R0 A0ACM8G8R0 nab PTHR12623:SF10 NGFI-A BINDING PROTEIN NGFI-A-BINDING PROTEIN HOMOLOG transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8035766|UniProtKB=A0ACM8G534 A0ACM8G534 LOC8035766 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115310876|UniProtKB=A0ACM8EG94 A0ACM8EG94 LOC115310876 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834690|UniProtKB=A0ACM8FPI1 A0ACM8FPI1 LOC8041379 PTHR12555:SF13 UBIQUITIN FUSION DEGRADATON PROTEIN 1 UBIQUITIN RECOGNITION FACTOR IN ER-ASSOCIATED DEGRADATION PROTEIN 1 polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488;protein binding#GO:0005515 protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC8051626|UniProtKB=A0ACM8E6S8 A0ACM8E6S8 PTHR19282:SF519 TETRASPANIN TETRASPANIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8051353|UniProtKB=A0ACM8DLU7 A0ACM8DLU7 LOC8051353 PTHR48011:SF4 CCR4-NOT TRANSCRIPTIONAL COMPLEX SUBUNIT CAF120-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 19 phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 IXOSC|EnsemblGenome=LOC121047748|UniProtKB=A0ACM8FGT5 A0ACM8FGT5 LOC121047748 PTHR13247:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 11 TPR REPEAT PROTEIN 11 MITOCHONDRIAL FISSION 1 PROTEIN lipid binding#GO:0008289;binding#GO:0005488 mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;organelle fission#GO:0048285;cellular component organization or biogenesis#GO:0071840;peroxisome organization#GO:0007031 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial membrane#GO:0031966;microbody#GO:0042579;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;peroxisomal membrane#GO:0005778;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8032835|UniProtKB=A0ACM8DNA2 A0ACM8DNA2 LOC8032835 PTHR23235:SF60 KRUEPPEL-LIKE TRANSCRIPTION FACTOR STRIPE, ISOFORM D RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8040951|UniProtKB=A0ACM8DGM0 A0ACM8DGM0 hay PTHR11274:SF0 RAD25/XP-B DNA REPAIR HELICASE GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE_TRANSLOCASE SUBUNIT XPB ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;isomerase activity#GO:0016853;3'-5' DNA helicase activity#GO:0043138;DNA helicase activity#GO:0003678;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352 RNA polymerase II, holoenzyme#GO:0016591;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nucleotide-excision repair complex#GO:0000109;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8041275|UniProtKB=A0ACM8EMK4 A0ACM8EMK4 LOC8041275 PTHR22883:SF147 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115308895|UniProtKB=A0ACM8EWX2 A0ACM8EWX2 LOC115308895 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847703|UniProtKB=A0ACM8FHW3 A0ACM8FHW3 LOC120847703 PTHR11475:SF147 OXIDASE/PEROXIDASE PEROXIDASIN antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120841451|UniProtKB=A0ACM8FJP1 A0ACM8FJP1 LOC120841451 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120839191|UniProtKB=A0ACM8G3D2 A0ACM8G3D2 LOC120839191 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120844663|UniProtKB=A0ACM8EZ69 A0ACM8EZ69 LOC120844663 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115318333|UniProtKB=A0ACM8DYN6 A0ACM8DYN6 LOC115318333 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8039679|UniProtKB=A0ACM8E6G2 A0ACM8E6G2 LOC8039679 PTHR14196:SF0 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 1 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;anatomical structure development#GO:0048856;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121835849|UniProtKB=A0ACM8FWU9 A0ACM8FWU9 LOC121835849 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121047185|UniProtKB=A0ACM8FFP8 A0ACM8FFP8 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115308683|UniProtKB=A0ACM8F961 A0ACM8F961 LOC115308683 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317493|UniProtKB=A0ACM8EVG8 A0ACM8EVG8 swm PTHR14398:SF0 RNA RECOGNITION RRM/RNP DOMAIN ZINC FINGER PROTEIN SWM binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115310292|UniProtKB=A0ACM8EJB8 A0ACM8EJB8 LOC115310292 PTHR10410:SF41 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED MPN DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 translation factor#PC00223;translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120849738|UniProtKB=A0ACM8F977 A0ACM8F977 LOC120849738 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293 monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;transport#GO:0006810;sodium ion transport#GO:0006814 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120841820|UniProtKB=A0ACM8ESI5 A0ACM8ESI5 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032208|UniProtKB=A0ACM8DJ86 A0ACM8DJ86 LOC8032208 PTHR28633:SF2 HERMANSKY-PUDLAK SYNDROME 3 PROTEIN HPS3 BIOGENESIS OF LYSOSOMAL ORGANELLES COMPLEX 2 SUBUNIT 1 IXOSC|EnsemblGenome=LOC120849128|UniProtKB=A0ACM8G0H3 A0ACM8G0H3 LOC120849128 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC121838154|UniProtKB=A0ACM8G6X7 A0ACM8G6X7 Cpr64Aa PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115323816|UniProtKB=A0ACM8E4J3 A0ACM8E4J3 IFT20 PTHR31978:SF2 INTRAFLAGELLAR TRANSPORT PROTEIN 20 HOMOLOG INTRAFLAGELLAR TRANSPORT 20 cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;organelle assembly#GO:0070925;localization#GO:0051179;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104 membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;centrosome#GO:0005813;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;cilium#GO:0005929;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 IXOSC|EnsemblGenome=LOC115318165|UniProtKB=A0ACM8EK84 A0ACM8EK84 LOC115318165 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8039582|UniProtKB=A0ACM8ECP4 A0ACM8ECP4 LOC8039582 PTHR11552:SF233 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI02019P catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120844498|UniProtKB=A0ACM8EYZ0 A0ACM8EYZ0 LOC120844498 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115324594|UniProtKB=A0ACM8E436 A0ACM8E436 LOC115324594 PTHR24078:SF586 DNAJ HOMOLOG SUBFAMILY C MEMBER DNAJ HOMOLOG SUBFAMILY B MEMBER 5 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8028313|UniProtKB=A0ACM8FNA4 A0ACM8FNA4 LOC8028313 PTHR23235:SF166 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR LUNA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120841914|UniProtKB=A0ACM8ETS3 A0ACM8ETS3 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121836735|UniProtKB=A0ACM8G148 A0ACM8G148 LOC121836735 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115310114|UniProtKB=A0ACM8DPI1 A0ACM8DPI1 LOC115310114 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC115316285|UniProtKB=A0ACM8F323 A0ACM8F323 LOC115316285 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8054019|UniProtKB=A0ACM8F690 A0ACM8F690 LOC8054019 PTHR12375:SF30 RNA-BINDING PROTEIN LUC7-RELATED RNA-BINDING PROTEIN ALSIN2-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA splicing, via transesterification reactions#GO:0000375;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;mRNA splice site recognition#GO:0006376;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;U2-type prespliceosome#GO:0071004;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8031934|UniProtKB=A0ACM8DIY2 A0ACM8DIY2 LOC8031934 PTHR43774:SF1 PEPTIDE METHIONINE SULFOXIDE REDUCTASE PEPTIDE METHIONINE SULFOXIDE REDUCTASE MSRA 2 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC121832846|UniProtKB=A0ACM8FY08 A0ACM8FY08 LOC121832846 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC8051955|UniProtKB=A0ACM8DLJ1 A0ACM8DLJ1 LOC8051955 PTHR12027:SF102 WNT RELATED PROTEIN WNT signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488 cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell differentiation#GO:0030154;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell fate commitment#GO:0045165;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 IXOSC|EnsemblGenome=LOC8033370|UniProtKB=A0ACM8FUS5 A0ACM8FUS5 LOC8033370 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8043331|UniProtKB=A0ACM8DV66 A0ACM8DV66 cutlet PTHR23389:SF3 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 CHROMOSOME TRANSMISSION FIDELITY PROTEIN 18 HOMOLOG DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120846101|UniProtKB=A0ACM8G165 A0ACM8G165 LOC120846101 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8035497|UniProtKB=A0ACM8FFC6 A0ACM8FFC6 LOC8035497 PTHR22930:SF312 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835731|UniProtKB=A0ACM8FUV5 A0ACM8FUV5 LOC121835731 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8036444|UniProtKB=A0ACM8DJW3 A0ACM8DJW3 LOC8036444 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8035304|UniProtKB=A0ACM8DWS1 A0ACM8DWS1 LOC8035304 PTHR11675:SF68 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 7 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120850543|UniProtKB=A0ACM8F907 A0ACM8F907 CPT2 PTHR22589:SF16 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE 2, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;lipid modification#GO:0030258 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8043349|UniProtKB=A0ACM8DQK9 A0ACM8DQK9 LOC8043349 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8029868|UniProtKB=A0ACM8F7M4 A0ACM8F7M4 LOC8029868 PTHR45702:SF2 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;primary metabolic process#GO:0044238;membrane protein ectodomain proteolysis#GO:0006509;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 IXOSC|EnsemblGenome=LOC8034615|UniProtKB=A0ACM8E7Y0 A0ACM8E7Y0 LOC8034615 PTHR10026:SF13 CYCLIN LD24704P kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 kinase activator#PC00138;kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC115319149|UniProtKB=A0ACM8DZ98 A0ACM8DZ98 Coq2 PTHR11048:SF42 PRENYLTRANSFERASES 4-HYDROXYBENZOATE POLYPRENYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;mitochondrial membrane#GO:0031966;cell periphery#GO:0071944;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8035423|UniProtKB=A0ACM8ECL3 A0ACM8ECL3 LOC8035423 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC121833247|UniProtKB=A0ACM8FK21 A0ACM8FK21 LOC121833247 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836507|UniProtKB=A0ACM8G086 A0ACM8G086 LOC121836507 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310465|UniProtKB=A0ACM8DPS8 A0ACM8DPS8 LOC115310465 PTHR11024:SF21 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER PROTEIN SEC13 HOMOLOG positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;organelle organization#GO:0006996;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular localization#GO:0051641;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;regulation of signal transduction#GO:0009966;membrane organization#GO:0061024;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;positive regulation of intracellular signal transduction#GO:1902533;transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;vesicle budding from membrane#GO:0006900;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;positive regulation of cell communication#GO:0010647;COPII-coated vesicle budding#GO:0090114;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;positive regulation of TOR signaling#GO:0032008;localization#GO:0051179 intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;coated membrane#GO:0048475;vesicle coat#GO:0030120;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;bounding membrane of organelle#GO:0098588;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;vesicle#GO:0031982;nuclear pore outer ring#GO:0031080;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090 transporter#PC00227 IXOSC|EnsemblGenome=LOC121838060|UniProtKB=A0ACM8G7G5 A0ACM8G7G5 LOC121838060 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120848879|UniProtKB=A0ACM8F7K1 A0ACM8F7K1 LOC120848879 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311683|UniProtKB=A0ACM8DR41 A0ACM8DR41 LOC115311683 PTHR46152:SF3 NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN NF-KAPPA-B INHIBITOR-INTERACTING RAS-LIKE PROTEIN protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 IXOSC|EnsemblGenome=LOC8052088|UniProtKB=A0ACM8EX69 A0ACM8EX69 LOC8052088 PTHR43568:SF1 P PROTEIN CITRATE TRANSPORTER-LIKE DOMAIN-CONTAINING PROTEIN-RELATED transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121834626|UniProtKB=A0ACM8FQ92 A0ACM8FQ92 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC121835368|UniProtKB=A0ACM8FSW4 A0ACM8FSW4 LOC121835368 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8052477|UniProtKB=A0ACM8EXG6 A0ACM8EXG6 LOC8052477 PTHR12175:SF7 AD039 HT014 THIOREDOXIN FAMILY TRP26 PITH DOMAIN-CONTAINING PROTEIN 1 regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;regulation of developmental process#GO:0050793;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;regulation of myeloid cell differentiation#GO:0045637;regulation of hemopoiesis#GO:1903706;regulation of cell development#GO:0060284;positive regulation of myeloid cell differentiation#GO:0045639;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of multicellular organismal process#GO:0051239;biological regulation#GO:0065007;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121833942|UniProtKB=A0ACM8FPM4 A0ACM8FPM4 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8052134|UniProtKB=A0ACM8DLY2 A0ACM8DLY2 LOC8052134 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121046430|UniProtKB=A0ACM8FE42 A0ACM8FE42 LOC121046430 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120849056|UniProtKB=A0ACM8FIG0 A0ACM8FIG0 PTHR31781:SF1 UNC80 PROTEIN UNC-80 HOMOLOG passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;regulation of system process#GO:0044057;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 membrane protein complex#GO:0098796;membrane#GO:0016020;neuron projection#GO:0043005;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;sodium channel complex#GO:0034706 IXOSC|EnsemblGenome=LOC8051288|UniProtKB=A0ACM8E1A2 A0ACM8E1A2 Hnf4 PTHR24083:SF104 NUCLEAR HORMONE RECEPTOR TRANSCRIPTION FACTOR HNF-4 HOMOLOG nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8027000|UniProtKB=A0ACM8EB10 A0ACM8EB10 PTHR10544:SF0 60S RIBOSOMAL PROTEIN L28 LARGE RIBOSOMAL SUBUNIT PROTEIN EL28 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120850478|UniProtKB=A0ACM8FA28 A0ACM8FA28 LOC120850478 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC115332175|UniProtKB=A0ACM8FTT4 A0ACM8FTT4 LOC115332175 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115311193|UniProtKB=A0ACM8F7H9 A0ACM8F7H9 LOC115311193 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121837882|UniProtKB=A0ACM8G5J7 A0ACM8G5J7 LOC121837882 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115331562|UniProtKB=A0ACM8F4X5 A0ACM8F4X5 LOC115331562 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120838248|UniProtKB=A0ACM8ENI0 A0ACM8ENI0 LOC120839980 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120849479|UniProtKB=A0ACM8F7Z6 A0ACM8F7Z6 LOC120849479 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115331172|UniProtKB=A0ACM8G7U7 A0ACM8G7U7 LOC115331172 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121046219|UniProtKB=A0ACM8FEI3 A0ACM8FEI3 LOC121046219 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;binding#GO:0005488;steroid hydroxylase activity#GO:0008395;tetrapyrrole binding#GO:0046906 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120840957|UniProtKB=A0ACM8FFW9 A0ACM8FFW9 LOC120840957 PTHR11733:SF245 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-1 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120836740|UniProtKB=A0ACM8EFA9 A0ACM8EFA9 LOC120836740 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8026216|UniProtKB=A0ACM8DZX1 A0ACM8DZX1 LOC8026216 PTHR13703:SF25 SMAD SMAD FAMILY MEMBER 2 nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;protein binding#GO:0005515;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cellular response to stimulus#GO:0051716;BMP signaling pathway#GO:0030509;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;developmental process#GO:0032502;response to BMP#GO:0071772;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;activin receptor signaling pathway#GO:0032924;cellular response to growth factor stimulus#GO:0071363;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;positive regulation of transcription by RNA polymerase II#GO:0045944 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 ALP23B signaling pathway#P06209>SMOX#P06224;TGF-beta signaling pathway#P00052>RSmads#P01292;BMP/activin signaling pathway-drosophila#P06211>R-Smad#P06245;Activin beta signaling pathway#P06210>SMOX#P06236;MYO signaling pathway#P06215>SMOX#P06314 IXOSC|EnsemblGenome=LOC120846872|UniProtKB=A0ACM8F4A8 A0ACM8F4A8 LOC120846872 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120838852|UniProtKB=A0ACM8ELR1 A0ACM8ELR1 LOC120838852 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120840894|UniProtKB=A0ACM8EQQ2 A0ACM8EQQ2 Orc5 PTHR12705:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 ORIGIN RECOGNITION COMPLEX SUBUNIT 5 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA replication origin binding#GO:0003688;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nuclear origin of replication recognition complex#GO:0005664;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 replication origin binding protein#PC00199 IXOSC|EnsemblGenome=LOC121836339|UniProtKB=A0ACM8FYG5 A0ACM8FYG5 LOC121836339 PTHR11360:SF93 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 7-LIKE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC120843593|UniProtKB=A0ACM8EXJ7 A0ACM8EXJ7 LOC121837977 PTHR33147:SF39 DEFENSIN-LIKE PROTEIN 1 DEFENSIN-LIKE PROTEIN 98 response to stress#GO:0006950;defense response#GO:0006952;response to stimulus#GO:0050896 antimicrobial response protein#PC00051 IXOSC|EnsemblGenome=LOC8037665|UniProtKB=A0ACM8DM94 A0ACM8DM94 LOC8037665 PTHR12668:SF58 TRANSMEMBRANE PROTEIN 14, 15 TRANSMEMBRANE PROTEIN 14 HOMOLOG intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8053440|UniProtKB=A0ACM8EGL3 A0ACM8EGL3 LOC8053440 PTHR11662:SF462 SOLUTE CARRIER FAMILY 17 FI19708P1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8037504|UniProtKB=A0ACM8FM32 A0ACM8FM32 LOC8037504 PTHR11699:SF190 ALDEHYDE DEHYDROGENASE-RELATED 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;small molecule catabolic process#GO:0044282;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;tetrahydrofolate metabolic process#GO:0046653 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC115320168|UniProtKB=A0ACM8ETJ8 A0ACM8ETJ8 LOC115320168 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121834581|UniProtKB=A0ACM8FP60 A0ACM8FP60 PTHR21725:SF1 E3 UBIQUITIN-PROTEIN LIGASE UBR4 E3 UBIQUITIN-PROTEIN LIGASE UBR4 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8040339|UniProtKB=A0ACM8DZ67 A0ACM8DZ67 LOC8040339 PTHR43464:SF105 METHYLTRANSFERASE UBIQUINONE BIOSYNTHESIS O-METHYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115315946|UniProtKB=A0ACM8EVD7 A0ACM8EVD7 LOC115315946 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8027587|UniProtKB=A0ACM8FDA1 A0ACM8FDA1 LOC8027587 PTHR10075:SF100 BASIGIN RELATED PROTEIN SAX-3 cell adhesion molecule#PC00069 Axon guidance mediated by Slit/Robo#P00008>Robo#P00348 IXOSC|EnsemblGenome=LOC121835307|UniProtKB=A0ACM8FT39 A0ACM8FT39 LOC121835307 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120843141|UniProtKB=A0ACM8EVD6 A0ACM8EVD6 LOC120843141 PTHR43782:SF5 ARGINASE ARGINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8053451|UniProtKB=A0ACM8DUZ6 A0ACM8DUZ6 PTHR13384:SF19 G PATCH DOMAIN-CONTAINING PROTEIN 1 G PATCH DOMAIN-CONTAINING PROTEIN 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121047825|UniProtKB=A0ACM8FFL7 A0ACM8FFL7 LOC121047825 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026310|UniProtKB=A0ACM8E5Z7 A0ACM8E5Z7 LOC8026310 PTHR22883:SF43 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE APP acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;protein targeting#GO:0006605;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120843829|UniProtKB=A0ACM8EY11 A0ACM8EY11 LOC120843829 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115320962|UniProtKB=A0ACM8E0Q9 A0ACM8E0Q9 PTHR43015:SF1 D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE D-RIBITOL-5-PHOSPHATE CYTIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220 IXOSC|EnsemblGenome=LOC121838550|UniProtKB=A0ACM8G940 A0ACM8G940 LOC121838550 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121048692|UniProtKB=A0ACM8FIR6 A0ACM8FIR6 LOC121048692 PTHR45255:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 DNAJ HOMOLOG SUBFAMILY C MEMBER 24 metal ion binding#GO:0046872;cation binding#GO:0043169;molecular function activator activity#GO:0140677;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;ATPase activator activity#GO:0001671;iron ion binding#GO:0005506;molecular function regulator activity#GO:0098772;ferrous iron binding#GO:0008198 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8027256|UniProtKB=A0ACM8ECI6 A0ACM8ECI6 LOC8027256 PTHR10887:SF5 DNA2/NAM7 HELICASE FAMILY RNA HELICASE AQUARIUS RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8033354|UniProtKB=A0ACM8EIC4 A0ACM8EIC4 LOC8033354 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8025177|UniProtKB=A0ACM8DJ29 A0ACM8DJ29 LOC8025177 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8025354|UniProtKB=A0ACM8FU97 A0ACM8FU97 LOC8025354 PTHR48423:SF6 INTERLEUKIN-27 RECEPTOR SUBUNIT ALPHA LEUKEMIA INHIBITORY FACTOR RECEPTOR IXOSC|EnsemblGenome=LOC8042214|UniProtKB=A0ACM8FCU8 A0ACM8FCU8 LOC8042214 PTHR10529:SF270 AP COMPLEX SUBUNIT MU AP-4 COMPLEX SUBUNIT MU-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 protein targeting#GO:0006605;cytosolic transport#GO:0016482;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;lysosomal transport#GO:0007041;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034 Golgi apparatus#GO:0005794;AP-type membrane coat adaptor complex#GO:0030119;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane coat#GO:0030117;coated membrane#GO:0048475;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8023865|UniProtKB=A0ACM8FMT0 A0ACM8FMT0 PTHR24036:SF5 SKELETOR-RELATED THROMBOMODULIN transmembrane signal receptor#PC00197 Blood coagulation#P00011>Thrombomodulin#P00457 IXOSC|EnsemblGenome=LOC115321285|UniProtKB=A0ACM8EZL4 A0ACM8EZL4 LOC120844942 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316673|UniProtKB=A0ACM8DW57 A0ACM8DW57 LOC115316673 PTHR46814:SF1 EGALITARIAN, ISOFORM B EGALITARIAN, ISOFORM B RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule localization#GO:0033036;localization#GO:0051179;RNA localization#GO:0006403 IXOSC|EnsemblGenome=LOC115327012|UniProtKB=A0ACM8E6I8 A0ACM8E6I8 LOC115327012 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121047146|UniProtKB=A0ACM8FFU3 A0ACM8FFU3 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032826|UniProtKB=A0ACM8DH05 A0ACM8DH05 PTHR12280:SF30 PANTOTHENATE KINASE PANTOTHENATE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 IXOSC|EnsemblGenome=LOC120841845|UniProtKB=A0ACM8ESN0 A0ACM8ESN0 LOC120841845 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8051998|UniProtKB=A0ACM8DZP2 A0ACM8DZP2 LOC8051998 PTHR11132:SF427 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E1 active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8039292|UniProtKB=A0ACM8EJQ1 A0ACM8EJQ1 LOC8039292 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115325131|UniProtKB=A0ACM8F0L4 A0ACM8F0L4 LOC115325131 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8023826|UniProtKB=A0ACM8EBY3 A0ACM8EBY3 bigmax PTHR15741:SF25 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR MAX-LIKE PROTEIN X transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8030755|UniProtKB=A0ACM8E752 A0ACM8E752 Ltn1 PTHR12389:SF0 ZINC FINGER PROTEIN 294 E3 UBIQUITIN-PROTEIN LIGASE LISTERIN aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ribosomal large subunit binding#GO:0043023;catalytic activity#GO:0003824;transferase activity#GO:0016740;ribosome binding#GO:0043022;ubiquitin-like protein ligase activity#GO:0061659;protein-containing complex binding#GO:0044877;ubiquitin-protein transferase activity#GO:0004842;ribonucleoprotein complex binding#GO:0043021;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488 gene expression#GO:0010467;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;translational elongation#GO:0006414;protein biosynthetic process#GO:0160307;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;rescue of stalled cytosolic ribosome#GO:0072344;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121838351|UniProtKB=A0ACM8G7R4 A0ACM8G7R4 LOC121838351 PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120842286|UniProtKB=A0ACM8G3U0 A0ACM8G3U0 LOC120842286 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120842433|UniProtKB=A0ACM8ETL3 A0ACM8ETL3 LOC120842433 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033186|UniProtKB=A0ACM8E7I7 A0ACM8E7I7 Srp68 PTHR12860:SF0 SIGNAL RECOGNITION PARTICLE 68 KDA PROTEIN SIGNAL RECOGNITION PARTICLE SUBUNIT SRP68 protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115320833|UniProtKB=A0ACM8FL24 A0ACM8FL24 LOC115320833 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115330264|UniProtKB=A0ACM8EKG3 A0ACM8EKG3 LOC115330264 PTHR24346:SF112 MAP/MICROTUBULE AFFINITY-REGULATING KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8023925|UniProtKB=A0ACM8DHS0 A0ACM8DHS0 Ufc1 PTHR12921:SF0 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 UBIQUITIN-FOLD MODIFIER-CONJUGATING ENZYME 1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919;reticulophagy#GO:0061709;response to stress#GO:0006950;autophagy#GO:0006914;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;catabolic process#GO:0009056;response to stimulus#GO:0050896;macroautophagy#GO:0016236 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115331699|UniProtKB=A0ACM8FCX9 A0ACM8FCX9 Npl4 PTHR12710:SF0 NUCLEAR PROTEIN LOCALIZATION 4 NUCLEAR PROTEIN LOCALIZATION PROTEIN 4 HOMOLOG response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632 membrane protein complex#GO:0098796;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC8037630|UniProtKB=A0ACM8E375 A0ACM8E375 LOC8037630 PTHR42807:SF1 GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL GLUTARYL-COA DEHYDROGENASE, MITOCHONDRIAL metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8030285|UniProtKB=A0ACM8DGK1 A0ACM8DGK1 RpII15 PTHR11239:SF1 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB9 catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;response to stimulus#GO:0050896;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;response to stress#GO:0006950;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 IXOSC|EnsemblGenome=LOC8053618|UniProtKB=A0ACM8E2G8 A0ACM8E2G8 LOC8053618 PTHR19321:SF57 PROTEIN REGULATOR OF CYTOKINESIS 1 PRC1-RELATED FASCETTO-RELATED protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 chromosome organization#GO:0051276;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;nuclear division#GO:0000280;organelle assembly#GO:0070925;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049 mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC115314040|UniProtKB=A0ACM8ES62 A0ACM8ES62 LOC115328436 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8051535|UniProtKB=A0ACM8EX16 A0ACM8EX16 LOC8051535 PTHR16840:SF3 GROWTH ARREST-SPECIFIC PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 1 biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120840511|UniProtKB=A0ACM8EQC5 A0ACM8EQC5 LOC120840511 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040948|UniProtKB=A0ACM8FDC2 A0ACM8FDC2 LOC8040948 PTHR15131:SF3 SMALL NUCLEAR RNA ACTIVATING COMPLEX, POLYPEPTIDE 1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 1 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565 nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;snRNA transcription#GO:0009301;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8039239|UniProtKB=A0ACM8E890 A0ACM8E890 LOC8039239 PTHR13163:SF2 SPINAL CORD EXPRESSION PROTEIN 4 TRANSMEMBRANE PROTEIN 35B cellular component organization or biogenesis#GO:0071840;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;protein-containing complex organization#GO:0043933;chaperone-mediated protein complex assembly#GO:0051131;cellular component assembly#GO:0022607;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC115324217|UniProtKB=A0ACM8E3Q9 A0ACM8E3Q9 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115329306|UniProtKB=A0ACM8E9C7 A0ACM8E9C7 Clbn PTHR15239:SF6 NUCLEAR EXPORT MEDIATOR FACTOR NEMF RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF ribosomal large subunit binding#GO:0043023;binding#GO:0005488;nucleic acid binding#GO:0003676;ribosome binding#GO:0043022;tRNA binding#GO:0000049;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;translational elongation#GO:0006414;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;modification-dependent macromolecule catabolic process#GO:0043632;translation#GO:0006412;protein catabolic process#GO:0030163;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;rescue of stalled cytosolic ribosome#GO:0072344;modification-dependent protein catabolic process#GO:0019941;protein biosynthetic process#GO:0160307;catabolic process#GO:0009056;cytoplasmic translation#GO:0002181 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115326071|UniProtKB=A0ACM8E6V4 A0ACM8E6V4 LOC115326071 PTHR24393:SF175 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120843917|UniProtKB=A0ACM8FQM0 A0ACM8FQM0 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120836244|UniProtKB=A0ACM8FLP8 A0ACM8FLP8 LOC120836244 PTHR10579:SF178 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-LIKE ion channel#PC00133 IXOSC|EnsemblGenome=LOC8051643|UniProtKB=A0ACM8FBT9 A0ACM8FBT9 PTHR24355:SF28 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE 2 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>GPRK#P00840 IXOSC|EnsemblGenome=LOC115316366|UniProtKB=A0ACM8FGL6 A0ACM8FGL6 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023803|UniProtKB=A0ACM8DY02 A0ACM8DY02 LOC8023803 PTHR13615:SF3 GLYCOSYLTRANSFERASE-LIKE 1 TRNA-QUEUOSINE ALPHA-MANNOSYLTRANSFERASE transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8036888|UniProtKB=A0ACM8F0A7 A0ACM8F0A7 LOC8036888 PTHR23060:SF3 TESTIS EXPRESSED GENE 14 INACTIVE SERINE_THREONINE-PROTEIN KINASE TEX14 negative regulation of mitotic sister chromatid separation#GO:2000816;extracellular structure organization#GO:0043062;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;gamete generation#GO:0007276;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;metaphase chromosome alignment#GO:0051310;negative regulation of cell cycle#GO:0045786;chromosome separation#GO:0051304;mitotic spindle assembly checkpoint signaling#GO:0007094;attachment of spindle microtubules to kinetochore#GO:0008608;regulation of cell cycle process#GO:0010564;chromosome localization#GO:0050000;cell cycle checkpoint signaling#GO:0000075;negative regulation of chromosome organization#GO:2001251;organelle localization#GO:0051640;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;localization#GO:0051179;organelle fission#GO:0048285;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic sister chromatid separation#GO:0051306;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic cell cycle#GO:0007346;mitotic sister chromatid segregation#GO:0000070;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;male gamete generation#GO:0048232;nuclear division#GO:0000280;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of chromosome segregation#GO:0051985;meiotic cell cycle#GO:0051321;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046;male meiotic nuclear division#GO:0007140;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;sexual reproduction#GO:0019953;multicellular organismal reproductive process#GO:0048609;regulation of mitotic sister chromatid segregation#GO:0033047;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of organelle organization#GO:0010639;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;chromosome organization#GO:0051276;meiotic nuclear division#GO:0140013;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;kinetochore#GO:0000776;condensed chromosome, centromeric region#GO:0000779;midbody#GO:0030496;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775 IXOSC|EnsemblGenome=LOC8034565|UniProtKB=A0ACM8E8X3 A0ACM8E8X3 LOC8034565 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8032685|UniProtKB=A0ACM8E5C4 A0ACM8E5C4 LOC8032685 PTHR24241:SF161 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120838748|UniProtKB=A0ACM8FQE5 A0ACM8FQE5 LOC120838748 PTHR42693:SF33 ARYLSULFATASE FAMILY MEMBER PUTATIVE (AFU_ORTHOLOGUE AFUA_5G12940)-RELATED hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115331693|UniProtKB=A0ACM8EVC7 A0ACM8EVC7 LOC115331693 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839646|UniProtKB=A0ACM8ENB0 A0ACM8ENB0 LOC120839646 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321791|UniProtKB=A0ACM8EV87 A0ACM8EV87 LOC115321791 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035804|UniProtKB=A0ACM8EFR2 A0ACM8EFR2 LOC8035804 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8035284|UniProtKB=A0ACM8DJR9 A0ACM8DJR9 LOC8035284 PTHR10562:SF151 SMALL UBIQUITIN-RELATED MODIFIER SMALL UBIQUITIN-RELATED MODIFIER 1 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 post-translational protein modification#GO:0043687;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein sumoylation#GO:0016925;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;PML body#GO:0016605;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 p53 pathway#P00059>Sumo-1 ligase#P04635 IXOSC|EnsemblGenome=LOC121833978|UniProtKB=A0ACM8FP09 A0ACM8FP09 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120840915|UniProtKB=A0ACM8EQ41 A0ACM8EQ41 LOC120840915 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8050574|UniProtKB=A0ACM8DLG1 A0ACM8DLG1 LOC8050574 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC-RELATED protein binding#GO:0005515;binding#GO:0005488 cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 IXOSC|EnsemblGenome=LOC115311732|UniProtKB=A0ACM8FVF9 A0ACM8FVF9 LOC115311732 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309159|UniProtKB=A0ACM8EKT5 A0ACM8EKT5 LOC115309159 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8034254|UniProtKB=A0ACM8EB59 A0ACM8EB59 PTHR21349:SF0 50S RIBOSOMAL PROTEIN L21 LARGE RIBOSOMAL SUBUNIT PROTEIN BL21M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 Methylcitrate cycle#P02754>Aconitase#P03028 IXOSC|EnsemblGenome=LOC120838989|UniProtKB=A0ACM8EL03 A0ACM8EL03 LOC120838989 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312265|UniProtKB=A0ACM8F399 A0ACM8F399 LOC115312265 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120840453|UniProtKB=A0ACM8EP35 A0ACM8EP35 LOC120840453 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027756|UniProtKB=A0ACM8F5P7 A0ACM8F5P7 LOC8027756 PTHR12308:SF51 ANOCTAMIN ANOCTAMIN-8 intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC115330797|UniProtKB=A0ACM8ECB4 A0ACM8ECB4 LOC115330797 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8053671|UniProtKB=A0ACM8DX48 A0ACM8DX48 LOC8053671 PTHR43243:SF17 INNER MEMBRANE TRANSPORTER YGJI-RELATED SOLUTE CARRIER FAMILY 7 MEMBER 14 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;establishment of localization#GO:0051234;amino acid transport#GO:0006865;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 amino acid transporter#PC00046;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8052304|UniProtKB=A0ACM8DY72 A0ACM8DY72 rdgB PTHR10658:SF81 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN PROTEIN RETINAL DEGENERATION B cation binding#GO:0043169;intramembrane lipid carrier activity#GO:0140303;anion binding#GO:0043168;small molecule binding#GO:0036094;lipid carrier activity#GO:0005319;phosphatidylcholine intramembrane carrier activity#GO:0008525;ion binding#GO:0043167;phosphatidylinositol transfer activity#GO:0008526;phosphatidylcholine binding#GO:0031210;phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;lipid binding#GO:0008289;lipid transfer activity#GO:0120013;binding#GO:0005488;molecular carrier activity#GO:0140104;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transporter#PC00227 IXOSC|EnsemblGenome=LOC115330198|UniProtKB=A0ACM8EBE2 A0ACM8EBE2 BCL7-like PTHR12767:SF9 BCL7 RELATED BCL7-LIKE cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8035780|UniProtKB=A0ACM8F6E5 A0ACM8F6E5 LOC8035780 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120846467|UniProtKB=A0ACM8FKV7 A0ACM8FKV7 LOC120846467 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845275|UniProtKB=A0ACM8FGP7 A0ACM8FGP7 LOC120845275 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115325681|UniProtKB=A0ACM8E607 A0ACM8E607 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120837513|UniProtKB=A0ACM8EIK8 A0ACM8EIK8 LOC120837513 PTHR10129:SF50 TRANSCRIPTION FACTOR MAF TRAFFIC JAM, ISOFORM C nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120842945|UniProtKB=A0ACM8EUY9 A0ACM8EUY9 LOC120842945 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8051085|UniProtKB=A0ACM8E5A0 A0ACM8E5A0 LOC8051085 PTHR19303:SF80 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115329813|UniProtKB=A0ACM8F7L4 A0ACM8F7L4 LOC115329813 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC8032836|UniProtKB=A0ACM8DH06 A0ACM8DH06 LOC8032836 PTHR12170:SF3 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED GH10162P catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8034352|UniProtKB=A0ACM8E2R8 A0ACM8E2R8 APP-BP1 PTHR10953:SF29 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 REGULATORY SUBUNIT catalytic activity, acting on a protein#GO:0140096;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity#GO:0016874;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657 post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8051742|UniProtKB=A0ACM8E920 A0ACM8E920 LOC8051742 PTHR23284:SF0 PROLACTIN REGULATORY ELEMENT BINDING PROTEIN GUANINE NUCLEOTIDE-EXCHANGE FACTOR SEC12 COPII-coated vesicle budding#GO:0090114;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;membrane organization#GO:0061024 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC115332910|UniProtKB=A0ACM8EES5 A0ACM8EES5 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053955|UniProtKB=A0ACM8E955 A0ACM8E955 LOC8053955 PTHR12489:SF19 LIPOMA HMGIC FUSION PARTNER-LIKE PROTEIN LHFPL TETRASPAN SUBFAMILY MEMBER 2 PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115329946|UniProtKB=A0ACM8EZD7 A0ACM8EZD7 LOC115329946 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8026893|UniProtKB=A0ACM8ESU4 A0ACM8ESU4 LOC8026893 PTHR22977:SF1 COX ASSEMBLY MITOCHONDRIAL PROTEIN COX ASSEMBLY MITOCHONDRIAL PROTEIN 2 HOMOLOG cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8041428|UniProtKB=A0ACM8E705 A0ACM8E705 LOC8041428 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120839369|UniProtKB=A0ACM8G1R1 A0ACM8G1R1 Nf-YB PTHR11064:SF9 CCAAT-BINDING TRANSCRIPTION FACTOR-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT BETA transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 IXOSC|EnsemblGenome=LOC120844021|UniProtKB=A0ACM8EXI5 A0ACM8EXI5 LOC120844021 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120850037|UniProtKB=A0ACM8F8W5 A0ACM8F8W5 LOC120850037 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838893|UniProtKB=A0ACM8ELU5 A0ACM8ELU5 LOC120838893 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121835694|UniProtKB=A0ACM8FW69 A0ACM8FW69 LOC121835694 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8051976|UniProtKB=A0ACM8FUT9 A0ACM8FUT9 LOC8051976 PTHR33215:SF13 PROTEIN DISTAL ANTENNA PROTEIN DISTAL ANTENNA IXOSC|EnsemblGenome=LOC8028740|UniProtKB=A0ACM8DH69 A0ACM8DH69 LOC8028740 PTHR13360:SF1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 ACTIVATING SIGNAL COINTEGRATOR 1 COMPLEX SUBUNIT 1 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8050929|UniProtKB=A0ACM8FB25 A0ACM8FB25 LOC8050929 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115318473|UniProtKB=A0ACM8DY41 A0ACM8DY41 LOC115318473 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030348|UniProtKB=A0ACM8FLN6 A0ACM8FLN6 LOC8030348 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8033746|UniProtKB=A0ACM8DI91 A0ACM8DI91 LOC8033746 PTHR43139:SF52 SI:DKEY-122A22.2 MESODERM-SPECIFIC TRANSCRIPT PROTEIN serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8025948|UniProtKB=A0ACM8G3B6 A0ACM8G3B6 LOC8025948 PTHR11559:SF370 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE-RELATED esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 IXOSC|EnsemblGenome=LOC8028779|UniProtKB=A0ACM8E5K4 A0ACM8E5K4 LOC8028779 PTHR46063:SF1 KELCH DOMAIN-CONTAINING PROTEIN KELCH DOMAIN-CONTAINING PROTEIN 4 IXOSC|EnsemblGenome=LOC120842764|UniProtKB=A0ACM8EUJ6 A0ACM8EUJ6 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837735|UniProtKB=A0ACM8G4X5 A0ACM8G4X5 LOC121837735 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8024992|UniProtKB=A0ACM8DIX3 A0ACM8DIX3 LOC8024992 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8043010|UniProtKB=A0ACM8DRT8 A0ACM8DRT8 LOC8043010 PTHR24359:SF1 SERINE/THREONINE-PROTEIN KINASE SBK1 INACTIVE PROTEIN KINASE DDB_G0270444-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121837331|UniProtKB=A0ACM8G4J2 A0ACM8G4J2 LOC121837331 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8053749|UniProtKB=A0ACM8EHR7 A0ACM8EHR7 LOC8053749 PTHR24243:SF238 G-PROTEIN COUPLED RECEPTOR THYROTROPIN-RELEASING HORMONE RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8052749|UniProtKB=A0ACM8ESU2 A0ACM8ESU2 LOC8052749 PTHR23199:SF13 NEUROTROPHIN 1-RELATED PROTEIN SPAETZLE 3 growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;central nervous system development#GO:0007417;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;anatomical structure formation involved in morphogenesis#GO:0048646;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;multicellular organism development#GO:0007275;developmental process#GO:0032502;nervous system development#GO:0007399;response to other organism#GO:0051707;defense response to other organism#GO:0098542;multicellular organismal process#GO:0032501;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8041191|UniProtKB=A0ACM8DVH0 A0ACM8DVH0 LOC8041191 PTHR16515:SF59 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 1 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8027247|UniProtKB=A0ACM8DUI4 A0ACM8DUI4 LOC8027247 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040126|UniProtKB=A0ACM8FYM3 A0ACM8FYM3 LOC8040126 PTHR10909:SF390 ELECTRON TRANSPORT OXIDOREDUCTASE PEROXISOMAL ACYL-COENZYME A OXIDASE 3 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;organic acid binding#GO:0043177;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;fatty acid binding#GO:0005504;lipid binding#GO:0008289;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleotide binding#GO:0000166 small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120843355|UniProtKB=A0ACM8EVW5 A0ACM8EVW5 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034425|UniProtKB=A0ACM8DUV7 A0ACM8DUV7 LOC8034425 PTHR16516:SF4 AGAP007109-PA PR DOMAIN ZINC FINGER PROTEIN 8-LIKE regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8042570|UniProtKB=A0ACM8DW89 A0ACM8DW89 Gpo1 PTHR11985:SF15 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121835532|UniProtKB=A0ACM8FUK9 A0ACM8FUK9 LOC121835532 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837848|UniProtKB=A0ACM8DMA9 A0ACM8DMA9 LOC8027507 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120842405|UniProtKB=A0ACM8ETR3 A0ACM8ETR3 LOC120842405 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121833279|UniProtKB=A0ACM8FK73 A0ACM8FK73 LOC121833279 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115328902|UniProtKB=A0ACM8EWY5 A0ACM8EWY5 LOC115328902 PTHR46560:SF5 CYPHER, ISOFORM B ZP DOMAIN-CONTAINING PROTEIN anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;cell morphogenesis#GO:0000902;anatomical structure development#GO:0048856 apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8029023|UniProtKB=A0ACM8E141 A0ACM8E141 Rpt2 PTHR23073:SF24 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 4 ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC120839862|UniProtKB=A0ACM8EMP5 A0ACM8EMP5 LOC120839862 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849101|UniProtKB=A0ACM8F7E2 A0ACM8F7E2 LOC120849101 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031424|UniProtKB=A0ACM8DMM8 A0ACM8DMM8 Snr1 PTHR10019:SF18 SNF5 SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY B MEMBER 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 IXOSC|EnsemblGenome=LOC115323387|UniProtKB=A0ACM8EQB6 A0ACM8EQB6 LOC115323387 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120843596|UniProtKB=A0ACM8EWJ8 A0ACM8EWJ8 LOC120843596 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8030125|UniProtKB=A0ACM8F4R3 A0ACM8F4R3 cactin PTHR21737:SF4 POLYGLUTAMINE BINDING PROTEIN 1/MARVEL MEMBRANE-ASSOCIATING DOMAIN CONTAINING 3 SPLICING FACTOR CACTIN RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;spliceosomal complex#GO:0005681;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115318412|UniProtKB=A0ACM8DXW3 A0ACM8DXW3 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031804|UniProtKB=A0ACM8DIS6 A0ACM8DIS6 PTHR47148:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 1 HOMOLOG mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8030960|UniProtKB=A0ACM8DTY6 A0ACM8DTY6 LOC8030960 PTHR21324:SF2 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED CWH43-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120836082|UniProtKB=A0ACM8ERA5 A0ACM8ERA5 LOC120836082 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8043950|UniProtKB=A0ACM8DYW3 A0ACM8DYW3 CAH1 PTHR18952:SF141 CARBONIC ANHYDRASE CARBONIC ANHYDRASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 IXOSC|EnsemblGenome=LOC8033225|UniProtKB=A0ACM8DHK0 A0ACM8DHK0 LOC8033225 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 metabolic process#GO:0008152;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC120850011|UniProtKB=A0ACM8F8U9 A0ACM8F8U9 LOC120850011 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035621|UniProtKB=A0ACM8DJV0 A0ACM8DJV0 LOC8035621 PTHR11071:SF582 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8040793|UniProtKB=A0ACM8E3T7 A0ACM8E3T7 LOC8040793 PTHR12231:SF279 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN ROUNDABOUT 1, ISOFORM A-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;cell recognition#GO:0008037;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902 cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;main axon#GO:0044304;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;leading edge membrane#GO:0031256;axon#GO:0030424;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115332183|UniProtKB=A0ACM8EDX6 A0ACM8EDX6 LOC115332183 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8034772|UniProtKB=A0ACM8ENX1 A0ACM8ENX1 LOC8034772 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115319330|UniProtKB=A0ACM8DZL2 A0ACM8DZL2 tam PTHR10267:SF0 DNA POLYMERASE SUBUNIT GAMMA-1 DNA POLYMERASE SUBUNIT GAMMA-1 exonuclease activity#GO:0004527;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;transferase activity#GO:0016740;DNA exonuclease activity#GO:0004529;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;hydrolase activity#GO:0016787;DNA-directed DNA polymerase activity#GO:0003887;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788 macromolecule metabolic process#GO:0043170;mitochondrial DNA metabolic process#GO:0032042;DNA-templated DNA replication#GO:0006261;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260 intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233 DNA-directed DNA polymerase#PC00018 IXOSC|EnsemblGenome=LOC8038899|UniProtKB=A0ACM8G3I8 A0ACM8G3I8 LOC8038899 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8051155|UniProtKB=A0ACM8DPD9 A0ACM8DPD9 PTHR12949:SF0 RNA POLYMERASE III DNA DIRECTED -RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC8043514|UniProtKB=A0ACM8G3V4 A0ACM8G3V4 LOC8043514 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291 sodium ion transport#GO:0006814;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8032220|UniProtKB=A0ACM8E3B7 A0ACM8E3B7 LOC8032220 PTHR11863:SF241 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;primary metabolic process#GO:0044238;cellular process#GO:0009987 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 oxidase#PC00175 IXOSC|EnsemblGenome=LOC120846885|UniProtKB=A0ACM8F388 A0ACM8F388 LOC120846885 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8040745|UniProtKB=A0ACM8E8N0 A0ACM8E8N0 LOC8040745 PTHR45746:SF5 LP21163P REGULATOR OF G-PROTEIN SIGNALING 7 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695 cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to oxygen-containing compound#GO:1901700;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025 IXOSC|EnsemblGenome=LOC8030970|UniProtKB=A0ACM8FX39 A0ACM8FX39 LOC8030970 PTHR12231:SF269 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN SUBFAMILY NOT NAMED binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8042213|UniProtKB=A0ACM8EGN1 A0ACM8EGN1 LOC8042213 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC115308177|UniProtKB=A0ACM8E0F9 A0ACM8E0F9 Phyhd1 PTHR20883:SF15 PHYTANOYL-COA DIOXYGENASE DOMAIN CONTAINING 1 PHYTANOYL-COA DIOXYGENASE DOMAIN-CONTAINING PROTEIN 1 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8040802|UniProtKB=A0ACM8DH53 A0ACM8DH53 LOC8040802 PTHR12298:SF8 PCDC2 PROGRAMMED CELL DEATH PROTEIN 2 -RELATED US5 ASSEMBLY CHAPERONE PDCD2 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC120846049|UniProtKB=A0ACM8F1B2 A0ACM8F1B2 LOC120846049 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040581|UniProtKB=A0ACM8DSL7 A0ACM8DSL7 Prp31 PTHR13904:SF0 PRE-MRNA SPLICING FACTOR PRP31 U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP31 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8035524|UniProtKB=A0ACM8FSU1 A0ACM8FSU1 mRpL10 PTHR11560:SF15 39S RIBOSOMAL PROTEIN L10, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL10M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8051588|UniProtKB=A0ACM8DM05 A0ACM8DM05 LOC8051588 PTHR46529:SF1 TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4 TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 4 methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 carbohydrate derivative metabolic process#GO:1901135;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8029945|UniProtKB=A0ACM8E0N9 A0ACM8E0N9 LOC8029945 PTHR21426:SF12 EXOCYST COMPLEX COMPONENT 8 EXOCYST COMPLEX COMPONENT 8 Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;localization within membrane#GO:0051668;Golgi vesicle transport#GO:0048193;transport#GO:0006810 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;exocyst#GO:0000145;cytoplasm#GO:0005737;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 IXOSC|EnsemblGenome=LOC121048281|UniProtKB=A0ACM8FGP5 A0ACM8FGP5 LOC121048281 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8039191|UniProtKB=A0ACM8FBN7 A0ACM8FBN7 LOC8039191 PTHR33236:SF13 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037611|UniProtKB=A0ACM8DI58 A0ACM8DI58 Bx42 PTHR12096:SF0 NUCLEAR PROTEIN SKIP-RELATED SNW DOMAIN-CONTAINING PROTEIN 1 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC121834259|UniProtKB=A0ACM8FPW4 A0ACM8FPW4 LOC121834259 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316321|UniProtKB=A0ACM8FY55 A0ACM8FY55 LOC115316321 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8050887|UniProtKB=A0ACM8DRI6 A0ACM8DRI6 LOC8050887 PTHR12877:SF15 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 17 guanyl-nucleotide exchange factor activity#GO:0005085;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC121837960|UniProtKB=A0ACM8G7A5 A0ACM8G7A5 LOC121837960 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8050708|UniProtKB=A0ACM8ENU3 A0ACM8ENU3 LOC8050708 PTHR31120:SF6 METALLOPROTEASE TIKI METALLOPROTEASE TIKI HOMOLOG protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115314979|UniProtKB=A0ACM8DU93 A0ACM8DU93 LOC115314979 PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 IXOSC|EnsemblGenome=LOC120839871|UniProtKB=A0ACM8EMA4 A0ACM8EMA4 LOC120839871 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC121837828|UniProtKB=A0ACM8G5B0 A0ACM8G5B0 LOC121837828 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837315|UniProtKB=A0ACM8EH39 A0ACM8EH39 LOC120837315 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332549|UniProtKB=A0ACM8EED0 A0ACM8EED0 LOC115332549 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8033045|UniProtKB=A0ACM8FQY6 A0ACM8FQY6 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8027343|UniProtKB=A0ACM8DPP0 A0ACM8DPP0 LOC8027343 PTHR24028:SF364 CADHERIN-87A CADHERIN 96CB, ISOFORM D cell adhesion#GO:0007155;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069;cadherin#PC00057 IXOSC|EnsemblGenome=LOC115312448|UniProtKB=A0ACM8DS42 A0ACM8DS42 LOC115312448 PTHR46708:SF2 TENASCIN FIBRONECTIN-LIKE extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8043368|UniProtKB=A0ACM8DTB0 A0ACM8DTB0 rhea PTHR19981:SF1 TALIN RHEA, ISOFORM B protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 Integrin signalling pathway#P00034>Talin#P00943 IXOSC|EnsemblGenome=LOC8041286|UniProtKB=A0ACM8ECH5 A0ACM8ECH5 LOC8041286 PTHR46259:SF1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 ZINC FINGER CCHC-TYPE AND RNA-BINDING MOTIF-CONTAINING PROTEIN 1 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8051531|UniProtKB=A0ACM8DLC4 A0ACM8DLC4 LOC8051531 PTHR11893:SF40 INNEXIN INNEXIN SHAKING-B transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;wide pore channel activity#GO:0022829 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 gap junction#PC00105 IXOSC|EnsemblGenome=LOC8041833|UniProtKB=A0ACM8EE26 A0ACM8EE26 LOC8041833 PTHR10794:SF98 ABHYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE 1, ISOFORM A hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115327481|UniProtKB=A0ACM8E721 A0ACM8E721 LOC115327481 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8033296|UniProtKB=A0ACM8FCG1 A0ACM8FCG1 PTHR18806:SF4 RBM25 PROTEIN RNA-BINDING PROTEIN 25 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381 IXOSC|EnsemblGenome=LOC8041416|UniProtKB=A0ACM8EB86 A0ACM8EB86 LOC8041416 PTHR16127:SF13 TAXILIN GH01188P membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8032968|UniProtKB=A0ACM8EKQ0 A0ACM8EKQ0 Dhod PTHR48109:SF4 DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL-RELATED DIHYDROOROTATE DEHYDROGENASE (QUINONE), MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;ribonucleotide metabolic process#GO:0009259;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;pyrimidine nucleobase metabolic process#GO:0006206;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Dihydrooratate oxidase#P02927 IXOSC|EnsemblGenome=LOC121046580|UniProtKB=A0ACM8FD39 A0ACM8FD39 LOC121046580 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115317724|UniProtKB=A0ACM8EP28 A0ACM8EP28 LOC115317724 PTHR23048:SF66 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN 2 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC120849952|UniProtKB=A0ACM8FZ15 A0ACM8FZ15 LOC120849952 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120839607|UniProtKB=A0ACM8EME1 A0ACM8EME1 LOC120839607 PTHR21166:SF2 CELL DIVISION CONTROL PROTEIN 24 OB DOMAIN-CONTAINING PROTEIN-RELATED MEIOSIS-SPECIFIC WITH OB DOMAIN-CONTAINING PROTEIN exonuclease activity#GO:0004527;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;3'-5'-DNA exonuclease activity#GO:0008296;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408 response to stimulus#GO:0050896;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;homologous recombination#GO:0035825;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;nucleobase-containing compound metabolic process#GO:0006139;resolution of meiotic recombination intermediates#GO:0000712;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8033943|UniProtKB=A0ACM8DIL1 A0ACM8DIL1 abo PTHR13374:SF3 DET1 HOMOLOG DE-ETIOLATED-1 HOMOLOG DET1 HOMOLOG enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;protein binding#GO:0005515;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;metabolic process#GO:0008152;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;protein ubiquitination#GO:0016567;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;protein modification by small protein conjugation or removal#GO:0070647;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121836326|UniProtKB=A0ACM8FZ81 A0ACM8FZ81 LOC121836326 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332258|UniProtKB=A0ACM8F5L2 A0ACM8F5L2 LOC115332258 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027390|UniProtKB=A0ACM8EQH1 A0ACM8EQH1 LOC8027390 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8039039|UniProtKB=A0ACM8DS53 A0ACM8DS53 KdelR PTHR10585:SF14 ER LUMEN PROTEIN RETAINING RECEPTOR ER LUMEN PROTEIN-RETAINING RECEPTOR signal sequence receptor activity#GO:0005048 cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365;cellular localization#GO:0051641 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cis-Golgi network#GO:0005801;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC120844157|UniProtKB=A0ACM8EY03 A0ACM8EY03 LOC120844157 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121835806|UniProtKB=A0ACM8FVX5 A0ACM8FVX5 LOC121835806 PTHR12308:SF84 ANOCTAMIN ANOCTAMIN molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;intramembrane lipid carrier activity#GO:0140303 transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC115313398|UniProtKB=A0ACM8FZL8 A0ACM8FZL8 Taf13 PTHR11380:SF17 TRANSCRIPTION INITIATION FACTOR TFIID/SUPT3-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 13 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8026098|UniProtKB=A0ACM8DWV5 A0ACM8DWV5 Cmtr1 PTHR16121:SF0 CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1-RELATED CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1 O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120848913|UniProtKB=A0ACM8F705 A0ACM8F705 LOC120848913 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121835197|UniProtKB=A0ACM8FSU3 A0ACM8FSU3 LOC121835197 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8044082|UniProtKB=A0ACM8G4T1 A0ACM8G4T1 Blos1 PTHR13073:SF0 BLOC-1 COMPLEX SUBUNIT 1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 1 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907 protein-containing complex#GO:0032991;BLOC-1 complex#GO:0031083;intracellular protein-containing complex#GO:0140535 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115309284|UniProtKB=A0ACM8EZ82 A0ACM8EZ82 LOC115309284 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115308945|UniProtKB=A0ACM8EZQ9 A0ACM8EZQ9 LOC115323178 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308685|UniProtKB=A0ACM8DMX0 A0ACM8DMX0 LOC115308685 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026543|UniProtKB=A0ACM8F7B1 A0ACM8F7B1 LOC8026543 PTHR10131:SF166 TNF RECEPTOR ASSOCIATED FACTOR RING FINGER PROTEIN 151 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 signal transduction#GO:0007165;regulation of canonical NF-kappaB signal transduction#GO:0043122;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115319999|UniProtKB=A0ACM8E0I6 A0ACM8E0I6 LOC115319999 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033381|UniProtKB=A0ACM8FR76 A0ACM8FR76 LOC8033381 PTHR13720:SF50 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;mitotic spindle#GO:0072686;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC120840808|UniProtKB=A0ACM8FID7 A0ACM8FID7 LOC121833143 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843735|UniProtKB=A0ACM8EXW4 A0ACM8EXW4 LOC120843735 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328130|UniProtKB=A0ACM8E7R1 A0ACM8E7R1 LOC115328130 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8038188|UniProtKB=A0ACM8DU37 A0ACM8DU37 ZnT63C PTHR45820:SF10 FI23527P1 ZINC TRANSPORTER 63C, ISOFORM F monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385 cellular process#GO:0009987;response to stress#GO:0006950;detoxification of inorganic compound#GO:0061687;monoatomic ion homeostasis#GO:0050801;detoxification#GO:0098754;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;response to chemical#GO:0042221;response to metal ion#GO:0010038;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115333060|UniProtKB=A0ACM8FJ21 A0ACM8FJ21 LOC115333060 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053178|UniProtKB=A0ACM8ED32 A0ACM8ED32 LOC8053178 PTHR11266:SF85 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 IXOSC|EnsemblGenome=LOC120848770|UniProtKB=A0ACM8FI39 A0ACM8FI39 LOC120848770 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115314892|UniProtKB=A0ACM8DU99 A0ACM8DU99 PTHR13312:SF0 HIV-INDUCED PROTEIN-7-LIKE PROTEASE UBIQUITIN THIOESTERASE OTU1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;catabolic process#GO:0009056;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC115324718|UniProtKB=A0ACM8E477 A0ACM8E477 LOC121836324 PTHR10231:SF106 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-GALACTOSE TRANSLOCATOR transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;UDP-galactose transmembrane transporter activity#GO:0005459;organophosphate ester transmembrane transporter activity#GO:0015605 transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;nucleotide-sugar transmembrane transport#GO:0015780;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 transporter#PC00227 IXOSC|EnsemblGenome=LOC120846141|UniProtKB=A0ACM8F1L4 A0ACM8F1L4 LOC120846141 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837594|UniProtKB=A0ACM8G457 A0ACM8G457 LOC121837594 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8042846|UniProtKB=A0ACM8FA80 A0ACM8FA80 LOC8042846 PTHR11690:SF296 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED DEGENERIN-LIKE PROTEIN DEL-10 sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8035151|UniProtKB=A0ACM8EUF5 A0ACM8EUF5 LOC8035151 PTHR43226:SF4 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO AMINOPEPTIDASE 3 catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115331683|UniProtKB=A0ACM8F9N8 A0ACM8F9N8 LOC115331683 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841723|UniProtKB=A0ACM8ES80 A0ACM8ES80 LOC120841723 PTHR11547:SF38 ARGININE OR CREATINE KINASE ARGININE KINASE 1-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121834838|UniProtKB=A0ACM8FQH8 A0ACM8FQH8 LOC121834838 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031944|UniProtKB=A0ACM8EES9 A0ACM8EES9 LOC8031944 PTHR10648:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC120837491|UniProtKB=A0ACM8EI89 A0ACM8EI89 LOC120837491 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115316823|UniProtKB=A0ACM8FBA0 A0ACM8FBA0 LOC115316823 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC8031133|UniProtKB=A0ACM8DHY1 A0ACM8DHY1 SNRPG PTHR10553:SF2 SMALL NUCLEAR RIBONUCLEOPROTEIN SMALL NUCLEAR RIBONUCLEOPROTEIN G RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;SMN-Sm protein complex#GO:0034719;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;U2 snRNP#GO:0005686;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;P granule#GO:0043186;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;precatalytic spliceosome#GO:0071011;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type prespliceosome#GO:0071004;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;U12-type spliceosomal complex#GO:0005689;nucleus#GO:0005634;U1 snRNP#GO:0005685;ribonucleoprotein granule#GO:0035770 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC115318434|UniProtKB=A0ACM8EMX3 A0ACM8EMX3 LOC115318434 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8034037|UniProtKB=A0ACM8DQB9 A0ACM8DQB9 LOC8034037 PTHR10344:SF9 THYMIDYLATE KINASE THYMIDYLATE KINASE phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside diphosphate metabolic process#GO:0009132;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transferase#PC00220;nucleotide kinase#PC00172;kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTMP kinase#P02916 IXOSC|EnsemblGenome=LOC8050709|UniProtKB=A0ACM8F6G6 A0ACM8F6G6 LOC8050709 PTHR14949:SF51 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 VON WILLEBRAND FACTOR D AND EGF DOMAIN-CONTAINING PROTEIN signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cellular anatomical structure#GO:0110165;cell surface#GO:0009986;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8050668|UniProtKB=A0ACM8DLR6 A0ACM8DLR6 Prosbeta2 PTHR11599:SF44 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 IXOSC|EnsemblGenome=LOC115325893|UniProtKB=A0ACM8F0X9 A0ACM8F0X9 LOC115325893 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026637|UniProtKB=A0ACM8E0V8 A0ACM8E0V8 PTHR48287:SF1 ARM REPEAT SUPERFAMILY PROTEIN RRNA PROCESSING PROTEIN RRP12-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8036375|UniProtKB=A0ACM8DJY6 A0ACM8DJY6 LOC8036375 PTHR34524:SF6 CALCYPHOSIN CALCYPHOSINE LIKE calcium-binding protein#PC00060;calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC120839900|UniProtKB=A0ACM8FD08 A0ACM8FD08 LOC120839900 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115316641|UniProtKB=A0ACM8EY63 A0ACM8EY63 LOC115316641 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120838773|UniProtKB=A0ACM8EJX2 A0ACM8EJX2 LOC120838773 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;enzyme regulator activity#GO:0030234;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of protein modification process#GO:0031399;negative regulation of cellular process#GO:0048523;regulation of protein ubiquitination#GO:0031396;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115314407|UniProtKB=A0ACM8DTN8 A0ACM8DTN8 LOC115314407 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050903|UniProtKB=A0ACM8DQ22 A0ACM8DQ22 PDCD-5 PTHR10840:SF0 PROGRAMMED CELL DEATH PROTEIN 5 PROGRAMMED CELL DEATH PROTEIN 5 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8028071|UniProtKB=A0ACM8DQU3 A0ACM8DQU3 LOC8028071 PTHR12459:SF27 TRANSMEMBRANE PROTEIN 135-RELATED TRANSMEMBRANE PROTEIN 135 IXOSC|EnsemblGenome=LOC8053654|UniProtKB=A0ACM8FL00 A0ACM8FL00 LOC8053654 PTHR11662:SF456 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER, ISOFORM A amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;L-amino acid transmembrane transporter activity#GO:0015179;acidic amino acid transmembrane transporter activity#GO:0015172;carboxylic acid transmembrane transporter activity#GO:0046943 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cellular localization#GO:0051641;regulation of synapse structure or activity#GO:0050803;localization#GO:0051179;cell communication#GO:0007154;regulation of biological quality#GO:0065008;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003 secretory vesicle#GO:0099503;membrane#GO:0016020;vesicle membrane#GO:0012506;presynapse#GO:0098793;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;cytoplasm#GO:0005737;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120839151|UniProtKB=A0ACM8ELK9 A0ACM8ELK9 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115308466|UniProtKB=A0ACM8DMJ0 A0ACM8DMJ0 LOC115308466 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120844738|UniProtKB=A0ACM8EZJ2 A0ACM8EZJ2 LOC120844738 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8036995|UniProtKB=A0ACM8FUA6 A0ACM8FUA6 LOC8036995 PTHR14918:SF4 KICSTOR COMPLEX PROTEIN SZT2 PROTEIN SZT2 negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of TOR signaling#GO:0032006;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579 IXOSC|EnsemblGenome=LOC121837174|UniProtKB=A0ACM8G3K7 A0ACM8G3K7 LOC121837174 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8040390|UniProtKB=A0ACM8FFT1 A0ACM8FFT1 LOC8040390 PTHR24406:SF26 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115329574|UniProtKB=A0ACM8FR06 A0ACM8FR06 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121834774|UniProtKB=A0ACM8FS02 A0ACM8FS02 LOC121834774 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120846869|UniProtKB=A0ACM8FG90 A0ACM8FG90 LOC120846869 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121834881|UniProtKB=A0ACM8FRK3 A0ACM8FRK3 LOC121834881 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120846505|UniProtKB=A0ACM8F2J5 A0ACM8F2J5 LOC120846505 PTHR14209:SF19 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;hydrolase#PC00121;esterase#PC00097 IXOSC|EnsemblGenome=LOC8053775|UniProtKB=A0ACM8F4U8 A0ACM8F4U8 LOC8053775 PTHR23164:SF30 EARLY ENDOSOME ANTIGEN 1 EARLY ENDOSOME ANTIGEN 1 lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 import into cell#GO:0098657;endocytosis#GO:0006897;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8044070|UniProtKB=A0ACM8FWD6 A0ACM8FWD6 LOC8044070 PTHR43475:SF1 METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE METHYLTHIORIBOSE-1-PHOSPHATE ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861 small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 isomerase#PC00135 IXOSC|EnsemblGenome=LOC120843754|UniProtKB=A0ACM8FVD6 A0ACM8FVD6 LOC120843754 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8053132|UniProtKB=A0ACM8EYB6 A0ACM8EYB6 LOC8053132 PTHR45629:SF15 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stimulus#GO:0050896;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 damaged DNA-binding protein#PC00086 IXOSC|EnsemblGenome=LOC120837346|UniProtKB=A0ACM8EH72 A0ACM8EH72 LOC120837346 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8035045|UniProtKB=A0ACM8EBL3 A0ACM8EBL3 LOC8035045 PTHR12947:SF22 AMSH-LIKE PROTEASE FI19924P1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity#GO:0003824;deubiquitinase activity#GO:0101005 transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;late endosome to vacuole transport#GO:0045324;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8039081|UniProtKB=A0ACM8F433 A0ACM8F433 LOC8039081 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 IXOSC|EnsemblGenome=LOC8040954|UniProtKB=A0ACM8FDI7 A0ACM8FDI7 LOC8040954 PTHR39075:SF1 FI19908P1 FI19908P1 IXOSC|EnsemblGenome=LOC120840410|UniProtKB=A0ACM8EP43 A0ACM8EP43 LOC120840410 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120844184|UniProtKB=A0ACM8EY26 A0ACM8EY26 LOC120844184 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031038|UniProtKB=A0ACM8EPF5 A0ACM8EPF5 LOC8031038 PTHR45630:SF7 CATION-TRANSPORTING ATPASE-RELATED FI03653P molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;protein carrier activity#GO:0140597 transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;transmembrane transport#GO:0055085;localization#GO:0051179;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120850233|UniProtKB=A0ACM8G0G8 A0ACM8G0G8 LOC120850233 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120848152|UniProtKB=A0ACM8F5B1 A0ACM8F5B1 LOC120848152 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025772|UniProtKB=A0ACM8G7T4 A0ACM8G7T4 LOC8025772 PTHR47194:SF3 SORTING NEXIN-29-RELATED SORTING NEXIN-29 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115332456|UniProtKB=A0ACM8EEK6 A0ACM8EEK6 LOC115332456 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC121837561|UniProtKB=A0ACM8G4Z2 A0ACM8G4Z2 LOC121837561 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120850091|UniProtKB=A0ACM8G3Q9 A0ACM8G3Q9 LOC120850091 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120844216|UniProtKB=A0ACM8EY88 A0ACM8EY88 LOC120844216 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024481|UniProtKB=A0ACM8EB99 A0ACM8EB99 LOC8024481 PTHR13193:SF0 CGI-140 PAT COMPLEX SUBUNIT ASTERIX cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120842780|UniProtKB=A0ACM8EUG0 A0ACM8EUG0 LOC120842780 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037227|UniProtKB=A0ACM8END7 A0ACM8END7 LOC8037227 PTHR31994:SF3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 42 IXOSC|EnsemblGenome=LOC8036271|UniProtKB=A0ACM8DWL8 A0ACM8DWL8 ScsbetaA PTHR11815:SF1 SUCCINYL-COA SYNTHETASE BETA CHAIN SUCCINATE--COA LIGASE [ADP-FORMING] SUBUNIT BETA, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;tricarboxylic acid cycle#GO:0006099;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;cellular respiration#GO:0045333;aerobic respiration#GO:0009060 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 ligase#PC00142 IXOSC|EnsemblGenome=LOC8035770|UniProtKB=A0ACM8ESD7 A0ACM8ESD7 LOC8035770 PTHR12887:SF11 NANOS PROTEIN PROTEIN NANOS mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;oogenesis#GO:0048477;negative regulation of translation#GO:0017148;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;reproductive process#GO:0022414;negative regulation of protein metabolic process#GO:0051248 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8039009|UniProtKB=A0ACM8DKA0 A0ACM8DKA0 LOC8039009 PTHR15895:SF13 IMMEDIATE EARLY RESPONSE GENE IMMEDIATE EARLY RESPONSE GENE 5-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120838164|UniProtKB=A0ACM8EIP2 A0ACM8EIP2 LOC120838164 PTHR22940:SF6 TIMEOUT/TIMELESS-2 PROTEIN TIMELESS binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;negative regulation of DNA-templated DNA replication#GO:2000104;response to external stimulus#GO:0009605;macromolecule metabolic process#GO:0043170;negative regulation of macromolecule metabolic process#GO:0010605;regulation of circadian rhythm#GO:0042752;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular response to stress#GO:0033554;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;DNA-templated DNA replication#GO:0006261;regulation of DNA replication#GO:0006275;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 IXOSC|EnsemblGenome=LOC120838076|UniProtKB=A0ACM8EJS1 A0ACM8EJS1 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;cellular process#GO:0009987;nervous system development#GO:0007399;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115314260|UniProtKB=A0ACM8FHX1 A0ACM8FHX1 LOC115314260 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053683|UniProtKB=A0ACM8DYS0 A0ACM8DYS0 PTHR11142:SF4 PSEUDOURIDYLATE SYNTHASE PSEUDOURIDYLATE SYNTHASE 1 HOMOLOG catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;isomerase activity#GO:0016853 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA modification#GO:0016556;pseudouridine synthesis#GO:0001522;tRNA modification#GO:0006400;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 lyase#PC00144 IXOSC|EnsemblGenome=LOC8029829|UniProtKB=A0ACM8DIY0 A0ACM8DIY0 Chrac-14 PTHR46172:SF1 DNA POLYMERASE EPSILON SUBUNIT 3 DNA POLYMERASE EPSILON SUBUNIT 3 nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;DNA binding#GO:0003677 DNA strand elongation involved in DNA replication#GO:0006271;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;epsilon DNA polymerase complex#GO:0008622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ISWI-type complex#GO:0031010;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120841479|UniProtKB=A0ACM8ERT7 A0ACM8ERT7 LOC120841479 PTHR12277:SF194 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN FI04476P hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 organophosphate catabolic process#GO:0046434;glycerolipid catabolic process#GO:0046503;phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;phosphorus metabolic process#GO:0006793;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;glycerophospholipid catabolic process#GO:0046475;lipid metabolic process#GO:0006629;neutral lipid catabolic process#GO:0046461;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;glycerophospholipid metabolic process#GO:0006650;cellular process#GO:0009987;lipid catabolic process#GO:0016042;organophosphate metabolic process#GO:0019637 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8053766|UniProtKB=A0ACM8DLS1 A0ACM8DLS1 SCCRO3 PTHR12281:SF31 RP42 RELATED DCN1-LIKE PROTEIN 3 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515 positive regulation of protein metabolic process#GO:0051247;regulation of protein modification process#GO:0031399;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8034486|UniProtKB=A0ACM8G014 A0ACM8G014 Cep97 PTHR45973:SF2 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED CENTROSOMAL PROTEIN OF 97 KDA regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;negative regulation of biological process#GO:0048519;regulation of cell projection assembly#GO:0060491;biological regulation#GO:0065007;regulation of organelle assembly#GO:1902115;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cilium assembly#GO:1902017;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC8025396|UniProtKB=A0ACM8ECK8 A0ACM8ECK8 Mvb12 PTHR31547:SF1 MULTIVESICULAR BODY SUBUNIT 12B MULTIVESICULAR BODY SUBUNIT 12B regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;regulation of cellular process#GO:0050794;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982 IXOSC|EnsemblGenome=LOC8034197|UniProtKB=A0ACM8EAE5 A0ACM8EAE5 Trs31 PTHR20902:SF0 41-2 PROTEIN ANTIGEN-RELATED TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 5 intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 IXOSC|EnsemblGenome=LOC120844602|UniProtKB=A0ACM8G906 A0ACM8G906 LOC120844602 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115308601|UniProtKB=A0ACM8FGP0 A0ACM8FGP0 LOC115308601 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837373|UniProtKB=A0ACM8G4P5 A0ACM8G4P5 LOC121837373 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC8033924|UniProtKB=A0ACM8EEC2 A0ACM8EEC2 LOC8033924 PTHR22604:SF105 OXIDOREDUCTASES TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120848348|UniProtKB=A0ACM8F5J6 A0ACM8F5J6 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115308293|UniProtKB=A0ACM8DM91 A0ACM8DM91 LOC115308293 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121835132|UniProtKB=A0ACM8FTK7 A0ACM8FTK7 LOC121835132 PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC8052793|UniProtKB=A0ACM8DT81 A0ACM8DT81 Myo31DF PTHR13140:SF713 MYOSIN UNCONVENTIONAL MYOSIN ID isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146 import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;transport#GO:0006810;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based movement#GO:0030048 intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell periphery#GO:0071944;membrane#GO:0016020 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC8036579|UniProtKB=A0ACM8E8U3 A0ACM8E8U3 PTHR11214:SF379 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8030904|UniProtKB=A0ACM8DM74 A0ACM8DM74 LOC8030904 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED IXOSC|EnsemblGenome=LOC8051190|UniProtKB=A0ACM8EEG8 A0ACM8EEG8 LOC8051190 PTHR43658:SF15 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 3-HYDROXYACYL-COA DEHYDROGENASE TYPE-2 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 steroid metabolic process#GO:0008202;biological regulation#GO:0065007;small molecule metabolic process#GO:0044281;hormone metabolic process#GO:0042445;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;regulation of biological quality#GO:0065008;estrogen metabolic process#GO:0008210;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052327|UniProtKB=A0ACM8FT24 A0ACM8FT24 alpha-PheRS PTHR11538:SF40 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE ALPHA SUBUNIT catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC121833248|UniProtKB=A0ACM8FKY9 A0ACM8FKY9 LOC121833248 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115314103|UniProtKB=A0ACM8ELS2 A0ACM8ELS2 LOC115314103 PTHR10165:SF35 LIPID PHOSPHATE PHOSPHATASE RE23632P catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phospholipid metabolic process#GO:0006644;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 cellular anatomical structure#GO:0110165;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115332861|UniProtKB=A0ACM8FCS6 A0ACM8FCS6 LOC115332861 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847767|UniProtKB=A0ACM8FRR5 A0ACM8FRR5 LOC120847767 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8033423|UniProtKB=A0ACM8DQS5 A0ACM8DQS5 LOC8033423 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8029033|UniProtKB=A0ACM8FHH5 A0ACM8FHH5 LOC8029033 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120843867|UniProtKB=A0ACM8EWS0 A0ACM8EWS0 LOC120843867 PTHR11003:SF346 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 18 voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8042067|UniProtKB=A0ACM8DKV8 A0ACM8DKV8 RfC3 PTHR11669:SF9 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 5 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity#GO:0140657;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;replication fork#GO:0005657;nucleus#GO:0005634;chromosome#GO:0005694 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 IXOSC|EnsemblGenome=LOC115323959|UniProtKB=A0ACM8EVE6 A0ACM8EVE6 LOC115323959 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC115309983|UniProtKB=A0ACM8DP63 A0ACM8DP63 LOC115309983 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115309111|UniProtKB=A0ACM8G8I9 A0ACM8G8I9 LOC115309111 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121836197|UniProtKB=A0ACM8FZ58 A0ACM8FZ58 LOC121836197 PTHR11003:SF356 POTASSIUM CHANNEL, SUBFAMILY K RE21922P voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC115311758|UniProtKB=A0ACM8EQ73 A0ACM8EQ73 LOC115311758 PTHR18947:SF39 HOOK PROTEINS PROTEIN HOOK binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular component organization#GO:0016043;cytoplasmic microtubule organization#GO:0031122;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;cytoskeleton organization#GO:0007010;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;microtubule-based process#GO:0007017 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8029218|UniProtKB=A0ACM8EPT0 A0ACM8EPT0 LOC8029218 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC8053809|UniProtKB=A0ACM8FDD9 A0ACM8FDD9 LOC8053809 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115331402|UniProtKB=A0ACM8FN36 A0ACM8FN36 PTHR12631:SF8 ALPHA-L-IDURONIDASE ALPHA-L-IDURONIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8035559|UniProtKB=A0ACM8DJU6 A0ACM8DJU6 LOC8035559 PTHR13952:SF6 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 35 KDA PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;snRNA binding#GO:0017069;RNA binding#GO:0003723 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120838147|UniProtKB=A0ACM8EJ51 A0ACM8EJ51 LOC120838147 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8038871|UniProtKB=A0ACM8EVE4 A0ACM8EVE4 LOC8038871 PTHR36694:SF14 PASIFLORA 1, ISOFORM A-RELATED LP21121P IXOSC|EnsemblGenome=LOC120838433|UniProtKB=A0ACM8EKT6 A0ACM8EKT6 LOC120838433 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121836734|UniProtKB=A0ACM8FZP9 A0ACM8FZP9 LOC121836734 PTHR11407:SF63 LYSOZYME C LYSOZYME hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;lysozyme activity#GO:0003796;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115333092|UniProtKB=A0ACM8F4X7 A0ACM8F4X7 LOC115333092 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120842170|UniProtKB=A0ACM8ET79 A0ACM8ET79 LOC120842170 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121837684|UniProtKB=A0ACM8G4P2 A0ACM8G4P2 LOC121837684 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120840187|UniProtKB=A0ACM8FX93 A0ACM8FX93 LOC120840187 PTHR12313:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8054081|UniProtKB=A0ACM8EB12 A0ACM8EB12 PAPLA1 PTHR23509:SF50 PA-PL1 PHOSPHOLIPASE FAMILY LD21067P phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134 metabolite interconversion enzyme#PC00262;phospholipase#PC00186 IXOSC|EnsemblGenome=LOC8052504|UniProtKB=A0ACM8DLI1 A0ACM8DLI1 LOC8052504 PTHR31159:SF1 COMM DOMAIN-CONTAINING PROTEIN 3 COMM DOMAIN-CONTAINING PROTEIN 3 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC120843306|UniProtKB=A0ACM8EVP1 A0ACM8EVP1 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042739|UniProtKB=A0ACM8FKP2 A0ACM8FKP2 LOC8042739 PTHR11616:SF340 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;glycine transmembrane transporter activity#GO:0015187;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215 amino acid transport#GO:0006865;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8032034|UniProtKB=A0ACM8FMV5 A0ACM8FMV5 LOC8032034 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE-LIKE transferase#PC00220 IXOSC|EnsemblGenome=LOC121833447|UniProtKB=A0ACM8FJT1 A0ACM8FJT1 LOC121833447 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845231|UniProtKB=A0ACM8F0D8 A0ACM8F0D8 LOC120845231 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837091|UniProtKB=A0ACM8G327 A0ACM8G327 LOC121837091 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318986|UniProtKB=A0ACM8DZG7 A0ACM8DZG7 LOC115318986 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838057|UniProtKB=A0ACM8EIZ1 A0ACM8EIZ1 LOC120838057 PTHR11715:SF3 GLYCINE CLEAVAGE SYSTEM H PROTEIN GLYCINE CLEAVAGE SYSTEM H PROTEIN-RELATED oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8026792|UniProtKB=A0ACM8DIB6 A0ACM8DIB6 dlt PTHR28678:SF1 CODANIN-1 CODANIN-1 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8024706|UniProtKB=A0ACM8F1F7 A0ACM8F1F7 LOC8024706 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317956|UniProtKB=A0ACM8DY58 A0ACM8DY58 LOC115317956 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311828|UniProtKB=A0ACM8EVN5 A0ACM8EVN5 LOC115311828 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115311704|UniProtKB=A0ACM8FU04 A0ACM8FU04 LOC115311704 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115321521|UniProtKB=A0ACM8F4M8 A0ACM8F4M8 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8053650|UniProtKB=A0ACM8E4E2 A0ACM8E4E2 LOC8053650 PTHR45755:SF1 FAMILY NOT NAMED PROTON-COUPLED ZINC ANTIPORTER SLC30A5 monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577 membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;Golgi cis cisterna#GO:0000137;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;Golgi stack#GO:0005795;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 IXOSC|EnsemblGenome=LOC120845910|UniProtKB=A0ACM8F1X8 A0ACM8F1X8 LOC120845910 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8041777|UniProtKB=A0ACM8EAW5 A0ACM8EAW5 LOC8041777 PTHR11224:SF10 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115319602|UniProtKB=A0ACM8FUH4 A0ACM8FUH4 LOC115319602 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;transferase complex#GO:1990234;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8023439|UniProtKB=A0ACM8EAF7 A0ACM8EAF7 ClC-c PTHR45711:SF12 CHLORIDE CHANNEL PROTEIN CHLORIDE CHANNEL PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;chloride transmembrane transporter activity#GO:0015108;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 inorganic anion transport#GO:0015698;system process#GO:0003008;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;renal system process#GO:0003014;monoatomic anion transport#GO:0006820 endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8030083|UniProtKB=A0ACM8EEB0 A0ACM8EEB0 LOC8030083 PTHR12622:SF4 DELTEX-RELATED PROTEIN DELTEX catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115331628|UniProtKB=A0ACM8FZW5 A0ACM8FZW5 LOC115331628 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC115324380|UniProtKB=A0ACM8F017 A0ACM8F017 LOC115324380 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835743|UniProtKB=A0ACM8FVL6 A0ACM8FVL6 LOC121835743 PTHR19446:SF487 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120848429|UniProtKB=A0ACM8FVJ5 A0ACM8FVJ5 LOC120848429 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC120844456|UniProtKB=A0ACM8EYQ1 A0ACM8EYQ1 LOC120844456 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8027777|UniProtKB=A0ACM8DNI5 A0ACM8DNI5 LOC8027777 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115324635|UniProtKB=A0ACM8G643 A0ACM8G643 LOC115324635 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8053835|UniProtKB=A0ACM8DWG4 A0ACM8DWG4 LOC8053835 PTHR11009:SF32 DER1-LIKE PROTEIN, DERLIN DERLIN cellular process#GO:0009987;signal transduction#GO:0007165;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to topologically incorrect protein#GO:0035967;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;response to unfolded protein#GO:0006986 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121836549|UniProtKB=A0ACM8FZ59 A0ACM8FZ59 LOC121836549 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8051114|UniProtKB=A0ACM8FSR2 A0ACM8FSR2 LOC8051114 PTHR13891:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 7 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036 cellular component assembly#GO:0022607;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cytochrome complex assembly#GO:0017004 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115329596|UniProtKB=A0ACM8E9U6 A0ACM8E9U6 EMC6 PTHR20994:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 6 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;organelle assembly#GO:0070925;catabolic process#GO:0009056;protein localization to organelle#GO:0033365;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;metabolic process#GO:0008152;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;macroautophagy#GO:0016236;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;cellular component assembly#GO:0022607;establishment of protein localization#GO:0045184;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036 membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;EMC complex#GO:0072546;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120846719|UniProtKB=A0ACM8F326 A0ACM8F326 LOC120846719 PTHR45080:SF45 CONTACTIN 5 IP11255P molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell junction organization#GO:0034330;cellular process#GO:0009987;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;synapse organization#GO:0050808 cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;axon#GO:0030424 IXOSC|EnsemblGenome=LOC8023312|UniProtKB=A0ACM8G578 A0ACM8G578 LOC8023312 PTHR10165:SF35 LIPID PHOSPHATE PHOSPHATASE RE23632P phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311 membrane#GO:0016020;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121838467|UniProtKB=A0ACM8G8Z2 A0ACM8G8Z2 LOC121838467 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845354|UniProtKB=A0ACM8F0K5 A0ACM8F0K5 LOC120845354 PTHR23301:SF108 CHITIN BINDING PERITROPHIN-A CHONDROITIN PROTEOGLYCAN-2-RELATED binding#GO:0005488;carbohydrate derivative binding#GO:0097367 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC115324447|UniProtKB=A0ACM8EIZ0 A0ACM8EIZ0 LOC115324447 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115327183|UniProtKB=A0ACM8F1G2 A0ACM8F1G2 LOC115327183 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318078|UniProtKB=A0ACM8DYD6 A0ACM8DYD6 LOC115318078 PTHR24023:SF1129 COLLAGEN ALPHA MULTIPLEXIN, ISOFORM R structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8029821|UniProtKB=A0ACM8FCS4 A0ACM8FCS4 LOC8029821 PTHR11530:SF11 D-AMINO ACID OXIDASE D-AMINO ACID OXIDASE 2, ISOFORM A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 IXOSC|EnsemblGenome=LOC120843891|UniProtKB=A0ACM8FNJ0 A0ACM8FNJ0 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832988|UniProtKB=A0ACM8FW79 A0ACM8FW79 LOC121832988 PTHR47667:SF2 REGULATOR OF TY1 TRANSPOSITION PROTEIN 107 BRCT DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8036765|UniProtKB=A0ACM8G6C9 A0ACM8G6C9 BBS1 PTHR20870:SF0 BARDET-BIEDL SYNDROME 1 PROTEIN BBSOME COMPLEX MEMBER BBS1 G protein-coupled receptor binding#GO:0001664;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;organelle assembly#GO:0070925;cilium organization#GO:0044782;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cell projection assembly#GO:0030031;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;BBSome#GO:0034464;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856 IXOSC|EnsemblGenome=LOC115318640|UniProtKB=A0ACM8DYB4 A0ACM8DYB4 LOC115318640 PTHR46421:SF1 PROGRAMMED CELL DEATH PROTEIN 2-LIKE US5 ASSEMBLY CHAPERONE PDCD2L programmed cell death#GO:0012501;cell death#GO:0008219;cellular process#GO:0009987;apoptotic process#GO:0006915 IXOSC|EnsemblGenome=LOC8032487|UniProtKB=A0ACM8FR41 A0ACM8FR41 LOC8032487 PTHR12595:SF0 POS9-ACTIVATING FACTOR FAP7-RELATED ADENYLATE KINASE ISOENZYME 6 phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside phosphate binding#GO:1901265;nucleobase-containing compound kinase activity#GO:0019205;ATP binding#GO:0005524;binding#GO:0005488;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8041539|UniProtKB=A0ACM8FJ36 A0ACM8FJ36 LOC8041539 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8051348|UniProtKB=A0ACM8E9I3 A0ACM8E9I3 LOC8051348 PTHR11125:SF7 SUPPRESSOR OF TY 5 TRANSCRIPTION ELONGATION FACTOR SPT5 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981 IXOSC|EnsemblGenome=LOC121836209|UniProtKB=A0ACM8FZ88 A0ACM8FZ88 LOC121836209 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120846575|UniProtKB=A0ACM8F2R7 A0ACM8F2R7 LOC120846575 PTHR46102:SF2 AXIN AXIN ubiquitin-like protein ligase binding#GO:0044389;ubiquitin protein ligase binding#GO:0031625;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;beta-catenin binding#GO:0008013 regulation of ubiquitin-dependent protein catabolic process#GO:2000058;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein metabolic process#GO:0051246;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;negative regulation of signal transduction#GO:0009968;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;cell development#GO:0048468;regulation of Wnt signaling pathway#GO:0030111;cell differentiation#GO:0030154;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;anatomical structure development#GO:0048856;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 IXOSC|EnsemblGenome=LOC8036426|UniProtKB=A0ACM8FT08 A0ACM8FT08 LOC8036426 PTHR11824:SF5 VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT CA2+-CHANNEL-PROTEIN-BETA-SUBUNIT, ISOFORM L voltage-gated ion channel#PC00241 Thyrotropin-releasing hormone receptor signaling pathway#P04394>Ca2+ channel#P04587 IXOSC|EnsemblGenome=LOC8039354|UniProtKB=A0ACM8DS58 A0ACM8DS58 Arf79F PTHR11711:SF479 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 1 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;guanyl nucleotide binding#GO:0019001 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cell periphery#GO:0071944 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 IXOSC|EnsemblGenome=LOC121045688|UniProtKB=A0ACM8FC38 A0ACM8FC38 LOC121045688 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8025605|UniProtKB=A0ACM8DSQ7 A0ACM8DSQ7 LOC8025605 PTHR24123:SF148 ANKYRIN REPEAT-CONTAINING IPT_TIG ANKYRIN REPEAT PROTEIN enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120840505|UniProtKB=A0ACM8EQC1 A0ACM8EQC1 LOC120840505 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040490|UniProtKB=A0ACM8DKL7 A0ACM8DKL7 Cdc37 PTHR12800:SF4 CDC37-RELATED HSP90 CO-CHAPERONE CDC37 binding#GO:0005488;heat shock protein binding#GO:0031072;protein binding#GO:0005515 primary metabolic process#GO:0044238;regulation of protein stability#GO:0031647;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821 protein folding chaperone complex#GO:0101031;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121837761|UniProtKB=A0ACM8G6B9 A0ACM8G6B9 LOC121837761 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041138|UniProtKB=A0ACM8DRQ5 A0ACM8DRQ5 LOC8041138 PTHR10057:SF23 PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR TRANSLOCATOR PROTEIN organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120846550|UniProtKB=A0ACM8F2D4 A0ACM8F2D4 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121048468|UniProtKB=A0ACM8FI86 A0ACM8FI86 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053609|UniProtKB=A0ACM8DM37 A0ACM8DM37 Noc3 PTHR14428:SF5 NUCLEOLAR COMPLEX PROTEIN 3 NUCLEOLAR COMPLEX PROTEIN 3 HOMOLOG binding#GO:0005488;chromatin binding#GO:0003682 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8041674|UniProtKB=A0ACM8DWM1 A0ACM8DWM1 LOC8041674 PTHR10615:SF222 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT7 histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;transcription regulator activity#GO:0140110;binding#GO:0005488;acetyltransferase activity#GO:0016407;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;histone acetyltransferase activity#GO:0004402;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 Alzheimer disease-presenilin pathway#P00004>Tip60#P00137 IXOSC|EnsemblGenome=LOC115311417|UniProtKB=A0ACM8DQR4 A0ACM8DQR4 LOC115311417 PTHR15430:SF1 GLOMULIN RE73310P enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of proteasomal protein catabolic process#GO:0061136;regulation of macromolecule metabolic process#GO:0060255;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein catabolic process#GO:0042176;regulation of catabolic process#GO:0009894;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8042901|UniProtKB=A0ACM8DL06 A0ACM8DL06 RpII33 PTHR11800:SF2 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB3 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on RNA#GO:0140098 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019 Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388;General transcription regulation#P00023>RNA Polymerase II#P00660 IXOSC|EnsemblGenome=LOC8039263|UniProtKB=A0ACM8EG88 A0ACM8EG88 LOC8039263 PTHR10404:SF84 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG carboxypeptidase activity#GO:0004180;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8042624|UniProtKB=A0ACM8G464 A0ACM8G464 Coq6 PTHR43876:SF7 UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS MONOOXYGENASE COQ6, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ubiquinone biosynthetic process#GO:0006744;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8031209|UniProtKB=A0ACM8E0N5 A0ACM8E0N5 LOC8031209 PTHR20872:SF1 FAMILY NOT NAMED F-BOX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312713|UniProtKB=A0ACM8FN58 A0ACM8FN58 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029928|UniProtKB=A0ACM8DJ39 A0ACM8DJ39 LOC8029928 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115317274|UniProtKB=A0ACM8DXE5 A0ACM8DXE5 LOC115317274 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120844195|UniProtKB=A0ACM8EXR7 A0ACM8EXR7 LOC120844195 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC120846651|UniProtKB=A0ACM8F2N4 A0ACM8F2N4 LOC120846651 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC115315834|UniProtKB=A0ACM8DVW8 A0ACM8DVW8 LOC115315834 PTHR45694:SF30 GLUTAREDOXIN 2 GLUTAREDOXIN-2, MITOCHONDRIAL oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115327422|UniProtKB=A0ACM8FI70 A0ACM8FI70 LOC115327422 PTHR47160:SF13 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834296|UniProtKB=A0ACM8FQ31 A0ACM8FQ31 PTHR48575:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036412|UniProtKB=A0ACM8E3P3 A0ACM8E3P3 Sbp2 PTHR13284:SF4 GH01354P RIBOSOMAL PROTEIN EL8_EL30_ES12_GADD45 DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;protein-containing complex binding#GO:0044877;mRNA 3'-UTR binding#GO:0003730;ribonucleoprotein complex binding#GO:0043021;RNA binding#GO:0003723 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC121836552|UniProtKB=A0ACM8G022 A0ACM8G022 LOC121836552 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322086|UniProtKB=A0ACM8E1N6 A0ACM8E1N6 LOC115322086 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836772|UniProtKB=A0ACM8G1E8 A0ACM8G1E8 LOC121836772 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324723|UniProtKB=A0ACM8E548 A0ACM8E548 LOC115324723 PTHR47163:SF5 DDE_TNP_IS1595 DOMAIN-CONTAINING PROTEIN ISXO2-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311305|UniProtKB=A0ACM8DQK6 A0ACM8DQK6 LOC115311305 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120844236|UniProtKB=A0ACM8EXV4 A0ACM8EXV4 LOC120844236 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309450|UniProtKB=A0ACM8DNU1 A0ACM8DNU1 LOC115309450 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC120844312|UniProtKB=A0ACM8EYC9 A0ACM8EYC9 LOC120844312 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051333|UniProtKB=A0ACM8DLW6 A0ACM8DLW6 LOC8051333 PTHR12532:SF12 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 TRANSLATIONAL ACTIVATOR OF CYTOCHROME C OXIDASE 1 positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of translation#GO:0045727;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121834783|UniProtKB=A0ACM8FR29 A0ACM8FR29 LOC121834783 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8044035|UniProtKB=A0ACM8ECU4 A0ACM8ECU4 LOC8044035 PTHR21191:SF16 AQUAPORIN AQUAPORIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 intracellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;regulation of cell size#GO:0008361;cellular homeostasis#GO:0019725;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;regulation of anatomical structure size#GO:0090066;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of cellular component size#GO:0032535;cellular process#GO:0009987;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC115324589|UniProtKB=A0ACM8G2H4 A0ACM8G2H4 LOC115324589 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8036605|UniProtKB=A0ACM8DK00 A0ACM8DK00 RagA-B PTHR11259:SF1 RAS-RELATED GTP BINDING RAG/GTR YEAST RAS-RELATED GTP-BINDING PROTEIN anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 negative regulation of catabolic process#GO:0009895;positive regulation of TOR signaling#GO:0032008;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;negative regulation of autophagy#GO:0010507;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;positive regulation of TORC1 signaling#GO:1904263;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;lysosome#GO:0005764;nucleus#GO:0005634 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC115319689|UniProtKB=A0ACM8E063 A0ACM8E063 LOC115319689 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8042461|UniProtKB=A0ACM8DZ21 A0ACM8DZ21 LOC8042461 PTHR23003:SF53 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE-ARGININE PROTEIN 55-LIKE PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120843250|UniProtKB=A0ACM8EVQ0 A0ACM8EVQ0 LOC120843250 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120844695|UniProtKB=A0ACM8F0F6 A0ACM8F0F6 LOC120844695 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846904|UniProtKB=A0ACM8FMV7 A0ACM8FMV7 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120849508|UniProtKB=A0ACM8F6Z7 A0ACM8F6Z7 LOC120849508 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8026114|UniProtKB=A0ACM8FV87 A0ACM8FV87 LOC8026114 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120843681|UniProtKB=A0ACM8EWP1 A0ACM8EWP1 LOC120843681 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC121834817|UniProtKB=A0ACM8FRA9 A0ACM8FRA9 LOC121834817 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325824|UniProtKB=A0ACM8E5W5 A0ACM8E5W5 LOC115325824 PTHR13285:SF26 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE RASP acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8033231|UniProtKB=A0ACM8E484 A0ACM8E484 LOC8033231 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC121835767|UniProtKB=A0ACM8FV17 A0ACM8FV17 LOC121835767 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033527|UniProtKB=A0ACM8E718 A0ACM8E718 Nup205 PTHR31344:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP205 NUCLEAR PORE COMPLEX PROTEIN NUP205 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 nuclear pore organization#GO:0006999;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8041673|UniProtKB=A0ACM8DRK2 A0ACM8DRK2 LOC8041673 PTHR19288:SF46 4-NITROPHENYLPHOSPHATASE-RELATED HALOACID DEHALOGENASE-LIKE HYDROLASE DOMAIN-CONTAINING PROTEIN 2 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC120847838|UniProtKB=A0ACM8F3Z2 A0ACM8F3Z2 LOC120847838 PTHR22904:SF532 TPR REPEAT CONTAINING PROTEIN HSP70_HSP90 ORGANIZING-LIKE PROTEIN heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;binding#GO:0005488;protein binding#GO:0005515 IXOSC|EnsemblGenome=LOC8041866|UniProtKB=A0ACM8DKT5 A0ACM8DKT5 LOC8041866 PTHR10061:SF0 S-FORMYLGLUTATHIONE HYDROLASE S-FORMYLGLUTATHIONE HYDROLASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120837615|UniProtKB=A0ACM8EHC8 A0ACM8EHC8 LOC120837615 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120843517|UniProtKB=A0ACM8EXD9 A0ACM8EXD9 LOC120843517 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC121837877|UniProtKB=A0ACM8G565 A0ACM8G565 LOC121837877 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833524|UniProtKB=A0ACM8FL80 A0ACM8FL80 LOC121833524 PTHR10574:SF446 NETRIN/LAMININ-RELATED WING BLISTER, ISOFORM B structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 IXOSC|EnsemblGenome=LOC115311250|UniProtKB=A0ACM8DQK4 A0ACM8DQK4 LOC115311250 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034976|UniProtKB=A0ACM8DJP7 A0ACM8DJP7 LOC8034976 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC120841945|UniProtKB=A0ACM8EST7 A0ACM8EST7 LOC120841945 PTHR47958:SF104 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE WM6 ATP-dependent activity#GO:0140657;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386 RNA biosynthetic process#GO:0032774;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;mRNA export from nucleus#GO:0006406;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC121836104|UniProtKB=A0ACM8FXC5 A0ACM8FXC5 LOC121836104 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115331140|UniProtKB=A0ACM8F3Z9 A0ACM8F3Z9 LOC115331140 PTHR43807:SF23 FI04487P FI04487P catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;transaminase#PC00216;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8042698|UniProtKB=A0ACM8FBX0 A0ACM8FBX0 Itpr PTHR45816:SF4 MIR DOMAIN-CONTAINING PROTEIN INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR IXOSC|EnsemblGenome=LOC8034260|UniProtKB=A0ACM8EJV5 A0ACM8EJV5 LOC8034260 PTHR12855:SF10 DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 FAMILY MEMBER DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1 transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;H4 histone acetyltransferase complex#GO:1902562;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;ATPase complex#GO:1904949;intracellular organelle lumen#GO:0070013;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115325876|UniProtKB=A0ACM8FA22 A0ACM8FA22 LOC115325876 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8035991|UniProtKB=A0ACM8FMP0 A0ACM8FMP0 PTHR22618:SF2 PROTEIN O-MANNOSE KINASE PROTEIN O-MANNOSE KINASE carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115311663|UniProtKB=A0ACM8DR19 A0ACM8DR19 LOC115311663 PTHR45931:SF3 SI:CH211-59O9.10 RING ZINC FINGER-CONTAINING PROTEIN ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8038462|UniProtKB=A0ACM8FE70 A0ACM8FE70 PTHR23122:SF42 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK MENAGE A TROIS, ISOFORM A cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8043049|UniProtKB=A0ACM8FG68 A0ACM8FG68 LOC8043049 PTHR12675:SF12 MUSCLEBLIND-LIKE PROTEIN PROTEIN MUSCLEBLIND nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120841629|UniProtKB=A0ACM8ERZ5 A0ACM8ERZ5 LOC120841629 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120840621|UniProtKB=A0ACM8EPN3 A0ACM8EPN3 LOC120840621 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC121046635|UniProtKB=A0ACM8FEI1 A0ACM8FEI1 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121837598|UniProtKB=A0ACM8G460 A0ACM8G460 LOC121837598 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839597|UniProtKB=A0ACM8EMQ6 A0ACM8EMQ6 LOC120839597 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046234|UniProtKB=A0ACM8FNZ0 A0ACM8FNZ0 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321259|UniProtKB=A0ACM8E242 A0ACM8E242 LOC115321259 PTHR13906:SF4 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 6 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 lipid modification#GO:0030258;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC8051341|UniProtKB=A0ACM8FGV6 A0ACM8FGV6 LOC8051341 PTHR24221:SF402 ATP-BINDING CASSETTE SUB-FAMILY B IRON-SULFUR CLUSTERS TRANSPORTER ABCB7, MITOCHONDRIAL active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;intracellular iron ion homeostasis#GO:0006879;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;transport#GO:0006810;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120849447|UniProtKB=A0ACM8F8R8 A0ACM8F8R8 LOC120849447 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115324856|UniProtKB=A0ACM8ELS1 A0ACM8ELS1 LOC115324856 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318361|UniProtKB=A0ACM8DYD1 A0ACM8DYD1 JMJD4 PTHR12480:SF6 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE JMJD4 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;sequence-specific DNA binding#GO:0043565;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of protein-containing complex disassembly#GO:0043244;regulation of translation#GO:0006417;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of protein metabolic process#GO:0051247;positive regulation of cellular component organization#GO:0051130;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of translation#GO:0045727;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8035106|UniProtKB=A0ACM8E8N8 A0ACM8E8N8 Shark PTHR24418:SF372 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 IXOSC|EnsemblGenome=LOC8036292|UniProtKB=A0ACM8DHC0 A0ACM8DHC0 LOC8036292 PTHR12289:SF41 METAXIN RELATED METAXIN-1 HOMOLOG cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003;protein localization to organelle#GO:0033365;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737 transporter#PC00227 IXOSC|EnsemblGenome=LOC8032063|UniProtKB=A0ACM8EGL9 A0ACM8EGL9 LOC8032063 PTHR14894:SF0 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 3 enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cell cycle#GO:0051726;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;signal transduction#GO:0007165;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC120836476|UniProtKB=A0ACM8EF40 A0ACM8EF40 LOC120836476 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC121834651|UniProtKB=A0ACM8FQK6 A0ACM8FQK6 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;protein modification by small protein conjugation or removal#GO:0070647;regulation of RNA metabolic process#GO:0051252;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;protein sumoylation#GO:0016925;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 IXOSC|EnsemblGenome=LOC121046893|UniProtKB=A0ACM8G881 A0ACM8G881 LOC121046893 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8025092|UniProtKB=A0ACM8FJP6 A0ACM8FJP6 LOC8025092 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120838358|UniProtKB=A0ACM8EKL7 A0ACM8EKL7 LOC120838358 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120838137|UniProtKB=A0ACM8EK45 A0ACM8EK45 LOC120838137 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120840982|UniProtKB=A0ACM8EQK1 A0ACM8EQK1 LOC120840982 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120845764|UniProtKB=A0ACM8F042 A0ACM8F042 LOC120845764 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030660|UniProtKB=A0ACM8DHC8 A0ACM8DHC8 LOC8030660 PTHR21635:SF1 LEUCINE ZIPPER TRANSCRIPTION FACTOR LIKE LEUCINE ZIPPER TRANSCRIPTION FACTOR-LIKE PROTEIN 1 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC121046479|UniProtKB=A0ACM8FE76 A0ACM8FE76 LOC121046479 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849070|UniProtKB=A0ACM8F6X7 A0ACM8F6X7 LOC120849070 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8036336|UniProtKB=A0ACM8DJX8 A0ACM8DJX8 LOC8036336 PTHR46427:SF1 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 1 STRUCTURE-SPECIFIC ENDONUCLEASE ANKLE1 endonuclease activity#GO:0004519;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;response to stimulus#GO:0050896;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;homologous recombination#GO:0035825;reproductive process#GO:0022414;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC8027345|UniProtKB=A0ACM8DPN6 A0ACM8DPN6 LOC8027345 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 transferase#PC00220 IXOSC|EnsemblGenome=LOC8026854|UniProtKB=A0ACM8FLL6 A0ACM8FLL6 PTHR11963:SF48 LEUCINE AMINOPEPTIDASE-RELATED DIPEPTIDASE B, ISOFORM A catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8050822|UniProtKB=A0ACM8E2J4 A0ACM8E2J4 LOC8050822 PTHR14084:SF0 KYNURENINASE KYNURENINASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115315175|UniProtKB=A0ACM8DUP3 A0ACM8DUP3 LOC115315175 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC115316523|UniProtKB=A0ACM8EJZ4 A0ACM8EJZ4 LOC115316523 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121046562|UniProtKB=A0ACM8FD16 A0ACM8FD16 LOC121046562 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837639|UniProtKB=A0ACM8EHE5 A0ACM8EHE5 LOC120837639 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330539|UniProtKB=A0ACM8EB39 A0ACM8EB39 LOC115330539 PTHR12496:SF9 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25-RELATED RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC120843481|UniProtKB=A0ACM8EXC1 A0ACM8EXC1 LOC120843481 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121833827|UniProtKB=A0ACM8FM27 A0ACM8FM27 LOC121833827 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8039165|UniProtKB=A0ACM8ERY5 A0ACM8ERY5 LOC8039165 PTHR10502:SF247 ANNEXIN ANNEXIN B10 phosphatidylserine binding#GO:0001786;lipid binding#GO:0008289;ion binding#GO:0043167;phospholipid binding#GO:0005543;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;nucleus#GO:0005634;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC121047555|UniProtKB=A0ACM8G566 A0ACM8G566 LOC121047555 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8029178|UniProtKB=A0ACM8E9H4 A0ACM8E9H4 dsh PTHR10878:SF25 SEGMENT POLARITY PROTEIN DISHEVELLED SEGMENT POLARITY PROTEIN DISHEVELLED protein binding#GO:0005515;frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Dsh#P00200;Wnt signaling pathway#P00057>Dishevelled#P01447 IXOSC|EnsemblGenome=LOC115311432|UniProtKB=A0ACM8F8D4 A0ACM8F8D4 LOC115311432 PTHR11177:SF144 CHITINASE CHITINASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115314780|UniProtKB=A0ACM8DU64 A0ACM8DU64 LOC115314780 PTHR12649:SF29 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8031555|UniProtKB=A0ACM8DID6 A0ACM8DID6 LOC8031555 PTHR46095:SF1 ZINC FINGER PROTEIN 593 ZINC FINGER PROTEIN 593 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121833051|UniProtKB=A0ACM8FK70 A0ACM8FK70 LOC121833051 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8030993|UniProtKB=A0ACM8ED18 A0ACM8ED18 LOC8030993 PTHR23048:SF66 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN 2 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115311001|UniProtKB=A0ACM8DQG7 A0ACM8DQG7 LOC115311001 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8024593|UniProtKB=A0ACM8E166 A0ACM8E166 LOC8024593 PTHR46595:SF2 60S RIBOSOMAL PROTEIN L34 LARGE RIBOSOMAL SUBUNIT PROTEIN EL34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121835728|UniProtKB=A0ACM8FWA7 A0ACM8FWA7 LOC121835728 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8030271|UniProtKB=A0ACM8DGJ5 A0ACM8DGJ5 LOC8030271 PTHR12415:SF0 TYROSYL-DNA PHOSPHODIESTERASE 1 TYROSYL-DNA PHOSPHODIESTERASE 1 double-stranded DNA binding#GO:0003690;hydrolase activity#GO:0016787;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC8025287|UniProtKB=A0ACM8DJ55 A0ACM8DJ55 Roc2 PTHR11210:SF60 RING BOX RING-BOX PROTEIN 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941 intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;Cul5-RING ubiquitin ligase complex#GO:0031466;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8028655|UniProtKB=A0ACM8DNB4 A0ACM8DNB4 PIG-O PTHR23071:SF1 PHOSPHATIDYLINOSITOL GLYCAN GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 3, CATALYTIC SUBUNIT catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;gene expression#GO:0010467;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8025613|UniProtKB=A0ACM8FM62 A0ACM8FM62 PTHR15463:SF2 AP1 GAMMA SUBUNIT BINDING PROTEIN 1 SYNERGIN GAMMA trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular vesicle#GO:0097708;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;clathrin vesicle coat#GO:0030125;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;vesicle coat#GO:0030120;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8051509|UniProtKB=A0ACM8DLD6 A0ACM8DLD6 ATPsynE PTHR12427:SF1 ATP SYNTHASE E CHAIN, MITOCHONDRIAL ATP SYNTHASE F(0) COMPLEX SUBUNIT E, MITOCHONDRIAL channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ATP biosynthetic process#GO:0006754;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;respiratory chain complex#GO:0098803;transporter complex#GO:1990351;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ATP synthase#PC00002;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120849932|UniProtKB=A0ACM8F9N5 A0ACM8F9N5 LOC120849932 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120840456|UniProtKB=A0ACM8EPA6 A0ACM8EPA6 LOC120840456 PTHR24255:SF31 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED CUB DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC121837258|UniProtKB=A0ACM8G309 A0ACM8G309 LOC121837258 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035101|UniProtKB=A0ACM8EWY6 A0ACM8EWY6 betaggt-II PTHR11774:SF11 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT BETA transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605 catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8051868|UniProtKB=A0ACM8FLX8 A0ACM8FLX8 LOC8051868 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8043451|UniProtKB=A0ACM8ETG0 A0ACM8ETG0 LOC8043451 PTHR14399:SF5 P53-INDUCED PROTEIN RELATED TRANSMEMBRANE PROTEIN 47 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911 IXOSC|EnsemblGenome=LOC8051489|UniProtKB=A0ACM8EBY2 A0ACM8EBY2 LOC8051489 PTHR11607:SF73 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE 2 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8053444|UniProtKB=A0ACM8E964 A0ACM8E964 LOC8053444 PTHR19957:SF38 SYNTAXIN T-SNARE DOMAIN-CONTAINING PROTEIN 1 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;membrane fusion#GO:0061025;organelle organization#GO:0006996;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737 SNARE protein#PC00034 Parkinson disease#P00049>Syntaxin#P01215;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Synaptic vesicle trafficking#P05734>Syntaxin 1/2#P05772 IXOSC|EnsemblGenome=LOC121838020|UniProtKB=A0ACM8G7J0 A0ACM8G7J0 LOC121838020 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120841164|UniProtKB=A0ACM8ES40 A0ACM8ES40 LOC120841164 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC115309235|UniProtKB=A0ACM8EVC6 A0ACM8EVC6 LOC115309235 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845220|UniProtKB=A0ACM8F198 A0ACM8F198 LOC120845220 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8039108|UniProtKB=A0ACM8DPZ9 A0ACM8DPZ9 PTHR10540:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 7 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome complex#GO:0000502;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 IXOSC|EnsemblGenome=LOC8033657|UniProtKB=A0ACM8EAY9 A0ACM8EAY9 LOC8033657 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;A2-type glycerophospholipase activity#GO:0004623 IXOSC|EnsemblGenome=LOC120841809|UniProtKB=A0ACM8FRS9 A0ACM8FRS9 LOC120841809 PTHR11216:SF178 EH DOMAIN AT21416P protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;transport#GO:0006810;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular component organization#GO:0016043;cilium assembly#GO:0060271;endocytic recycling#GO:0032456;cell projection organization#GO:0030030;endocytosis#GO:0006897;localization within membrane#GO:0051668;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;recycling endosome#GO:0055037;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8024686|UniProtKB=A0ACM8DV82 A0ACM8DV82 Hcs PTHR12835:SF5 BIOTIN PROTEIN LIGASE BIOTIN--PROTEIN LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ligase#PC00142 IXOSC|EnsemblGenome=LOC8028827|UniProtKB=A0ACM8DWL2 A0ACM8DWL2 Prosbeta7 PTHR32194:SF6 METALLOPROTEASE TLDD PROTEASOME SUBUNIT BETA metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8032329|UniProtKB=A0ACM8DJE7 A0ACM8DJE7 LOC8032329 PTHR21231:SF7 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 3 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 small GTPase#PC00208;protein-binding activity modulator#PC00095;G-protein#PC00020 IXOSC|EnsemblGenome=LOC8023674|UniProtKB=A0ACM8DV16 A0ACM8DV16 Atg14 PTHR13664:SF0 BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR BECLIN 1-ASSOCIATED AUTOPHAGY-RELATED KEY REGULATOR molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;kinase regulator activity#GO:0019207;protein-membrane adaptor activity#GO:0043495;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;response to stress#GO:0006950;macroautophagy#GO:0016236;cellular component assembly#GO:0022607;cellular response to nutrient levels#GO:0031669;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;organelle assembly#GO:0070925;organelle localization#GO:0051640;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;cellular component disassembly#GO:0022411 membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;phosphatidylinositol 3-kinase complex, class III#GO:0035032;transferase complex, transferring phosphorus-containing groups#GO:0061695;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;extrinsic component of membrane#GO:0019898 IXOSC|EnsemblGenome=LOC8052617|UniProtKB=A0ACM8G5G1 A0ACM8G5G1 LOC8052617 PTHR44229:SF4 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] CHAIN DEHYDROGENASE_REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02990)-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120840296|UniProtKB=A0ACM8FEA9 A0ACM8FEA9 LOC120840296 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120850812|UniProtKB=A0ACM8F9S6 A0ACM8F9S6 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326588|UniProtKB=A0ACM8EM04 A0ACM8EM04 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034938|UniProtKB=A0ACM8DPN8 A0ACM8DPN8 Tdg PTHR12159:SF9 G/T AND G/U MISMATCH-SPECIFIC DNA GLYCOSYLASE G_T MISMATCH-SPECIFIC THYMINE DNA GLYCOSYLASE catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 base-excision repair#GO:0006284;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA glycosylase#PC00010 IXOSC|EnsemblGenome=LOC120843902|UniProtKB=A0ACM8EWU6 A0ACM8EWU6 LOC120843902 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120839679|UniProtKB=A0ACM8ELS6 A0ACM8ELS6 LOC120839679 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120838798|UniProtKB=A0ACM8EKP6 A0ACM8EKP6 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC121837777|UniProtKB=A0ACM8G646 A0ACM8G646 LOC121837777 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115317254|UniProtKB=A0ACM8EFI9 A0ACM8EFI9 LOC115317254 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8026014|UniProtKB=A0ACM8EI52 A0ACM8EI52 LOC8026014 PTHR20967:SF0 PROHORMONE-4 PROHORMONE-4 IXOSC|EnsemblGenome=LOC115319087|UniProtKB=A0ACM8ES39 A0ACM8ES39 LOC115319087 PTHR16515:SF21 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8042020|UniProtKB=A0ACM8EU59 A0ACM8EU59 LOC8042020 PTHR24320:SF294 RETINOL DEHYDROGENASE NADP-RETINOL DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8038262|UniProtKB=A0ACM8DGT2 A0ACM8DGT2 LOC8038262 PTHR12480:SF19 ARGININE DEMETHYLASE AND LYSYL-HYDROXYLASE JMJD CUPIN-LIKE DOMAIN-CONTAINING PROTEIN 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;sequence-specific DNA binding#GO:0043565;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;DNA binding#GO:0003677;dioxygenase activity#GO:0051213;nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of protein-containing complex disassembly#GO:0043244;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;positive regulation of translation#GO:0045727;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;positive regulation of cellular component organization#GO:0051130 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121046888|UniProtKB=A0ACM8FF34 A0ACM8FF34 LOC121046888 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8028755|UniProtKB=A0ACM8DN44 A0ACM8DN44 LOC8028755 PTHR47399:SF1 TRANSMEMBRANE PROTEIN 121B TRANSMEMBRANE PROTEIN 121B IXOSC|EnsemblGenome=LOC120849754|UniProtKB=A0ACM8G5R2 A0ACM8G5R2 LOC120849754 PTHR12642:SF0 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8037879|UniProtKB=A0ACM8FKJ6 A0ACM8FKJ6 LOC8037879 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115318611|UniProtKB=A0ACM8F1U3 A0ACM8F1U3 LOC115318611 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115312822|UniProtKB=A0ACM8DS86 A0ACM8DS86 LOC115312822 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115314152|UniProtKB=A0ACM8F657 A0ACM8F657 LOC115314152 PTHR18934:SF278 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX34-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8053645|UniProtKB=A0ACM8DQ67 A0ACM8DQ67 LOC8053645 PTHR10890:SF33 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 IXOSC|EnsemblGenome=LOC121835416|UniProtKB=A0ACM8FV08 A0ACM8FV08 LOC121835416 PTHR11214:SF379 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC121833347|UniProtKB=A0ACM8FKN2 A0ACM8FKN2 LOC121833347 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8027641|UniProtKB=A0ACM8DT28 A0ACM8DT28 LOC8027641 PTHR12745:SF6 SUPPRESSION OF TUMORIGENICITY 7 PROTEIN ST7 HOMOLOG IXOSC|EnsemblGenome=LOC8043057|UniProtKB=A0ACM8E8D5 A0ACM8E8D5 LOC8043057 PTHR43655:SF8 ATP-DEPENDENT PROTEASE MITOCHONDRIAL INNER MEMBRANE M-AAA PROTEASE COMPONENT PARAPLEGIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115332269|UniProtKB=A0ACM8EEG0 A0ACM8EEG0 LOC115332269 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837963|UniProtKB=A0ACM8EJF4 A0ACM8EJF4 LOC120837963 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843180|UniProtKB=A0ACM8EVE5 A0ACM8EVE5 LOC120843180 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8038993|UniProtKB=A0ACM8DTE8 A0ACM8DTE8 LOC8038993 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120839696|UniProtKB=A0ACM8FKT9 A0ACM8FKT9 LOC120839696 PTHR45797:SF1 RAD54-LIKE HELICASE ARIP4 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;transcription regulator activity#GO:0140110 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121832961|UniProtKB=A0ACM8FXY9 A0ACM8FXY9 LOC121832961 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120836363|UniProtKB=A0ACM8EFS6 A0ACM8EFS6 LOC120836363 PTHR18934:SF278 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX34-RELATED ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;isomerase activity#GO:0016853;helicase activity#GO:0004386 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8028320|UniProtKB=A0ACM8EB37 A0ACM8EB37 LOC8028320 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 IXOSC|EnsemblGenome=LOC121836362|UniProtKB=A0ACM8G3P7 A0ACM8G3P7 LOC121837131 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115328754|UniProtKB=A0ACM8DMC0 A0ACM8DMC0 LOC115328754 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC8043175|UniProtKB=A0ACM8E3X7 A0ACM8E3X7 LOC8043175 PTHR22967:SF107 SERINE/THREONINE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;positive regulation of Notch signaling pathway#GO:0045747;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8053920|UniProtKB=A0ACM8DYL1 A0ACM8DYL1 Mhc PTHR45615:SF86 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN, MUSCLE protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;polypeptide conformation or assembly isomerase activity#GO:0120544;actin binding#GO:0003779;actin filament binding#GO:0051015;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;cytoskeletal protein binding#GO:0008092;macromolecular conformation isomerase activity#GO:0120543 muscle system process#GO:0003012;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;actomyosin structure organization#GO:0031032;cell development#GO:0048468;cell differentiation#GO:0030154;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular anatomical entity morphogenesis#GO:0032989;striated muscle cell differentiation#GO:0051146;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization or biogenesis#GO:0071840;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;muscle cell development#GO:0055001;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;sarcomere organization#GO:0045214;actin filament-based process#GO:0030029;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;supramolecular fiber organization#GO:0097435;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;muscle contraction#GO:0006936;developmental process#GO:0032502;system process#GO:0003008;cellular developmental process#GO:0048869 organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC8052038|UniProtKB=A0ACM8DLG7 A0ACM8DLG7 LOC8052038 PTHR19857:SF27 MITOCHONDRIAL DIVISION PROTEIN 1-RELATED ANGIO-ASSOCIATED MIGRATORY CELL PROTEIN molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;cell adhesion#GO:0007155;cell motility#GO:0048870;cell migration#GO:0016477 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 IXOSC|EnsemblGenome=LOC8041287|UniProtKB=A0ACM8ECR3 A0ACM8ECR3 LOC8041287 PTHR12827:SF3 MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER ANAPHASE-PROMOTING COMPLEX SUBUNIT 1 regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of cellular component organization#GO:0051128;protein polyubiquitination#GO:0000209;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;protein K11-linked ubiquitination#GO:0070979;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;regulation of chromosome segregation#GO:0051983;metaphase/anaphase transition of cell cycle#GO:0044784;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;cell cycle#GO:0007049;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;mitotic cell cycle phase transition#GO:0044772;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8043544|UniProtKB=A0ACM8DGN7 A0ACM8DGN7 LOC8043544 PTHR23254:SF15 EIF4G DOMAIN PROTEIN POLYADENYLATE-BINDING PROTEIN-INTERACTING PROTEIN 1 translation regulator activity#GO:0045182 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of translational initiation#GO:0006446;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121047679|UniProtKB=A0ACM8FGK4 A0ACM8FGK4 LOC121047679 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120836177|UniProtKB=A0ACM8F8T4 A0ACM8F8T4 LOC120836177 PTHR23287:SF18 RUBY-EYE2-LIKE PROTEIN BLOC-2 COMPLEX MEMBER HPS5 pigmentation#GO:0043473;developmental pigmentation#GO:0048066 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120851038|UniProtKB=A0ACM8FBD4 A0ACM8FBD4 LOC120851038 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045559|UniProtKB=A0ACM8FBN5 A0ACM8FBN5 LOC121045559 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051554|UniProtKB=A0ACM8DLY3 A0ACM8DLY3 wbl PTHR12211:SF3 ENDOPLASMIC RETICULUM PROTEIN ERP29 PROTEIN WINDBEUTEL protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120842156|UniProtKB=A0ACM8ET86 A0ACM8ET86 LOC120842156 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846365|UniProtKB=A0ACM8F1Y4 A0ACM8F1Y4 LOC120846365 PTHR21586:SF0 TIPA PP2C-LIKE DOMAIN-CONTAINING PROTEIN CG9801 IXOSC|EnsemblGenome=LOC115332251|UniProtKB=A0ACM8F7X8 A0ACM8F7X8 LOC115332251 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115320132|UniProtKB=A0ACM8EZ19 A0ACM8EZ19 LOC115320132 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332264|UniProtKB=A0ACM8G1U6 A0ACM8G1U6 LOC115332264 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8038225|UniProtKB=A0ACM8FFN2 A0ACM8FFN2 LOC8038225 PTHR24289:SF24 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 21-HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824 ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;hormone metabolic process#GO:0042445;hormone biosynthetic process#GO:0042446;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;biological regulation#GO:0065007;metabolic process#GO:0008152;olefinic compound metabolic process#GO:0120254;lipid metabolic process#GO:0006629;regulation of biological quality#GO:0065008 IXOSC|EnsemblGenome=LOC115323808|UniProtKB=A0ACM8E4I5 A0ACM8E4I5 LOC115323808 PTHR13049:SF2 DUF814-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN 25 IXOSC|EnsemblGenome=LOC8041764|UniProtKB=A0ACM8DNJ3 A0ACM8DNJ3 LOC8041764 PTHR24067:SF248 UBIQUITIN-CONJUGATING ENZYME E2 DORSAL INTERACTING PROTEIN 4 ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein sumoylation#GO:0016925 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8053511|UniProtKB=A0ACM8DNS6 A0ACM8DNS6 LOC8053511 PTHR22897:SF8 QUIESCIN Q6-RELATED SULFHYDRYL OXIDASE SULFHYDRYL OXIDASE disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 extracellular structure organization#GO:0043062;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein folding#GO:0006457;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;extracellular matrix assembly#GO:0085029;gene expression#GO:0010467;protein maturation#GO:0051604;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC120842779|UniProtKB=A0ACM8EVN8 A0ACM8EVN8 LOC120842779 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8035185|UniProtKB=A0ACM8E6V5 A0ACM8E6V5 eIF3a PTHR14005:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, THETA SUBUNIT EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 cytosol#GO:0005829;eukaryotic translation initiation factor 3 complex#GO:0005852;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8042382|UniProtKB=A0ACM8DKW4 A0ACM8DKW4 LOC8042382 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC121836764|UniProtKB=A0ACM8G0H4 A0ACM8G0H4 LOC121836764 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8031921|UniProtKB=A0ACM8FT54 A0ACM8FT54 LOC8031921 PTHR12577:SF6 DACHSHUND DACHSHUND, ISOFORM B binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC121834428|UniProtKB=A0ACM8FPM9 A0ACM8FPM9 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8053429|UniProtKB=A0ACM8DLV7 A0ACM8DLV7 Roc1a PTHR11210:SF2 RING BOX E3 UBIQUITIN-PROTEIN LIGASE RBX1 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121834841|UniProtKB=A0ACM8FSJ2 A0ACM8FSJ2 LOC121834841 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8038400|UniProtKB=A0ACM8ENN5 A0ACM8ENN5 LOC8038400 PTHR43725:SF58 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 epimerase/racemase#PC00096 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 IXOSC|EnsemblGenome=LOC115327205|UniProtKB=A0ACM8E863 A0ACM8E863 zip PTHR45615:SF40 MYOSIN HEAVY CHAIN, NON-MUSCLE MYOSIN HEAVY CHAIN, NON-MUSCLE actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;organelle#GO:0043226;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Myosin#P00867;Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097;Cytoskeletal regulation by Rho GTPase#P00016>Myosin#P00522 IXOSC|EnsemblGenome=LOC121047198|UniProtKB=A0ACM8FFX8 A0ACM8FFX8 LOC121047198 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter#PC00227 IXOSC|EnsemblGenome=LOC8029784|UniProtKB=A0ACM8DSB8 A0ACM8DSB8 LOC8029784 PTHR11226:SF0 UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;catalytic activity#GO:0003824;transferase activity#GO:0016740;glucosyltransferase activity#GO:0046527;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120851103|UniProtKB=A0ACM8FB41 A0ACM8FB41 PTHR47972:SF45 KINESIN-LIKE PROTEIN KLP-3 PROTEIN CLARET SEGREGATIONAL microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC115332754|UniProtKB=A0ACM8EZY7 A0ACM8EZY7 LOC115332754 PTHR22988:SF71 MYOTONIC DYSTROPHY S/T KINASE-RELATED CITRON RHO-INTERACTING KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin polymerization or depolymerization#GO:0008064;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of biological quality#GO:0065008;actin filament-based process#GO:0030029;regulation of actin filament length#GO:0030832;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;actomyosin structure organization#GO:0031032;cellular component organization#GO:0016043;cell cycle#GO:0007049;regulation of organelle organization#GO:0033043;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115318485|UniProtKB=A0ACM8FHF7 A0ACM8FHF7 LOC115318485 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120839112|UniProtKB=A0ACM8ELB0 A0ACM8ELB0 LOC120839112 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8030427|UniProtKB=A0ACM8E3K6 A0ACM8E3K6 LOC8030427 PTHR47219:SF26 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE GROWTH HORMONE-REGULATED TBC PROTEIN 1 molecular function activator activity#GO:0140677;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;enzyme binding#GO:0019899;binding#GO:0005488;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC120843001|UniProtKB=A0ACM8EUX9 A0ACM8EUX9 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035754|UniProtKB=A0ACM8EJX1 A0ACM8EJX1 LOC8035754 PTHR19924:SF26 UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase I#GO:0045943;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA processing factor#PC00147;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8036662|UniProtKB=A0ACM8EEM6 A0ACM8EEM6 LOC8036662 PTHR11071:SF581 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115316448|UniProtKB=A0ACM8EM59 A0ACM8EM59 LOC115316448 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846754|UniProtKB=A0ACM8F402 A0ACM8F402 PIG-S PTHR21072:SF13 GPI TRANSAMIDASE COMPONENT PIG-S GPI-ANCHOR TRANSAMIDASE COMPONENT PIGS protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;caspase complex#GO:0008303;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC121836602|UniProtKB=A0ACM8G0L6 A0ACM8G0L6 LOC121837299 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052214|UniProtKB=A0ACM8FVH9 A0ACM8FVH9 LOC8052214 PTHR24366:SF165 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS LEUCINE-RICH TENDON-SPECIFIC PROTEIN, ISOFORM C immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121048298|UniProtKB=A0ACM8FHV5 A0ACM8FHV5 LOC121048298 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121834566|UniProtKB=A0ACM8FRB0 A0ACM8FRB0 PTHR43243:SF108 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER 4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171 amino acid transport#GO:0006865;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 amino acid transporter#PC00046;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115322028|UniProtKB=A0ACM8E1K8 A0ACM8E1K8 LOC115322028 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115332909|UniProtKB=A0ACM8G8U7 A0ACM8G8U7 LOC115332909 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115325484|UniProtKB=A0ACM8E4W3 A0ACM8E4W3 Bdbt PTHR46512:SF10 PEPTIDYLPROLYL ISOMERASE FK506-BINDING PROTEIN-LIKE chaperone#PC00072 IXOSC|EnsemblGenome=LOC8023694|UniProtKB=A0ACM8E0U4 A0ACM8E0U4 LOC8023694 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 IXOSC|EnsemblGenome=LOC121835137|UniProtKB=A0ACM8FTL2 A0ACM8FTL2 LOC121835137 PTHR10339:SF32 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5-RELATED glycosyltransferase activity#GO:0016757;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 transferase#PC00220 IXOSC|EnsemblGenome=LOC115318975|UniProtKB=A0ACM8DZ36 A0ACM8DZ36 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120849080|UniProtKB=A0ACM8F7C0 A0ACM8F7C0 LOC120849080 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=ISCI020559|UniProtKB=B7PZ18 B7PZ18 ISCW020559 PTHR15004:SF0 GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C, MITOCHONDRIAL amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115327227|UniProtKB=A0ACM8EJ70 A0ACM8EJ70 LOC115327227 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115316699|UniProtKB=A0ACM8F9K2 A0ACM8F9K2 LOC115316699 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025367|UniProtKB=A0ACM8FWD3 A0ACM8FWD3 LOC8025367 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8043947|UniProtKB=A0ACM8DL67 A0ACM8DL67 Rrp42 PTHR11097:SF8 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP42 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC115309538|UniProtKB=A0ACM8EWQ8 A0ACM8EWQ8 LOC115309538 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316220|UniProtKB=A0ACM8G810 A0ACM8G810 LOC115316220 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;sodium ion transport#GO:0006814 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8044011|UniProtKB=A0ACM8DL70 A0ACM8DL70 LOC8044011 PTHR15231:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT H glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8043990|UniProtKB=A0ACM8DV47 A0ACM8DV47 LOC8043990 PTHR45867:SF3 PURPLE ACID PHOSPHATASE ACID PHOSPHATASE TYPE 7 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8032203|UniProtKB=A0ACM8DJA2 A0ACM8DJA2 LOC8032203 PTHR13387:SF9 PROTEIN HGH1 HOMOLOG CO-CHAPERONE PROTEIN HGH1 HOMOLOG IXOSC|EnsemblGenome=LOC8039560|UniProtKB=A0ACM8DZQ2 A0ACM8DZQ2 LOC8039560 PTHR16291:SF0 NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3 NUCLEAR CAP-BINDING PROTEIN SUBUNIT 3 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8034383|UniProtKB=A0ACM8DJ91 A0ACM8DJ91 LOC8034383 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8026444|UniProtKB=A0ACM8FUQ3 A0ACM8FUQ3 Mtr4 PTHR12131:SF7 ATP-DEPENDENT RNA AND DNA HELICASE EXOSOME RNA HELICASE MTR4 macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120840011|UniProtKB=A0ACM8EN92 A0ACM8EN92 LOC120840011 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC121833169|UniProtKB=A0ACM8FIH0 A0ACM8FIH0 LOC8029216 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115321914|UniProtKB=A0ACM8E2B3 A0ACM8E2B3 milt PTHR15751:SF12 TRAFFICKING KINESIN-BINDING PROTEIN TRAFFICKING KINESIN-BINDING PROTEIN MILT cytoskeletal protein binding#GO:0008092;binding#GO:0005488;myosin binding#GO:0017022;protein binding#GO:0005515 organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;microtubule-based process#GO:0007017;mitochondrion localization#GO:0051646;vesicle cytoskeletal trafficking#GO:0099518;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;protein targeting#GO:0006605;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle localization#GO:0051640 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;mitochondrion#GO:0005739 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120841258|UniProtKB=A0ACM8ERF5 A0ACM8ERF5 LOC120841258 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120836654|UniProtKB=A0ACM8EF55 A0ACM8EF55 LOC120836654 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322282|UniProtKB=A0ACM8EQR2 A0ACM8EQR2 LOC115322282 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115327968|UniProtKB=A0ACM8F5K2 A0ACM8F5K2 LOC115327968 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8029315|UniProtKB=A0ACM8EBA5 A0ACM8EBA5 Mlf PTHR13105:SF24 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8025680|UniProtKB=A0ACM8E616 A0ACM8E616 LOC8025680 PTHR21049:SF0 RIBOPHORIN I DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT 1 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101 endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8037945|UniProtKB=A0ACM8FY95 A0ACM8FY95 LOC8037945 PTHR23354:SF132 NUCLEOLAR PROTEIN 7/ESTROGEN RECEPTOR COACTIVATOR-RELATED OXIDATION RESISTANCE PROTEIN 1 response to stress#GO:0006950;response to stimulus#GO:0050896;response to oxidative stress#GO:0006979 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8023665|UniProtKB=A0ACM8FRY3 A0ACM8FRY3 Nulp1 PTHR22684:SF0 NULP1-RELATED RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT TCF25 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8023110|UniProtKB=A0ACM8E979 A0ACM8E979 LOC8023110 PTHR15976:SF18 CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA CONSTITUTIVE COACTIVATOR OF PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA IXOSC|EnsemblGenome=LOC115309966|UniProtKB=A0ACM8EIN7 A0ACM8EIN7 LOC115309966 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849427|UniProtKB=A0ACM8FIN9 A0ACM8FIN9 LOC120849427 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121047443|UniProtKB=A0ACM8G8Y7 A0ACM8G8Y7 LOC121047443 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8034406|UniProtKB=A0ACM8DJ98 A0ACM8DJ98 LOC8034406 PTHR11266:SF8 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MPV17-LIKE PROTEIN 2 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transporter#PC00227 IXOSC|EnsemblGenome=LOC8036655|UniProtKB=A0ACM8DYM3 A0ACM8DYM3 Sqor PTHR10632:SF2 SULFIDE:QUINONE OXIDOREDUCTASE SULFIDE:QUINONE OXIDOREDUCTASE, MITOCHONDRIAL oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8039320|UniProtKB=A0ACM8E4T1 A0ACM8E4T1 LOC8039320 PTHR24067:SF257 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 6 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115332076|UniProtKB=A0ACM8EYE7 A0ACM8EYE7 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8052017|UniProtKB=A0ACM8DLF2 A0ACM8DLF2 RASSF8 PTHR15286:SF6 RAS-ASSOCIATING DOMAIN CONTAINING PROTEIN GH01133P scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120838971|UniProtKB=A0ACM8EM18 A0ACM8EM18 LOC120838971 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309431|UniProtKB=A0ACM8FDM3 A0ACM8FDM3 PTHR15138:SF14 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;Huntington disease#P00029>TAFII130#P00806;General transcription regulation#P00023>TBP-associated factors#P00658 IXOSC|EnsemblGenome=LOC120849685|UniProtKB=A0ACM8FND1 A0ACM8FND1 PTHR34524:SF6 CALCYPHOSIN CALCYPHOSINE LIKE calcium-binding protein#PC00060;calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8053586|UniProtKB=A0ACM8DL96 A0ACM8DL96 LOC8053586 PTHR24173:SF92 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG B ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115324219|UniProtKB=A0ACM8E4Y8 A0ACM8E4Y8 LOC115324219 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120849147|UniProtKB=A0ACM8F694 A0ACM8F694 LOC120849147 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115319778|UniProtKB=A0ACM8ENL5 A0ACM8ENL5 LOC115319778 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC115320102|UniProtKB=A0ACM8ETR4 A0ACM8ETR4 LOC115320102 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8043097|UniProtKB=A0ACM8EE95 A0ACM8EE95 Taf11 PTHR13218:SF8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11-RELATED TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 11 transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 IXOSC|EnsemblGenome=LOC120848224|UniProtKB=A0ACM8F5A3 A0ACM8F5A3 LOC120848224 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8035528|UniProtKB=A0ACM8E2G3 A0ACM8E2G3 Mat1 PTHR12683:SF13 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 CDK-ACTIVATING KINASE ASSEMBLY FACTOR MAT1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 RNA metabolic process#GO:0016070;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367 transferase complex#GO:1990234;transcription regulator complex#GO:0005667;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120848673|UniProtKB=A0ACM8F651 A0ACM8F651 LOC120848673 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031802|UniProtKB=A0ACM8E588 A0ACM8E588 LOC8031802 PTHR10332:SF88 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 1, ISOFORM A carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC120850511|UniProtKB=A0ACM8FAC1 A0ACM8FAC1 LOC120850511 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842125|UniProtKB=A0ACM8ET39 A0ACM8ET39 LOC120842125 PTHR12360:SF16 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 TRANSCRIPTIONAL REPRESSOR NF-X1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120839672|UniProtKB=A0ACM8EMI7 A0ACM8EMI7 LOC120839672 PTHR44490:SF1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209;enzyme activator activity#GO:0008047 positive regulation of apoptotic process#GO:0043065;regulation of response to stress#GO:0080134;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of signaling#GO:0023056;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222;translation factor#PC00223 IXOSC|EnsemblGenome=LOC115329812|UniProtKB=A0ACM8ER61 A0ACM8ER61 LOC115329812 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120840737|UniProtKB=A0ACM8EQ52 A0ACM8EQ52 LOC120840737 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320248|UniProtKB=A0ACM8EZ54 A0ACM8EZ54 LOC115320248 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120837349|UniProtKB=A0ACM8EH47 A0ACM8EH47 LOC120837349 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8052841|UniProtKB=A0ACM8EP00 A0ACM8EP00 LOC8052841 PTHR46708:SF2 TENASCIN FIBRONECTIN-LIKE extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC120840578|UniProtKB=A0ACM8EPI9 A0ACM8EPI9 LOC120840578 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8026417|UniProtKB=A0ACM8DHQ5 A0ACM8DHQ5 Sf3a2 PTHR23205:SF0 SPLICING FACTOR 3A SUBUNIT 2 SPLICING FACTOR 3A SUBUNIT 2 cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;U2-type prespliceosome#GO:0071004;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121837525|UniProtKB=A0ACM8G3G1 A0ACM8G3G1 LOC121837525 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8026253|UniProtKB=A0ACM8DHF2 A0ACM8DHF2 Ski6 PTHR11953:SF0 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP41 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;rRNA metabolic process#GO:0016072;RNA catabolic process#GO:0006401;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC115322193|UniProtKB=A0ACM8G0H7 A0ACM8G0H7 LOC115322193 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC115308598|UniProtKB=A0ACM8DMT0 A0ACM8DMT0 LOC115308598 PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 lysosome#GO:0005764;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC120840899|UniProtKB=A0ACM8ERG9 A0ACM8ERG9 LOC120840899 PTHR22948:SF50 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121834663|UniProtKB=A0ACM8FQC3 A0ACM8FQC3 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053606|UniProtKB=A0ACM8G0Y6 A0ACM8G0Y6 Ocrl PTHR11200:SF303 INOSITOL 5-PHOSPHATASE EG:86E4.5 PROTEIN catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8053165|UniProtKB=A0ACM8DRG2 A0ACM8DRG2 LOC8053165 PTHR31526:SF2 SOSS COMPLEX SUBUNIT C SOSS COMPLEX SUBUNIT C response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC120850508|UniProtKB=A0ACM8F8X2 A0ACM8F8X2 LOC120850508 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115320943|UniProtKB=A0ACM8E1H6 A0ACM8E1H6 Prosalpha6 PTHR11599:SF244 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-1 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 IXOSC|EnsemblGenome=LOC8040255|UniProtKB=A0ACM8DKJ2 A0ACM8DKJ2 LOC8040255 PTHR46194:SF1 PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED PEPTIDYL-TRNA HYDROLASE PTRHD1-RELATED IXOSC|EnsemblGenome=LOC115324176|UniProtKB=A0ACM8G4G0 A0ACM8G4G0 LOC115324176 PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115320035|UniProtKB=A0ACM8FLA1 A0ACM8FLA1 LOC115320035 PTHR10830:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115320079|UniProtKB=A0ACM8EKH7 A0ACM8EKH7 LOC115320079 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8024801|UniProtKB=A0ACM8DIQ7 A0ACM8DIQ7 RpL9 PTHR11655:SF16 60S/50S RIBOSOMAL PROTEIN L6/L9 LARGE RIBOSOMAL SUBUNIT PROTEIN UL6 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467 cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121835274|UniProtKB=A0ACM8FSZ7 A0ACM8FSZ7 LOC121835274 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023681|UniProtKB=A0ACM8DHD7 A0ACM8DHD7 LOC8023681 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120835961|UniProtKB=A0ACM8ET62 A0ACM8ET62 LOC120835961 PTHR10609:SF28 BIOTINIDASE-RELATED CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121837632|UniProtKB=A0ACM8G5P2 A0ACM8G5P2 LOC121837632 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115321253|UniProtKB=A0ACM8ETJ9 A0ACM8ETJ9 LOC115321253 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8030686|UniProtKB=A0ACM8E039 A0ACM8E039 LOC8030686 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121836796|UniProtKB=A0ACM8G0N4 A0ACM8G0N4 LOC121836796 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043313|UniProtKB=A0ACM8FT42 A0ACM8FT42 mdlc PTHR12930:SF0 ZINC FINGER PROTEIN 183 RING FINGER PROTEIN 113A1 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115309944|UniProtKB=A0ACM8DPA4 A0ACM8DPA4 LOC115309944 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041415|UniProtKB=A0ACM8EC63 A0ACM8EC63 Bin1 PTHR13082:SF0 SAP18 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP18 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 Hedgehog signaling pathway#P00025>Sap18#P00697 IXOSC|EnsemblGenome=LOC115332852|UniProtKB=A0ACM8EDR0 A0ACM8EDR0 LOC115332852 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;monoatomic cation transmembrane transporter activity#GO:0008324 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8030682|UniProtKB=A0ACM8FB53 A0ACM8FB53 PTHR38337:SF1 AGAP010540-PA GUSTATORY RECEPTOR-LIKE HOLOZOA, ISOFORM C IXOSC|EnsemblGenome=LOC120837788|UniProtKB=A0ACM8EHT1 A0ACM8EHT1 LOC120837788 PTHR43561:SF3 FAMILY NOT NAMED HYDROXYACYL-COENZYME A DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;monocarboxylic acid catabolic process#GO:0072329;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid modification#GO:0030258;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440 IXOSC|EnsemblGenome=LOC8052971|UniProtKB=A0ACM8ER50 A0ACM8ER50 LOC8052971 PTHR24253:SF153 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8034249|UniProtKB=A0ACM8DJ48 A0ACM8DJ48 Bug22 PTHR12458:SF11 ORF PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 20 sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;organelle assembly#GO:0070925;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;microtubule-based movement#GO:0007018;cell motility#GO:0048870;spermatogenesis#GO:0007283;developmental process#GO:0032502;flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;sperm axoneme assembly#GO:0007288;cellular developmental process#GO:0048869;plasma membrane bounded cell projection organization#GO:0120036;male gamete generation#GO:0048232;multicellular organismal process#GO:0032501;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;spermatid differentiation#GO:0048515;cilium organization#GO:0044782;sperm flagellum assembly#GO:0120316;cilium-dependent cell motility#GO:0060285;anatomical structure morphogenesis#GO:0009653;sperm motility#GO:0097722;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;gamete generation#GO:0007276;anatomical structure formation involved in morphogenesis#GO:0048646;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275;motile cilium assembly#GO:0044458;cellular component organization or biogenesis#GO:0071840;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 cilium#GO:0005929;9+2 motile cilium#GO:0097729;intracellular organelle#GO:0043229;axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;cytoplasmic microtubule#GO:0005881;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;motile cilium#GO:0031514;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;sperm flagellum#GO:0036126;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 IXOSC|EnsemblGenome=LOC120841833|UniProtKB=A0ACM8ES74 A0ACM8ES74 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844156|UniProtKB=A0ACM8EXN7 A0ACM8EXN7 LOC120844156 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115324994|UniProtKB=A0ACM8E4G8 A0ACM8E4G8 LOC115324994 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115324771|UniProtKB=A0ACM8E5H6 A0ACM8E5H6 LOC115324771 PTHR12669:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN translation initiation factor binding#GO:0031369;protein binding#GO:0005515;translation regulator activity#GO:0045182;binding#GO:0005488 negative regulation of translation#GO:0017148;regulation of translational initiation#GO:0006446;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 translation factor#PC00223;translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120844671|UniProtKB=A0ACM8FGS8 A0ACM8FGS8 LOC120844671 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121047338|UniProtKB=A0ACM8FEP9 A0ACM8FEP9 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120850425|UniProtKB=A0ACM8FA49 A0ACM8FA49 LOC120850425 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120845763|UniProtKB=A0ACM8F0S5 A0ACM8F0S5 LOC120845763 PTHR21230:SF89 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1B binding#GO:0005488;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;protein binding#GO:0005515;SNAP receptor activity#GO:0005484 Golgi to vacuole transport#GO:0006896;localization#GO:0051179;intra-Golgi vesicle-mediated transport#GO:0006891;Golgi organization#GO:0007030;catabolic process#GO:0009056;vesicle fusion#GO:0006906;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;membrane fusion#GO:0061025;retrograde transport, endosome to Golgi#GO:0042147;macroautophagy#GO:0016236;membrane organization#GO:0061024;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;post-Golgi vesicle-mediated transport#GO:0006892;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;metabolic process#GO:0008152;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;endosomal transport#GO:0016197;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular vesicle#GO:0097708;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasm#GO:0005737;bounding membrane of organelle#GO:0098588;late endosome membrane#GO:0031902;endoplasmic reticulum#GO:0005783;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vesicle#GO:0031982;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endoplasmic reticulum subcompartment#GO:0098827;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;vesicle membrane#GO:0012506;membrane#GO:0016020;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;ER to Golgi transport vesicle membrane#GO:0012507 membrane traffic protein#PC00150;SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 IXOSC|EnsemblGenome=LOC8051363|UniProtKB=A0ACM8FFW2 A0ACM8FFW2 LOC8051363 PTHR22255:SF9 LP06548P CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR IXOSC|EnsemblGenome=LOC8042525|UniProtKB=A0ACM8DKV2 A0ACM8DKV2 LOC8042525 PTHR10366:SF848 NAD DEPENDENT EPIMERASE/DEHYDRATASE 3-BETA HYDROXYSTEROID DEHYDROGENASE_ISOMERASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115321525|UniProtKB=A0ACM8E165 A0ACM8E165 PTHR46814:SF1 EGALITARIAN, ISOFORM B EGALITARIAN, ISOFORM B mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA localization#GO:0006403;localization#GO:0051179;macromolecule localization#GO:0033036 IXOSC|EnsemblGenome=LOC115323256|UniProtKB=A0ACM8EFZ9 A0ACM8EFZ9 LOC115323256 PTHR42643:SF51 IONOTROPIC RECEPTOR 20A-RELATED SUBFAMILY NOT NAMED transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8052002|UniProtKB=A0ACM8DYV0 A0ACM8DYV0 LOC8052002 PTHR21240:SF27 2-AMINO-3-CARBOXYLMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE 2-AMINO-3-CARBOXYMUCONATE-6-SEMIALDEHYDE DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831 secondary metabolic process#GO:0019748;metabolic process#GO:0008152;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8042442|UniProtKB=A0ACM8E246 A0ACM8E246 PCID2 PTHR12732:SF0 UNCHARACTERIZED PROTEASOME COMPONENT REGION PCI-CONTAINING PCI DOMAIN-CONTAINING PROTEIN 2 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;RNA binding#GO:0003723 macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transcription by RNA polymerase II#GO:0006366;transport#GO:0006810;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;chromosome organization#GO:0051276;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound transport#GO:0015931;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;DNA-templated transcription#GO:0006351;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;organelle organization#GO:0006996;DNA-templated transcription elongation#GO:0006354;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;nucleic acid biosynthetic process#GO:0141187;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC121047015|UniProtKB=A0ACM8FFA2 A0ACM8FFA2 LOC121047015 PTHR10283:SF136 SOLUTE CARRIER FAMILY 13 MEMBER SOLUTE CARRIER FAMILY 13 MEMBER 2-LIKE ISOFORM X1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC121833887|UniProtKB=A0ACM8FPF3 A0ACM8FPF3 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8035570|UniProtKB=A0ACM8DR84 A0ACM8DR84 LOC8035570 PTHR23345:SF15 VITELLOGENIN-RELATED VITELLOGENIN-6 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 storage protein#PC00210 IXOSC|EnsemblGenome=LOC120846882|UniProtKB=A0ACM8FYM6 A0ACM8FYM6 LOC120846882 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115309204|UniProtKB=A0ACM8F9X2 A0ACM8F9X2 LOC115309204 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8037072|UniProtKB=A0ACM8ECR0 A0ACM8ECR0 LOC8037072 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC121046961|UniProtKB=A0ACM8FG76 A0ACM8FG76 LOC121046961 PTHR23080:SF63 THAP DOMAIN PROTEIN DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053851|UniProtKB=A0ACM8FKK5 A0ACM8FKK5 LOC8053851 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;RNA metabolic process#GO:0016070;regulation of protein metabolic process#GO:0051246;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 IXOSC|EnsemblGenome=LOC115318472|UniProtKB=A0ACM8FAG2 A0ACM8FAG2 LOC115318472 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE-LIKE transferase#PC00220 IXOSC|EnsemblGenome=LOC8042184|UniProtKB=A0ACM8FML4 A0ACM8FML4 LOC8042184 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC120844510|UniProtKB=A0ACM8EYT2 A0ACM8EYT2 LOC120844510 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC121833090|UniProtKB=A0ACM8FKC1 A0ACM8FKC1 LOC121833090 PTHR31684:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 IXOSC|EnsemblGenome=LOC120841074|UniProtKB=A0ACM8EQP7 A0ACM8EQP7 LOC120841074 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 IXOSC|EnsemblGenome=LOC8028742|UniProtKB=A0ACM8DH67 A0ACM8DH67 NP15.6 PTHR13327:SF0 NADH-UBIQUINONE OXIDOREDUCTASE ESSS SUBUNIT, MITOCHONDRIAL PRECURSOR NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 11, MITOCHONDRIAL respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121833198|UniProtKB=A0ACM8FJY2 A0ACM8FJY2 LOC121833198 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036503|UniProtKB=A0ACM8DU97 A0ACM8DU97 LOC8036503 PTHR46182:SF2 FI19480P1 FI19480P1 cellular process#GO:0009987;cell differentiation#GO:0030154;cell motility#GO:0048870;cell migration#GO:0016477;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;generation of neurons#GO:0048699;multicellular organism development#GO:0007275;neuron migration#GO:0001764;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;system development#GO:0048731;neurogenesis#GO:0022008 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8029264|UniProtKB=A0ACM8DTI4 A0ACM8DTI4 LOC8029264 PTHR15704:SF7 SUPERKILLER 3 PROTEIN-RELATED SUPERKILLER COMPLEX PROTEIN 3 catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8043250|UniProtKB=A0ACM8E9U1 A0ACM8E9U1 LOC8043250 PTHR14440:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase I promoter#GO:0006361;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535 DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC8037483|UniProtKB=A0ACM8FLE7 A0ACM8FLE7 LOC8037483 PTHR12449:SF22 DEATH DOMAIN-CONTAINING PROTEIN NUCLEOLAR PROTEIN 4-LIKE ISOFORM X1 IXOSC|EnsemblGenome=LOC8050437|UniProtKB=A0ACM8DZ16 A0ACM8DZ16 lt PTHR12616:SF1 VACUOLAR PROTEIN SORTING VPS41 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;vesicle fusion#GO:0006906;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;response to stress#GO:0006950;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;macroautophagy#GO:0016236;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;transport#GO:0006810;cellular response to nutrient levels#GO:0031669;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle tethering complex#GO:0099023;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8053402|UniProtKB=A0ACM8DT46 A0ACM8DT46 LOC8053402 PTHR31701:SF3 ENDOPLASMIC RETICULUM MEMBRANE-ASSOCIATED RNA DEGRADATION PROTEIN ENDOPLASMIC RETICULUM MEMBRANE-ASSOCIATED RNA DEGRADATION PROTEIN N-TERMINAL DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8051408|UniProtKB=A0ACM8F3B8 A0ACM8F3B8 LOC8051408 PTHR28644:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 15 SMALL INTEGRAL MEMBRANE PROTEIN 15 IXOSC|EnsemblGenome=LOC8023134|UniProtKB=A0ACM8E8L2 A0ACM8E8L2 LOC8023134 PTHR10073:SF52 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MISMATCH REPAIR ENDONUCLEASE PMS2 ISOFORM X1 DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520 nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;mismatch repair#GO:0006298;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115312865|UniProtKB=A0ACM8DS95 A0ACM8DS95 LOC115312865 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115316924|UniProtKB=A0ACM8DWG1 A0ACM8DWG1 LOC115316924 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026335|UniProtKB=A0ACM8DMR4 A0ACM8DMR4 LOC8026335 PTHR16172:SF46 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE GH27779P cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8030236|UniProtKB=A0ACM8E2M3 A0ACM8E2M3 LOC8030236 PTHR21308:SF1 PHYTANOYL-COA ALPHA-HYDROXYLASE PHYTANOYL-COA DIOXYGENASE, PEROXISOMAL 2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120848609|UniProtKB=A0ACM8F719 A0ACM8F719 LOC120848609 PTHR37456:SF8 SI:CH211-266K2.1 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8042335|UniProtKB=A0ACM8EAH4 A0ACM8EAH4 LOC8042335 PTHR10217:SF642 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN EAG voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8053420|UniProtKB=A0ACM8E454 A0ACM8E454 Mtmr6 PTHR10807:SF134 MYOTUBULARIN-RELATED PHOSPHATIDYLINOSITOL-3,5-BISPHOSPHATE 3-PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311;lipid modification#GO:0030258 membrane#GO:0016020;cellular anatomical structure#GO:0110165 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8054046|UniProtKB=A0ACM8DXB0 A0ACM8DXB0 Adar PTHR10910:SF62 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN AT07585P-RELATED double-stranded RNA binding#GO:0003725;tRNA-specific adenosine deaminase activity#GO:0008251;binding#GO:0005488;nucleic acid binding#GO:0003676;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;RNA binding#GO:0003723;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;base conversion or substitution editing#GO:0016553;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;adenosine to inosine editing#GO:0006382;RNA biosynthetic process#GO:0032774 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120848722|UniProtKB=A0ACM8F6B9 A0ACM8F6B9 LOC120848722 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121838030|UniProtKB=A0ACM8G799 A0ACM8G799 LOC121838030 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8037637|UniProtKB=A0ACM8DI74 A0ACM8DI74 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8030343|UniProtKB=A0ACM8DN84 A0ACM8DN84 Vamp7 PTHR21136:SF179 SNARE PROTEINS VESICLE-ASSOCIATED MEMBRANE PROTEIN 7 protein binding#GO:0005515;SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;SNARE binding#GO:0000149;molecular adaptor activity#GO:0060090;binding#GO:0005488 organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;endomembrane system organization#GO:0010256;protein localization to cell periphery#GO:1990778;metabolic process#GO:0008152;Golgi vesicle transport#GO:0048193;membrane invagination#GO:0010324;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;microtubule-based process#GO:0007017;vesicle organization#GO:0016050;exocytosis#GO:0006887;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;establishment of organelle localization#GO:0051656;endocytosis#GO:0006897;Golgi to plasma membrane protein transport#GO:0043001;export from cell#GO:0140352;lysosomal transport#GO:0007041;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;secretion by cell#GO:0032940;post-Golgi vesicle-mediated transport#GO:0006892;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;vesicle localization#GO:0051648;cytoskeleton-dependent intracellular transport#GO:0030705;membrane organization#GO:0061024;phagocytosis#GO:0006909;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;vesicle cytoskeletal trafficking#GO:0099518;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;protein localization to plasma membrane#GO:0072659;Golgi organization#GO:0007030;microtubule-based movement#GO:0007018;Golgi to plasma membrane transport#GO:0006893;catabolic process#GO:0009056;vesicle fusion#GO:0006906;organelle localization#GO:0051640;endosome to lysosome transport#GO:0008333;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;secretion#GO:0046903;localization#GO:0051179 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737 SNARE protein#PC00034;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121838057|UniProtKB=A0ACM8G6D6 A0ACM8G6D6 LOC121838057 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115325464|UniProtKB=A0ACM8F8H2 A0ACM8F8H2 LOC115325464 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034444|UniProtKB=A0ACM8EIH7 A0ACM8EIH7 RtcB PTHR11118:SF1 RNA-SPLICING LIGASE RTCB HOMOLOG RNA-SPLICING LIGASE RTCB catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8031929|UniProtKB=A0ACM8EEU8 A0ACM8EEU8 Sec3 PTHR16092:SF14 SEC3/SYNTAXIN-RELATED EXOCYST COMPLEX COMPONENT 1 phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 cellular process#GO:0009987;export from cell#GO:0140352;Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;Golgi vesicle transport#GO:0048193;transport#GO:0006810;secretion by cell#GO:0032940;vesicle-mediated transport to the plasma membrane#GO:0098876;post-Golgi vesicle-mediated transport#GO:0006892;exocytosis#GO:0006887;localization#GO:0051179;secretion#GO:0046903;cellular localization#GO:0051641;establishment of localization#GO:0051234 exocyst#GO:0000145;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150;SNARE protein#PC00034 IXOSC|EnsemblGenome=LOC121048145|UniProtKB=A0ACM8FHK1 A0ACM8FHK1 LOC121048145 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331376|UniProtKB=A0ACM8EC86 A0ACM8EC86 LOC115331376 PTHR33776:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025616|UniProtKB=A0ACM8EWS7 A0ACM8EWS7 Eps-15 PTHR11216:SF176 EH DOMAIN EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE CLONE 15, ISOFORM A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular localization#GO:0051641;localization#GO:0051179 intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;clathrin-coated pit#GO:0005905;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115329430|UniProtKB=A0ACM8F3B3 A0ACM8F3B3 LOC115329430 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8038785|UniProtKB=A0ACM8DK96 A0ACM8DK96 LOC8038785 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8034202|UniProtKB=A0ACM8E9H3 A0ACM8E9H3 RanBP3 PTHR23138:SF186 RAN BINDING PROTEIN RAN-BINDING PROTEIN 3-RELATED establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein export from nucleus#GO:0006611;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8031655|UniProtKB=A0ACM8E9X0 A0ACM8E9X0 mRRF1 PTHR20982:SF14 RIBOSOME RECYCLING FACTOR RIBOSOME-RECYCLING FACTOR, MITOCHONDRIAL protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;organelle organization#GO:0006996;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;translational termination#GO:0006415;translation#GO:0006412;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 translation release factor#PC00225 IXOSC|EnsemblGenome=LOC8042724|UniProtKB=A0ACM8DT10 A0ACM8DT10 LOC8042724 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330185|UniProtKB=A0ACM8EAF1 A0ACM8EAF1 LOC115330185 PTHR13168:SF0 ASSOCIATE OF C-MYC AMY-1 C-MYC-BINDING PROTEIN transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 PDGF signaling pathway#P00047>c-Myc#P01172 IXOSC|EnsemblGenome=LOC8033239|UniProtKB=A0ACM8EN82 A0ACM8EN82 LOC8033239 PTHR46498:SF1 GTP-BINDING PROTEIN 8 GTP-BINDING PROTEIN 8 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8026237|UniProtKB=A0ACM8ED54 A0ACM8ED54 LOC8026237 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319662|UniProtKB=A0ACM8EKJ9 A0ACM8EKJ9 LOC115319662 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036373|UniProtKB=A0ACM8DJZ7 A0ACM8DJZ7 Rpb5 PTHR10535:SF0 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on RNA#GO:0140098 tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;transcription by RNA polymerase I#GO:0006360;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;RNA polymerase I complex#GO:0005736;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 IXOSC|EnsemblGenome=LOC8030493|UniProtKB=A0ACM8DH74 A0ACM8DH74 Lis-1 PTHR44129:SF18 WD REPEAT-CONTAINING PROTEIN POP1 LISSENCEPHALY-1 HOMOLOG cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;axo-dendritic transport#GO:0008088;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;intracellular transport#GO:0046907;centrosome localization#GO:0051642;microtubule-based movement#GO:0007018;cellular localization#GO:0051641;localization#GO:0051179;retrograde axonal transport#GO:0008090;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;axonal transport#GO:0098930 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8042865|UniProtKB=A0ACM8FTW9 A0ACM8FTW9 LOC8042865 PTHR10519:SF46 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;signaling receptor complex#GO:0043235 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8040418|UniProtKB=A0ACM8DKK7 A0ACM8DKK7 LOC8040418 PTHR24341:SF6 HOMEOBOX PROTEIN ENGRAILED HOMEOBOX PROTEIN INVECTED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 Wnt signaling pathway#P00057>Wnt Target Genes#G01558 IXOSC|EnsemblGenome=LOC120843579|UniProtKB=A0ACM8EW80 A0ACM8EW80 LOC120843579 PTHR33147:SF39 DEFENSIN-LIKE PROTEIN 1 DEFENSIN-LIKE PROTEIN 98 response to stress#GO:0006950;response to stimulus#GO:0050896;defense response#GO:0006952 antimicrobial response protein#PC00051 IXOSC|EnsemblGenome=LOC115317576|UniProtKB=A0ACM8EHR4 A0ACM8EHR4 LOC115317576 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051878|UniProtKB=A0ACM8DLZ9 A0ACM8DLZ9 LOC8051878 PTHR23339:SF103 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE CYCLIN-DEPENDENT KINASE INHIBITOR 3 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC115326864|UniProtKB=A0ACM8EQX8 A0ACM8EQX8 LOC115326864 PTHR11177:SF144 CHITINASE CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8031203|UniProtKB=A0ACM8F195 A0ACM8F195 LOC8031203 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8027183|UniProtKB=A0ACM8DSE2 A0ACM8DSE2 LOC8027183 PTHR23049:SF71 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2 binding#GO:0005488;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120838512|UniProtKB=A0ACM8EKZ5 A0ACM8EKZ5 LOC120838512 PTHR10127:SF905 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8026880|UniProtKB=A0ACM8E9R7 A0ACM8E9R7 Ras85D PTHR24070:SF468 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-LIKE PROTEIN 1 hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 cell surface receptor signaling pathway#GO:0007166;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;cellular process#GO:0009987;ERBB signaling pathway#GO:0038127;epidermal growth factor receptor signaling pathway#GO:0007173;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;Ras protein signal transduction#GO:0007265;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of cell population proliferation#GO:0042127;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;intracellular signal transduction#GO:0035556;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GDP#P01291;PDGF signaling pathway#P00047>Ras#P01154;EGF receptor signaling pathway#P00018>Ras#P00552;Ras Pathway#P04393>Ras#P04547;Integrin signalling pathway#P00034>Ras#P00916;TGF-beta signaling pathway#P00052>Ras-GTP#P01280;VEGF signaling pathway#P00056>Ras#P01411;PI3 kinase pathway#P00048>Ras#P01182;Angiogenesis#P00005>Ras#P00238;p53 pathway feedback loops 2#P04398>Ras#P04651;FGF signaling pathway#P00021>Ras#P00633 IXOSC|EnsemblGenome=LOC120842116|UniProtKB=A0ACM8ET31 A0ACM8ET31 LOC120842116 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838560|UniProtKB=A0ACM8EK87 A0ACM8EK87 Tango11 PTHR16501:SF6 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 11 IXOSC|EnsemblGenome=LOC8034098|UniProtKB=A0ACM8DIW3 A0ACM8DIW3 Nt5a PTHR12103:SF38 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5'-NUCLEOTIDASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181;hydrolase#PC00121;nucleotide phosphatase#PC00173 IXOSC|EnsemblGenome=LOC8034328|UniProtKB=A0ACM8E9U2 A0ACM8E9U2 LOC8034328 PTHR11977:SF57 VILLIN VILLIN-LIKE PROTEIN QUAIL actin filament binding#GO:0051015;actin binding#GO:0003779;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;lipid binding#GO:0008289;protein-containing complex binding#GO:0044877;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981 regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of actin filament depolymerization#GO:0030834 actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC121835794|UniProtKB=A0ACM8FVU0 A0ACM8FVU0 LOC121835794 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115323464|UniProtKB=A0ACM8EF82 A0ACM8EF82 LOC115323464 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC8024654|UniProtKB=A0ACM8DIH0 A0ACM8DIH0 LOC8024654 PTHR24073:SF1234 DRAB5-RELATED RAB32, ISOFORM B ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;mitochondrion#GO:0005739;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802 G-protein#PC00020;small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8038367|UniProtKB=A0ACM8DK63 A0ACM8DK63 LOC8038367 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121836487|UniProtKB=A0ACM8G055 A0ACM8G055 LOC121836487 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC120836809|UniProtKB=A0ACM8EGT8 A0ACM8EGT8 LOC120836809 PTHR10352:SF88 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;eukaryotic translation initiation factor 3 complex#GO:0005852 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC121047095|UniProtKB=A0ACM8FE92 A0ACM8FE92 LOC121047095 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8036341|UniProtKB=A0ACM8ETN8 A0ACM8ETN8 LOC8036341 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 macromolecule localization#GO:0033036;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;lipid transport#GO:0006869;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;transport#GO:0006810;lipid metabolic process#GO:0006629;establishment of localization#GO:0051234;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;carbohydrate derivative catabolic process#GO:1901136;lipid localization#GO:0010876;localization#GO:0051179;ceramide metabolic process#GO:0006672 cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8040862|UniProtKB=A0ACM8DRG8 A0ACM8DRG8 LOC8040862 PTHR23345:SF15 VITELLOGENIN-RELATED VITELLOGENIN-6 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 storage protein#PC00210 IXOSC|EnsemblGenome=LOC120840472|UniProtKB=A0ACM8ENR7 A0ACM8ENR7 LOC120840472 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847834|UniProtKB=A0ACM8F4N0 A0ACM8F4N0 LOC120847834 PTHR10358:SF6 ENDOSULFINE ENDOSULFINE, ISOFORM A protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8051692|UniProtKB=A0ACM8E4V6 A0ACM8E4V6 LOC8051692 PTHR11915:SF422 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN ALPHA CHAIN, NON-ERYTHROCYTIC 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoskeleton#GO:0005856;cell junction#GO:0030054;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC120850396|UniProtKB=A0ACM8FLK8 A0ACM8FLK8 LOC120850396 PTHR12345:SF3 SYNTENIN RELATED SYNTENIN-1-LIKE PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115323617|UniProtKB=A0ACM8E4D6 A0ACM8E4D6 LOC115323617 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC8031956|UniProtKB=A0ACM8E8Y7 A0ACM8E8Y7 LOC8031956 PTHR24418:SF447 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRC64B catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;signaling receptor binding#GO:0005102;binding#GO:0005488 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940;Angiogenesis#P00005>Src#P00184 IXOSC|EnsemblGenome=LOC121834273|UniProtKB=A0ACM8DGT3 A0ACM8DGT3 PTHR11955:SF135 FATTY ACID BINDING PROTEIN FATTY ACID-BINDING PROTEIN, MUSCLE small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;organic acid binding#GO:0043177;fatty acid binding#GO:0005504;lipid binding#GO:0008289 monocarboxylic acid transport#GO:0015718;localization#GO:0051179;fatty acid transport#GO:0015908;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8042836|UniProtKB=A0ACM8FAC5 A0ACM8FAC5 PTHR23226:SF449 ZINC FINGER AND SCAN DOMAIN-CONTAINING FI21258P1 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121835141|UniProtKB=A0ACM8FSL7 A0ACM8FSL7 LOC121835141 PTHR31158:SF1 DUAL OXIDASE 2 DUAL OXIDASE MATURATION FACTOR 2 cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC115325614|UniProtKB=A0ACM8FQA0 A0ACM8FQA0 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8037295|UniProtKB=A0ACM8DUF5 A0ACM8DUF5 Brf PTHR11618:SF4 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 IXOSC|EnsemblGenome=LOC8036269|UniProtKB=A0ACM8G6V8 A0ACM8G6V8 LOC8036269 PTHR12317:SF0 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;biosynthetic process#GO:0009058;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid metabolic process#GO:0006638 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115324113|UniProtKB=A0ACM8FJC0 A0ACM8FJC0 LOC115324113 PTHR10075:SF131 BASIGIN RELATED INTERFERENCE HEDGEHOG cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8030631|UniProtKB=A0ACM8DS41 A0ACM8DS41 Cog2 PTHR12961:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 2 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 2 endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;COG complex#GO:0017119;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121833293|UniProtKB=A0ACM8FK87 A0ACM8FK87 LOC121833293 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839938|UniProtKB=A0ACM8FPI5 A0ACM8FPI5 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8027329|UniProtKB=A0ACM8F2C9 A0ACM8F2C9 LOC8027329 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8035019|UniProtKB=A0ACM8EFM2 A0ACM8EFM2 LOC8035019 PTHR11616:SF328 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;glycine transport#GO:0015816;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;import into cell#GO:0098657 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121837058|UniProtKB=A0ACM8G1U5 A0ACM8G1U5 LOC121837058 PTHR46481:SF13 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320881|UniProtKB=A0ACM8F5W5 A0ACM8F5W5 LOC115320881 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8038187|UniProtKB=A0ACM8DU83 A0ACM8DU83 LOC8038187 PTHR11748:SF111 D-LACTATE DEHYDROGENASE D-LACTATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8038245|UniProtKB=A0ACM8DGU0 A0ACM8DGU0 LOC8038245 PTHR22842:SF3 WD40 REPEAT PROTEIN WD REPEAT DOMAIN-CONTAINING PROTEIN 83 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8037993|UniProtKB=A0ACM8DIE4 A0ACM8DIE4 LOC8037993 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC8028713|UniProtKB=A0ACM8ECT0 A0ACM8ECT0 LOC8028713 PTHR21646:SF112 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 22 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of protein stability#GO:0031647;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8039189|UniProtKB=A0ACM8E129 A0ACM8E129 LOC8039189 PTHR33236:SF5 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030802|UniProtKB=A0ACM8DWT8 A0ACM8DWT8 LOC8030802 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8043792|UniProtKB=A0ACM8G0K8 A0ACM8G0K8 LOC8043792 PTHR11388:SF76 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 74D active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8039301|UniProtKB=A0ACM8G4Q0 A0ACM8G4Q0 LOC8039301 PTHR24238:SF83 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115330628|UniProtKB=A0ACM8ECF5 A0ACM8ECF5 LOC115330628 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042831|UniProtKB=A0ACM8E5X4 A0ACM8E5X4 LOC8042831 PTHR45938:SF14 ACP24A4-RELATED IXOLARIS IXOSC|EnsemblGenome=LOC121834007|UniProtKB=A0ACM8FPV5 A0ACM8FPV5 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832944|UniProtKB=A0ACM8G314 A0ACM8G314 LOC121832944 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121837608|UniProtKB=A0ACM8G5J6 A0ACM8G5J6 LOC121837608 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034992|UniProtKB=A0ACM8DJM2 A0ACM8DJM2 LOC8034992 PTHR21328:SF2 POLY ADP-RIBOSE POLYMERASE FAMILY, MEMBER PARP PROTEIN MONO-ADP-RIBOSYLTRANSFERASE PARP16 protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677;kinase binding#GO:0019900;binding#GO:0005488;kinase activator activity#GO:0019209;enzyme binding#GO:0019899 biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 nuclear envelope#GO:0005635;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum tubular network#GO:0071782;nucleus#GO:0005634;membrane#GO:0016020;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle envelope#GO:0031967;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 IXOSC|EnsemblGenome=LOC120838951|UniProtKB=A0ACM8EKC7 A0ACM8EKC7 LOC120838951 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024874|UniProtKB=A0ACM8E5V9 A0ACM8E5V9 Tbc1d22 PTHR22957:SF26 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN LD44506P molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme activator activity#GO:0008047 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8042834|UniProtKB=A0ACM8EE15 A0ACM8EE15 PTHR46512:SF1 PEPTIDYLPROLYL ISOMERASE PEPTIDYLPROLYL ISOMERASE macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;cytosol#GO:0005829;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120837577|UniProtKB=A0ACM8FKM3 A0ACM8FKM3 LOC120837577 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031567|UniProtKB=A0ACM8DIE8 A0ACM8DIE8 LOC8031567 PTHR11024:SF21 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER PROTEIN SEC13 HOMOLOG positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;membrane organization#GO:0061024;regulation of signal transduction#GO:0009966;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;positive regulation of cellular process#GO:0048522;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;vesicle budding from membrane#GO:0006900;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;protein localization to organelle#GO:0033365;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;localization#GO:0051179;nuclear transport#GO:0051169;positive regulation of TOR signaling#GO:0032008;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;COPII-coated vesicle budding#GO:0090114;nucleocytoplasmic transport#GO:0006913;vesicle-mediated transport#GO:0016192;organelle organization#GO:0006996;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;protein transport#GO:0015031;protein import into nucleus#GO:0006606;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;vesicle#GO:0031982;nuclear pore outer ring#GO:0031080;intracellular membrane-bounded organelle#GO:0043231;ER to Golgi transport vesicle membrane#GO:0012507;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;nucleus#GO:0005634;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;intracellular organelle#GO:0043229;coated membrane#GO:0048475;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;nuclear protein-containing complex#GO:0140513;bounding membrane of organelle#GO:0098588;nuclear pore#GO:0005643;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;vesicle coat#GO:0030120;nuclear envelope#GO:0005635;cytoplasm#GO:0005737 transporter#PC00227 IXOSC|EnsemblGenome=LOC115320759|UniProtKB=A0ACM8F3U3 A0ACM8F3U3 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121832962|UniProtKB=A0ACM8G1Z3 A0ACM8G1Z3 LOC121832962 PTHR11929:SF194 ALPHA- 1,3 -FUCOSYLTRANSFERASE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 3 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120843515|UniProtKB=A0ACM8EWB3 A0ACM8EWB3 LOC120843515 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC115321628|UniProtKB=A0ACM8FSH1 A0ACM8FSH1 LOC115321628 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8029078|UniProtKB=A0ACM8FDL1 A0ACM8FDL1 LOC8029078 PTHR11675:SF131 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 9-RELATED polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8052609|UniProtKB=A0ACM8E397 A0ACM8E397 PTHR23055:SF186 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG-LIKE PROTEIN calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC120836526|UniProtKB=A0ACM8EFV1 A0ACM8EFV1 PTHR46289:SF21 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837281|UniProtKB=A0ACM8G2N1 A0ACM8G2N1 LOC121837281 PTHR16516:SF4 AGAP007109-PA PR DOMAIN ZINC FINGER PROTEIN 8-LIKE regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121834826|UniProtKB=A0ACM8FRW6 A0ACM8FRW6 LOC121834826 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8038292|UniProtKB=A0ACM8FDG0 A0ACM8FDG0 LOC8038292 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8051849|UniProtKB=A0ACM8DTC5 A0ACM8DTC5 LOC8051849 PTHR32251:SF15 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE (DUF1295) cellular anatomical structure#GO:0110165;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC115309130|UniProtKB=A0ACM8DNC2 A0ACM8DNC2 LOC115309130 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120841036|UniProtKB=A0ACM8FTL5 A0ACM8FTL5 LOC120841036 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8028698|UniProtKB=A0ACM8FHG5 A0ACM8FHG5 LOC8028698 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120838918|UniProtKB=A0ACM8EK98 A0ACM8EK98 LOC120838918 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC115322256|UniProtKB=A0ACM8EKX5 A0ACM8EKX5 PTHR22768:SF0 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 DNA REPLICATION COMPLEX GINS PROTEIN PSF3 DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;DNA replication preinitiation complex#GO:0031261;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;GINS complex#GO:0000811 IXOSC|EnsemblGenome=LOC8038308|UniProtKB=A0ACM8F9S0 A0ACM8F9S0 LOC8038308 PTHR11792:SF17 ARRESTIN KURTZ ARRESTIN G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 receptor internalization#GO:0031623;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of response to stimulus#GO:0048583;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;nervous system process#GO:0050877;sensory perception#GO:0007600;localization#GO:0051179;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Wnt signaling pathway#P00057>beta-arrestin#P01456;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723 IXOSC|EnsemblGenome=LOC115319537|UniProtKB=A0ACM8F2B0 A0ACM8F2B0 LOC115319537 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120844722|UniProtKB=A0ACM8EZ25 A0ACM8EZ25 LOC120844722 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8029094|UniProtKB=A0ACM8FMQ8 A0ACM8FMQ8 PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8034059|UniProtKB=A0ACM8DIV1 A0ACM8DIV1 LOC8034059 PTHR45840:SF2 RHOMBOID-RELATED PROTEIN PROTEIN RHOMBOID-RELATED IXOSC|EnsemblGenome=LOC8039588|UniProtKB=A0ACM8EA50 A0ACM8EA50 PTHR11361:SF21 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 4 nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;organelle fission#GO:0048285;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;homologous recombination#GO:0035825;reproductive process#GO:0022414;DNA recombination#GO:0006310;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;cellular process#GO:0009987;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121838230|UniProtKB=A0ACM8G8J1 A0ACM8G8J1 LOC121838230 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115327734|UniProtKB=A0ACM8E8R6 A0ACM8E8R6 LOC115327734 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035533|UniProtKB=A0ACM8DUM7 A0ACM8DUM7 LOC8035533 PTHR11640:SF31 NEPHRIN MIP08606P binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115328135|UniProtKB=A0ACM8EZE0 A0ACM8EZE0 LOC115328135 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8053820|UniProtKB=A0ACM8F077 A0ACM8F077 PTHR45662:SF2 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITOL-3-PHOSPHATASE SAC1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;dephosphorylation#GO:0016311;lipid modification#GO:0030258;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121045916|UniProtKB=A0ACM8FCN0 A0ACM8FCN0 LOC121045916 PTHR24381:SF486 ZINC FINGER PROTEIN ADULT ENHANCER FACTOR 1-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8028043|UniProtKB=A0ACM8DJI5 A0ACM8DJI5 LOC8028043 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120844310|UniProtKB=A0ACM8EZG9 A0ACM8EZG9 LOC120844310 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120846124|UniProtKB=A0ACM8F0W8 A0ACM8F0W8 LOC120846124 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8040344|UniProtKB=A0ACM8DYF5 A0ACM8DYF5 LOC8040344 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179;transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8033281|UniProtKB=A0ACM8E7J5 A0ACM8E7J5 Dbp21E2 PTHR47960:SF1 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 RNA HELICASE binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8032264|UniProtKB=A0ACM8FG95 A0ACM8FG95 LOC8032264 PTHR24049:SF22 CRUMBS FAMILY MEMBER DELTA-LIKE PROTEIN cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609;establishment or maintenance of bipolar cell polarity#GO:0061245;cell adhesion#GO:0007155;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC121832952|UniProtKB=A0ACM8FV12 A0ACM8FV12 LOC121832952 PTHR23198:SF6 NUCLEOPORIN NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of nuclear pore#GO:0017056;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;chromosome localization#GO:0050000;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;protein import into nucleus#GO:0006606;protein transport#GO:0015031;cellular localization#GO:0051641;telomere tethering at nuclear periphery#GO:0034398;cellular component organization#GO:0016043;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;organelle localization#GO:0051640;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;nucleobase-containing compound transport#GO:0015931;telomere localization#GO:0034397 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC8053447|UniProtKB=A0ACM8DV02 A0ACM8DV02 PTHR24006:SF702 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 47 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC8038285|UniProtKB=A0ACM8E2X9 A0ACM8E2X9 LOC8038285 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120849823|UniProtKB=A0ACM8FL99 A0ACM8FL99 LOC120849823 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE-LIKE transferase#PC00220 IXOSC|EnsemblGenome=LOC8037284|UniProtKB=A0ACM8ETD3 A0ACM8ETD3 LOC8037284 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833000|UniProtKB=A0ACM8G4H1 A0ACM8G4H1 LOC121833000 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115332499|UniProtKB=A0ACM8EZ39 A0ACM8EZ39 LOC115332499 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115331844|UniProtKB=A0ACM8EDK1 A0ACM8EDK1 LOC115331844 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC115308493|UniProtKB=A0ACM8EXE5 A0ACM8EXE5 LOC115308493 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841320|UniProtKB=A0ACM8FJK4 A0ACM8FJK4 LOC120841320 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115319735|UniProtKB=A0ACM8EPC7 A0ACM8EPC7 LOC115319735 PTHR24394:SF67 ZINC FINGER PROTEIN MYONEURIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121046197|UniProtKB=A0ACM8FC92 A0ACM8FC92 LOC121046197 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121834230|UniProtKB=A0ACM8FPT7 A0ACM8FPT7 PTHR12317:SF0 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid metabolic process#GO:0006638 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115325720|UniProtKB=A0ACM8F6U3 A0ACM8F6U3 LOC115325720 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8042348|UniProtKB=A0ACM8E654 A0ACM8E654 LOC8042348 PTHR18966:SF602 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cellular process#GO:0009987;synaptic signaling#GO:0099536;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;regulation of trans-synaptic signaling#GO:0099177 postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC120838879|UniProtKB=A0ACM8FDV4 A0ACM8FDV4 LOC115308243 PTHR19957:SF307 SYNTAXIN SYNTAXIN-1A SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein transport#GO:0015031;secretion by cell#GO:0032940;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;cellular component organization#GO:0016043;export from cell#GO:0140352;vesicle fusion#GO:0006906;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;exocytosis#GO:0006887;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;membrane fusion#GO:0061025;organelle organization#GO:0006996;macromolecule localization#GO:0033036;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284 intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 SNARE protein#PC00034 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066 IXOSC|EnsemblGenome=LOC8040271|UniProtKB=A0ACM8EET1 A0ACM8EET1 SsRbeta PTHR12861:SF3 TRANSLOCON-ASSOCIATED PROTEIN, BETA SUBUNIT PRECURSOR TRAP-BETA SIGNAL SEQUENCE RECEPTOR BETA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT BETA membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115312708|UniProtKB=A0ACM8DSA3 A0ACM8DSA3 LOC115312708 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026137|UniProtKB=A0ACM8E153 A0ACM8E153 LOC8026137 PTHR24255:SF31 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED CUB DOMAIN-CONTAINING PROTEIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8032284|UniProtKB=A0ACM8EQ57 A0ACM8EQ57 LOC8032284 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120841190|UniProtKB=A0ACM8EQS4 A0ACM8EQS4 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043196|UniProtKB=A0ACM8G6N3 A0ACM8G6N3 Tmtc4 PTHR44227:SF3 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC4 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030 cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;protein O-linked glycosylation via mannose#GO:0035269;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;intracellular signal transduction#GO:0035556;protein metabolic process#GO:0019538;response to unfolded protein#GO:0006986;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;signal transduction#GO:0007165;carbohydrate derivative metabolic process#GO:1901135;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;glycoprotein biosynthetic process#GO:0009101;biological regulation#GO:0065007;biosynthetic process#GO:0009058 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8037119|UniProtKB=A0ACM8DPB2 A0ACM8DPB2 mRpL38 PTHR11362:SF133 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN LARGE RIBOSOMAL SUBUNIT PROTEIN ML38 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120837974|UniProtKB=A0ACM8EIP9 A0ACM8EIP9 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041106|UniProtKB=A0ACM8E938 A0ACM8E938 LOC8041106 PTHR12231:SF278 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN KAPPA, ISOFORM A protein binding#GO:0005515;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253;cell junction#GO:0030054 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8043724|UniProtKB=A0ACM8G1X4 A0ACM8G1X4 LOC8043724 PTHR44755:SF8 NATRIURETIC PEPTIDE RECEPTOR 3-RELATED RECEPTOR LIGAND BINDING REGION DOMAIN-CONTAINING PROTEIN binding#GO:0005488;hormone binding#GO:0042562;molecular transducer activity#GO:0060089;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8036869|UniProtKB=A0ACM8DMB9 A0ACM8DMB9 LOC8036869 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8029573|UniProtKB=A0ACM8F0B9 A0ACM8F0B9 PTHR46957:SF3 CYTOKINE RECEPTOR PROTEIN-TYROSINE-PHOSPHATASE transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115313914|UniProtKB=A0ACM8G0L8 A0ACM8G0L8 LOC115313914 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8053393|UniProtKB=A0ACM8FNS8 A0ACM8FNS8 PTHR16705:SF4 COMPLEXIN COMPLEXIN protein binding#GO:0005515;binding#GO:0005488;SNARE binding#GO:0000149 regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component organization#GO:0051128;regulation of signaling#GO:0023051;secretion by cell#GO:0032940;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;cellular process#GO:0009987;synaptic signaling#GO:0099536;neurotransmitter transport#GO:0006836;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;regulated exocytosis#GO:0045055;regulation of transport#GO:0051049;exocytosis#GO:0006887;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;localization#GO:0051179;cell communication#GO:0007154;secretion#GO:0046903;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234 neuron projection#GO:0043005;presynapse#GO:0098793;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;axon terminus#GO:0043679;cell junction#GO:0030054;membrane protein complex#GO:0098796;cell projection#GO:0042995;neuron projection terminus#GO:0044306;terminal bouton#GO:0043195;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;SNARE complex#GO:0031201;axon#GO:0030424;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8024624|UniProtKB=A0ACM8E7S4 A0ACM8E7S4 JTBR PTHR13041:SF3 JTB PROTEIN-RELATED PROTEIN JTB cytoskeleton-dependent cytokinesis#GO:0061640;mitotic cell cycle process#GO:1903047;cytokinesis#GO:0000910;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402 centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;midbody#GO:0030496;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115326027|UniProtKB=A0ACM8G0I1 A0ACM8G0I1 LOC115326027 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8050603|UniProtKB=A0ACM8E196 A0ACM8E196 LOC8050603 PTHR15036:SF96 PIKACHURIN-LIKE PROTEIN NEUREXIN-4 regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;developmental process#GO:0032502;multicellular organism development#GO:0007275 membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120848189|UniProtKB=A0ACM8F6C0 A0ACM8F6C0 LOC120848189 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842931|UniProtKB=A0ACM8EV06 A0ACM8EV06 LOC120842931 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316207|UniProtKB=A0ACM8EUG1 A0ACM8EUG1 LOC115316207 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8029231|UniProtKB=A0ACM8DWL1 A0ACM8DWL1 LOC8029231 PTHR14196:SF0 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 pattern specification process#GO:0007389;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8054007|UniProtKB=A0ACM8ERX6 A0ACM8ERX6 LOC8054007 PTHR19863:SF5 NEMITIN (NEURONAL ENRICHED MAP INTERACTING PROTEIN) HOMOLOG WD REPEAT-CONTAINING PROTEIN 47 IXOSC|EnsemblGenome=LOC121047535|UniProtKB=A0ACM8FGJ0 A0ACM8FGJ0 LOC121047535 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045489|UniProtKB=A0ACM8FHC0 A0ACM8FHC0 LOC121045489 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120844106|UniProtKB=A0ACM8FMU4 A0ACM8FMU4 LOC120844106 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;deaminase#PC00088;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120842102|UniProtKB=A0ACM8ET21 A0ACM8ET21 PTHR10545:SF29 DIAMINE N-ACETYLTRANSFERASE GH14572P-RELATED acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC115323836|UniProtKB=A0ACM8E3D7 A0ACM8E3D7 LOC115323836 PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 cytoskeleton organization#GO:0007010;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spindle#GO:0005819;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115316572|UniProtKB=A0ACM8EV17 A0ACM8EV17 LOC115316572 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8052877|UniProtKB=A0ACM8E894 A0ACM8E894 LOC8052877 PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 IXOSC|EnsemblGenome=LOC8028384|UniProtKB=A0ACM8FTZ8 A0ACM8FTZ8 LOC8028384 PTHR16206:SF4 DEP DOMAIN-CONTAINING PROTEIN LET-99 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120843834|UniProtKB=A0ACM8EWZ4 A0ACM8EWZ4 LOC120843834 PTHR10704:SF44 CARBOHYDRATE SULFOTRANSFERASE LD35051P-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 amino sugar metabolic process#GO:0006040;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115315998|UniProtKB=A0ACM8DVG6 A0ACM8DVG6 LOC115315998 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 IXOSC|EnsemblGenome=LOC121047483|UniProtKB=A0ACM8FG69 A0ACM8FG69 LOC121047483 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120843624|UniProtKB=A0ACM8EWK2 A0ACM8EWK2 LOC120843624 PTHR23049:SF71 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN 2 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;binding#GO:0005488 myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC120842718|UniProtKB=A0ACM8EUF9 A0ACM8EUF9 LOC120842718 PTHR46880:SF5 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835760|UniProtKB=A0ACM8FWG8 A0ACM8FWG8 LOC121835760 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8052457|UniProtKB=A0ACM8E8L4 A0ACM8E8L4 5PtaseI PTHR12997:SF2 TYPE I INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE INOSITOL POLYPHOSPHATE-5-PHOSPHATASE A catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181;hydrolase#PC00121 PI3 kinase pathway#P00048>SHIP#P01200 IXOSC|EnsemblGenome=LOC121836481|UniProtKB=A0ACM8FZS5 A0ACM8FZS5 LOC121836481 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035319|UniProtKB=A0ACM8DXC6 A0ACM8DXC6 LOC8035319 PTHR11176:SF62 BOULE-RELATED PROTEIN BOULE translation regulator activity#GO:0045182 positive regulation of biosynthetic process#GO:0009891;negative regulation of catabolic process#GO:0009895;positive regulation of translation#GO:0045727;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA stabilization#GO:0043489;regulation of biological quality#GO:0065008;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of translational initiation#GO:0006446;positive regulation of protein metabolic process#GO:0051247;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;mRNA stabilization#GO:0048255;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8030475|UniProtKB=A0ACM8E6T7 A0ACM8E6T7 LOC8030475 PTHR13145:SF0 SSM4 PROTEIN E3 UBIQUITIN-PROTEIN LIGASE MARCHF6 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8039750|UniProtKB=A0ACM8F8P2 A0ACM8F8P2 LOC8039750 PTHR15002:SF0 RIBOSOMAL BIOGENESIS PROTEIN LAS1L RIBOSOMAL BIOGENESIS PROTEIN LAS1L catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8035025|UniProtKB=A0ACM8F7T8 A0ACM8F7T8 LOC8035025 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115332996|UniProtKB=A0ACM8EDW6 A0ACM8EDW6 LOC115332996 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8032221|UniProtKB=A0ACM8G631 A0ACM8G631 LOC8032221 PTHR13192:SF3 MY011 PROTEIN COBALAMIN TRAFFICKING PROTEIN CBLD cellular process#GO:0009987;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC8034397|UniProtKB=A0ACM8E1Y3 A0ACM8E1Y3 wmd PTHR19877:SF13 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I SERINE-THREONINE KINASE RECEPTOR-ASSOCIATED PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SMN complex#GO:0032797;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;SMN-Sm protein complex#GO:0034719 translation factor#PC00223;translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8032723|UniProtKB=A0ACM8DX96 A0ACM8DX96 LOC8032723 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252 purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC8041401|UniProtKB=A0ACM8DKP2 A0ACM8DKP2 LOC8041401 PTHR24652:SF71 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 LOST AND FOUND, ISOFORM G IXOSC|EnsemblGenome=LOC8032963|UniProtKB=A0ACM8DHA2 A0ACM8DHA2 LOC8032963 PTHR22980:SF0 CORTISTATIN CENTROMERE PROTEIN S binding#GO:0005488;chromatin binding#GO:0003682 replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;resolution of meiotic recombination intermediates#GO:0000712;organelle organization#GO:0006996;meiotic nuclear division#GO:0140013;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;reproductive process#GO:0022414;homologous recombination#GO:0035825;DNA replication#GO:0006260;cell cycle process#GO:0022402;reciprocal homologous recombination#GO:0140527;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;meiosis I#GO:0007127;primary metabolic process#GO:0044238;cell cycle#GO:0007049;organelle fission#GO:0048285;DNA-templated DNA replication#GO:0006261;reciprocal meiotic recombination#GO:0007131;sexual reproduction#GO:0019953;nuclear division#GO:0000280;meiosis I cell cycle process#GO:0061982 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 peptide hormone#PC00179;neuropeptide#PC00162 IXOSC|EnsemblGenome=LOC8029871|UniProtKB=A0ACM8E8V8 A0ACM8E8V8 LOC8029871 PTHR44229:SF4 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] CHAIN DEHYDROGENASE_REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02990)-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034481|UniProtKB=A0ACM8EMC8 A0ACM8EMC8 LOC8034481 PTHR48075:SF1 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN LAMBDA-CRYSTALLIN HOMOLOG oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120847808|UniProtKB=A0ACM8F3V5 A0ACM8F3V5 LOC120847808 PTHR23199:SF12 NEUROTROPHIN 1-RELATED NEUROTROPHIN 1 IXOSC|EnsemblGenome=LOC115330582|UniProtKB=A0ACM8EUC0 A0ACM8EUC0 LOC115330582 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120836994|UniProtKB=A0ACM8G326 A0ACM8G326 LOC120836994 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120846476|UniProtKB=A0ACM8F256 A0ACM8F256 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121832974|UniProtKB=A0ACM8FT55 A0ACM8FT55 LOC121832974 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052416|UniProtKB=A0ACM8F9K3 A0ACM8F9K3 LOC8052416 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC120847203|UniProtKB=A0ACM8F3M9 A0ACM8F3M9 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030752|UniProtKB=A0ACM8E6V9 A0ACM8E6V9 LOC8030752 PTHR46001:SF3 TIAM (MAMMALIAN TUMOR INVASION AND METASTASIS FACTOR) HOMOLOG PROTEIN STILL LIFE, ISOFORM SIF TYPE 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8051510|UniProtKB=A0ACM8E994 A0ACM8E994 LOC8051510 PTHR23063:SF2 PHOSPHOLIPID ACYLTRANSFERASE GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 4, ISOFORM D-RELATED endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115316314|UniProtKB=A0ACM8DVU4 A0ACM8DVU4 LOC115316314 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8035816|UniProtKB=A0ACM8E970 A0ACM8E970 LOC8035816 PTHR46523:SF1 DCTP PYROPHOSPHATASE 1 DCTP PYROPHOSPHATASE 1 hydrolase activity#GO:0016787;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;macromolecule metabolic process#GO:0043170;nucleobase-containing small molecule metabolic process#GO:0055086;DNA metabolic process#GO:0006259;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;cellular response to stress#GO:0033554 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120840724|UniProtKB=A0ACM8EQ39 A0ACM8EQ39 LOC120840724 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8039949|UniProtKB=A0ACM8DYZ5 A0ACM8DYZ5 Stt3B PTHR13872:SF49 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT STT3B catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein N-linked glycosylation#GO:0006487;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8053557|UniProtKB=A0ACM8E9F8 A0ACM8E9F8 LOC8053557 PTHR23074:SF19 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A1 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;spindle#GO:0005819;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8030492|UniProtKB=A0ACM8DQX4 A0ACM8DQX4 LOC8030492 PTHR13393:SF0 SAM-DEPENDENT METHYLTRANSFERASE RNA N(6)-ADENOSINE-METHYLTRANSFERASE METTL16 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;post-transcriptional regulation of gene expression#GO:0010608;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;mRNA processing#GO:0006397;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836461|UniProtKB=A0ACM8FYA1 A0ACM8FYA1 LOC121836461 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8050670|UniProtKB=A0ACM8G2F3 A0ACM8G2F3 LOC8050670 PTHR47327:SF24 FI18240P1-RELATED RE15579P anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856 IXOSC|EnsemblGenome=LOC115314840|UniProtKB=A0ACM8EMB6 A0ACM8EMB6 LOC115314840 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8052998|UniProtKB=A0ACM8F2Q5 A0ACM8F2Q5 LOC8052998 PTHR12858:SF2 RIBOSOME BIOGENESIS PROTEIN RIBOSOME BIOGENESIS PROTEIN BMS1 HOMOLOG catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;GTPase activity#GO:0003924;RNA binding#GO:0003723;hydrolase activity#GO:0016787 maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;90S preribosome#GO:0030686;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120841337|UniProtKB=A0ACM8ERK6 A0ACM8ERK6 LOC120841337 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043486|UniProtKB=A0ACM8DL47 A0ACM8DL47 LOC8043486 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824 glutathione metabolic process#GO:0006749;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 isomerase#PC00135 IXOSC|EnsemblGenome=LOC120846800|UniProtKB=A0ACM8F3B0 A0ACM8F3B0 LOC120846800 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115329242|UniProtKB=A0ACM8FTX0 A0ACM8FTX0 LOC115329242 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8023236|UniProtKB=A0ACM8FCE8 A0ACM8FCE8 LOC8023236 PTHR14324:SF3 CONDENSIN-2 COMPLEX SUBUNIT H2 CONDENSIN-2 COMPLEX SUBUNIT H2 binding#GO:0005488;chromatin binding#GO:0003682 chromosome segregation#GO:0007059;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;chromosome separation#GO:0051304;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;sexual reproduction#GO:0019953;nuclear division#GO:0000280;chromosome condensation#GO:0030261;organelle fission#GO:0048285;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;reproductive process#GO:0022414;mitotic sister chromatid separation#GO:0051306;mitotic cell cycle#GO:0000278 chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;condensin complex#GO:0000796;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115331817|UniProtKB=A0ACM8G2D4 A0ACM8G2D4 LOC115331817 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115329792|UniProtKB=A0ACM8FKL4 A0ACM8FKL4 LOC115329792 PTHR11690:SF248 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC120845391|UniProtKB=A0ACM8F0L0 A0ACM8F0L0 LOC120845391 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051419|UniProtKB=A0ACM8EXK7 A0ACM8EXK7 LOC8051419 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC115327094|UniProtKB=A0ACM8E830 A0ACM8E830 LOC115327094 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041761|UniProtKB=A0ACM8F570 A0ACM8F570 LOC8041761 PTHR34339:SF2 STIMULATOR OF INTERFERON GENES PROTEIN STIMULATOR OF INTERFERON GENES PROTEIN HOMOLOG guanyl nucleotide binding#GO:0019001;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 vacuole organization#GO:0007033;organelle assembly#GO:0070925;response to external biotic stimulus#GO:0043207;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;response to external stimulus#GO:0009605;defense response#GO:0006952;regulation of catabolic process#GO:0009894;innate immune response#GO:0045087;positive regulation of catabolic process#GO:0009896;biological regulation#GO:0065007;response to other organism#GO:0051707;macroautophagy#GO:0016236;positive regulation of cellular process#GO:0048522;immune response#GO:0006955;regulation of metabolic process#GO:0019222;reticulophagy#GO:0061709;process utilizing autophagic mechanism#GO:0061919;positive regulation of metabolic process#GO:0009893;immune system process#GO:0002376;positive regulation of macroautophagy#GO:0016239;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of macroautophagy#GO:0016241;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;cellular component assembly#GO:0022607;defense response to other organism#GO:0098542;positive regulation of biological process#GO:0048518;defense response to symbiont#GO:0140546;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to biotic stimulus#GO:0009607;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950 organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 IXOSC|EnsemblGenome=LOC115309242|UniProtKB=A0ACM8DNJ9 A0ACM8DNJ9 LOC115309242 PTHR22968:SF24 PROTEIN KINASE C, MU SERINE_THREONINE-PROTEIN KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Angiogenesis#P00005>PKC#P00219;VEGF signaling pathway#P00056>PKC#P01425;EGF receptor signaling pathway#P00018>PKC#P00565 IXOSC|EnsemblGenome=LOC8037797|UniProtKB=A0ACM8DI93 A0ACM8DI93 LOC8037797 PTHR12649:SF11 PEPTIDYL-TRNA HYDROLASE 2 PEPTIDYL-TRNA HYDROLASE 2-RELATED IXOSC|EnsemblGenome=LOC120839767|UniProtKB=A0ACM8F636 A0ACM8F636 LOC120839767 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121834162|UniProtKB=A0ACM8FMZ4 A0ACM8FMZ4 LOC121834162 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8041781|UniProtKB=A0ACM8E9P8 A0ACM8E9P8 Rbcn-3B PTHR44099:SF4 RABCONNECTIN-3B, ISOFORM A RABCONNECTIN-3B, ISOFORM A intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121833087|UniProtKB=A0ACM8FKB6 A0ACM8FKB6 LOC121833087 PTHR45766:SF6 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER SNF2 RELATED CHROMATIN REMODELING ANNEALING HELICASE 1 nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677 replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 IXOSC|EnsemblGenome=LOC115309264|UniProtKB=A0ACM8DNF6 A0ACM8DNF6 LOC115309264 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115324861|UniProtKB=A0ACM8FSQ7 A0ACM8FSQ7 LOC115324861 PTHR21190:SF1 GH10077P GH10077P IXOSC|EnsemblGenome=LOC8024587|UniProtKB=A0ACM8G272 A0ACM8G272 LOC8024587 PTHR10373:SF38 TRANSCRIPTION FACTOR 7 FAMILY MEMBER PROTEIN PANGOLIN, ISOFORM J sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 chromosome#GO:0005694;RNA polymerase II transcription regulator complex#GO:0090575;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8028868|UniProtKB=A0ACM8DNC7 A0ACM8DNC7 LOC8028868 PTHR12706:SF30 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH-RELATED IXOSC|EnsemblGenome=LOC120844512|UniProtKB=A0ACM8EYT7 A0ACM8EYT7 LOC120844512 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8031119|UniProtKB=A0ACM8DUX5 A0ACM8DUX5 LOC8031119 PTHR11969:SF99 MAX DIMERIZATION, MAD MAX-BINDING PROTEIN MNT DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8051161|UniProtKB=A0ACM8F5Y4 A0ACM8F5Y4 LOC8051161 PTHR11069:SF23 GLUCOSYLCERAMIDASE LYSOSOMAL ACID GLUCOSYLCERAMIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;carbohydrate derivative catabolic process#GO:1901136 IXOSC|EnsemblGenome=LOC120846321|UniProtKB=A0ACM8F2Z4 A0ACM8F2Z4 LOC120846321 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115331857|UniProtKB=A0ACM8EDK7 A0ACM8EDK7 LOC115331857 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850706|UniProtKB=A0ACM8FAW0 A0ACM8FAW0 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120846594|UniProtKB=A0ACM8F1Z3 A0ACM8F1Z3 LOC120846594 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cell adhesion#GO:0007155;developmental process#GO:0032502;post-embryonic development#GO:0009791;animal gross anatomical part developmental process#GO:0160108;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;circulatory system development#GO:0072359;heart development#GO:0007507;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8035838|UniProtKB=A0ACM8DJV6 A0ACM8DJV6 LOC8035838 PTHR18945:SF916 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA-2 signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;neurotransmitter receptor activity#GO:0030594;chloride channel activity#GO:0005254;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;synaptic signaling#GO:0099536;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 signaling receptor complex#GO:0043235;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;synapse#GO:0045202;cellular anatomical structure#GO:0110165;GABA-ergic synapse#GO:0098982;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8037670|UniProtKB=A0ACM8DM75 A0ACM8DM75 BRWD3 PTHR16266:SF17 WD REPEAT DOMAIN 9 BRWD3 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120837733|UniProtKB=A0ACM8EHN4 A0ACM8EHN4 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8025720|UniProtKB=A0ACM8E168 A0ACM8E168 LOC8025720 PTHR11548:SF2 THYMIDYLATE SYNTHASE 1 THYMIDYLATE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;nucleoside monophosphate biosynthetic process#GO:0009124;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 Formyltetrahydrofolate biosynthesis#P02743>Thymidylate synthase#P02954;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>Thymidylate synthase#P02913;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957 IXOSC|EnsemblGenome=LOC121046368|UniProtKB=A0ACM8FCL6 A0ACM8FCL6 LOC121046368 PTHR45828:SF9 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE ABNORMAL CELL MIGRATION PROTEIN 18-LIKE FIBRONECTIN TYPE I DOMAIN-CONTAINING PROTEIN-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC120841253|UniProtKB=A0ACM8ES98 A0ACM8ES98 LOC120841253 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC8035648|UniProtKB=A0ACM8ENF7 A0ACM8ENF7 Sin3A PTHR12346:SF71 SIN3B-RELATED PAIRED AMPHIPATHIC HELIX PROTEIN SIN3A transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 Huntington disease#P00029>Sin3A#P00771 IXOSC|EnsemblGenome=LOC120840430|UniProtKB=A0ACM8EPH2 A0ACM8EPH2 LOC120840430 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8043039|UniProtKB=A0ACM8EZF7 A0ACM8EZF7 LOC8043039 PTHR11640:SF172 NEPHRIN NEPHRIN-LIKE binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115311464|UniProtKB=A0ACM8FQE6 A0ACM8FQE6 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8026787|UniProtKB=A0ACM8FHB1 A0ACM8FHB1 LOC8026787 PTHR10760:SF18 TORSIN LD13476P-RELATED response to misfolded protein#GO:0051788;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;cellular response to stress#GO:0033554;cellular response to misfolded protein#GO:0071218;cellular response to topologically incorrect protein#GO:0035967 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 IXOSC|EnsemblGenome=LOC121837496|UniProtKB=A0ACM8G506 A0ACM8G506 LOC121837496 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8037556|UniProtKB=A0ACM8DTH9 A0ACM8DTH9 LOC8037556 PTHR17039:SF0 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN MPP10 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8035749|UniProtKB=A0ACM8FPT2 A0ACM8FPT2 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120851142|UniProtKB=A0ACM8FA57 A0ACM8FA57 LOC120851142 PTHR10075:SF130 BASIGIN RELATED NEURAL CELL ADHESION MOLECULE L1 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8034129|UniProtKB=A0ACM8DJ04 A0ACM8DJ04 LOC8034129 PTHR21252:SF3 TB1 PROTEIN-RELATED FI08023P-RELATED mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;mitochondrial fission#GO:0000266;organelle fission#GO:0048285;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 IXOSC|EnsemblGenome=LOC121833541|UniProtKB=A0ACM8FMK4 A0ACM8FMK4 LOC121833541 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8051410|UniProtKB=A0ACM8DRY6 A0ACM8DRY6 LOC8051410 PTHR10263:SF18 V-TYPE PROTON ATPASE PROTEOLIPID SUBUNIT V-TYPE PROTON ATPASE 21 KDA PROTEOLIPID SUBUNIT C'' membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC8042487|UniProtKB=A0ACM8EHL1 A0ACM8EHL1 LOC8042487 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;steroid hydroxylase activity#GO:0008395;binding#GO:0005488;tetrapyrrole binding#GO:0046906 metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;steroid metabolic process#GO:0008202 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115330592|UniProtKB=A0ACM8EVS1 A0ACM8EVS1 LOC115330592 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120847642|UniProtKB=A0ACM8F4A4 A0ACM8F4A4 LOC120847642 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC115313190|UniProtKB=A0ACM8EI91 A0ACM8EI91 LOC115313190 PTHR31198:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 84 CENTROSOMAL AT-AC SPLICING FACTOR IXOSC|EnsemblGenome=LOC115328197|UniProtKB=A0ACM8ENP3 A0ACM8ENP3 LOC115328197 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120837881|UniProtKB=A0ACM8DJE5 A0ACM8DJE5 LOC120837881 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8053189|UniProtKB=A0ACM8FU11 A0ACM8FU11 LOC8053189 PTHR20661:SF0 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS W PROTEIN GLUCOSAMINYL-PHOSPHATIDYLINOSITOL-ACYLTRANSFERASE PIGW acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8035126|UniProtKB=A0ACM8DV10 A0ACM8DV10 LOC8035126 PTHR14024:SF49 PERILIPIN LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 1 regulation of localization#GO:0032879;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;lipid storage#GO:0019915;cellular process#GO:0009987;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytosol#GO:0005829;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053678|UniProtKB=A0ACM8DLX1 A0ACM8DLX1 Ctu2 PTHR20882:SF14 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 2 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA wobble position uridine thiolation#GO:0002143;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;tRNA thio-modification#GO:0034227;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC121046102|UniProtKB=A0ACM8FXU6 A0ACM8FXU6 LOC121046102 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836036|UniProtKB=A0ACM8F2N8 A0ACM8F2N8 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;localization within membrane#GO:0051668;organelle localization#GO:0051640;localization#GO:0051179;negative regulation of macromolecule metabolic process#GO:0010605;protein localization to nucleus#GO:0034504;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule localization#GO:0033036;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;membrane organization#GO:0061024;biological regulation#GO:0065007;transport#GO:0006810;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;establishment of organelle localization#GO:0051656;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC115328740|UniProtKB=A0ACM8FKC0 A0ACM8FKC0 LOC115328740 PTHR11407:SF63 LYSOZYME C LYSOZYME hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;lysozyme activity#GO:0003796;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC121047794|UniProtKB=A0ACM8FHT2 A0ACM8FHT2 LOC121047794 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843677|UniProtKB=A0ACM8EWQ6 A0ACM8EWQ6 LOC120843677 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032298|UniProtKB=A0ACM8G0K4 A0ACM8G0K4 LOC8032298 PTHR13555:SF36 C2H2 ZINC FINGER CGI-62-RELATED ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1B C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8042089|UniProtKB=A0ACM8F9S2 A0ACM8F9S2 Sin1 PTHR13335:SF1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT MAPKAP1 phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;TORC2 signaling#GO:0038203;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;TOR signaling#GO:0031929;signaling#GO:0023052;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;TOR complex#GO:0038201;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120835953|UniProtKB=A0ACM8F2S6 A0ACM8F2S6 AlaRS PTHR11777:SF9 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;deacylase activity#GO:0160215;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689 protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC120839825|UniProtKB=A0ACM8ENS3 A0ACM8ENS3 LOC120839825 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031915|UniProtKB=A0ACM8E993 A0ACM8E993 LOC8031915 PTHR22882:SF3 SYNPHILIN-1 SYNPHILIN-1 protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;enzyme binding#GO:0019899 Parkinson disease#P00049>Synphilin#P01225 IXOSC|EnsemblGenome=LOC115314672|UniProtKB=A0ACM8G2X3 A0ACM8G2X3 LOC115314672 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120845990|UniProtKB=A0ACM8F0Z0 A0ACM8F0Z0 LOC120845990 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120848989|UniProtKB=A0ACM8F7Q5 A0ACM8F7Q5 LOC120848989 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318718|UniProtKB=A0ACM8FWC3 A0ACM8FWC3 LOC115318718 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC121835624|UniProtKB=A0ACM8FV78 A0ACM8FV78 LOC121835624 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029621|UniProtKB=A0ACM8ECM5 A0ACM8ECM5 LOC8029621 PTHR44414:SF1 PROTEIN NEDD1 PROTEIN NEDD1 tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;mitotic cell cycle#GO:0000278 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929 IXOSC|EnsemblGenome=LOC121835234|UniProtKB=A0ACM8FS29 A0ACM8FS29 LOC121835234 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8032740|UniProtKB=A0ACM8FV59 A0ACM8FV59 LOC8032740 PTHR22963:SF39 ENDOGLIN-RELATED DUMPY, ISOFORM Q IXOSC|EnsemblGenome=LOC8041651|UniProtKB=A0ACM8E8W6 A0ACM8E8W6 LOC8041651 PTHR19868:SF0 RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1 SMALL RIBOSOMAL SUBUNIT PROTEIN RACK1 protein binding#GO:0005515;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;kinase binding#GO:0019900;binding#GO:0005488;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 metabolic process#GO:0008152;translational elongation#GO:0006414;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;gene expression#GO:0010467;negative regulation of translation#GO:0017148;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;rescue of stalled cytosolic ribosome#GO:0072344;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;translation#GO:0006412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120850635|UniProtKB=A0ACM8FBB1 A0ACM8FBB1 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC115316414|UniProtKB=A0ACM8DVW2 A0ACM8DVW2 LOC115316414 PTHR33147:SF39 DEFENSIN-LIKE PROTEIN 1 DEFENSIN-LIKE PROTEIN 98 defense response#GO:0006952;response to stimulus#GO:0050896;response to stress#GO:0006950 antimicrobial response protein#PC00051 IXOSC|EnsemblGenome=LOC120849884|UniProtKB=A0ACM8G921 A0ACM8G921 LOC120849884 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835009|UniProtKB=A0ACM8FRY0 A0ACM8FRY0 LOC121835009 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8036358|UniProtKB=A0ACM8DHD6 A0ACM8DHD6 LOC8036358 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8037429|UniProtKB=A0ACM8DI30 A0ACM8DI30 LOC8037429 PTHR23104:SF17 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8051433|UniProtKB=A0ACM8DSD4 A0ACM8DSD4 Usp20-33 PTHR21646:SF86 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;regulation of protein stability#GO:0031647;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of biological quality#GO:0065008;anatomical structure development#GO:0048856;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC120836788|UniProtKB=A0ACM8G002 A0ACM8G002 LOC120836788 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8031438|UniProtKB=A0ACM8E6S6 A0ACM8E6S6 LOC8031438 PTHR21245:SF15 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 46-LIKE PROTEIN RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8026746|UniProtKB=A0ACM8FU46 A0ACM8FU46 LOC8026746 PTHR45630:SF23 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE polyamine transmembrane transporter activity#GO:0015203;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;nitrogen compound transport#GO:0071705;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;transmembrane transport#GO:0055085;localization#GO:0051179;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120838262|UniProtKB=A0ACM8EJI5 A0ACM8EJI5 glu PTHR18937:SF172 STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN organelle fission#GO:0048285;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;chromosome segregation#GO:0007059;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987 chromosome#GO:0005694;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;condensin complex#GO:0000796;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8027199|UniProtKB=A0ACM8ETM9 A0ACM8ETM9 LOC8027199 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC121048340|UniProtKB=A0ACM8FI76 A0ACM8FI76 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028758|UniProtKB=A0ACM8EHF8 A0ACM8EHF8 LOC8028758 PTHR15934:SF2 RNA 2',3'-CYCLIC PHOSPHODIESTERASE A-KINASE ANCHOR PROTEIN 7-LIKE PHOSPHOESTERASE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;protein kinase A binding#GO:0051018;protein kinase A regulatory subunit binding#GO:0034237;protein binding#GO:0005515 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120841263|UniProtKB=A0ACM8EQX0 A0ACM8EQX0 LOC120841263 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327112|UniProtKB=A0ACM8FUN7 A0ACM8FUN7 LOC115327112 PTHR36694:SF14 PASIFLORA 1, ISOFORM A-RELATED LP21121P IXOSC|EnsemblGenome=LOC8051315|UniProtKB=A0ACM8G8C9 A0ACM8G8C9 LOC8051315 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115315020|UniProtKB=A0ACM8DUX4 A0ACM8DUX4 LOC115315020 PTHR24228:SF59 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR NEUROPEPTIDE RECEPTOR 15 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120840788|UniProtKB=A0ACM8ER65 A0ACM8ER65 LOC120840788 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC121835840|UniProtKB=A0ACM8FWT3 A0ACM8FWT3 LOC121835840 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8025915|UniProtKB=A0ACM8FLJ2 A0ACM8FLJ2 HUWE1 PTHR11254:SF445 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE HECT-TYPE E3 UBIQUITIN TRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E3#P01490 IXOSC|EnsemblGenome=LOC8024493|UniProtKB=A0ACM8EAQ6 A0ACM8EAQ6 LOC8024493 PTHR19918:SF1 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED FIZZY-RELATED PROTEIN HOMOLOG protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;binding#GO:0005488;enzyme activator activity#GO:0008047 positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;proteasomal protein catabolic process#GO:0010498;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of metabolic process#GO:0009893;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;primary metabolic process#GO:0044238;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8034104|UniProtKB=A0ACM8DMS9 A0ACM8DMS9 Hlc PTHR47959:SF21 ATP-DEPENDENT RNA HELICASE RHLE-RELATED ATP-DEPENDENT RNA HELICASE DDX56-RELATED RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8035017|UniProtKB=A0ACM8ESY6 A0ACM8ESY6 Crk PTHR19969:SF5 SH2-SH3 ADAPTOR PROTEIN-RELATED ADAPTER MOLECULE CRK receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;protein tyrosine kinase binding#GO:1990782;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;cell migration#GO:0016477;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Crk#P00207 IXOSC|EnsemblGenome=LOC120836023|UniProtKB=A0ACM8F6E4 A0ACM8F6E4 LOC120836023 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843388|UniProtKB=A0ACM8G955 A0ACM8G955 LOC120843388 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115312113|UniProtKB=A0ACM8FWB0 A0ACM8FWB0 LOC115312113 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8037124|UniProtKB=A0ACM8DPA0 A0ACM8DPA0 LOC8037124 PTHR12403:SF11 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-LIKE PROTEIN transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;TRAPPII protein complex#GO:1990071;vesicle#GO:0031982;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;TRAPP complex#GO:0030008;cytoplasm#GO:0005737 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8028586|UniProtKB=A0ACM8DZJ3 A0ACM8DZJ3 LOC8028586 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8035469|UniProtKB=A0ACM8EUS3 A0ACM8EUS3 PTHR19282:SF570 TETRASPANIN TETRASPANIN TSPA-RELATED scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115322471|UniProtKB=A0ACM8ER92 A0ACM8ER92 LOC115322471 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120847479|UniProtKB=A0ACM8F3A2 A0ACM8F3A2 sfl PTHR10605:SF77 HEPARAN SULFATE SULFOTRANSFERASE BIFUNCTIONAL HEPARAN SULFATE N-DEACETYLASE_N-SULFOTRANSFERASE transferase activity#GO:0016740;deacylase activity#GO:0160215;catalytic activity#GO:0003824;deacetylase activity#GO:0019213;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8039931|UniProtKB=A0ACM8EZZ6 A0ACM8EZZ6 LOC8039931 PTHR23301:SF107 CHITIN BINDING PERITROPHIN-A LD20793P carbohydrate derivative binding#GO:0097367;binding#GO:0005488 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8027497|UniProtKB=A0ACM8F8Z5 A0ACM8F8Z5 LOC8027497 PTHR12618:SF20 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 PHD AND RING FINGER DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8034244|UniProtKB=A0ACM8DST2 A0ACM8DST2 PTHR13976:SF25 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED RNA-BINDING PROTEIN FUSILLI binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC121048214|UniProtKB=A0ACM8FHU8 A0ACM8FHU8 LOC121048214 PTHR21258:SF62 DOCKING PROTEIN RELATED DOWNSTREAM OF KINASE signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121047746|UniProtKB=A0ACM8FFD4 A0ACM8FFD4 LOC121047746 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120850204|UniProtKB=A0ACM8F8B8 A0ACM8F8B8 LOC120850204 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325609|UniProtKB=A0ACM8EWG4 A0ACM8EWG4 LOC115325609 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115333082|UniProtKB=A0ACM8EEC5 A0ACM8EEC5 LOC115333082 PTHR12019:SF9 LAMINA-ASSOCIATED POLYPEPTIDE THYMOPOIETIN THYMOPOIETIN peptide hormone#PC00179;intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8029067|UniProtKB=A0ACM8EDY3 A0ACM8EDY3 LOC8029067 PTHR24171:SF15 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50-RELATED IXOSC|EnsemblGenome=LOC120838536|UniProtKB=A0ACM8EL21 A0ACM8EL21 LOC120838536 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030415|UniProtKB=A0ACM8DY08 A0ACM8DY08 LOC8030415 PTHR13237:SF9 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED NEUROGUIDIN gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8031001|UniProtKB=A0ACM8F9X5 A0ACM8F9X5 LOC8031001 PTHR48103:SF2 MIDASIN-RELATED MIDASIN pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;ribosomal large subunit assembly#GO:0000027;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120847559|UniProtKB=A0ACM8F449 A0ACM8F449 LOC120847559 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121836476|UniProtKB=A0ACM8FYC0 A0ACM8FYC0 LOC121836476 PTHR24264:SF91 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120846488|UniProtKB=A0ACM8F3B9 A0ACM8F3B9 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841378|UniProtKB=A0ACM8G8H1 A0ACM8G8H1 LOC120841378 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835226|UniProtKB=A0ACM8FTY4 A0ACM8FTY4 LOC121835226 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220 IXOSC|EnsemblGenome=LOC8042799|UniProtKB=A0ACM8DL05 A0ACM8DL05 Cda4 PTHR45985:SF3 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 4 IXOSC|EnsemblGenome=LOC8027276|UniProtKB=A0ACM8EBW4 A0ACM8EBW4 LOC8027276 PTHR43607:SF10 V-TYPE PROTON ATPASE CATALYTIC SUBUNIT A H(+)-TRANSPORTING TWO-SECTOR ATPASE monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;lysosome#GO:0005764;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;lytic vacuole membrane#GO:0098852;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC115315804|UniProtKB=A0ACM8DVP1 A0ACM8DVP1 LOC115315804 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046836|UniProtKB=A0ACM8FF47 A0ACM8FF47 LOC121046836 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841657|UniProtKB=A0ACM8ERR3 A0ACM8ERR3 LOC120841657 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031975|UniProtKB=A0ACM8DWB8 A0ACM8DWB8 LOC8031975 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8032760|UniProtKB=A0ACM8DGS5 A0ACM8DGS5 LOC8032760 PTHR10736:SF70 BESTROPHIN BESTROPHIN HOMOLOG monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC121834792|UniProtKB=A0ACM8FQ04 A0ACM8FQ04 LOC121834792 PTHR13303:SF0 PREFOLDIN SUBUNIT 2 PREFOLDIN SUBUNIT 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467 protein-containing complex#GO:0032991 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8025394|UniProtKB=A0ACM8G2K9 A0ACM8G2K9 CaMKII PTHR24347:SF458 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE II ALPHA CHAIN catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;calcium/calmodulin-dependent protein kinase activity#GO:0004683;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674 regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of localization#GO:0032879;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847;Ionotropic glutamate receptor pathway#P00037>CaMKII#P01023 IXOSC|EnsemblGenome=LOC121837082|UniProtKB=A0ACM8G1N3 A0ACM8G1N3 LOC121837082 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846305|UniProtKB=A0ACM8F199 A0ACM8F199 LOC120846305 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC121837958|UniProtKB=A0ACM8G5Z2 A0ACM8G5Z2 LOC121837958 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837864|UniProtKB=A0ACM8G5H2 A0ACM8G5H2 LOC121837864 PTHR14920:SF0 OSMOTIC AVOIDANCE ABNORMAL PROTEIN 1/WD REPEAT MEMBRANE PROTEIN WD REPEAT DOMAIN 19 plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;intraciliary transport#GO:0042073;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intraciliary transport particle A#GO:0030991;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intraciliary transport particle#GO:0030990 IXOSC|EnsemblGenome=LOC120839611|UniProtKB=A0ACM8EM39 A0ACM8EM39 LOC120839611 PTHR23235:SF130 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 367 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120847724|UniProtKB=A0ACM8F5I6 A0ACM8F5I6 LOC120847724 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120846567|UniProtKB=A0ACM8F3K0 A0ACM8F3K0 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 endomembrane system organization#GO:0010256;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;cellular localization#GO:0051641;negative regulation of biosynthetic process#GO:0009890;membrane organization#GO:0061024;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;intracellular protein localization#GO:0008104;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;transport#GO:0006810;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640 intracellular organelle#GO:0043229;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC121836988|UniProtKB=A0ACM8G2G3 A0ACM8G2G3 LOC121836988 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8028472|UniProtKB=A0ACM8DRL4 A0ACM8DRL4 LOC8028472 PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC121838033|UniProtKB=A0ACM8G5X2 A0ACM8G5X2 LOC121838033 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8038113|UniProtKB=A0ACM8EIL4 A0ACM8EIL4 Col4a1 PTHR24023:SF1137 COLLAGEN ALPHA COLLAGEN ALPHA-1(IV) CHAIN-RELATED structural molecule activity#GO:0005198;extracellular matrix structural constituent#GO:0005201 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Collagen#P00922 IXOSC|EnsemblGenome=LOC8030903|UniProtKB=A0ACM8FAA8 A0ACM8FAA8 Mkp3 PTHR10159:SF541 DUAL SPECIFICITY PROTEIN PHOSPHATASE DUAL SPECIFICITY PROTEIN PHOSPHATASE MPK3 protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 IXOSC|EnsemblGenome=LOC115320670|UniProtKB=A0ACM8E0G4 A0ACM8E0G4 LOC115320670 PTHR24243:SF237 G-PROTEIN COUPLED RECEPTOR PYROKININ-1 RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115309679|UniProtKB=A0ACM8F1A3 A0ACM8F1A3 LOC115309679 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115324160|UniProtKB=A0ACM8FCB2 A0ACM8FCB2 LOC115324160 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837297|UniProtKB=A0ACM8G4F6 A0ACM8G4F6 LOC121837297 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838812|UniProtKB=A0ACM8EK02 A0ACM8EK02 LOC120838812 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832894|UniProtKB=A0ACM8FQ48 A0ACM8FQ48 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115314824|UniProtKB=A0ACM8DUI5 A0ACM8DUI5 LOC115314824 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC115308291|UniProtKB=A0ACM8FA05 A0ACM8FA05 LOC115308291 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024633|UniProtKB=A0ACM8DIF9 A0ACM8DIF9 LOC8024633 PTHR18929:SF132 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;isomerase activity#GO:0016853 protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;response to stimulus#GO:0050896;macromolecule biosynthetic process#GO:0009059;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8038096|UniProtKB=A0ACM8DN60 A0ACM8DN60 LOC8038096 PTHR11932:SF174 CULLIN CULLIN-2 enzyme binding#GO:0019899;protein complex scaffold activity#GO:0140378;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;structural molecule activity#GO:0005198;protein binding#GO:0005515 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056 cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8040304|UniProtKB=A0ACM8FJA4 A0ACM8FJA4 nonC PTHR11139:SF71 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED SERINE_THREONINE-PROTEIN KINASE SMG1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular response to stress#GO:0033554;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;response to stress#GO:0006950;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120839826|UniProtKB=A0ACM8FUL0 A0ACM8FUL0 LOC120839826 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8040955|UniProtKB=A0ACM8DGM7 A0ACM8DGM7 Arpc2 PTHR12058:SF0 ARP2/3 COMPLEX 34 KDA SUBUNIT ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;actin filament polymerization#GO:0030041;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;supramolecular fiber organization#GO:0097435;cortical actin cytoskeleton organization#GO:0030866;actin polymerization or depolymerization#GO:0008154;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin filament organization#GO:0007015;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;actin cytoskeleton#GO:0015629;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Cytoskeletal regulation by Rho GTPase#P00016>ARP2/3#P00511;Integrin signalling pathway#P00034>Arp2/3#P00912 IXOSC|EnsemblGenome=LOC8050557|UniProtKB=A0ACM8F713 A0ACM8F713 LOC8050557 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120838987|UniProtKB=A0ACM8FEU6 A0ACM8FEU6 PTHR42918:SF18 LYSYL-TRNA SYNTHETASE LYSINE--TRNA LIGASE catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120849284|UniProtKB=A0ACM8F7F0 A0ACM8F7F0 LOC120849284 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8028757|UniProtKB=A0ACM8DN87 A0ACM8DN87 Trf2 PTHR10126:SF69 TATA-BOX BINDING PROTEIN TATA BOX-BINDING PROTEIN-LIKE 1 nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;DNA-templated transcription initiation#GO:0006352 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;General transcription by RNA polymerase I#P00022>TBP#P00657;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;General transcription regulation#P00023>TBP#P00670 IXOSC|EnsemblGenome=LOC8052287|UniProtKB=A0ACM8E2J7 A0ACM8E2J7 LOC8052287 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8030552|UniProtKB=A0ACM8FVF4 A0ACM8FVF4 LOC8030552 PTHR15735:SF25 FCH AND DOUBLE SH3 DOMAINS PROTEIN PROTEIN NERVOUS WRECK phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cellular component biogenesis#GO:0044087;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;chemical synaptic transmission#GO:0007268;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cell communication#GO:0007154;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537;regulation of actin filament length#GO:0030832;regulation of actin filament polymerization#GO:0030833;regulation of actin polymerization or depolymerization#GO:0008064;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;membrane organization#GO:0061024;regulation of actin cytoskeleton organization#GO:0032956;synaptic signaling#GO:0099536;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;neuromuscular synaptic transmission#GO:0007274;regulation of actin filament-based process#GO:0032970 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;recycling endosome#GO:0055037;cell junction#GO:0030054;neuromuscular junction#GO:0031594 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC8023978|UniProtKB=A0ACM8E872 A0ACM8E872 Ankle2 PTHR12349:SF4 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 protein phosphatase binding#GO:0019903;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;cellular component assembly#GO:0022607;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;nuclear envelope organization#GO:0006998;mitotic cell cycle process#GO:1903047;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;membrane assembly#GO:0071709;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;organelle fission#GO:0048285 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8051841|UniProtKB=A0ACM8DLZ3 A0ACM8DLZ3 Maf1 PTHR22504:SF0 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 REPRESSOR OF RNA POLYMERASE III TRANSCRIPTION MAF1 HOMOLOG protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8033668|UniProtKB=A0ACM8FPT8 A0ACM8FPT8 LOC8033668 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC121045622|UniProtKB=A0ACM8FQ55 A0ACM8FQ55 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8033577|UniProtKB=A0ACM8EV07 A0ACM8EV07 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256 IXOSC|EnsemblGenome=LOC120843205|UniProtKB=A0ACM8EWM7 A0ACM8EWM7 LOC120843206 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8050813|UniProtKB=A0ACM8EBW2 A0ACM8EBW2 LOC8050813 PTHR31206:SF1 LP10445P LP10445P IXOSC|EnsemblGenome=LOC115310468|UniProtKB=A0ACM8DPZ5 A0ACM8DPZ5 Vps13 PTHR16166:SF147 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 INTERMEMBRANE LIPID TRANSFER PROTEIN VPS13 lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intermembrane lipid transfer#GO:0120009;metabolic process#GO:0008152;transport#GO:0006810;lipid transport#GO:0006869;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;macroautophagy#GO:0016236;organelle organization#GO:0006996;macromolecule localization#GO:0033036;autophagy#GO:0006914;cellular process#GO:0009987;localization#GO:0051179;process utilizing autophagic mechanism#GO:0061919;lipid localization#GO:0010876;catabolic process#GO:0009056;cellular component organization#GO:0016043 mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;outer membrane#GO:0019867;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120846069|UniProtKB=A0ACM8F1G1 A0ACM8F1G1 LOC120846069 PTHR33426:SF52 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115319313|UniProtKB=A0ACM8ER45 A0ACM8ER45 LOC115319313 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121835458|UniProtKB=A0ACM8FU34 A0ACM8FU34 LOC121835458 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152 intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8034723|UniProtKB=A0ACM8DYP2 A0ACM8DYP2 LOC8034723 PTHR12706:SF30 STRAWBERRY NOTCH-RELATED PROTEIN STRAWBERRY NOTCH-RELATED IXOSC|EnsemblGenome=LOC8032328|UniProtKB=A0ACM8E2Z3 A0ACM8E2Z3 LOC8032328 PTHR22093:SF0 LEUKOCYTE RECEPTOR CLUSTER LRC MEMBER 1 LEUKOCYTE RECEPTOR CLUSTER MEMBER 1 IXOSC|EnsemblGenome=LOC115314648|UniProtKB=A0ACM8FAN2 A0ACM8FAN2 LOC115314648 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029122|UniProtKB=A0ACM8DHM9 A0ACM8DHM9 LOC8029122 PTHR45881:SF1 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED FORK HEAD PROTEIN HOMOLOG 2 IXOSC|EnsemblGenome=LOC121837088|UniProtKB=A0ACM8G3E0 A0ACM8G3E0 LOC121837088 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320956|UniProtKB=A0ACM8G8U9 A0ACM8G8U9 LOC115320956 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327759|UniProtKB=A0ACM8E8S0 A0ACM8E8S0 LOC115327759 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120844813|UniProtKB=A0ACM8EZL7 A0ACM8EZL7 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8030117|UniProtKB=A0ACM8FRN1 A0ACM8FRN1 LOC8030117 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8034898|UniProtKB=A0ACM8E5U1 A0ACM8E5U1 LOC8034898 PTHR10105:SF2 SELENOPROTEIN P SELENOPROTEIN PB-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8051611|UniProtKB=A0ACM8DQT0 A0ACM8DQT0 LOC8051611 PTHR22198:SF1 FERM DOMAIN-CONTAINING PROTEIN DUF7153 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838909|UniProtKB=A0ACM8EL07 A0ACM8EL07 LOC120838909 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115326350|UniProtKB=A0ACM8G4I4 A0ACM8G4I4 LOC115326350 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324820|UniProtKB=A0ACM8EWZ3 A0ACM8EWZ3 LOC115324820 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8035596|UniProtKB=A0ACM8DJS0 A0ACM8DJS0 LOC8035596 PTHR46535:SF1 NEDD4-BINDING PROTEIN 2 NEDD4-BINDING PROTEIN 2 endonuclease activity#GO:0004519;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 IXOSC|EnsemblGenome=LOC8035268|UniProtKB=A0ACM8DNG9 A0ACM8DNG9 LOC8035268 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179;amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8043512|UniProtKB=A0ACM8FBJ1 A0ACM8FBJ1 LOC8043512 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051749|UniProtKB=A0ACM8FGW0 A0ACM8FGW0 Fak PTHR46221:SF9 FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER FOCAL ADHESION KINASE 1-RELATED VEGF signaling pathway#P00056>FAK#P01420;Integrin signalling pathway#P00034>FAK#P00932;Angiogenesis#P00005>FAK#P00209 IXOSC|EnsemblGenome=LOC120836079|UniProtKB=A0ACM8F5I3 A0ACM8F5I3 LOC120836079 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115311647|UniProtKB=A0ACM8F226 A0ACM8F226 LOC115311647 PTHR43245:SF51 BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA HYDROXY-DELTA-5-STEROID DEHYDROGENASE, 3 BETA- AND STEROID DELTA-ISOMERASE 1 IXOSC|EnsemblGenome=LOC8031928|UniProtKB=A0ACM8G5H6 A0ACM8G5H6 LOC8031928 PTHR37970:SF1 PROTEIN CBG08587 SERINE-RICH ADHESIN FOR PLATELETS IXOSC|EnsemblGenome=LOC8031867|UniProtKB=A0ACM8E3W6 A0ACM8E3W6 Cog8 PTHR21311:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8 establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;intra-Golgi vesicle-mediated transport#GO:0006891;retrograde transport, vesicle recycling within Golgi#GO:0000301 membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;intracellular anatomical structure#GO:0005622;COG complex#GO:0017119;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121833772|UniProtKB=A0ACM8FMM5 A0ACM8FMM5 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8023562|UniProtKB=A0ACM8FHF8 A0ACM8FHF8 LOC8023562 PTHR24364:SF18 LP06937P LP06937P cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115333096|UniProtKB=A0ACM8G8B2 A0ACM8G8B2 LOC115333096 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8041976|UniProtKB=A0ACM8DNR9 A0ACM8DNR9 LOC8041976 PTHR11849:SF282 ETS ETV5-RELATED PROTEIN ETS96B DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120843332|UniProtKB=A0ACM8G4V0 A0ACM8G4V0 LOC120843332 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040113|UniProtKB=A0ACM8DUT9 A0ACM8DUT9 LOC8040113 PTHR22948:SF79 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8038593|UniProtKB=A0ACM8EY39 A0ACM8EY39 Prp8 PTHR11140:SF0 PRE-MRNA SPLICING FACTOR PRP8 PRE-MRNA-PROCESSING-SPLICING FACTOR 8 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8025111|UniProtKB=A0ACM8DUG3 A0ACM8DUG3 LOC8025111 PTHR32247:SF3 DIABLO HOMOLOG, MITOCHONDRIAL DIABLO IAP-BINDING MITOCHONDRIAL PROTEIN intracellular signal transduction#GO:0035556;intrinsic apoptotic signaling pathway#GO:0097193;neuron apoptotic process#GO:0051402;cell communication#GO:0007154;apoptotic process#GO:0006915;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;apoptotic signaling pathway#GO:0097190;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 Apoptosis signaling pathway#P00006>Smac/Diablo#P00309 IXOSC|EnsemblGenome=LOC115323400|UniProtKB=A0ACM8F590 A0ACM8F590 LOC115323400 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC115308741|UniProtKB=A0ACM8DMY2 A0ACM8DMY2 LOC115308741 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8030665|UniProtKB=A0ACM8FEV8 A0ACM8FEV8 Alg13 PTHR12867:SF6 GLYCOSYL TRANSFERASE-RELATED UDP-N-ACETYLGLUCOSAMINE TRANSFERASE SUBUNIT ALG13 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058 transferase#PC00220 IXOSC|EnsemblGenome=LOC8052004|UniProtKB=A0ACM8G7U0 A0ACM8G7U0 LOC8052004 PTHR11702:SF43 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED GTP-BINDING PROTEIN 10 hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115331448|UniProtKB=A0ACM8EFT9 A0ACM8EFT9 LOC115331448 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120847368|UniProtKB=A0ACM8F3V2 A0ACM8F3V2 LOC120847368 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039127|UniProtKB=A0ACM8E0T9 A0ACM8E0T9 LOC8039127 PTHR31859:SF9 TETRATRICOPEPTIDE REPEAT PROTEIN 39 FAMILY MEMBER TETRATRICOPEPTIDE REPEAT PROTEIN TTC-39B IXOSC|EnsemblGenome=LOC8050723|UniProtKB=A0ACM8EST3 A0ACM8EST3 LOC8050723 PTHR10996:SF277 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC115327345|UniProtKB=A0ACM8E8E5 A0ACM8E8E5 LOC115327345 PTHR13281:SF0 TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL TRANSMEMBRANE PROTEIN 70, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967 IXOSC|EnsemblGenome=LOC115312179|UniProtKB=A0ACM8DRQ7 A0ACM8DRQ7 LOC115312179 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121837760|UniProtKB=A0ACM8G4P3 A0ACM8G4P3 LOC121837760 PTHR42923:SF3 PROTOPORPHYRINOGEN OXIDASE PROTOPORPHYRINOGEN OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Protoporphyrinogen oxidase#P02976 IXOSC|EnsemblGenome=LOC115310861|UniProtKB=A0ACM8EXK6 A0ACM8EXK6 LOC115310861 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED binding#GO:0005488;catalytic activity#GO:0003824;small molecule binding#GO:0036094;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8050881|UniProtKB=A0ACM8G7L0 A0ACM8G7L0 LOC8050881 PTHR10219:SF25 GLYCOLIPID TRANSFER PROTEIN-RELATED RH52220P lipid binding#GO:0008289;lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;lipid carrier activity#GO:0005319;ion binding#GO:0043167;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid binding#GO:0005543 transport#GO:0006810;lipid localization#GO:0010876;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;membrane organization#GO:0061024;ceramide transport#GO:0035627;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115329215|UniProtKB=A0ACM8EA70 A0ACM8EA70 LOC115329215 PTHR19300:SF66 BETA-1,4-GALACTOSYLTRANSFERASE BETA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE A hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC121835651|UniProtKB=A0ACM8FWC4 A0ACM8FWC4 LOC121835651 PTHR23226:SF468 ZINC FINGER AND SCAN DOMAIN-CONTAINING SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120838903|UniProtKB=A0ACM8G8T0 A0ACM8G8T0 LOC120838903 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8052028|UniProtKB=A0ACM8DLI2 A0ACM8DLI2 RpL5 PTHR23410:SF12 RIBOSOMAL PROTEIN L5-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL18 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;positive regulation of protein metabolic process#GO:0051247;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;ribosomal large subunit assembly#GO:0000027;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;organelle assembly#GO:0070925;positive regulation of translation#GO:0045727;protein-RNA complex assembly#GO:0022618;positive regulation of biosynthetic process#GO:0009891 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8025889|UniProtKB=A0ACM8DZD1 A0ACM8DZD1 LOC8025889 PTHR12599:SF0 PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE lyase#PC00144;dehydratase#PC00091 IXOSC|EnsemblGenome=LOC8033665|UniProtKB=A0ACM8EV21 A0ACM8EV21 LOC8033665 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC8038091|UniProtKB=A0ACM8E5F4 A0ACM8E5F4 LOC8038091 PTHR23254:SF16 EIF4G DOMAIN PROTEIN CBP80_20-DEPENDENT TRANSLATION INITIATION FACTOR translation regulator activity#GO:0045182 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115324593|UniProtKB=A0ACM8F027 A0ACM8F027 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052131|UniProtKB=A0ACM8E637 A0ACM8E637 LOC8052131 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8031074|UniProtKB=A0ACM8DHW9 A0ACM8DHW9 LOC8031074 PTHR24264:SF91 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8024140|UniProtKB=A0ACM8EPD7 A0ACM8EPD7 LOC8024140 PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC115317290|UniProtKB=A0ACM8FKL9 A0ACM8FKL9 LOC115317290 PTHR24394:SF64 ZINC FINGER PROTEIN CENTROSOME-ASSOCIATED ZINC FINGER PROTEIN CP190 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8053542|UniProtKB=A0ACM8EUK2 A0ACM8EUK2 LOC8053542 PTHR10629:SF61 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 DNA binding#GO:0003677;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA methyltransferase#PC00013 IXOSC|EnsemblGenome=LOC8040320|UniProtKB=A0ACM8E8Y4 A0ACM8E8Y4 LOC8040320 PTHR11703:SF0 DEOXYHYPUSINE SYNTHASE DEOXYHYPUSINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152;biogenic amine metabolic process#GO:0006576 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120837001|UniProtKB=A0ACM8EH08 A0ACM8EH08 LOC120837001 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029102|UniProtKB=A0ACM8EEN0 A0ACM8EEN0 LOC8029102 PTHR11759:SF76 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8037542|UniProtKB=A0ACM8DNY0 A0ACM8DNY0 LOC8037542 PTHR12053:SF4 PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED CARBOXYPEPTIDASE Q catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;metalloexopeptidase activity#GO:0008235 peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115320437|UniProtKB=A0ACM8EWX8 A0ACM8EWX8 LOC115320437 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8037857|UniProtKB=A0ACM8E1G1 A0ACM8E1G1 LOC8037857 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8039525|UniProtKB=A0ACM8FCH1 A0ACM8FCH1 LOC8039525 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121835038|UniProtKB=A0ACM8FS15 A0ACM8FS15 LOC121835038 PTHR10082:SF60 INTEGRIN BETA SUBUNIT INTEGRIN BETA-PS protein binding#GO:0005515;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;binding#GO:0005488;signaling receptor binding#GO:0005102;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;signal transduction#GO:0007165;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;cell migration#GO:0016477;cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;signaling#GO:0023052;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589 signaling receptor complex#GO:0043235;anchoring junction#GO:0070161;integrin complex#GO:0008305;cell junction#GO:0030054;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;membrane#GO:0016020;membrane protein complex#GO:0098796;cell-substrate junction#GO:0030055;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 IXOSC|EnsemblGenome=LOC8038125|UniProtKB=A0ACM8DGL1 A0ACM8DGL1 LOC8038125 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8024119|UniProtKB=A0ACM8DY07 A0ACM8DY07 LOC8024119 PTHR20889:SF12 PHOSPHATASE, ORPHAN 1, 2 LP01149P hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8031501|UniProtKB=A0ACM8E8S3 A0ACM8E8S3 LOC8031501 PTHR22834:SF22 NUCLEAR FUSION PROTEIN FUS2 SH3 DOMAIN-CONTAINING GRB2-LIKE PROTEIN enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8052870|UniProtKB=A0ACM8DM00 A0ACM8DM00 LOC8052870 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115323386|UniProtKB=A0ACM8FMC9 A0ACM8FMC9 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8043970|UniProtKB=A0ACM8DM92 A0ACM8DM92 LOC8043970 PTHR12146:SF0 40S RIBOSOMAL PROTEIN S10 RIBOSOMAL PROTEIN S10 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115332227|UniProtKB=A0ACM8FEY7 A0ACM8FEY7 LOC115332227 PTHR11937:SF607 ACTIN ACTIN-42A-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 cytoskeleton-dependent cytokinesis#GO:0061640;cortical actin cytoskeleton organization#GO:0030866;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell division#GO:0051301;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>F-actin#P00858;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090;Cytoskeletal regulation by Rho GTPase#P00016>Actin#P00512;Huntington disease#P00029>Actin#P00807 IXOSC|EnsemblGenome=LOC8039820|UniProtKB=A0ACM8EPA9 A0ACM8EPA9 LOC8039820 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;catalytic activity#GO:0003824 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC8036266|UniProtKB=A0ACM8FC85 A0ACM8FC85 LOC8036266 PTHR24241:SF204 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR GONADOTROPIN-RELEASING HORMONE II RECEPTOR transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121832882|UniProtKB=A0ACM8FS24 A0ACM8FS24 LOC121832882 PTHR11022:SF80 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LC-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;pattern recognition receptor activity#GO:0038187;hydrolase activity#GO:0016787;molecular transducer activity#GO:0060089;peptidoglycan muralytic activity#GO:0061783;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to other organism#GO:0051707;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;response to external stimulus#GO:0009605;defense response#GO:0006952 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC115331637|UniProtKB=A0ACM8EC79 A0ACM8EC79 LOC115331637 PTHR45632:SF36 LD33804P RING ZINC FINGER-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121836190|UniProtKB=A0ACM8FXT6 A0ACM8FXT6 LOC121836190 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324 trans-synaptic signaling#GO:0099537;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;transport#GO:0006810;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;synaptic signaling#GO:0099536;cellular process#GO:0009987;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC8028213|UniProtKB=A0ACM8DJM8 A0ACM8DJM8 PTHR21719:SF2 FI06402P-RELATED FI06402P-RELATED cellular process#GO:0009987;embryo development#GO:0009790;cell development#GO:0048468;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501;cell migration#GO:0016477;cell motility#GO:0048870;cell differentiation#GO:0030154;embryonic organ development#GO:0048568;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;animal organ development#GO:0048513;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 IXOSC|EnsemblGenome=LOC120846446|UniProtKB=A0ACM8F245 A0ACM8F245 LOC120846446 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026950|UniProtKB=A0ACM8EF65 A0ACM8EF65 LOC8026950 PTHR18976:SF34 APOLIPOPROTEIN LIPID-BINDING PROTEIN transfer/carrier protein#PC00219;apolipoprotein#PC00052 IXOSC|EnsemblGenome=LOC115317843|UniProtKB=A0ACM8ERE7 A0ACM8ERE7 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327270|UniProtKB=A0ACM8E7I3 A0ACM8E7I3 LOC115327270 PTHR19237:SF20 NUCLEOBINDIN NUCLEOBINDIN 1 metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 calcium-binding protein#PC00060;calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC120840809|UniProtKB=A0ACM8EQA8 A0ACM8EQA8 LOC120840809 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC121834989|UniProtKB=A0ACM8FRT5 A0ACM8FRT5 LOC121834989 PTHR48228:SF8 SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE ALPHA-METHYLACYL-COA RACEMASE racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;steroid metabolic process#GO:0008202;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 IXOSC|EnsemblGenome=LOC120841038|UniProtKB=A0ACM8EQV3 A0ACM8EQV3 LOC120841038 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849502|UniProtKB=A0ACM8F897 A0ACM8F897 LOC120849502 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8024949|UniProtKB=A0ACM8E155 A0ACM8E155 LOC8024949 PTHR10918:SF7 HOMER HOMER, ISOFORM E protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102;G protein-coupled receptor binding#GO:0001664 cell surface receptor signaling pathway#GO:0007166;regulation of localization#GO:0032879;regulation of transport#GO:0051049;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of monoatomic ion transport#GO:0043269;regulation of calcium ion transport#GO:0051924;biological regulation#GO:0065007;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of metal ion transport#GO:0010959;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8038830|UniProtKB=A0ACM8DK87 A0ACM8DK87 LOC8038830 PTHR10026:SF7 CYCLIN CYCLIN-C cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887 regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138;kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC8023164|UniProtKB=A0ACM8E754 A0ACM8E754 LOC8023164 PTHR22838:SF4 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 13 binding#GO:0005488;chromatin binding#GO:0003682 IXOSC|EnsemblGenome=LOC120850047|UniProtKB=A0ACM8F8X7 A0ACM8F8X7 LOC120850047 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 IXOSC|EnsemblGenome=LOC8041612|UniProtKB=A0ACM8FFV5 A0ACM8FFV5 LOC8041612 PTHR11616:SF337 SODIUM/CHLORIDE DEPENDENT TRANSPORTER BLOATED TUBULES, ISOFORM B-RELATED symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;glycine transmembrane transporter activity#GO:0015187;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 glycine transport#GO:0015816;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;transport#GO:0006810;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;import into cell#GO:0098657;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115308175|UniProtKB=A0ACM8E799 A0ACM8E799 LOC115308175 PTHR13096:SF7 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 2 IXOSC|EnsemblGenome=LOC8027645|UniProtKB=A0ACM8FF98 A0ACM8FF98 LOC8027645 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115322204|UniProtKB=A0ACM8ELI0 A0ACM8ELI0 LOC115322204 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121836276|UniProtKB=A0ACM8FY75 A0ACM8FY75 LOC121836276 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120836420|UniProtKB=A0ACM8EF18 A0ACM8EF18 LOC120836420 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8030247|UniProtKB=A0ACM8DGH7 A0ACM8DGH7 LOC8030247 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8027498|UniProtKB=A0ACM8DJ56 A0ACM8DJ56 LOC8027498 PTHR16056:SF39 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN TESTIS-EXPRESSED PROTEIN 10 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8034905|UniProtKB=A0ACM8DJN9 A0ACM8DJN9 LOC8034905 PTHR24347:SF393 SERINE/THREONINE-PROTEIN KINASE SPAGHETTI-SQUASH ACTIVATOR, ISOFORM C kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>MLCK#P00514;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MLCK#P00877 IXOSC|EnsemblGenome=LOC8027602|UniProtKB=A0ACM8F2P4 A0ACM8F2P4 LOC8027602 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121048348|UniProtKB=A0ACM8G3K8 A0ACM8G3K8 LOC121048348 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115309252|UniProtKB=A0ACM8ER10 A0ACM8ER10 LOC115309252 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8037503|UniProtKB=A0ACM8FKW0 A0ACM8FKW0 LOC8037503 PTHR15422:SF45 OS05G0565100 PROTEIN ASCORBATE FERRIREDUCTASE (TRANSMEMBRANE) IXOSC|EnsemblGenome=LOC115323378|UniProtKB=A0ACM8FZH4 A0ACM8FZH4 LOC115323378 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8039763|UniProtKB=A0ACM8DXL2 A0ACM8DXL2 LOC8039763 PTHR14950:SF82 DICER-RELATED ENDORIBONUCLEASE DICER DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;binding#GO:0005488;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;hydrolase activity#GO:0016787;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;siRNA processing#GO:0030422;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;apoptotic DNA fragmentation#GO:0006309;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;RNA biosynthetic process#GO:0032774;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell death#GO:0008219;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120849133|UniProtKB=A0ACM8G8P1 A0ACM8G8P1 LOC121838552 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 transferase#PC00220 IXOSC|EnsemblGenome=LOC8052147|UniProtKB=A0ACM8DZ53 A0ACM8DZ53 LOC8052147 PTHR10996:SF277 2-HYDROXYACID DEHYDROGENASE-RELATED GLYOXYLATE REDUCTASE_HYDROXYPYRUVATE REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8029339|UniProtKB=A0ACM8DYU8 A0ACM8DYU8 Nhe1 PTHR10110:SF191 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER 8 proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;import into cell#GO:0098657 endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8023707|UniProtKB=A0ACM8DHE5 A0ACM8DHE5 LOC8023707 PTHR11829:SF402 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN FD3-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8034638|UniProtKB=A0ACM8EAE3 A0ACM8EAE3 LOC8034638 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115323941|UniProtKB=A0ACM8EN68 A0ACM8EN68 LOC115323941 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024447|UniProtKB=A0ACM8EZS8 A0ACM8EZS8 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8030991|UniProtKB=A0ACM8DYE6 A0ACM8DYE6 LOC8030991 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8033520|UniProtKB=A0ACM8E802 A0ACM8E802 LOC8033520 PTHR31328:SF2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 6 establishment of localization#GO:0051234;vesicle-mediated transport in synapse#GO:0099003;endosomal transport#GO:0016197;intracellular transport#GO:0046907;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;synaptic vesicle recycling#GO:0036465;vesicle-mediated transport#GO:0016192;establishment of vesicle localization#GO:0051650;cellular pigmentation#GO:0033059;establishment of localization in cell#GO:0051649;vesicle localization#GO:0051648;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;organelle localization#GO:0051640;pigmentation#GO:0043473;establishment of organelle localization#GO:0051656 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;BLOC-1 complex#GO:0031083;actin filament bundle#GO:0032432;vesicle#GO:0031982;postsynapse#GO:0098794;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;stress fiber#GO:0001725;cytoskeleton#GO:0005856;cell-cell contact zone#GO:0044291;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;neuromuscular junction#GO:0031594;cell junction#GO:0030054;actomyosin#GO:0042641;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133 IXOSC|EnsemblGenome=LOC115316925|UniProtKB=A0ACM8F161 A0ACM8F161 LOC115316925 PTHR45656:SF4 PROTEIN CBR-CLEC-78 COMPLEMENT COMPONENT RECEPTOR 1-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8035421|UniProtKB=A0ACM8DJS9 A0ACM8DJS9 LOC8035421 PTHR21461:SF40 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN BETA-1,4-GALACTOSYLTRANSFERASE GALT-1 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120843915|UniProtKB=A0ACM8EX48 A0ACM8EX48 LOC120843915 PTHR23192:SF92 OLFACTOMEDIN-RELATED FI21454P1 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 structural protein#PC00211 IXOSC|EnsemblGenome=LOC8039010|UniProtKB=A0ACM8EA44 A0ACM8EA44 UbcE2M PTHR24067:SF384 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN CONJUGATING ENZYME E2 M cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8024205|UniProtKB=A0ACM8DI07 A0ACM8DI07 LOC8024205 PTHR10920:SF13 RIBOSOMAL RNA METHYLTRANSFERASE PRE-RRNA 2'-O-RIBOSE RNA METHYLTRANSFERASE FTSJ3 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity, acting on RNA#GO:0140098;O-methyltransferase activity#GO:0008171;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;maturation of LSU-rRNA#GO:0000470;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;rRNA modification#GO:0000154;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;RNA metabolic process#GO:0016070;methylation#GO:0032259;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8031604|UniProtKB=A0ACM8EBD9 A0ACM8EBD9 LOC8031604 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8025286|UniProtKB=A0ACM8E234 A0ACM8E234 LOC8025286 PTHR20951:SF2 C13ORF1 PROTEIN-RELATED SPRY DOMAIN-CONTAINING PROTEIN 7 IXOSC|EnsemblGenome=LOC8053571|UniProtKB=A0ACM8E8I2 A0ACM8E8I2 Usp16-45 PTHR21646:SF39 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 16 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC121835411|UniProtKB=A0ACM8FTS6 A0ACM8FTS6 LOC121835411 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8023847|UniProtKB=A0ACM8EPM1 A0ACM8EPM1 LOC8023847 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8043828|UniProtKB=A0ACM8F496 A0ACM8F496 LOC8043828 PTHR10024:SF227 SYNAPTOTAGMIN SYNAPTOTAGMIN 1 binding#GO:0005488;phospholipid binding#GO:0005543;SNARE binding#GO:0000149;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;protein binding#GO:0005515 regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;positive regulation of organelle organization#GO:0010638;cellular localization#GO:0051641;regulation of signaling#GO:0023051;positive regulation of cellular component organization#GO:0051130;regulation of neurotransmitter transport#GO:0051588;regulation of synaptic vesicle exocytosis#GO:2000300;export from cell#GO:0140352;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;positive regulation of vesicle fusion#GO:0031340;exocytosis#GO:0006887;regulation of localization#GO:0032879;regulation of transport#GO:0051049;vesicle-mediated transport in synapse#GO:0099003;regulated exocytosis#GO:0045055;neurotransmitter transport#GO:0006836;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;synaptic signaling#GO:0099536;regulation of exocytosis#GO:0017157;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion#GO:0051046;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522 synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;axon#GO:0030424;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;plasma membrane#GO:0005886;organelle membrane#GO:0031090;intracellular vesicle#GO:0097708;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;secretory vesicle#GO:0099503;neuron projection#GO:0043005;presynapse#GO:0098793;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588 membrane trafficking regulatory protein#PC00151 Synaptic vesicle trafficking#P05734>Synaptotagmin#P05769 IXOSC|EnsemblGenome=LOC8041790|UniProtKB=A0ACM8EF15 A0ACM8EF15 LOC8041790 PTHR11177:SF144 CHITINASE CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 chitin metabolic process#GO:0006030;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121837352|UniProtKB=A0ACM8G395 A0ACM8G395 LOC121837352 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8034167|UniProtKB=A0ACM8FEB1 A0ACM8FEB1 Pcf11 PTHR15921:SF3 PRE-MRNA CLEAVAGE COMPLEX II PRE-MRNA CLEAVAGE COMPLEX 2 PROTEIN PCF11 RNA polymerase II complex binding#GO:0000993;RNA binding#GO:0003723;protein binding#GO:0005515;enzyme binding#GO:0019899;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase binding#GO:0070063 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription termination#GO:0006353;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8039434|UniProtKB=A0ACM8DQW8 A0ACM8DQW8 Setd3 PTHR13271:SF163 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE ACTIN-HISTIDINE N-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120846776|UniProtKB=A0ACM8F4L7 A0ACM8F4L7 LOC121836277 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837694|UniProtKB=A0ACM8FDY9 A0ACM8FDY9 LOC120837694 PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cellular process#GO:0009987;cell cycle process#GO:0022402;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8053141|UniProtKB=A0ACM8DNY2 A0ACM8DNY2 LOC8053141 PTHR13421:SF16 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 3 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA transcription#GO:0009301 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8051866|UniProtKB=A0ACM8FGY0 A0ACM8FGY0 LOC8051866 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115308973|UniProtKB=A0ACM8DN76 A0ACM8DN76 LOC115308973 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836880|UniProtKB=A0ACM8G216 A0ACM8G216 LOC121836880 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8028940|UniProtKB=A0ACM8DHD3 A0ACM8DHD3 LOC8028940 PTHR45672:SF3 PROTEIN DISULFIDE-ISOMERASE C17H9.14C-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 5 isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121836007|UniProtKB=A0ACM8FXX8 A0ACM8FXX8 LOC121836007 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318835|UniProtKB=A0ACM8DZ78 A0ACM8DZ78 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8054078|UniProtKB=A0ACM8EBZ5 A0ACM8EBZ5 LOC8054078 PTHR23291:SF133 BAX INHIBITOR-RELATED BAX INHIBITOR 1 molecular function inhibitor activity#GO:0140678;calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;enzyme regulator activity#GO:0030234;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;enzyme inhibitor activity#GO:0004857;passive transmembrane transporter activity#GO:0022803;molecular function regulator activity#GO:0098772;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 cellular response to unfolded protein#GO:0034620;negative regulation of signaling#GO:0023057;cellular response to topologically incorrect protein#GO:0035967;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of apoptotic signaling pathway#GO:2001234;cellular response to stress#GO:0033554;response to unfolded protein#GO:0006986;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;response to topologically incorrect protein#GO:0035966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;response to stress#GO:0006950;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 ion channel#PC00133;transporter#PC00227 Apoptosis signaling pathway#P00006>Bi1#P00277 IXOSC|EnsemblGenome=LOC8028712|UniProtKB=A0ACM8EDB7 A0ACM8EDB7 LOC8028712 PTHR20963:SF56 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;extracellular region#GO:0005576;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121836118|UniProtKB=A0ACM8FWU1 A0ACM8FWU1 LOC121836118 PTHR31716:SF1 PROTEIN FMC1 HOMOLOG PROTEIN FMC1 HOMOLOG cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC120850194|UniProtKB=A0ACM8F9H8 A0ACM8F9H8 LOC120850194 PTHR24393:SF175 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120847751|UniProtKB=A0ACM8F4S7 A0ACM8F4S7 LOC120847751 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035030|UniProtKB=A0ACM8EKJ0 A0ACM8EKJ0 LOC8035030 PTHR46708:SF2 TENASCIN FIBRONECTIN-LIKE extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8039276|UniProtKB=A0ACM8E2H6 A0ACM8E2H6 Ddr PTHR24416:SF634 TYROSINE-PROTEIN KINASE RECEPTOR DISCOIDIN DOMAIN RECEPTOR, ISOFORM F signaling receptor activity#GO:0038023;kinase activity#GO:0016301;transferase activity#GO:0016740;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;collagen binding#GO:0005518;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089 positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120836227|UniProtKB=A0ACM8EN12 A0ACM8EN12 LOC120836227 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8039321|UniProtKB=A0ACM8DKD7 A0ACM8DKD7 LOC8039321 PTHR11214:SF410 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 6 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 carbohydrate derivative biosynthetic process#GO:1901137;glycosaminoglycan biosynthetic process#GO:0006024;macromolecule metabolic process#GO:0043170;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;aminoglycan biosynthetic process#GO:0006023;glycosaminoglycan metabolic process#GO:0030203 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120842406|UniProtKB=A0ACM8ETH2 A0ACM8ETH2 LOC120842406 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035874|UniProtKB=A0ACM8E5H7 A0ACM8E5H7 T3dh PTHR11496:SF83 ALCOHOL DEHYDROGENASE HYDROXYACID-OXOACID TRANSHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120840315|UniProtKB=A0ACM8ENM1 A0ACM8ENM1 LOC120840315 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115320264|UniProtKB=A0ACM8F640 A0ACM8F640 LOC115320264 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843858|UniProtKB=A0ACM8EWR2 A0ACM8EWR2 mEFTs PTHR11741:SF0 ELONGATION FACTOR TS ELONGATION FACTOR TS, MITOCHONDRIAL translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC8035893|UniProtKB=A0ACM8DY86 A0ACM8DY86 Tfb1 PTHR12856:SF0 TRANSCRIPTION INITIATION FACTOR IIH-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 1 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;transcription factor TFIIH holo complex#GO:0005675;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transcription factor TFIIH core complex#GO:0000439;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911 RNA metabolism protein#PC00031;general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 IXOSC|EnsemblGenome=LOC120844854|UniProtKB=A0ACM8EZD9 A0ACM8EZD9 LOC120844854 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 IXOSC|EnsemblGenome=LOC121834192|UniProtKB=A0ACM8FPN7 A0ACM8FPN7 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037864|UniProtKB=A0ACM8DI96 A0ACM8DI96 LOC8037864 PTHR16560:SF3 ALPHA-2-MACROGLOBULIN RECEPTOR-ASSOCIATED PROTEIN LD29322P regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of cellular component organization#GO:0051128;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121835876|UniProtKB=A0ACM8FVI9 A0ACM8FVI9 LOC121835876 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115319949|UniProtKB=A0ACM8E0G7 A0ACM8E0G7 LOC115319949 PTHR11122:SF13 APOSPORY-ASSOCIATED PROTEIN C-RELATED GLUCOSE-6-PHOSPHATE 1-EPIMERASE catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;isomerase activity#GO:0016853 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8031235|UniProtKB=A0ACM8EEN1 A0ACM8EEN1 LOC8031235 PTHR24031:SF54 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX10-RELATED metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC121048606|UniProtKB=A0ACM8FHG1 A0ACM8FHG1 LOC121048606 PTHR24356:SF450 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TRICORNERED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;establishment or maintenance of cell polarity#GO:0007163;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120843145|UniProtKB=A0ACM8EVB4 A0ACM8EVB4 LOC120843145 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8038647|UniProtKB=A0ACM8DK70 A0ACM8DK70 LOC8038647 PTHR12137:SF54 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220 IXOSC|EnsemblGenome=LOC115329918|UniProtKB=A0ACM8EBK6 A0ACM8EBK6 LOC115329918 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120842160|UniProtKB=A0ACM8EUA3 A0ACM8EUA3 LOC120842160 PTHR47501:SF5 TRANSPOSASE-RELATED BED-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115324933|UniProtKB=A0ACM8F220 A0ACM8F220 LOC115324933 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8029422|UniProtKB=A0ACM8DI33 A0ACM8DI33 RpL7 PTHR11524:SF16 60S RIBOSOMAL PROTEIN L7 LARGE RIBOSOMAL SUBUNIT PROTEIN UL30 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8034977|UniProtKB=A0ACM8E1H0 A0ACM8E1H0 LOC8034977 PTHR11081:SF70 FLAP ENDONUCLEASE FAMILY MEMBER FLAP ENDONUCLEASE GEN HOMOLOG 1 DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;four-way junction DNA binding#GO:0000400;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261 exodeoxyribonuclease#PC00098;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8039348|UniProtKB=A0ACM8DSY3 A0ACM8DSY3 gammaSnap1 PTHR13768:SF2 SOLUBLE NSF ATTACHMENT PROTEIN SNAP GAMMA-SOLUBLE NSF ATTACHMENT PROTEIN membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8051893|UniProtKB=A0ACM8E816 A0ACM8E816 LOC8051893 PTHR23025:SF3 TRIACYLGLYCEROL LIPASE HORMONE-SENSITIVE LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;triacylglycerol lipase activity#GO:0004806;lipase activity#GO:0016298;catalytic activity#GO:0003824 glycerolipid metabolic process#GO:0046486;catabolic process#GO:0009056;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;neutral lipid metabolic process#GO:0006638;acylglycerol catabolic process#GO:0046464;metabolic process#GO:0008152;triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503;acylglycerol metabolic process#GO:0006639;neutral lipid catabolic process#GO:0046461;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 IXOSC|EnsemblGenome=LOC120838717|UniProtKB=A0ACM8EJR8 A0ACM8EJR8 LOC120838717 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC115317253|UniProtKB=A0ACM8FBB0 A0ACM8FBB0 LOC115317253 PTHR34179:SF1 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 TUMOR PROTEIN P53-INDUCIBLE PROTEIN 13 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC121838298|UniProtKB=A0ACM8G7I8 A0ACM8G7I8 LOC121838298 PTHR21236:SF2 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 structural protein#PC00211 IXOSC|EnsemblGenome=LOC8032736|UniProtKB=A0ACM8E5I8 A0ACM8E5I8 mwh PTHR45857:SF4 FORMIN-LIKE PROTEIN MULTIPLE WING HAIRS, ISOFORM C IXOSC|EnsemblGenome=LOC120845888|UniProtKB=A0ACM8F1W4 A0ACM8F1W4 LOC120845888 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8043718|UniProtKB=A0ACM8EE54 A0ACM8EE54 LOC8043718 PTHR12086:SF9 EF-HAND DOMAIN C-TERMINAL CONTAINING PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488 cytoskeleton-dependent cytokinesis#GO:0061640;cilium-dependent cell motility#GO:0060285;microtubule cytoskeleton organization#GO:0000226;cilium or flagellum-dependent cell motility#GO:0001539;cytokinesis#GO:0000910;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;cell motility#GO:0048870;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996 plasma membrane bounded cell projection#GO:0120025;mitotic spindle#GO:0072686;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;axonemal microtubule#GO:0005879;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;axoneme#GO:0005930;microtubule#GO:0005874;cilium#GO:0005929;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;spindle#GO:0005819 calmodulin-related#PC00061;calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC115309113|UniProtKB=A0ACM8F357 A0ACM8F357 LOC115309113 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8042918|UniProtKB=A0ACM8FHP6 A0ACM8FHP6 eIF5 PTHR23001:SF7 EUKARYOTIC TRANSLATION INITIATION FACTOR EUKARYOTIC TRANSLATION INITIATION FACTOR 5 binding#GO:0005488;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;translation factor activity#GO:0180051;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;translation initiation factor binding#GO:0031369;translation initiation factor activity#GO:0003743;molecular function regulator activity#GO:0098772 metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;translation#GO:0006412;translational initiation#GO:0006413;cytoplasmic translational initiation#GO:0002183;protein-RNA complex assembly#GO:0022618;protein metabolic process#GO:0019538;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 IXOSC|EnsemblGenome=LOC115311746|UniProtKB=A0ACM8DRE0 A0ACM8DRE0 Prp5 PTHR47958:SF221 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8031100|UniProtKB=A0ACM8FEJ0 A0ACM8FEJ0 PTHR21727:SF0 PHOSPHORYLATED CTD INTERACTING FACTOR 1 MRNA (2'-O-METHYLADENOSINE-N(6)-)-METHYLTRANSFERASE intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120846196|UniProtKB=A0ACM8F123 A0ACM8F123 LOC120846196 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115326167|UniProtKB=A0ACM8FII6 A0ACM8FII6 LOC115326167 PTHR12178:SF10 EF-HAND DOMAIN-CONTAINING PROTEIN N-TERMINAL EF-HAND CALCIUM-BINDING PROTEIN 1-LIKE ISOFORM X1 regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8034251|UniProtKB=A0ACM8EBY4 A0ACM8EBY4 eIF6 PTHR10784:SF0 TRANSLATION INITIATION FACTOR 6 EUKARYOTIC TRANSLATION INITIATION FACTOR 6 ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;ribosomal large subunit binding#GO:0043023;binding#GO:0005488 cellular localization#GO:0051641;RNA metabolic process#GO:0016070;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;establishment of organelle localization#GO:0051656;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;protein-RNA complex assembly#GO:0022618;nuclear transport#GO:0051169;rRNA processing#GO:0006364;nuclear export#GO:0051168;organelle assembly#GO:0070925;organelle localization#GO:0051640;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;ribosomal subunit export from nucleus#GO:0000054;rRNA metabolic process#GO:0016072;intracellular transport#GO:0046907;transport#GO:0006810;maturation of LSU-rRNA#GO:0000470;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC115315261|UniProtKB=A0ACM8DUR1 A0ACM8DUR1 LOC115315261 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8042178|UniProtKB=A0ACM8DKW1 A0ACM8DKW1 LOC8042178 PTHR28646:SF2 TRANSMEMBRANE PROTEIN 201 FI17509P1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488 establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;nuclear migration#GO:0007097;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;intracellular transport#GO:0046907 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;membrane#GO:0016020;organelle envelope#GO:0031967;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8038298|UniProtKB=A0ACM8DM70 A0ACM8DM70 LOC8038298 PTHR24365:SF555 TOLL-LIKE RECEPTOR MSTPROX-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121837386|UniProtKB=A0ACM8G330 A0ACM8G330 LOC121837386 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120848300|UniProtKB=A0ACM8F6H3 A0ACM8F6H3 LOC120848300 PTHR46481:SF16 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 BED-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028573|UniProtKB=A0ACM8FI48 A0ACM8FI48 LOC8028573 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115322953|UniProtKB=A0ACM8ET88 A0ACM8ET88 LOC115322953 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120841602|UniProtKB=A0ACM8ES42 A0ACM8ES42 LOC120841602 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8041699|UniProtKB=A0ACM8DN03 A0ACM8DN03 LOC8041699 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120839630|UniProtKB=A0ACM8EMR6 A0ACM8EMR6 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC120839027|UniProtKB=A0ACM8EM76 A0ACM8EM76 LOC120839027 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316716|UniProtKB=A0ACM8DW71 A0ACM8DW71 LOC115316716 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115320319|UniProtKB=A0ACM8FZG4 A0ACM8FZG4 LOC115320319 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115322954|UniProtKB=A0ACM8ET83 A0ACM8ET83 LOC115322954 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115316844|UniProtKB=A0ACM8EHG8 A0ACM8EHG8 LOC115316844 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC115309199|UniProtKB=A0ACM8FXJ0 A0ACM8FXJ0 LOC115309199 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120844937|UniProtKB=A0ACM8F138 A0ACM8F138 LOC120844937 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8051260|UniProtKB=A0ACM8G1D2 A0ACM8G1D2 LOC8051260 PTHR13743:SF123 BEIGE/BEACH-RELATED PROTEIN FAN cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8050878|UniProtKB=A0ACM8E717 A0ACM8E717 LOC8050878 PTHR12911:SF48 SAD1/UNC-84-LIKE PROTEIN-RELATED KLAROID PROTEIN-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-membrane adaptor activity#GO:0043495 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8023412|UniProtKB=A0ACM8DMR8 A0ACM8DMR8 Rrp46 PTHR11953:SF1 EXOSOME COMPLEX COMPONENT EXOSOME COMPLEX COMPONENT RRP46 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;nuclear mRNA surveillance#GO:0071028;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;snRNA metabolic process#GO:0016073;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;snRNA 3'-end processing#GO:0034472;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 exoribonuclease#PC00099;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121834082|UniProtKB=A0ACM8FQ34 A0ACM8FQ34 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115309863|UniProtKB=A0ACM8F1X1 A0ACM8F1X1 LOC115309863 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8043268|UniProtKB=A0ACM8EDP2 A0ACM8EDP2 ND-B22 PTHR12868:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B22 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 9 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8031202|UniProtKB=A0ACM8EY21 A0ACM8EY21 LOC8031202 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8041101|UniProtKB=A0ACM8DT24 A0ACM8DT24 LOC8041101 PTHR47970:SF35 KINESIN-LIKE PROTEIN KIF11 ARMADILLO REPEAT-CONTAINING KINESIN-LIKE PROTEIN microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC121834244|UniProtKB=A0ACM8FQJ4 A0ACM8FQJ4 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386 meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;nucleobase-containing compound metabolic process#GO:0006139;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;reproductive process#GO:0022414;homologous recombination#GO:0035825 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC115325323|UniProtKB=A0ACM8F1H7 A0ACM8F1H7 LOC120846197 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314030|UniProtKB=A0ACM8DTN6 A0ACM8DTN6 LOC115314030 PTHR13005:SF4 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8023073|UniProtKB=A0ACM8G8P4 A0ACM8G8P4 LOC8023073 PTHR11920:SF335 GUANYLYL CYCLASE GUANYLATE CYCLASE molecular transducer activity#GO:0060089;lyase activity#GO:0016829;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975 ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanylate cyclase#PC00114;lyase#PC00144 IXOSC|EnsemblGenome=LOC8028916|UniProtKB=A0ACM8DHC2 A0ACM8DHC2 LOC8028916 PTHR46641:SF11 FMRFAMIDE RECEPTOR-RELATED PROCTOLIN RECEPTOR, ISOFORM A transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8040034|UniProtKB=A0ACM8DKH0 A0ACM8DKH0 PTHR11080:SF2 PYRAZINAMIDASE/NICOTINAMIDASE NICOTINAMIDASE amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 IXOSC|EnsemblGenome=LOC8040729|UniProtKB=A0ACM8G1D8 A0ACM8G1D8 LOC8040729 PTHR46237:SF2 CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER CYTOCHROME B5 REDUCTASE 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;superoxide metabolic process#GO:0006801 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 reductase#PC00198 IXOSC|EnsemblGenome=LOC115329504|UniProtKB=A0ACM8EA30 A0ACM8EA30 eEF1gamma PTHR43986:SF1 ELONGATION FACTOR 1-GAMMA ELONGATION FACTOR 1-GAMMA primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8052969|UniProtKB=A0ACM8EI15 A0ACM8EI15 LOC8052969 PTHR11219:SF69 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-A protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120842941|UniProtKB=A0ACM8EV19 A0ACM8EV19 LOC120842941 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8038053|UniProtKB=A0ACM8E6C1 A0ACM8E6C1 LOC8038053 PTHR45659:SF24 HOMEOBOX PROTEIN HOX HOMEOTIC PROTEIN ANTENNAPEDIA-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;multicellular organism development#GO:0007275;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120838615|UniProtKB=A0ACM8EJL0 A0ACM8EJL0 LOC120838615 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834131|UniProtKB=A0ACM8FPI0 A0ACM8FPI0 LOC121834131 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC8033340|UniProtKB=A0ACM8F6I6 A0ACM8F6I6 LOC8033340 PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;peptide catabolic process#GO:0043171;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8026993|UniProtKB=A0ACM8DMW5 A0ACM8DMW5 gek PTHR22988:SF75 MYOTONIC DYSTROPHY S/T KINASE-RELATED SERINE_THREONINE-PROTEIN KINASE GENGHIS KHAN catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8053916|UniProtKB=A0ACM8DLA0 A0ACM8DLA0 MFS16 PTHR43184:SF31 MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B MAJOR FACILITATOR SUPERFAMILY TRANSPORTER 16, ISOFORM B active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;phosphate transmembrane transporter activity#GO:0005315 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transporter#PC00227 IXOSC|EnsemblGenome=LOC115332101|UniProtKB=A0ACM8EWE3 A0ACM8EWE3 LOC115332101 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;nucleobase-containing compound metabolic process#GO:0006139;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC120843825|UniProtKB=A0ACM8EWY4 A0ACM8EWY4 LOC120843825 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115309012|UniProtKB=A0ACM8DN83 A0ACM8DN83 LOC115309012 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8040206|UniProtKB=A0ACM8DKJ1 A0ACM8DKJ1 Mob2 PTHR22599:SF21 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR 2 protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;kinase activator activity#GO:0019209 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC121833531|UniProtKB=A0ACM8FMI9 A0ACM8FMI9 LOC121833531 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8051380|UniProtKB=A0ACM8DPQ8 A0ACM8DPQ8 rdx PTHR24413:SF240 SPECKLE-TYPE POZ PROTEIN PROTEIN ROADKILL enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;regulation of proteolysis#GO:0030162;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8029792|UniProtKB=A0ACM8DWV6 A0ACM8DWV6 LOC8029792 PTHR47992:SF112 PROTEIN PHOSPHATASE INTEGRIN-LINKED KINASE-ASSOCIATED SERINE_THREONINE PHOSPHATASE 2C hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 protein modifying enzyme#PC00260;protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC120849940|UniProtKB=A0ACM8F9Q0 A0ACM8F9Q0 LOC120849940 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659 primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;protein sumoylation#GO:0016925 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 IXOSC|EnsemblGenome=LOC8036439|UniProtKB=A0ACM8E0B6 A0ACM8E0B6 Polr3G PTHR15367:SF2 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC8042905|UniProtKB=A0ACM8FK68 A0ACM8FK68 LOC8042905 PTHR48024:SF67 GEO13361P1-RELATED RNA-BINDING PROTEIN 24-A-LIKE PROTEIN mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120846084|UniProtKB=A0ACM8F2E9 A0ACM8F2E9 LOC120846084 PTHR45880:SF1 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 RNA-BINDING MOTIF PROTEIN, X-LINKED 2 nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 protein-containing complex#GO:0032991;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U2 snRNP#GO:0005686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904 IXOSC|EnsemblGenome=LOC120840845|UniProtKB=A0ACM8EQ81 A0ACM8EQ81 LOC120840845 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC115313283|UniProtKB=A0ACM8EXB1 A0ACM8EXB1 LOC115313283 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115317319|UniProtKB=A0ACM8G837 A0ACM8G837 LOC115317319 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8050552|UniProtKB=A0ACM8EMI8 A0ACM8EMI8 LOC8050552 PTHR11347:SF239 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 hydrolase#PC00121;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC115328783|UniProtKB=A0ACM8FGX2 A0ACM8FGX2 LOC115328783 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121047145|UniProtKB=A0ACM8FFT5 A0ACM8FFT5 LOC121047145 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115317871|UniProtKB=A0ACM8F0X7 A0ACM8F0X7 LOC115317871 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023607|UniProtKB=A0ACM8FAE9 A0ACM8FAE9 LOC8023607 PTHR14087:SF7 THYMOCYTE NUCLEAR PROTEIN 1 THYMOCYTE NUCLEAR PROTEIN 1 IXOSC|EnsemblGenome=ISCI024497|UniProtKB=Q4PLZ3 Q4PLZ3 Tctp PTHR11991:SF23 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of metabolic process#GO:0019222;negative regulation of programmed cell death#GO:0043069;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of catabolic process#GO:0009895;negative regulation of cell communication#GO:0010648 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC120837552|UniProtKB=A0ACM8FRK4 A0ACM8FRK4 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8024934|UniProtKB=A0ACM8FJF1 A0ACM8FJF1 LOC8024934 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121836066|UniProtKB=A0ACM8FX27 A0ACM8FX27 LOC121836066 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115315504|UniProtKB=A0ACM8ERJ1 A0ACM8ERJ1 LOC120846202 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8053711|UniProtKB=A0ACM8E313 A0ACM8E313 LOC8053711 PTHR22640:SF2 STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1 STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC120836206|UniProtKB=A0ACM8EJP6 A0ACM8EJP6 LOC120838227 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8040512|UniProtKB=A0ACM8FYK7 A0ACM8FYK7 LOC8040512 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8040876|UniProtKB=A0ACM8EIH6 A0ACM8EIH6 LOC8040876 PTHR11937:SF491 ACTIN PH DOMAIN-CONTAINING PROTEIN structural constituent of cytoskeleton#GO:0005200;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cytoskeletal adaptor activity#GO:0008093;structural molecule activity#GO:0005198;protein-membrane adaptor activity#GO:0043495 establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;nuclear migration#GO:0007097;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 IXOSC|EnsemblGenome=LOC115314129|UniProtKB=A0ACM8F699 A0ACM8F699 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502;post-embryonic development#GO:0009791;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;circulatory system development#GO:0072359;heart development#GO:0007507;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8037222|UniProtKB=A0ACM8EA33 A0ACM8EA33 LOC8037222 PTHR48092:SF22 KNIRPS-RELATED PROTEIN-RELATED ESTROGEN-RELATED RECEPTOR SPLICE VARIANT transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115330152|UniProtKB=A0ACM8F2P2 A0ACM8F2P2 LOC115330152 PTHR46473:SF28 GH08155P ELRR (EXTRACELLULAR LEUCINE-RICH REPEAT) ONLY IXOSC|EnsemblGenome=LOC115318711|UniProtKB=A0ACM8F7P9 A0ACM8F7P9 LOC115318711 PTHR24377:SF1039 IP01015P-RELATED SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115315335|UniProtKB=A0ACM8DV72 A0ACM8DV72 LOC115315335 PTHR11753:SF4 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-4 COMPLEX SUBUNIT SIGMA-1 cellular process#GO:0009987;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179 intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC8031118|UniProtKB=A0ACM8DVG8 A0ACM8DVG8 LOC8031118 PTHR16002:SF4 TRANSMEMBRANE PROTEIN 248-LIKE TMEM248_TMEM219 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042437|UniProtKB=A0ACM8E1Z5 A0ACM8E1Z5 LOC8042437 PTHR10270:SF324 SOX TRANSCRIPTION FACTOR SOXNEURO, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216 head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of metabolic process#GO:0009892;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115324072|UniProtKB=A0ACM8F0A8 A0ACM8F0A8 LOC115324072 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838519|UniProtKB=A0ACM8FLQ8 A0ACM8FLQ8 LOC120838519 PTHR11475:SF147 OXIDASE/PEROXIDASE PEROXIDASIN antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC8028548|UniProtKB=A0ACM8FCD3 A0ACM8FCD3 Wdr33 PTHR22836:SF0 WD40 REPEAT PROTEIN PRE-MRNA 3' END PROCESSING PROTEIN WDR33 nucleus#GO:0005634;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8040324|UniProtKB=A0ACM8DKK2 A0ACM8DKK2 LOC8040324 PTHR31742:SF1 RPA-INTERACTING PROTEIN RPAIN RPA-INTERACTING PROTEIN protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115309437|UniProtKB=A0ACM8EKA7 A0ACM8EKA7 LOC115309437 PTHR11547:SF38 ARGININE OR CREATINE KINASE ARGININE KINASE 1-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120849359|UniProtKB=A0ACM8F6P0 A0ACM8F6P0 LOC120849359 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310131|UniProtKB=A0ACM8DPH9 A0ACM8DPH9 LOC115310131 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120845986|UniProtKB=A0ACM8F0Y8 A0ACM8F0Y8 LOC120845986 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115309076|UniProtKB=A0ACM8FDY2 A0ACM8FDY2 LOC115309076 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121836447|UniProtKB=A0ACM8FYT5 A0ACM8FYT5 LOC121836447 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8028566|UniProtKB=A0ACM8EBC7 A0ACM8EBC7 fmt PTHR12634:SF40 SIT4 YEAST -ASSOCIATING PROTEIN-RELATED FIERY MOUNTAIN, ISOFORM D enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC121838063|UniProtKB=A0ACM8G6F5 A0ACM8G6F5 LOC121838063 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8042509|UniProtKB=A0ACM8EAZ6 A0ACM8EAZ6 Socs16D PTHR10155:SF39 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING AT 16D, ISOFORM B signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC8054053|UniProtKB=A0ACM8FX43 A0ACM8FX43 LOC8054053 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115321571|UniProtKB=A0ACM8F3J5 A0ACM8F3J5 LOC115321571 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8038104|UniProtKB=A0ACM8EUI5 A0ACM8EUI5 LOC8038104 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115327354|UniProtKB=A0ACM8EI68 A0ACM8EI68 LOC115327354 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8051564|UniProtKB=A0ACM8EU37 A0ACM8EU37 LOC8051564 PTHR22752:SF16 G PROTEIN-COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 101-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120836139|UniProtKB=A0ACM8EHA3 A0ACM8EHA3 LOC120836139 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115323853|UniProtKB=A0ACM8E4Q7 A0ACM8E4Q7 LOC115323853 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8052370|UniProtKB=A0ACM8EZC0 A0ACM8EZC0 LOC8052370 PTHR45620:SF42 PDF RECEPTOR-LIKE PROTEIN-RELATED G PROTEIN-COUPLED RECEPTOR SEB-2 G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121838108|UniProtKB=A0ACM8G850 A0ACM8G850 LOC121838108 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC120840889|UniProtKB=A0ACM8EQI7 A0ACM8EQI7 LOC120840889 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837395|UniProtKB=A0ACM8G4S5 A0ACM8G4S5 LOC121837395 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8040891|UniProtKB=A0ACM8DH79 A0ACM8DH79 LOC8040891 PTHR48407:SF1 CRANIOFACIAL DEVELOPMENT PROTEIN 1 HETEROCHROMATIN-STABILIZING PROTEIN CFDP1 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325 intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 IXOSC|EnsemblGenome=LOC8053623|UniProtKB=A0ACM8E1N5 A0ACM8E1N5 Nup188 PTHR31431:SF1 NUCLEOPORIN NUP188 HOMOLOG NUCLEOPORIN NUP188 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear export#GO:0051168;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 IXOSC|EnsemblGenome=LOC121832954|UniProtKB=A0ACM8FZN2 A0ACM8FZN2 LOC121832954 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC120836469|UniProtKB=A0ACM8EF61 A0ACM8EF61 LOC120836469 PTHR46481:SF16 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 BED-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324872|UniProtKB=A0ACM8EG26 A0ACM8EG26 LOC115324872 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839304|UniProtKB=A0ACM8FZB6 A0ACM8FZB6 LOC120839304 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121047116|UniProtKB=A0ACM8FFK7 A0ACM8FFK7 LOC121047116 PTHR31569:SF7 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZSWIM1_3 RNASEH-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038696|UniProtKB=A0ACM8EDN5 A0ACM8EDN5 RpS23 PTHR11652:SF14 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8034265|UniProtKB=A0ACM8FIQ2 A0ACM8FIQ2 LOC8034265 PTHR42679:SF2 S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE S-METHYL-5'-THIOADENOSINE PHOSPHORYLASE pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;proteinogenic amino acid metabolic process#GO:0170039;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;sulfur compound metabolic process#GO:0006790;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;purine-containing compound metabolic process#GO:0072521 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 Purine metabolism#P02769>Nucleoside Phosphorylase#P03115 IXOSC|EnsemblGenome=LOC120836620|UniProtKB=A0ACM8FLX1 A0ACM8FLX1 LOC120836620 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8051122|UniProtKB=A0ACM8EI75 A0ACM8EI75 LOC8051122 PTHR12560:SF0 LONGEVITY ASSURANCE FACTOR 1 LAG1 LD18904P acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;ceramide metabolic process#GO:0006672;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120838250|UniProtKB=A0ACM8EJH8 A0ACM8EJH8 LOC120838250 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041609|UniProtKB=A0ACM8EBK3 A0ACM8EBK3 LOC8041609 PTHR11668:SF530 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE PP-Y-RELATED catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC121835304|UniProtKB=A0ACM8FSC2 A0ACM8FSC2 LOC121835304 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120841039|UniProtKB=A0ACM8ERT6 A0ACM8ERT6 LOC120841039 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120841041|UniProtKB=A0ACM8EQN6 A0ACM8EQN6 LOC120841041 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8053944|UniProtKB=A0ACM8ECB1 A0ACM8ECB1 Swim PTHR12411:SF1062 CYSTEINE PROTEASE FAMILY C1-RELATED SI:DKEY-158B13.1 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC120848987|UniProtKB=A0ACM8F6T7 A0ACM8F6T7 LOC120848987 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC8037721|UniProtKB=A0ACM8DNQ8 A0ACM8DNQ8 PTHR43201:SF8 ACYL-COA SYNTHETASE ACYL-COA SYNTHETASE FAMILY MEMBER 3 catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843132|UniProtKB=A0ACM8EVD8 A0ACM8EVD8 LOC120843132 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8033285|UniProtKB=A0ACM8E8H5 A0ACM8E8H5 LOC8033285 PTHR11346:SF191 GALECTIN GALECTIN carbohydrate binding#GO:0030246;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8033335|UniProtKB=A0ACM8E7C4 A0ACM8E7C4 LOC8033335 PTHR48051:SF47 FAMILY NOT NAMED RING-TYPE DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8027374|UniProtKB=A0ACM8EE84 A0ACM8EE84 LOC8027374 PTHR11267:SF195 T-BOX PROTEIN-RELATED OPTOMOTOR-BLIND-RELATED-GENE-1, ISOFORM A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of RNA metabolic process#GO:0051252;cell fate commitment#GO:0045165;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;cell fate specification#GO:0001708;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 IXOSC|EnsemblGenome=LOC120840893|UniProtKB=A0ACM8FEW1 A0ACM8FEW1 LOC120840893 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115309209|UniProtKB=A0ACM8F9V7 A0ACM8F9V7 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8041721|UniProtKB=A0ACM8FSZ8 A0ACM8FSZ8 LOC8041721 PTHR45080:SF45 CONTACTIN 5 IP11255P signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043 axon#GO:0030424;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;membrane#GO:0016020;cell periphery#GO:0071944;cell body#GO:0044297;neuron projection#GO:0043005 IXOSC|EnsemblGenome=LOC115323188|UniProtKB=A0ACM8E2R3 A0ACM8E2R3 LOC115323188 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;A2-type glycerophospholipase activity#GO:0004623 IXOSC|EnsemblGenome=LOC120849016|UniProtKB=A0ACM8F7S7 A0ACM8F7S7 LOC120849016 PTHR22950:SF244 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID TRANSPORTER 9 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosomal membrane#GO:0005765;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852 secondary carrier transporter#PC00258;amino acid transporter#PC00046 IXOSC|EnsemblGenome=LOC120848586|UniProtKB=A0ACM8F5X2 A0ACM8F5X2 PTHR12630:SF1 N-LINKED OLIGOSACCHARIDE PROCESSING GLUCOSIDASE 2 SUBUNIT BETA-RELATED biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8040803|UniProtKB=A0ACM8EEI4 A0ACM8EEI4 Ino80 PTHR45685:SF2 HELICASE SRCAP-RELATED CHROMATIN-REMODELING ATPASE INO80 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;histone binding#GO:0042393;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular response to stress#GO:0033554;response to stimulus#GO:0050896;chromatin remodeling#GO:0006338;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;chromatin organization#GO:0006325;response to stress#GO:0006950;cellular process#GO:0009987 intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;Ino80 complex#GO:0031011;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 Wnt signaling pathway#P00057>SWI/SNF#P01435 IXOSC|EnsemblGenome=LOC8030397|UniProtKB=A0ACM8E6P2 A0ACM8E6P2 LOC8030397 PTHR43020:SF2 CDK5 REGULATORY SUBUNIT-ASSOCIATED PROTEIN 1 MITOCHONDRIAL TRNA METHYLTHIOTRANSFERASE CDK5RAP1 binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536;catalytic activity, acting on a tRNA#GO:0140101;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;mitochondrial RNA metabolic process#GO:0000959;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA modification#GO:1900864;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121838150|UniProtKB=A0ACM8G6L4 A0ACM8G6L4 LOC121838150 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8030063|UniProtKB=A0ACM8EEJ4 A0ACM8EEJ4 PTHR23185:SF0 PROTEIN VIRILIZER HOMOLOG PROTEIN VIRILIZER HOMOLOG cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;methyltransferase complex#GO:0034708;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC8041800|UniProtKB=A0ACM8E6M4 A0ACM8E6M4 LOC8041800 PTHR45858:SF5 FERM DOMAIN CONTAINING PROTEIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 IXOSC|EnsemblGenome=LOC8037647|UniProtKB=A0ACM8DI81 A0ACM8DI81 PTHR19856:SF8 WD-REPEATCONTAINING PROTEIN WDR1 WD REPEAT-CONTAINING PROTEIN 1 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 developmental process#GO:0032502;cellular developmental process#GO:0048869;actin filament organization#GO:0007015;actin polymerization or depolymerization#GO:0008154;protein depolymerization#GO:0051261;cellular component assembly involved in morphogenesis#GO:0010927;organelle assembly#GO:0070925;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435;muscle cell development#GO:0055001;muscle cell differentiation#GO:0042692;myofibril assembly#GO:0030239;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;protein-containing complex disassembly#GO:0032984;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;protein-containing complex organization#GO:0043933;anatomical structure formation involved in morphogenesis#GO:0048646;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;actin filament depolymerization#GO:0030042;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;animal gross anatomical part developmental process#GO:0160108;cellular component disassembly#GO:0022411;striated muscle cell development#GO:0055002;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;cell development#GO:0048468;actomyosin structure organization#GO:0031032 cell periphery#GO:0071944;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC8032314|UniProtKB=A0ACM8FX87 A0ACM8FX87 hh PTHR11889:SF86 HEDGEHOG PROTEIN HEDGEHOG calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;signaling receptor binding#GO:0005102;cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872 biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;cell fate specification#GO:0001708;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;smoothened signaling pathway#GO:0007224;cell fate commitment#GO:0045165;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Hedgehog signaling pathway#P00025>Hedgehog#P00688 IXOSC|EnsemblGenome=LOC8030283|UniProtKB=A0ACM8FR57 A0ACM8FR57 LOC8030283 PTHR22852:SF2 LETHAL 2 DENTICLELESS PROTEIN RETINOIC ACID-REGULATED NUCLEAR MATRIX-ASSOCIATED PROTEIN DENTICLELESS PROTEIN HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of cellular process#GO:0048523;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;protein metabolic process#GO:0019538;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;intracellular signal transduction#GO:0035556;primary metabolic process#GO:0044238;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;proteasomal protein catabolic process#GO:0010498;regulation of cell cycle process#GO:0010564;modification-dependent macromolecule catabolic process#GO:0043632;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;regulation of mitotic cell cycle phase transition#GO:1901990;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8029890|UniProtKB=A0ACM8DJ30 A0ACM8DJ30 Nipped-B PTHR21704:SF18 NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED NIPPED-B PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization#GO:0016043;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;mitotic sister chromatid cohesion#GO:0007064;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;DNA damage response#GO:0006974;DNA repair#GO:0006281;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;localization#GO:0051179;sister chromatid cohesion#GO:0007062;recombinational repair#GO:0000725 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8040146|UniProtKB=A0ACM8FH91 A0ACM8FH91 LOC8040146 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120840034|UniProtKB=A0ACM8EP78 A0ACM8EP78 LOC120840034 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC115327590|UniProtKB=A0ACM8EX68 A0ACM8EX68 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115326691|UniProtKB=A0ACM8E7Q4 A0ACM8E7Q4 LOC115326691 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC121835501|UniProtKB=A0ACM8FUD6 A0ACM8FUD6 LOC121835501 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120847538|UniProtKB=A0ACM8F482 A0ACM8F482 LOC120847538 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8024163|UniProtKB=A0ACM8DI08 A0ACM8DI08 aph-1 PTHR12889:SF8 GAMMA-SECRETASE SUBUNIT APH-1 GAMMA-SECRETASE SUBUNIT APH-1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 proteolysis#GO:0006508;cell communication#GO:0007154;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;signal transduction#GO:0007165;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;biological regulation#GO:0065007;protein maturation#GO:0051604;gene expression#GO:0010467 plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>Aph-1#P00091;Notch signaling pathway#P00045>Aph-1#P01109;Alzheimer disease-presenilin pathway#P00004>Aph-1#P00170 IXOSC|EnsemblGenome=LOC120844706|UniProtKB=A0ACM8G7Z0 A0ACM8G7Z0 LOC120844706 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8027636|UniProtKB=A0ACM8E9F0 A0ACM8E9F0 LOC8027636 PTHR15863:SF2 MRN COMPLEX-INTERACTING PROTEIN MRN COMPLEX-INTERACTING PROTEIN chromatin binding#GO:0003682;binding#GO:0005488 regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA damage checkpoint signaling#GO:0000077;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;mitotic cell cycle process#GO:1903047;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;cellular response to stress#GO:0033554;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8051284|UniProtKB=A0ACM8FJA0 A0ACM8FJA0 LOC8051284 PTHR35555:SF4 ENDONUCLEASE-REVERSE TRANSCRIPTASE TRANSMEMBRANE PROTEIN IXOSC|EnsemblGenome=LOC120849788|UniProtKB=A0ACM8F8R7 A0ACM8F8R7 LOC120849788 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8051029|UniProtKB=A0ACM8E9Y2 A0ACM8E9Y2 LOC8051029 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 IXOSC|EnsemblGenome=LOC8043916|UniProtKB=A0ACM8DVG2 A0ACM8DVG2 LOC8043916 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8040689|UniProtKB=A0ACM8FAD3 A0ACM8FAD3 LOC8040689 PTHR46393:SF7 SUSHI DOMAIN-CONTAINING PROTEIN C3_C5 CONVERTASE IXOSC|EnsemblGenome=LOC121834198|UniProtKB=A0ACM8FQE1 A0ACM8FQE1 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115331482|UniProtKB=A0ACM8F7H1 A0ACM8F7H1 LOC115331482 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8025833|UniProtKB=A0ACM8DVJ3 A0ACM8DVJ3 LOC8025833 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8029709|UniProtKB=A0ACM8DIN5 A0ACM8DIN5 LOC8029709 PTHR10742:SF423 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 1A chromatin binding#GO:0003682;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;nucleoside phosphate binding#GO:1901265;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;protein demethylase activity#GO:0140457;heterocyclic compound binding#GO:1901363;demethylase activity#GO:0032451;histone demethylase activity#GO:0032452 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 oxidase#PC00175 IXOSC|EnsemblGenome=LOC115320173|UniProtKB=A0ACM8E101 A0ACM8E101 LOC115320173 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035070|UniProtKB=A0ACM8E9C0 A0ACM8E9C0 LOC8035070 PTHR10202:SF27 PRESENILIN PRESENILIN HOMOLOG catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein maturation#GO:0051604;gene expression#GO:0010467;membrane protein ectodomain proteolysis#GO:0006509;biological regulation#GO:0065007;biosynthetic process#GO:0009058;monoatomic ion homeostasis#GO:0050801;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;Notch signaling pathway#GO:0007219;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;homeostatic process#GO:0042592;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;cell communication#GO:0007154;calcium ion homeostasis#GO:0055074;proteolysis#GO:0006508;inorganic ion homeostasis#GO:0098771 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;catalytic complex#GO:1902494 protease#PC00190;aspartic protease#PC00053 Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Notch signaling pathway#P00045>Presenilin#P01110 IXOSC|EnsemblGenome=LOC120840686|UniProtKB=A0ACM8G275 A0ACM8G275 LOC120840686 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8041829|UniProtKB=A0ACM8DKS9 A0ACM8DKS9 Tudor-SN PTHR12302:SF2 EBNA2 BINDING PROTEIN P100 STAPHYLOCOCCAL NUCLEASE DOMAIN-CONTAINING PROTEIN 1 RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115320942|UniProtKB=A0ACM8F0L6 A0ACM8F0L6 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324409|UniProtKB=A0ACM8EXA4 A0ACM8EXA4 LOC115324409 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328897|UniProtKB=A0ACM8EG12 A0ACM8EG12 LOC115328897 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115322567|UniProtKB=A0ACM8E281 A0ACM8E281 hppy PTHR48012:SF18 STERILE20-LIKE KINASE, ISOFORM B-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Apoptosis signaling pathway#P00006>GCKR#P00311;Apoptosis signaling pathway#P00006>GCK#P00268 IXOSC|EnsemblGenome=LOC121833674|UniProtKB=A0ACM8FKT3 A0ACM8FKT3 LOC121833674 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8029893|UniProtKB=A0ACM8DJ20 A0ACM8DJ20 LOC8029893 PTHR23389:SF21 CHROMOSOME TRANSMISSION FIDELITY FACTOR 18 ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 5 binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120838237|UniProtKB=A0ACM8FPP1 A0ACM8FPP1 LOC120838237 PTHR11003:SF338 POTASSIUM CHANNEL, SUBFAMILY K POTASSIUM CHANNEL SUBFAMILY K MEMBER 16-LIKE monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;outward rectifier potassium channel activity#GO:0015271;potassium channel activity#GO:0005267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8024969|UniProtKB=A0ACM8FVC0 A0ACM8FVC0 LOC8024969 PTHR13817:SF172 TITIN FASCICLIN-2-LIKE PROTEIN structural protein#PC00211 Axon guidance mediated by Slit/Robo#P00008>Robo#P00348 IXOSC|EnsemblGenome=LOC121835997|UniProtKB=A0ACM8FWP5 A0ACM8FWP5 LOC121835997 PTHR35000:SF1 MUCIN MUC17, PUTATIVE-RELATED-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120837102|UniProtKB=A0ACM8FBE9 A0ACM8FBE9 LOC120837102 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024904|UniProtKB=A0ACM8DRE5 A0ACM8DRE5 PTHR20930:SF10 OVARIAN CARCINOMA ANTIGEN CA125-RELATED PROTEIN ILRUN regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;transport#GO:0006810;vacuolar transport#GO:0007034;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;macroautophagy#GO:0016236;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;macromolecule localization#GO:0033036;localization#GO:0051179;protein localization to vacuole#GO:0072665;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of multicellular organismal process#GO:0051241;regulation of localization#GO:0032879;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;regulation of multicellular organismal process#GO:0051239;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;autophagy#GO:0006914;protein targeting to vacuole#GO:0006623;negative regulation of macromolecule biosynthetic process#GO:0010558;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;regulation of protein localization#GO:0032880;cellular localization#GO:0051641;negative regulation of metabolic process#GO:0009892;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cytosol#GO:0005829;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120836773|UniProtKB=A0ACM8EGD3 A0ACM8EGD3 LOC120836773 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121047385|UniProtKB=A0ACM8FES6 A0ACM8FES6 LOC121047385 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051449|UniProtKB=A0ACM8F4G0 A0ACM8F4G0 LOC8051449 PTHR12689:SF4 A1 CISTRON SPLICING FACTOR AAR2-RELATED PROTEIN AAR2 HOMOLOG RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8052340|UniProtKB=A0ACM8DM50 A0ACM8DM50 LOC8052340 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8035292|UniProtKB=A0ACM8EP54 A0ACM8EP54 LOC8035292 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8027107|UniProtKB=A0ACM8DIP2 A0ACM8DIP2 LOC8027107 PTHR19375:SF582 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK 70 KDA PROTEIN COGNATE 1-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC8032377|UniProtKB=A0ACM8DYH1 A0ACM8DYH1 RpS11 PTHR10744:SF9 40S RIBOSOMAL PROTEIN S11 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US17 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8024917|UniProtKB=A0ACM8DRE2 A0ACM8DRE2 Ythdf PTHR12357:SF140 YTH YT521-B HOMOLOGY DOMAIN-CONTAINING YTH DOMAIN-CONTAINING FAMILY PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;protein-RNA adaptor activity#GO:0140517;RNA binding#GO:0003723 positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;positive regulation of mRNA catabolic process#GO:0061014;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120846242|UniProtKB=A0ACM8F2S5 A0ACM8F2S5 LOC120846243 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8053006|UniProtKB=A0ACM8DWU3 A0ACM8DWU3 LOC8053006 PTHR19134:SF544 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 protein modifying enzyme#PC00260;protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC121837799|UniProtKB=A0ACM8G6H5 A0ACM8G6H5 LOC121837799 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8028155|UniProtKB=A0ACM8DJL6 A0ACM8DJL6 PTHR11158:SF17 MSF1/PX19 RELATED PROTEIN SLOWMO lipid transfer activity#GO:0120013;phospholipid transfer activity#GO:0120014;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;organophosphate ester transport#GO:0015748;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;establishment of localization#GO:0051234;localization#GO:0051179 mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mitochondrial intermembrane space#GO:0005758;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120836077|UniProtKB=A0ACM8EVV5 A0ACM8EVV5 LOC120836077 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034969|UniProtKB=A0ACM8DJL9 A0ACM8DJL9 LOC8034969 PTHR14248:SF40 CYCLIN Y, ISOFORM A CYCLIN Y, ISOFORM A kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC115319652|UniProtKB=A0ACM8EHG1 A0ACM8EHG1 LOC115319652 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026470|UniProtKB=A0ACM8DUC6 A0ACM8DUC6 LOC8026470 PTHR43329:SF4 EPOXIDE HYDROLASE SERINE HYDROLASE-LIKE PROTEIN-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8034677|UniProtKB=A0ACM8FMC0 A0ACM8FMC0 LOC8034677 PTHR15592:SF18 MATRIN 3/NUCLEAR PROTEIN 220-RELATED SMOOTH, ISOFORM T RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8034838|UniProtKB=A0ACM8DR38 A0ACM8DR38 LOC8034838 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364 glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC8035955|UniProtKB=A0ACM8G603 A0ACM8G603 LOC8035955 PTHR20923:SF1 BAT4 PROTEIN-RELATED G PATCH DOMAIN AND ANKYRIN REPEAT-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC120849456|UniProtKB=A0ACM8F6U5 A0ACM8F6U5 LOC120849456 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032095|UniProtKB=A0ACM8E765 A0ACM8E765 LOC8032095 PTHR47327:SF23 FI18240P1-RELATED FI17836P1 anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856 IXOSC|EnsemblGenome=LOC8024930|UniProtKB=A0ACM8F7F5 A0ACM8F7F5 LOC8024930 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115332506|UniProtKB=A0ACM8EZ66 A0ACM8EZ66 LOC115332506 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115312001|UniProtKB=A0ACM8EP67 A0ACM8EP67 LOC115312001 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8034369|UniProtKB=A0ACM8DPL9 A0ACM8DPL9 PTHR43220:SF21 FAMILY NOT NAMED TRANSMEMBRANE PROTEIN 41A IXOSC|EnsemblGenome=LOC8031122|UniProtKB=A0ACM8EN43 A0ACM8EN43 LOC8031122 PTHR13865:SF28 TIGHT JUNCTION PROTEIN POLYCHAETOID, ISOFORM O protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to cell junction#GO:1902414;cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216;cell junction organization#GO:0034330;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;macromolecule localization#GO:0033036;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;plasma membrane#GO:0005886;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;tight junction#GO:0070160;cell junction#GO:0030054;anchoring junction#GO:0070161;apical junction complex#GO:0043296 cell junction protein#PC00070;tight junction#PC00214 IXOSC|EnsemblGenome=LOC115311315|UniProtKB=A0ACM8FHH9 A0ACM8FHH9 LOC115311315 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120849316|UniProtKB=A0ACM8F7Y2 A0ACM8F7Y2 LOC120849316 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043832|UniProtKB=A0ACM8G2E2 A0ACM8G2E2 LOC8043832 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8051835|UniProtKB=A0ACM8G722 A0ACM8G722 LOC8051835 PTHR10270:SF338 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14 transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;system development#GO:0048731;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182;animal organ development#GO:0048513;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;head development#GO:0060322;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 IXOSC|EnsemblGenome=LOC115325865|UniProtKB=A0ACM8EIB6 A0ACM8EIB6 LOC115325865 PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;DNA-templated transcription initiation#GO:0006352;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription#GO:0006351 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;Huntington disease#P00029>TBP#P00779 IXOSC|EnsemblGenome=LOC8025683|UniProtKB=A0ACM8F1C5 A0ACM8F1C5 LOC8025683 PTHR11243:SF38 GROWTH FACTOR RECEPTOR-BOUND PROTEIN GROWTH FACTOR RECEPTOR-BOUND PROTEIN 14-LIKE ISOFORM X1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8026619|UniProtKB=A0ACM8EHP6 A0ACM8EHP6 LOC8026619 PTHR11056:SF0 HOMOGENTISATE 1,2-DIOXYGENASE HOMOGENTISATE 1,2-DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;catalytic activity#GO:0003824 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053676|UniProtKB=A0ACM8E3A7 A0ACM8E3A7 BCAS2 PTHR13296:SF0 BCAS2 PROTEIN PRE-MRNA-SPLICING FACTOR SPF27 mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;Prp19 complex#GO:0000974;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120836883|UniProtKB=A0ACM8FN76 A0ACM8FN76 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115331435|UniProtKB=A0ACM8F7V1 A0ACM8F7V1 LOC115331435 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8042408|UniProtKB=A0ACM8ESC8 A0ACM8ESC8 LOC8042408 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC chromatin binding#GO:0003682;binding#GO:0005488 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC121836309|UniProtKB=A0ACM8FY88 A0ACM8FY88 LOC121836309 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120838357|UniProtKB=A0ACM8EJR7 A0ACM8EJR7 LOC120838357 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8038476|UniProtKB=A0ACM8F9Q8 A0ACM8F9Q8 LOC8038476 PTHR11552:SF233 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI02019P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115332001|UniProtKB=A0ACM8FYA4 A0ACM8FYA4 LOC115332001 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837327|UniProtKB=A0ACM8G473 A0ACM8G473 LOC121837327 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120845841|UniProtKB=A0ACM8FHZ6 A0ACM8FHZ6 PTHR19303:SF57 TRANSPOSON POGO TRANSPOSABLE ELEMENT WITH KRAB DOMAIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052990|UniProtKB=A0ACM8DZJ0 A0ACM8DZJ0 LOC8052990 PTHR13236:SF0 DYNEIN 2 LIGHT INTERMEDIATE CHAIN, ISOFORM 2 CYTOPLASMIC DYNEIN 2 LIGHT INTERMEDIATE CHAIN 1 protein binding#GO:0005515;binding#GO:0005488 plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;intraciliary transport involved in cilium assembly#GO:0035735;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;intraciliary retrograde transport#GO:0035721;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ciliary plasm#GO:0097014;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC115314850|UniProtKB=A0ACM8EW82 A0ACM8EW82 LOC115314850 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121837947|UniProtKB=A0ACM8G6W1 A0ACM8G6W1 LOC121837947 PTHR23248:SF9 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE intramembrane lipid carrier activity#GO:0140303;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;phospholipid transport#GO:0015914;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;membrane organization#GO:0061024;macromolecule localization#GO:0033036;cellular process#GO:0009987;localization#GO:0051179;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;cellular component organization#GO:0016043 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC121836386|UniProtKB=A0ACM8FZH3 A0ACM8FZH3 LOC121836386 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120837879|UniProtKB=A0ACM8EIG4 A0ACM8EIG4 LOC120837879 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023377|UniProtKB=A0ACM8DGW1 A0ACM8DGW1 LOC8023377 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8035183|UniProtKB=A0ACM8E7U6 A0ACM8E7U6 Dmtn PTHR17613:SF14 CEREBRAL PROTEIN-11-RELATED DEMENTIN, ISOFORM H endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115311317|UniProtKB=A0ACM8F8N6 A0ACM8F8N6 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026382|UniProtKB=A0ACM8E0U1 A0ACM8E0U1 LOC8026382 PTHR10779:SF31 DYNEIN LIGHT CHAIN ROADBLOCK DYNEIN LIGHT CHAIN ROADBLOCK-TYPE 2 protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;microtubule-based movement#GO:0007018;cellular process#GO:0009987 microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8035803|UniProtKB=A0ACM8EFQ8 A0ACM8EFQ8 LOC8035803 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121833781|UniProtKB=A0ACM8FN08 A0ACM8FN08 LOC121833781 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC8028063|UniProtKB=A0ACM8DJK3 A0ACM8DJK3 LOC8028063 PTHR11909:SF428 CASEIN KINASE-RELATED DISCS OVERGROWN PROTEIN KINASE-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of canonical Wnt signaling pathway#GO:0090263;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cell communication#GO:0007154;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of Wnt signaling pathway#GO:0030111;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of signaling#GO:0023056;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Hedgehog signaling pathway#P00025>Casein kinase I#P00681;Circadian clock system#P00015>Casein kinase I#P00502;Parkinson disease#P00049>Casein kinase I#P01242 IXOSC|EnsemblGenome=LOC120845849|UniProtKB=A0ACM8F0Z5 A0ACM8F0Z5 LOC120845850 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316466|UniProtKB=A0ACM8F2X6 A0ACM8F2X6 LOC115316466 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115332410|UniProtKB=A0ACM8EEJ3 A0ACM8EEJ3 LOC115332410 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115326204|UniProtKB=A0ACM8E6M3 A0ACM8E6M3 LOC115326204 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of protein metabolic process#GO:0051246;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA metabolic process#GO:0016070;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739 hydrolase#PC00121;deaminase#PC00088;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115326801|UniProtKB=A0ACM8F0B7 A0ACM8F0B7 LOC115326801 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120847716|UniProtKB=A0ACM8FS55 A0ACM8FS55 LOC120847716 PTHR47535:SF1 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G MUSCLE-SPECIFIC PROTEIN 300 KDA protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 nuclear migration#GO:0007097;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of organelle localization#GO:0051656;organelle localization#GO:0051640;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 nuclear protein-containing complex#GO:0140513;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane#GO:0016020;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796 IXOSC|EnsemblGenome=LOC120840397|UniProtKB=A0ACM8EP17 A0ACM8EP17 LOC120840397 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319549|UniProtKB=A0ACM8F414 A0ACM8F414 LOC115319549 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326099|UniProtKB=A0ACM8FL67 A0ACM8FL67 LOC115326099 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC121834697|UniProtKB=A0ACM8FRM6 A0ACM8FRM6 PTHR19282:SF431 TETRASPANIN TETRASPANIN 26A, ISOFORM B membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121835676|UniProtKB=A0ACM8FVB9 A0ACM8FVB9 LOC121835676 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115314054|UniProtKB=A0ACM8F3N6 A0ACM8F3N6 LOC115314054 PTHR10924:SF4 MAJOR FACILITATOR SUPERFAMILY PROTEIN-RELATED CHOLINE_ETHANOLAMINE TRANSPORTER FLVCR1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;heme binding#GO:0020037;binding#GO:0005488;tetrapyrrole binding#GO:0046906 nitrogen compound transport#GO:0071705;metal ion transport#GO:0030001;iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;transport#GO:0006810;iron coordination entity transport#GO:1901678;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8034203|UniProtKB=A0ACM8FTG8 A0ACM8FTG8 LOC8034203 PTHR14049:SF9 LEPRECAN 1 PROCOLLAGEN-PROLINE 3-DIOXYGENASE extracellular matrix glycoprotein#PC00100 IXOSC|EnsemblGenome=LOC120846309|UniProtKB=A0ACM8F203 A0ACM8F203 LOC120846309 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310010|UniProtKB=A0ACM8FWZ2 A0ACM8FWZ2 LOC115310010 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8026788|UniProtKB=A0ACM8DIB7 A0ACM8DIB7 LOC8026788 PTHR10760:SF18 TORSIN LD13476P-RELATED cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;cellular response to misfolded protein#GO:0071218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to misfolded protein#GO:0051788;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896 chaperone#PC00072 Parkinson disease#P00049>Torsin A#P01221 IXOSC|EnsemblGenome=LOC8042405|UniProtKB=A0ACM8DSV4 A0ACM8DSV4 Pdk PTHR11947:SF3 PYRUVATE DEHYDROGENASE KINASE [PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of carbohydrate metabolic process#GO:0006109;regulation of lipid metabolic process#GO:0019216;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8043255|UniProtKB=A0ACM8E8D9 A0ACM8E8D9 LOC8043255 PTHR43143:SF1 METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY SERINE_THREONINE-PROTEIN PHOSPHATASE CPPED1 protein phosphatase#PC00195;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115312903|UniProtKB=A0ACM8G2P5 A0ACM8G2P5 LOC115312903 PTHR33776:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325466|UniProtKB=A0ACM8FQ27 A0ACM8FQ27 LOC115325466 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8039561|UniProtKB=A0ACM8DZD4 A0ACM8DZD4 LOC8039561 PTHR11679:SF92 VESICLE PROTEIN SORTING-ASSOCIATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 33B intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192 vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;lytic vacuole#GO:0000323;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC120846761|UniProtKB=A0ACM8F373 A0ACM8F373 LOC120846761 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8024887|UniProtKB=A0ACM8EAL0 A0ACM8EAL0 LOC8024887 PTHR16056:SF36 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN TETRATRICOPEPTIDE REPEAT PROTEIN microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;spindle#GO:0005819;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;mitotic spindle pole#GO:0097431;microtubule#GO:0005874;spindle microtubule#GO:0005876;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;spindle pole#GO:0000922;mitochondrion#GO:0005739 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC115328335|UniProtKB=A0ACM8FRZ7 A0ACM8FRZ7 LOC115328335 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029195|UniProtKB=A0ACM8G4Z6 A0ACM8G4Z6 LOC8029195 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8025771|UniProtKB=A0ACM8DQI0 A0ACM8DQI0 Josd PTHR13291:SF0 JOSEPHIN 1, 2 JOSEPHIN-LIKE PROTEIN deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 protein modifying enzyme#PC00260;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8026441|UniProtKB=A0ACM8DSD0 A0ACM8DSD0 LOC8026441 PTHR12111:SF2 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2B-RELATED ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120849459|UniProtKB=A0ACM8F858 A0ACM8F858 LOC120849459 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115328888|UniProtKB=A0ACM8G0S7 A0ACM8G0S7 LOC115328888 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115315965|UniProtKB=A0ACM8ERW9 A0ACM8ERW9 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8036197|UniProtKB=A0ACM8EAH6 A0ACM8EAH6 kz PTHR18934:SF99 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX37-RELATED catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC115309116|UniProtKB=A0ACM8F2C8 A0ACM8F2C8 LOC115309116 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115324638|UniProtKB=A0ACM8FJ19 A0ACM8FJ19 LOC115324638 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8052380|UniProtKB=A0ACM8E292 A0ACM8E292 LOC8052380 PTHR11773:SF1 GLYCINE DEHYDROGENASE, DECARBOXYLATING GLYCINE DEHYDROGENASE (DECARBOXYLATING), MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115326249|UniProtKB=A0ACM8E5R3 A0ACM8E5R3 LOC115326249 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328087|UniProtKB=A0ACM8F0P5 A0ACM8F0P5 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040944|UniProtKB=A0ACM8G7I1 A0ACM8G7I1 LOC8040944 PTHR12143:SF45 PEPTIDE N-GLYCANASE PNGASE -RELATED PEPTIDE-N(4)-(N-ACETYL-BETA-GLUCOSAMINYL)ASPARAGINE AMIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;positive regulation of BMP signaling pathway#GO:0030513;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;glycoprotein metabolic process#GO:0009100;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;carbohydrate derivative metabolic process#GO:1901135;positive regulation of biological process#GO:0048518 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 Oxidative stress response#P00046>TRX#P01122;Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 IXOSC|EnsemblGenome=LOC8052600|UniProtKB=A0ACM8DZU0 A0ACM8DZU0 LOC8052600 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8037496|UniProtKB=A0ACM8EQT0 A0ACM8EQT0 LOC8037496 PTHR28583:SF1 ACID AMIDASE ACID CERAMIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115321848|UniProtKB=A0ACM8E229 A0ACM8E229 LOC115321848 PTHR21433:SF0 TRANSMEMBRANE PROTEIN INDUCED BY TUMOR NECROSIS FACTOR ALPHA TRANSMEMBRANE PROTEIN 120 HOMOLOG intracellular organelle#GO:0043229;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;nucleus#GO:0005634;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;membrane#GO:0016020;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC115322285|UniProtKB=A0ACM8E1X8 A0ACM8E1X8 LOC115322285 PTHR10643:SF2 KINETOCHORE PROTEIN NDC80 KINETOCHORE PROTEIN NDC80 HOMOLOG organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;attachment of spindle microtubules to kinetochore#GO:0008608;cellular process#GO:0009987;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cell cycle#GO:0007049;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;mitotic metaphase chromosome alignment#GO:0007080;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;nuclear division#GO:0000280;organelle localization#GO:0051640;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;localization#GO:0051179;organelle fission#GO:0048285 intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC115314296|UniProtKB=A0ACM8EUY3 A0ACM8EUY3 LOC115314296 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115312900|UniProtKB=A0ACM8G5Q7 A0ACM8G5Q7 LOC115312900 PTHR45688:SF3 FAMILY NOT NAMED ALANINE--GLYOXYLATE AMINOTRANSFERASE 2, MITOCHONDRIAL IXOSC|EnsemblGenome=LOC8041513|UniProtKB=A0ACM8DUS2 A0ACM8DUS2 Khc-73 PTHR24115:SF997 KINESIN-RELATED KINESIN HEAVY CHAIN 73, ISOFORM E microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;tubulin binding#GO:0015631;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774 microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874 microtubule binding motor protein#PC00156;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC120850890|UniProtKB=A0ACM8F9Y9 A0ACM8F9Y9 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837126|UniProtKB=A0ACM8G2C5 A0ACM8G2C5 LOC121837126 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8038934|UniProtKB=A0ACM8E411 A0ACM8E411 LOC8038934 PTHR24270:SF68 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED LD11117P-RELATED receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transfer/carrier protein#PC00219;apolipoprotein#PC00052 IXOSC|EnsemblGenome=LOC8024155|UniProtKB=A0ACM8DTA6 A0ACM8DTA6 abs PTHR47958:SF103 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX41-RELATED ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8037404|UniProtKB=A0ACM8DI42 A0ACM8DI42 LOC8037404 PTHR21431:SF0 PREFOLDIN SUBUNIT 6 PREFOLDIN SUBUNIT 6 protein binding#GO:0005515;protein-folding chaperone binding#GO:0051087;binding#GO:0005488 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121837465|UniProtKB=A0ACM8G4M6 A0ACM8G4M6 LOC121837465 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8037523|UniProtKB=A0ACM8DXR5 A0ACM8DXR5 ldbr PTHR12849:SF0 RNA LARIAT DEBRANCHING ENZYME LARIAT DEBRANCHING ENZYME endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;catabolic process#GO:0009056;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound catabolic process#GO:0034655;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC121835159|UniProtKB=A0ACM8FRQ7 A0ACM8FRQ7 LOC121835159 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848550|UniProtKB=A0ACM8F534 A0ACM8F534 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043075|UniProtKB=A0ACM8FHQ1 A0ACM8FHQ1 LOC8043075 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC115327423|UniProtKB=A0ACM8FU19 A0ACM8FU19 LOC115327423 PTHR23077:SF27 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG A hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8023895|UniProtKB=A0ACM8E8B4 A0ACM8E8B4 LOC8023895 PTHR13161:SF4 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT CLK4-ASSOCIATING SERINE_ARGININE RICH PROTEIN RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115323726|UniProtKB=A0ACM8FBS5 A0ACM8FBS5 LOC115323726 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030934|UniProtKB=A0ACM8DSU9 A0ACM8DSU9 LOC8030934 PTHR22655:SF2 ATP-DEPENDENT RNA HELICASE TDRD12-RELATED ATP-DEPENDENT RNA HELICASE TDRD12-RELATED regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;piRNA processing#GO:0034587;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115320258|UniProtKB=A0ACM8F0Y1 A0ACM8F0Y1 LOC115320258 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8038095|UniProtKB=A0ACM8FET5 A0ACM8FET5 LOC8038095 PTHR10290:SF3 DNA TOPOISOMERASE I DNA TOPOISOMERASE 1 DNA topoisomerase#PC00017;DNA metabolism protein#PC00009 DNA replication#P00017>DNA Topisomerase#P00536;DNA replication#P00017>Top#P00530 IXOSC|EnsemblGenome=LOC8052611|UniProtKB=A0ACM8DLY5 A0ACM8DLY5 LOC8052611 PTHR24258:SF147 SERINE PROTEASE-RELATED FI16631P1-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120847550|UniProtKB=A0ACM8F3F2 A0ACM8F3F2 LOC120847550 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845982|UniProtKB=A0ACM8F0H5 A0ACM8F0H5 LOC120845982 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120841760|UniProtKB=A0ACM8ES12 A0ACM8ES12 LOC120841760 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038248|UniProtKB=A0ACM8E949 A0ACM8E949 LOC8038248 PTHR13246:SF1 ENDO BETA N-ACETYLGLUCOSAMINIDASE CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 deaminase#PC00088;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120841202|UniProtKB=A0ACM8ER19 A0ACM8ER19 LOC120841202 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8043498|UniProtKB=A0ACM8DL55 A0ACM8DL55 Sec61beta PTHR13509:SF26 SEC61 SUBUNIT BETA PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;rough endoplasmic reticulum membrane#GO:0030867;rough endoplasmic reticulum#GO:0005791;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121833903|UniProtKB=A0ACM8FNJ4 A0ACM8FNJ4 PTHR24241:SF117 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE S RECEPTOR-LIKE G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;biological regulation#GO:0065007;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8042879|UniProtKB=A0ACM8ENM6 A0ACM8ENM6 LOC8042879 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8052725|UniProtKB=A0ACM8DQ17 A0ACM8DQ17 PTHR16222:SF24 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH3 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;response to reactive oxygen species#GO:0000302;macromolecule metabolic process#GO:0043170;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;metabolic process#GO:0008152 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8041606|UniProtKB=A0ACM8DKP0 A0ACM8DKP0 pAbp PTHR24012:SF935 RNA BINDING PROTEIN LD36772P-RELATED binding#GO:0005488;poly(A) binding#GO:0008143;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;single-stranded RNA binding#GO:0003727;mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8053229|UniProtKB=A0ACM8DWH1 A0ACM8DWH1 LOC8053229 PTHR24248:SF174 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR ALPHA2-ADRENERGIC-LIKE OCTOPAMINE RECEPTOR, ISOFORM B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115325653|UniProtKB=A0ACM8E4Z7 A0ACM8E4Z7 LOC115325653 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058 reductase#PC00198 IXOSC|EnsemblGenome=LOC120838946|UniProtKB=A0ACM8FV39 A0ACM8FV39 LOC120838946 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC120836499|UniProtKB=A0ACM8EF62 A0ACM8EF62 LOC120836499 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8029224|UniProtKB=A0ACM8DHT1 A0ACM8DHT1 LOC8029224 PTHR43344:SF2 PHOSPHOSERINE PHOSPHATASE PHOSPHOSERINE PHOSPHATASE ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;magnesium ion binding#GO:0000287;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578 small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid biosynthetic process#GO:0170038;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 Serine glycine biosynthesis#P02776>Phosphoserine phosphatase#P03159 IXOSC|EnsemblGenome=LOC120846980|UniProtKB=A0ACM8F4J6 A0ACM8F4J6 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;reproductive process#GO:0022414;homologous recombination#GO:0035825;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;nucleotide-excision repair#GO:0006289;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;response to stimulus#GO:0050896;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8036201|UniProtKB=A0ACM8EBY1 A0ACM8EBY1 LOC8036201 PTHR22891:SF111 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC8037980|UniProtKB=A0ACM8EIV1 A0ACM8EIV1 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8032503|UniProtKB=A0ACM8EC53 A0ACM8EC53 LOC8032503 PTHR12191:SF37 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP8 symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;zinc ion transmembrane transporter activity#GO:0005385;bicarbonate transmembrane transporter activity#GO:0015106;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;import across plasma membrane#GO:0098739;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8026371|UniProtKB=A0ACM8DHP7 A0ACM8DHP7 rngo PTHR12917:SF1 ASPARTYL PROTEASE DDI-RELATED AT13091P endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;aspartic protease#PC00053 IXOSC|EnsemblGenome=LOC121833324|UniProtKB=A0ACM8FJ43 A0ACM8FJ43 LOC121833324 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8037775|UniProtKB=A0ACM8EC99 A0ACM8EC99 LOC8037775 PTHR22793:SF12 MYOCARDIN-RELATED TRANSCRIPTION FACTOR-RELATED MYOCARDIN-RELATED TRANSCRIPTION FACTOR, ISOFORM H DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115311371|UniProtKB=A0ACM8FN49 A0ACM8FN49 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115322654|UniProtKB=A0ACM8E2A4 A0ACM8E2A4 LOC115322654 PTHR46223:SF4 HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H HISTONE-LYSINE N-METHYLTRANSFERASE-RELATED protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC121838522|UniProtKB=A0ACM8G8K0 A0ACM8G8K0 LOC121838522 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8034310|UniProtKB=A0ACM8G1J8 A0ACM8G1J8 RpIIIC53 PTHR13408:SF0 DNA-DIRECTED RNA POLYMERASE III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC4 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170 protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120837981|UniProtKB=A0ACM8EIW1 A0ACM8EIW1 LOC120837981 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120836886|UniProtKB=A0ACM8EG00 A0ACM8EG00 LOC120836886 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051487|UniProtKB=A0ACM8ECE9 A0ACM8ECE9 LOC8051487 PTHR46520:SF1 SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL SERINE BETA-LACTAMASE-LIKE PROTEIN LACTB, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;primary metabolic process#GO:0044238;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of lipid metabolic process#GO:0019216;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120837320|UniProtKB=A0ACM8FLV0 A0ACM8FLV0 LOC121838535 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC115314998|UniProtKB=A0ACM8DUE2 A0ACM8DUE2 Rpn12 PTHR12387:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 8 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 proteasome complex#GO:0000502;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;peptidase complex#GO:1905368;proteasome regulatory particle, lid subcomplex#GO:0008541;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC8034618|UniProtKB=A0ACM8E8Z9 A0ACM8E8Z9 l(3)80Fg PTHR44303:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 DNAJ HOMOLOG SUBFAMILY C MEMBER 16 catabolic process#GO:0009056;macroautophagy#GO:0016236;biological regulation#GO:0065007;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;autophagosome organization#GO:1905037;regulation of cellular component size#GO:0032535;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;process utilizing autophagic mechanism#GO:0061919;regulation of biological quality#GO:0065008;vacuole organization#GO:0007033;regulation of anatomical structure size#GO:0090066;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8035286|UniProtKB=A0ACM8E779 A0ACM8E779 LOC8035286 PTHR15496:SF2 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 FAMILY GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 4 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;transcription factor TFIIIC complex#GO:0000127 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8028024|UniProtKB=A0ACM8EFR3 A0ACM8EFR3 LOC8028024 PTHR21557:SF2 CORDON-BLEU CORDON-BLEU PROTEIN-LIKE 1 IXOSC|EnsemblGenome=LOC115319386|UniProtKB=A0ACM8DZ79 A0ACM8DZ79 LOC115319386 PTHR32235:SF1 NON-HOMOLOGOUS END-JOINING FACTOR 1 NON-HOMOLOGOUS END-JOINING FACTOR 1 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302 nucleus#GO:0005634;DNA repair complex#GO:1990391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8036714|UniProtKB=A0ACM8FI49 A0ACM8FI49 LOC8036714 PTHR28630:SF3 FAMILY NOT NAMED PROSTAMIDE_PROSTAGLANDIN F SYNTHASE IXOSC|EnsemblGenome=LOC8037527|UniProtKB=A0ACM8DK40 A0ACM8DK40 LOC8037527 PTHR12461:SF110 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED JMJC DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8038197|UniProtKB=A0ACM8DTR2 A0ACM8DTR2 LOC8038197 PTHR11559:SF417 CARBOXYLESTERASE NEUROTACTIN esterase#PC00097 IXOSC|EnsemblGenome=LOC121837392|UniProtKB=A0ACM8G335 A0ACM8G335 LOC121837392 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848105|UniProtKB=A0ACM8F5F5 A0ACM8F5F5 LOC120848105 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033290|UniProtKB=A0ACM8FF93 A0ACM8FF93 LOC8033290 PTHR24393:SF175 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120837109|UniProtKB=A0ACM8EHK9 A0ACM8EHK9 LOC120837109 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC8025825|UniProtKB=A0ACM8DGF6 A0ACM8DGF6 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311452|UniProtKB=A0ACM8F3K1 A0ACM8F3K1 LOC115311452 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120840514|UniProtKB=A0ACM8ENV3 A0ACM8ENV3 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839869|UniProtKB=A0ACM8EN96 A0ACM8EN96 PTHR16466:SF6 TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere capping#GO:0016233;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;telomere maintenance via telomere lengthening#GO:0010833;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;telomere organization#GO:0032200;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;intracellular organelle#GO:0043229;nuclear telomere cap complex#GO:0000783;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8026480|UniProtKB=A0ACM8DUT0 A0ACM8DUT0 LOC8026480 PTHR47507:SF6 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793 IXOSC|EnsemblGenome=LOC8023450|UniProtKB=A0ACM8DH47 A0ACM8DH47 LOC8023450 PTHR24390:SF222 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8025979|UniProtKB=A0ACM8FCE1 A0ACM8FCE1 LOC8025979 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120838198|UniProtKB=A0ACM8EJE0 A0ACM8EJE0 ctrip PTHR45670:SF13 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;response to stress#GO:0006950;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;DNA damage response#GO:0006974;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115315084|UniProtKB=A0ACM8EID7 A0ACM8EID7 LOC115315084 PTHR11085:SF7 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED DEACETYLASE SIRTUIN-TYPE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC120849758|UniProtKB=A0ACM8F8F9 A0ACM8F8F9 LOC120849758 PTHR46880:SF5 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327775|UniProtKB=A0ACM8E7B2 A0ACM8E7B2 LOC115327775 PTHR19303:SF82 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120848988|UniProtKB=A0ACM8FKP0 A0ACM8FKP0 LOC120848988 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120850875|UniProtKB=A0ACM8FAY8 A0ACM8FAY8 LOC120850875 PTHR24381:SF470 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115314983|UniProtKB=A0ACM8FQ21 A0ACM8FQ21 LOC115314983 PTHR24056:SF171 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 20 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8043875|UniProtKB=A0ACM8F8T6 A0ACM8F8T6 LOC8043875 PTHR24208:SF166 LIM/HOMEOBOX PROTEIN LHX LIM HOMEOBOX TRANSCRIPTION FACTOR 1 ALPHA, ISOFORM B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8051589|UniProtKB=A0ACM8FF61 A0ACM8FF61 Eb1 PTHR10623:SF6 MICROTUBULE-ASSOCIATED PROTEIN RP/EB FAMILY MEMBER EB1, ISOFORM F-RELATED binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component assembly#GO:0022607;protein localization to microtubule cytoskeleton#GO:0072698;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;cell cycle#GO:0007049;protein localization to cytoskeleton#GO:0044380;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of microtubule-based process#GO:0032886;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226 intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;supramolecular fiber#GO:0099512;microtubule#GO:0005874;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule end#GO:1990752;cytoplasmic microtubule#GO:0005881;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8026368|UniProtKB=A0ACM8DT01 A0ACM8DT01 LOC8026368 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120845301|UniProtKB=A0ACM8FGY8 A0ACM8FGY8 LOC120845301 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310249|UniProtKB=A0ACM8DPJ7 A0ACM8DPJ7 LOC115310249 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032494|UniProtKB=A0ACM8FIV5 A0ACM8FIV5 magu PTHR12352:SF30 SECRETED MODULAR CALCIUM-BINDING PROTEIN FI05255P extracellular matrix binding#GO:0050840;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539;binding#GO:0005488;heparin binding#GO:0008201 cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8030852|UniProtKB=A0ACM8DSD5 A0ACM8DSD5 LOC8030852 PTHR19444:SF56 UNC-93 RELATED UNC93-LIKE PROTEIN transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 regulation of muscle contraction#GO:0006937;regulation of system process#GO:0044057;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;homeostatic process#GO:0042592;regulation of multicellular organismal process#GO:0051239 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;contractile muscle fiber#GO:0043292;cell periphery#GO:0071944;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737 membrane-bound signaling molecule#PC00152 IXOSC|EnsemblGenome=LOC121837998|UniProtKB=A0ACM8G657 A0ACM8G657 LOC121837998 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115328985|UniProtKB=A0ACM8E9D7 A0ACM8E9D7 LOC115328985 PTHR20922:SF13 DNL-TYPE ZINC FINGER PROTEIN DNL-TYPE ZINC FINGER PROTEIN protein localization to organelle#GO:0033365;primary metabolic process#GO:0044238;localization#GO:0051179;protein metabolic process#GO:0019538;chaperone-mediated protein complex assembly#GO:0051131;mitochondrial protein import pathway#GO:7770058;biosynthetic process#GO:0009058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;mitochondrial transport#GO:0006839;protein folding#GO:0006457;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;cellular component assembly#GO:0022607;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component biogenesis#GO:0044085;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;intracellular protein transmembrane transport#GO:0065002;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC8032268|UniProtKB=A0ACM8DSF1 A0ACM8DSF1 LOC8032268 PTHR10896:SF74 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE P transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120837860|UniProtKB=A0ACM8EIF3 A0ACM8EIF3 LOC120837860 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844647|UniProtKB=A0ACM8EZ77 A0ACM8EZ77 LOC120844647 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8032583|UniProtKB=A0ACM8EDE0 A0ACM8EDE0 LOC8032583 PTHR10780:SF18 MITOCHONDRIAL CARRIER HOMOLOG LD43650P molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein insertion into mitochondrial outer membrane#GO:0045040;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104 cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 IXOSC|EnsemblGenome=LOC121835615|UniProtKB=A0ACM8FUF9 A0ACM8FUF9 LOC121835615 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8042093|UniProtKB=A0ACM8E6F9 A0ACM8E6F9 LOC8042093 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC115318852|UniProtKB=A0ACM8EZU1 A0ACM8EZU1 LOC115318852 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042554|UniProtKB=A0ACM8EA96 A0ACM8EA96 LOC8042554 PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8051494|UniProtKB=A0ACM8EDZ8 A0ACM8EDZ8 LOC8051494 PTHR12011:SF347 ADHESION G-PROTEIN COUPLED RECEPTOR LATROPHILIN CIRL plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120842438|UniProtKB=A0ACM8ETU7 A0ACM8ETU7 LOC120842438 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8036084|UniProtKB=A0ACM8EKV0 A0ACM8EKV0 cnk PTHR12844:SF42 CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS CONNECTOR ENHANCER OF KSR PROTEIN CNK MAP kinase scaffold activity#GO:0005078;signaling adaptor activity#GO:0035591;structural molecule activity#GO:0005198;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein complex scaffold activity#GO:0140378 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886;membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053652|UniProtKB=A0ACM8EBQ8 A0ACM8EBQ8 LOC8053652 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC120850688|UniProtKB=A0ACM8FAV0 A0ACM8FAV0 LOC120850688 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8043425|UniProtKB=A0ACM8E1T9 A0ACM8E1T9 LOC8043425 PTHR10683:SF44 TRANSALDOLASE TRANSALDOLASE transaldolase activity#GO:0004801;transketolase or transaldolase activity#GO:0016744;transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;pentose-phosphate shunt#GO:0006098;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;nucleotide metabolic process#GO:0009117;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;aldolase#PC00044;lyase#PC00144 Pentose phosphate pathway#P02762>Transaldolase#P03081 IXOSC|EnsemblGenome=LOC121046937|UniProtKB=A0ACM8G3Q6 A0ACM8G3Q6 LOC121046937 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8024498|UniProtKB=A0ACM8E9V4 A0ACM8E9V4 LOC8024498 PTHR22306:SF2 CHROMOSOME 7 OPEN READING FRAME 50 PROTEIN CHOLESIN IXOSC|EnsemblGenome=LOC8032247|UniProtKB=A0ACM8F5V0 A0ACM8F5V0 MED17 PTHR13114:SF7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 17 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8032160|UniProtKB=A0ACM8DRA4 A0ACM8DRA4 LOC8032160 PTHR10366:SF853 NAD DEPENDENT EPIMERASE/DEHYDRATASE GH25466P catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolite interconversion enzyme#PC00262;dehydratase#PC00091;lyase#PC00144 IXOSC|EnsemblGenome=LOC115328799|UniProtKB=A0ACM8EWT9 A0ACM8EWT9 LOC115328799 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121832924|UniProtKB=A0ACM8FT75 A0ACM8FT75 LOC121832924 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;serine-type peptidase activity#GO:0008236 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8053121|UniProtKB=A0ACM8DQJ1 A0ACM8DQJ1 LOC8053121 PTHR24258:SF142 SERINE PROTEASE-RELATED PHENOLOXIDASE-ACTIVATING FACTOR 2 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120845329|UniProtKB=A0ACM8F1I4 A0ACM8F1I4 LOC120845329 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8051443|UniProtKB=A0ACM8DNE3 A0ACM8DNE3 IFT54 PTHR31363:SF0 TRAF3-INTERACTING PROTEIN 1 TRAF3-INTERACTING PROTEIN 1 cilium organization#GO:0044782;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;regulation of microtubule cytoskeleton organization#GO:0070507;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;localization#GO:0051179;regulation of microtubule-based process#GO:0032886;organelle assembly#GO:0070925;intraciliary transport#GO:0042073;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;regulation of cytoskeleton organization#GO:0051493;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;axoneme#GO:0005930;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intraciliary transport particle B#GO:0030992;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;microtubule cytoskeleton#GO:0015630 IXOSC|EnsemblGenome=LOC115331076|UniProtKB=A0ACM8F1A9 A0ACM8F1A9 LOC115331076 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8030854|UniProtKB=A0ACM8DVU8 A0ACM8DVU8 LOC8030854 PTHR43861:SF1 TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120846433|UniProtKB=A0ACM8F390 A0ACM8F390 LOC120846433 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026389|UniProtKB=A0ACM8E573 A0ACM8E573 LOC8026389 PTHR23430:SF69 HISTONE H2A MACRO DOMAIN-CONTAINING PROTEIN structural molecule activity#GO:0005198 negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase I#GO:0006356;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;protein-DNA complex#GO:0032993;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8030671|UniProtKB=A0ACM8FG48 A0ACM8FG48 LOC8030671 PTHR46753:SF2 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;regulation of protein-containing complex disassembly#GO:0043244;positive regulation of autophagy#GO:0010508;positive regulation of biological process#GO:0048518;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;regulation of macroautophagy#GO:0016241;microtubule-based process#GO:0007017;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;positive regulation of macroautophagy#GO:0016239;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;positive regulation of metabolic process#GO:0009893;cellular localization#GO:0051641;positive regulation of organelle organization#GO:0010638;positive regulation of cellular component organization#GO:0051130;microtubule-based transport#GO:0099111;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;vesicle localization#GO:0051648;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;positive regulation of catabolic process#GO:0009896;vesicle cytoskeletal trafficking#GO:0099518;regulation of catabolic process#GO:0009894;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;regulation of autophagosome maturation#GO:1901096;transport#GO:0006810;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;localization#GO:0051179;organelle localization#GO:0051640 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;autophagosome#GO:0005776;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;lytic vacuole#GO:0000323;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;vacuole#GO:0005773 IXOSC|EnsemblGenome=LOC8051028|UniProtKB=A0ACM8DLE5 A0ACM8DLE5 Taf8 PTHR46469:SF1 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 General transcription by RNA polymerase I#P00022>TAF-IB#P00650;General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>TAF-IC#P00649;General transcription regulation#P00023>TBP-associated factors#P00658;General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 IXOSC|EnsemblGenome=LOC8036285|UniProtKB=A0ACM8EJD8 A0ACM8EJD8 LOC8036285 PTHR45632:SF36 LD33804P RING ZINC FINGER-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8044013|UniProtKB=A0ACM8ED98 A0ACM8ED98 flfl PTHR23318:SF27 ATP SYNTHASE GAMMA-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 3 enzyme activator activity#GO:0008047;phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cellular response to stimulus#GO:0051716;regulation of double-strand break repair#GO:2000779;regulation of cellular response to stress#GO:0080135;cellular response to stress#GO:0033554;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;DNA damage response#GO:0006974;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein serine/threonine phosphatase complex#GO:0008287;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC8040135|UniProtKB=A0ACM8DKI2 A0ACM8DKI2 LOC8040135 PTHR15682:SF2 UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG UNHEALTHY RIBOSOME BIOGENESIS PROTEIN 2 HOMOLOG ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115309011|UniProtKB=A0ACM8EW92 A0ACM8EW92 LOC115309011 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120838403|UniProtKB=A0ACM8EJ72 A0ACM8EJ72 LOC120838403 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8032405|UniProtKB=A0ACM8DJG9 A0ACM8DJG9 LOC8032405 PTHR42886:SF96 RE40534P-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 hydrolase activity#GO:0016787;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;carboxylic ester hydrolase activity#GO:0052689;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycerophospholipase activity#GO:0004620;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;homeostatic process#GO:0042592;phospholipid metabolic process#GO:0006644;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;chemical homeostasis#GO:0048878;glycerophospholipid biosynthetic process#GO:0046474 lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115330098|UniProtKB=A0ACM8EAT3 A0ACM8EAT3 LOC115330098 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115331157|UniProtKB=A0ACM8EC89 A0ACM8EC89 LOC115331157 PTHR24347:SF459 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE H1 HOMOLOG-RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8031776|UniProtKB=A0ACM8EZ44 A0ACM8EZ44 LOC8031776 PTHR45911:SF10 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of trans-synaptic signaling#GO:0099177;regulation of neurotransmitter secretion#GO:0046928;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of secretion by cell#GO:1903530;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of secretion#GO:0051046;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588 transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;presynapse#GO:0098793;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382 IXOSC|EnsemblGenome=LOC115317080|UniProtKB=A0ACM8F7F2 A0ACM8F7F2 LOC115317080 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120839772|UniProtKB=A0ACM8EN49 A0ACM8EN49 LOC120839772 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034971|UniProtKB=A0ACM8EEP7 A0ACM8EEP7 LOC8034971 PTHR47772:SF23 ZINC FINGER PROTEIN 200 ZINC FINGER PROTEIN 628 IXOSC|EnsemblGenome=LOC115321504|UniProtKB=A0ACM8E161 A0ACM8E161 LOC115321504 PTHR11426:SF263 HISTONE H3 HISTONE H3.X-RELATED cellular component assembly#GO:0022607;chromosome localization#GO:0050000;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;organelle fission#GO:0048285;kinetochore organization#GO:0051383;localization#GO:0051179;organelle localization#GO:0051640;nuclear division#GO:0000280;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120845242|UniProtKB=A0ACM8FLQ7 A0ACM8FLQ7 LOC120845242 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033944|UniProtKB=A0ACM8E3T0 A0ACM8E3T0 LOC8033944 PTHR12295:SF35 FURRY-RELATED PROTEIN FURRY cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;establishment or maintenance of cell polarity#GO:0007163;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cell division site#GO:0032153;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115327403|UniProtKB=A0ACM8EVS4 A0ACM8EVS4 LOC115327403 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115329154|UniProtKB=A0ACM8FXB4 A0ACM8FXB4 LOC115329154 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309845|UniProtKB=A0ACM8DP69 A0ACM8DP69 TTLL15 PTHR47113:SF1 LD09343P LD09343P IXOSC|EnsemblGenome=LOC121837220|UniProtKB=A0ACM8G2W1 A0ACM8G2W1 LOC121837220 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120849034|UniProtKB=A0ACM8F604 A0ACM8F604 LOC120849034 PTHR24348:SF79 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED AUTOPHAGY-RELATED 1, ISOFORM B phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 metabolic process#GO:0008152;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell growth#GO:0016049;cell projection morphogenesis#GO:0048858;autophagosome assembly#GO:0000045;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component assembly#GO:0022607;axon extension#GO:0048675;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;process utilizing autophagic mechanism#GO:0061919;developmental growth involved in morphogenesis#GO:0060560;axonogenesis#GO:0007409;neuron projection extension#GO:1990138;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;autophagy of mitochondrion#GO:0000422;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;mitophagy#GO:0000423;cellular developmental process#GO:0048869;developmental growth#GO:0048589;regulation of catabolic process#GO:0009894;neurogenesis#GO:0022008;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;reticulophagy#GO:0061709;axon development#GO:0061564;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;macroautophagy#GO:0016236;organelle assembly#GO:0070925;anatomical structure development#GO:0048856;system development#GO:0048731;vacuole organization#GO:0007033;response to starvation#GO:0042594;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;developmental cell growth#GO:0048588;piecemeal microautophagy of the nucleus#GO:0034727 phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;autophagosome#GO:0005776;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8043404|UniProtKB=A0ACM8DL50 A0ACM8DL50 LOC8043404 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8040410|UniProtKB=A0ACM8EUJ0 A0ACM8EUJ0 TBPH PTHR48033:SF9 RNA-BINDING (RRM/RBD/RNP MOTIFS) FAMILY PROTEIN TAR DNA-BINDING PROTEIN 43 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120836772|UniProtKB=A0ACM8EGQ7 A0ACM8EGQ7 LOC120836772 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121838110|UniProtKB=A0ACM8G6G1 A0ACM8G6G1 LOC121838110 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8032722|UniProtKB=A0ACM8DZN9 A0ACM8DZN9 LOC8032722 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 catabolic process#GO:0009056;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843113|UniProtKB=A0ACM8EV61 A0ACM8EV61 LOC120843113 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120850663|UniProtKB=A0ACM8FAS1 A0ACM8FAS1 LOC120850663 PTHR12949:SF0 RNA POLYMERASE III DNA DIRECTED -RELATED DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC115331806|UniProtKB=A0ACM8EV02 A0ACM8EV02 LOC115331806 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838355|UniProtKB=A0ACM8EJ19 A0ACM8EJ19 LOC120838355 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC120841725|UniProtKB=A0ACM8ETC2 A0ACM8ETC2 LOC120841725 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8035479|UniProtKB=A0ACM8E0E3 A0ACM8E0E3 LOC8035479 PTHR23404:SF2 MOLYBDOPTERIN SYNTHASE RELATED MOLYBDOPTERIN SYNTHASE CATALYTIC SUBUNIT cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8023211|UniProtKB=A0ACM8DGH6 A0ACM8DGH6 LOC8023211 PTHR11407:SF63 LYSOZYME C LYSOZYME hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783;lysozyme activity#GO:0003796;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC120841722|UniProtKB=A0ACM8ESA1 A0ACM8ESA1 LOC120841722 PTHR45620:SF44 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTOR, ORPHAN-RELATED molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8041239|UniProtKB=A0ACM8EW30 A0ACM8EW30 LOC8041239 PTHR13407:SF0 RNF121 PROTEIN FI05221P catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8032706|UniProtKB=A0ACM8FI77 A0ACM8FI77 LOC8032706 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8038928|UniProtKB=A0ACM8E406 A0ACM8E406 LOC8038928 PTHR22726:SF1 METALLOENDOPEPTIDASE OMA1 METALLOENDOPEPTIDASE OMA1, MITOCHONDRIAL metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;primary metabolic process#GO:0044238;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121835763|UniProtKB=A0ACM8FV14 A0ACM8FV14 LOC121835763 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023173|UniProtKB=A0ACM8E232 A0ACM8E232 inc PTHR14958:SF29 POTASSIUM CHANNEL TETRAMERISATION DOMAIN CONTAINING PROTEIN INSOMNIAC, ISOFORM B binding#GO:0005488;protein binding#GO:0005515 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8036685|UniProtKB=A0ACM8EBX4 A0ACM8EBX4 LOC8036685 PTHR45797:SF1 RAD54-LIKE HELICASE ARIP4 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;catalytic activity, acting on a nucleic acid#GO:0140640;transcription regulator activity#GO:0140110;ATP-dependent activity#GO:0140657 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8032676|UniProtKB=A0ACM8DTT2 A0ACM8DTT2 LOC8032676 PTHR12317:SF0 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYLTRANSFERASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8041000|UniProtKB=A0ACM8DTW0 A0ACM8DTW0 14-3-3zeta PTHR18860:SF184 14-3-3 PROTEIN 14-3-3 PROTEIN ZETA scaffold/adaptor protein#PC00226 PI3 kinase pathway#P00048>14-3-3#P01206;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624;Parkinson disease#P00049>14-3-3#P01238 IXOSC|EnsemblGenome=LOC8032003|UniProtKB=A0ACM8G3T9 A0ACM8G3T9 Aplip1 PTHR47437:SF4 JNK-INTERACTING PROTEIN 1-LIKE PROTEIN C-JUN-AMINO-TERMINAL KINASE-INTERACTING PROTEIN 1-LIKE signaling adaptor activity#GO:0035591;protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;MAP kinase scaffold activity#GO:0005078;structural molecule activity#GO:0005198;molecular adaptor activity#GO:0060090;protein complex scaffold activity#GO:0140378 intracellular signal transduction#GO:0035556;MAPK cascade#GO:0000165;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;JNK cascade#GO:0007254 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8035110|UniProtKB=A0ACM8E1R6 A0ACM8E1R6 LOC8035110 PTHR11961:SF56 CYTOCHROME C CYTOCHROME C electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;aerobic respiration#GO:0009060;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;mitochondrial intermembrane space#GO:0005758;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP synthesis#P02721>Cyt C#P02798;Apoptosis signaling pathway#P00006>Cytochrome C#P00322 IXOSC|EnsemblGenome=LOC115315011|UniProtKB=A0ACM8FSG4 A0ACM8FSG4 LOC115315011 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;glutathione metabolic process#GO:0006749;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 isomerase#PC00135 IXOSC|EnsemblGenome=LOC121837000|UniProtKB=A0ACM8G160 A0ACM8G160 LOC121837000 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system development#GO:0048731;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;heart development#GO:0007507;circulatory system development#GO:0072359 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8030793|UniProtKB=A0ACM8DYT7 A0ACM8DYT7 APC10 PTHR12936:SF0 ANAPHASE-PROMOTING COMPLEX 10 ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cell cycle#GO:0007049;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538 protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Cell cycle#P00013>APC#P00481 IXOSC|EnsemblGenome=LOC8037044|UniProtKB=A0ACM8DHV2 A0ACM8DHV2 LOC8037044 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8031599|UniProtKB=A0ACM8E4I6 A0ACM8E4I6 LOC8031599 PTHR45620:SF15 PDF RECEPTOR-LIKE PROTEIN-RELATED DIURETIC HORMONE RECEPTOR hormone binding#GO:0042562;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;binding#GO:0005488;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8038317|UniProtKB=A0ACM8FBQ6 A0ACM8FBQ6 LOC8038317 PTHR23220:SF133 INTEGRIN ALPHA INTEGRIN ALPHA-PS2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell surface receptor signaling pathway#GO:0007166 membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;protein complex involved in cell adhesion#GO:0098636;cell periphery#GO:0071944;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;integrin complex#GO:0008305 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 IXOSC|EnsemblGenome=LOC115316745|UniProtKB=A0ACM8DWX5 A0ACM8DWX5 LOC115316745 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120837423|UniProtKB=A0ACM8EI12 A0ACM8EI12 LOC120837423 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115331827|UniProtKB=A0ACM8EDJ0 A0ACM8EDJ0 LOC115331827 PTHR11783:SF358 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4A1 transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8043554|UniProtKB=A0ACM8E2N3 A0ACM8E2N3 PTHR32463:SF0 L-FUCOSE KINASE L-FUCOSE KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-sugar metabolic process#GO:0009225;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137 transferase#PC00220;kinase#PC00137 IXOSC|EnsemblGenome=LOC115318955|UniProtKB=A0ACM8F4Z8 A0ACM8F4Z8 LOC115318955 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025808|UniProtKB=A0ACM8FIW7 A0ACM8FIW7 dbe PTHR12581:SF0 HIV-1 REV BINDING PROTEIN 2, 3 KRR1 SMALL SUBUNIT PROCESSOME COMPONENT HOMOLOG intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120838608|UniProtKB=A0ACM8EL72 A0ACM8EL72 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC115313619|UniProtKB=A0ACM8EPP3 A0ACM8EPP3 LOC115313619 PTHR46609:SF6 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN EXONUCLEASE, PHAGE-TYPE_RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115320021|UniProtKB=A0ACM8FM64 A0ACM8FM64 LOC115320021 PTHR23235:SF194 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8039166|UniProtKB=A0ACM8EBV2 A0ACM8EBV2 for PTHR24353:SF111 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;receptor guanylyl cyclase signaling pathway#GO:0007168;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Endothelin signaling pathway#P00019>PKG#P00567 IXOSC|EnsemblGenome=LOC120844371|UniProtKB=A0ACM8EYG7 A0ACM8EYG7 mRpL12 PTHR45987:SF29 39S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN BL12M binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729;RNA binding#GO:0003723;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8037732|UniProtKB=A0ACM8DMG1 A0ACM8DMG1 Evi5 PTHR47219:SF22 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE RAB-GAP TBC DOMAIN-CONTAINING PROTEIN GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;enzyme binding#GO:0019899 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC8039140|UniProtKB=A0ACM8FQU1 A0ACM8FQU1 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037358|UniProtKB=A0ACM8E8B7 A0ACM8E8B7 LOC8037358 PTHR13101:SF1 PHOSPHOMEVALONATE KINASE PHOSPHOMEVALONATE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, phosphate group as acceptor#GO:0016776 phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;isoprenoid biosynthetic process#GO:0008299;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phospholipid biosynthetic process#GO:0008654;nucleoside phosphate metabolic process#GO:0006753;phospholipid metabolic process#GO:0006644;acetyl-CoA metabolic process#GO:0006084;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;acyl-CoA metabolic process#GO:0006637 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 Cholesterol biosynthesis#P00014>Phosphomevalonate kinase#P00500 IXOSC|EnsemblGenome=LOC115328494|UniProtKB=A0ACM8F1Q7 A0ACM8F1Q7 LOC115328494 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 IXOSC|EnsemblGenome=LOC115321381|UniProtKB=A0ACM8E1W0 A0ACM8E1W0 LOC115321381 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833514|UniProtKB=A0ACM8FL41 A0ACM8FL41 LOC121833514 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC120846860|UniProtKB=A0ACM8F3F7 A0ACM8F3F7 LOC120846860 PTHR11604:SF0 PROFILIN PROFILIN binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin monomer binding#GO:0003785;protein binding#GO:0005515 cell cortex#GO:0005938;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 Cytoskeletal regulation by Rho GTPase#P00016>Profilin#P00521 IXOSC|EnsemblGenome=LOC8053241|UniProtKB=A0ACM8DGX6 A0ACM8DGX6 LOC8053241 PTHR24072:SF398 RHO FAMILY GTPASE RAS-LIKE GTP-BINDING PROTEIN RHO1 kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cell migration#GO:0016477;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;signaling#GO:0023052;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043 cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 small GTPase#PC00208;G-protein#PC00020 Ras Pathway#P04393>Rho#P04578;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507 IXOSC|EnsemblGenome=LOC8031743|UniProtKB=A0ACM8G230 A0ACM8G230 LOC8031743 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120844163|UniProtKB=A0ACM8EY05 A0ACM8EY05 LOC120844163 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043061|UniProtKB=A0ACM8E7X9 A0ACM8E7X9 LOC8043061 PTHR23092:SF15 POLY(A) RNA POLYMERASE INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;modification-dependent macromolecule catabolic process#GO:0043632;RNA biosynthetic process#GO:0032774;catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC121837600|UniProtKB=A0ACM8G554 A0ACM8G554 LOC121837600 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120840637|UniProtKB=A0ACM8G6A2 A0ACM8G6A2 LOC120840637 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835912|UniProtKB=A0ACM8FX38 A0ACM8FX38 LOC121835912 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8024265|UniProtKB=A0ACM8EH94 A0ACM8EH94 LOC8024265 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;biosynthetic process#GO:0009058;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115314096|UniProtKB=A0ACM8G6L7 A0ACM8G6L7 LOC115314096 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115328449|UniProtKB=A0ACM8F2A7 A0ACM8F2A7 LOC115328449 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037228|UniProtKB=A0ACM8EPX6 A0ACM8EPX6 LOC8037228 PTHR22255:SF10 LP06548P ARGUS, ISOFORM A vesicle fusion#GO:0006906;catabolic process#GO:0009056;cellular component organization#GO:0016043;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;membrane organization#GO:0061024;macroautophagy#GO:0016236;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;autophagy#GO:0006914;cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152 IXOSC|EnsemblGenome=LOC115326322|UniProtKB=A0ACM8EIE2 A0ACM8EIE2 LOC115326322 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115325463|UniProtKB=A0ACM8DYN7 A0ACM8DYN7 LOC115325463 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120842316|UniProtKB=A0ACM8ETI1 A0ACM8ETI1 LOC120842316 PTHR45620:SF40 PDF RECEPTOR-LIKE PROTEIN-RELATED G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120839141|UniProtKB=A0ACM8FKJ8 A0ACM8FKJ8 LOC120839141 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8029936|UniProtKB=A0ACM8E0P4 A0ACM8E0P4 LOC8029936 PTHR21405:SF0 CDNA SEQUENCE BC021608 TETRATRICOPEPTIDE REPEAT PROTEIN 36 IXOSC|EnsemblGenome=LOC8026768|UniProtKB=A0ACM8ETF7 A0ACM8ETF7 LOC8026768 PTHR10099:SF1 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE PHOSPHORIBOSYLFORMYLGLYCINAMIDINE SYNTHASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 De novo purine biosynthesis#P02738>Phosphoribosylformylglycinamide synthase#P02898 IXOSC|EnsemblGenome=LOC8039778|UniProtKB=A0ACM8F104 A0ACM8F104 LOC8039778 PTHR13382:SF90 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B F-BOX_LRR-REPEAT PROTEIN 15-LIKE LEUCIN RICH REPEAT DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC115333140|UniProtKB=A0ACM8EEL6 A0ACM8EEL6 LOC115333140 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115327801|UniProtKB=A0ACM8G1E3 A0ACM8G1E3 LOC115327801 PTHR23426:SF65 FERREDOXIN/ADRENODOXIN ADRENODOXIN-LIKE PROTEIN 2, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;electron transport chain#GO:0022900 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 IXOSC|EnsemblGenome=LOC8039590|UniProtKB=A0ACM8DKD9 A0ACM8DKD9 LOC8039590 PTHR43602:SF1 FAMILY NOT NAMED ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8043547|UniProtKB=A0ACM8E5C0 A0ACM8E5C0 LOC8043547 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8024154|UniProtKB=A0ACM8DT04 A0ACM8DT04 Pi4KIIalpha PTHR12865:SF1 PHOSPHATIDYLINOSITOL 4-KINASE TYPE-II PHOSPHATIDYLINOSITOL 4-KINASE TYPE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;catalytic activity#GO:0003824;transferase activity#GO:0016740 lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;endosome organization#GO:0007032;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;endomembrane system organization#GO:0010256;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;Golgi organization#GO:0007030;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus#GO:0005794 transferase#PC00220;metabolite interconversion enzyme#PC00262;kinase#PC00137 IXOSC|EnsemblGenome=LOC120849604|UniProtKB=A0ACM8F867 A0ACM8F867 und PTHR45777:SF2 METHIONINE AMINOPEPTIDASE 2 METHIONINE AMINOPEPTIDASE 2 metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8029912|UniProtKB=A0ACM8FVN1 A0ACM8FVN1 LOC8029912 PTHR14791:SF56 BOMB/KIRA PROTEINS PROTEIN KIBRA protein binding#GO:0005515;kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;regulation of multicellular organismal process#GO:0051239;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell migration#GO:0016477;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;regulation of developmental process#GO:0050793;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;regulation of macromolecule metabolic process#GO:0060255;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;negative regulation of multicellular organismal process#GO:0051241;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8037455|UniProtKB=A0ACM8EWX3 A0ACM8EWX3 LOC8037455 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8036945|UniProtKB=A0ACM8E320 A0ACM8E320 LOC8036945 PTHR23089:SF18 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT2 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 nucleotide phosphatase#PC00173 IXOSC|EnsemblGenome=LOC115316537|UniProtKB=A0ACM8G3E9 A0ACM8G3E9 LOC115316537 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115327763|UniProtKB=A0ACM8FK33 A0ACM8FK33 LOC121833509 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC121045711|UniProtKB=A0ACM8G6V5 A0ACM8G6V5 LOC121045711 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8036170|UniProtKB=A0ACM8EXP2 A0ACM8EXP2 LOC8036170 PTHR43757:SF11 AMINOMETHYLTRANSFERASE SARCOSINE DEHYDROGENASE, MITOCHONDRIAL transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8024452|UniProtKB=A0ACM8EBR7 A0ACM8EBR7 LOC8024452 PTHR12231:SF278 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN KAPPA, ISOFORM A protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;synapse organization#GO:0050808;cell adhesion#GO:0007155;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253;cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121835092|UniProtKB=A0ACM8FSE0 A0ACM8FSE0 LOC121835092 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253 IXOSC|EnsemblGenome=LOC120847624|UniProtKB=A0ACM8G412 A0ACM8G412 LOC120847624 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035467|UniProtKB=A0ACM8DWH9 A0ACM8DWH9 LOC8035467 PTHR21324:SF21 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED EG:22E5.9 PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115308184|UniProtKB=A0ACM8F9C2 A0ACM8F9C2 LOC115308184 PTHR47533:SF4 PROTEIN CBG21859 AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036548|UniProtKB=A0ACM8E6W2 A0ACM8E6W2 LOC8036548 PTHR13151:SF2 CBF1 INTERACTING COREPRESSOR CIR COREPRESSOR OF RBPJ AND SPLICING REGULATOR transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 Notch signaling pathway#P00045>CoR#P01112 IXOSC|EnsemblGenome=LOC115311792|UniProtKB=A0ACM8EHS1 A0ACM8EHS1 LOC115311792 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8034523|UniProtKB=A0ACM8DJC7 A0ACM8DJC7 Cog6 PTHR21506:SF0 COMPONENT OF OLIGOMERIC GOLGI COMPLEX 6 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 6 transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;retrograde transport, vesicle recycling within Golgi#GO:0000301;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 COG complex#GO:0017119;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115323999|UniProtKB=A0ACM8EPT5 A0ACM8EPT5 LOC115323999 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115332187|UniProtKB=A0ACM8EDE3 A0ACM8EDE3 LOC115332187 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8032069|UniProtKB=A0ACM8FMC6 A0ACM8FMC6 LOC8032069 PTHR10404:SF84 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG catalytic activity#GO:0003824;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115315607|UniProtKB=A0ACM8DV26 A0ACM8DV26 LOC115315607 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;glutathione transferase activity#GO:0004364 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8053958|UniProtKB=A0ACM8DLU5 A0ACM8DLU5 LOC8053958 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC121834221|UniProtKB=A0ACM8FP91 A0ACM8FP91 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120847574|UniProtKB=A0ACM8F3H1 A0ACM8F3H1 LOC120847574 PTHR36943:SF2 CCHC-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331341|UniProtKB=A0ACM8FSK7 A0ACM8FSK7 LOC115331341 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024793|UniProtKB=A0ACM8EFL3 A0ACM8EFL3 LOC8024793 PTHR15885:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 COILED-COIL DOMAIN-CONTAINING PROTEIN 174 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115324189|UniProtKB=A0ACM8EKA0 A0ACM8EKA0 LOC115324189 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120849073|UniProtKB=A0ACM8G8Y1 A0ACM8G8Y1 LOC120849073 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120842509|UniProtKB=A0ACM8ETZ9 A0ACM8ETZ9 LOC120842509 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8041517|UniProtKB=A0ACM8DUE1 A0ACM8DUE1 LOC8041517 PTHR45683:SF18 MITOCHONDRIAL NICOTINAMIDE ADENINE DINUCLEOTIDE TRANSPORTER 1-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 32 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 IXOSC|EnsemblGenome=LOC120843855|UniProtKB=A0ACM8EX31 A0ACM8EX31 LOC120843855 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8039194|UniProtKB=A0ACM8DML4 A0ACM8DML4 LOC8039194 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8034395|UniProtKB=A0ACM8E299 A0ACM8E299 ND-ASHI PTHR12840:SF1 NADH-UBIQUINONE OXIDOREDUCTASE ASHI SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 8, MITOCHONDRIAL transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120844459|UniProtKB=A0ACM8EZT8 A0ACM8EZT8 LOC120844459 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121045960|UniProtKB=A0ACM8G8Z6 A0ACM8G8Z6 LOC121045960 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8035573|UniProtKB=A0ACM8DR77 A0ACM8DR77 LOC8035573 PTHR23345:SF15 VITELLOGENIN-RELATED VITELLOGENIN-6 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 storage protein#PC00210 IXOSC|EnsemblGenome=LOC121836874|UniProtKB=A0ACM8G0L4 A0ACM8G0L4 LOC121836874 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8038575|UniProtKB=A0ACM8FRM5 A0ACM8FRM5 LOC8038575 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC8050667|UniProtKB=A0ACM8ECK4 A0ACM8ECK4 Kpc2 PTHR46738:SF1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 UBIQUITIN-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 IXOSC|EnsemblGenome=LOC121835557|UniProtKB=A0ACM8FUU6 A0ACM8FUU6 LOC121835557 PTHR13605:SF4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 ENDOPLASMIC RETICULUM MEMBRANE PROTEIN COMPLEX SUBUNIT 7 EMC complex#GO:0072546;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120850102|UniProtKB=A0ACM8F963 A0ACM8F963 LOC120850102 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8040576|UniProtKB=A0ACM8DSW8 A0ACM8DSW8 Ire1 PTHR13954:SF6 IRE1-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transmembrane signal receptor#PC00197;tyrosine protein kinase receptor#PC00233 Alzheimer disease-presenilin pathway#P00004>Ire-1#P00144;Alzheimer disease-presenilin pathway#P00004>Ire-1 C-terminal fragment#P00125;Alzheimer disease-presenilin pathway#P00004>Ire-1 N-terminal fragment#P00110 IXOSC|EnsemblGenome=LOC8042325|UniProtKB=A0ACM8EWU2 A0ACM8EWU2 LOC8042325 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8035005|UniProtKB=A0ACM8FTE6 A0ACM8FTE6 LOC8035005 PTHR13871:SF7 THIOREDOXIN THIOREDOXIN DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120846926|UniProtKB=A0ACM8FPR7 A0ACM8FPR7 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115326023|UniProtKB=A0ACM8FAA0 A0ACM8FAA0 LOC115326023 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028016|UniProtKB=A0ACM8DJI1 A0ACM8DJI1 LOC8028016 PTHR31638:SF3 DAZ-ASSOCIATED PROTEIN 2 DAZ-ASSOCIATED PROTEIN 2 IXOSC|EnsemblGenome=LOC115332449|UniProtKB=A0ACM8FXH0 A0ACM8FXH0 LOC115332449 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841348|UniProtKB=A0ACM8ERC5 A0ACM8ERC5 LOC120841348 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835090|UniProtKB=A0ACM8FSD5 A0ACM8FSD5 LOC121835090 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115308492|UniProtKB=A0ACM8FQU8 A0ACM8FQU8 PTHR33776:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023344|UniProtKB=A0ACM8EFF8 A0ACM8EFF8 eIF3c PTHR13937:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3, SUBUNIT 8 EIF3S8 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C-RELATED translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 eukaryotic translation initiation factor 3 complex#GO:0005852;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC121833779|UniProtKB=A0ACM8FN22 A0ACM8FN22 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120836200|UniProtKB=A0ACM8G6R7 A0ACM8G6R7 LOC120836200 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115325970|UniProtKB=A0ACM8F6P7 A0ACM8F6P7 LOC115325970 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115321060|UniProtKB=A0ACM8EU15 A0ACM8EU15 LOC115321060 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=ISCI007295|UniProtKB=B7PRF6 B7PRF6 IscW_ISCW007295 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 purine-containing compound metabolic process#GO:0072521;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8040903|UniProtKB=A0ACM8EAY8 A0ACM8EAY8 LOC8040903 PTHR13255:SF1 ATAXIN-10 ATAXIN-10 neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection assembly#GO:0120031;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell projection assembly#GO:0030031;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;organelle assembly#GO:0070925;neuron development#GO:0048666;cilium organization#GO:0044782;system development#GO:0048731;anatomical structure development#GO:0048856;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030 intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;cytosol#GO:0005829;neuron projection#GO:0043005 IXOSC|EnsemblGenome=LOC8029073|UniProtKB=A0ACM8EDZ0 A0ACM8EDZ0 rau PTHR21298:SF2 GH01721P GH01721P positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 IXOSC|EnsemblGenome=LOC8031327|UniProtKB=A0ACM8DUA6 A0ACM8DUA6 LOC8031327 PTHR12341:SF7 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 1 catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;RNA binding#GO:0003723;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 exoribonuclease#PC00099;RNA metabolism protein#PC00031 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 IXOSC|EnsemblGenome=LOC115314132|UniProtKB=A0ACM8DTV0 A0ACM8DTV0 LOC115314132 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230 synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC8036437|UniProtKB=A0ACM8DJZ0 A0ACM8DJZ0 LOC8036437 PTHR15749:SF4 FANCONI-ASSOCIATED NUCLEASE 1 FANCONI-ASSOCIATED NUCLEASE 1 IXOSC|EnsemblGenome=LOC8051674|UniProtKB=A0ACM8E0F4 A0ACM8E0F4 LOC8051674 PTHR11311:SF16 SPONDIN SPONDIN-1 cellular process#GO:0009987;cell adhesion#GO:0007155 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120837313|UniProtKB=A0ACM8EGL7 A0ACM8EGL7 LOC120837313 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120843581|UniProtKB=A0ACM8EWI5 A0ACM8EWI5 LOC120843581 PTHR33147:SF39 DEFENSIN-LIKE PROTEIN 1 DEFENSIN-LIKE PROTEIN 98 response to stimulus#GO:0050896;defense response#GO:0006952;response to stress#GO:0006950 antimicrobial response protein#PC00051 IXOSC|EnsemblGenome=LOC121835356|UniProtKB=A0ACM8FU73 A0ACM8FU73 LOC121835356 PTHR43977:SF2 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN IXOSC|EnsemblGenome=LOC8041891|UniProtKB=A0ACM8FHR2 A0ACM8FHR2 LOC8041891 PTHR11964:SF1 S-ADENOSYLMETHIONINE SYNTHETASE S-ADENOSYLMETHIONINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987;biosynthetic process#GO:0009058 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;nucleotidyltransferase#PC00174 S-adenosylmethionine biosynthesis#P02773>S-Adenosyl methionine synthetase#P03143 IXOSC|EnsemblGenome=LOC121837790|UniProtKB=A0ACM8G6F9 A0ACM8G6F9 LOC121837790 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115317120|UniProtKB=A0ACM8DX65 A0ACM8DX65 LOC115317120 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115320025|UniProtKB=A0ACM8DZX6 A0ACM8DZX6 PTHR13582:SF0 M-PHASE PHOSPHOPROTEIN 6 M-PHASE PHOSPHOPROTEIN 6 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120848716|UniProtKB=A0ACM8F6L1 A0ACM8F6L1 LOC120848716 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053205|UniProtKB=A0ACM8FBG4 A0ACM8FBG4 LOC8053205 PTHR46786:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 3 ZINC FINGER MATRIN-TYPE PROTEIN 3 RNA processing factor#PC00147;RNA metabolism protein#PC00031 p53 pathway#P00059>PAG608#G04690 IXOSC|EnsemblGenome=LOC115308608|UniProtKB=A0ACM8F095 A0ACM8F095 LOC115308608 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316110|UniProtKB=A0ACM8F8N5 A0ACM8F8N5 LOC115316110 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121837778|UniProtKB=A0ACM8G6E3 A0ACM8G6E3 LOC121837778 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8030750|UniProtKB=A0ACM8E6V3 A0ACM8E6V3 LOC8030750 PTHR43979:SF1 PRE-MRNA-PROCESSING FACTOR 17 PRE-MRNA-PROCESSING FACTOR 17 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8024608|UniProtKB=A0ACM8DIG4 A0ACM8DIG4 LOC8024608 PTHR45667:SF9 S-ADENOSYLMETHIONINE MITOCHONDRIAL CARRIER PROTEIN MITOCHONDRIAL S-ADENOSYLMETHIONINE CARRIER PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158 IXOSC|EnsemblGenome=LOC8025851|UniProtKB=A0ACM8DT20 A0ACM8DT20 LOC8025851 PTHR11365:SF2 5-OXOPROLINASE RELATED 5-OXOPROLINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8031798|UniProtKB=A0ACM8E3T2 A0ACM8E3T2 Ing5 PTHR10333:SF113 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN 5 histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;histone H3 reader activity#GO:0140006;chromatin-protein adaptor activity#GO:0140463 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121838291|UniProtKB=A0ACM8G7G4 A0ACM8G7G4 LOC121838291 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031476|UniProtKB=A0ACM8EB23 A0ACM8EB23 LOC8031476 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;ornithine decarboxylase activity#GO:0004586;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC8041984|UniProtKB=A0ACM8DKR8 A0ACM8DKR8 LOC8041984 PTHR38640:SF1 GEO09659P1 GEO09659P1 IXOSC|EnsemblGenome=LOC8038141|UniProtKB=A0ACM8FF31 A0ACM8FF31 LOC8038141 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115322420|UniProtKB=A0ACM8EZ71 A0ACM8EZ71 LOC115322420 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837260|UniProtKB=A0ACM8EGX2 A0ACM8EGX2 LOC120837260 PTHR11426:SF263 HISTONE H3 HISTONE H3.X-RELATED mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle fission#GO:0048285;kinetochore organization#GO:0051383;localization#GO:0051179;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121838359|UniProtKB=A0ACM8G7K7 A0ACM8G7K7 LOC121838359 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8052301|UniProtKB=A0ACM8DM15 A0ACM8DM15 LOC8052301 PTHR31715:SF0 UREASE ACCESSORY PROTEIN G UREASE ACCESSORY PROTEIN G enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 metabolic process#GO:0008152;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 IXOSC|EnsemblGenome=LOC8025859|UniProtKB=A0ACM8DGI8 A0ACM8DGI8 LOC8025859 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120837623|UniProtKB=A0ACM8EHD3 A0ACM8EHD3 LOC120837623 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035644|UniProtKB=A0ACM8DJV9 A0ACM8DJV9 Nup44A PTHR11024:SF3 NUCLEAR PORE COMPLEX PROTEIN SEC13 / SEH1 FAMILY MEMBER NUCLEOPORIN SEH1 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of TORC1 signaling#GO:1903432;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of TORC1 signaling#GO:1904263;response to stress#GO:0006950;response to nutrient levels#GO:0031667;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular response to amino acid starvation#GO:0034198;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;Seh1-associated complex#GO:0035859;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear pore outer ring#GO:0031080;nucleus#GO:0005634;organelle envelope#GO:0031967 transporter#PC00227 IXOSC|EnsemblGenome=LOC8024707|UniProtKB=A0ACM8EN83 A0ACM8EN83 LOC8024707 PTHR11690:SF248 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC115312554|UniProtKB=A0ACM8DS84 A0ACM8DS84 PTHR10339:SF32 ADP-RIBOSYLTRANSFERASE ECTO-ADP-RIBOSYLTRANSFERASE 5-RELATED glycosyltransferase activity#GO:0016757;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763 transferase#PC00220 IXOSC|EnsemblGenome=LOC8028511|UniProtKB=A0ACM8DGL2 A0ACM8DGL2 LOC8028511 PTHR11214:SF314 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836172|UniProtKB=A0ACM8FXS3 A0ACM8FXS3 LOC8025658 PTHR45902:SF1 LATROPHILIN RECEPTOR-LIKE PROTEIN A LATROPHILIN RECEPTOR-LIKE PROTEIN A transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115332169|UniProtKB=A0ACM8EYT5 A0ACM8EYT5 LOC115332169 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121833063|UniProtKB=A0ACM8FI27 A0ACM8FI27 LOC121833063 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115325842|UniProtKB=A0ACM8E551 A0ACM8E551 LOC115325842 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115331698|UniProtKB=A0ACM8ECU3 A0ACM8ECU3 LOC115331698 PTHR24171:SF13 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 46 ISOFORM X1 IXOSC|EnsemblGenome=LOC8028239|UniProtKB=A0ACM8DJM6 A0ACM8DJM6 GatA PTHR11895:SF179 TRANSAMIDASE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115322761|UniProtKB=A0ACM8E3K4 A0ACM8E3K4 LOC115322761 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC115319681|UniProtKB=A0ACM8G3F3 A0ACM8G3F3 LOC115319681 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8032270|UniProtKB=A0ACM8DJB3 A0ACM8DJB3 LOC8032270 PTHR14159:SF0 ATAXIN-3-RELATED ATAXIN-3-RELATED deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233 regulation of ERAD pathway#GO:1904292;regulation of cell communication#GO:0010646;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;negative regulation of TOR signaling#GO:0032007;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of response to endoplasmic reticulum stress#GO:1905897;primary metabolic process#GO:0044238;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;protein metabolic process#GO:0019538;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of TORC1 signaling#GO:1903432;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;positive regulation of proteasomal protein catabolic process#GO:1901800;negative regulation of biological process#GO:0048519;regulation of cellular response to stress#GO:0080135;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;proteasomal protein catabolic process#GO:0010498;negative regulation of signal transduction#GO:0009968;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;regulation of protein metabolic process#GO:0051246;negative regulation of TORC1 signaling#GO:1904262;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8027880|UniProtKB=A0ACM8DJG5 A0ACM8DJG5 LOC8027880 PTHR31437:SF1 SREK1IP1 FAMILY MEMBER PROTEIN SREK1IP1 IXOSC|EnsemblGenome=LOC115310905|UniProtKB=A0ACM8FAQ8 A0ACM8FAQ8 LOC115310905 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine-type peptidase activity#GO:0008236 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115317266|UniProtKB=A0ACM8G873 A0ACM8G873 LOC115317266 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115327184|UniProtKB=A0ACM8F041 A0ACM8F041 LOC115327184 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8030353|UniProtKB=A0ACM8EHY9 A0ACM8EHY9 inaE PTHR45792:SF14 DIACYLGLYCEROL LIPASE HOMOLOG-RELATED DIACYLGLYCEROL LIPASE-ALPHA catalytic activity#GO:0003824;lipase activity#GO:0016298;triacylglycerol lipase activity#GO:0004806;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 multicellular organismal process#GO:0032501;acylglycerol metabolic process#GO:0006639;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;developmental process#GO:0032502;neutral lipid catabolic process#GO:0046461;cellular developmental process#GO:0048869;neutral lipid metabolic process#GO:0006638;neurogenesis#GO:0022008;primary metabolic process#GO:0044238;catabolic process#GO:0009056;anatomical structure development#GO:0048856;system development#GO:0048731;long-chain fatty acid metabolic process#GO:0001676;cellular process#GO:0009987;lipid catabolic process#GO:0016042;icosanoid metabolic process#GO:0006690;nervous system development#GO:0007399;metabolic process#GO:0008152;unsaturated fatty acid metabolic process#GO:0033559;multicellular organism development#GO:0007275;acylglycerol catabolic process#GO:0046464;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;arachidonate metabolic process#GO:0019369;cell differentiation#GO:0030154;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;glycerolipid catabolic process#GO:0046503;olefinic compound metabolic process#GO:0120254;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436 cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;dendritic tree#GO:0097447;postsynaptic membrane#GO:0045211;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron projection membrane#GO:0032589;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8043616|UniProtKB=A0ACM8DUS0 A0ACM8DUS0 LOC8043616 PTHR42714:SF9 TRNA MODIFICATION GTPASE GTPBP3 5-TAURINOMETHYLURIDINE-[TRNA] SYNTHASE SUBUNIT GTPB3, MITOCHONDRIAL RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8032718|UniProtKB=A0ACM8EHG3 A0ACM8EHG3 LOC8032718 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC121833909|UniProtKB=A0ACM8FNJ9 A0ACM8FNJ9 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120836731|UniProtKB=A0ACM8G6K7 A0ACM8G6K7 LOC120836731 PTHR11699:SF211 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC121838297|UniProtKB=A0ACM8G8L8 A0ACM8G8L8 LOC121838297 PTHR12708:SF0 DNA POLYMERASE EPSILON SUBUNIT B DNA POLYMERASE EPSILON SUBUNIT 2 DNA synthesis involved in DNA replication#GO:0090592;DNA-templated DNA replication#GO:0006261;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950 epsilon DNA polymerase complex#GO:0008622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 DNA-directed DNA polymerase#PC00018 IXOSC|EnsemblGenome=LOC8038983|UniProtKB=A0ACM8E3E7 A0ACM8E3E7 LOC8038983 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115314089|UniProtKB=A0ACM8F7Q6 A0ACM8F7Q6 LOC115314089 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115324605|UniProtKB=A0ACM8FLI8 A0ACM8FLI8 TfAP-2 PTHR10812:SF17 TRANSCRIPTION FACTOR AP-2 TRANSCRIPTION FACTOR AP-2, ISOFORM D RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cell population proliferation#GO:0042127;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8042759|UniProtKB=A0ACM8EFC4 A0ACM8EFC4 LOC8042759 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8024889|UniProtKB=A0ACM8EAH8 A0ACM8EAH8 LOC8024889 PTHR45702:SF2 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 membrane protein ectodomain proteolysis#GO:0006509;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 IXOSC|EnsemblGenome=LOC115332267|UniProtKB=A0ACM8EDD1 A0ACM8EDD1 LOC115332267 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8031384|UniProtKB=A0ACM8EEE6 A0ACM8EEE6 LOC8031384 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115317788|UniProtKB=A0ACM8FSG5 A0ACM8FSG5 LOC115317788 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8033872|UniProtKB=A0ACM8F2T2 A0ACM8F2T2 LOC8033872 PTHR24258:SF148 SERINE PROTEASE-RELATED PROTEIN MASQUERADE serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8052104|UniProtKB=A0ACM8ER57 A0ACM8ER57 LOC8052104 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 microbody#GO:0042579;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837197|UniProtKB=A0ACM8EGT9 A0ACM8EGT9 LOC120837197 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836203|UniProtKB=A0ACM8F9D7 A0ACM8F9D7 LOC120836203 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120836842|UniProtKB=A0ACM8FVT6 A0ACM8FVT6 LOC120836842 PTHR11733:SF224 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115318280|UniProtKB=A0ACM8FY45 A0ACM8FY45 LOC115318280 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120838176|UniProtKB=A0ACM8EK00 A0ACM8EK00 LOC120838176 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121048220|UniProtKB=A0ACM8FIV3 A0ACM8FIV3 LOC121048220 PTHR10166:SF67 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-1-LIKE passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic cation channel activity#GO:0005261;voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704 transporter#PC00227;voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC115315645|UniProtKB=A0ACM8DVI8 A0ACM8DVI8 Vha44 PTHR10137:SF0 V-TYPE PROTON ATPASE SUBUNIT C V-TYPE PROTON ATPASE SUBUNIT C monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane#GO:0016020;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC8036364|UniProtKB=A0ACM8FZR4 A0ACM8FZR4 LOC8036364 PTHR22625:SF71 PLEXIN PLEXIN-B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;synapse assembly#GO:0007416;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of multicellular organismal process#GO:0051240;regulation of cell shape#GO:0008360;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;regulation of anatomical structure morphogenesis#GO:0022603;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of cell differentiation#GO:0045597;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;positive regulation of cell development#GO:0010720;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;anatomical structure development#GO:0048856;positive regulation of cell projection organization#GO:0031346;synapse organization#GO:0050808;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of cell differentiation#GO:0045595;neuron projection morphogenesis#GO:0048812;positive regulation of developmental process#GO:0051094;regulation of cell migration#GO:0030334;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;regulation of cell development#GO:0060284;positive regulation of cellular process#GO:0048522;axon guidance#GO:0007411;positive regulation of axonogenesis#GO:0050772;positive regulation of cellular component organization#GO:0051130;generation of neurons#GO:0048699;signaling#GO:0023052;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154;regulation of multicellular organismal development#GO:2000026;cellular component organization#GO:0016043;motor neuron axon guidance#GO:0008045;regulation of axonogenesis#GO:0050770;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;system development#GO:0048731;regulation of nervous system development#GO:0051960;regulation of cell motility#GO:2000145;cell communication#GO:0007154;positive regulation of neurogenesis#GO:0050769;regulation of developmental process#GO:0050793;cellular developmental process#GO:0048869;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell adhesion#GO:0007162;axon development#GO:0061564 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115330728|UniProtKB=A0ACM8EC59 A0ACM8EC59 LOC115330728 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840964|UniProtKB=A0ACM8EQA1 A0ACM8EQA1 LOC120840964 PTHR11177:SF144 CHITINASE CHITINASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115316691|UniProtKB=A0ACM8G7S1 A0ACM8G7S1 LOC115316691 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120849232|UniProtKB=A0ACM8FU43 A0ACM8FU43 LOC120849232 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115325638|UniProtKB=A0ACM8E4Y9 A0ACM8E4Y9 LOC115325638 PTHR22872:SF11 BTK-BINDING PROTEIN-RELATED BTB DOMAIN-CONTAINING PROTEIN monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;transport#GO:0006810 IXOSC|EnsemblGenome=LOC115310004|UniProtKB=A0ACM8DP79 A0ACM8DP79 LOC115310004 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041926|UniProtKB=A0ACM8DKT8 A0ACM8DKT8 LOC8041926 PTHR16007:SF15 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B-LIKE IXOSC|EnsemblGenome=LOC8036463|UniProtKB=A0ACM8EAW1 A0ACM8EAW1 LOC8036463 PTHR43943:SF19 DEHYDROGENASE/REDUCTASE (SDR FAMILY) MEMBER 4 DEHYDROGENASE_REDUCTASE 4 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120841388|UniProtKB=A0ACM8G948 A0ACM8G948 LOC120841388 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;microbody#GO:0042579 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8028653|UniProtKB=A0ACM8DN74 A0ACM8DN74 LOC8028653 PTHR16234:SF5 SIMILAR TO HYPOTHETICAL PROTEIN FLJ20508 AFG2-INTERACTING RIBOSOME MATURATION FACTOR intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115309002|UniProtKB=A0ACM8DNA5 A0ACM8DNA5 LOC115309002 PTHR11054:SF0 6-PHOSPHOGLUCONOLACTONASE 6-PHOSPHOGLUCONOLACTONASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;6-phosphogluconolactonase activity#GO:0017057 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide metabolic process#GO:0009117;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;pentose-phosphate shunt#GO:0006098 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120846622|UniProtKB=A0ACM8F210 A0ACM8F210 LOC120846622 PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC120837642|UniProtKB=A0ACM8EIX0 A0ACM8EIX0 LOC120837642 PTHR46289:SF24 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE IXOSC|EnsemblGenome=LOC8023820|UniProtKB=A0ACM8DUH5 A0ACM8DUH5 PTHR12053:SF4 PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED CARBOXYPEPTIDASE Q catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8032976|UniProtKB=A0ACM8G8P3 A0ACM8G8P3 LOC8032976 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220 IXOSC|EnsemblGenome=LOC120842359|UniProtKB=A0ACM8ETK8 A0ACM8ETK8 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8036188|UniProtKB=A0ACM8DVH1 A0ACM8DVH1 eIF3k PTHR13022:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 11 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT K translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307 eukaryotic translation initiation factor 3 complex#GO:0005852;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8027102|UniProtKB=A0ACM8EDS1 A0ACM8EDS1 LOC8027102 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115313041|UniProtKB=A0ACM8DSJ6 A0ACM8DSJ6 LOC115313041 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8028906|UniProtKB=A0ACM8E167 A0ACM8E167 LOC8028906 PTHR12413:SF1 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC121835037|UniProtKB=A0ACM8FSL5 A0ACM8FSL5 LOC121835037 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120844469|UniProtKB=A0ACM8EYV0 A0ACM8EYV0 LOC120844469 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8036209|UniProtKB=A0ACM8EBZ2 A0ACM8EBZ2 LOC8036209 PTHR32546:SF26 G-PROTEIN COUPLED RECEPTOR 158-RELATED SMOG, ISOFORM D transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8037194|UniProtKB=A0ACM8FHQ0 A0ACM8FHQ0 Cda5 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8023713|UniProtKB=A0ACM8E2D5 A0ACM8E2D5 LOC8023713 PTHR11963:SF23 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120849289|UniProtKB=A0ACM8F7F9 A0ACM8F7F9 LOC120849289 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848109|UniProtKB=A0ACM8G0M0 A0ACM8G0M0 LOC120848109 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8053740|UniProtKB=A0ACM8DUJ4 A0ACM8DUJ4 PTHR10681:SF182 THIOREDOXIN PEROXIDASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stress#GO:0006950;homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;catabolic process#GO:0009056;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC115322012|UniProtKB=A0ACM8ESN7 A0ACM8ESN7 LOC115322012 PTHR47221:SF10 FIBRINOGEN ALPHA CHAIN ANGIOPOIETIN-RELATED PROTEIN 3 IXOSC|EnsemblGenome=LOC121046634|UniProtKB=A0ACM8FEC6 A0ACM8FEC6 LOC121046634 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053305|UniProtKB=A0ACM8FTB2 A0ACM8FTB2 LOC8053305 PTHR23235:SF182 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121835001|UniProtKB=A0ACM8FRW5 A0ACM8FRW5 LOC121835001 PTHR11759:SF76 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120839822|UniProtKB=A0ACM8EMV1 A0ACM8EMV1 LOC120839822 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8042767|UniProtKB=A0ACM8E164 A0ACM8E164 LOC8042767 PTHR48041:SF63 ABC TRANSPORTER G FAMILY MEMBER 28 EARLY GENE AT 23, ISOFORM C transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8042328|UniProtKB=A0ACM8FUR3 A0ACM8FUR3 LOC8042328 PTHR11324:SF16 IL16-RELATED PDZ DOMAIN-CONTAINING PROTEIN 2 cytokine#PC00083;interleukin superfamily#PC00128 IXOSC|EnsemblGenome=LOC121834021|UniProtKB=A0ACM8FNN0 A0ACM8FNN0 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8051558|UniProtKB=A0ACM8FEM2 A0ACM8FEM2 LOC8051558 PTHR45904:SF2 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG A RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8035724|UniProtKB=A0ACM8E052 A0ACM8E052 LOC8035724 PTHR11501:SF19 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 cell development#GO:0048468;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of microtubule-based movement#GO:0060632;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;neuron development#GO:0048666;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of microtubule-based process#GO:0032886;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175;organelle organization#GO:0006996;neurogenesis#GO:0022008;microtubule-based process#GO:0007017;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;neuron differentiation#GO:0030182 microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;plasma membrane bounded cell projection#GO:0120025;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;axon#GO:0030424;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC8042575|UniProtKB=A0ACM8DWB6 A0ACM8DWB6 LOC8042575 PTHR22722:SF14 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED MEGALIN, ISOFORM A hormone binding#GO:0042562;binding#GO:0005488 cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 IXOSC|EnsemblGenome=LOC8027201|UniProtKB=A0ACM8F6J6 A0ACM8F6J6 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC120842392|UniProtKB=A0ACM8EUR9 A0ACM8EUR9 LOC120842392 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037875|UniProtKB=A0ACM8FQR8 A0ACM8FQR8 PTHR43160:SF3 ACONITATE HYDRATASE B ACONITATE HYDRATASE, MITOCHONDRIAL lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;iron-sulfur cluster binding#GO:0051536;hydro-lyase activity#GO:0016836;binding#GO:0005488;small molecule binding#GO:0036094;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739 hydratase#PC00120;lyase#PC00144 TCA cycle#P00051>Aconitase#P01268 IXOSC|EnsemblGenome=LOC121834864|UniProtKB=A0ACM8FSM1 A0ACM8FSM1 LOC121834864 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318789|UniProtKB=A0ACM8G896 A0ACM8G896 LOC115318789 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8032206|UniProtKB=A0ACM8EE49 A0ACM8EE49 pasha PTHR13482:SF3 MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8 MICROPROCESSOR COMPLEX SUBUNIT DGCR8 binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;primary miRNA processing#GO:0031053;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8042326|UniProtKB=A0ACM8E354 A0ACM8E354 LOC8042326 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120847470|UniProtKB=A0ACM8G3U4 A0ACM8G3U4 LOC120847470 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330727|UniProtKB=A0ACM8EC68 A0ACM8EC68 PTHR13142:SF1 INNER CENTROMERE PROTEIN INNER CENTROMERE PROTEIN intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;midbody#GO:0030496;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spindle#GO:0005819;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;nucleus#GO:0005634;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8053541|UniProtKB=A0ACM8G5U8 A0ACM8G5U8 LOC8053541 PTHR24072:SF335 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHON-LIKE nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154 cytosol#GO:0005829;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC8027262|UniProtKB=A0ACM8FGF0 A0ACM8FGF0 Mon1 PTHR13027:SF19 SAND PROTEIN-RELATED VACUOLAR FUSION PROTEIN MON1 HOMOLOG molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;guanyl-nucleotide exchange factor complex#GO:0032045;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121838104|UniProtKB=A0ACM8G845 A0ACM8G845 LOC121838104 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115320305|UniProtKB=A0ACM8F0J2 A0ACM8F0J2 LOC115320305 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8050513|UniProtKB=A0ACM8DLA6 A0ACM8DLA6 LOC8050513 PTHR23339:SF98 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE PRL-1 PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein phosphatase#PC00195;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8043100|UniProtKB=A0ACM8DL15 A0ACM8DL15 Nmd3 PTHR12746:SF2 NONSENSE-MEDIATED MRNA DECAY PROTEIN 3 60S RIBOSOMAL EXPORT PROTEIN NMD3 ribosomal large subunit binding#GO:0043023;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;binding#GO:0005488 cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;ribosomal large subunit export from nucleus#GO:0000055;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120848560|UniProtKB=A0ACM8F5V7 A0ACM8F5V7 PTHR44252:SF3 D-ERYTHRULOSE REDUCTASE D-ERYTHRULOSE REDUCTASE-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115310269|UniProtKB=A0ACM8FYH3 A0ACM8FYH3 LOC115310269 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8043537|UniProtKB=A0ACM8E4B9 A0ACM8E4B9 LOC8043537 PTHR24346:SF94 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE STK11 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway by glucose deprivation#P04397>LKB1#P04647 IXOSC|EnsemblGenome=LOC8052227|UniProtKB=A0ACM8DM06 A0ACM8DM06 PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8024391|UniProtKB=A0ACM8DI80 A0ACM8DI80 Dad1 PTHR10705:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;oligosaccharyltransferase complex#GO:0008250;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8034621|UniProtKB=A0ACM8F5P4 A0ACM8F5P4 LOC8034621 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8038255|UniProtKB=A0ACM8EA02 A0ACM8EA02 LOC8038255 PTHR12875:SF3 GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG GOLGI TO ER TRAFFIC PROTEIN 4 HOMOLOG molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;protein insertion into membrane#GO:0051205;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC115328376|UniProtKB=A0ACM8E915 A0ACM8E915 LOC115328376 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC115310694|UniProtKB=A0ACM8DQA6 A0ACM8DQA6 LOC115310694 PTHR21385:SF0 ZINC FINGER PROTEIN-RELATED RE51073P IXOSC|EnsemblGenome=LOC120839111|UniProtKB=A0ACM8EKS3 A0ACM8EKS3 LOC120839111 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8029987|UniProtKB=A0ACM8EAR7 A0ACM8EAR7 LOC8029987 PTHR11699:SF310 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE (NAD(+)) oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 metabolic process#GO:0008152;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;catabolic process#GO:0009056;aldehyde catabolic process#GO:0046185 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC121835587|UniProtKB=A0ACM8FW78 A0ACM8FW78 LOC121835587 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8034954|UniProtKB=A0ACM8FAD8 A0ACM8FAD8 LOC8034954 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8051601|UniProtKB=A0ACM8DW19 A0ACM8DW19 LOC8051601 PTHR10913:SF45 FOLLISTATIN-RELATED AGRIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120837822|UniProtKB=A0ACM8EID2 A0ACM8EID2 LOC120837822 PTHR10041:SF11 COLIPASE SUBFAMILY NOT NAMED protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115327596|UniProtKB=A0ACM8ENC8 A0ACM8ENC8 LOC115327596 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838785|UniProtKB=A0ACM8ELK6 A0ACM8ELK6 LOC120838785 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313846|UniProtKB=A0ACM8DTH7 A0ACM8DTH7 LOC115313846 PTHR12925:SF2 HIKESHI FAMILY MEMBER PROTEIN HIKESHI protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;molecular carrier activity#GO:0140104;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;nucleocytoplasmic carrier activity#GO:0140142;heat shock protein binding#GO:0031072 protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120841031|UniProtKB=A0ACM8EQM8 A0ACM8EQM8 LOC120841031 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115319140|UniProtKB=A0ACM8EMA6 A0ACM8EMA6 LOC115319140 PTHR11210:SF1 RING BOX ANAPHASE-PROMOTING COMPLEX SUBUNIT 11 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of chromosome separation#GO:1905818;positive regulation of cell cycle#GO:0045787;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;protein modification by small protein conjugation#GO:0032446;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of chromosome organization#GO:0033044;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;regulation of mitotic nuclear division#GO:0007088;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of cell cycle phase transition#GO:1901987;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;catabolic process#GO:0009056;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121835688|UniProtKB=A0ACM8FWI8 A0ACM8FWI8 LOC121835688 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8033143|UniProtKB=A0ACM8G0I4 A0ACM8G0I4 LOC8033143 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115332841|UniProtKB=A0ACM8ENE5 A0ACM8ENE5 LOC115332841 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115315202|UniProtKB=A0ACM8EQD5 A0ACM8EQD5 LOC115315202 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120850695|UniProtKB=A0ACM8F9G0 A0ACM8F9G0 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120846389|UniProtKB=A0ACM8F1Z4 A0ACM8F1Z4 LOC120846389 PTHR45920:SF7 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FORMIN-G actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 IXOSC|EnsemblGenome=LOC8035023|UniProtKB=A0ACM8E423 A0ACM8E423 Lar PTHR46957:SF14 CYTOKINE RECEPTOR PROTEIN-TYROSINE-PHOSPHATASE transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8024871|UniProtKB=A0ACM8FMI1 A0ACM8FMI1 PGAP5 PTHR13315:SF0 METALLO PHOSPHOESTERASE RELATED METALLOPHOSPHOESTERASE 1 esterase#PC00097;hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120844631|UniProtKB=A0ACM8FUK0 A0ACM8FUK0 LOC120844631 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846718|UniProtKB=A0ACM8FZK9 A0ACM8FZK9 LOC120846718 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC8033041|UniProtKB=A0ACM8DQI8 A0ACM8DQI8 Hr3 PTHR45805:SF2 NUCLEAR HORMONE RECEPTOR HR3-RELATED NUCLEAR HORMONE RECEPTOR HR3-RELATED transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 IXOSC|EnsemblGenome=LOC115329338|UniProtKB=A0ACM8ENE4 A0ACM8ENE4 LOC115329338 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324209|UniProtKB=A0ACM8FAP3 A0ACM8FAP3 LOC115324209 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8042886|UniProtKB=A0ACM8FE62 A0ACM8FE62 LOC8042886 PTHR14795:SF0 HELICASE RELATED TRANSMEMBRANE PROTEIN 62 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8040673|UniProtKB=A0ACM8FAP0 A0ACM8FAP0 LOC8040673 PTHR10352:SF25 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT G FOUND IN NEURONS, ISOFORM K-RELATED membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8036622|UniProtKB=A0ACM8DP39 A0ACM8DP39 LOC8036622 PTHR23291:SF127 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 1-LIKE passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;endoplasmic reticulum unfolded protein response#GO:0030968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;negative regulation of neuron apoptotic process#GO:0043524;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;response to unfolded protein#GO:0006986;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8024161|UniProtKB=A0ACM8E9Y9 A0ACM8E9Y9 cdc14 PTHR23339:SF129 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE CELL DIVISION CYCLE 14, ISOFORM A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 organelle assembly#GO:0070925;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;regulation of mitotic cell cycle phase transition#GO:1901990;microtubule cytoskeleton organization#GO:0000226;cilium organization#GO:0044782;regulation of cell cycle phase transition#GO:1901987;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell projection assembly#GO:0030031;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;cellular component assembly#GO:0022607;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of cell cycle#GO:0045787 microtubule cytoskeleton#GO:0015630;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8026291|UniProtKB=A0ACM8EBH5 A0ACM8EBH5 LOC8026291 PTHR16509:SF1 FAMILY NOT NAMED MANGANESE-DEPENDENT ADP-RIBOSE_CDP-ALCOHOL DIPHOSPHATASE hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;cation binding#GO:0043169;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity, acting on acid anhydrides#GO:0016817;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112 IXOSC|EnsemblGenome=LOC121835448|UniProtKB=A0ACM8FUR1 A0ACM8FUR1 LOC121835448 PTHR12936:SF0 ANAPHASE-PROMOTING COMPLEX 10 ANAPHASE-PROMOTING COMPLEX SUBUNIT 10 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;cell cycle#GO:0007049;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 ubiquitin-protein ligase#PC00234 Cell cycle#P00013>APC#P00481 IXOSC|EnsemblGenome=LOC8028361|UniProtKB=A0ACM8FNC3 A0ACM8FNC3 PTHR46582:SF1 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 18 IXOSC|EnsemblGenome=LOC121835571|UniProtKB=A0ACM8FW32 A0ACM8FW32 LOC121835571 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115319335|UniProtKB=A0ACM8DZZ6 A0ACM8DZZ6 LOC115319335 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8053119|UniProtKB=A0ACM8DQE7 A0ACM8DQE7 LOC8053119 PTHR24258:SF142 SERINE PROTEASE-RELATED PHENOLOXIDASE-ACTIVATING FACTOR 2 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8027799|UniProtKB=A0ACM8EIN4 A0ACM8EIN4 LOC8027799 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC8032340|UniProtKB=A0ACM8E4D2 A0ACM8E4D2 LOC8032340 PTHR46728:SF1 AN1-TYPE ZINC FINGER PROTEIN 4 AN1-TYPE ZINC FINGER PROTEIN 4 IXOSC|EnsemblGenome=LOC8025569|UniProtKB=A0ACM8DJB7 A0ACM8DJB7 LOC8025569 PTHR34253:SF1 PROTEIN LLP HOMOLOG PROTEIN LLP HOMOLOG anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;developmental cell growth#GO:0048588;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;developmental growth involved in morphogenesis#GO:0060560;neuron development#GO:0048666;neuron projection extension#GO:1990138;anatomical structure development#GO:0048856;cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;growth#GO:0040007;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;developmental growth#GO:0048589;cell growth#GO:0016049;cellular developmental process#GO:0048869 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 IXOSC|EnsemblGenome=LOC120839982|UniProtKB=A0ACM8EP42 A0ACM8EP42 LOC120839982 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120849752|UniProtKB=A0ACM8G4R0 A0ACM8G4R0 LOC120849752 PTHR12642:SF0 RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG RIBOSOME BIOGENESIS PROTEIN NSA2 HOMOLOG rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;preribosome, large subunit precursor#GO:0030687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115328834|UniProtKB=A0ACM8F8A8 A0ACM8F8A8 LOC115328834 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8026471|UniProtKB=A0ACM8DUG4 A0ACM8DUG4 Stam PTHR45929:SF3 JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE JAK PATHWAY SIGNAL TRANSDUCTION ADAPTOR MOLECULE cellular localization#GO:0051641;protein transport#GO:0015031;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;establishment of protein localization to vacuole#GO:0072666;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;endosomal transport#GO:0016197;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;protein metabolic process#GO:0019538;localization#GO:0051179;protein localization to vacuole#GO:0072665;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;macromolecule localization#GO:0033036;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120837093|UniProtKB=A0ACM8EH87 A0ACM8EH87 LOC120837093 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836453|UniProtKB=A0ACM8EF49 A0ACM8EF49 LOC120836453 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038857|UniProtKB=A0ACM8ESM0 A0ACM8ESM0 LOC8038857 PTHR11347:SF111 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE CAMP AND CAMP-INHIBITED CGMP 3',5'-CYCLIC PHOSPHODIESTERASE 10A hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;negative regulation of cellular process#GO:0048523;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057 phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115321040|UniProtKB=A0ACM8FA90 A0ACM8FA90 LOC120851183 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327744|UniProtKB=A0ACM8E7A7 A0ACM8E7A7 LOC115327744 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8043782|UniProtKB=A0ACM8DGY8 A0ACM8DGY8 LOC8043782 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8041793|UniProtKB=A0ACM8F618 A0ACM8F618 LOC8041793 PTHR23345:SF15 VITELLOGENIN-RELATED VITELLOGENIN-6 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 storage protein#PC00210 IXOSC|EnsemblGenome=LOC8028371|UniProtKB=A0ACM8DJQ8 A0ACM8DJQ8 LOC8028371 PTHR21052:SF0 SPERMATOGENESIS ASSOCIATED 11-RELATED RNA DEMETHYLASE ALKBH7, MITOCHONDRIAL oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 IXOSC|EnsemblGenome=LOC120842255|UniProtKB=A0ACM8EUH0 A0ACM8EUH0 mRpS18C PTHR13479:SF40 30S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN BS18M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121837683|UniProtKB=A0ACM8G5M1 A0ACM8G5M1 LOC121837683 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052813|UniProtKB=A0ACM8FIS5 A0ACM8FIS5 LOC8052813 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC120836276|UniProtKB=A0ACM8FJR6 A0ACM8FJR6 LOC120836276 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC121835471|UniProtKB=A0ACM8FU67 A0ACM8FU67 LOC121835471 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115329208|UniProtKB=A0ACM8EAM3 A0ACM8EAM3 LOC115329208 PTHR13832:SF803 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE CG10417-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8023531|UniProtKB=A0ACM8DH81 A0ACM8DH81 Rab35 PTHR47977:SF128 RAS-RELATED PROTEIN RAB LD21953P anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization within membrane#GO:0051668;transport#GO:0006810;intracellular transport#GO:0046907;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8026694|UniProtKB=A0ACM8FWI6 A0ACM8FWI6 LOC8026694 PTHR45700:SF3 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3B ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490 IXOSC|EnsemblGenome=LOC8032962|UniProtKB=A0ACM8DHA1 A0ACM8DHA1 LOC8032962 PTHR13243:SF1 HSPC111 PROTEIN-RELATED NUCLEOLAR PROTEIN 16 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8039084|UniProtKB=A0ACM8E623 A0ACM8E623 LOC8039084 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8036457|UniProtKB=A0ACM8DJZ3 A0ACM8DJZ3 LOC8036457 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;response to heat#GO:0009408;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein metabolic process#GO:0019538;protein refolding#GO:0042026 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC8030151|UniProtKB=A0ACM8DQF4 A0ACM8DQF4 LOC8030151 PTHR11214:SF411 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115328585|UniProtKB=A0ACM8EUV2 A0ACM8EUV2 LOC115328585 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8042917|UniProtKB=A0ACM8DL14 A0ACM8DL14 LOC8042917 PTHR13182:SF8 ZINC FINGER PROTEIN 622 CYTOPLASMIC 60S SUBUNIT BIOGENESIS FACTOR ZNF622 binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273 intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8042876|UniProtKB=A0ACM8DRR8 A0ACM8DRR8 LOC8042876 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121833109|UniProtKB=A0ACM8FJK8 A0ACM8FJK8 LOC121833109 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332498|UniProtKB=A0ACM8EDK4 A0ACM8EDK4 LOC115332498 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837613|UniProtKB=A0ACM8G5K2 A0ACM8G5K2 LOC121837613 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029496|UniProtKB=A0ACM8E0S7 A0ACM8E0S7 LOC8029496 PTHR11999:SF167 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE AROMATIC-L-AMINO-ACID DECARBOXYLASE lyase activity#GO:0016829;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 serotonin metabolic process#GO:0042428;catecholamine metabolic process#GO:0006584;metabolic process#GO:0008152;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;serotonin biosynthetic process#GO:0042427;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958;amine metabolic process#GO:0009308;phenol-containing compound biosynthetic process#GO:0046189 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 lyase#PC00144;decarboxylase#PC00089 Nicotine pharmacodynamics pathway#P06587>DDC#P06608;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961;Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400 IXOSC|EnsemblGenome=LOC8024676|UniProtKB=A0ACM8FMS8 A0ACM8FMS8 PTHR22847:SF751 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase II#GO:0006366;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;Set1C/COMPASS complex#GO:0048188;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;chromosome#GO:0005694;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC121833996|UniProtKB=A0ACM8FP32 A0ACM8FP32 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837363|UniProtKB=A0ACM8G4N1 A0ACM8G4N1 LOC121837363 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328816|UniProtKB=A0ACM8EA37 A0ACM8EA37 LOC115328816 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC121835295|UniProtKB=A0ACM8FTP5 A0ACM8FTP5 LOC121835295 PTHR40380:SF3 FIBRONECTIN TYPE-III DOMAIN-CONTAINING PROTEIN-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115331705|UniProtKB=A0ACM8EZU9 A0ACM8EZU9 LOC115331705 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8040444|UniProtKB=A0ACM8DX36 A0ACM8DX36 LOC8040444 PTHR12131:SF34 ATP-DEPENDENT RNA AND DNA HELICASE SUPERKILLER COMPLEX PROTEIN 2 ATP-dependent activity#GO:0140657;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115320988|UniProtKB=A0ACM8ESL2 A0ACM8ESL2 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120842422|UniProtKB=A0ACM8ETT0 A0ACM8ETT0 LOC120842422 PTHR34072:SF66 ENZYMATIC POLYPROTEIN-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8025543|UniProtKB=A0ACM8DJA4 A0ACM8DJA4 dgt1 PTHR13453:SF1 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 KAT8 REGULATORY NSL COMPLEX SUBUNIT 2 transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115310741|UniProtKB=A0ACM8F584 A0ACM8F584 HBS1 PTHR23115:SF188 TRANSLATION FACTOR HBS1-LIKE PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 gene expression#GO:0010467;biosynthetic process#GO:0009058;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;translational elongation#GO:0006414;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;rescue of stalled cytosolic ribosome#GO:0072344;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;translation#GO:0006412 translation factor#PC00223 IXOSC|EnsemblGenome=LOC115320156|UniProtKB=A0ACM8ENV1 A0ACM8ENV1 Ssl1 PTHR12695:SF2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2 GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 2-RELATED cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;DNA damage response#GO:0006974;transcription by RNA polymerase II#GO:0006366;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170 RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transcription factor TFIIH core complex#GO:0000439;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8029397|UniProtKB=A0ACM8FAN9 A0ACM8FAN9 LOC8029397 PTHR44019:SF24 WD REPEAT-CONTAINING PROTEIN 55 POC1 CENTRIOLAR PROTEIN HOMOLOG cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;cilium#GO:0005929;microtubule organizing center#GO:0005815;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC121835022|UniProtKB=A0ACM8FS25 A0ACM8FS25 LOC121835022 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8024324|UniProtKB=A0ACM8FYJ0 A0ACM8FYJ0 LOC8024324 PTHR19300:SF66 BETA-1,4-GALACTOSYLTRANSFERASE BETA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE A galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120848570|UniProtKB=A0ACM8F601 A0ACM8F601 LOC120848570 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331440|UniProtKB=A0ACM8ED17 A0ACM8ED17 LOC115331440 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8039219|UniProtKB=A0ACM8F642 A0ACM8F642 eco PTHR45884:SF2 N-ACETYLTRANSFERASE ECO N-ACETYLTRANSFERASE ECO catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acyltransferase activity#GO:0140186;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080 chromosome organization#GO:0051276;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;mitotic sister chromatid cohesion#GO:0007064;cellular process#GO:0009987;cell cycle process#GO:0022402;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120847374|UniProtKB=A0ACM8F406 A0ACM8F406 LOC120847374 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC115323577|UniProtKB=A0ACM8EKC3 A0ACM8EKC3 LOC115323577 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8044048|UniProtKB=A0ACM8DL68 A0ACM8DL68 LOC8044048 PTHR28559:SF1 DNA REPAIR PROTEIN XRCC4 RE59279P cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;response to ionizing radiation#GO:0010212;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;response to radiation#GO:0009314;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;DNA repair complex#GO:1990391;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8035209|UniProtKB=A0ACM8FYG9 A0ACM8FYG9 LOC8035209 PTHR31796:SF2 SUZ DOMAIN-CONTAINING PROTEIN 1 SUZ RNA-BINDING DOMAIN-CONTAINING IXOSC|EnsemblGenome=LOC8026683|UniProtKB=A0ACM8DRZ0 A0ACM8DRZ0 LOC8026683 PTHR11652:SF1 30S RIBOSOMAL PROTEIN S12 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US12M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;ribosome#GO:0005840;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115314624|UniProtKB=A0ACM8EN37 A0ACM8EN37 LOC115314624 PTHR24393:SF175 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8040545|UniProtKB=A0ACM8DKK8 A0ACM8DKK8 PCNA PTHR11352:SF0 PROLIFERATING CELL NUCLEAR ANTIGEN DNA SLIDING CLAMP PCNA molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;DNA synthesis involved in DNA replication#GO:0090592;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;DNA replication#GO:0006260;response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA polymerase processivity factor#PC00015 DNA replication#P00017>PCNA#P00534 IXOSC|EnsemblGenome=LOC8053874|UniProtKB=A0ACM8DLP2 A0ACM8DLP2 LOC8053874 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121833475|UniProtKB=A0ACM8FLB5 A0ACM8FLB5 LOC121833475 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121835033|UniProtKB=A0ACM8FS11 A0ACM8FS11 LOC121835033 PTHR23415:SF29 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT-RELATED kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase activator activity#GO:0030295;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;mitotic cell cycle phase transition#GO:0044772;cellular process#GO:0009987;cell cycle process#GO:0022402 intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121046787|UniProtKB=A0ACM8FDL5 A0ACM8FDL5 LOC121046787 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8043364|UniProtKB=A0ACM8FTB6 A0ACM8FTB6 LOC8043364 PTHR47327:SF23 FI18240P1-RELATED FI17836P1 anatomical structure development#GO:0048856;developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653 IXOSC|EnsemblGenome=LOC120839064|UniProtKB=A0ACM8EKM0 A0ACM8EKM0 LOC120839064 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849140|UniProtKB=A0ACM8F839 A0ACM8F839 LOC120849140 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8028588|UniProtKB=A0ACM8G7T2 A0ACM8G7T2 singed PTHR10551:SF9 FASCIN FASCIN-2 actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cellular component organization#GO:0016043;actin filament bundle organization#GO:0061572;actin filament bundle assembly#GO:0051017;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;establishment or maintenance of cell polarity#GO:0007163;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell migration#GO:0016477;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC8037950|UniProtKB=A0ACM8DIE0 A0ACM8DIE0 LOC8037950 PTHR11829:SF377 FORKHEAD BOX PROTEIN FORK HEAD DOMAIN-CONTAINING PROTEIN FD4-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8053089|UniProtKB=A0ACM8E986 A0ACM8E986 LOC8053089 PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8053057|UniProtKB=A0ACM8DLJ8 A0ACM8DLJ8 mRpL45 PTHR28554:SF1 39S RIBOSOMAL PROTEIN L45, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML45 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC121837754|UniProtKB=A0ACM8G6B6 A0ACM8G6B6 LOC121837754 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031811|UniProtKB=A0ACM8DTS2 A0ACM8DTS2 LOC8031811 PTHR15351:SF6 ERLIN (ER LIPID RAFT ASSOCIATED PROTEIN) HOMOLOG ERLIN response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;SREBP signaling pathway#GO:0032933;biological regulation#GO:0065007;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to stimulus#GO:0050896;signaling#GO:0023052;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC115326821|UniProtKB=A0ACM8FT71 A0ACM8FT71 LOC115326821 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120849314|UniProtKB=A0ACM8G8S6 A0ACM8G8S6 LOC120849314 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8033701|UniProtKB=A0ACM8G2D8 A0ACM8G2D8 LOC8033701 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8034183|UniProtKB=A0ACM8DYV3 A0ACM8DYV3 Spt6 PTHR10145:SF6 TRANSCRIPTION ELONGATION FACTOR SPT6 TRANSCRIPTION ELONGATION FACTOR SPT6 protein binding#GO:0005515;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;binding#GO:0005488;histone binding#GO:0042393;chromatin binding#GO:0003682 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;chromatin remodeling#GO:0006338;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115310997|UniProtKB=A0ACM8DQG1 A0ACM8DQG1 LOC115310997 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8026581|UniProtKB=A0ACM8FZD9 A0ACM8FZD9 LOC8026581 PTHR24258:SF147 SERINE PROTEASE-RELATED FI16631P1-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115310230|UniProtKB=A0ACM8DPI3 A0ACM8DPI3 Hsc20 PTHR14021:SF20 IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB IRON-SULFUR CLUSTER CO-CHAPERONE PROTEIN HSCB molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;ATPase activator activity#GO:0001671 iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8035628|UniProtKB=A0ACM8E399 A0ACM8E399 MED20 PTHR12465:SF0 UBIQUITIN SPECIFIC PROTEASE HOMOLOG 49 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 20 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115325873|UniProtKB=A0ACM8E594 A0ACM8E594 LOC115325873 PTHR18934:SF83 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16 isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121835616|UniProtKB=A0ACM8FVX2 A0ACM8FVX2 LOC121835616 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120844767|UniProtKB=A0ACM8FJQ9 A0ACM8FJQ9 LOC120844767 PTHR11214:SF219 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE UDP-GALNAC:BETA-1,3-N-ACETYLGALACTOSAMINYLTRANSFERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120837950|UniProtKB=A0ACM8EJM1 A0ACM8EJM1 LOC120837950 PTHR46174:SF1 CXXC-TYPE ZINC FINGER PROTEIN 1 CXXC-TYPE ZINC FINGER PROTEIN 1 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC8027634|UniProtKB=A0ACM8DTA5 A0ACM8DTA5 LOC8027634 PTHR15615:SF127 FAMILY NOT NAMED PROTEIN CNPPD1 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115311875|UniProtKB=A0ACM8DRP5 A0ACM8DRP5 LOC115311875 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843087|UniProtKB=A0ACM8EV70 A0ACM8EV70 LOC120843087 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030834|UniProtKB=A0ACM8DVP4 A0ACM8DVP4 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC120837930|UniProtKB=A0ACM8EI47 A0ACM8EI47 LOC120837930 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317326|UniProtKB=A0ACM8FCJ4 A0ACM8FCJ4 LOC115317326 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120837589|UniProtKB=A0ACM8G224 A0ACM8G224 LOC120837589 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8034602|UniProtKB=A0ACM8EKA2 A0ACM8EKA2 LOC8034602 PTHR13059:SF10 HMG-BOX TRANSCRIPTION FACTOR BBX HMG BOX TRANSCRIPTION FACTOR BBX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 IXOSC|EnsemblGenome=LOC115324311|UniProtKB=A0ACM8EQT1 A0ACM8EQT1 LOC115324311 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8037210|UniProtKB=A0ACM8EZ64 A0ACM8EZ64 LOC8037210 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8031722|UniProtKB=A0ACM8DIN0 A0ACM8DIN0 LOC8031722 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746 protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;protein sumoylation#GO:0016925;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 IXOSC|EnsemblGenome=LOC8028325|UniProtKB=A0ACM8FY54 A0ACM8FY54 LOC8028325 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8026986|UniProtKB=A0ACM8DXL1 A0ACM8DXL1 LOC8026986 PTHR10858:SF23 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE II hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC8053681|UniProtKB=A0ACM8DYM1 A0ACM8DYM1 PTHR48493:SF1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 UBIQUITIN-LIKE DOMAIN-CONTAINING CTD PHOSPHATASE 1 phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8032124|UniProtKB=A0ACM8EEC8 A0ACM8EEC8 LOC8032124 PTHR21656:SF2 MALE-SPECIFIC LETHAL-1 PROTEIN MALE-SPECIFIC LETHAL 1 HOMOLOG chromatin binding#GO:0003682;binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8052263|UniProtKB=A0ACM8DM10 A0ACM8DM10 LOC8052263 PTHR32121:SF0 PCNA-INTERACTING PARTNER PCNA-INTERACTING PARTNER regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of DNA recombination#GO:0045910;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;negative regulation of double-strand break repair via homologous recombination#GO:2000042;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694 IXOSC|EnsemblGenome=LOC8040502|UniProtKB=A0ACM8EQA3 A0ACM8EQA3 LOC8040502 PTHR23326:SF35 CCR4 NOT-RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;P-body#GO:0000932;intracellular organelle#GO:0043229;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;CCR4-NOT complex#GO:0030014 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8044157|UniProtKB=A0ACM8E004 A0ACM8E004 LOC8044157 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8043563|UniProtKB=A0ACM8DVQ8 A0ACM8DVQ8 LOC8043563 PTHR17695:SF11 SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG SMALL SUBUNIT PROCESSOME COMPONENT 20 HOMOLOG RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC8024741|UniProtKB=A0ACM8DXY2 A0ACM8DXY2 PTHR14131:SF5 ANOSMIN ANOSMIN-1 cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;developmental process#GO:0032502;generation of neurons#GO:0048699;neuron differentiation#GO:0030182;animal gross anatomical part developmental process#GO:0160108;neurogenesis#GO:0022008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8026468|UniProtKB=A0ACM8EJU5 A0ACM8EJU5 LOC8026468 PTHR11690:SF248 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8030296|UniProtKB=A0ACM8DWY2 A0ACM8DWY2 LOC8030296 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115327405|UniProtKB=A0ACM8EUW8 A0ACM8EUW8 LOC115327405 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034968|UniProtKB=A0ACM8FNJ6 A0ACM8FNJ6 LOC8034968 PTHR13434:SF0 PROTEIN CASC3 PROTEIN CASC3 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115319001|UniProtKB=A0ACM8ERX9 A0ACM8ERX9 LOC115319001 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC120837990|UniProtKB=A0ACM8EIS5 A0ACM8EIS5 LOC120837990 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052077|UniProtKB=A0ACM8DUS6 A0ACM8DUS6 LOC8052077 PTHR10071:SF340 TRANSCRIPTION FACTOR GATA FAMILY MEMBER FI19405P1-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;cell fate commitment#GO:0045165;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8053138|UniProtKB=A0ACM8DLZ7 A0ACM8DLZ7 LOC8053138 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC115328780|UniProtKB=A0ACM8EZV8 A0ACM8EZV8 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121832985|UniProtKB=A0ACM8FSM6 A0ACM8FSM6 LOC121832985 PTHR46150:SF3 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN 100F enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell migration#GO:0016477;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of Ras protein signal transduction#GO:0046578;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 membrane#GO:0016020;cell periphery#GO:0071944;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120844318|UniProtKB=A0ACM8FKX6 A0ACM8FKX6 LOC120844318 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC115323637|UniProtKB=A0ACM8FZM1 A0ACM8FZM1 LOC115323637 PTHR46599:SF9 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED 4-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115326195|UniProtKB=A0ACM8ETG8 A0ACM8ETG8 LOC115326195 PTHR20852:SF57 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE 2 CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 IXOSC|EnsemblGenome=LOC8033546|UniProtKB=A0ACM8DTE2 A0ACM8DTE2 LOC8033546 PTHR10060:SF48 TATD FAMILY DEOXYRIBONUCLEASE DEOXYRIBONUCLEASE TATDN1 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121046777|UniProtKB=A0ACM8FFT4 A0ACM8FFT4 LOC121046777 PTHR37984:SF33 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1-RELATED IXOSC|EnsemblGenome=LOC8050485|UniProtKB=A0ACM8DLF1 A0ACM8DLF1 PTHR12377:SF0 CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B-RELATED CYTOSOLIC IRON-SULFUR ASSEMBLY COMPONENT 2B biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120847882|UniProtKB=A0ACM8FT19 A0ACM8FT19 LOC120847882 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC121833057|UniProtKB=A0ACM8FJC7 A0ACM8FJC7 IFT46 PTHR13376:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 46 HOMOLOG plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;motile cilium#GO:0031514;cellular anatomical structure#GO:0110165;cilium#GO:0005929;intracellular organelle#GO:0043229;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8029277|UniProtKB=A0ACM8EDH4 A0ACM8EDH4 LOC8029277 PTHR45788:SF4 SUCCINATE/FUMARATE MITOCHONDRIAL TRANSPORTER-RELATED TRICARBOXYLATE TRANSPORT PROTEIN, MITOCHONDRIAL active transmembrane transporter activity#GO:0022804;citrate transmembrane transporter activity#GO:0015137;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 cellular process#GO:0009987;carboxylic acid transmembrane transport#GO:1905039;citrate transport#GO:0015746;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;tricarboxylic acid transport#GO:0006842;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 transporter#PC00227 IXOSC|EnsemblGenome=LOC8035932|UniProtKB=A0ACM8DVH8 A0ACM8DVH8 LOC8035932 PTHR11256:SF50 BCL-2 RELATED APOPTOSIS REGULATOR CED-9 channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;signaling#GO:0023052;extrinsic apoptotic signaling pathway#GO:0097191;response to stimulus#GO:0050896;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;cell surface receptor signaling pathway#GO:0007166;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;cell death#GO:0008219;programmed cell death#GO:0012501;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522 organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;mitochondrial outer membrane#GO:0005741;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC120845252|UniProtKB=A0ACM8G6S5 A0ACM8G6S5 LOC120845252 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121836492|UniProtKB=A0ACM8FZU0 A0ACM8FZU0 LOC121836492 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841078|UniProtKB=A0ACM8EQG8 A0ACM8EQG8 LOC120841078 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8038712|UniProtKB=A0ACM8G0K6 A0ACM8G0K6 LOC8038712 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115314294|UniProtKB=A0ACM8EV16 A0ACM8EV16 LOC115314294 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8032085|UniProtKB=A0ACM8E666 A0ACM8E666 l(2)k09022 PTHR13457:SF1 BAP28 HEAT REPEAT-CONTAINING PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515 positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of transcription by RNA polymerase I#GO:0006356;positive regulation of transcription by RNA polymerase I#GO:0045943;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 organelle lumen#GO:0043233;mitochondrion#GO:0005739;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120839145|UniProtKB=A0ACM8ELK5 A0ACM8ELK5 LOC120839145 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842675|UniProtKB=A0ACM8EVE9 A0ACM8EVE9 LOC120842675 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115331629|UniProtKB=A0ACM8EDK5 A0ACM8EDK5 LOC115331629 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8052299|UniProtKB=A0ACM8DYA0 A0ACM8DYA0 LOC8052299 PTHR14390:SF2 G PATCH DOMAIN CONTAINING PROTEIN 3 G PATCH DOMAIN-CONTAINING PROTEIN 3 ISOFORM X1 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355 IXOSC|EnsemblGenome=LOC120846815|UniProtKB=A0ACM8G664 A0ACM8G664 CASK PTHR23122:SF7 MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK PERIPHERAL PLASMA MEMBRANE PROTEIN CASK protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 intracellular protein localization#GO:0008104;regulation of localization#GO:0032879;regulation of transport#GO:0051049;macromolecule localization#GO:0033036;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;localization#GO:0051179;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of neurotransmitter secretion#GO:0046928;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>CASK#P01232;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>CaMK#P00847 IXOSC|EnsemblGenome=LOC115332825|UniProtKB=A0ACM8G1J1 A0ACM8G1J1 LOC115332825 PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN catalytic activity, acting on RNA#GO:0140098;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 RNA metabolic process#GO:0016070;RNA decapping#GO:0110154;RNA catabolic process#GO:0006401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8032693|UniProtKB=A0ACM8E7L2 A0ACM8E7L2 LOC8032693 PTHR14381:SF1 DACTYLIN F-BOX_WD REPEAT-CONTAINING PROTEIN 4 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 response to stimulus#GO:0050896;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;protein metabolic process#GO:0019538;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA damage response#GO:0006974 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;transferase complex#GO:1990234;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC8051886|UniProtKB=A0ACM8FU14 A0ACM8FU14 LOC8051886 PTHR23025:SF3 TRIACYLGLYCEROL LIPASE HORMONE-SENSITIVE LIPASE hydrolase activity#GO:0016787;triacylglycerol lipase activity#GO:0004806;lipase activity#GO:0016298;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;glycerolipid metabolic process#GO:0046486;lipid catabolic process#GO:0016042;cellular process#GO:0009987;primary metabolic process#GO:0044238;acylglycerol catabolic process#GO:0046464;neutral lipid metabolic process#GO:0006638;neutral lipid catabolic process#GO:0046461;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;triglyceride catabolic process#GO:0019433;glycerolipid catabolic process#GO:0046503;acylglycerol metabolic process#GO:0006639 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 Triacylglycerol metabolism#P02782>Triacylglycerol lipase#P03205 IXOSC|EnsemblGenome=LOC115324928|UniProtKB=A0ACM8EPK9 A0ACM8EPK9 LOC115324928 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030408|UniProtKB=A0ACM8DWY9 A0ACM8DWY9 LOC8030408 PTHR31259:SF3 ENDOSOME-ASSOCIATED TRAFFICKING REGULATOR 1 ENDOSOME-ASSOCIATED-TRAFFICKING REGULATOR 1 regulation of cellular process#GO:0050794;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;centrosome#GO:0005813;recycling endosome#GO:0055037;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;endomembrane system#GO:0012505;microtubule cytoskeleton#GO:0015630;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;midbody#GO:0030496 IXOSC|EnsemblGenome=LOC8038341|UniProtKB=A0ACM8DK60 A0ACM8DK60 LOC8038341 PTHR11538:SF41 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8041998|UniProtKB=A0ACM8DKU9 A0ACM8DKU9 viaf PTHR45809:SF3 VIRAL IAP-ASSOCIATED FACTOR HOMOLOG PHOSDUCIN-LIKE PROTEIN 2 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8051873|UniProtKB=A0ACM8EA88 A0ACM8EA88 LOC8051873 PTHR46957:SF3 CYTOKINE RECEPTOR PROTEIN-TYROSINE-PHOSPHATASE transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8051751|UniProtKB=A0ACM8EQS1 A0ACM8EQS1 LOC8051751 PTHR24171:SF15 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50-RELATED IXOSC|EnsemblGenome=LOC121837951|UniProtKB=A0ACM8G5J3 A0ACM8G5J3 LOC121837951 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8032122|UniProtKB=A0ACM8DQU7 A0ACM8DQU7 TTLL12 PTHR46088:SF1 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 TUBULIN--TYROSINE LIGASE-LIKE PROTEIN 12 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115331656|UniProtKB=A0ACM8FR35 A0ACM8FR35 LOC115331656 PTHR11732:SF482 ALDO/KETO REDUCTASE LD24679P oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053550|UniProtKB=A0ACM8ECJ3 A0ACM8ECJ3 Vps52 PTHR14190:SF16 SUPPRESSOR OF ACTIN MUTATIONS 2/VACUOLAR PROTEIN SORTING 52 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 52 HOMOLOG protein binding#GO:0005515;syntaxin binding#GO:0019905;binding#GO:0005488;SNARE binding#GO:0000149 cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;lysosomal transport#GO:0007041;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8031790|UniProtKB=A0ACM8DSJ5 A0ACM8DSJ5 LOC8031790 PTHR12496:SF0 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC120850680|UniProtKB=A0ACM8FAU4 A0ACM8FAU4 LOC120850680 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC115312063|UniProtKB=A0ACM8FL40 A0ACM8FL40 LOC115312063 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121835821|UniProtKB=A0ACM8FX29 A0ACM8FX29 LOC121835821 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322215|UniProtKB=A0ACM8G252 A0ACM8G252 LOC115322215 PTHR11610:SF200 LIPASE FI22312P1 catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8034225|UniProtKB=A0ACM8DJ42 A0ACM8DJ42 RpS19a PTHR11710:SF0 40S RIBOSOMAL PROTEIN S19 SMALL RIBOSOMAL SUBUNIT PROTEIN ES19 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8034859|UniProtKB=A0ACM8DT40 A0ACM8DT40 RabX6 PTHR24073:SF1249 DRAB5-RELATED RABX6, ISOFORM B hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 organelle#GO:0043226;endomembrane system#GO:0012505;late endosome#GO:0005770;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC121832905|UniProtKB=A0ACM8FV62 A0ACM8FV62 LOC121832905 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115311069|UniProtKB=A0ACM8EU21 A0ACM8EU21 LOC115311069 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115309545|UniProtKB=A0ACM8EGI5 A0ACM8EGI5 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053963|UniProtKB=A0ACM8FU48 A0ACM8FU48 LOC8053963 PTHR24379:SF125 KRAB AND ZINC FINGER DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121834821|UniProtKB=A0ACM8FQ87 A0ACM8FQ87 LOC121834821 PTHR11538:SF41 PHENYLALANYL-TRNA SYNTHETASE PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC121837940|UniProtKB=A0ACM8G5U9 A0ACM8G5U9 LOC121837940 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8052253|UniProtKB=A0ACM8EBN8 A0ACM8EBN8 LOC8052253 PTHR12420:SF50 PHD FINGER PROTEIN LD43541P-RELATED intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115324082|UniProtKB=A0ACM8EH06 A0ACM8EH06 LOC115324082 PTHR11662:SF462 SOLUTE CARRIER FAMILY 17 FI19708P1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115312061|UniProtKB=A0ACM8FK09 A0ACM8FK09 LOC115312061 PTHR22730:SF1 PROMININ PROM PROTEIN PROMININ-LIKE PROTEIN plasma membrane bounded cell projection organization#GO:0120036;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;apical plasma membrane#GO:0016324;actin cytoskeleton#GO:0015629;microvillus#GO:0005902;actin-based cell projection#GO:0098858;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;cilium#GO:0005929;intracellular organelle#GO:0043229;plasma membrane region#GO:0098590;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;apical part of cell#GO:0045177 IXOSC|EnsemblGenome=LOC8034576|UniProtKB=A0ACM8E9J4 A0ACM8E9J4 LOC8034576 PTHR10337:SF11 SHC TRANSFORMING PROTEIN DSHC PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of cell population proliferation#GO:0008284 scaffold/adaptor protein#PC00226 PDGF signaling pathway#P00047>Shc#P01175;FGF signaling pathway#P00021>Shc#P00639;Integrin signalling pathway#P00034>Shc#P00949;EGF receptor signaling pathway#P00018>Shc#P00554 IXOSC|EnsemblGenome=LOC120846903|UniProtKB=A0ACM8F2Q0 A0ACM8F2Q0 LOC120846903 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC120838782|UniProtKB=A0ACM8EKH4 A0ACM8EKH4 LOC120838782 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;circulatory system development#GO:0072359;heart development#GO:0007507;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120842291|UniProtKB=A0ACM8ETE8 A0ACM8ETE8 LOC120842291 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026414|UniProtKB=A0ACM8DHR8 A0ACM8DHR8 ND-B14.5B PTHR13099:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B14.5B NADH DEHYDROGENASE [UBIQUINONE] 1 SUBUNIT C2-RELATED respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8023481|UniProtKB=A0ACM8DPP6 A0ACM8DPP6 LOC8023481 PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8031572|UniProtKB=A0ACM8EU70 A0ACM8EU70 LOC8031572 PTHR10741:SF2 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC121836656|UniProtKB=A0ACM8FZL2 A0ACM8FZL2 LOC121836656 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8024727|UniProtKB=A0ACM8E054 A0ACM8E054 LOC8024727 PTHR24305:SF166 CYTOCHROME P450 CYTOCHROME P450 302A1, MITOCHONDRIAL-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115309644|UniProtKB=A0ACM8FQC6 A0ACM8FQC6 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC120847465|UniProtKB=A0ACM8FPE4 A0ACM8FPE4 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025862|UniProtKB=A0ACM8DQG0 A0ACM8DQG0 LOC8025862 PTHR11426:SF287 HISTONE H3 HISTONE H3.3A-RELATED cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;kinetochore assembly#GO:0051382;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle assembly#GO:0070925;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;chromosome localization#GO:0050000;cellular component assembly#GO:0022607;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 IXOSC|EnsemblGenome=LOC120847344|UniProtKB=A0ACM8G5A1 A0ACM8G5A1 LOC120847344 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121047507|UniProtKB=A0ACM8FGH3 A0ACM8FGH3 LOC121047507 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115317043|UniProtKB=A0ACM8DWQ2 A0ACM8DWQ2 LOC115317043 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120842851|UniProtKB=A0ACM8FQH9 A0ACM8FQH9 PTHR33562:SF27 ATILLA, ISOFORM B-RELATED-RELATED FI02817P-RELATED IXOSC|EnsemblGenome=LOC120843341|UniProtKB=A0ACM8EVW8 A0ACM8EVW8 LOC120843341 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332668|UniProtKB=A0ACM8EEG2 A0ACM8EEG2 LOC115332668 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038710|UniProtKB=A0ACM8E7V3 A0ACM8E7V3 LOC8038710 PTHR46603:SF1 ABSCISSION/NOCUT CHECKPOINT REGULATOR ABSCISSION_NOCUT CHECKPOINT REGULATOR phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;midbody#GO:0030496;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;cleavage furrow#GO:0032154;membraneless organelle#GO:0043228;cell periphery#GO:0071944;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;plasma membrane region#GO:0098590 IXOSC|EnsemblGenome=LOC8052219|UniProtKB=A0ACM8DM19 A0ACM8DM19 LOC8052219 PTHR11071:SF602 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE H organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8024886|UniProtKB=A0ACM8EA58 A0ACM8EA58 LOC8024886 PTHR44313:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 DNAJ HOMOLOG SUBFAMILY C MEMBER 17 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;protein-containing complex disassembly#GO:0032984;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120836482|UniProtKB=A0ACM8EET2 A0ACM8EET2 LOC120836482 PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8024158|UniProtKB=A0ACM8DI05 A0ACM8DI05 LOC8024158 PTHR19818:SF166 ZINC FINGER PROTEIN ZIC AND GLI C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8038199|UniProtKB=A0ACM8DGP4 A0ACM8DGP4 LOC8038199 PTHR11595:SF21 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-DELTA guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC120842252|UniProtKB=A0ACM8ETD1 A0ACM8ETD1 LOC120842252 PTHR45791:SF1 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 1 metal ion binding#GO:0046872;magnesium ion binding#GO:0000287;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509 IXOSC|EnsemblGenome=LOC8034693|UniProtKB=A0ACM8DZN7 A0ACM8DZN7 mTTF PTHR15437:SF6 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676 IXOSC|EnsemblGenome=LOC121834029|UniProtKB=A0ACM8FNZ1 A0ACM8FNZ1 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;homologous recombination#GO:0035825;reproductive process#GO:0022414;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;cell cycle process#GO:0022402;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120844664|UniProtKB=A0ACM8EYY3 A0ACM8EYY3 LOC120844664 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8044006|UniProtKB=A0ACM8FQL9 A0ACM8FQL9 LOC8044006 PTHR46439:SF1 CYSTEINE-RICH MOTOR NEURON 1 PROTEIN CYSTEINE-RICH MOTOR NEURON 1 PROTEIN IXOSC|EnsemblGenome=LOC115328053|UniProtKB=A0ACM8EFI7 A0ACM8EFI7 LOC115328053 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8041283|UniProtKB=A0ACM8ECV9 A0ACM8ECV9 LanB1 PTHR10574:SF375 NETRIN/LAMININ-RELATED LAMININ SUBUNIT BETA-1 cell motility#GO:0048870;system development#GO:0048731;external encapsulating structure organization#GO:0045229;cell-substrate adhesion#GO:0031589;extracellular matrix organization#GO:0030198;anatomical structure development#GO:0048856;plasma membrane bounded cell projection organization#GO:0120036;cell migration#GO:0016477;multicellular organismal process#GO:0032501;tissue development#GO:0009888;extracellular matrix assembly#GO:0085029;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;axonogenesis#GO:0007409;neuron development#GO:0048666;cell adhesion#GO:0007155;generation of neurons#GO:0048699;extracellular structure organization#GO:0043062;animal gross anatomical part developmental process#GO:0160108;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cellular component assembly#GO:0022607;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;substrate adhesion-dependent cell spreading#GO:0034446;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039 extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;basement membrane#GO:0005604;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 IXOSC|EnsemblGenome=LOC115327765|UniProtKB=A0ACM8E8C7 A0ACM8E8C7 LOC115327765 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8034152|UniProtKB=A0ACM8DJ09 A0ACM8DJ09 LOC8034152 PTHR13605:SF4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 7 ENDOPLASMIC RETICULUM MEMBRANE PROTEIN COMPLEX SUBUNIT 7 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;EMC complex#GO:0072546;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8034172|UniProtKB=A0ACM8DR95 A0ACM8DR95 LOC8034172 PTHR45883:SF2 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 IXOSC|EnsemblGenome=LOC8033703|UniProtKB=A0ACM8G0G5 A0ACM8G0G5 LOC8033703 PTHR12411:SF917 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L, LIKE-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115311530|UniProtKB=A0ACM8DR47 A0ACM8DR47 LOC115311530 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833491|UniProtKB=A0ACM8FJZ6 A0ACM8FJZ6 LOC121833491 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043725|UniProtKB=A0ACM8EY23 A0ACM8EY23 LOC8043725 PTHR11920:SF512 GUANYLYL CYCLASE RECEPTOR-TYPE GUANYLATE CYCLASE GCY-28 molecular transducer activity#GO:0060089;lyase activity#GO:0016829;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 lyase#PC00144;guanylate cyclase#PC00114 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581 IXOSC|EnsemblGenome=LOC8052116|UniProtKB=A0ACM8FAM8 A0ACM8FAM8 GlyS PTHR10176:SF3 GLYCOGEN SYNTHASE GLYCOGEN [STARCH] SYNTHASE glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucosyltransferase activity#GO:0046527;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758 carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycogen biosynthetic process#GO:0005978;generation of precursor metabolites and energy#GO:0006091;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;glucan biosynthetic process#GO:0009250;energy reserve metabolic process#GO:0006112;polysaccharide biosynthetic process#GO:0000271 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121835660|UniProtKB=A0ACM8FWE5 A0ACM8FWE5 LOC121835660 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115317866|UniProtKB=A0ACM8F3E4 A0ACM8F3E4 LOC115317866 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312585|UniProtKB=A0ACM8EGP4 A0ACM8EGP4 LOC115312585 PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8029117|UniProtKB=A0ACM8FPJ6 A0ACM8FPJ6 PTHR11959:SF16 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115330335|UniProtKB=A0ACM8EAT9 A0ACM8EAT9 LOC115330335 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035598|UniProtKB=A0ACM8E6R7 A0ACM8E6R7 SCCRO4 PTHR12281:SF12 RP42 RELATED DCN1-LIKE PROTEIN 4 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;binding#GO:0005488;protein binding#GO:0005515;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein metabolic process#GO:0051247;regulation of protein modification process#GO:0031399;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120838739|UniProtKB=A0ACM8EKJ1 A0ACM8EKJ1 Uba4 PTHR10953:SF254 UBIQUITIN-ACTIVATING ENZYME E1 ADENYLYLTRANSFERASE AND SULFURTRANSFERASE MOCS3 catalytic activity, acting on a protein#GO:0140096;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity#GO:0016874;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657 RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;protein modification by small protein conjugation#GO:0032446;tRNA wobble position uridine thiolation#GO:0002143;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;macromolecule modification#GO:0043412;tRNA thio-modification#GO:0034227;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;protein modification by small protein conjugation or removal#GO:0070647;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;post-translational protein modification#GO:0043687;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8051403|UniProtKB=A0ACM8E7N0 A0ACM8E7N0 Fur2 PTHR42884:SF35 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN-LIKE PROTEASE 2 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;regulation of biological quality#GO:0065008;proteolysis#GO:0006508;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cellular process#GO:0009987;peptide hormone processing#GO:0016486;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;Endothelin signaling pathway#P00019>furin#P00575;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 IXOSC|EnsemblGenome=LOC121836758|UniProtKB=A0ACM8G0D5 A0ACM8G0D5 LOC121836758 PTHR45702:SF2 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 IXOSC|EnsemblGenome=LOC121837274|UniProtKB=A0ACM8G4C2 A0ACM8G4C2 LOC121837274 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120840302|UniProtKB=A0ACM8FTY9 A0ACM8FTY9 LOC120840302 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8028186|UniProtKB=A0ACM8E489 A0ACM8E489 LOC8028186 PTHR11923:SF117 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 SENSORY NEURON MEMBRANE PROTEIN 2 cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8035713|UniProtKB=A0ACM8E7X0 A0ACM8E7X0 Vps24 PTHR10476:SF1 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 3 protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;late endosome to vacuole transport#GO:0045324;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8037886|UniProtKB=A0ACM8DYK7 A0ACM8DYK7 LOC8037886 PTHR32315:SF3 ADENINE PHOSPHORIBOSYLTRANSFERASE ADENINE PHOSPHORIBOSYLTRANSFERASE cation binding#GO:0043169;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine nucleobase metabolic process#GO:0006144;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220 Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphoribosyl transferase#P02810 IXOSC|EnsemblGenome=LOC8031468|UniProtKB=A0ACM8ESG1 A0ACM8ESG1 LOC8031468 PTHR46042:SF1 DIPHTHINE METHYLTRANSFERASE DIPHTHINE METHYLTRANSFERASE macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC121047971|UniProtKB=A0ACM8G3G8 A0ACM8G3G8 LOC121047971 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121837285|UniProtKB=A0ACM8G342 A0ACM8G342 LOC121837285 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8034586|UniProtKB=A0ACM8DJH8 A0ACM8DJH8 LOC8034586 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC120841079|UniProtKB=A0ACM8EQX6 A0ACM8EQX6 LOC120841079 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121836676|UniProtKB=A0ACM8G0V3 A0ACM8G0V3 LOC121836676 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC121046682|UniProtKB=A0ACM8G4I1 A0ACM8G4I1 LOC121046682 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121836081|UniProtKB=A0ACM8FY21 A0ACM8FY21 LOC121836081 PTHR16023:SF0 TAX1 BINDING PROTEIN-RELATED PROTEIN VAC14 HOMOLOG organophosphate biosynthetic process#GO:0090407;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;endosome membrane#GO:0010008;endosome#GO:0005768;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8039012|UniProtKB=A0ACM8DMU1 A0ACM8DMU1 LOC8039012 PTHR12607:SF12 ADENOMATOUS POLYPOSIS COLI PROTEIN FAMILY ADENOMATOUS POLYPOSIS COLI PROTEIN-LIKE ISOFORM X1 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of cellular component organization#GO:0051128;regulation of Wnt signaling pathway#GO:0030111;animal gross anatomical part developmental process#GO:0160108;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;cell fate commitment#GO:0045165;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of microtubule cytoskeleton organization#GO:0070507;nervous system development#GO:0007399;negative regulation of signal transduction#GO:0009968;cell fate specification#GO:0001708;multicellular organism development#GO:0007275;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cell communication#GO:0010646;regulation of microtubule-based process#GO:0032886;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;system development#GO:0048731;cell migration#GO:0016477;negative regulation of Wnt signaling pathway#GO:0030178;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of protein depolymerization#GO:1901879 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasmic microtubule#GO:0005881;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;intracellular protein-containing complex#GO:0140535;cytoskeleton#GO:0005856 IXOSC|EnsemblGenome=LOC121048689|UniProtKB=A0ACM8FJ05 A0ACM8FJ05 LOC121048689 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025297|UniProtKB=A0ACM8E2F4 A0ACM8E2F4 WDR79 PTHR13211:SF1 TELOMERASE CAJAL BODY PROTEIN 1 TELOMERASE CAJAL BODY PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC115319628|UniProtKB=A0ACM8DZC2 A0ACM8DZC2 LOC115319628 PTHR23074:SF19 AAA DOMAIN-CONTAINING KATANIN P60 ATPASE-CONTAINING SUBUNIT A1 hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;isomerase activity#GO:0016853;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity, acting on a protein#GO:0140096;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC115321803|UniProtKB=A0ACM8E218 A0ACM8E218 LOC115321803 PTHR12283:SF5 GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE GLUTAMINYL-PEPTIDE CYCLOTRANSFERASE aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;zinc ion binding#GO:0008270;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;binding#GO:0005488;small molecule binding#GO:0036094;acyltransferase activity#GO:0016746;ion binding#GO:0043167 transferase#PC00220 IXOSC|EnsemblGenome=LOC8053042|UniProtKB=A0ACM8DPY9 A0ACM8DPY9 LOC8053042 PTHR45919:SF1 GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE GDP-MAN:MAN(3)GLCNAC(2)-PP-DOL ALPHA-1,2-MANNOSYLTRANSFERASE mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115308197|UniProtKB=A0ACM8EP18 A0ACM8EP18 LOC115308197 PTHR45656:SF18 PROTEIN CBR-CLEC-78 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8033156|UniProtKB=A0ACM8EE77 A0ACM8EE77 LOC8033156 PTHR48465:SF1 PROTEIN SSUH2 HOMOLOG PROTEIN SSUH2 HOMOLOG IXOSC|EnsemblGenome=LOC8023320|UniProtKB=A0ACM8E6G4 A0ACM8E6G4 PTHR14146:SF4 EXOCYST COMPLEX COMPONENT 4 EXOCYST COMPLEX COMPONENT 4 establishment of localization#GO:0051234;exocytosis#GO:0006887;transport#GO:0006810;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;cellular process#GO:0009987;secretion#GO:0046903;cell communication#GO:0007154;localization#GO:0051179;secretion by cell#GO:0032940;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;export from cell#GO:0140352;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;exocyst#GO:0000145;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;cell junction#GO:0030054;cell cortex#GO:0005938;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;growth cone#GO:0030426;axon#GO:0030424;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115325769|UniProtKB=A0ACM8EK46 A0ACM8EK46 LOC115325769 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033970|UniProtKB=A0ACM8DIN1 A0ACM8DIN1 LOC8033970 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8035998|UniProtKB=A0ACM8DH38 A0ACM8DH38 LOC8035998 PTHR43721:SF36 ELONGATION FACTOR TU-RELATED ELONGATION FACTOR TU, MITOCHONDRIAL translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC8038246|UniProtKB=A0ACM8DGS8 A0ACM8DGS8 vnc PTHR23091:SF4 N-TERMINAL ACETYLTRANSFERASE N-TERMINAL AMINO-ACID N(ALPHA)-ACETYLTRANSFERASE NATA N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493 acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC8033431|UniProtKB=A0ACM8DHX9 A0ACM8DHX9 LOC8033431 PTHR46282:SF2 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115332201|UniProtKB=A0ACM8F3K5 A0ACM8F3K5 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332423|UniProtKB=A0ACM8EEJ8 A0ACM8EEJ8 LOC115332423 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8039502|UniProtKB=A0ACM8DT87 A0ACM8DT87 LOC8039502 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8050715|UniProtKB=A0ACM8EGU1 A0ACM8EGU1 LOC8050715 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8043328|UniProtKB=A0ACM8DVR1 A0ACM8DVR1 LOC8043328 PTHR14969:SF13 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE AT30094P phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115332591|UniProtKB=A0ACM8FMM6 A0ACM8FMM6 LOC115332591 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319842|UniProtKB=A0ACM8G146 A0ACM8G146 LOC115319842 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC115326747|UniProtKB=A0ACM8E7T4 A0ACM8E7T4 LOC115326747 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850690|UniProtKB=A0ACM8FAI4 A0ACM8FAI4 LOC120850690 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC120841586|UniProtKB=A0ACM8ERL1 A0ACM8ERL1 LOC120841586 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052388|UniProtKB=A0ACM8FV11 A0ACM8FV11 LOC8052388 PTHR12659:SF7 RHO-TYPE GTPASE ACTIVATING PROTEIN CROSSVEINLESS C, ISOFORM C molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 organelle organization#GO:0006996;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;actin cytoskeleton organization#GO:0030036;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;actin filament-based process#GO:0030029 G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8041207|UniProtKB=A0ACM8DNJ1 A0ACM8DNJ1 LOC8041207 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043372|UniProtKB=A0ACM8F0F9 A0ACM8F0F9 LOC8043372 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120849216|UniProtKB=A0ACM8F896 A0ACM8F896 LOC120849216 PTHR24377:SF1039 IP01015P-RELATED SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120841511|UniProtKB=A0ACM8ERW2 A0ACM8ERW2 LOC120841511 PTHR21420:SF10 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 1 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121835361|UniProtKB=A0ACM8FU89 A0ACM8FU89 LOC121836032 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031698|UniProtKB=A0ACM8DIL9 A0ACM8DIL9 LOC8031698 PTHR23408:SF3 METHYLMALONYL-COA MUTASE METHYLMALONIC ACIDURIA TYPE A PROTEIN, MITOCHONDRIAL hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 mutase#PC00160 IXOSC|EnsemblGenome=LOC121834288|UniProtKB=A0ACM8FPS2 A0ACM8FPS2 PTHR22984:SF33 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of mitotic cell cycle#GO:0007346;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8024840|UniProtKB=A0ACM8G4T2 A0ACM8G4T2 Grip91 PTHR19302:SF14 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 3 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;cell cycle process#GO:0022402;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC115327393|UniProtKB=A0ACM8EN56 A0ACM8EN56 LOC115327393 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8028840|UniProtKB=A0ACM8DYR2 A0ACM8DYR2 LOC8028840 PTHR10907:SF47 REGUCALCIN REGUCALCIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of calcium-mediated signaling#GO:0050848;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 esterase#PC00097;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034273|UniProtKB=A0ACM8DT58 A0ACM8DT58 LOC8034273 PTHR46600:SF1 THAP DOMAIN-CONTAINING THAP-TYPE DOMAIN-CONTAINING PROTEIN gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120836167|UniProtKB=A0ACM8FEB5 A0ACM8FEB5 LOC120836167 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8037729|UniProtKB=A0ACM8DMG0 A0ACM8DMG0 LOC8037729 PTHR21456:SF1 FAMILY WITH SEQUENCE SIMILARITY 102 C2 NT-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037623|UniProtKB=A0ACM8EJ16 A0ACM8EJ16 LOC8037623 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115331115|UniProtKB=A0ACM8ECM8 A0ACM8ECM8 LOC115331115 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115309046|UniProtKB=A0ACM8DND0 A0ACM8DND0 PTHR48069:SF3 DIHYDROFOLATE REDUCTASE DIHYDROFOLATE REDUCTASE oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948 IXOSC|EnsemblGenome=LOC120848313|UniProtKB=A0ACM8FR28 A0ACM8FR28 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC115327907|UniProtKB=A0ACM8E820 A0ACM8E820 LOC115327907 PTHR23428:SF386 HISTONE H2B HISTONE H2B 1-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8036181|UniProtKB=A0ACM8DJX6 A0ACM8DJX6 LOC8036181 PTHR46487:SF1 DNA REPAIR PROTEIN XRCC3 DNA REPAIR PROTEIN XRCC3 DNA binding#GO:0003677;four-way junction DNA binding#GO:0000400;binding#GO:0005488;nucleic acid binding#GO:0003676 DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;cellular component assembly#GO:0022607;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;mitotic recombination#GO:0006312;telomere organization#GO:0032200;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;replication fork#GO:0005657;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8040836|UniProtKB=A0ACM8EFT8 A0ACM8EFT8 LOC8040836 PTHR13723:SF200 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF B, ISOFORM B metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular structure organization#GO:0043062;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8039419|UniProtKB=A0ACM8DKC9 A0ACM8DKC9 Slimp PTHR11778:SF2 SERYL-TRNA SYNTHETASE SERINE--TRNA SYNTHETASE-LIKE PROTEIN SLIMP catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC115316940|UniProtKB=A0ACM8DX66 A0ACM8DX66 LOC115316940 PTHR12452:SF0 42-9-9 PROTEIN-RELATED THIOREDOXIN DOMAIN-CONTAINING PROTEIN 17 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;disulfide oxidoreductase activity#GO:0015036 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transporter#PC00227 IXOSC|EnsemblGenome=LOC121833242|UniProtKB=A0ACM8FIQ6 A0ACM8FIQ6 LOC121833242 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120838543|UniProtKB=A0ACM8EJH0 A0ACM8EJH0 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115314002|UniProtKB=A0ACM8DT99 A0ACM8DT99 LOC115314002 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121836180|UniProtKB=A0ACM8FX92 A0ACM8FX92 LOC121836180 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121047761|UniProtKB=A0ACM8FGI2 A0ACM8FGI2 LOC121047761 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023218|UniProtKB=A0ACM8EXX5 A0ACM8EXX5 LOC8023218 PTHR11849:SF317 ETS SUBFAMILY NOT NAMED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8029518|UniProtKB=A0ACM8ET85 A0ACM8ET85 LOC8029518 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975 glycosidase#PC00110;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115318971|UniProtKB=A0ACM8ES33 A0ACM8ES33 LOC115318971 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8044150|UniProtKB=A0ACM8E347 A0ACM8E347 LOC8044150 PTHR11075:SF54 PEPTIDE CHAIN RELEASE FACTOR LARGE RIBOSOMAL SUBUNIT PROTEIN ML62 catalytic activity, acting on RNA#GO:0140098;translation factor activity#GO:0180051;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689 translation release factor#PC00225 IXOSC|EnsemblGenome=LOC115325149|UniProtKB=A0ACM8EQV8 A0ACM8EQV8 LOC115325149 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC121838026|UniProtKB=A0ACM8G687 A0ACM8G687 LOC121838026 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312180|UniProtKB=A0ACM8F5G3 A0ACM8F5G3 LOC115312180 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8033201|UniProtKB=A0ACM8F733 A0ACM8F733 LOC8033201 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8029184|UniProtKB=A0ACM8DHS5 A0ACM8DHS5 LOC8029184 PTHR21231:SF3 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 2 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 G-protein#PC00020;protein-binding activity modulator#PC00095;small GTPase#PC00208 IXOSC|EnsemblGenome=LOC115326853|UniProtKB=A0ACM8EZV5 A0ACM8EZV5 LOC115326853 PTHR24388:SF108 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 770 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120847740|UniProtKB=A0ACM8G2C4 A0ACM8G2C4 LOC120847740 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8043501|UniProtKB=A0ACM8DT61 A0ACM8DT61 LOC8043501 PTHR11685:SF463 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING ANKYRIN REPEAT AND IBR DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8043594|UniProtKB=A0ACM8EA92 A0ACM8EA92 LOC8043594 PTHR11699:SF310 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE (NAD(+)) oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029 metabolic process#GO:0008152;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;catabolic process#GO:0009056;aldehyde catabolic process#GO:0046185 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC8042209|UniProtKB=A0ACM8DS89 A0ACM8DS89 LOC8042209 PTHR11085:SF19 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-6 transcription regulator activity#GO:0140110;acyltransferase activity#GO:0016746;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;transcription corepressor activity#GO:0003714;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription coregulator activity#GO:0003712;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;NAD-dependent protein lysine deacetylase activity#GO:0034979 negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121835424|UniProtKB=A0ACM8FTZ9 A0ACM8FTZ9 LOC121835424 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115327483|UniProtKB=A0ACM8E7Q5 A0ACM8E7Q5 LOC115327483 PTHR47978:SF30 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33A guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;metabolic process#GO:0008152;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular component assembly#GO:0022607;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endosome#GO:0005768;intracellular organelle#GO:0043229 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120840510|UniProtKB=A0ACM8EP95 A0ACM8EP95 LOC120840510 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121048445|UniProtKB=A0ACM8FJB8 A0ACM8FJB8 LOC121048445 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC120844667|UniProtKB=A0ACM8EZD3 A0ACM8EZD3 LOC120844667 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121836861|UniProtKB=A0ACM8G2B6 A0ACM8G2B6 LOC121836861 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332391|UniProtKB=A0ACM8F4L5 A0ACM8F4L5 LOC115332391 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8034081|UniProtKB=A0ACM8G1R0 A0ACM8G1R0 LOC8034081 PTHR46199:SF3 RAC GTPASE-ACTIVATING PROTEIN 1 RAC GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;mitotic spindle assembly#GO:0090307;mitotic sister chromatid segregation#GO:0000070;intracellular signal transduction#GO:0035556;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;organelle assembly#GO:0070925;mitotic cytokinesis#GO:0000281;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;cell division#GO:0051301;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;spindle elongation#GO:0051231;intracellular signaling cassette#GO:0141124;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;signal transduction#GO:0007165;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;Rho protein signal transduction#GO:0007266;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;nuclear division#GO:0000280;signaling#GO:0023052;mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;membrane-bounded organelle#GO:0043227;midbody#GO:0030496;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;cleavage furrow#GO:0032154;intracellular protein-containing complex#GO:0140535;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;nucleus#GO:0005634;protein-containing complex#GO:0032991;plasma membrane region#GO:0098590;cell division site#GO:0032153;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC8026396|UniProtKB=A0ACM8DS55 A0ACM8DS55 LOC8026396 PTHR10663:SF372 GUANYL-NUCLEOTIDE EXCHANGE FACTOR F-BOX ONLY PROTEIN 8 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC115329980|UniProtKB=A0ACM8EWR5 A0ACM8EWR5 LOC115329980 PTHR43272:SF118 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lipid droplet#GO:0005811;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944 ligase#PC00142 IXOSC|EnsemblGenome=LOC120840426|UniProtKB=A0ACM8ENK2 A0ACM8ENK2 LOC120840426 PTHR24393:SF175 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8023775|UniProtKB=A0ACM8DPI7 A0ACM8DPI7 eIF3f1 PTHR10540:SF6 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F translation factor activity#GO:0180051;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;translation initiation factor activity#GO:0003743;catalytic activity, acting on a protein#GO:0140096;translation initiation factor binding#GO:0031369;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC8035027|UniProtKB=A0ACM8DJP5 A0ACM8DJP5 PTHR12209:SF0 NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE EKC_KEOPS COMPLEX SUBUNIT TP53RK kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120838518|UniProtKB=A0ACM8EL00 A0ACM8EL00 LOC120838518 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8030224|UniProtKB=A0ACM8DT39 A0ACM8DT39 M6 PTHR11683:SF12 MYELIN PROTEOLIPID M6, ISOFORM F neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cellular component organization#GO:0016043;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cellular process#GO:0009987;neuron projection development#GO:0031175 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 myelin protein#PC00161 IXOSC|EnsemblGenome=LOC8032336|UniProtKB=A0ACM8EVY0 A0ACM8EVY0 LOC8032336 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115312887|UniProtKB=A0ACM8DSK4 A0ACM8DSK4 LOC115312887 PTHR38926:SF87 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6 protein-containing complex binding#GO:0044877;binding#GO:0005488 IXOSC|EnsemblGenome=LOC120839307|UniProtKB=A0ACM8ELV0 A0ACM8ELV0 LOC120839307 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8024520|UniProtKB=A0ACM8DT69 A0ACM8DT69 LOC8024520 PTHR37687:SF1 AGAP006772-PA SERINE_THREONINE-PROTEIN KINASE KINX ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8030719|UniProtKB=A0ACM8EGR3 A0ACM8EGR3 LOC8030719 PTHR11412:SF146 MACROGLOBULIN / COMPLEMENT LD23292P peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8040165|UniProtKB=A0ACM8DT09 A0ACM8DT09 LOC8040165 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8029359|UniProtKB=A0ACM8DS38 A0ACM8DS38 LOC8029359 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8052402|UniProtKB=A0ACM8DLM1 A0ACM8DLM1 PTHR31196:SF2 RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED RNA POLYMERASE II NUCLEAR LOCALIZATION PROTEIN SLC7A6OS-RELATED IXOSC|EnsemblGenome=LOC8042674|UniProtKB=A0ACM8DMT7 A0ACM8DMT7 LOC8042674 PTHR11079:SF156 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE-34 DEAMINASE REGULATORY SUBUNIT ADAT3 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;deaminase#PC00088;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120836684|UniProtKB=A0ACM8EFM4 A0ACM8EFM4 LOC120836684 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8033424|UniProtKB=A0ACM8DQP5 A0ACM8DQP5 LOC8033424 PTHR11360:SF260 MONOCARBOXYLATE TRANSPORTER IP12869P transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;monocarboxylic acid transport#GO:0015718;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8041345|UniProtKB=A0ACM8DWZ0 A0ACM8DWZ0 LOC8041345 PTHR10807:SF75 MYOTUBULARIN-RELATED LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG enzyme binding#GO:0019899;phosphatase binding#GO:0019902;binding#GO:0005488;protein binding#GO:0005515;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;protein phosphatase binding#GO:0019903;phosphatidylinositol-3,5-bisphosphate phosphatase activity#GO:0106018;phosphoric ester hydrolase activity#GO:0042578 lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856;lipid modification#GO:0030258;dephosphorylation#GO:0016311;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8038042|UniProtKB=A0ACM8FLF3 A0ACM8FLF3 LOC8038042 PTHR45874:SF4 HOMEOBOX PROTEIN ABDOMINAL-B HOMEOBOX PROTEIN ABDOMINAL-B double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC115320639|UniProtKB=A0ACM8E0F3 A0ACM8E0F3 PTHR18934:SF109 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8029950|UniProtKB=A0ACM8FEA3 A0ACM8FEA3 CenB1A PTHR23180:SF399 CENTAURIN/ARF BLOWN FUSE, ISOFORM A-RELATED enzyme activator activity#GO:0008047;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987 cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8041540|UniProtKB=A0ACM8DQF6 A0ACM8DQF6 LOC8041540 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;monocarboxylic acid biosynthetic process#GO:0072330 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115313557|UniProtKB=A0ACM8EU26 A0ACM8EU26 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120846604|UniProtKB=A0ACM8F3M2 A0ACM8F3M2 LOC120846604 PTHR24416:SF655 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115330981|UniProtKB=A0ACM8F8B3 A0ACM8F8B3 LOC115330981 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8038457|UniProtKB=A0ACM8F8C1 A0ACM8F8C1 LOC8038457 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115308671|UniProtKB=A0ACM8DMW0 A0ACM8DMW0 LOC115308671 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8024169|UniProtKB=A0ACM8DZC7 A0ACM8DZC7 Usp7 PTHR24006:SF644 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 7 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115324498|UniProtKB=A0ACM8F3V9 A0ACM8F3V9 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120841460|UniProtKB=A0ACM8FG49 A0ACM8FG49 LOC120841460 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120846073|UniProtKB=A0ACM8F2D6 A0ACM8F2D6 LOC120846073 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121836117|UniProtKB=A0ACM8FYL9 A0ACM8FYL9 LOC121836117 PTHR12606:SF141 SENTRIN/SUMO-SPECIFIC PROTEASE GH15225P-RELATED cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 protease#PC00190 IXOSC|EnsemblGenome=LOC8032233|UniProtKB=A0ACM8DMB4 A0ACM8DMB4 LOC8032233 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120836271|UniProtKB=A0ACM8F2N5 A0ACM8F2N5 LOC120836271 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115308617|UniProtKB=A0ACM8DMU2 A0ACM8DMU2 LOC115308617 PTHR46282:SF1 LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN LEUCINE-RICH MELANOCYTE DIFFERENTIATION-ASSOCIATED PROTEIN IXOSC|EnsemblGenome=LOC120842124|UniProtKB=A0ACM8ET36 A0ACM8ET36 LOC120842124 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative metabolic process#GO:1901135;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120843568|UniProtKB=A0ACM8EWH3 A0ACM8EWH3 LOC120843568 PTHR11616:SF328 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER metal ion transmembrane transporter activity#GO:0046873;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293 sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;glycine transport#GO:0015816;localization#GO:0051179;monoatomic cation transport#GO:0006812;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;carboxylic acid transport#GO:0046942;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120844150|UniProtKB=A0ACM8G2N4 A0ACM8G2N4 LOC120844150 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8035198|UniProtKB=A0ACM8E353 A0ACM8E353 LOC8035198 PTHR13399:SF2 TRANSLOCON-ASSOCIATED PROTEIN TRAP , GAMMA SUBUNIT TRANSLOCON-ASSOCIATED PROTEIN SUBUNIT GAMMA cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8037697|UniProtKB=A0ACM8F429 A0ACM8F429 Sbat PTHR10701:SF5 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N N-ALPHA-ACETYLTRANSFERASE 38, NATC AUXILIARY SUBUNIT RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8037056|UniProtKB=A0ACM8E2R1 A0ACM8E2R1 LOC8037056 PTHR24322:SF755 PKSB RETINOL DEHYDROGENASE 10 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8030832|UniProtKB=A0ACM8E0F2 A0ACM8E0F2 LOC8030832 PTHR42886:SF96 RE40534P-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE ABHD5 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620 glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid homeostasis#GO:0055088;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;homeostatic process#GO:0042592;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;organophosphate biosynthetic process#GO:0090407 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811 IXOSC|EnsemblGenome=LOC8037102|UniProtKB=A0ACM8DHW4 A0ACM8DHW4 Ced-12 PTHR12771:SF74 ENGULFMENT AND CELL MOTILITY CED-12 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8031513|UniProtKB=A0ACM8EDG4 A0ACM8EDG4 LOC8031513 PTHR15929:SF0 STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR STORE-OPERATED CALCIUM ENTRY-ASSOCIATED REGULATORY FACTOR regulation of calcium ion transport#GO:0051924;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of transport#GO:0051049;regulation of monoatomic ion transport#GO:0043269;regulation of metal ion transport#GO:0010959;regulation of biological process#GO:0050789 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115320865|UniProtKB=A0ACM8EJQ8 A0ACM8EJQ8 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052918|UniProtKB=A0ACM8E9C9 A0ACM8E9C9 LOC8052918 PTHR24356:SF450 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TRICORNERED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;establishment or maintenance of cell polarity#GO:0007163;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120845431|UniProtKB=A0ACM8F0M9 A0ACM8F0M9 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322418|UniProtKB=A0ACM8ER54 A0ACM8ER54 LOC115322418 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8029267|UniProtKB=A0ACM8DHW3 A0ACM8DHW3 LOC8029267 PTHR10196:SF57 SUGAR KINASE XYLULOSE KINASE carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 kinase#PC00137;carbohydrate kinase#PC00065 Ascorbate degradation#P02729>L-xylulose kinase#P02849 IXOSC|EnsemblGenome=LOC115312965|UniProtKB=A0ACM8DSJ0 A0ACM8DSJ0 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310456|UniProtKB=A0ACM8DPZ1 A0ACM8DPZ1 LOC115310456 PTHR11360:SF325 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC120845801|UniProtKB=A0ACM8F0V5 A0ACM8F0V5 Prp38 PTHR23142:SF1 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38A nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071 ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120849278|UniProtKB=A0ACM8F7I6 A0ACM8F7I6 LOC120849278 PTHR24652:SF70 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8026476|UniProtKB=A0ACM8DHT7 A0ACM8DHT7 LOC8026476 PTHR22654:SF2 G PROTEIN PATHWAY SUPPRESSOR 2 G PROTEIN PATHWAY SUPPRESSOR 2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 protein-containing complex#GO:0032991;transcription regulator complex#GO:0005667 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120849596|UniProtKB=A0ACM8F732 A0ACM8F732 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC115318916|UniProtKB=A0ACM8DYY5 A0ACM8DYY5 YME1L PTHR23076:SF144 METALLOPROTEASE M41 FTSH ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1 hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8038530|UniProtKB=A0ACM8F0J0 A0ACM8F0J0 LOC8038530 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8040166|UniProtKB=A0ACM8E0H5 A0ACM8E0H5 LOC8040166 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115328216|UniProtKB=A0ACM8FTZ6 A0ACM8FTZ6 LOC115328216 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC121046823|UniProtKB=A0ACM8FEZ2 A0ACM8FEZ2 Pdzd8 PTHR21519:SF1 PDZ DOMAIN-CONTAINING PROTEIN 8 PDZ DOMAIN-CONTAINING PROTEIN 8 intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 organelle membrane contact site#GO:0044232;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115330205|UniProtKB=A0ACM8EBX6 A0ACM8EBX6 LOC115330205 PTHR28498:SF1 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 7 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8027456|UniProtKB=A0ACM8F225 A0ACM8F225 LOC8027456 PTHR46467:SF1 TETHER CONTAINING UBX DOMAIN FOR GLUT4 TETHER CONTAINING UBX DOMAIN FOR GLUT4 carbohydrate homeostasis#GO:0033500;homeostatic process#GO:0042592;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;chemical homeostasis#GO:0048878;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;glucose homeostasis#GO:0042593 vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle#GO:0031982;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8026229|UniProtKB=A0ACM8F8V4 A0ACM8F8V4 LOC8026229 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 IXOSC|EnsemblGenome=LOC121837672|UniProtKB=A0ACM8G4J8 A0ACM8G4J8 LOC121837672 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837747|UniProtKB=A0ACM8G4Y7 A0ACM8G4Y7 LOC121837747 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8028370|UniProtKB=A0ACM8E968 A0ACM8E968 Sc2 PTHR10556:SF28 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE VERY-LONG-CHAIN ENOYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121047948|UniProtKB=A0ACM8G738 A0ACM8G738 LOC121047948 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115328459|UniProtKB=A0ACM8F9T9 A0ACM8F9T9 LOC115328459 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115323621|UniProtKB=A0ACM8ES21 A0ACM8ES21 LOC115323621 PTHR37412:SF2 C2 DOMAIN-CONTAINING PROTEIN 5 C2 DOMAIN-CONTAINING PROTEIN 5 phospholipid binding#GO:0005543;metal ion binding#GO:0046872;cation binding#GO:0043169;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 establishment of localization in cell#GO:0051649;positive regulation of transport#GO:0051050;establishment of protein localization#GO:0045184;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;protein localization to cell periphery#GO:1990778;regulation of localization#GO:0032879;regulation of transport#GO:0051049;positive regulation of vesicle fusion#GO:0031340;intracellular protein transmembrane transport#GO:0065002;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;protein localization to membrane#GO:0072657;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;regulation of protein localization#GO:0032880;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;positive regulation of organelle organization#GO:0010638;positive regulation of cellular process#GO:0048522;macromolecule localization#GO:0033036;biological regulation#GO:0065007;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;protein localization to plasma membrane#GO:0072659;regulation of transmembrane transport#GO:0034762;regulation of cellular process#GO:0050794;localization within membrane#GO:0051668;regulation of establishment of protein localization#GO:0070201;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC120837393|UniProtKB=A0ACM8EH89 A0ACM8EH89 LOC120837393 PTHR10858:SF23 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE II nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;programmed cell death#GO:0012501;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;catabolic process#GO:0009056;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC115309577|UniProtKB=A0ACM8FF66 A0ACM8FF66 LOC115309577 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121837944|UniProtKB=A0ACM8G767 A0ACM8G767 LOC121837944 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121838041|UniProtKB=A0ACM8G6C8 A0ACM8G6C8 LOC121838041 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120844050|UniProtKB=A0ACM8FLA3 A0ACM8FLA3 LOC120844050 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332753|UniProtKB=A0ACM8EEL2 A0ACM8EEL2 LOC115332753 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8026886|UniProtKB=A0ACM8E0I9 A0ACM8E0I9 PTHR11407:SF76 LYSOZYME C LYSOZYME lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC120839801|UniProtKB=A0ACM8EMT9 A0ACM8EMT9 LOC120839801 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120843920|UniProtKB=A0ACM8FNB7 A0ACM8FNB7 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052502|UniProtKB=A0ACM8DPA2 A0ACM8DPA2 Mrgn1 PTHR22996:SF30 MAHOGUNIN RE60872P-RELATED acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120837683|UniProtKB=A0ACM8EHI3 A0ACM8EHI3 Pits PTHR10816:SF19 MYELIN TRANSCRIPTION FACTOR 1-RELATED PROTEIN INTERACTING WITH TTK69 AND SIN3A, ISOFORM D transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8029668|UniProtKB=A0ACM8DWK0 A0ACM8DWK0 PTHR11177:SF144 CHITINASE CHITINASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8040035|UniProtKB=A0ACM8E250 A0ACM8E250 PTHR10977:SF3 DIPHOSPHOMEVALONATE DECARBOXYLASE DIPHOSPHOMEVALONATE DECARBOXYLASE lyase activity#GO:0016829;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 small molecule metabolic process#GO:0044281;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720;acetyl-CoA metabolic process#GO:0006084;isoprenoid biosynthetic process#GO:0008299;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 lyase#PC00144;decarboxylase#PC00089 Cholesterol biosynthesis#P00014>Diphosphomevalonate decarboxylase#P00496 IXOSC|EnsemblGenome=LOC121833799|UniProtKB=A0ACM8FN32 A0ACM8FN32 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030965|UniProtKB=A0ACM8G6B8 A0ACM8G6B8 LOC8030965 PTHR43563:SF26 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 serotonin metabolic process#GO:0042428;metabolic process#GO:0008152;amine catabolic process#GO:0009310;catabolic process#GO:0009056;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;phenol-containing compound metabolic process#GO:0018958 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidase#PC00175;oxidoreductase#PC00176 Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 IXOSC|EnsemblGenome=LOC120846546|UniProtKB=A0ACM8F2C7 A0ACM8F2C7 LOC120846546 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120842200|UniProtKB=A0ACM8EUB8 A0ACM8EUB8 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8042920|UniProtKB=A0ACM8F5U4 A0ACM8F5U4 LOC8042920 PTHR15260:SF1 SARCOSPAN SARCOSPAN cellular anatomical structure#GO:0110165;sarcolemma#GO:0042383;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC8032430|UniProtKB=A0ACM8DX63 A0ACM8DX63 PTHR24392:SF62 ZINC FINGER PROTEIN PROTEIN CHARLATAN-RELATED transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120848281|UniProtKB=A0ACM8F6F5 A0ACM8F6F5 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841894|UniProtKB=A0ACM8ESM5 A0ACM8ESM5 LOC120841894 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115330901|UniProtKB=A0ACM8FIN0 A0ACM8FIN0 LOC115330901 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115321600|UniProtKB=A0ACM8EVP9 A0ACM8EVP9 LOC115321600 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120848181|UniProtKB=A0ACM8F5L6 A0ACM8F5L6 LOC120848181 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027566|UniProtKB=A0ACM8F0J4 A0ACM8F0J4 LOC8027566 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8026397|UniProtKB=A0ACM8DRT3 A0ACM8DRT3 LOC8026397 PTHR18834:SF2 STEROID RECEPTOR RNA ACTIVATOR 1 STEROID RECEPTOR RNA ACTIVATOR 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115312648|UniProtKB=A0ACM8FRC4 A0ACM8FRC4 LOC115312648 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8028189|UniProtKB=A0ACM8G544 A0ACM8G544 Prp40 PTHR11864:SF0 PRE-MRNA-PROCESSING PROTEIN PRP40 PRE-MRNA-PROCESSING FACTOR 40 HOMOLOG A RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U2-type prespliceosome#GO:0071004;spliceosomal complex#GO:0005681 IXOSC|EnsemblGenome=LOC120841889|UniProtKB=A0ACM8ESR2 A0ACM8ESR2 LOC120841889 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8035460|UniProtKB=A0ACM8E1H4 A0ACM8E1H4 Gas41 PTHR47573:SF1 PROTEIN AF-9 HOMOLOG PROTEIN AF-9 HOMOLOG IXOSC|EnsemblGenome=LOC8027972|UniProtKB=A0ACM8EZC9 A0ACM8EZC9 LOC8027972 PTHR11977:SF143 VILLIN SUPERVILLIN, ISOFORM AE phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;actin filament binding#GO:0051015;actin binding#GO:0003779;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092 regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of actin filament depolymerization#GO:0030834;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;actin filament-based process#GO:0030029;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;negative regulation of actin filament depolymerization#GO:0030835 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC115328424|UniProtKB=A0ACM8E833 A0ACM8E833 LOC115328424 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115312661|UniProtKB=A0ACM8G284 A0ACM8G284 LOC115312661 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121047500|UniProtKB=A0ACM8FG84 A0ACM8FG84 LOC121047500 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330689|UniProtKB=A0ACM8EYR6 A0ACM8EYR6 LOC115330689 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8053629|UniProtKB=A0ACM8DXL0 A0ACM8DXL0 LOC8053629 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC115308927|UniProtKB=A0ACM8FJW0 A0ACM8FJW0 LOC115308927 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120838391|UniProtKB=A0ACM8EJP9 A0ACM8EJP9 LOC120838391 PTHR11923:SF51 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 FI02050P-RELATED cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8042021|UniProtKB=A0ACM8E814 A0ACM8E814 LOC8042021 PTHR16777:SF2 PROTEIN ECT2 PROTEIN ECT2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 cell cycle#GO:0007049;cell division#GO:0051301;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cytokinesis#GO:0000910;cytoskeleton-dependent cytokinesis#GO:0061640;mitotic cell cycle process#GO:1903047 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;cell periphery#GO:0071944;cell cortex#GO:0005938;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8026195|UniProtKB=A0ACM8DPQ9 A0ACM8DPQ9 LOC8026195 PTHR31684:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 COILED-COIL DOMAIN-CONTAINING PROTEIN 43 IXOSC|EnsemblGenome=LOC115324468|UniProtKB=A0ACM8E402 A0ACM8E402 LOC115324468 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8034585|UniProtKB=A0ACM8DJH3 A0ACM8DJH3 LOC8034585 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120838841|UniProtKB=A0ACM8EK19 A0ACM8EK19 LOC120838841 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034198|UniProtKB=A0ACM8DJ40 A0ACM8DJ40 LOC8034198 PTHR14540:SF2 INTEGRATOR COMPLEX SUBUNIT 15 INTEGRATOR COMPLEX SUBUNIT 15 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;integrator complex#GO:0032039;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8043288|UniProtKB=A0ACM8DTE6 A0ACM8DTE6 LOC8043288 PTHR24416:SF525 TYROSINE-PROTEIN KINASE RECEPTOR INSULIN-LIKE RECEPTOR transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane signaling receptor activity#GO:0004888 regulation of signaling#GO:0023051;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;positive regulation of signaling#GO:0023056;carbohydrate homeostasis#GO:0033500;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;cellular response to endogenous stimulus#GO:0071495;cell surface receptor signaling pathway#GO:0007166;chemical homeostasis#GO:0048878;regulation of MAPK cascade#GO:0043408;glucose homeostasis#GO:0042593;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;response to chemical#GO:0042221;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;response to nitrogen compound#GO:1901698;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cellular response to peptide hormone stimulus#GO:0071375;homeostatic process#GO:0042592;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;cellular response to insulin stimulus#GO:0032869;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;positive regulation of cellular process#GO:0048522;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cellular response to nitrogen compound#GO:1901699;positive regulation of response to stimulus#GO:0048584 protein kinase complex#GO:1902911;transferase complex#GO:1990234;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;transferase complex, transferring phosphorus-containing groups#GO:0061695;axon#GO:0030424;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797 transmembrane signal receptor#PC00197 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Insulin IGF#P00882;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895;PI3 kinase pathway#P00048>IR#P01187;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885 IXOSC|EnsemblGenome=LOC8052989|UniProtKB=A0ACM8DLL0 A0ACM8DLL0 LOC8052989 PTHR46321:SF1 KIF1-BINDING PROTEIN KIF-BINDING PROTEIN cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;neuron projection organization#GO:0106027;central nervous system development#GO:0007417;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 IXOSC|EnsemblGenome=LOC8054001|UniProtKB=A0ACM8F612 A0ACM8F612 LOC8054001 PTHR24258:SF148 SERINE PROTEASE-RELATED PROTEIN MASQUERADE protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8035590|UniProtKB=A0ACM8FBJ5 A0ACM8FBJ5 LOC8035590 PTHR24200:SF11 TOUCAN, ISOFORM A TOUCAN, ISOFORM A IXOSC|EnsemblGenome=LOC8026739|UniProtKB=A0ACM8DMT8 A0ACM8DMT8 LOC8026739 PTHR24201:SF18 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 kinase inhibitor#PC00139;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8039352|UniProtKB=A0ACM8DSX5 A0ACM8DSX5 LOC8039352 PTHR12755:SF3 CLEAVAGE/POLYADENYLATION FACTOR IA SUBUNIT CLP1P POLYNUCLEOTIDE 5'-HYDROXYL-KINASE NOL9 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120850311|UniProtKB=A0ACM8F8H3 A0ACM8F8H3 LOC120850311 PTHR45902:SF3 LATROPHILIN RECEPTOR-LIKE PROTEIN A METHUSELAH 15-LIKE PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8053136|UniProtKB=A0ACM8DSM4 A0ACM8DSM4 LOC8053136 PTHR15670:SF8 RHO GTPASE ACTIVATING PROTEIN 11A RHO-GAP DOMAIN-CONTAINING PROTEIN enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC115315197|UniProtKB=A0ACM8DV23 A0ACM8DV23 LOC115315197 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035078|UniProtKB=A0ACM8E897 A0ACM8E897 LOC8035078 PTHR21212:SF0 BERNARDINELLI-SEIP CONGENITAL LIPODYSTROPHY 2 HOMOLOG BSCL2 PROTEIN SEIPIN organelle organization#GO:0006996;lipid droplet organization#GO:0034389;cellular component organization#GO:0016043;lipid storage#GO:0019915;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8033838|UniProtKB=A0ACM8ELJ5 A0ACM8ELJ5 Elp2 PTHR44111:SF2 ELONGATOR COMPLEX PROTEIN 2 ELONGATOR COMPLEX PROTEIN 2 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;elongator holoenzyme complex#GO:0033588;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC8044045|UniProtKB=A0ACM8DL64 A0ACM8DL64 LOC8044045 PTHR24394:SF75 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8036190|UniProtKB=A0ACM8FAM0 A0ACM8FAM0 LOC8036190 PTHR13204:SF1 PTD012 PROTEIN BETA-KETO L-GULONATE DECARBOXYLASE ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;zinc ion binding#GO:0008270;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115325243|UniProtKB=A0ACM8FD27 A0ACM8FD27 LOC115325243 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115325000|UniProtKB=A0ACM8E5U4 A0ACM8E5U4 LOC115325000 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120848918|UniProtKB=A0ACM8G5G2 A0ACM8G5G2 LOC120848918 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051552|UniProtKB=A0ACM8G4M5 A0ACM8G4M5 LOC8051552 PTHR23302:SF40 TRANSMEMBRANE CHANNEL-RELATED TRANSMEMBRANE CHANNEL-LIKE PROTEIN passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 IXOSC|EnsemblGenome=LOC8034220|UniProtKB=A0ACM8E4E1 A0ACM8E4E1 LOC8034220 PTHR24347:SF412 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8033835|UniProtKB=A0ACM8DY49 A0ACM8DY49 LOC8033835 PTHR14344:SF3 WD REPEAT PROTEIN TRNA (34-2'-O)-METHYLTRANSFERASE REGULATOR WDR6 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;methylation#GO:0032259;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8026574|UniProtKB=A0ACM8FDB0 A0ACM8FDB0 Cdk5alpha PTHR23401:SF0 CYCLIN DEPENDANT KINASE-5 ACTIVATOR CYCLIN-DEPENDENT KINASE 5 ACTIVATOR kinase activator activity#GO:0019209;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase activator activity#GO:0030295;molecular function activator activity#GO:0140677;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase modulator#PC00140;kinase activator#PC00138 IXOSC|EnsemblGenome=LOC115322537|UniProtKB=A0ACM8E2V0 A0ACM8E2V0 LOC115322537 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120844551|UniProtKB=A0ACM8FYY9 A0ACM8FYY9 LOC120844551 PTHR11640:SF136 NEPHRIN NEPHRIN binding#GO:0005488;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8028420|UniProtKB=A0ACM8DGE8 A0ACM8DGE8 LOC8028420 PTHR12419:SF7 OTU DOMAIN CONTAINING PROTEIN UBIQUITINYL HYDROLASE 1 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115331901|UniProtKB=A0ACM8EMI1 A0ACM8EMI1 LOC115331901 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329257|UniProtKB=A0ACM8E9A5 A0ACM8E9A5 LOC115329257 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115318696|UniProtKB=A0ACM8G2N5 A0ACM8G2N5 LOC115318696 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC121836062|UniProtKB=A0ACM8FWE9 A0ACM8FWE9 LOC121836062 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023724|UniProtKB=A0ACM8FMS6 A0ACM8FMS6 PTHR24350:SF34 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;spindle microtubule#GO:0005876;microtubule#GO:0005874;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;spindle pole#GO:0000922;kinetochore#GO:0000776 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8028776|UniProtKB=A0ACM8E5L0 A0ACM8E5L0 LOC8028776 PTHR46589:SF1 APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS APOPTOTIC CHROMATIN CONDENSATION INDUCER IN THE NUCLEUS cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;exon-exon junction complex#GO:0035145;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8026790|UniProtKB=A0ACM8FIM5 A0ACM8FIM5 LOC8026790 PTHR45679:SF2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 3 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;response to unfolded protein#GO:0006986;endoplasmic reticulum unfolded protein response#GO:0030968;carbohydrate derivative metabolic process#GO:1901135;biological regulation#GO:0065007;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;cellular response to topologically incorrect protein#GO:0035967;protein metabolic process#GO:0019538;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8041224|UniProtKB=A0ACM8FH79 A0ACM8FH79 LOC8041224 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8032225|UniProtKB=A0ACM8E9L4 A0ACM8E9L4 LOC8032225 PTHR11829:SF380 FORKHEAD BOX PROTEIN PROTEIN FORK HEAD DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC120848538|UniProtKB=A0ACM8F678 A0ACM8F678 PTHR15440:SF0 XRP2 PROTEIN PROTEIN XRP2 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810 membrane-bounded organelle#GO:0043227;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane region#GO:0098590;cell periphery#GO:0071944;membrane#GO:0016020 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8039024|UniProtKB=A0ACM8FTN5 A0ACM8FTN5 Trpm PTHR13800:SF1 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL, SUBFAMILY M, MEMBER 6 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL TRPM channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC115327493|UniProtKB=A0ACM8E773 A0ACM8E773 LOC115327493 PTHR11851:SF226 METALLOPROTEASE CYTOCHROME B-C1 COMPLEX SUBUNIT 2, MITOCHONDRIAL intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036 organelle lumen#GO:0043233;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cytochrome complex#GO:0070069;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;respiratory chain complex#GO:0098803;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endopeptidase complex#GO:1905369;transporter complex#GO:1990351;respiratory chain complex III#GO:0045275 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8032324|UniProtKB=A0ACM8EEX5 A0ACM8EEX5 PIG-T PTHR12959:SF11 GPI TRANSAMIDASE COMPONENT PIG-T-RELATED GPI-ANCHOR TRANSAMIDASE COMPONENT PIGT biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;caspase complex#GO:0008303;peptidase complex#GO:1905368;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 IXOSC|EnsemblGenome=LOC8030833|UniProtKB=A0ACM8E0T6 A0ACM8E0T6 LOC8030833 PTHR22779:SF6 SD17342P SD17342P IXOSC|EnsemblGenome=LOC120850426|UniProtKB=A0ACM8FRA2 A0ACM8FRA2 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115328701|UniProtKB=A0ACM8E944 A0ACM8E944 LOC115328701 PTHR24381:SF486 ZINC FINGER PROTEIN ADULT ENHANCER FACTOR 1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121838149|UniProtKB=A0ACM8G897 A0ACM8G897 LOC121838149 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8050877|UniProtKB=A0ACM8E7H4 A0ACM8E7H4 LOC8050877 PTHR12848:SF22 REGULATORY-ASSOCIATED PROTEIN OF MTOR REGULATORY-ASSOCIATED PROTEIN OF MTOR protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular response to stress#GO:0033554;positive regulation of growth#GO:0045927;cellular response to chemical stimulus#GO:0070887;TORC1 signaling#GO:0038202;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;signaling#GO:0023052;cellular response to amino acid stimulus#GO:0071230;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;positive regulation of cell growth#GO:0030307;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to acid chemical#GO:0001101;response to stress#GO:0006950;TOR signaling#GO:0031929;regulation of cell growth#GO:0001558;response to chemical#GO:0042221;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of growth#GO:0040008;response to starvation#GO:0042594;regulation of cellular process#GO:0050794;cellular response to nutrient levels#GO:0031669;cellular response to starvation#GO:0009267;regulation of catabolic process#GO:0009894;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;biological regulation#GO:0065007 TOR complex#GO:0038201;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121836689|UniProtKB=A0ACM8FZQ4 A0ACM8FZQ4 LOC121836689 PTHR24559:SF465 TRANSPOSON TY3-I GAG-POL POLYPROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115330457|UniProtKB=A0ACM8EB14 A0ACM8EB14 LOC115330457 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115316430|UniProtKB=A0ACM8DVZ3 A0ACM8DVZ3 LOC115316430 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120838200|UniProtKB=A0ACM8EK25 A0ACM8EK25 LOC120838200 PTHR13087:SF0 NF-KAPPA B ACTIVATING PROTEIN NFKB ACTIVATING PROTEIN LIKE regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8032964|UniProtKB=A0ACM8EMB7 A0ACM8EMB7 LOC8032964 PTHR10075:SF92 BASIGIN RELATED PROTEIN TURTLE cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120840479|UniProtKB=A0ACM8EPN2 A0ACM8EPN2 PTHR11686:SF9 GAMMA GLUTAMYL TRANSPEPTIDASE GAMMA-GLUTAMYL TRANSPEPTIDASE, ISOFORM A catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8040715|UniProtKB=A0ACM8G341 A0ACM8G341 LOC8040715 PTHR24208:SF168 LIM/HOMEOBOX PROTEIN LHX PROTEIN APTEROUS DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8041617|UniProtKB=A0ACM8E547 A0ACM8E547 LOC8041617 PTHR11923:SF51 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 FI02050P-RELATED cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC121048321|UniProtKB=A0ACM8FGS5 A0ACM8FGS5 LOC121048321 PTHR47526:SF4 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8034591|UniProtKB=A0ACM8E2J3 A0ACM8E2J3 Srp54k PTHR11564:SF40 SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54 RNA binding#GO:0003723;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;binding#GO:0005488;nucleic acid binding#GO:0003676;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;signal sequence receptor activity#GO:0005048;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 establishment of protein localization to endoplasmic reticulum#GO:0072599;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;protein targeting to ER#GO:0045047;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein targeting to membrane#GO:0006612;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;transport#GO:0006810;protein targeting#GO:0006605;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;localization within membrane#GO:0051668 intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115330892|UniProtKB=A0ACM8ESD3 A0ACM8ESD3 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120844201|UniProtKB=A0ACM8EZ68 A0ACM8EZ68 LOC120844201 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8040946|UniProtKB=A0ACM8E584 A0ACM8E584 RpL37A PTHR48132:SF3 ZGC:171772 RIBOSOMAL PROTEIN L37A LIKE 2 IXOSC|EnsemblGenome=LOC121838414|UniProtKB=A0ACM8G843 A0ACM8G843 LOC121838414 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120836409|UniProtKB=A0ACM8EFX5 A0ACM8EFX5 LOC120836409 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120838158|UniProtKB=A0ACM8EJ97 A0ACM8EJ97 LOC120848663 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331275|UniProtKB=A0ACM8ECD3 A0ACM8ECD3 LOC115331275 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120850744|UniProtKB=A0ACM8FB04 A0ACM8FB04 LOC120850744 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052898|UniProtKB=A0ACM8ECJ6 A0ACM8ECJ6 LOC8052898 PTHR11588:SF513 TUBULIN TUBULIN ALPHA-4 CHAIN guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198 cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 IXOSC|EnsemblGenome=LOC8031447|UniProtKB=A0ACM8E5P8 A0ACM8E5P8 LOC8031447 PTHR24206:SF95 OS06G0237300 PROTEIN CYTOSKELETON-ASSOCIATED LIM DOMAIN PROTEIN-RELATED actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;actin cytoskeleton organization#GO:0030036;actin filament bundle assembly#GO:0051017;actin filament bundle organization#GO:0061572;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043 membrane#GO:0016020;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115324441|UniProtKB=A0ACM8E4P8 A0ACM8E4P8 LOC115324441 PTHR31094:SF2 RIKEN CDNA 2310061I04 GENE RIKEN CDNA 2310061I04 GENE IXOSC|EnsemblGenome=LOC8027122|UniProtKB=A0ACM8FLB9 A0ACM8FLB9 Grip PTHR46227:SF2 GLUTAMATE RECEPTOR-INTERACTING PROTEIN GRIP FI03335P cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;regulation of biological quality#GO:0065008;protein localization to cell junction#GO:1902414;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;endocytic recycling#GO:0032456;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;establishment of localization#GO:0051234;protein localization to synapse#GO:0035418;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;protein localization to cell periphery#GO:1990778;transport#GO:0006810;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;endosome to plasma membrane protein transport#GO:0099638;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 IXOSC|EnsemblGenome=LOC121835566|UniProtKB=A0ACM8FU80 A0ACM8FU80 LOC121835566 PTHR47968:SF50 CENTROMERE PROTEIN E KINESIN-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120837686|UniProtKB=A0ACM8EIR0 A0ACM8EIR0 LOC120837686 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115315002|UniProtKB=A0ACM8DUW1 A0ACM8DUW1 LOC115315002 PTHR32122:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT A General transcription by RNA polymerase I#P00022>TAF-IA#P00651;General transcription by RNA polymerase I#P00022>SL1 complex#P00653 IXOSC|EnsemblGenome=LOC115321400|UniProtKB=A0ACM8G3R6 A0ACM8G3R6 LOC115321400 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120848544|UniProtKB=A0ACM8F684 A0ACM8F684 PTHR14191:SF3 PDZ DOMAIN CONTAINING PROTEIN GH04176P-RELATED protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein localization to cell periphery#GO:1990778;localization within membrane#GO:0051668;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;cellular process#GO:0009987 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115327621|UniProtKB=A0ACM8E7W5 A0ACM8E7W5 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843121|UniProtKB=A0ACM8EVD3 A0ACM8EVD3 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052376|UniProtKB=A0ACM8E0X3 A0ACM8E0X3 LOC8052376 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;alpha-glucosidase activity#GO:0090599;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC8041958|UniProtKB=A0ACM8E419 A0ACM8E419 Rep PTHR11787:SF4 RAB GDP-DISSOCIATION INHIBITOR CHM, RAB ESCORT PROTEIN 1 protein targeting#GO:0006605;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;transport#GO:0006810;protein targeting to membrane#GO:0006612 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 G-protein modulator#PC00022;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8034991|UniProtKB=A0ACM8FU87 A0ACM8FU87 LOC8034991 PTHR47327:SF23 FI18240P1-RELATED FI17836P1 anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856 IXOSC|EnsemblGenome=LOC8053708|UniProtKB=A0ACM8E1R0 A0ACM8E1R0 LOC8053708 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8036764|UniProtKB=Q4PM64 Q4PM64 RpS21 PTHR10442:SF0 40S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN ES21 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;protein metabolic process#GO:0019538;translation#GO:0006412;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8025025|UniProtKB=A0ACM8EQ96 A0ACM8EQ96 LOC8025025 PTHR11177:SF144 CHITINASE CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;chitin metabolic process#GO:0006030;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8025638|UniProtKB=A0ACM8DXI2 A0ACM8DXI2 LOC8025638 PTHR14614:SF177 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120841069|UniProtKB=A0ACM8ER28 A0ACM8ER28 LOC120841069 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115309051|UniProtKB=A0ACM8FC52 A0ACM8FC52 LOC115309051 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG catalytic activity#GO:0003824;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of protein metabolic process#GO:0051246;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 IXOSC|EnsemblGenome=LOC8036734|UniProtKB=A0ACM8EJV7 A0ACM8EJV7 LOC8036734 PTHR46344:SF27 OS02G0202900 PROTEIN KELCH REPEAT SUPERFAMILY PROTEIN IXOSC|EnsemblGenome=LOC8033386|UniProtKB=A0ACM8FMF1 A0ACM8FMF1 LOC8033386 PTHR24246:SF57 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8043087|UniProtKB=A0ACM8FMD0 A0ACM8FMD0 LOC8043087 PTHR48025:SF28 OS02G0815200 PROTEIN RRM DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120843427|UniProtKB=A0ACM8FG15 A0ACM8FG15 LOC120843427 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8032834|UniProtKB=A0ACM8FBS8 A0ACM8FBS8 LOC8032834 PTHR11782:SF127 ADENOSINE/GUANOSINE DIPHOSPHATASE NUCLEOSIDE DIPHOSPHATE PHOSPHATASE hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 nucleoside diphosphate catabolic process#GO:0009134;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside diphosphate metabolic process#GO:0009132;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate catabolic process#GO:0046434 membrane#GO:0016020;cellular anatomical structure#GO:0110165 phosphatase#PC00181;nucleotide phosphatase#PC00173;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120844522|UniProtKB=A0ACM8G8F1 A0ACM8G8F1 LOC120844522 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115320946|UniProtKB=A0ACM8E0Q1 A0ACM8E0Q1 LOC115320946 PTHR10889:SF3 DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOXYRIBOSE-PHOSPHATE ALDOLASE lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside catabolic process#GO:0009164;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing small molecule catabolic process#GO:0034656;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;small molecule catabolic process#GO:0044282;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116 lyase#PC00144;aldolase#PC00044 IXOSC|EnsemblGenome=LOC8050812|UniProtKB=A0ACM8ECB9 A0ACM8ECB9 LOC8050812 PTHR44329:SF293 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Huntington disease#P00029>MLK-2#P00764 IXOSC|EnsemblGenome=LOC115309115|UniProtKB=A0ACM8F1L6 A0ACM8F1L6 LOC115309115 PTHR46599:SF9 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED 4-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8034347|UniProtKB=A0ACM8DMH8 A0ACM8DMH8 LOC8034347 PTHR12906:SF0 PROTEIN C20ORF24 RAB5-INTERACTING PROTEIN GEL COMPLEX SUBUNIT OPTI IXOSC|EnsemblGenome=LOC120847346|UniProtKB=A0ACM8F3T8 A0ACM8F3T8 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC121837071|UniProtKB=A0ACM8G200 A0ACM8G200 LOC121837071 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324715|UniProtKB=A0ACM8G035 A0ACM8G035 LOC115324715 PTHR24198:SF207 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 16 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121837399|UniProtKB=A0ACM8G3H8 A0ACM8G3H8 LOC121837399 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8035832|UniProtKB=A0ACM8E8Y5 A0ACM8E8Y5 RpLP2 PTHR21141:SF5 60S ACIDIC RIBOSOMAL PROTEIN FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN P2 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8028332|UniProtKB=A0ACM8FWZ6 A0ACM8FWZ6 LOC8028332 PTHR47969:SF15 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED microtubule motor activity#GO:0003777;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824 chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052 protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC115310702|UniProtKB=A0ACM8F0H2 A0ACM8F0H2 LOC115310702 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8027505|UniProtKB=A0ACM8E6M8 A0ACM8E6M8 LOC8027505 PTHR16461:SF5 TOLL-INTERACTING PROTEIN TOLL-INTERACTING PROTEIN protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130;enzyme binding#GO:0019899 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Toll receptor signaling pathway#P00054>Tollip#P01379 IXOSC|EnsemblGenome=LOC8032574|UniProtKB=A0ACM8DJK7 A0ACM8DJK7 LOC8032574 PTHR46584:SF1 HMG DOMAIN-CONTAINING PROTEIN 4 HMG DOMAIN-CONTAINING PROTEIN 4 HMG box transcription factor#PC00024 IXOSC|EnsemblGenome=LOC120844757|UniProtKB=A0ACM8F0L3 A0ACM8F0L3 LOC120844757 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835296|UniProtKB=A0ACM8FU66 A0ACM8FU66 LOC121835296 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 IXOSC|EnsemblGenome=LOC115315660|UniProtKB=A0ACM8G1N2 A0ACM8G1N2 YL-1 PTHR13275:SF4 YL-1 PROTEIN TRANSCRIPTION FACTOR-LIKE 1 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 72 HOMOLOG molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;ATPase complex#GO:1904949;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8050515|UniProtKB=A0ACM8F327 A0ACM8F327 LOC8050515 PTHR31518:SF3 ARGININE/SERINE-RICH PROTEIN PNISR ARGININE_SERINE-RICH PROTEIN PNISR IXOSC|EnsemblGenome=LOC121836176|UniProtKB=A0ACM8FZ10 A0ACM8FZ10 LOC121836176 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8053199|UniProtKB=A0ACM8FYE8 A0ACM8FYE8 LOC8053199 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804 sodium ion transport#GO:0006814;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8034269|UniProtKB=A0ACM8F3W5 A0ACM8F3W5 RIC-3 PTHR21723:SF6 RESISTANCE TO INHIBITORS OF CHOLINESTERASE PROTEIN 3 RIC3 RIC3 ACETYLCHOLINE RECEPTOR CHAPERONE, ISOFORM C regulation of biological process#GO:0050789;cellular process#GO:0009987;macromolecule localization#GO:0033036;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;synaptic transmission, cholinergic#GO:0007271;trans-synaptic signaling#GO:0099537;intracellular protein localization#GO:0008104;cell communication#GO:0007154;localization#GO:0051179 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 IXOSC|EnsemblGenome=LOC115322705|UniProtKB=A0ACM8EKZ9 A0ACM8EKZ9 LOC115322705 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8033685|UniProtKB=A0ACM8DR68 A0ACM8DR68 LOC8033685 PTHR14490:SF5 ZINC FINGER, ZZ TYPE PROTEIN KRI1 HOMOLOG ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;90S preribosome#GO:0030686;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8053759|UniProtKB=A0ACM8EDC7 A0ACM8EDC7 LOC8053759 PTHR24006:SF952 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 36 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;regulation of protein stability#GO:0031647;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC115309486|UniProtKB=A0ACM8FHJ8 A0ACM8FHJ8 LOC115309486 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8039125|UniProtKB=A0ACM8DKA8 A0ACM8DKA8 LOC8039125 PTHR13134:SF3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 13 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;TRAPP complex#GO:0030008;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8037137|UniProtKB=A0ACM8DRK6 A0ACM8DRK6 LOC8037137 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120841086|UniProtKB=A0ACM8EQI0 A0ACM8EQI0 LOC120841086 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326423|UniProtKB=A0ACM8ES75 A0ACM8ES75 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037382|UniProtKB=A0ACM8E380 A0ACM8E380 LOC8037382 PTHR10003:SF71 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN]-RELATED antioxidant activity#GO:0016209;catalytic activity#GO:0003824;copper ion binding#GO:0005507;oxidoreductase activity#GO:0016491;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;metal ion binding#GO:0046872 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to reactive oxygen species#GO:0000302;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to stress#GO:0006950;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121835044|UniProtKB=A0ACM8FS23 A0ACM8FS23 LOC121835044 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8031406|UniProtKB=A0ACM8FG78 A0ACM8FG78 LOC8031406 PTHR11037:SF20 TRANSCRIPTION FACTOR CP2 PROTEIN GRAINYHEAD DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8038496|UniProtKB=A0ACM8DK69 A0ACM8DK69 LOC8038496 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8044075|UniProtKB=A0ACM8DQC0 A0ACM8DQC0 Prp39 PTHR17204:SF5 PRE-MRNA PROCESSING PROTEIN PRP39-RELATED PRE-MRNA-PROCESSING FACTOR 39 RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;binding#GO:0005488;nucleic acid binding#GO:0003676 ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685 RNA metabolism protein#PC00031;RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8025584|UniProtKB=A0ACM8E1C4 A0ACM8E1C4 LOC8025584 PTHR23069:SF0 AAA DOMAIN-CONTAINING TAT-BINDING HOMOLOG 7 ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;histone binding#GO:0042393;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 transcription by RNA polymerase II#GO:0006366;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;nucleosome organization#GO:0034728;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;positive regulation of biosynthetic process#GO:0009891;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex disassembly#GO:0032984;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription initiation-coupled chromatin remodeling#GO:0045815;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;DNA-templated transcription initiation#GO:0006352 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8040934|UniProtKB=A0ACM8DVS4 A0ACM8DVS4 LOC8040934 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8051575|UniProtKB=A0ACM8F4H3 A0ACM8F4H3 LOC8051575 PTHR45999:SF4 UNC-13-4A, ISOFORM B UNC-13-4A, ISOFORM B IXOSC|EnsemblGenome=LOC120840304|UniProtKB=A0ACM8ENK9 A0ACM8ENK9 LOC120840304 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8028464|UniProtKB=A0ACM8E8E1 A0ACM8E8E1 LOC8028464 PTHR43829:SF33 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-9 channel activity#GO:0015267;carbohydrate transmembrane transporter activity#GO:0015144;passive transmembrane transporter activity#GO:0022803;water channel activity#GO:0015250;water transmembrane transporter activity#GO:0005372;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;water transport#GO:0006833;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;fluid transport#GO:0042044;organic hydroxy compound transport#GO:0015850;carbohydrate transport#GO:0008643;transport#GO:0006810;carbohydrate transmembrane transport#GO:0034219;cellular process#GO:0009987 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8041596|UniProtKB=A0ACM8EBB1 A0ACM8EBB1 LOC8041596 PTHR24320:SF294 RETINOL DEHYDROGENASE NADP-RETINOL DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817;small molecule metabolic process#GO:0044281 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121836543|UniProtKB=A0ACM8FZ50 A0ACM8FZ50 LOC121836543 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120851040|UniProtKB=A0ACM8FB16 A0ACM8FB16 LOC120851040 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848453|UniProtKB=A0ACM8FJ38 A0ACM8FJ38 LOC120848453 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8027684|UniProtKB=A0ACM8E918 A0ACM8E918 LOC8027684 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120844742|UniProtKB=A0ACM8EZ50 A0ACM8EZ50 LOC120844742 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8024566|UniProtKB=A0ACM8DXX6 A0ACM8DXX6 LOC8024566 PTHR43150:SF11 HYPERKINETIC, ISOFORM M HYPERKINETIC, ISOFORM M molecular function regulator activity#GO:0098772;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;binding#GO:0005488 regulation of transmembrane transport#GO:0034762;regulation of biological process#GO:0050789;regulation of monoatomic ion transmembrane transport#GO:0034765;regulation of metal ion transport#GO:0010959;regulation of monoatomic ion transport#GO:0043269;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of monoatomic cation transmembrane transport#GO:1904062;regulation of localization#GO:0032879;regulation of transport#GO:0051049 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 IXOSC|EnsemblGenome=LOC115312957|UniProtKB=A0ACM8EV14 A0ACM8EV14 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032682|UniProtKB=A0ACM8EWZ0 A0ACM8EWZ0 LOC8032682 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8041196|UniProtKB=A0ACM8DKN1 A0ACM8DKN1 Lamtor1 PTHR13401:SF2 RAGULATOR COMPLEX PROTEIN LAMTOR1 RAGULATOR COMPLEX PROTEIN LAMTOR1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584;response to acid chemical#GO:0001101;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;regulation of macromolecule metabolic process#GO:0060255;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;lysosomal membrane#GO:0005765;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;guanyl-nucleotide exchange factor complex#GO:0032045;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115311901|UniProtKB=A0ACM8DRC9 A0ACM8DRC9 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8039509|UniProtKB=A0ACM8DVE1 A0ACM8DVE1 LOC8039509 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8023456|UniProtKB=A0ACM8DH56 A0ACM8DH56 LOC8023456 PTHR12409:SF0 PREFOLDIN SUBUNIT 3 PREFOLDIN SUBUNIT 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;protein folding#GO:0006457;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8025917|UniProtKB=A0ACM8DRQ0 A0ACM8DRQ0 LOC8025917 PTHR43684:SF18 FAMILY NOT NAMED DODECENOYL-COA DELTA-ISOMERASE catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 IXOSC|EnsemblGenome=LOC8052464|UniProtKB=A0ACM8E804 A0ACM8E804 LOC8052464 PTHR16062:SF19 SWI/SNF-RELATED PROTEIN POLYBROMO-1 chromatin binding#GO:0003682;binding#GO:0005488 chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;RSC-type complex#GO:0016586;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;ATPase complex#GO:1904949 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120836110|UniProtKB=A0ACM8F8G8 A0ACM8F8G8 LOC120836110 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121046903|UniProtKB=A0ACM8FEZ5 A0ACM8FEZ5 LOC121046903 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8053015|UniProtKB=A0ACM8DR57 A0ACM8DR57 Rabex-5 PTHR23101:SF122 RAB GDP/GTP EXCHANGE FACTOR RAB5 GDP_GTP EXCHANGE FACTOR guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytosol#GO:0005829 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC120840506|UniProtKB=A0ACM8ENU9 A0ACM8ENU9 LOC120840506 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120836346|UniProtKB=A0ACM8FC57 A0ACM8FC57 LOC120836346 PTHR15201:SF1 CRSP70 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 26 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC8042310|UniProtKB=A0ACM8DWI6 A0ACM8DWI6 LOC8042310 PTHR43563:SF26 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 amine catabolic process#GO:0009310;metabolic process#GO:0008152;serotonin metabolic process#GO:0042428;phenol-containing compound metabolic process#GO:0018958;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 oxidoreductase#PC00176;oxidase#PC00175 Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 IXOSC|EnsemblGenome=LOC8030328|UniProtKB=A0ACM8EFK5 A0ACM8EFK5 Tcs1 PTHR17490:SF16 SUA5 THREONYLCARBAMOYL-AMP SYNTHASE RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological quality#GO:0065008;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;biological regulation#GO:0065007;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8027014|UniProtKB=A0ACM8DR45 A0ACM8DR45 LOC8027014 PTHR48083:SF6 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE 6 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC115331878|UniProtKB=A0ACM8G2Z4 A0ACM8G2Z4 LOC115331878 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844309|UniProtKB=A0ACM8EYE8 A0ACM8EYE8 LOC120844309 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115325283|UniProtKB=A0ACM8F0A5 A0ACM8F0A5 LOC115325283 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115309976|UniProtKB=A0ACM8DP59 A0ACM8DP59 LOC115309976 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115332497|UniProtKB=A0ACM8FJ98 A0ACM8FJ98 LOC115332497 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115330715|UniProtKB=A0ACM8F5F6 A0ACM8F5F6 LOC115330715 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038579|UniProtKB=A0ACM8ET12 A0ACM8ET12 timeout PTHR22940:SF4 TIMEOUT/TIMELESS-2 PROTEIN TIMELESS HOMOLOG DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular response to stress#GO:0033554;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;negative regulation of cell cycle#GO:0045786;DNA replication checkpoint signaling#GO:0000076;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;DNA integrity checkpoint signaling#GO:0031570;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;negative regulation of DNA-templated DNA replication#GO:2000104;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;replication fork#GO:0005657 IXOSC|EnsemblGenome=LOC8037533|UniProtKB=A0ACM8DI65 A0ACM8DI65 LOC8037533 PTHR45902:SF7 LATROPHILIN RECEPTOR-LIKE PROTEIN A G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8036846|UniProtKB=A0ACM8DK11 A0ACM8DK11 PTHR46262:SF2 FORKHEAD BOX PROTEIN BINIOU FORKHEAD BOX PROTEIN BINIOU transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8043958|UniProtKB=A0ACM8EL84 A0ACM8EL84 LOC8043958 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120845997|UniProtKB=A0ACM8F248 A0ACM8F248 LOC120845997 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836819|UniProtKB=A0ACM8EFH5 A0ACM8EFH5 LOC120836819 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839606|UniProtKB=A0ACM8ELL7 A0ACM8ELL7 LOC120839606 PTHR46688:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 16 IXOSC|EnsemblGenome=LOC8029884|UniProtKB=A0ACM8EA75 A0ACM8EA75 LOC8029884 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8035258|UniProtKB=A0ACM8F342 A0ACM8F342 LOC8035258 PTHR11616:SF279 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT SEROTONIN TRANSPORTER transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;metal ion transmembrane transporter activity#GO:0046873;heterocyclic compound binding#GO:1901363;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;binding#GO:0005488;serotonin binding#GO:0051378;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;chloride transmembrane transporter activity#GO:0015108;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;ion binding#GO:0043167;small molecule binding#GO:0036094;cation binding#GO:0043169;solute:sodium symporter activity#GO:0015370 transport#GO:0006810;amino acid transport#GO:0006865;establishment of localization#GO:0051234;import into cell#GO:0098657;establishment of localization in cell#GO:0051649;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;neurotransmitter transport#GO:0006836;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;organic hydroxy compound transport#GO:0015850;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;sodium ion transport#GO:0006814;metal ion transport#GO:0030001 cell junction#GO:0030054;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8052003|UniProtKB=A0ACM8DZP3 A0ACM8DZP3 LOC8052003 PTHR23349:SF112 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST 48 RELATED 1, ISOFORM B DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8023351|UniProtKB=A0ACM8DNF2 A0ACM8DNF2 LOC8023351 PTHR46474:SF1 TWO PORE CALCIUM CHANNEL PROTEIN 1 TWO PORE CHANNEL PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;lysosomal membrane#GO:0005765;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323 ion channel#PC00133 CCKR signaling map#P06959>TPC1/2#P07209 IXOSC|EnsemblGenome=LOC8042530|UniProtKB=A0ACM8EUK8 A0ACM8EUK8 LOC8042530 PTHR45620:SF44 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTOR, ORPHAN-RELATED G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8033899|UniProtKB=A0ACM8E661 A0ACM8E661 LOC8033899 PTHR48097:SF9 L-THREONINE ALDOLASE-RELATED L-THREONINE ALDOLASE aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 lyase#PC00144;aldolase#PC00044 IXOSC|EnsemblGenome=LOC121834419|UniProtKB=A0ACM8FQV8 A0ACM8FQV8 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849588|UniProtKB=A0ACM8G5R3 A0ACM8G5R3 LOC120849588 PTHR23349:SF50 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST PROTEIN TWIST transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC115318196|UniProtKB=A0ACM8FB71 A0ACM8FB71 LOC115318196 PTHR10907:SF47 REGUCALCIN REGUCALCIN catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of calcium-mediated signaling#GO:0050848;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;esterase#PC00097 IXOSC|EnsemblGenome=LOC115323173|UniProtKB=A0ACM8E3E8 A0ACM8E3E8 LOC115323173 PTHR47160:SF11 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036487|UniProtKB=A0ACM8EZB8 A0ACM8EZB8 LOC8036487 PTHR13767:SF2 TRNA-PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE TRUB1 catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;isomerase activity#GO:0016853 RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA modification#GO:0016556;pseudouridine synthesis#GO:0001522;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;isomerase#PC00135 IXOSC|EnsemblGenome=LOC8029284|UniProtKB=A0ACM8EZ61 A0ACM8EZ61 LOC8029284 PTHR11988:SF58 THYROTROPH EMBRYONIC FACTOR RELATED GH27708P binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120847789|UniProtKB=A0ACM8F3U1 A0ACM8F3U1 LOC120847789 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027971|UniProtKB=A0ACM8DJH1 A0ACM8DJH1 LOC8027971 PTHR33562:SF18 ATILLA, ISOFORM B-RELATED-RELATED RE19849P-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8024634|UniProtKB=A0ACM8EY86 A0ACM8EY86 LOC8024634 PTHR12258:SF5 JANUS-A/JANUS-B SEX-REGULATED PROTEIN JANUS-A-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC120849449|UniProtKB=A0ACM8G4I5 A0ACM8G4I5 LOC120849449 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8023341|UniProtKB=A0ACM8FN41 A0ACM8FN41 PTHR10830:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8028493|UniProtKB=A0ACM8E0E0 A0ACM8E0E0 LOC8028493 PTHR24365:SF556 TOLL-LIKE RECEPTOR PROTEIN TOLL-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;immune system process#GO:0002376;response to external biotic stimulus#GO:0043207;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;response to other organism#GO:0051707;biological regulation#GO:0065007;defense response to other organism#GO:0098542;cellular process#GO:0009987;defense response to symbiont#GO:0140546;signal transduction#GO:0007165;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Toll pathway-drosophila#P06217>TL#P06337;Toll receptor signaling pathway#P00054>TLR#P01346 IXOSC|EnsemblGenome=LOC8042754|UniProtKB=A0ACM8F605 A0ACM8F605 LOC8042754 PTHR11616:SF328 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;L-amino acid transmembrane transporter activity#GO:0015179;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081 nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;glycine transport#GO:0015816;monoatomic cation transport#GO:0006812;localization#GO:0051179;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121835754|UniProtKB=A0ACM8FVQ6 A0ACM8FVQ6 LOC121835754 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845208|UniProtKB=A0ACM8F033 A0ACM8F033 LOC120845208 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836896|UniProtKB=A0ACM8EGP8 A0ACM8EGP8 LOC120836896 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121835161|UniProtKB=A0ACM8FT61 A0ACM8FT61 LOC121835161 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848855|UniProtKB=A0ACM8FVV5 A0ACM8FVV5 LOC120848855 PTHR11219:SF72 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-M protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;cell junction organization#GO:0034330;system development#GO:0048731;anatomical structure development#GO:0048856;synapse organization#GO:0050808;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular process#GO:0009987;neuron projection development#GO:0031175;cell-cell adhesion#GO:0098609;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;synaptic membrane adhesion#GO:0099560;axonogenesis#GO:0007409;neuron development#GO:0048666;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;glutamatergic synapse#GO:0098978;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054 IXOSC|EnsemblGenome=LOC8041590|UniProtKB=A0ACM8E2F5 A0ACM8E2F5 LOC8041590 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE 5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC8040459|UniProtKB=A0ACM8EFK8 A0ACM8EFK8 LOC8040459 PTHR21027:SF1 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN54 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC8044140|UniProtKB=A0ACM8EAK8 A0ACM8EAK8 ema PTHR21481:SF0 PROTEIN CLEC16A PROTEIN CLEC16A vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;regulation of catabolic process#GO:0009894;regulation of macroautophagy#GO:0016241;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;regulation of autophagosome maturation#GO:1901096;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of autophagy#GO:0010506;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular localization#GO:0051641;localization#GO:0051179 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endosome#GO:0005768;intracellular organelle#GO:0043229;late endosome#GO:0005770;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 IXOSC|EnsemblGenome=LOC115316567|UniProtKB=A0ACM8EMM9 A0ACM8EMM9 LOC115316567 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC121836740|UniProtKB=A0ACM8G0A6 A0ACM8G0A6 LOC121836740 PTHR10253:SF12 POLYCOMB PROTEIN POLYCOMB PROTEIN EED nucleosome binding#GO:0031491;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;chromatin binding#GO:0003682;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8050912|UniProtKB=A0ACM8DLR1 A0ACM8DLR1 LOC8050912 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115330838|UniProtKB=A0ACM8EBV8 A0ACM8EBV8 LOC115330838 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318191|UniProtKB=A0ACM8DYB0 A0ACM8DYB0 LOC115318191 PTHR20648:SF0 ELONGIN-C ELONGIN-C protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC121836777|UniProtKB=A0ACM8G013 A0ACM8G013 LOC121836777 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310187|UniProtKB=A0ACM8DPM4 A0ACM8DPM4 PTHR11937:SF31 ACTIN ACTIN-RELATED PROTEIN 3 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;structural molecule activity#GO:0005198;cytoskeletal protein binding#GO:0008092 organelle organization#GO:0006996;cellular component organization#GO:0016043;Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;actin nucleation#GO:0045010;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;cortical actin cytoskeleton organization#GO:0030866;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin and actin related protein#PC00039 Huntington disease#P00029>Actin#P00807 IXOSC|EnsemblGenome=LOC115320062|UniProtKB=A0ACM8EYH6 A0ACM8EYH6 LOC115320062 PTHR23226:SF442 ZINC FINGER AND SCAN DOMAIN-CONTAINING PROTEIN GLASS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8050645|UniProtKB=A0ACM8DPT3 A0ACM8DPT3 LOC8050645 PTHR45727:SF11 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 small molecule binding#GO:0036094;binding#GO:0005488;sterol binding#GO:0032934;alcohol binding#GO:0043178;cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496 organic hydroxy compound transport#GO:0015850;system process#GO:0003008;establishment of localization#GO:0051234;sterol transport#GO:0015918;cholesterol homeostasis#GO:0042632;localization#GO:0051179;chemical homeostasis#GO:0048878;transport#GO:0006810;lipid localization#GO:0010876;homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;digestion#GO:0007586;lipid transport#GO:0006869;lipid homeostasis#GO:0055088;macromolecule localization#GO:0033036 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8030548|UniProtKB=A0ACM8EX30 A0ACM8EX30 LOC8030548 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8054052|UniProtKB=A0ACM8DLL2 A0ACM8DLL2 Cdc6 PTHR10763:SF26 CELL DIVISION CONTROL PROTEIN 6-RELATED DNA REPLICATION FACTOR CDC6 DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 replication origin binding protein#PC00199 IXOSC|EnsemblGenome=LOC115330706|UniProtKB=A0ACM8FKT2 A0ACM8FKT2 LOC115330706 PTHR15036:SF88 PIKACHURIN-LIKE PROTEIN PIKACHURIN signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856 cell periphery#GO:0071944;basement membrane#GO:0005604;membrane#GO:0016020;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell junction#GO:0030054 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8023763|UniProtKB=A0ACM8EJB5 A0ACM8EJB5 Caf1-55 PTHR22850:SF221 WD40 REPEAT FAMILY CHROMATIN ASSEMBLY FACTOR 1 P55 SUBUNIT binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;PcG protein complex#GO:0031519;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667 IXOSC|EnsemblGenome=LOC8041669|UniProtKB=A0ACM8DMV8 A0ACM8DMV8 LOC8041669 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034870|UniProtKB=A0ACM8FWN7 A0ACM8FWN7 LOC8034870 PTHR23050:SF552 CALCIUM BINDING PROTEIN AT16150P-RELATED ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;enzyme regulator activity#GO:0030234;cation binding#GO:0043169;molecular function regulator activity#GO:0098772 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;T cell activation#P00053>Calmodulin#P01305;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 IXOSC|EnsemblGenome=LOC120837895|UniProtKB=A0ACM8EJI7 A0ACM8EJI7 LOC120837895 PTHR11596:SF96 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115316092|UniProtKB=A0ACM8DVH5 A0ACM8DVH5 PTHR23334:SF69 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN GAMMA transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC121836407|UniProtKB=A0ACM8FZJ3 A0ACM8FZJ3 LOC121836407 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328813|UniProtKB=A0ACM8EIB9 A0ACM8EIB9 LOC115328813 PTHR24381:SF393 ZINC FINGER PROTEIN LD39664P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8029575|UniProtKB=A0ACM8FW05 A0ACM8FW05 LOC8029575 PTHR11793:SF13 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR PROTEIN DAUGHTERLESS transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8029157|UniProtKB=A0ACM8DHQ1 A0ACM8DHQ1 LOC8029157 PTHR23430:SF50 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8040488|UniProtKB=A0ACM8DQV3 A0ACM8DQV3 LOC8040488 PTHR14131:SF5 ANOSMIN ANOSMIN-1 nervous system development#GO:0007399;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;cellular process#GO:0009987;system development#GO:0048731;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;developmental process#GO:0032502;generation of neurons#GO:0048699;neuron differentiation#GO:0030182;animal gross anatomical part developmental process#GO:0160108 cell surface#GO:0009986;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC121838433|UniProtKB=A0ACM8G809 A0ACM8G809 LOC121838433 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC8034516|UniProtKB=A0ACM8F981 A0ACM8F981 LOC8034516 PTHR24356:SF450 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TRICORNERED catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;establishment or maintenance of cell polarity#GO:0007163 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8025090|UniProtKB=A0ACM8G168 A0ACM8G168 LOC8025090 PTHR15416:SF3 CAMP-DEPENDENT PROTEIN KINASE INHIBITOR/PKI NET DOMAIN-CONTAINING PROTEIN molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase inhibitor#PC00139;kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC120836468|UniProtKB=A0ACM8EES0 A0ACM8EES0 LOC120836468 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8028568|UniProtKB=A0ACM8EAY1 A0ACM8EAY1 LOC8028568 PTHR23349:SF108 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8050434|UniProtKB=A0ACM8DY47 A0ACM8DY47 LOC8050434 PTHR10183:SF437 CALPAIN CALPAIN-5 catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 IXOSC|EnsemblGenome=LOC8050475|UniProtKB=A0ACM8E3J0 A0ACM8E3J0 LOC8050475 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8038870|UniProtKB=A0ACM8FU26 A0ACM8FU26 LOC8038870 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8030430|UniProtKB=A0ACM8DH40 A0ACM8DH40 LOC8030430 PTHR13464:SF0 TRANSCRIPTIONAL REGULATOR PROTEIN HCNGP SAP30-BINDING PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8027163|UniProtKB=A0ACM8DIQ6 A0ACM8DIQ6 PTHR13798:SF12 RNA BINDING MOTIF RBM PROTEIN -RELATED RNA BINDING MOTIF PROTEIN 11-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115312012|UniProtKB=A0ACM8DRG1 A0ACM8DRG1 LOC115312012 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120845180|UniProtKB=A0ACM8FZ90 A0ACM8FZ90 LOC120845180 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321405|UniProtKB=A0ACM8EPX3 A0ACM8EPX3 LOC115321405 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320023|UniProtKB=A0ACM8E0G1 A0ACM8E0G1 PTHR46593:SF2 TRANSMEMBRANE PROTEIN 64 LD47277P homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;regulation of cytosolic calcium ion concentration#GO:0051480;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120845614|UniProtKB=A0ACM8F1N9 A0ACM8F1N9 LOC120845614 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094 biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115331434|UniProtKB=A0ACM8ECA5 A0ACM8ECA5 LOC115331434 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8028601|UniProtKB=A0ACM8E0P0 A0ACM8E0P0 LOC8028601 PTHR46571:SF1 SORTING NEXIN-8 SORTING NEXIN-8 cytosolic transport#GO:0016482;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 early endosome membrane#GO:0031901;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121832967|UniProtKB=A0ACM8FP57 A0ACM8FP57 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115319868|UniProtKB=A0ACM8DZI4 A0ACM8DZI4 LOC115319868 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835828|UniProtKB=A0ACM8FVY1 A0ACM8FVY1 LOC121835828 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8034512|UniProtKB=A0ACM8G444 A0ACM8G444 LOC8034512 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115315959|UniProtKB=A0ACM8ETW7 A0ACM8ETW7 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8033282|UniProtKB=A0ACM8E850 A0ACM8E850 LOC8033282 PTHR13136:SF11 TESTIS DEVELOPMENT PROTEIN PRTD TESTIS-EXPRESSED PROTEIN 30 IXOSC|EnsemblGenome=LOC8023836|UniProtKB=A0ACM8DWG7 A0ACM8DWG7 LOC8023836 PTHR11360:SF325 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8028121|UniProtKB=A0ACM8DQB4 A0ACM8DQB4 LOC8028121 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8054050|UniProtKB=A0ACM8DZU3 A0ACM8DZU3 LOC8054050 PTHR12174:SF23 SIGNAL PEPTIDE PEPTIDASE SIGNAL PEPTIDE PEPTIDASE aspartic-type endopeptidase activity#GO:0004190;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;cytoplasmic side of membrane#GO:0098562;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic side of endoplasmic reticulum membrane#GO:0098554;endomembrane system#GO:0012505 aspartic protease#PC00053;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120839682|UniProtKB=A0ACM8ENE3 A0ACM8ENE3 LOC120839682 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115310731|UniProtKB=A0ACM8FVS9 A0ACM8FVS9 LOC115310731 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8052872|UniProtKB=A0ACM8E892 A0ACM8E892 LOC8052872 PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8024202|UniProtKB=A0ACM8DI15 A0ACM8DI15 SerRS-m PTHR11778:SF23 SERYL-TRNA SYNTHETASE SERINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8040959|UniProtKB=A0ACM8E456 A0ACM8E456 LOC8040959 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;hydrolase activity#GO:0016787;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;A2-type glycerophospholipase activity#GO:0004623 IXOSC|EnsemblGenome=LOC8026925|UniProtKB=A0ACM8DIK5 A0ACM8DIK5 LOC8026925 PTHR28573:SF1 SPINDLE AND KINETOCHORE-ASSOCIATED PROTEIN 1 SKA COMPLEX SUBUNIT 1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 regulation of microtubule polymerization or depolymerization#GO:0031110;regulation of microtubule-based process#GO:0032886;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of microtubule cytoskeleton organization#GO:0070507;cell cycle#GO:0007049;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular process#GO:0009987;regulation of organelle organization#GO:0033043 microtubule#GO:0005874;spindle microtubule#GO:0005876;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitotic spindle#GO:0072686;chromosome#GO:0005694;kinetochore#GO:0000776;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779 IXOSC|EnsemblGenome=LOC8027559|UniProtKB=A0ACM8E7U1 A0ACM8E7U1 mino PTHR12563:SF23 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE BCDNA.GH07066 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;triglyceride biosynthetic process#GO:0019432;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115317219|UniProtKB=A0ACM8DXC3 A0ACM8DXC3 LOC115317219 PTHR24366:SF181 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS SLIT HOMOLOG 3 PROTEIN-LIKE immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115331337|UniProtKB=A0ACM8FU86 A0ACM8FU86 LOC115331337 PTHR11640:SF134 NEPHRIN ECHINOID, ISOFORM A-RELATED protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115309659|UniProtKB=A0ACM8DNX2 A0ACM8DNX2 LOC115309659 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846469|UniProtKB=A0ACM8FP24 A0ACM8FP24 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120849234|UniProtKB=A0ACM8FS92 A0ACM8FS92 LOC120849234 PTHR14024:SF49 PERILIPIN LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 1 regulation of localization#GO:0032879;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;lipid storage#GO:0019915;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120849422|UniProtKB=A0ACM8F6R6 A0ACM8F6R6 LOC120849422 PTHR46289:SF24 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE IXOSC|EnsemblGenome=LOC8027494|UniProtKB=A0ACM8DJ43 A0ACM8DJ43 LOC8027494 PTHR23003:SF51 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE-ARGININE PROTEIN 55 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC121838396|UniProtKB=A0ACM8G7T8 A0ACM8G7T8 LOC121838396 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121046826|UniProtKB=A0ACM8FFY8 A0ACM8FFY8 LOC121046826 PTHR44329:SF214 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED PROTEIN KINASE DOMAIN-CONTAINING PROTEIN protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8025118|UniProtKB=A0ACM8DUD8 A0ACM8DUD8 LOC8025118 PTHR12121:SF105 CARBON CATABOLITE REPRESSOR PROTEIN 4 PROTEIN ANGEL phosphoric ester hydrolase activity#GO:0042578;mRNA 3'-UTR binding#GO:0003730;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;nuclease activity#GO:0004518;mRNA binding#GO:0003729;exonuclease activity#GO:0004527;binding#GO:0005488;3'-5'-RNA exonuclease activity#GO:0000175;RNA nuclease activity#GO:0004540;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;mitochondrial RNA processing#GO:0000963;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA processing#GO:0006397;mRNA catabolic process#GO:0006402;mitochondrial RNA 3'-end processing#GO:0000965;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC120848089|UniProtKB=A0ACM8F648 A0ACM8F648 LOC120848089 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8032830|UniProtKB=A0ACM8EGC0 A0ACM8EGC0 CtBP PTHR46029:SF7 C-TERMINAL-BINDING PROTEIN C-TERMINAL-BINDING PROTEIN transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;protein binding#GO:0005515;transcription factor binding#GO:0008134;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 Wnt signaling pathway#P00057>C-terminal Binding Protein#P01439 IXOSC|EnsemblGenome=LOC8038842|UniProtKB=A0ACM8E4M0 A0ACM8E4M0 Kr-h2 PTHR12703:SF4 TRANSMEMBRANE PROTEIN 33 TRANSMEMBRANE PROTEIN 33 endoplasmic reticulum membrane organization#GO:0090158;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;cellular component organization#GO:0016043;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121833538|UniProtKB=A0ACM8FLL3 A0ACM8FLL3 LOC121833538 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN circulatory system development#GO:0072359;heart development#GO:0007507;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;post-embryonic development#GO:0009791;cell adhesion#GO:0007155;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 IXOSC|EnsemblGenome=LOC8051193|UniProtKB=A0ACM8DPD7 A0ACM8DPD7 LOC8051193 PTHR11570:SF0 S-ADENOSYLMETHIONINE DECARBOXYLASE S-ADENOSYLMETHIONINE DECARBOXYLASE PROENZYME lyase#PC00144;metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 IXOSC|EnsemblGenome=LOC8053730|UniProtKB=A0ACM8DLS0 A0ACM8DLS0 PTHR12771:SF2 ENGULFMENT AND CELL MOTILITY ELMO DOMAIN-CONTAINING PROTEIN 3 cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;Golgi apparatus#GO:0005794 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121836577|UniProtKB=A0ACM8FZ96 A0ACM8FZ96 LOC121836577 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC115330277|UniProtKB=A0ACM8EC11 A0ACM8EC11 LOC115330277 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121833048|UniProtKB=A0ACM8FHZ4 A0ACM8FHZ4 LOC121833048 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839325|UniProtKB=A0ACM8EMB3 A0ACM8EMB3 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842089|UniProtKB=A0ACM8ET13 A0ACM8ET13 LOC120842089 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843526|UniProtKB=A0ACM8EXE3 A0ACM8EXE3 LOC120843526 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC120846383|UniProtKB=A0ACM8FH39 A0ACM8FH39 LOC120846383 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8032050|UniProtKB=A0ACM8G378 A0ACM8G378 LOC8032050 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC121833174|UniProtKB=A0ACM8FJU5 A0ACM8FJU5 LOC121833174 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120845957|UniProtKB=A0ACM8F121 A0ACM8F121 LOC120845957 PTHR21964:SF13 BREAST CANCER METASTASIS-SUPPRESSOR 1 BRMS1 TRANSCRIPTIONAL REPRESSOR histone deacetylase binding#GO:0042826;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8053387|UniProtKB=A0ACM8DLS9 A0ACM8DLS9 rb PTHR11134:SF34 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP-3 COMPLEX SUBUNIT BETA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;lytic vacuole organization#GO:0080171;transport#GO:0006810;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;lysosome organization#GO:0007040;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;vacuole organization#GO:0007033;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane protein complex#GO:0098796 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121835438|UniProtKB=A0ACM8FTX9 A0ACM8FTX9 LOC121835438 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036162|UniProtKB=A0ACM8EB88 A0ACM8EB88 Gpb5 PTHR11515:SF13 GLYCOPROTEIN HORMONE BETA CHAIN GLYCOPROTEIN HORMONE BETA 5, ISOFORM A molecular function regulator activity#GO:0098772;hormone activity#GO:0005179;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peptide hormone#PC00179 IXOSC|EnsemblGenome=LOC115309274|UniProtKB=A0ACM8DNL5 A0ACM8DNL5 LOC115309274 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171 transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8052636|UniProtKB=A0ACM8E2I4 A0ACM8E2I4 LOC8052636 PTHR31539:SF1 CENTROSOMAL PROTEIN OF 19K CEP19 CENTROSOMAL PROTEIN OF 19 KDA cellular component organization#GO:0016043;cilium assembly#GO:0060271;Golgi to plasma membrane transport#GO:0006893;cell projection organization#GO:0030030;localization within membrane#GO:0051668;organelle assembly#GO:0070925;trans-Golgi to periciliary membrane compartment transport#GO:0097712;cilium organization#GO:0044782;post-Golgi vesicle-mediated transport#GO:0006892;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;Golgi vesicle transport#GO:0048193;transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;vesicle-mediated transport to the plasma membrane#GO:0098876;microtubule anchoring#GO:0034453;establishment of localization#GO:0051234;microtubule anchoring at microtubule organizing center#GO:0072393;cellular component organization or biogenesis#GO:0071840 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spindle pole#GO:0000922;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cilium#GO:0005929;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;spindle#GO:0005819;microtubule organizing center#GO:0005815;centrosome#GO:0005813 IXOSC|EnsemblGenome=LOC121045552|UniProtKB=A0ACM8G6C3 A0ACM8G6C3 LOC121045552 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8032806|UniProtKB=A0ACM8FCK0 A0ACM8FCK0 PTHR22883:SF203 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;protein targeting#GO:0006605;protein targeting to membrane#GO:0006612;localization within membrane#GO:0051668;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121046687|UniProtKB=A0ACM8FEL1 A0ACM8FEL1 LOC121046687 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115309003|UniProtKB=A0ACM8F498 A0ACM8F498 LOC115309003 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051937|UniProtKB=A0ACM8DZM5 A0ACM8DZM5 LOC8051937 PTHR12547:SF190 CCCH ZINC FINGER/TIS11-RELATED PROTEIN TIS11 mRNA binding#GO:0003729;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;protein-RNA adaptor activity#GO:0140517;molecular adaptor activity#GO:0060090;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8050483|UniProtKB=A0ACM8FN93 A0ACM8FN93 PTHR45638:SF1 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED ION CHANNEL SUBUNIT B, ISOFORM A channel activity#GO:0015267;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;guanyl ribonucleotide binding#GO:0032561;monoatomic cation transmembrane transporter activity#GO:0008324;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;transporter activity#GO:0005215;ribonucleotide binding#GO:0032553 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8042186|UniProtKB=A0ACM8DKV7 A0ACM8DKV7 LOC8042186 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308998|UniProtKB=A0ACM8FLW1 A0ACM8FLW1 LOC115308998 PTHR20910:SF1 AGAP001623-PA RELATED TO SOD IXOSC|EnsemblGenome=LOC8052058|UniProtKB=A0ACM8EER9 A0ACM8EER9 LOC8052058 PTHR14689:SF0 PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 82 IXOSC|EnsemblGenome=LOC8041449|UniProtKB=A0ACM8E0C0 A0ACM8E0C0 LOC8041449 PTHR11040:SF203 ZINC/IRON TRANSPORTER FI18611P1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120844892|UniProtKB=A0ACM8F016 A0ACM8F016 LOC120844892 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028190|UniProtKB=A0ACM8G3C8 A0ACM8G3C8 LOC8028190 PTHR33663:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 177 COILED-COIL DOMAIN-CONTAINING PROTEIN 177-LIKE IXOSC|EnsemblGenome=LOC8026129|UniProtKB=A0ACM8E159 A0ACM8E159 Pka-R1 PTHR11635:SF152 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Cell cycle#P00013>Protein kinase subunit#P00482;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Hedgehog signaling pathway#P00025>PKA#P00682;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Endothelin signaling pathway#P00019>PKA#P00570;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035 IXOSC|EnsemblGenome=LOC120839819|UniProtKB=A0ACM8EN64 A0ACM8EN64 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316570|UniProtKB=A0ACM8FV94 A0ACM8FV94 LOC115316570 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 steroid hydroxylase activity#GO:0008395;binding#GO:0005488;tetrapyrrole binding#GO:0046906;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;lipid metabolic process#GO:0006629;response to chemical#GO:0042221;response to stimulus#GO:0050896;steroid metabolic process#GO:0008202;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121834872|UniProtKB=A0ACM8FQN9 A0ACM8FQN9 LOC121834872 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120838682|UniProtKB=A0ACM8EL26 A0ACM8EL26 LOC120838682 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8039892|UniProtKB=A0ACM8DV46 A0ACM8DV46 PTHR18914:SF9 ALPHA CATENIN CATENIN ALPHA beta-catenin binding#GO:0008013;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell motility#GO:0048870;cell migration#GO:0016477 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796 non-motor actin binding protein#PC00165 Alzheimer disease-presenilin pathway#P00004>alpha-catenin#P00133;Wnt signaling pathway#P00057>alpha-catenin#P01471 IXOSC|EnsemblGenome=LOC8037617|UniProtKB=A0ACM8EAI9 A0ACM8EAI9 LOC8037617 PTHR10615:SF217 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;acetyltransferase activity#GO:0016407;binding#GO:0005488;transcription regulator activity#GO:0140110;protein N-acetyltransferase activity#GO:0034212;transferase activity#GO:0016740;histone acetyltransferase activity#GO:0004402;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;N-acetyltransferase activity#GO:0008080;chromatin binding#GO:0003682;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC120841836|UniProtKB=A0ACM8ESK0 A0ACM8ESK0 LOC120841836 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120849996|UniProtKB=A0ACM8FJ01 A0ACM8FJ01 LOC120849996 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120838647|UniProtKB=A0ACM8G816 A0ACM8G816 LOC120838647 PTHR45689:SF5 I[[H]] CHANNEL, ISOFORM E I[[H]] CHANNEL, ISOFORM E transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8032395|UniProtKB=A0ACM8G862 A0ACM8G862 LOC8032395 PTHR45803:SF5 SOX100B SOX100B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 HMG box transcription factor#PC00024;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115324602|UniProtKB=A0ACM8E420 A0ACM8E420 LOC115324602 PTHR12485:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT B NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 7 energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial ATP synthesis coupled electron transport#GO:0042775 membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115313203|UniProtKB=A0ACM8EEZ7 A0ACM8EEZ7 LOC115313203 PTHR10151:SF131 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE CHOLINEPHOSPHODIESTERASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115329408|UniProtKB=A0ACM8EAF8 A0ACM8EAF8 LOC115329408 PTHR22811:SF50 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein transport#GO:0006886;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;cellular component organization#GO:0016043;Golgi organization#GO:0007030 endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC121836611|UniProtKB=A0ACM8FZC3 A0ACM8FZC3 LOC121836611 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8023703|UniProtKB=A0ACM8ECV0 A0ACM8ECV0 LOC8023703 PTHR10161:SF66 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 TARTRATE-RESISTANT ACID PHOSPHATASE TYPE 5 small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;cation binding#GO:0043169;catalytic activity#GO:0003824;ferrous iron binding#GO:0008198;acid phosphatase activity#GO:0003993;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;iron ion binding#GO:0005506;phosphoric ester hydrolase activity#GO:0042578 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121835231|UniProtKB=A0ACM8FSU5 A0ACM8FSU5 LOC121835231 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115320890|UniProtKB=A0ACM8FP84 A0ACM8FP84 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042566|UniProtKB=A0ACM8FWB3 A0ACM8FWB3 LOC8042566 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120841570|UniProtKB=A0ACM8ES11 A0ACM8ES11 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058;cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115319487|UniProtKB=A0ACM8DZV8 A0ACM8DZV8 LOC115319487 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115309421|UniProtKB=A0ACM8F3M8 A0ACM8F3M8 LOC115309421 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120844190|UniProtKB=A0ACM8EXR2 A0ACM8EXR2 LOC120844190 PTHR12463:SF1 OXYGENASE-RELATED 2-OXOGLUTARATE AND FE-DEPENDENT OXYGENASE FAMILY PROTEIN oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8033980|UniProtKB=A0ACM8DYK6 A0ACM8DYK6 LOC8033980 PTHR10183:SF379 CALPAIN CALPAIN-A-RELATED cysteine protease#PC00081;protease#PC00190 Huntington disease#P00029>Calpain#P00788 IXOSC|EnsemblGenome=LOC121046566|UniProtKB=A0ACM8FEG2 A0ACM8FEG2 LOC121046566 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120850659|UniProtKB=A0ACM8FAJ8 A0ACM8FAJ8 LOC120850659 PTHR21705:SF12 RAI16 PROTEIN-RELATED FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN C-TERMINAL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024180|UniProtKB=A0ACM8DMW2 A0ACM8DMW2 Rim PTHR12157:SF21 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN RAB3 INTERACTING MOLECULE, ISOFORM F structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 transport#GO:0006810;synaptic vesicle cycle#GO:0099504;establishment of localization#GO:0051234;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;signal release#GO:0023061;regulation of exocytosis#GO:0017157;secretion#GO:0046903;localization#GO:0051179;cell communication#GO:0007154;regulation of secretion#GO:0051046;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;exocytic process#GO:0140029;regulated exocytosis#GO:0045055;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;regulation of transport#GO:0051049;regulation of localization#GO:0032879;vesicle-mediated transport in synapse#GO:0099003;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;synaptic signaling#GO:0099536;cellular component biogenesis#GO:0044085;neurotransmitter transport#GO:0006836;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;regulation of signaling#GO:0023051;regulation of neurotransmitter transport#GO:0051588;regulation of secretion by cell#GO:1903530;secretion by cell#GO:0032940;cellular localization#GO:0051641;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;regulation of synaptic vesicle exocytosis#GO:2000300;export from cell#GO:0140352;signaling#GO:0023052;regulation of neurotransmitter secretion#GO:0046928 synaptic membrane#GO:0097060;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;presynaptic active zone#GO:0048786;cell cortex#GO:0005938;presynapse#GO:0098793;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;synapse#GO:0045202 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8040008|UniProtKB=A0ACM8FMQ3 A0ACM8FMQ3 LOC8040008 PTHR10337:SF6 SHC TRANSFORMING PROTEIN CENTROSOMAL PROTEIN OF 152 KDA protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization or biogenesis#GO:0071840;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;microtubule organizing center organization#GO:0031023;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle assembly#GO:0070925;centriole replication#GO:0007099;microtubule cytoskeleton organization#GO:0000226;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;cell cycle process#GO:0022402;centrosome cycle#GO:0007098 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120849507|UniProtKB=A0ACM8F8W8 A0ACM8F8W8 LOC120849507 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8034712|UniProtKB=A0ACM8ECJ0 A0ACM8ECJ0 LOC8034712 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115323047|UniProtKB=A0ACM8E2N7 A0ACM8E2N7 LOC115323047 PTHR13121:SF0 GPI TRANSAMIDASE COMPONENT PIG-U GPI-ANCHOR TRANSAMIDASE COMPONENT PIGU protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;caspase complex#GO:0008303;cytoplasm#GO:0005737;peptidase complex#GO:1905368 IXOSC|EnsemblGenome=LOC8023421|UniProtKB=A0ACM8DUL6 A0ACM8DUL6 TfIIS PTHR11477:SF53 TRANSCRIPTION FACTOR S-II ZINC FINGER DOMAIN-CONTAINING PROTEIN IP08861P-RELATED transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8043597|UniProtKB=A0ACM8DGS2 A0ACM8DGS2 LOC8043597 PTHR42738:SF7 HYDROXYMETHYLGLUTARYL-COA LYASE HYDROXYMETHYLGLUTARYL-COA LYASE lyase activity#GO:0016829;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 lyase#PC00144 IXOSC|EnsemblGenome=LOC120841289|UniProtKB=A0ACM8ER79 A0ACM8ER79 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8037995|UniProtKB=A0ACM8DPU3 A0ACM8DPU3 PTHR46550:SF7 F-BOX ONLY PROTEIN 3 F-BOX ONLY PROTEIN 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121833292|UniProtKB=A0ACM8FKA3 A0ACM8FKA3 LOC121833292 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8036349|UniProtKB=A0ACM8DU41 A0ACM8DU41 LOC8036349 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8043208|UniProtKB=A0ACM8DRG4 A0ACM8DRG4 LOC8043208 PTHR45744:SF46 TYROSINE AMINOTRANSFERASE TYROSINE AMINOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 transaminase#PC00216 Tyrosine biosynthesis#P02784>Aromatic amino acid aminotransferase#P03213 IXOSC|EnsemblGenome=LOC115316166|UniProtKB=A0ACM8EYL7 A0ACM8EYL7 LOC115316166 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8038527|UniProtKB=A0ACM8DZB2 A0ACM8DZB2 PTHR10170:SF11 HUNTINGTON DISEASE PROTEIN HUNTINGTIN, ISOFORM A regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;organelle localization#GO:0051640;system development#GO:0048731;localization#GO:0051179;anatomical structure development#GO:0048856;vesicle localization#GO:0051648;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cytoskeleton-dependent intracellular transport#GO:0030705;developmental process#GO:0032502;transport#GO:0006810;regulation of response to stimulus#GO:0048583;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;vesicle cytoskeletal trafficking#GO:0099518;neurogenesis#GO:0022008;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport along microtubule#GO:0010970;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;establishment of organelle localization#GO:0051656;microtubule-based transport#GO:0099111;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic vesicle transport#GO:0048489;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;nervous system development#GO:0007399;synaptic vesicle localization#GO:0097479;microtubule-based process#GO:0007017;multicellular organism development#GO:0007275 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115320446|UniProtKB=A0ACM8FWV4 A0ACM8FWV4 LOC121835770 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8030976|UniProtKB=A0ACM8E1J6 A0ACM8E1J6 l(1)G0289 PTHR13055:SF12 TUMOR ENDOTHELIAL MARKER 7 RELATED LETHAL (1) G0289, ISOFORM D IXOSC|EnsemblGenome=LOC115315124|UniProtKB=A0ACM8F7A4 A0ACM8F7A4 LOC115315124 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316839|UniProtKB=A0ACM8ERZ4 A0ACM8ERZ4 LOC115316839 PTHR47501:SF10 TRANSPOSASE-RELATED DUF659 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121832934|UniProtKB=A0ACM8FSC8 A0ACM8FSC8 LOC121832934 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115310329|UniProtKB=A0ACM8DPM5 A0ACM8DPM5 LOC115310329 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120846564|UniProtKB=A0ACM8F2N3 A0ACM8F2N3 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular localization#GO:0051641;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;transport#GO:0006810;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;membrane organization#GO:0061024;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;nucleus#GO:0005634 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC115317279|UniProtKB=A0ACM8DXN7 A0ACM8DXN7 LOC115317279 PTHR12400:SF111 INOSITOL POLYPHOSPHATE KINASE KINASE phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;phospholipid metabolic process#GO:0006644;small molecule metabolic process#GO:0044281;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137 IXOSC|EnsemblGenome=LOC121046737|UniProtKB=A0ACM8FEQ1 A0ACM8FEQ1 LOC121046737 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8050983|UniProtKB=A0ACM8E614 A0ACM8E614 Orp8 PTHR10972:SF220 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN lipid binding#GO:0008289;steroid binding#GO:0005496;cholesterol binding#GO:0015485;alcohol binding#GO:0043178;sterol binding#GO:0032934;binding#GO:0005488;small molecule binding#GO:0036094 membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115310953|UniProtKB=A0ACM8F9X6 A0ACM8F9X6 LOC115310953 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311412|UniProtKB=A0ACM8F4T2 A0ACM8F4T2 LOC115311412 PTHR21258:SF62 DOCKING PROTEIN RELATED DOWNSTREAM OF KINASE cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8043068|UniProtKB=A0ACM8G3D8 A0ACM8G3D8 LOC8043068 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8025907|UniProtKB=A0ACM8F4Y8 A0ACM8F4Y8 PTHR21538:SF24 ANILLIN/RHOTEKIN RTKN PH DOMAIN-CONTAINING PROTEIN actomyosin structure organization#GO:0031032;actin cytoskeleton organization#GO:0030036;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cell division#GO:0051301;cellular component organization#GO:0016043;cell cycle#GO:0007049;cytoskeleton-dependent cytokinesis#GO:0061640;septin ring organization#GO:0031106;cortical actin cytoskeleton organization#GO:0030866;actin filament-based process#GO:0030029;cytokinetic process#GO:0032506;cortical cytoskeleton organization#GO:0030865;cytokinesis#GO:0000910;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;actomyosin contractile ring assembly#GO:0000915;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;septin cytoskeleton organization#GO:0032185 cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;contractile ring#GO:0070938;cytoskeleton#GO:0005856;actomyosin contractile ring#GO:0005826;membraneless organelle#GO:0043228 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC120836980|UniProtKB=A0ACM8EHA0 A0ACM8EHA0 LOC120836980 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8038652|UniProtKB=A0ACM8DK79 A0ACM8DK79 LOC8038652 PTHR13947:SF37 GNAT FAMILY N-ACETYLTRANSFERASE LD18367P acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC121834528|UniProtKB=A0ACM8FQI8 A0ACM8FQI8 PTHR45734:SF10 TENSIN BLISTERY, ISOFORM A anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8028762|UniProtKB=A0ACM8DN33 A0ACM8DN33 LOC8028762 PTHR12157:SF24 REGULATING SYNAPTIC MEMBRANE EXOCYTOSIS PROTEIN FIFE, ISOFORM D structural constituent of synapse#GO:0098918;structural molecule activity#GO:0005198 cellular component assembly#GO:0022607;regulation of trans-synaptic signaling#GO:0099177;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;regulation of localization#GO:0032879;exocytosis#GO:0006887;regulation of transport#GO:0051049;protein-containing complex organization#GO:0043933;regulated exocytosis#GO:0045055;exocytic process#GO:0140029;regulation of neurotransmitter secretion#GO:0046928;signaling#GO:0023052;export from cell#GO:0140352;regulation of synaptic vesicle exocytosis#GO:2000300;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;regulation of vesicle-mediated transport#GO:0060627;cellular localization#GO:0051641;secretion by cell#GO:0032940;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;signal release from synapse#GO:0099643;chemical synaptic transmission#GO:0007268;regulation of secretion#GO:0051046;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;regulation of exocytosis#GO:0017157;signal release#GO:0023061;trans-synaptic signaling#GO:0099537 membrane#GO:0016020;cell periphery#GO:0071944;cell cortex#GO:0005938;presynapse#GO:0098793;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;presynaptic active zone#GO:0048786;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120842065|UniProtKB=A0ACM8ET01 A0ACM8ET01 LOC120842065 PTHR45840:SF2 RHOMBOID-RELATED PROTEIN PROTEIN RHOMBOID-RELATED IXOSC|EnsemblGenome=LOC8051016|UniProtKB=A0ACM8DVT4 A0ACM8DVT4 LOC8051016 PTHR33444:SF2 SI:DKEY-19B23.12-RELATED TRANSMEMBRANE PROTEIN 272-RELATED IXOSC|EnsemblGenome=LOC8038157|UniProtKB=A0ACM8DWG6 A0ACM8DWG6 LOC8038157 PTHR22957:SF333 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 25 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of autophagosome maturation#GO:1901096;regulation of macroautophagy#GO:0016241;regulation of catabolic process#GO:0009894;regulation of autophagy#GO:0010506;regulation of protein-containing complex disassembly#GO:0043244;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 autophagosome#GO:0005776;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC121047347|UniProtKB=A0ACM8G4N2 A0ACM8G4N2 LOC121047347 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC115324757|UniProtKB=A0ACM8FIR0 A0ACM8FIR0 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8036187|UniProtKB=A0ACM8DJU8 A0ACM8DJU8 LOC8036187 PTHR21738:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG RIBOSOMAL RNA PROCESSING PROTEIN 36 HOMOLOG ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120844397|UniProtKB=A0ACM8EY98 A0ACM8EY98 LOC120844397 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030021|UniProtKB=A0ACM8G1Z8 A0ACM8G1Z8 LOC8030021 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120850038|UniProtKB=A0ACM8F927 A0ACM8F927 LOC120850038 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC121833526|UniProtKB=A0ACM8FMH2 A0ACM8FMH2 LOC121833526 PTHR10075:SF83 BASIGIN RELATED CONTACTIN cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8035876|UniProtKB=A0ACM8E689 A0ACM8E689 LOC8035876 PTHR15288:SF0 DENN DOMAIN-CONTAINING PROTEIN 2 UDENN DOMAIN-CONTAINING PROTEIN enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8026187|UniProtKB=A0ACM8DHD5 A0ACM8DHD5 LOC8026187 PTHR13205:SF15 TRANSMEMBRANE PROTEIN 15-RELATED DOLICHOL KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 IXOSC|EnsemblGenome=LOC115326642|UniProtKB=A0ACM8FMC4 A0ACM8FMC4 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle process#GO:1903047 membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8052256|UniProtKB=A0ACM8EA77 A0ACM8EA77 LOC8052256 PTHR12420:SF50 PHD FINGER PROTEIN LD43541P-RELATED nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120842882|UniProtKB=A0ACM8EUP5 A0ACM8EUP5 LOC120842882 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115321245|UniProtKB=A0ACM8EXL5 A0ACM8EXL5 LOC115321245 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115328788|UniProtKB=A0ACM8F2C3 A0ACM8F2C3 LOC115328788 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121838225|UniProtKB=A0ACM8G8I7 A0ACM8G8I7 LOC121838225 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC121835893|UniProtKB=A0ACM8FXE1 A0ACM8FXE1 LOC121835893 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844745|UniProtKB=A0ACM8EZN4 A0ACM8EZN4 LOC120844745 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC121833908|UniProtKB=A0ACM8FN89 A0ACM8FN89 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8031115|UniProtKB=A0ACM8DVB5 A0ACM8DVB5 LOC8031115 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121838548|UniProtKB=A0ACM8G962 A0ACM8G962 LOC121838548 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8040526|UniProtKB=A0ACM8E9T9 A0ACM8E9T9 LOC8040526 PTHR23240:SF37 DNA CROSS-LINK REPAIR PROTEIN PSO2/SNM1-RELATED PROTEIN ARTEMIS catalytic activity, acting on DNA#GO:0140097;damaged DNA binding#GO:0003684;DNA exonuclease activity#GO:0004529;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;hydrolase activity#GO:0016787;DNA binding#GO:0003677;exonuclease activity#GO:0004527;binding#GO:0005488;nucleic acid binding#GO:0003676 interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;telomere organization#GO:0032200;cellular response to stress#GO:0033554 DNA repair complex#GO:1990391;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120839541|UniProtKB=A0ACM8EM84 A0ACM8EM84 LOC120839541 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8034052|UniProtKB=A0ACM8EU98 A0ACM8EU98 LOC8034052 PTHR24390:SF271 ZINC FINGER PROTEIN FI23536P1-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120838741|UniProtKB=A0ACM8G7H1 A0ACM8G7H1 LOC120838741 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8027273|UniProtKB=A0ACM8ECC8 A0ACM8ECC8 san PTHR42919:SF8 N-ALPHA-ACETYLTRANSFERASE N-ALPHA-ACETYLTRANSFERASE 50 protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;acyltransferase activity#GO:0016746;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080 chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;cellular process#GO:0009987;cell cycle process#GO:0022402;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;mitotic sister chromatid cohesion#GO:0007064 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 transferase#PC00220;acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC115324262|UniProtKB=A0ACM8EL58 A0ACM8EL58 LOC115324262 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8035066|UniProtKB=A0ACM8DJQ7 A0ACM8DJQ7 LOC8035066 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121832847|UniProtKB=A0ACM8G8G7 A0ACM8G8G7 LOC121832847 PTHR20844:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8040665|UniProtKB=A0ACM8E5Y9 A0ACM8E5Y9 LOC8040665 PTHR23291:SF50 BAX INHIBITOR-RELATED PROTEIN LIFEGUARD 4 calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873 biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC120837731|UniProtKB=A0ACM8EI36 A0ACM8EI36 LOC120837731 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115328642|UniProtKB=A0ACM8E9H6 A0ACM8E9H6 LOC115328642 PTHR11276:SF42 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE BETA catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;DNA-directed DNA polymerase activity#GO:0003887 response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 IXOSC|EnsemblGenome=ISCI023560|UniProtKB=Q4PMC9 Q4PMC9 PTHR12826:SF13 RIBONUCLEASE Y RNA-BINDING PROTEIN PNO1 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC8023924|UniProtKB=A0ACM8E1C6 A0ACM8E1C6 LOC8023924 PTHR45961:SF6 IP21249P IP21249P catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 Oxidative stress response#P00046>MKP5#P01131 IXOSC|EnsemblGenome=LOC115329091|UniProtKB=A0ACM8EAF9 A0ACM8EAF9 Scamp PTHR10687:SF96 SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN SCAMP SECRETORY CARRIER-ASSOCIATED MEMBRANE PROTEIN exocytosis#GO:0006887;secretion by cell#GO:0032940;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;trans-Golgi network membrane#GO:0032588;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;vesicle membrane#GO:0012506;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115330631|UniProtKB=A0ACM8F2L6 A0ACM8F2L6 LOC115330631 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115331309|UniProtKB=A0ACM8EBX7 A0ACM8EBX7 LOC115331309 PTHR46897:SF2 VESICLE-ASSOCIATED MEMBRANE PROTEIN 4 VESICLE-ASSOCIATED MEMBRANE PROTEIN 4 IXOSC|EnsemblGenome=LOC121833323|UniProtKB=A0ACM8FKF0 A0ACM8FKF0 LOC121833323 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115328171|UniProtKB=A0ACM8F7Q4 A0ACM8F7Q4 LOC115328171 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8041936|UniProtKB=A0ACM8G656 A0ACM8G656 LOC8041936 PTHR44981:SF2 PERICENTRIN-LIKE PROTEIN, ISOFORM F PERICENTRIN-LIKE PROTEIN, ISOFORM F protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 IXOSC|EnsemblGenome=LOC8043489|UniProtKB=A0ACM8DTR5 A0ACM8DTR5 LOC8043489 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253;cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025 IXOSC|EnsemblGenome=LOC120851133|UniProtKB=A0ACM8FBH8 A0ACM8FBH8 LOC120851133 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835611|UniProtKB=A0ACM8FVW5 A0ACM8FVW5 LOC121835611 PTHR46473:SF28 GH08155P ELRR (EXTRACELLULAR LEUCINE-RICH REPEAT) ONLY IXOSC|EnsemblGenome=LOC8053360|UniProtKB=A0ACM8DPU8 A0ACM8DPU8 LOC8053360 PTHR13600:SF33 LEUCINE CARBOXYL METHYLTRANSFERASE LEUCINE CARBOXYL METHYLTRANSFERASE 1 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171 regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of sister chromatid segregation#GO:0033045;regulation of cell communication#GO:0010646;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;regulation of response to stimulus#GO:0048583;regulation of chromosome segregation#GO:0051983;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of chromosome separation#GO:1905818;regulation of nuclear division#GO:0051783;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of mitotic cell cycle#GO:0007346 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8050884|UniProtKB=A0ACM8DTI0 A0ACM8DTI0 LOC8050884 PTHR10165:SF35 LIPID PHOSPHATE PHOSPHATASE RE23632P phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;dephosphorylation#GO:0016311;lipid modification#GO:0030258;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 membrane#GO:0016020;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8028718|UniProtKB=A0ACM8DH45 A0ACM8DH45 LOC8028718 PTHR11929:SF249 ALPHA- 1,3 -FUCOSYLTRANSFERASE FUCOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;transferase activity#GO:0016740;catalytic activity#GO:0003824;alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8033476|UniProtKB=A0ACM8E7D0 A0ACM8E7D0 LOC8033476 PTHR13196:SF14 DENN DOMAIN-CONTAINING UDENN DOMAIN-CONTAINING PROTEIN binding#GO:0005488;phospholipid binding#GO:0005543;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;import into cell#GO:0098657;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8033690|UniProtKB=A0ACM8DV36 A0ACM8DV36 LOC8033690 PTHR10799:SF973 SNF2/RAD54 HELICASE FAMILY BRAHMA CHROMATIN-REMODELING COMPLEX ATPASE SUBUNIT catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;chromatin organization#GO:0006325;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 IXOSC|EnsemblGenome=LOC8026203|UniProtKB=A0ACM8EKN7 A0ACM8EKN7 LOC8026203 PTHR10900:SF126 PERIOSTIN-RELATED MUCIN-5AC-RELATED cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;homophilic cell-cell adhesion#GO:0007156;cell adhesion#GO:0007155;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120840358|UniProtKB=A0ACM8ENR5 A0ACM8ENR5 LOC120840358 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8034666|UniProtKB=A0ACM8EL79 A0ACM8EL79 LOC8034666 PTHR12198:SF0 HOMEOBOX PROTEIN PROSPERO/PROX-1/CEH-26 HOMEOBOX PROTEIN PROSPERO sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8043744|UniProtKB=A0ACM8DXX4 A0ACM8DXX4 LOC8043744 PTHR13481:SF0 SREBP REGULATING GENE PROTEIN SREBP REGULATING GENE PROTEIN IXOSC|EnsemblGenome=LOC115316619|UniProtKB=A0ACM8FST7 A0ACM8FST7 LOC115316619 PTHR23345:SF15 VITELLOGENIN-RELATED VITELLOGENIN-6 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 storage protein#PC00210 IXOSC|EnsemblGenome=LOC115309135|UniProtKB=A0ACM8DNH3 A0ACM8DNH3 LOC115309135 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322735|UniProtKB=A0ACM8G4U7 A0ACM8G4U7 LOC115322735 PTHR24256:SF579 TRYPTASE-RELATED WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC121047257|UniProtKB=A0ACM8FFP7 A0ACM8FFP7 LOC121047257 PTHR22984:SF33 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE 1 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8024068|UniProtKB=A0ACM8EZG6 A0ACM8EZG6 LOC8024068 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120840834|UniProtKB=A0ACM8FSC7 A0ACM8FSC7 LOC120840834 PTHR45718:SF7 TRANSCRIPTIONAL ACTIVATOR CUBITUS INTERRUPTUS C2H2-TYPE DOMAIN-CONTAINING PROTEIN gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8029943|UniProtKB=A0ACM8DZN1 A0ACM8DZN1 Ost48 PTHR10830:SF0 DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE 48 KDA SUBUNIT glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;oligosaccharyltransferase complex#GO:0008250;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115327572|UniProtKB=A0ACM8EMS4 A0ACM8EMS4 LOC115327572 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330;synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell leading edge#GO:0031252;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253 IXOSC|EnsemblGenome=LOC115323362|UniProtKB=A0ACM8ELE3 A0ACM8ELE3 LOC115323362 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8041852|UniProtKB=A0ACM8F5R1 A0ACM8F5R1 LOC8041852 PTHR13105:SF24 MYELOID LEUKEMIA FACTOR MYELOID LEUKEMIA FACTOR regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8038711|UniProtKB=A0ACM8E633 A0ACM8E633 LOC8038711 PTHR46513:SF13 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121048246|UniProtKB=A0ACM8FT86 A0ACM8FT86 LOC121048246 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120841866|UniProtKB=A0ACM8ESL9 A0ACM8ESL9 LOC120841866 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid localization#GO:0010876;localization#GO:0051179;ceramide metabolic process#GO:0006672;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule localization#GO:0033036;lipid transport#GO:0006869;transport#GO:0006810;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;establishment of localization#GO:0051234 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8050915|UniProtKB=A0ACM8E2V3 A0ACM8E2V3 LOC8050915 PTHR11122:SF13 APOSPORY-ASSOCIATED PROTEIN C-RELATED GLUCOSE-6-PHOSPHATE 1-EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115328583|UniProtKB=A0ACM8ENY5 A0ACM8ENY5 LOC115328583 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121046995|UniProtKB=A0ACM8FE03 A0ACM8FE03 LOC121046995 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025144|UniProtKB=A0ACM8EK99 A0ACM8EK99 LOC8025144 PTHR23235:SF183 KRUEPPEL-LIKE TRANSCRIPTION FACTOR DENDRITIC ARBOR REDUCTION PROTEIN 1 transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121046268|UniProtKB=A0ACM8FDP9 A0ACM8FDP9 LOC121046268 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121834757|UniProtKB=A0ACM8FRX2 A0ACM8FRX2 LOC121834757 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033299|UniProtKB=A0ACM8E8J3 A0ACM8E8J3 LOC8033299 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8026106|UniProtKB=A0ACM8FJ91 A0ACM8FJ91 Usp39 PTHR21646:SF16 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 39 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;regulation of protein stability#GO:0031647;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115318457|UniProtKB=A0ACM8EWJ6 A0ACM8EWJ6 LOC115318457 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8041074|UniProtKB=A0ACM8EFS2 A0ACM8EFS2 PTHR15623:SF11 SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2-RELATED SPERMATOGENESIS-ASSOCIATED SERINE-RICH PROTEIN 2 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC115313832|UniProtKB=A0ACM8DT85 A0ACM8DT85 FBXO11 PTHR22990:SF20 F-BOX ONLY PROTEIN F-BOX ONLY PROTEIN 11 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8033339|UniProtKB=A0ACM8DZJ9 A0ACM8DZJ9 LOC8033339 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043614|UniProtKB=A0ACM8DVA8 A0ACM8DVA8 LOC8043614 PTHR23003:SF71 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN FI21236P1-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nuclear mRNA surveillance#GO:0071028;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;rRNA processing#GO:0006364;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC115323348|UniProtKB=A0ACM8EW17 A0ACM8EW17 LOC115323348 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8024138|UniProtKB=A0ACM8FED8 A0ACM8FED8 LOC8024138 PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC115310822|UniProtKB=A0ACM8DQ31 A0ACM8DQ31 LOC115310822 PTHR43028:SF4 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL MONOPHOSPHATASE 3-RELATED nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC120848632|UniProtKB=A0ACM8F5A4 A0ACM8F5A4 anchor PTHR22829:SF5 DEP DOMAIN PROTEIN LYSOSOMAL CHOLESTEROL SIGNALING PROTEIN negative regulation of cell communication#GO:0010648;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;negative regulation of BMP signaling pathway#GO:0030514;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;regulation of BMP signaling pathway#GO:0030510 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8031427|UniProtKB=A0ACM8DI90 A0ACM8DI90 LOC8031427 PTHR24412:SF272 KELCH PROTEIN BTB DOMAIN-CONTAINING PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8031984|UniProtKB=A0ACM8DJ03 A0ACM8DJ03 LOC8031984 PTHR31278:SF2 CHCHD1 SMALL RIBOSOMAL SUBUNIT PROTEIN MS37 IXOSC|EnsemblGenome=LOC8030472|UniProtKB=A0ACM8E6Q8 A0ACM8E6Q8 l(3)76BDm PTHR12975:SF6 TRANSPORT PROTEIN TRAPP TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 8 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;TRAPP complex#GO:0030008 IXOSC|EnsemblGenome=LOC121835305|UniProtKB=A0ACM8FSD1 A0ACM8FSD1 LOC121835305 PTHR46762:SF2 NUCLEOREDOXIN-LIKE PROTEIN 2 THIOREDOXIN DOMAIN-CONTAINING PROTEIN oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8029189|UniProtKB=A0ACM8DHR3 A0ACM8DHR3 LOC8029189 PTHR19924:SF26 UTP15 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 FAMILY MEMBER U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 15 HOMOLOG regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase I#GO:0006356;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of transcription by RNA polymerase I#GO:0045943;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121836675|UniProtKB=A0ACM8FZ33 A0ACM8FZ33 LOC121836675 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8036606|UniProtKB=A0ACM8EVS2 A0ACM8EVS2 LOC8036606 PTHR10366:SF404 NAD DEPENDENT EPIMERASE/DEHYDRATASE NAD-DEPENDENT EPIMERASE_DEHYDRATASE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 dehydratase#PC00091;lyase#PC00144;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052119|UniProtKB=A0ACM8DUB9 A0ACM8DUB9 LOC8052119 PTHR19316:SF18 PROTEIN FOLDING REGULATOR HSP70-BINDING PROTEIN 1 molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120845290|UniProtKB=A0ACM8F0I1 A0ACM8F0I1 LOC120845290 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120846755|UniProtKB=A0ACM8F366 A0ACM8F366 AP-1-2beta PTHR11134:SF33 ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER AP COMPLEX SUBUNIT BETA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 organelle membrane#GO:0031090;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;clathrin-coated vesicle#GO:0030136;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117;AP-1 adaptor complex#GO:0030121;trans-Golgi network transport vesicle#GO:0030140;intracellular membrane-bounded organelle#GO:0043231;vesicle#GO:0031982;membrane protein complex#GO:0098796;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;clathrin vesicle coat#GO:0030125;vesicle coat#GO:0030120;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;coated vesicle#GO:0030135;coated membrane#GO:0048475;intracellular organelle#GO:0043229;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;intracellular vesicle#GO:0097708 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120841467|UniProtKB=A0ACM8ERA2 A0ACM8ERA2 Dus4 PTHR11082:SF31 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(20A_20B) SYNTHASE [NAD(P)+]-LIKE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8032865|UniProtKB=A0ACM8E5B1 A0ACM8E5B1 LOC8032865 PTHR10766:SF177 TRANSMEMBRANE 9 SUPERFAMILY PROTEIN TRANSMEMBRANE 9 SUPERFAMILY MEMBER 1 cellular localization#GO:0051641;localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;cellular process#GO:0009987;localization within membrane#GO:0051668 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120846281|UniProtKB=A0ACM8F174 A0ACM8F174 LOC120846281 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040529|UniProtKB=A0ACM8EAP1 A0ACM8EAP1 Aldh-III PTHR43570:SF16 ALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;metabolic process#GO:0008152 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC115326785|UniProtKB=A0ACM8EI58 A0ACM8EI58 N PTHR24040:SF13 LAMININ G-LIKE DOMAIN-CONTAINING PROTEIN FIBROPELLIN-1 IXOSC|EnsemblGenome=LOC115311255|UniProtKB=A0ACM8F5K6 A0ACM8F5K6 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120843671|UniProtKB=A0ACM8EWQ0 A0ACM8EWQ0 LOC120843671 PTHR11530:SF11 D-AMINO ACID OXIDASE D-AMINO ACID OXIDASE 2, ISOFORM A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 IXOSC|EnsemblGenome=LOC115313435|UniProtKB=A0ACM8DST6 A0ACM8DST6 LOC115313435 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120843649|UniProtKB=A0ACM8EWC7 A0ACM8EWC7 LOC120843649 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121832859|UniProtKB=A0ACM8G8R8 A0ACM8G8R8 LOC121832859 PTHR24229:SF114 NEUROPEPTIDES RECEPTOR ALLATOSTATIN C RECEPTOR 1-RELATED binding#GO:0005488;neuropeptide binding#GO:0042923;peptide binding#GO:0042277;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;neuropeptide signaling pathway#GO:0007218 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 IXOSC|EnsemblGenome=LOC115316208|UniProtKB=A0ACM8DW55 A0ACM8DW55 LOC115316208 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC120841274|UniProtKB=A0ACM8ERC3 A0ACM8ERC3 LOC120841274 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311280|UniProtKB=A0ACM8EQQ1 A0ACM8EQQ1 LOC115311280 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833184|UniProtKB=A0ACM8FJV7 A0ACM8FJV7 LOC121833184 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC115321710|UniProtKB=A0ACM8E257 A0ACM8E257 LOC115321710 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313766|UniProtKB=A0ACM8EU20 A0ACM8EU20 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040134|UniProtKB=A0ACM8FQ32 A0ACM8FQ32 LOC8040134 PTHR11636:SF138 POU DOMAIN HOMEOBOX PROTEIN CEH-6 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC121046324|UniProtKB=A0ACM8FDT9 A0ACM8FDT9 LOC121046324 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835512|UniProtKB=A0ACM8FUB9 A0ACM8FUB9 LOC121835512 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030800|UniProtKB=A0ACM8EXJ6 A0ACM8EXJ6 LOC8030800 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8039460|UniProtKB=A0ACM8EGI6 A0ACM8EGI6 LOC8039460 PTHR42643:SF24 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR 20A-RELATED transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8041112|UniProtKB=A0ACM8DKK0 A0ACM8DKK0 LOC8041112 PTHR15180:SF1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 1 DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;rRNA transcription#GO:0009303;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transcription factor TFIIIC complex#GO:0000127 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8041684|UniProtKB=A0ACM8DKR9 A0ACM8DKR9 Ran PTHR24071:SF0 RAN GTPASE GTP-BINDING NUCLEAR PROTEIN RAN hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;gene expression#GO:0010467;protein export from nucleus#GO:0006611;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein import into nucleus#GO:0006606;protein transport#GO:0015031;ribosome biogenesis#GO:0042254;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;ribosomal subunit export from nucleus#GO:0000054;transport#GO:0006810;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;macromolecule biosynthetic process#GO:0009059;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;organelle localization#GO:0051640;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC121837538|UniProtKB=A0ACM8G3H9 A0ACM8G3H9 Mob3 PTHR22599:SF11 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB KINASE ACTIVATOR-LIKE 3 kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8035788|UniProtKB=A0ACM8EBA3 A0ACM8EBA3 numb PTHR47368:SF2 NUMB NUMB cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115324435|UniProtKB=A0ACM8EH68 A0ACM8EH68 sws PTHR14226:SF29 NEUROPATHY TARGET ESTERASE/SWISS CHEESE D.MELANOGASTER NEUROPATHY TARGET ESTERASE SWS phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121;esterase#PC00097 IXOSC|EnsemblGenome=LOC121838362|UniProtKB=A0ACM8G7S9 A0ACM8G7S9 LOC121838362 PTHR33426:SF52 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8052087|UniProtKB=A0ACM8DWD5 A0ACM8DWD5 LOC8052087 PTHR10819:SF3 PHOSPHOTRIESTERASE-RELATED N-ACETYLTAURINE HYDROLASE esterase#PC00097;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115311094|UniProtKB=A0ACM8DQF9 A0ACM8DQF9 LOC115311094 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840806|UniProtKB=A0ACM8EQG5 A0ACM8EQG5 LOC120840806 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030465|UniProtKB=A0ACM8DH50 A0ACM8DH50 SWIP PTHR31409:SF0 WASH COMPLEX SUBUNIT 4 WASH COMPLEX SUBUNIT 4 endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120843379|UniProtKB=A0ACM8EW13 A0ACM8EW13 LOC120843379 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120837479|UniProtKB=A0ACM8EHG5 A0ACM8EHG5 LOC120837479 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8054077|UniProtKB=A0ACM8FNI9 A0ACM8FNI9 sli PTHR45836:SF4 SLIT HOMOLOG PROTEIN SLIT multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 IXOSC|EnsemblGenome=LOC120836852|UniProtKB=A0ACM8G8N1 A0ACM8G8N1 LOC120836852 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115310787|UniProtKB=A0ACM8EXM4 A0ACM8EXM4 LOC115310787 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8026723|UniProtKB=A0ACM8DQW5 A0ACM8DQW5 LOC8026723 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115313352|UniProtKB=A0ACM8F191 A0ACM8F191 LOC115313352 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043670|UniProtKB=A0ACM8EKT8 A0ACM8EKT8 LIMK1 PTHR46485:SF4 LIM DOMAIN KINASE 1 LIM DOMAIN KINASE 1 kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121835035|UniProtKB=A0ACM8FT45 A0ACM8FT45 LOC121835035 PTHR13353:SF5 TRANSMEMBRANE PROTEIN 19 TRANSMEMBRANE PROTEIN 19 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8053476|UniProtKB=A0ACM8EES2 A0ACM8EES2 LOC8053476 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8028364|UniProtKB=A0ACM8G4C5 A0ACM8G4C5 LOC8028364 PTHR24042:SF5 NEL HOMOLOG PROTEIN KINASE C-BINDING PROTEIN NELL1-LIKE PROTEIN calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC115323390|UniProtKB=A0ACM8E2X7 A0ACM8E2X7 LOC115323390 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052133|UniProtKB=A0ACM8DM18 A0ACM8DM18 LOC8052133 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121047027|UniProtKB=A0ACM8G4B3 A0ACM8G4B3 LOC121047027 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837815|UniProtKB=A0ACM8G4X2 A0ACM8G4X2 LOC121837815 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120838226|UniProtKB=A0ACM8EIT7 A0ACM8EIT7 LOC120838226 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039611|UniProtKB=A0ACM8DKF4 A0ACM8DKF4 LOC8039611 PTHR21228:SF69 FAST LEU-RICH DOMAIN-CONTAINING GH07286P-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;cellular process#GO:0009987;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070 membrane-enclosed lumen#GO:0031974;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8033319|UniProtKB=A0ACM8DWS4 A0ACM8DWS4 PNPase PTHR11252:SF0 POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE POLYRIBONUCLEOTIDE NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408 gene expression#GO:0010467;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;mitochondrial RNA processing#GO:0000963;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053 cytosol#GO:0005829;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC8035517|UniProtKB=A0ACM8DJU0 A0ACM8DJU0 LOC8035517 PTHR16007:SF15 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B-LIKE IXOSC|EnsemblGenome=LOC120851086|UniProtKB=A0ACM8FA20 A0ACM8FA20 LOC120851086 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029933|UniProtKB=A0ACM8EPS5 A0ACM8EPS5 LOC8029933 PTHR33236:SF13 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038194|UniProtKB=A0ACM8DGP7 A0ACM8DGP7 TTLL1B PTHR12241:SF31 TUBULIN POLYGLUTAMYLASE POLYGLUTAMYLASE COMPLEX SUBUNIT TTLL1 ligase activity, forming carbon-nitrogen bonds#GO:0016879;protein binding#GO:0005515;binding#GO:0005488;catalytic activity, acting on a protein#GO:0140096;tubulin binding#GO:0015631;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824 flagellated sperm motility#GO:0030317;plasma membrane bounded cell projection assembly#GO:0120031;developmental process#GO:0032502;spermatogenesis#GO:0007283;cellular developmental process#GO:0048869;sperm axoneme assembly#GO:0007288;male gamete generation#GO:0048232;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;sexual reproduction#GO:0019953;spermatid development#GO:0007286;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;axoneme assembly#GO:0035082;multicellular organismal reproductive process#GO:0048609;developmental process involved in reproduction#GO:0003006;germ cell development#GO:0007281;microtubule-based movement#GO:0007018;cell motility#GO:0048870;reproductive process#GO:0022414;cellular component organization or biogenesis#GO:0071840;motile cilium assembly#GO:0044458;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium movement involved in cell motility#GO:0060294;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spermatid differentiation#GO:0048515;cilium movement#GO:0003341;cilium or flagellum-dependent cell motility#GO:0001539;cilium-dependent cell motility#GO:0060285;sperm flagellum assembly#GO:0120316;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;sperm motility#GO:0097722;cell differentiation#GO:0030154;cell projection organization#GO:0030030;gamete generation#GO:0007276;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;intracellular organelle#GO:0043229;cilium#GO:0005929 microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8039364|UniProtKB=A0ACM8FL14 A0ACM8FL14 LOC8039364 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120846484|UniProtKB=A0ACM8F262 A0ACM8F262 PTHR10201:SF338 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE 2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 catabolic process#GO:0009056;cellular process#GO:0009987;cellular component organization#GO:0016043;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;metabolic process#GO:0008152;extracellular structure organization#GO:0043062 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120842254|UniProtKB=A0ACM8FJF7 A0ACM8FJF7 LOC120842254 PTHR43963:SF4 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE (NADPH) oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115316492|UniProtKB=A0ACM8F1I8 A0ACM8F1I8 LOC115316492 PTHR18945:SF879 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC115319732|UniProtKB=A0ACM8EXG4 A0ACM8EXG4 LOC115319732 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325247|UniProtKB=A0ACM8E5N1 A0ACM8E5N1 LOC115325247 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028726|UniProtKB=A0ACM8E625 A0ACM8E625 Nos PTHR43410:SF1 NITRIC OXIDE SYNTHASE OXYGENASE NITRIC OXIDE SYNTHASE protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8034999|UniProtKB=A0ACM8FU29 A0ACM8FU29 LOC8034999 PTHR46280:SF3 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 2-RELATED PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY F MEMBER 1 HOMOLOG IXOSC|EnsemblGenome=LOC115308205|UniProtKB=A0ACM8EPP6 A0ACM8EPP6 LOC115308205 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115325705|UniProtKB=A0ACM8F2N6 A0ACM8F2N6 LOC115325705 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;reproductive process#GO:0022414;homologous recombination#GO:0035825;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;cell cycle process#GO:0022402;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8030868|UniProtKB=A0ACM8ED57 A0ACM8ED57 PTHR24064:SF699 SOLUTE CARRIER FAMILY 22 MEMBER ORGANIC CATION TRANSPORTER-LIKE PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115315686|UniProtKB=A0ACM8DV32 A0ACM8DV32 LOC115315686 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;neurogenesis#GO:0022008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120836135|UniProtKB=A0ACM8EMR7 A0ACM8EMR7 LOC120836135 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115330994|UniProtKB=A0ACM8FB66 A0ACM8FB66 PTHR14098:SF14 SH2 DOMAIN CONTAINING PROTEIN SH2 DOMAIN-CONTAINING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 intracellular signal transduction#GO:0035556;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120845181|UniProtKB=A0ACM8F080 A0ACM8F080 LOC120845181 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8031649|UniProtKB=A0ACM8G1B6 A0ACM8G1B6 slo PTHR10027:SF33 CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1A-RELATED transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;calcium-activated potassium channel activity#GO:0015269;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion-gated channel activity#GO:0022839;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC121836715|UniProtKB=A0ACM8FZI2 A0ACM8FZI2 LOC121836715 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849828|UniProtKB=A0ACM8F8V0 A0ACM8F8V0 LOC120849828 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8041490|UniProtKB=A0ACM8DKP9 A0ACM8DKP9 LOC8041490 PTHR16024:SF28 XK-RELATED PROTEIN XK-RELATED PROTEIN execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization#GO:0016043;endocytosis#GO:0006897;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane invagination#GO:0010324;apoptotic cell clearance#GO:0043277;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;import into cell#GO:0098657;cell death#GO:0008219;programmed cell death#GO:0012501;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;localization#GO:0051179;anatomical structure development#GO:0048856;macromolecule localization#GO:0033036;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;lipid transport#GO:0006869;developmental process#GO:0032502;transport#GO:0006810;phagocytosis#GO:0006909;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8033412|UniProtKB=A0ACM8DHX4 A0ACM8DHX4 zuc PTHR43856:SF3 CARDIOLIPIN HYDROLASE MITOCHONDRIAL CARDIOLIPIN HYDROLASE nuclease activity#GO:0004518;hydrolase activity#GO:0016787;lipase activity#GO:0016298;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;oogenesis#GO:0048477;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;gamete generation#GO:0007276;cell differentiation#GO:0030154;cell development#GO:0048468;cellular process involved in reproduction in multicellular organism#GO:0022412;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;developmental process involved in reproduction#GO:0003006;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;germ cell development#GO:0007281;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;RNA biosynthetic process#GO:0032774;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;anatomical structure development#GO:0048856;multicellular organismal reproductive process#GO:0048609 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;outer membrane#GO:0019867;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC8031394|UniProtKB=A0ACM8ENP2 A0ACM8ENP2 LOC8031394 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC120844000|UniProtKB=A0ACM8EYI0 A0ACM8EYI0 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025320|UniProtKB=A0ACM8DJ65 A0ACM8DJ65 LOC8025320 PTHR11232:SF2 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER FI05246P protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120846713|UniProtKB=A0ACM8FG52 A0ACM8FG52 LOC120846713 PTHR45080:SF8 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE 1 ISOFORM X1 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;cell junction organization#GO:0034330;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;somatodendritic compartment#GO:0036477;neuronal cell body#GO:0043025;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;axon#GO:0030424 IXOSC|EnsemblGenome=LOC115311629|UniProtKB=A0ACM8DR05 A0ACM8DR05 TAF1B PTHR31576:SF6 TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;rRNA transcription#GO:0009303;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 General transcription by RNA polymerase I#P00022>TAF-IB#P00650 IXOSC|EnsemblGenome=LOC8043256|UniProtKB=A0ACM8DL11 A0ACM8DL11 LOC8043256 PTHR48013:SF15 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 non-receptor serine/threonine protein kinase#PC00167 Huntington disease#P00029>SEK-1#P00792;Integrin signalling pathway#P00034>MEK#P00925;Apoptosis signaling pathway#P00006>SEK1#P00266;Angiogenesis#P00005>JNKK1#P00199;EGF receptor signaling pathway#P00018>MKK4,7#P00555;FGF signaling pathway#P00021>MKK4,7#P00637;Integrin signalling pathway#P00034>Jnk#P00951;Gonadotropin-releasing hormone receptor pathway#P06664>MKK4/7#P06760;FAS signaling pathway#P00020>MKK4#P00610;Ras Pathway#P04393>MKK4/7#P04565;p38 MAPK pathway#P05918>MKK4#P06034;Toll receptor signaling pathway#P00054>MKK4#P01366;Huntington disease#P00029>MAPKK4#P00787;Oxidative stress response#P00046>MKK4#P01138;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 IXOSC|EnsemblGenome=LOC8051036|UniProtKB=A0ACM8EAC0 A0ACM8EAC0 LOC8051036 PTHR10972:SF200 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN-RELATED PROTEIN 9 binding#GO:0005488;sterol binding#GO:0032934;lipid binding#GO:0008289;steroid binding#GO:0005496 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8053335|UniProtKB=A0ACM8DXW2 A0ACM8DXW2 LOC8053335 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC121047656|UniProtKB=A0ACM8G568 A0ACM8G568 LOC121047656 PTHR10926:SF0 CELL CYCLE CONTROL PROTEIN 50 CELL DIVISION CYCLE 50, ISOFORM A enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;lipid transport#GO:0006869;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;macromolecule localization#GO:0033036;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8031593|UniProtKB=A0ACM8DMM2 A0ACM8DMM2 LOC8031593 PTHR24067:SF3 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G1 transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842 catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 IXOSC|EnsemblGenome=LOC115325288|UniProtKB=A0ACM8F8F2 A0ACM8F8F2 LOC115325288 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115313152|UniProtKB=A0ACM8DSS5 A0ACM8DSS5 LOC115313152 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 IXOSC|EnsemblGenome=LOC120842243|UniProtKB=A0ACM8ETE1 A0ACM8ETE1 LOC120842243 PTHR28643:SF1 SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG SWI5-DEPENDENT RECOMBINATION DNA REPAIR PROTEIN 1 HOMOLOG transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 double-strand break repair#GO:0006302;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;response to stress#GO:0006950;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;DNA repair#GO:0006281;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;recombinational repair#GO:0000725;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8043864|UniProtKB=A0ACM8E216 A0ACM8E216 Wdr92 PTHR10971:SF2 MRNA EXPORT FACTOR AND BUB3 DYNEIN AXONEMAL ASSEMBLY FACTOR 10 ubiquitin binding#GO:0043130;binding#GO:0005488;protein binding#GO:0005515 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8041272|UniProtKB=A0ACM8FFH4 A0ACM8FFH4 PTHR12533:SF7 NFAT NUCLEAR FACTOR OF ACTIVATED T-CELLS 5 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115319964|UniProtKB=A0ACM8F833 A0ACM8F833 LOC115319964 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120843558|UniProtKB=A0ACM8EW65 A0ACM8EW65 LOC120843558 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838310|UniProtKB=A0ACM8EKI1 A0ACM8EKI1 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115326149|UniProtKB=A0ACM8EXN2 A0ACM8EXN2 LOC115326149 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120848659|UniProtKB=A0ACM8F5C3 A0ACM8F5C3 LOC120848659 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317888|UniProtKB=A0ACM8DXH7 A0ACM8DXH7 LOC115317888 PTHR10858:SF23 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE II catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 catabolic process#GO:0009056;cellular component organization#GO:0016043;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;execution phase of apoptosis#GO:0097194;cell death#GO:0008219;apoptotic process#GO:0006915;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC120842477|UniProtKB=A0ACM8ETX2 A0ACM8ETX2 LOC120842477 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313150|UniProtKB=A0ACM8F0R1 A0ACM8F0R1 LOC115313150 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023226|UniProtKB=A0ACM8EM33 A0ACM8EM33 LOC8023226 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 IXOSC|EnsemblGenome=LOC115333047|UniProtKB=A0ACM8EEZ1 A0ACM8EEZ1 LOC115333047 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8036505|UniProtKB=A0ACM8DJZ8 A0ACM8DJZ8 LOC8036505 PTHR12561:SF3 LIPOATE-PROTEIN LIGASE LIPOYL AMIDOTRANSFERASE LIPT1, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8035942|UniProtKB=A0ACM8DNN8 A0ACM8DNN8 PTHR16112:SF22 METHYL-CPG BINDING PROTEIN, DROSOPHILA PWWP DOMAIN-CONTAINING 2B chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121835080|UniProtKB=A0ACM8FST6 A0ACM8FST6 LOC121835080 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115314759|UniProtKB=A0ACM8FSB0 A0ACM8FSB0 LOC115314759 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836218|UniProtKB=A0ACM8FZ94 A0ACM8FZ94 LOC121836218 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115333200|UniProtKB=A0ACM8EEN8 A0ACM8EEN8 LOC115333200 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311390|UniProtKB=A0ACM8EN01 A0ACM8EN01 LOC115311390 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115333106|UniProtKB=A0ACM8EGJ7 A0ACM8EGJ7 LOC115333106 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120845416|UniProtKB=A0ACM8FID3 A0ACM8FID3 LOC120845416 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040664|UniProtKB=A0ACM8DS82 A0ACM8DS82 LOC8040664 PTHR15576:SF1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 RIBITOL-5-PHOSPHATE XYLOSYLTRANSFERASE 1 xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;catalytic activity#GO:0003824;transferase activity#GO:0016740 biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8053475|UniProtKB=A0ACM8E2E9 A0ACM8E2E9 LOC8053475 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267 transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8037449|UniProtKB=A0ACM8G3B1 A0ACM8G3B1 LOC8037449 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115310975|UniProtKB=A0ACM8ESB0 A0ACM8ESB0 LOC115310975 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316683|UniProtKB=A0ACM8DWM4 A0ACM8DWM4 PTHR22930:SF289 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026473|UniProtKB=A0ACM8DQ88 A0ACM8DQ88 DNApol-alpha73 PTHR23061:SF12 DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT DNA POLYMERASE ALPHA SUBUNIT B DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139 replisome#GO:0030894;nuclear DNA-directed RNA polymerase complex#GO:0055029;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;protein-DNA complex#GO:0032993;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 DNA-directed DNA polymerase#PC00018;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121837591|UniProtKB=A0ACM8G452 A0ACM8G452 LOC121837591 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502;post-embryonic development#GO:0009791;circulatory system development#GO:0072359;heart development#GO:0007507;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular process#GO:0009987 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115323184|UniProtKB=A0ACM8ELP8 A0ACM8ELP8 LOC115323184 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115325699|UniProtKB=A0ACM8ERD8 A0ACM8ERD8 LOC115325699 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8044007|UniProtKB=A0ACM8DL63 A0ACM8DL63 LOC8044007 PTHR45896:SF1 N-ALPHA-ACETYLTRANSFERASE 30 N-ALPHA-ACETYLTRANSFERASE 30 N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;protein N-acyltransferase activity#GO:0140186;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596 acetyltransferase complex#GO:1902493;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transferase#PC00220;acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8027683|UniProtKB=A0ACM8F2K9 A0ACM8F2K9 LOC8027683 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120837342|UniProtKB=A0ACM8EHS4 A0ACM8EHS4 LOC120837342 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8039326|UniProtKB=A0ACM8DKC3 A0ACM8DKC3 LOC8039326 PTHR24377:SF1039 IP01015P-RELATED SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115315012|UniProtKB=A0ACM8FZ48 A0ACM8FZ48 LOC115315012 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8050847|UniProtKB=A0ACM8EC08 A0ACM8EC08 LOC8050847 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120847666|UniProtKB=A0ACM8F3L9 A0ACM8F3L9 NC2beta PTHR46138:SF1 PROTEIN DR1 PROTEIN DR1 protein binding#GO:0005515;binding#GO:0005488;transcription factor binding#GO:0008134 cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 IXOSC|EnsemblGenome=LOC115320469|UniProtKB=A0ACM8E056 A0ACM8E056 Mccc2 PTHR22855:SF13 ACETYL, PROPIONYL, PYRUVATE, AND GLUTACONYL CARBOXYLASE-RELATED METHYLCROTONOYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC120837051|UniProtKB=A0ACM8EGE6 A0ACM8EGE6 LOC120837051 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043780|UniProtKB=A0ACM8DGX8 A0ACM8DGX8 LOC8043780 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115309289|UniProtKB=A0ACM8DNM2 A0ACM8DNM2 LOC115309289 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121837460|UniProtKB=A0ACM8G3M7 A0ACM8G3M7 LOC121837460 PTHR46187:SF3 ALKALINE CERAMIDASE 3 ALKALINE CERAMIDASE 3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;sphingoid biosynthetic process#GO:0046520;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120849168|UniProtKB=A0ACM8FP31 A0ACM8FP31 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036941|UniProtKB=A0ACM8FUX7 A0ACM8FUX7 LOC8036941 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC8041198|UniProtKB=A0ACM8DNQ6 A0ACM8DNQ6 Nprl3 PTHR13153:SF5 CGTHBA PROTEIN -14 GENE PROTEIN GATOR1 COMPLEX PROTEIN NPRL3 positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;negative regulation of TORC1 signaling#GO:1904262;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794 protein-containing complex#GO:0032991;Seh1-associated complex#GO:0035859 IXOSC|EnsemblGenome=LOC115319623|UniProtKB=A0ACM8E048 A0ACM8E048 LOC115319623 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115310641|UniProtKB=A0ACM8DPY5 A0ACM8DPY5 LOC115310641 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC121045560|UniProtKB=A0ACM8FVN0 A0ACM8FVN0 LOC121045560 PTHR45632:SF36 LD33804P RING ZINC FINGER-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053273|UniProtKB=A0ACM8EID8 A0ACM8EID8 PTHR10654:SF18 CAS SCAFFOLDING PROTEIN BREAST CANCER ANTI-ESTROGEN RESISTANCE PROTEIN 1 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell motility#GO:0048870;cell migration#GO:0016477;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC121833589|UniProtKB=A0ACM8FLH4 A0ACM8FLH4 LOC121833589 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040551|UniProtKB=A0ACM8F5N7 A0ACM8F5N7 LOC8040551 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115309119|UniProtKB=A0ACM8F173 A0ACM8F173 LOC115309119 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8035833|UniProtKB=A0ACM8FYQ0 A0ACM8FYQ0 spt4 PTHR12882:SF1 SUPPRESSOR OF TY 4 TRANSCRIPTION ELONGATION FACTOR SPT4 binding#GO:0005488;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;RNA polymerase core enzyme binding#GO:0043175 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC120837105|UniProtKB=A0ACM8G084 A0ACM8G084 LOC120837105 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8053880|UniProtKB=A0ACM8DLP1 A0ACM8DLP1 LOC8053880 PTHR12976:SF0 RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE DELTA-SUBUNIT RETINAL ROD RHODOPSIN-SENSITIVE CGMP 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT DELTA intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC115316502|UniProtKB=A0ACM8DVY3 A0ACM8DVY3 PTHR21678:SF0 GROWTH INHIBITION AND DIFFERENTIATION RELATED PROTEIN 88 C3H1-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041098|UniProtKB=A0ACM8EX76 A0ACM8EX76 LOC8041098 PTHR11679:SF71 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 2 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC121835991|UniProtKB=A0ACM8FXH8 A0ACM8FXH8 LOC121835991 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115308415|UniProtKB=A0ACM8EPJ2 A0ACM8EPJ2 LOC115308415 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841621|UniProtKB=A0ACM8ES53 A0ACM8ES53 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115318717|UniProtKB=A0ACM8F7L9 A0ACM8F7L9 LOC115318717 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838453|UniProtKB=A0ACM8EJB4 A0ACM8EJB4 LOC120838453 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042303|UniProtKB=A0ACM8ED45 A0ACM8ED45 U4-U6-60K PTHR19846:SF0 WD40 REPEAT PROTEIN U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP4 RNA processing factor#PC00147;RNA splicing factor#PC00148 mRNA splicing#P00058>U6#P01473;mRNA splicing#P00058>U4#P01476 IXOSC|EnsemblGenome=LOC115315023|UniProtKB=A0ACM8DUY0 A0ACM8DUY0 LOC115315023 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8043258|UniProtKB=A0ACM8DL36 A0ACM8DL36 RpS9 PTHR11831:SF5 30S 40S RIBOSOMAL PROTEIN SMALL RIBOSOMAL SUBUNIT PROTEIN US4 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;binding#GO:0005488 ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121835227|UniProtKB=A0ACM8FTG5 A0ACM8FTG5 LOC121835227 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841790|UniProtKB=A0ACM8ETH9 A0ACM8ETH9 LOC120841790 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115310182|UniProtKB=A0ACM8EXE9 A0ACM8EXE9 LOC115310182 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837003|UniProtKB=A0ACM8G2H8 A0ACM8G2H8 LOC121837003 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844842|UniProtKB=A0ACM8EZW3 A0ACM8EZW3 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8053772|UniProtKB=A0ACM8F331 A0ACM8F331 LOC8053772 PTHR22951:SF115 CLATHRIN ASSEMBLY PROTEIN PHOSPHATIDYLINOSITOL-BINDING CLATHRIN ASSEMBLY PROTEIN LAP protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;lipid binding#GO:0008289;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;SNARE binding#GO:0000149;clathrin binding#GO:0030276;phospholipid binding#GO:0005543 organelle organization#GO:0006996;cellular component organization#GO:0016043;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;membrane organization#GO:0061024;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900 intracellular membrane-bounded organelle#GO:0043231;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;synaptic vesicle#GO:0008021;vesicle#GO:0031982;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane region#GO:0098590;cell periphery#GO:0071944;presynapse#GO:0098793;secretory vesicle#GO:0099503;membrane#GO:0016020;extrinsic component of plasma membrane#GO:0019897;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;synaptic membrane#GO:0097060;clathrin-coated vesicle#GO:0030136 vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC8027421|UniProtKB=A0ACM8DJ17 A0ACM8DJ17 LOC8027421 PTHR12592:SF0 ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033777|UniProtKB=A0ACM8DIA6 A0ACM8DIA6 Surf4 PTHR23427:SF1 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 4 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8040899|UniProtKB=A0ACM8DQ44 A0ACM8DQ44 calypso PTHR10589:SF28 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE BAP1 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC115317095|UniProtKB=A0ACM8DX74 A0ACM8DX74 LOC115317095 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC121836542|UniProtKB=A0ACM8FZ22 A0ACM8FZ22 LOC121836542 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8036822|UniProtKB=A0ACM8DXP5 A0ACM8DXP5 LOC8036822 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 reductase#PC00198 IXOSC|EnsemblGenome=LOC8032952|UniProtKB=A0ACM8E479 A0ACM8E479 LOC8032952 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220 IXOSC|EnsemblGenome=LOC8038862|UniProtKB=A0ACM8F5X1 A0ACM8F5X1 LOC8038862 PTHR43782:SF5 ARGINASE ARGINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;metal ion binding#GO:0046872;hydrolase activity#GO:0016787;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914 cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115325074|UniProtKB=A0ACM8FZT5 A0ACM8FZT5 LOC115325074 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120841522|UniProtKB=A0ACM8ERG2 A0ACM8ERG2 LOC120841522 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026408|UniProtKB=A0ACM8EAJ5 A0ACM8EAJ5 LOC8026408 PTHR11097:SF9 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP43 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;ribonucleoprotein complex biogenesis#GO:0022613;snRNA 3'-end processing#GO:0034472;negative regulation of metabolic process#GO:0009892;maturation of 5.8S rRNA#GO:0000460;mRNA metabolic process#GO:0016071;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule catabolic process#GO:0009057;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;rRNA processing#GO:0006364;snRNA metabolic process#GO:0016073;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nuclear mRNA surveillance#GO:0071028;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC120840608|UniProtKB=A0ACM8EPF7 A0ACM8EPF7 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115321576|UniProtKB=A0ACM8F4B8 A0ACM8F4B8 LOC115321576 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8034122|UniProtKB=A0ACM8DIZ8 A0ACM8DIZ8 LOC8034122 PTHR45986:SF1 ZINC FINGER MATRIN-TYPE PROTEIN 2 ZINC FINGER MATRIN-TYPE PROTEIN 2 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 U4/U6 x U5 tri-snRNP complex#GO:0046540;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8051596|UniProtKB=A0ACM8DLY9 A0ACM8DLY9 LOC8051596 PTHR11504:SF9 CYTOCHROME C OXIDASE POLYPEPTIDE VIA CYTOCHROME C OXIDASE SUBUNIT 6A-LIKE enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;mitochondrial electron transport, cytochrome c to oxygen#GO:0006123;metabolic process#GO:0008152;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900 oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex IV#GO:0045277;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidase#PC00175 IXOSC|EnsemblGenome=LOC8051361|UniProtKB=A0ACM8E9H8 A0ACM8E9H8 LOC8051361 PTHR12791:SF37 GOLGI SNARE BET1-RELATED BET1-LIKE PROTEIN SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cytosolic transport#GO:0016482;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;localization#GO:0051179;cellular localization#GO:0051641;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;regulation of localization#GO:0032879;regulation of transport#GO:0051049;endosomal transport#GO:0016197;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796 SNARE protein#PC00034 IXOSC|EnsemblGenome=LOC8024508|UniProtKB=A0ACM8EBA4 A0ACM8EBA4 Ada3 PTHR13556:SF2 TRANSCRIPTIONAL ADAPTER 3-RELATED TRANSCRIPTIONAL ADAPTER 3 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;SAGA complex#GO:0000124;chromatin#GO:0000785 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8023793|UniProtKB=A0ACM8F4U2 A0ACM8F4U2 LOC8023793 PTHR43999:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 DNAJ HOMOLOG SUBFAMILY C MEMBER 2 binding#GO:0005488;protein binding#GO:0005515;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;protein-folding chaperone binding#GO:0051087;heat shock protein binding#GO:0031072;Hsp70 protein binding#GO:0030544 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121835350|UniProtKB=A0ACM8FU68 A0ACM8FU68 LOC121835350 PTHR13233:SF0 MICROSPHERULE PROTEIN 1 MICROSPHERULE PROTEIN 1 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 chromosome#GO:0005694;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;NSL complex#GO:0044545;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8053548|UniProtKB=A0ACM8DL87 A0ACM8DL87 LOC8053548 PTHR44156:SF21 SUPERNUMERARY LIMBS, ISOFORM B-RELATED PROTEASOMAL ATPASE-ASSOCIATED FACTOR 1 IXOSC|EnsemblGenome=LOC8025905|UniProtKB=A0ACM8FHE5 A0ACM8FHE5 LOC8025905 PTHR39077:SF1 DUF4793 DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE APD1-4 MIDDLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843531|UniProtKB=A0ACM8EWE2 A0ACM8EWE2 LOC120843531 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8033550|UniProtKB=A0ACM8FZ27 A0ACM8FZ27 LOC8033550 PTHR47537:SF9 CUBILIN CUBILIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC121837196|UniProtKB=A0ACM8G414 A0ACM8G414 LOC121837196 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC115311572|UniProtKB=A0ACM8DQV5 A0ACM8DQV5 LOC115311572 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC8031004|UniProtKB=A0ACM8E8F9 A0ACM8E8F9 LOC8031004 PTHR15715:SF52 CENTROSOMAL PROTEIN OF 170 KDA SARCOLEMMAL MEMBRANE-ASSOCIATED PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 protein-containing complex#GO:0032991 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8039413|UniProtKB=A0ACM8G1J9 A0ACM8G1J9 Fdh PTHR43880:SF12 ALCOHOL DEHYDROGENASE ALCOHOL DEHYDROGENASE CLASS-3 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NAD+) activity#GO:0004022;zinc ion binding#GO:0008270;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 metabolic process#GO:0008152;response to chemical#GO:0042221;aldehyde catabolic process#GO:0046185;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;cellular response to oxygen-containing compound#GO:1901701;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;cellular detoxification of aldehyde#GO:0110095;cellular response to stimulus#GO:0051716 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121836060|UniProtKB=A0ACM8FX04 A0ACM8FX04 LOC121836060 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053573|UniProtKB=A0ACM8DL90 A0ACM8DL90 LOC8053573 PTHR24073:SF128 DRAB5-RELATED RAB-LIKE PROTEIN 3 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC8051746|UniProtKB=A0ACM8E730 A0ACM8E730 LOC8051746 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG deaminase activity#GO:0019239;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824 negative regulation of protein metabolic process#GO:0051248;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;deaminase#PC00088;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115329856|UniProtKB=A0ACM8F849 A0ACM8F849 LOC115329856 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028651|UniProtKB=A0ACM8DN77 A0ACM8DN77 LOC8028651 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8036520|UniProtKB=A0ACM8EI40 A0ACM8EI40 LOC8036520 PTHR10159:SF528 DUAL SPECIFICITY PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;negative regulation of intracellular signal transduction#GO:1902532;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 IXOSC|EnsemblGenome=LOC8035372|UniProtKB=A0ACM8DM66 A0ACM8DM66 faf PTHR24006:SF925 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITINYL HYDROLASE 1 cysteine-type deubiquitinase activity#GO:0004843;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;cell motility#GO:0048870;cell migration#GO:0016477;cellular process#GO:0009987;regulation of protein stability#GO:0031647 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115309892|UniProtKB=A0ACM8DP17 A0ACM8DP17 LOC115309892 PTHR13390:SF0 LIPASE LIPID DROPLET-ASSOCIATED HYDROLASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular component organization#GO:0016043;lipid droplet organization#GO:0034389;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8032330|UniProtKB=A0ACM8E2B0 A0ACM8E2B0 LOC8032330 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC115315975|UniProtKB=A0ACM8FH29 A0ACM8FH29 LOC115315975 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115325538|UniProtKB=A0ACM8ERD1 A0ACM8ERD1 LOC115325538 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120842212|UniProtKB=A0ACM8ET95 A0ACM8ET95 LOC120842212 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115319612|UniProtKB=A0ACM8FHV6 A0ACM8FHV6 LOC121836167 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038840|UniProtKB=A0ACM8FV21 A0ACM8FV21 LOC8038840 PTHR43568:SF1 P PROTEIN CITRATE TRANSPORTER-LIKE DOMAIN-CONTAINING PROTEIN-RELATED transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115314826|UniProtKB=A0ACM8ETL1 A0ACM8ETL1 LOC115314826 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8029892|UniProtKB=A0ACM8E9X9 A0ACM8E9X9 LOC8029892 PTHR19308:SF14 PHOSPHATIDYLCHOLINE TRANSFER PROTEIN START DOMAIN-CONTAINING PROTEIN 10 IXOSC|EnsemblGenome=LOC120839101|UniProtKB=A0ACM8EKR7 A0ACM8EKR7 LOC120839101 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8035973|UniProtKB=A0ACM8EDW4 A0ACM8EDW4 temp PTHR11129:SF3 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN PRENYLTRANSFERASE ALPHA SUBUNIT REPEAT-CONTAINING PROTEIN 1 prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8040738|UniProtKB=A0ACM8DH25 A0ACM8DH25 RpS26 PTHR12538:SF0 40S RIBOSOMAL PROTEIN S26 40S RIBOSOMAL PROTEIN S26 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;mRNA binding#GO:0003729 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC115323297|UniProtKB=A0ACM8F6S2 A0ACM8F6S2 LOC115323297 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8052939|UniProtKB=A0ACM8DGM8 A0ACM8DGM8 LOC8052939 PTHR10900:SF126 PERIOSTIN-RELATED MUCIN-5AC-RELATED protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;external encapsulating structure organization#GO:0045229 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120837851|UniProtKB=A0ACM8EIE5 A0ACM8EIE5 LOC120837851 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029494|UniProtKB=A0ACM8F2H7 A0ACM8F2H7 LOC8029494 PTHR22948:SF15 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 6 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8029528|UniProtKB=A0ACM8G2H7 A0ACM8G2H7 LOC8029528 PTHR24198:SF206 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND SOCS BOX PROTEIN 3 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115320179|UniProtKB=A0ACM8E0R8 A0ACM8E0R8 PTHR11472:SF34 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER REGULATOR OF TELOMERE ELONGATION HELICASE 1 macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;nucleotide binding#GO:0000166;helicase activity#GO:0004386;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;nucleic acid conformation isomerase activity#GO:0120545;carbohydrate derivative binding#GO:0097367;DNA helicase activity#GO:0003678;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;catalytic activity, acting on DNA#GO:0140097;enzyme binding#GO:0019899;ATP-dependent activity#GO:0140657;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of cellular component organization#GO:0051129;negative regulation of DNA recombination#GO:0045910;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of double-strand break repair#GO:2000779;telomere organization#GO:0032200;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;chromosome organization#GO:0051276;regulation of telomere maintenance#GO:0032204;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of metabolic process#GO:0009892;regulation of cellular component organization#GO:0051128;regulation of double-strand break repair via homologous recombination#GO:0010569;regulation of DNA recombination#GO:0000018;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular response to stress#GO:0080135;cellular process#GO:0009987;organelle organization#GO:0006996;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8025049|UniProtKB=A0ACM8F2N1 A0ACM8F2N1 LOC8025049 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC121837830|UniProtKB=A0ACM8G500 A0ACM8G500 LOC121837830 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8028727|UniProtKB=A0ACM8DH52 A0ACM8DH52 LOC8028727 PTHR21184:SF6 MENORIN (DENDRITIC BRANCHING PROTEIN) MENORIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC120843053|UniProtKB=A0ACM8EV27 A0ACM8EV27 LOC120843053 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8042467|UniProtKB=A0ACM8DKX3 A0ACM8DKX3 LOC8042467 PTHR11929:SF249 ALPHA- 1,3 -FUCOSYLTRANSFERASE FUCOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824;transferase activity#GO:0016740;alpha-(1->3)-fucosyltransferase activity#GO:0046920;glycosyltransferase activity#GO:0016757 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8040949|UniProtKB=A0ACM8DGM1 A0ACM8DGM1 Nup107 PTHR13003:SF2 NUP107-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP107 structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;intracellular protein localization#GO:0008104;chromosome organization#GO:0051276;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;protein transport#GO:0015031;protein import into nucleus#GO:0006606;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;cellular component organization#GO:0016043;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;gene expression#GO:0010467 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nuclear pore outer ring#GO:0031080;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC120850169|UniProtKB=A0ACM8F9G2 A0ACM8F9G2 LOC120850169 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120841358|UniProtKB=A0ACM8ERD0 A0ACM8ERD0 LOC120841358 PTHR10454:SF232 CASPASE CASPASE-8 peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;programmed cell death#GO:0012501;regulation of programmed cell death#GO:0043067;regulation of neuron apoptotic process#GO:0043523;biological regulation#GO:0065007;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;positive regulation of neuron apoptotic process#GO:0043525;positive regulation of apoptotic process#GO:0043065 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115314707|UniProtKB=A0ACM8FME8 A0ACM8FME8 LOC115314707 PTHR32086:SF0 FANCONI ANEMIA GROUP D2 PROTEIN FANCONI ANEMIA GROUP D2 PROTEIN enzyme binding#GO:0019899;binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;homologous recombination#GO:0035825;sexual reproduction#GO:0019953;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;homologous chromosome segregation#GO:0045143;negative regulation of biological process#GO:0048519;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;meiotic chromosome segregation#GO:0045132;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;mitotic DNA damage checkpoint signaling#GO:0044773;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;cell communication#GO:0007154;organelle fission#GO:0048285;intracellular signal transduction#GO:0035556;response to stress#GO:0006950;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;homologous chromosome pairing at meiosis#GO:0007129;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;DNA recombination#GO:0006310;chromosome segregation#GO:0007059;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;signaling#GO:0023052;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930 intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC120848219|UniProtKB=A0ACM8F5E0 A0ACM8F5E0 LOC120848219 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834207|UniProtKB=A0ACM8FQF4 A0ACM8FQF4 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;response to stimulus#GO:0050896;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974;reproductive process#GO:0022414;homologous recombination#GO:0035825;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8024933|UniProtKB=A0ACM8G8G1 A0ACM8G8G1 LOC8024933 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115319367|UniProtKB=A0ACM8F1R1 A0ACM8F1R1 LOC115319367 PTHR46186:SF2 CYSTATIN CYSTATIN-RELATED endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115308943|UniProtKB=A0ACM8EKQ3 A0ACM8EKQ3 LOC115308943 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115312711|UniProtKB=A0ACM8DS43 A0ACM8DS43 LOC115312711 PTHR46609:SF6 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN EXONUCLEASE, PHAGE-TYPE_RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8042300|UniProtKB=A0ACM8F947 A0ACM8F947 LOC8042300 PTHR10083:SF390 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED PAPILIN enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120843730|UniProtKB=A0ACM8EWW5 A0ACM8EWW5 LOC120843730 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120848864|UniProtKB=A0ACM8F6L8 A0ACM8F6L8 LOC120848864 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8043968|UniProtKB=A0ACM8ENQ3 A0ACM8ENQ3 LOC8043968 PTHR45679:SF10 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 biological regulation#GO:0065007;carbohydrate derivative metabolic process#GO:1901135;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule metabolic process#GO:0043170;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;ERAD pathway#GO:0036503;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein metabolic process#GO:0019538;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to oxygen-containing compound#GO:1901700 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC120839025|UniProtKB=A0ACM8EL43 A0ACM8EL43 LOC120839025 PTHR11999:SF68 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE HISTIDINE DECARBOXYLASE carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;amine metabolic process#GO:0009308;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144;decarboxylase#PC00089 CCKR signaling map#P06959>HDC#G07262;CCKR signaling map#P06959>HDC#G06969;Histamine synthesis#P04387>Histidine decarboxylase#P04493 IXOSC|EnsemblGenome=LOC8044080|UniProtKB=A0ACM8EU63 A0ACM8EU63 atms PTHR23188:SF12 RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG RNA POLYMERASE II-ASSOCIATED FACTOR 1 HOMOLOG binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;chromatin binding#GO:0003682;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880 IXOSC|EnsemblGenome=LOC8024926|UniProtKB=A0ACM8DNQ1 A0ACM8DNQ1 LOC8024926 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120843530|UniProtKB=A0ACM8EWC3 A0ACM8EWC3 LOC120843530 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC8042659|UniProtKB=A0ACM8E8Y0 A0ACM8E8Y0 Sap130 PTHR13497:SF3 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP130 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605 nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;Sin3-type complex#GO:0070822;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC115314754|UniProtKB=A0ACM8DU23 A0ACM8DU23 LOC115314754 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8025108|UniProtKB=A0ACM8DQ57 A0ACM8DQ57 LOC8025108 PTHR15665:SF1 ASTEROID PROTEIN SINGLE-STRAND DNA ENDONUCLEASE ASTE1 IXOSC|EnsemblGenome=LOC8054002|UniProtKB=A0ACM8DMK1 A0ACM8DMK1 eIF3m PTHR15350:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT M translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;translational initiation#GO:0006413;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 eukaryotic translation initiation factor 3 complex#GO:0005852;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115317577|UniProtKB=A0ACM8FMV9 A0ACM8FMV9 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039131|UniProtKB=A0ACM8DKB4 A0ACM8DKB4 LOC8039131 PTHR45902:SF3 LATROPHILIN RECEPTOR-LIKE PROTEIN A METHUSELAH 15-LIKE PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8052807|UniProtKB=A0ACM8DW43 A0ACM8DW43 LOC8052807 PTHR24104:SF63 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED RING-TYPE DOMAIN-CONTAINING PROTEIN acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8051836|UniProtKB=A0ACM8EVF0 A0ACM8EVF0 LOC8051836 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121838525|UniProtKB=A0ACM8G953 A0ACM8G953 LOC121838525 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8023988|UniProtKB=A0ACM8DHT8 A0ACM8DHT8 LOC8023988 PTHR24230:SF75 G-PROTEIN COUPLED RECEPTOR ALLATOSTATIN A RECEPTOR 2, ISOFORM A molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8025127|UniProtKB=A0ACM8DJ07 A0ACM8DJ07 LOC8025127 PTHR46030:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 6 RNA_DNA DEMETHYLASE ALKBH6-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121835772|UniProtKB=A0ACM8FV38 A0ACM8FV38 LOC121835772 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120844929|UniProtKB=A0ACM8F040 A0ACM8F040 LOC120844929 PTHR24256:SF579 TRYPTASE-RELATED WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8038345|UniProtKB=A0ACM8DUQ6 A0ACM8DUQ6 mRpS10 PTHR13334:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S10 SMALL RIBOSOMAL SUBUNIT PROTEIN US10M intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115330500|UniProtKB=A0ACM8EMG2 A0ACM8EMG2 LOC115330500 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8039969|UniProtKB=A0ACM8EUW6 A0ACM8EUW6 LOC8039969 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC115311978|UniProtKB=A0ACM8EZW4 A0ACM8EZW4 LOC115311978 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8041917|UniProtKB=A0ACM8EDP7 A0ACM8EDP7 LOC8041917 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8035824|UniProtKB=A0ACM8FU24 A0ACM8FU24 Ac13E PTHR45627:SF8 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 9 phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleoside phosphate biosynthetic process#GO:1901293;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cyclic purine nucleotide metabolic process#GO:0052652;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;cyclic nucleotide biosynthetic process#GO:0009190 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 adenylate cyclase#PC00043 GABA-B receptor II signaling#P05731>AC#P05760;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 IXOSC|EnsemblGenome=LOC120844537|UniProtKB=A0ACM8EZ11 A0ACM8EZ11 LOC120844537 PTHR38709:SF1 SI:CH73-193C12.2-RELATED C-TYPE LECTIN DOMAIN-CONTAINING PROTEIN-RELATED intracellular membraneless organelle#GO:0043232;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 IXOSC|EnsemblGenome=LOC8032950|UniProtKB=A0ACM8DH94 A0ACM8DH94 CSN6 PTHR10540:SF8 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT F-RELATED COP9 SIGNALOSOME COMPLEX SUBUNIT 6 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120846874|UniProtKB=A0ACM8FIK0 A0ACM8FIK0 LOC120846874 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115331187|UniProtKB=A0ACM8F8I5 A0ACM8F8I5 LOC115331187 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038749|UniProtKB=A0ACM8E774 A0ACM8E774 LOC8038749 PTHR13507:SF0 PRKR-INTERACTING PROTEIN 1 PRKR-INTERACTING PROTEIN 1 enzyme inhibitor activity#GO:0004857;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;protein kinase regulator activity#GO:0019887;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;binding#GO:0005488;kinase binding#GO:0019900;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 IXOSC|EnsemblGenome=LOC120846391|UniProtKB=A0ACM8F1H2 A0ACM8F1H2 LOC120846391 PTHR11915:SF456 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5-LIKE protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;actin filament-based process#GO:0030029;cellular component organization#GO:0016043;organelle organization#GO:0006996 intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;membraneless organelle#GO:0043228;cell junction#GO:0030054;cytoskeleton#GO:0005856;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC121838199|UniProtKB=A0ACM8G846 A0ACM8G846 LOC121838199 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850630|UniProtKB=A0ACM8FQN2 A0ACM8FQN2 PTHR24320:SF294 RETINOL DEHYDROGENASE NADP-RETINOL DEHYDROGENASE-RELATED alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 retinoid metabolic process#GO:0001523;diterpenoid metabolic process#GO:0016101;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;lipid metabolic process#GO:0006629;hormone metabolic process#GO:0042445;biological regulation#GO:0065007;aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;isoprenoid metabolic process#GO:0006720;regulation of biological quality#GO:0065008;retinol metabolic process#GO:0042572;olefinic compound metabolic process#GO:0120254;terpenoid metabolic process#GO:0006721;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;regulation of hormone levels#GO:0010817 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115327018|UniProtKB=A0ACM8EPE6 A0ACM8EPE6 LOC115327018 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029011|UniProtKB=A0ACM8FGF4 A0ACM8FGF4 LOC8029011 PTHR19300:SF65 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115331529|UniProtKB=A0ACM8ECJ4 A0ACM8ECJ4 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8040523|UniProtKB=A0ACM8EAN5 A0ACM8EAN5 LOC8040523 PTHR46957:SF3 CYTOKINE RECEPTOR PROTEIN-TYROSINE-PHOSPHATASE transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120849406|UniProtKB=A0ACM8F6Q5 A0ACM8F6Q5 LOC120849406 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115326480|UniProtKB=A0ACM8EKT9 A0ACM8EKT9 LOC115326480 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115312422|UniProtKB=A0ACM8EPA2 A0ACM8EPA2 LOC115312422 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036175|UniProtKB=A0ACM8DVV9 A0ACM8DVV9 LOC8036175 PTHR10778:SF13 SOLUTE CARRIER FAMILY 35 MEMBER B ADENOSINE 3'-PHOSPHO 5'-PHOSPHOSULFATE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate derivative transmembrane transporter activity#GO:1901505;purine nucleotide transmembrane transporter activity#GO:0015216;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120843738|UniProtKB=A0ACM8G5P1 A0ACM8G5P1 LOC120843738 PTHR15856:SF51 PHD FINGER PROTEIN 20-RELATED PROTEIN MBD-R2 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;NSL complex#GO:0044545;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694 IXOSC|EnsemblGenome=LOC121833322|UniProtKB=A0ACM8FK60 A0ACM8FK60 LOC121833322 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8029806|UniProtKB=A0ACM8F363 A0ACM8F363 LOC8029806 PTHR21324:SF2 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED CWH43-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8043186|UniProtKB=A0ACM8DL18 A0ACM8DL18 ND-19 PTHR13344:SF0 NADH-UBIQUINONE OXIDOREDUCTASE NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 8 respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex#GO:0098803;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121047557|UniProtKB=A0ACM8FGB6 A0ACM8FGB6 LOC121047557 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024703|UniProtKB=A0ACM8EN86 A0ACM8EN86 Noc1 PTHR12048:SF0 CCAAT-BINDING FACTOR-RELATED CCAAT_ENHANCER-BINDING PROTEIN ZETA cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120836516|UniProtKB=A0ACM8FP10 A0ACM8FP10 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8038892|UniProtKB=A0ACM8EDC5 A0ACM8EDC5 LOC8038892 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040095|UniProtKB=A0ACM8EDC1 A0ACM8EDC1 LOC8040095 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 microbody#GO:0042579;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115320113|UniProtKB=A0ACM8DZW4 A0ACM8DZW4 PTHR43806:SF7 PEPTIDASE S8 MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8034742|UniProtKB=A0ACM8G594 A0ACM8G594 LOC8034742 PTHR47533:SF4 PROTEIN CBG21859 AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037761|UniProtKB=A0ACM8E0R5 A0ACM8E0R5 LOC8037761 PTHR24249:SF425 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120840738|UniProtKB=A0ACM8EPZ7 A0ACM8EPZ7 LOC120840738 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120844244|UniProtKB=A0ACM8EY66 A0ACM8EY66 LOC120844244 PTHR11945:SF866 MADS BOX PROTEIN MYOCYTE-SPECIFIC ENHANCER FACTOR 2 sequence-specific DNA binding#GO:0043565;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;protein binding#GO:0005515;histone deacetylase binding#GO:0042826;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 MADS box transcription factor#PC00250 p38 MAPK pathway#P05918>MEF#P06023;Oxidative stress response#P00046>MEF-2#P01128 IXOSC|EnsemblGenome=LOC120839853|UniProtKB=A0ACM8EMX2 A0ACM8EMX2 LOC120839853 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120842450|UniProtKB=A0ACM8ETV6 A0ACM8ETV6 LOC120842450 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC120842510|UniProtKB=A0ACM8EV32 A0ACM8EV32 LOC120842510 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120842869|UniProtKB=A0ACM8FPB6 A0ACM8FPB6 PTHR24241:SF117 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE S RECEPTOR-LIKE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8041683|UniProtKB=A0ACM8E764 A0ACM8E764 LOC8041683 PTHR19957:SF307 SYNTAXIN SYNTAXIN-1A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;membrane fusion#GO:0061025;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;exocytosis#GO:0006887;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle fusion#GO:0006906;export from cell#GO:0140352;cellular component organization#GO:0016043;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;secretion by cell#GO:0032940 intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944 SNARE protein#PC00034 Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066 IXOSC|EnsemblGenome=LOC8027158|UniProtKB=A0ACM8E809 A0ACM8E809 PTHR46465:SF2 LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG LATERAL SIGNALING TARGET PROTEIN 2 HOMOLOG regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794 cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8033786|UniProtKB=A0ACM8DQZ6 A0ACM8DQZ6 LOC8033786 PTHR36754:SF2 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 E3 UBIQUITIN-PROTEIN LIGASE TRIM37 transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;binding#GO:0005488;cytokine receptor binding#GO:0005126;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;tumor necrosis factor receptor superfamily binding#GO:0032813;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;ubiquitin-like protein ligase binding#GO:0044389;signaling receptor binding#GO:0005102;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;cellular component assembly#GO:0022607;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8030783|UniProtKB=A0ACM8DHI5 A0ACM8DHI5 Gycbeta100B PTHR45655:SF2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-1 cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;lyase activity#GO:0016829 organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;response to oxygen levels#GO:0070482;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;response to abiotic stimulus#GO:0009628;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cyclic purine nucleotide metabolic process#GO:0052652;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390 catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 guanylate cyclase#PC00114;cyclase#PC00079 Endothelin signaling pathway#P00019>Guanylate cyclase#P00581;Gonadotropin-releasing hormone receptor pathway#P06664>GC#P06726 IXOSC|EnsemblGenome=LOC120843805|UniProtKB=A0ACM8EWN8 A0ACM8EWN8 LOC120843805 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8026050|UniProtKB=A0ACM8EB85 A0ACM8EB85 LOC8026050 PTHR43104:SF2 L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8042389|UniProtKB=A0ACM8DXI4 A0ACM8DXI4 LOC8042389 PTHR12778:SF10 SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED SOLUTE CARRIER FAMILY 33 MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115320068|UniProtKB=A0ACM8EX52 A0ACM8EX52 LOC115320068 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8031347|UniProtKB=A0ACM8DI51 A0ACM8DI51 LOC8031347 PTHR10390:SF33 HOMEOBOX PROTEIN SIX PROTEIN OPTIX sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120842912|UniProtKB=A0ACM8EUS2 A0ACM8EUS2 LOC120842912 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8024287|UniProtKB=A0ACM8FZ31 A0ACM8FZ31 LOC8024287 PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023 synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC120844539|UniProtKB=A0ACM8EYL5 A0ACM8EYL5 LOC120844539 PTHR11214:SF411 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8025406|UniProtKB=A0ACM8FSX2 A0ACM8FSX2 LOC8025406 PTHR12011:SF347 ADHESION G-PROTEIN COUPLED RECEPTOR LATROPHILIN CIRL cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8031663|UniProtKB=A0ACM8DY13 A0ACM8DY13 LOC8031663 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;binding#GO:0005488 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;steroid metabolic process#GO:0008202;response to stimulus#GO:0050896;response to chemical#GO:0042221 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121834246|UniProtKB=A0ACM8FPB7 A0ACM8FPB7 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319051|UniProtKB=A0ACM8DYN9 A0ACM8DYN9 LOC115319051 PTHR23149:SF27 G PATCH DOMAIN CONTAINING PROTEIN PIN2_TERF1-INTERACTING TELOMERASE INHIBITOR 1 molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115322642|UniProtKB=A0ACM8E2A2 A0ACM8E2A2 LOC115322642 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC120836228|UniProtKB=A0ACM8FXL8 A0ACM8FXL8 LOC120836228 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115322130|UniProtKB=A0ACM8E2W7 A0ACM8E2W7 SdhD PTHR13337:SF2 SUCCINATE DEHYDROGENASE SUCCINATE DEHYDROGENASE [UBIQUINONE] CYTOCHROME B SMALL SUBUNIT, MITOCHONDRIAL tetrapyrrole binding#GO:0046906;binding#GO:0005488;small molecule binding#GO:0036094;heme binding#GO:0020037 mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;electron transport chain#GO:0022900;primary metabolic process#GO:0044238;tricarboxylic acid cycle#GO:0006099;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;respiratory chain complex#GO:0098803;respiratory chain complex II (succinate dehydrogenase)#GO:0045273;catalytic complex#GO:1902494 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8030168|UniProtKB=A0ACM8F5U0 A0ACM8F5U0 dor PTHR23323:SF29 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 18 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component organization#GO:0016043;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;localization#GO:0051179;cellular localization#GO:0051641;vacuole organization#GO:0007033;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;lysosome organization#GO:0007040;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;lytic vacuole organization#GO:0080171;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;endosome organization#GO:0007032 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle tethering complex#GO:0099023;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8030172|UniProtKB=A0ACM8FXC0 A0ACM8FXC0 LOC8030172 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115317546|UniProtKB=A0ACM8G762 A0ACM8G762 LOC115317546 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043240|UniProtKB=A0ACM8EFY3 A0ACM8EFY3 LOC8043240 PTHR23294:SF0 ET TRANSLATION PRODUCT-RELATED UNC93-LIKE PROTEIN MFSD11 IXOSC|EnsemblGenome=LOC8033840|UniProtKB=A0ACM8ECW4 A0ACM8ECW4 LOC8033840 PTHR11254:SF320 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE HECT-TYPE E3 UBIQUITIN TRANSFERASE ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of dendrite morphogenesis#GO:0048814;primary metabolic process#GO:0044238;regulation of developmental process#GO:0050793;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;regulation of dendrite development#GO:0050773;regulation of cellular process#GO:0050794;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of cell projection organization#GO:0031344;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of anatomical structure morphogenesis#GO:0022603 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8044133|UniProtKB=A0ACM8DL85 A0ACM8DL85 LOC8044133 PTHR12313:SF0 E3 UBIQUITIN-PROTEIN LIGASE RNF5-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120850240|UniProtKB=A0ACM8FZJ0 A0ACM8FZJ0 LOC120850240 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8052646|UniProtKB=A0ACM8DLZ2 A0ACM8DLZ2 LOC8052646 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8026333|UniProtKB=A0ACM8DMR0 A0ACM8DMR0 Spase22-23 PTHR12804:SF0 MICROSOMAL SIGNAL PEPTIDASE 23 KD SUBUNIT SPC22/23 SIGNAL PEPTIDASE COMPLEX SUBUNIT 3 protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;establishment of protein localization#GO:0045184;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;localization#GO:0051179;protein metabolic process#GO:0019538;protein targeting#GO:0006605;primary metabolic process#GO:0044238 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 IXOSC|EnsemblGenome=LOC121045677|UniProtKB=A0ACM8FBU6 A0ACM8FBU6 LOC121045677 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8025011|UniProtKB=A0ACM8E6E3 A0ACM8E6E3 Dgkepsilon PTHR11255:SF54 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE EPSILON kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;biological regulation#GO:0065007;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;membrane#GO:0016020 kinase#PC00137;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037835|UniProtKB=A0ACM8EB96 A0ACM8EB96 LOC8037835 PTHR11616:SF332 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;amino acid transport#GO:0006865 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115326884|UniProtKB=A0ACM8E748 A0ACM8E748 LOC115326884 PTHR12360:SF1 NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1 NF-X1-TYPE ZINC FINGER PROTEIN NFXL1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115312005|UniProtKB=A0ACM8DRQ6 A0ACM8DRQ6 eIF2Bepsilon PTHR45887:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON TRANSLATION INITIATION FACTOR EIF2B SUBUNIT EPSILON translation factor activity#GO:0180051;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;translation initiation factor binding#GO:0031369;translation initiation factor activity#GO:0003743;molecular function regulator activity#GO:0098772;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;protein binding#GO:0005515;enzyme regulator activity#GO:0030234 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120839098|UniProtKB=A0ACM8ELJ0 A0ACM8ELJ0 LOC120839098 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8035696|UniProtKB=A0ACM8ELY6 A0ACM8ELY6 MED14 PTHR12809:SF2 MEDIATOR COMPLEX SUBUNIT MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 14 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC121834464|UniProtKB=A0ACM8FR12 A0ACM8FR12 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8039463|UniProtKB=A0ACM8EG71 A0ACM8EG71 cut PTHR14043:SF18 CCAAT DISPLACEMENT PROTEIN-RELATED HOMEOBOX PROTEIN CUT transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8039060|UniProtKB=A0ACM8FD90 A0ACM8FD90 Nacalpha PTHR21713:SF4 NASCENT POLYPEPTIDE ASSOCIATED COMPLEX ALPHA SUBUNIT-RELATED GH09281P-RELATED cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC120837994|UniProtKB=A0ACM8EIX8 A0ACM8EIX8 LOC120837994 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121835625|UniProtKB=A0ACM8FWA4 A0ACM8FWA4 LOC121835625 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=ISCI006396|UniProtKB=Q964Q0 Q964Q0 PTHR45938:SF14 ACP24A4-RELATED IXOLARIS IXOSC|EnsemblGenome=LOC120837159|UniProtKB=A0ACM8G910 A0ACM8G910 LOC120837159 PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115311797|UniProtKB=A0ACM8F6B2 A0ACM8F6B2 LOC115311797 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120840190|UniProtKB=A0ACM8ENI4 A0ACM8ENI4 LOC120840190 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575 transferase#PC00220 IXOSC|EnsemblGenome=LOC115312968|UniProtKB=A0ACM8FPJ7 A0ACM8FPJ7 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025455|UniProtKB=A0ACM8DX30 A0ACM8DX30 LOC8025455 PTHR23231:SF17 GERM CELL-LESS PROTEIN GERM CELL-LESS 1, SPERMATOSIS ASSOCIATED ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8039771|UniProtKB=A0ACM8DVW7 A0ACM8DVW7 PTHR31649:SF1 AGAP009604-PA FARNESOIC ACID O-METHYL TRANSFERASE DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121833604|UniProtKB=A0ACM8FLU8 A0ACM8FLU8 LOC121833604 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8035391|UniProtKB=A0ACM8DUY7 A0ACM8DUY7 LOC8035391 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8043801|UniProtKB=A0ACM8ECC2 A0ACM8ECC2 PTHR10361:SF70 SODIUM-BILE ACID COTRANSPORTER P3 PROTEIN-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8037502|UniProtKB=A0ACM8F1M7 A0ACM8F1M7 LOC8037502 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC115309152|UniProtKB=A0ACM8DNH6 A0ACM8DNH6 LOC115309152 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8033420|UniProtKB=A0ACM8DHX7 A0ACM8DHX7 LOC8033420 PTHR21320:SF8 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11-RELATED CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX11, MITOCHONDRIAL membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115314625|UniProtKB=A0ACM8EMS7 A0ACM8EMS7 LOC115314625 PTHR24399:SF70 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115332874|UniProtKB=A0ACM8EF30 A0ACM8EF30 LOC115332874 PTHR23074:SF83 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;endosomal transport#GO:0016197;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;intracellular transport#GO:0046907;macromolecule catabolic process#GO:0009057;transport#GO:0006810;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;localization#GO:0051179;cellular localization#GO:0051641;protein metabolic process#GO:0019538;vacuole organization#GO:0007033;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;modification-dependent protein catabolic process#GO:0019941 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC8036882|UniProtKB=A0ACM8ECV7 A0ACM8ECV7 LOC8036882 PTHR23082:SF0 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 3 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription initiation#GO:0006352;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription factor TFIIIC complex#GO:0000127;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8028678|UniProtKB=A0ACM8E923 A0ACM8E923 LOC8028678 PTHR19372:SF7 SULFITE REDUCTASE SULFITE OXIDASE, MITOCHONDRIAL intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;reductase#PC00198;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8030060|UniProtKB=A0ACM8FN55 A0ACM8FN55 PTHR21119:SF5 C2 DOMAIN-CONTAINING PROTEIN C2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312886|UniProtKB=A0ACM8DSA0 A0ACM8DSA0 LOC115312886 PTHR47059:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 32 TETRATRICOPEPTIDE REPEAT PROTEIN 32 IXOSC|EnsemblGenome=LOC115327163|UniProtKB=A0ACM8ENW7 A0ACM8ENW7 LOC115327163 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120849784|UniProtKB=A0ACM8F8C0 A0ACM8F8C0 LOC120849784 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120846598|UniProtKB=A0ACM8F2T1 A0ACM8F2T1 LOC120846598 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;heart development#GO:0007507;circulatory system development#GO:0072359;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;system development#GO:0048731;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;cell adhesion#GO:0007155;developmental process#GO:0032502;post-embryonic development#GO:0009791;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8031637|UniProtKB=A0ACM8EF46 A0ACM8EF46 DNAlig3 PTHR45674:SF20 DNA LIGASE 1/3 FAMILY MEMBER DNA LIGASE 3 ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097 cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA ligase#PC00012;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8032811|UniProtKB=A0ACM8EEK4 A0ACM8EEK4 LOC8032811 PTHR11486:SF148 FIBROBLAST GROWTH FACTOR FIBROBLAST GROWTH FACTOR binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515;molecular function activator activity#GO:0140677;growth factor receptor binding#GO:0070851;signaling receptor regulator activity#GO:0030545;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;fibroblast growth factor receptor binding#GO:0005104;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;multicellular organism development#GO:0007275;regulation of MAPK cascade#GO:0043408;cell surface receptor signaling pathway#GO:0007166;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;multicellular organismal process#GO:0032501;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of locomotion#GO:0040012;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;positive regulation of MAPK cascade#GO:0043410;neurogenesis#GO:0022008;response to fibroblast growth factor#GO:0071774;regulation of cell migration#GO:0030334;developmental process#GO:0032502;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;regulation of cell motility#GO:2000145;regulation of cell population proliferation#GO:0042127;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112;intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120839668|UniProtKB=A0ACM8EMI4 A0ACM8EMI4 LOC120839668 PTHR43684:SF18 FAMILY NOT NAMED DODECENOYL-COA DELTA-ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824 monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782 IXOSC|EnsemblGenome=LOC8039901|UniProtKB=A0ACM8E2I5 A0ACM8E2I5 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8038254|UniProtKB=A0ACM8E9L2 A0ACM8E9L2 LOC8038254 PTHR22607:SF3 DELETED IN ORAL CANCER 1/CDK2-ASSOCIATED PROTEIN 1 CDK2-ASSOCIATED PROTEIN 1, ISOFORM B nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase inhibitor#PC00139;kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC120846455|UniProtKB=A0ACM8F250 A0ACM8F250 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8027094|UniProtKB=A0ACM8FT97 A0ACM8FT97 LOC8027094 PTHR10037:SF288 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM SODIUM CHANNEL PROTEIN PARA monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 system process#GO:0003008;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;sensory perception#GO:0007600;nervous system process#GO:0050877;membrane depolarization#GO:0051899;metal ion transport#GO:0030001;action potential#GO:0001508;sodium ion transport#GO:0006814;sensory perception of pain#GO:0019233 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;sodium channel complex#GO:0034706;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC115323242|UniProtKB=A0ACM8ET77 A0ACM8ET77 LOC115323242 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115328264|UniProtKB=A0ACM8E8K0 A0ACM8E8K0 mRpS16 PTHR12919:SF41 30S RIBOSOMAL PROTEIN S16 SMALL RIBOSOMAL SUBUNIT PROTEIN BS16M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120843994|UniProtKB=A0ACM8EXF2 A0ACM8EXF2 LOC120843994 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121834612|UniProtKB=A0ACM8FQ71 A0ACM8FQ71 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038029|UniProtKB=A0ACM8DRA9 A0ACM8DRA9 LOC8038029 PTHR43811:SF63 FKBP-TYPE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKPA 39 KDA FK506-BINDING NUCLEAR PROTEIN cis-trans isomerase activity#GO:0016859;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115326265|UniProtKB=A0ACM8E746 A0ACM8E746 LOC115326265 PTHR24133:SF14 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 9 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8031866|UniProtKB=A0ACM8DIT8 A0ACM8DIT8 LOC8031866 PTHR22811:SF210 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN P24-RELATED-1, ISOFORM A protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;Golgi organization#GO:0007030;cellular component organization#GO:0016043;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;endomembrane system#GO:0012505 vesicle coat protein#PC00235;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120841828|UniProtKB=A0ACM8ESH5 A0ACM8ESH5 PTHR11439:SF463 GAG-POL-RELATED RETROTRANSPOSON INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030867|UniProtKB=A0ACM8ECQ7 A0ACM8ECQ7 PTHR13742:SF17 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RE32990P-RELATED double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular developmental process#GO:0048869;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle process#GO:0010948;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8034736|UniProtKB=A0ACM8F1E2 A0ACM8F1E2 LOC8034736 PTHR11849:SF133 ETS ETS DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>ELK#P00890;Parkinson disease#P00049>Elk-1#P01233 IXOSC|EnsemblGenome=LOC121834009|UniProtKB=A0ACM8FP49 A0ACM8FP49 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8032396|UniProtKB=A0ACM8DRJ9 A0ACM8DRJ9 LOC8032396 PTHR23215:SF0 ZINC FINGER PROTEIN 207 BUB3 INTERACTING GLEBS AND ZINC FINGER DOMAIN PROTEIN, ISOFORM F nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8034107|UniProtKB=A0ACM8G8P5 A0ACM8G8P5 LOC8034107 PTHR16525:SF1 PROTEIN C12ORF4 LD27564P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115331565|UniProtKB=A0ACM8EC38 A0ACM8EC38 LOC115331565 PTHR23285:SF7 RING FINGER AND KH DOMAIN CONTAINING PROTEIN 1 LD09246P1 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120843500|UniProtKB=A0ACM8FW30 A0ACM8FW30 LOC120843500 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115327650|UniProtKB=A0ACM8F4B3 A0ACM8F4B3 LOC115327650 PTHR46473:SF28 GH08155P ELRR (EXTRACELLULAR LEUCINE-RICH REPEAT) ONLY IXOSC|EnsemblGenome=LOC121833474|UniProtKB=A0ACM8FJX6 A0ACM8FJX6 LOC121833474 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314740|UniProtKB=A0ACM8FX18 A0ACM8FX18 LOC115314740 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120846560|UniProtKB=A0ACM8F1W8 A0ACM8F1W8 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039091|UniProtKB=A0ACM8DTC6 A0ACM8DTC6 LOC8039091 PTHR11533:SF299 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787 catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8033320|UniProtKB=A0ACM8EY25 A0ACM8EY25 LOC8033320 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310225|UniProtKB=A0ACM8G232 A0ACM8G232 LOC115310225 PTHR14167:SF125 SH3 DOMAIN-CONTAINING CAP, ISOFORM AC protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8023313|UniProtKB=A0ACM8F5J1 A0ACM8F5J1 PTHR34033:SF1 AP-5 COMPLEX SUBUNIT BETA-1 AP-5 COMPLEX SUBUNIT BETA-1 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;AP-type membrane coat adaptor complex#GO:0030119;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796 IXOSC|EnsemblGenome=LOC8031112|UniProtKB=A0ACM8DVA4 A0ACM8DVA4 LOC8031112 PTHR24133:SF59 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT AND FYVE DOMAIN CONTAINING 1 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8024775|UniProtKB=A0ACM8DIP5 A0ACM8DIP5 LOC8024775 PTHR43245:SF11 BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA LD23561P IXOSC|EnsemblGenome=LOC115310235|UniProtKB=A0ACM8EH46 A0ACM8EH46 LOC115310235 PTHR11827:SF103 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SODIUM CHLORIDE COTRANSPORTER 69, ISOFORM E transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;chloride transmembrane transporter activity#GO:0015108;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;solute:sodium symporter activity#GO:0015370 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;monoatomic anion transport#GO:0006820;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115309774|UniProtKB=A0ACM8DP57 A0ACM8DP57 LOC115309774 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115309566|UniProtKB=A0ACM8F2F5 A0ACM8F2F5 LOC115309830 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835547|UniProtKB=A0ACM8FVW9 A0ACM8FVW9 LOC121835547 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028579|UniProtKB=A0ACM8FD66 A0ACM8FD66 LOC8028579 PTHR11552:SF233 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI02019P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837294|UniProtKB=A0ACM8EHZ7 A0ACM8EHZ7 LOC120837294 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026540|UniProtKB=A0ACM8E365 A0ACM8E365 LOC8026540 PTHR24347:SF456 SERINE/THREONINE-PROTEIN KINASE CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;calcium/calmodulin-dependent protein kinase activity#GO:0004683;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;calmodulin binding#GO:0005516;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8050436|UniProtKB=A0ACM8FBW4 A0ACM8FBW4 LOC8050436 PTHR11636:SF5 POU DOMAIN POU DOMAIN MOTIF 3, ISOFORM F binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC115329632|UniProtKB=A0ACM8EYC5 A0ACM8EYC5 CngA PTHR45638:SF25 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A binding#GO:0005488;nucleoside phosphate binding#GO:1901265;gated channel activity#GO:0022836;guanyl nucleotide binding#GO:0019001;monoatomic cation transmembrane transporter activity#GO:0008324;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine ribonucleotide binding#GO:0032555;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166 system process#GO:0003008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;sensory perception#GO:0007600;transport#GO:0006810;nervous system process#GO:0050877;sensory perception of chemical stimulus#GO:0007606;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;multicellular organismal process#GO:0032501;cellular process#GO:0009987 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;cation channel complex#GO:0034703;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944 ion channel#PC00133;ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8023453|UniProtKB=A0ACM8EBD3 A0ACM8EBD3 RpS30 PTHR12650:SF15 40S RIBOSOMAL PROTEIN S30/UBIQUITIN-LIKE PROTEIN FUBI RIBOSOMAL PROTEIN S30, ISOFORM A ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8031820|UniProtKB=A0ACM8DT49 A0ACM8DT49 LOC8031820 PTHR11692:SF0 BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN PURH BIFUNCTIONAL PURINE BIOSYNTHESIS PROTEIN ATIC transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;IMP metabolic process#GO:0046040;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside phosphate biosynthetic process#GO:1901293 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 De novo purine biosynthesis#P02738>AICAR transformylase#P02900;De novo purine biosynthesis#P02738>IMP cyclohydrolase#P02894 IXOSC|EnsemblGenome=LOC8031284|UniProtKB=A0ACM8G0C3 A0ACM8G0C3 LOC8031284 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120837561|UniProtKB=A0ACM8EH71 A0ACM8EH71 LOC120837561 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8033496|UniProtKB=A0ACM8E9W7 A0ACM8E9W7 LOC8033496 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115323033|UniProtKB=A0ACM8ENT5 A0ACM8ENT5 LOC115323033 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029648|UniProtKB=A0ACM8EN34 A0ACM8EN34 LOC8029648 PTHR19332:SF1 PEROXISOMAL MEMBRANE PROTEIN PEX13 PEROXISOMAL MEMBRANE PROTEIN PEX13 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;peroxisome organization#GO:0007031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;protein transport#GO:0015031;peroxisomal transport#GO:0043574 peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;transporter complex#GO:1990351;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115324238|UniProtKB=A0ACM8E3P5 A0ACM8E3P5 LOC115324238 PTHR46090:SF5 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 13B plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;protein localization to cell periphery#GO:1990778;protein localization to cilium#GO:0061512;cell projection organization#GO:0030030;protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cilium organization#GO:0044782;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cellular localization#GO:0051641;localization within membrane#GO:0051668;organelle assembly#GO:0070925 cilium#GO:0005929;cell projection membrane#GO:0031253;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;organelle#GO:0043226;ciliary membrane#GO:0060170;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8044033|UniProtKB=A0ACM8F9C9 A0ACM8F9C9 LOC8044033 PTHR14494:SF0 ALADIN/ADRACALIN/AAAS ALADIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;organelle assembly#GO:0070925;nuclear division#GO:0000280;microtubule bundle formation#GO:0001578;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;spindle assembly#GO:0051225;mitotic spindle assembly#GO:0090307;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;chromosome organization#GO:0051276 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8023135|UniProtKB=A0ACM8E7U2 A0ACM8E7U2 iPLA2-VIA PTHR24139:SF36 CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 PHOSPHOLIPASE A2 A2-type glycerophospholipase activity#GO:0004623;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;deacylase activity#GO:0160215;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;hydrolase activity#GO:0016787;lipase activity#GO:0016298;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;thiolester hydrolase activity#GO:0016790;carboxylic ester hydrolase activity#GO:0052689 regulation of lipid biosynthetic process#GO:0046890;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cellular component biogenesis#GO:0044087;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of biosynthetic process#GO:0009889;regulation of lipid metabolic process#GO:0019216 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phospholipase#PC00186;lipase#PC00143 IXOSC|EnsemblGenome=LOC120840207|UniProtKB=A0ACM8EMX5 A0ACM8EMX5 LOC120840207 PTHR13369:SF0 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832907|UniProtKB=A0ACM8G6D0 A0ACM8G6D0 LOC121832907 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024075|UniProtKB=A0ACM8FT27 A0ACM8FT27 LOC8024075 PTHR11036:SF79 SEMAPHORIN SEMAPHORIN 5C signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;signaling#GO:0023052;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;positive regulation of locomotion#GO:0040017;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon development#GO:0061564;axon guidance#GO:0007411;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 IXOSC|EnsemblGenome=LOC8024991|UniProtKB=A0ACM8DIX7 A0ACM8DIX7 LOC8024991 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120835927|UniProtKB=A0ACM8F3I6 A0ACM8F3I6 PTHR13100:SF10 CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR CELL GROWTH-REGULATING NUCLEOLAR PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;rRNA processing#GO:0006364;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;regulation of transcription by RNA polymerase II#GO:0006357;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8038568|UniProtKB=A0ACM8E1L5 A0ACM8E1L5 Pp2C1 PTHR47992:SF253 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE 1D binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;hydrolase activity#GO:0016787;protein binding#GO:0005515;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;mitogen-activated protein kinase binding#GO:0051019 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>WIP-1#G04708;p53 pathway#P00059>WIP-1#G04693;p53 pathway feedback loops 2#P04398>WIP-1#P04650 IXOSC|EnsemblGenome=LOC8023898|UniProtKB=A0ACM8FQD8 A0ACM8FQD8 LOC8023898 PTHR45993:SF6 B-CELL LYMPHOMA/LEUKEMIA 11 CHRONOPHAGE, ISOFORM K nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120843361|UniProtKB=A0ACM8G872 A0ACM8G872 LOC120843361 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 glycosidase#PC00110;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8034224|UniProtKB=A0ACM8FFN8 A0ACM8FFN8 LOC8034224 PTHR13140:SF802 MYOSIN MYOSIN 95E, ISOFORM E cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin filament-based movement#GO:0030048;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;transport#GO:0006810;actin filament-based process#GO:0030029;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin-based cell projection#GO:0098858;microvillus#GO:0005902;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC8039365|UniProtKB=A0ACM8E8M0 A0ACM8E8M0 LOC8039365 PTHR11475:SF147 OXIDASE/PEROXIDASE PEROXIDASIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC120842469|UniProtKB=A0ACM8EUZ8 A0ACM8EUZ8 LOC120842469 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120845987|UniProtKB=A0ACM8F236 A0ACM8F236 LOC120845987 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033997|UniProtKB=A0ACM8FY78 A0ACM8FY78 LOC8033997 PTHR23196:SF42 PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN PAX-INTERACTING PROTEIN 1 response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950 organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC120836004|UniProtKB=A0ACM8F8Q6 A0ACM8F8Q6 LOC120836004 PTHR15641:SF1 ELONGATOR COMPLEX PROTEIN 5 ELONGATOR COMPLEX PROTEIN 5 nucleic acid binding#GO:0003676;binding#GO:0005488;tRNA binding#GO:0000049;RNA binding#GO:0003723 gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;elongator holoenzyme complex#GO:0033588;cytosol#GO:0005829;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC120840772|UniProtKB=A0ACM8FES3 A0ACM8FES3 LOC120840772 PTHR19282:SF565 TETRASPANIN TETRASPANIN-14 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121834787|UniProtKB=A0ACM8FRI2 A0ACM8FRI2 LOC121834787 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844782|UniProtKB=A0ACM8F0P0 A0ACM8F0P0 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843269|UniProtKB=A0ACM8EVK0 A0ACM8EVK0 LOC120843269 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848347|UniProtKB=A0ACM8F5Y0 A0ACM8F5Y0 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8023491|UniProtKB=A0ACM8DUF1 A0ACM8DUF1 LOC8023491 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC115323487|UniProtKB=A0ACM8F472 A0ACM8F472 LOC115323487 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8051105|UniProtKB=A0ACM8EAM8 A0ACM8EAM8 LOC8051105 PTHR13568:SF9 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 203 intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion homeostasis#GO:0055074;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC8042219|UniProtKB=A0ACM8E240 A0ACM8E240 LOC8042219 PTHR18934:SF118 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX33 helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;ATP-dependent activity#GO:0140657 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase I#GO:0045943;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of transcription by RNA polymerase I#GO:0006356;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC121837522|UniProtKB=A0ACM8G3U3 A0ACM8G3U3 LOC121837522 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8037346|UniProtKB=A0ACM8DK35 A0ACM8DK35 LOC8037346 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 IXOSC|EnsemblGenome=LOC8027774|UniProtKB=A0ACM8EGP2 A0ACM8EGP2 LOC8027774 PTHR41158:SF2 AGAP010294-PA SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115311989|UniProtKB=A0ACM8G5E6 A0ACM8G5E6 LOC115311989 PTHR24258:SF116 SERINE PROTEASE-RELATED ACROSIN-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120839582|UniProtKB=A0ACM8ELK4 A0ACM8ELK4 LOC120839582 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8027190|UniProtKB=A0ACM8DQN7 A0ACM8DQN7 LOC8027190 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120836260|UniProtKB=A0ACM8F1S0 A0ACM8F1S0 LOC120836260 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8024628|UniProtKB=A0ACM8E8D2 A0ACM8E8D2 LOC8024628 PTHR10846:SF72 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER NCKX30C monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;antiporter activity#GO:0015297;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8030324|UniProtKB=A0ACM8F3S6 A0ACM8F3S6 LOC8030324 PTHR10671:SF82 EPITHELIAL MEMBRANE PROTEIN-RELATED FI18012P1 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8035911|UniProtKB=A0ACM8EYG2 A0ACM8EYG2 LOC8035911 PTHR12385:SF12 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8027873|UniProtKB=A0ACM8EA43 A0ACM8EA43 PTHR43028:SF5 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8044152|UniProtKB=A0ACM8G7V8 A0ACM8G7V8 LOC8044152 PTHR13069:SF21 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 TRNA (CARBOXYMETHYLURIDINE(34)-5-O)-METHYLTRANSFERASE ALKBH8 tRNA binding#GO:0000049;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723;methyltransferase activity#GO:0008168;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8052494|UniProtKB=A0ACM8FJ95 A0ACM8FJ95 LOC8052494 PTHR13906:SF16 PORCUPINE MEMBRANE-BOUND ACYLGLYCEROPHOSPHATIDYLINOSITOL O-ACYLTRANSFERASE MBOAT7 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;lipid modification#GO:0030258 cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondria-associated endoplasmic reticulum membrane contact site#GO:0044233;organelle membrane contact site#GO:0044232;membrane#GO:0016020 acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC115323772|UniProtKB=A0ACM8E392 A0ACM8E392 LOC115323772 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844543|UniProtKB=A0ACM8EYV5 A0ACM8EYV5 LOC120844543 PTHR11214:SF411 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115320355|UniProtKB=A0ACM8E026 A0ACM8E026 LOC115320355 PTHR24036:SF13 SKELETOR-RELATED PROTEIN SKELETOR, ISOFORMS D_E transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120836508|UniProtKB=A0ACM8EFA0 A0ACM8EFA0 LOC120836508 PTHR28626:SF3 SRR1-LIKE PROTEIN SRR1-LIKE PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8026436|UniProtKB=A0ACM8DSN8 A0ACM8DSN8 LOC8026436 PTHR23426:SF78 FERREDOXIN/ADRENODOXIN FERREDOXIN-2, MITOCHONDRIAL generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987;metabolic process#GO:0008152;electron transport chain#GO:0022900 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FDX#P04607 IXOSC|EnsemblGenome=LOC120845798|UniProtKB=A0ACM8G600 A0ACM8G600 LOC120845798 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115314456|UniProtKB=A0ACM8FRN2 A0ACM8FRN2 LOC115314456 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832922|UniProtKB=A0ACM8FS45 A0ACM8FS45 LOC121832922 PTHR10404:SF84 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;carboxypeptidase activity#GO:0004180;peptidase activity#GO:0008233 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120843055|UniProtKB=A0ACM8EV68 A0ACM8EV68 LOC120843055 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8041506|UniProtKB=A0ACM8E630 A0ACM8E630 LOC8041506 PTHR21208:SF1 ADP-DEPENDENT GLUCOKINASE ADP-DEPENDENT GLUCOKINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 kinase#PC00137 IXOSC|EnsemblGenome=LOC8037120|UniProtKB=A0ACM8DP94 A0ACM8DP94 LOC8037120 PTHR14677:SF45 ARSENITE INDUCUBLE RNA ASSOCIATED PROTEIN AIP-1-RELATED AN1-TYPE DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8030070|UniProtKB=A0ACM8FPT0 A0ACM8FPT0 PTHR12619:SF32 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8053361|UniProtKB=A0ACM8DLS4 A0ACM8DLS4 LOC8053361 PTHR21397:SF2 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED BPTF-ASSOCIATED CHROMATIN COMPLEX COMPONENT 1 nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;SWI/SNF superfamily-type complex#GO:0070603;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;nucleoplasm#GO:0005654;organelle#GO:0043226;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ISWI-type complex#GO:0031010 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115310231|UniProtKB=A0ACM8DPJ3 A0ACM8DPJ3 LOC115310231 PTHR11943:SF1 GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;organophosphate metabolic process#GO:0019637;hexose metabolic process#GO:0019318;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 nucleotidyltransferase#PC00174 Interleukin signaling pathway#P00036>Receptor subunit alpha#P00992;Fructose galactose metabolism#P02744>Hexose 1-P uridyltransferase#P02964 IXOSC|EnsemblGenome=LOC8039909|UniProtKB=A0ACM8E044 A0ACM8E044 LOC8039909 PTHR12625:SF0 LIPOCALIN-1 INTERACTING MEMBRANE RECEPTOR LIMR PROTEIN LILIPOD molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115326133|UniProtKB=A0ACM8EYF2 A0ACM8EYF2 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291 monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;sodium ion transport#GO:0006814;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC121834182|UniProtKB=A0ACM8FPM8 A0ACM8FPM8 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315503|UniProtKB=A0ACM8DUW2 A0ACM8DUW2 LOC115315503 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC chromatin binding#GO:0003682;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252 transferase complex#GO:1990234;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC121835225|UniProtKB=A0ACM8FS14 A0ACM8FS14 LOC121835225 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115320697|UniProtKB=A0ACM8FKM5 A0ACM8FKM5 LOC115320697 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035038|UniProtKB=A0ACM8EW24 A0ACM8EW24 Iml1 PTHR13179:SF8 DEP DOMAIN CONTAINING PROTEIN 5 GATOR1 COMPLEX PROTEIN DEPDC5 cellular response to stimulus#GO:0051716;response to starvation#GO:0042594;regulation of cell communication#GO:0010646;negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;positive regulation of cellular process#GO:0048522;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;cellular response to nutrient levels#GO:0031669;regulation of response to stimulus#GO:0048583;cellular response to starvation#GO:0009267;negative regulation of cellular process#GO:0048523;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894;positive regulation of catabolic process#GO:0009896;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of autophagy#GO:0010506;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;positive regulation of metabolic process#GO:0009893;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of autophagy#GO:0010508;response to stress#GO:0006950;negative regulation of signal transduction#GO:0009968;cellular response to amino acid starvation#GO:0034198;negative regulation of TORC1 signaling#GO:1904262 protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;Seh1-associated complex#GO:0035859;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC121836685|UniProtKB=A0ACM8FZP5 A0ACM8FZP5 LOC121836685 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8052963|UniProtKB=A0ACM8E3L5 A0ACM8E3L5 LOC8052963 PTHR23235:SF197 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8043998|UniProtKB=A0ACM8FTM9 A0ACM8FTM9 p120ctn PTHR10372:SF27 PLAKOPHILLIN-RELATED P120 CATENIN protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;nucleus#GO:0005634;membrane#GO:0016020;cell-cell junction#GO:0005911 cytoskeletal protein#PC00085;intermediate filament#PC00129;intermediate filament binding protein#PC00130 IXOSC|EnsemblGenome=LOC8033825|UniProtKB=A0ACM8FR01 A0ACM8FR01 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8036184|UniProtKB=A0ACM8DJY7 A0ACM8DJY7 Yif1 PTHR14083:SF0 YIP1 INTERACTING FACTOR HOMOLOG YIF1 PROTEIN YIP1-INTERACTING FACTOR 1, ISOFORM C vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 endoplasmic reticulum membrane#GO:0005789;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;endomembrane system#GO:0012505;cytoplasm#GO:0005737;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115316881|UniProtKB=A0ACM8ENW6 A0ACM8ENW6 LOC115316881 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8053556|UniProtKB=A0ACM8G1A4 A0ACM8G1A4 LOC8053556 PTHR16166:SF146 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS13 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 13A-LIKE ISOFORM X1 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013 cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;macroautophagy#GO:0016236;lipid transport#GO:0006869;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;lipid localization#GO:0010876;catabolic process#GO:0009056;cellular component organization#GO:0016043 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;outer membrane#GO:0019867;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;endomembrane system#GO:0012505;organelle outer membrane#GO:0031968;cytoplasmic vesicle membrane#GO:0030659;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8038938|UniProtKB=A0ACM8E3H3 A0ACM8E3H3 LOC8038938 PTHR46077:SF1 E3 UBIQUITIN-PROTEIN LIGASE TOPORS E3 UBIQUITIN-PROTEIN LIGASE TOPORS aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8030429|UniProtKB=A0ACM8E4H5 A0ACM8E4H5 LOC8030429 PTHR34441:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8052481|UniProtKB=A0ACM8G0Q3 A0ACM8G0Q3 LOC8052481 PTHR43550:SF3 3-KETODIHYDROSPHINGOSINE REDUCTASE 3-KETODIHYDROSPHINGOSINE REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC115312130|UniProtKB=A0ACM8F5D1 A0ACM8F5D1 LOC115312130 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839739|UniProtKB=A0ACM8ENL9 A0ACM8ENL9 LOC120839739 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030771|UniProtKB=A0ACM8DYY2 A0ACM8DYY2 Atg3 PTHR12866:SF2 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG3 ubiquitin-like protein conjugating enzyme activity#GO:0061650;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;autophagy of mitochondrion#GO:0000422;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;organelle organization#GO:0006996;glycogen catabolic process#GO:0005980;cellular component biogenesis#GO:0044085;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glycogen metabolic process#GO:0005977;polysaccharide catabolic process#GO:0000272 cytosol#GO:0005829;phagophore assembly site#GO:0000407;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121836142|UniProtKB=A0ACM8FX10 A0ACM8FX10 LOC121836142 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120843912|UniProtKB=A0ACM8EY72 A0ACM8EY72 LOC120843912 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842012|UniProtKB=A0ACM8FKA6 A0ACM8FKA6 LOC120842012 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024598|UniProtKB=A0ACM8E0B9 A0ACM8E0B9 LOC8024598 PTHR15526:SF5 MUSKELIN MUSKELIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121838375|UniProtKB=A0ACM8G7U4 A0ACM8G7U4 LOC121838375 PTHR21220:SF0 DNA-DEPENDENT METALLOPROTEASE SPRTN DNA-DEPENDENT METALLOPROTEASE SPRTN metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120850197|UniProtKB=A0ACM8F9C3 A0ACM8F9C3 Coq7 PTHR11237:SF6 COENZYME Q10 BIOSYNTHESIS PROTEIN 7 NADPH-DEPENDENT 3-DEMETHOXYUBIQUINONE 3-HYDROXYLASE, MITOCHONDRIAL monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen#GO:0016709;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491 regulation of metabolic process#GO:0019222;ketone metabolic process#GO:0042180;regulation of biological process#GO:0050789;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;regulation of cellular process#GO:0050794;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;biosynthetic process#GO:0009058;metabolic process#GO:0008152;regulation of reactive oxygen species metabolic process#GO:2000377;small molecule biosynthetic process#GO:0044283 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle membrane#GO:0031090;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;nucleus#GO:0005634;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966 IXOSC|EnsemblGenome=LOC121835209|UniProtKB=A0ACM8FRZ1 A0ACM8FRZ1 LOC121835209 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 IXOSC|EnsemblGenome=LOC8025903|UniProtKB=A0ACM8DVL4 A0ACM8DVL4 LOC8025903 PTHR11893:SF41 INNEXIN INNEXIN INX2 wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to radiation#GO:0009314;cellular process#GO:0009987;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;response to external stimulus#GO:0009605 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 gap junction#PC00105 IXOSC|EnsemblGenome=LOC8051034|UniProtKB=A0ACM8DLF5 A0ACM8DLF5 LOC8051034 PTHR11309:SF148 FRIZZLED SECRETED FRIZZLED-RELATED PROTEIN 1 binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;signaling receptor activity#GO:0038023 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;non-canonical Wnt signaling pathway#GO:0035567 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8041824|UniProtKB=A0ACM8DS34 A0ACM8DS34 Rad17 PTHR12172:SF5 CELL CYCLE CHECKPOINT PROTEIN RAD17 CELL CYCLE CHECKPOINT PROTEIN RAD17 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;intracellular signal transduction#GO:0035556;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of cell cycle G2/M phase transition#GO:1902750;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;regulation of mitotic cell cycle phase transition#GO:1901990;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;mitotic DNA replication checkpoint signaling#GO:0033314;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;site of double-strand break#GO:0035861;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;site of DNA damage#GO:0090734;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694 IXOSC|EnsemblGenome=LOC8038213|UniProtKB=A0ACM8E7R5 A0ACM8E7R5 LOC8038213 PTHR24289:SF24 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 21-HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;hormone biosynthetic process#GO:0042446;metabolic process#GO:0008152;olefinic compound metabolic process#GO:0120254;lipid metabolic process#GO:0006629;regulation of biological quality#GO:0065008 IXOSC|EnsemblGenome=LOC8033890|UniProtKB=A0ACM8E8W4 A0ACM8E8W4 LOC8033890 PTHR11851:SF229 METALLOPROTEASE MITOCHONDRIAL-PROCESSING PEPTIDASE SUBUNIT ALPHA macromolecule localization#GO:0033036;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104 endopeptidase complex#GO:1905369;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial matrix#GO:0005759;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121836400|UniProtKB=A0ACM8FYN2 A0ACM8FYN2 LOC121836400 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051304|UniProtKB=A0ACM8EGU0 A0ACM8EGU0 LOC8051304 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040111|UniProtKB=A0ACM8DKG2 A0ACM8DKG2 ND-30 PTHR10884:SF17 NADH DEHYDROGENASE UBIQUINONE IRON-SULFUR PROTEIN 3 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 3, MITOCHONDRIAL membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121047965|UniProtKB=A0ACM8FI73 A0ACM8FI73 LOC121047965 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8025997|UniProtKB=A0ACM8DQM2 A0ACM8DQM2 Gga PTHR45905:SF1 GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN GOLGI-LOCALIZED, GAMMA-ADAPTIN EAR CONTAINING, ARF BINDING PROTEIN binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;post-Golgi vesicle-mediated transport#GO:0006892;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;localization within membrane#GO:0051668;Golgi vesicle transport#GO:0048193;transport#GO:0006810;Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791 IXOSC|EnsemblGenome=LOC115327308|UniProtKB=A0ACM8E8B5 A0ACM8E8B5 LOC115327308 PTHR12101:SF1 POPEYE DOMAIN CONTAINING PROTEIN BVES small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;multicellular organismal process#GO:0032501;heart development#GO:0007507;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;striated muscle cell differentiation#GO:0051146;developmental process#GO:0032502 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;bicellular tight junction#GO:0005923;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;tight junction#GO:0070160;sarcolemma#GO:0042383;cell junction#GO:0030054;apical junction complex#GO:0043296 IXOSC|EnsemblGenome=LOC8026963|UniProtKB=A0ACM8DR24 A0ACM8DR24 LOC8026963 PTHR45636:SF49 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED SEGMENTATION PROTEIN PAIRED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8023335|UniProtKB=A0ACM8E0L1 A0ACM8E0L1 PTHR23059:SF4 CYSTEINE AND HISTIDINE-RICH PROTEIN 1 ZINC FINGER TRAF-TYPE-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8053751|UniProtKB=A0ACM8DLQ1 A0ACM8DLQ1 Ets98B PTHR11849:SF320 ETS DNA-BINDING PROTEIN D-ETS-4 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8043379|UniProtKB=A0ACM8DUW6 A0ACM8DUW6 LOC8043379 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120842484|UniProtKB=A0ACM8ETY4 A0ACM8ETY4 LOC120842484 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309553|UniProtKB=A0ACM8F0E6 A0ACM8F0E6 LOC115309553 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053537|UniProtKB=A0ACM8E3B5 A0ACM8E3B5 LOC8053537 PTHR15967:SF1 E2F-ASSOCIATED PHOSPHOPROTEIN E2F-ASSOCIATED PHOSPHOPROTEIN transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription#GO:0006355;regulation of cell population proliferation#GO:0042127;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8031521|UniProtKB=A0ACM8FI08 A0ACM8FI08 LOC8031521 PTHR11538:SF26 PHENYLALANYL-TRNA SYNTHETASE FERREDOXIN-FOLD ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;ligase activity#GO:0016874;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101 ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA metabolic process#GO:0016070;methylation#GO:0032259;rRNA modification#GO:0000154;protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;rRNA methylation#GO:0031167;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;rRNA base methylation#GO:0070475;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;RNA processing#GO:0006396;translation#GO:0006412;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;protein metabolic process#GO:0019538;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC120845337|UniProtKB=A0ACM8F0E2 A0ACM8F0E2 LOC120845337 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115314214|UniProtKB=A0ACM8DTK8 A0ACM8DTK8 LOC115314214 PTHR31573:SF1 ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 2 DNA OXIDATIVE DEMETHYLASE ALKBH2 metal ion binding#GO:0046872;binding#GO:0005488;catalytic activity, acting on DNA#GO:0140097;iron ion binding#GO:0005506;demethylase activity#GO:0032451;ferrous iron binding#GO:0008198;cation binding#GO:0043169;dioxygenase activity#GO:0051213;hydrolase activity#GO:0016787;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152 oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8024473|UniProtKB=A0ACM8FUD5 A0ACM8FUD5 Sara PTHR46319:SF3 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;early endosome membrane#GO:0031901;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 MYO signaling pathway#P06215>SARA#P06313;Activin beta signaling pathway#P06210>SARA#P06235;ALP23B signaling pathway#P06209>SARA#P06222;TGF-beta signaling pathway#P00052>SARA#P01281 IXOSC|EnsemblGenome=LOC115327268|UniProtKB=A0ACM8FCY9 A0ACM8FCY9 nero PTHR12697:SF42 PBS LYASE HEAT-LIKE PROTEIN DEOXYHYPUSINE HYDROXYLASE oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 lyase#PC00144 IXOSC|EnsemblGenome=LOC121836106|UniProtKB=A0ACM8FWR0 A0ACM8FWR0 LOC121836106 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 transferase#PC00220 IXOSC|EnsemblGenome=LOC8025387|UniProtKB=A0ACM8EBN4 A0ACM8EBN4 Rgl PTHR23113:SF312 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAL GUANINE NUCLEOTIDE DISSOCIATION STIMULATOR-LIKE, ISOFORM E enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8026023|UniProtKB=A0ACM8ESE2 A0ACM8ESE2 mei-9 PTHR10150:SF0 DNA REPAIR ENDONUCLEASE XPF DNA REPAIR ENDONUCLEASE XPF DNA binding#GO:0003677;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;damaged DNA binding#GO:0003684 cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;mitotic recombination#GO:0006312;recombinational repair#GO:0000725;reproductive process#GO:0022414;homologous recombination#GO:0035825;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;resolution of meiotic recombination intermediates#GO:0000712 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC115329035|UniProtKB=A0ACM8F7P6 A0ACM8F7P6 LOC115329035 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120847761|UniProtKB=A0ACM8G433 A0ACM8G433 LOC120847761 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837195|UniProtKB=A0ACM8EGF1 A0ACM8EGF1 LOC120837195 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8023757|UniProtKB=A0ACM8EX34 A0ACM8EX34 LOC8023757 PTHR24082:SF511 NUCLEAR HORMONE RECEPTOR PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR DELTA sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;positive regulation of transcription by RNA polymerase II#GO:0045944 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 IXOSC|EnsemblGenome=LOC8035584|UniProtKB=A0ACM8DNQ5 A0ACM8DNQ5 LOC8035584 PTHR24273:SF32 FI04643P-RELATED SUSHI, VON WILLEBRAND FACTOR TYPE A, EGF AND PENTRAXIN DOMAIN-CONTAINING PROTEIN 1-LIKE IXOSC|EnsemblGenome=LOC115314463|UniProtKB=A0ACM8FC06 A0ACM8FC06 LOC115314463 PTHR23147:SF75 SERINE/ARGININE RICH SPLICING FACTOR RNA-BINDING PROTEIN 1-RELATED nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear speck#GO:0016607;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8026128|UniProtKB=A0ACM8E1F7 A0ACM8E1F7 LOC8026128 PTHR12436:SF4 80 KDA MCM3-ASSOCIATED PROTEIN LEUKOCYTE RECEPTOR CLUSTER MEMBER 8 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8031453|UniProtKB=A0ACM8DI98 A0ACM8DI98 PTHR47174:SF3 BRIDGING INTEGRATOR 3 BRIDGING INTEGRATOR 3 binding#GO:0005488;lipid binding#GO:0008289 cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;endocytosis#GO:0006897;cellular process#GO:0009987;cellular component organization#GO:0016043 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC120844375|UniProtKB=A0ACM8EYL8 A0ACM8EYL8 LOC120844375 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8027169|UniProtKB=A0ACM8DRJ5 A0ACM8DRJ5 LOC8027169 PTHR11177:SF317 CHITINASE GH18 DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8039093|UniProtKB=A0ACM8DTG9 A0ACM8DTG9 LOC8039093 PTHR11670:SF75 ACONITASE/IRON-RESPONSIVE ELEMENT FAMILY MEMBER CYTOPLASMIC ACONITATE HYDRATASE RNA binding#GO:0003723;lyase activity#GO:0016829;iron-sulfur cluster binding#GO:0051536;nucleic acid binding#GO:0003676;binding#GO:0005488;small molecule binding#GO:0036094;mRNA binding#GO:0003729;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 inorganic ion homeostasis#GO:0098771;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 RNA metabolism protein#PC00031 Methylcitrate cycle#P02754>Aconitase#P03028 IXOSC|EnsemblGenome=LOC115319492|UniProtKB=A0ACM8EQF4 A0ACM8EQF4 LOC115319492 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8033673|UniProtKB=A0ACM8DI64 A0ACM8DI64 LOC8033673 PTHR14359:SF6 HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY PHOSPHOPANTOTHENOYLCYSTEINE DECARBOXYLASE lyase activity#GO:0016829;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;carbon-carbon lyase activity#GO:0016830;ribonucleotide binding#GO:0032553;carboxy-lyase activity#GO:0016831;carbohydrate derivative binding#GO:0097367;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Coenzyme A biosynthesis#P02736>Pantothenoylcysteine decarboxylase#P02883;Coenzyme A biosynthesis#P02736>Pantothenate cysteine ligase#P02882 IXOSC|EnsemblGenome=LOC8030405|UniProtKB=A0ACM8FAT7 A0ACM8FAT7 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8034774|UniProtKB=A0ACM8DYM9 A0ACM8DYM9 Sra-1 PTHR12195:SF6 CYTOPLASMIC FMR1-INTERACTING PROTEIN-RELATED CYTOPLASMIC FMR1-INTERACTING PROTEIN cellular process#GO:0009987;cell projection assembly#GO:0030031;regulation of protein metabolic process#GO:0051246;cellular component biogenesis#GO:0044085;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cellular component assembly#GO:0022607;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;axon guidance#GO:0007411;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;post-transcriptional regulation of gene expression#GO:0010608;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;system development#GO:0048731;anatomical structure development#GO:0048856 cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;neuron projection#GO:0043005 scaffold/adaptor protein#PC00226 Huntington disease#P00029>p53#P00797 IXOSC|EnsemblGenome=LOC115326717|UniProtKB=A0ACM8E700 A0ACM8E700 LOC115326717 PTHR11616:SF323 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT TRANSPORTER BEDRAGGLED secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;sodium ion transport#GO:0006814;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8028666|UniProtKB=A0ACM8EE52 A0ACM8EE52 LOC8028666 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8029816|UniProtKB=A0ACM8DPL4 A0ACM8DPL4 LOC8029816 PTHR19282:SF456 TETRASPANIN FI23944P1-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115315457|UniProtKB=A0ACM8G4I9 A0ACM8G4I9 LOC115311927 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115313075|UniProtKB=A0ACM8DSP7 A0ACM8DSP7 LOC115313075 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120836196|UniProtKB=A0ACM8F7X0 A0ACM8F7X0 LOC120836196 PTHR24329:SF516 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN GOOSECOID sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120846110|UniProtKB=A0ACM8F2H3 A0ACM8F2H3 LOC120846110 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115320281|UniProtKB=A0ACM8F4Y9 A0ACM8F4Y9 LOC115320281 PTHR11547:SF38 ARGININE OR CREATINE KINASE ARGININE KINASE 1-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120847416|UniProtKB=A0ACM8F4X8 A0ACM8F4X8 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024776|UniProtKB=A0ACM8EGV7 A0ACM8EGV7 LOC8024776 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8052594|UniProtKB=A0ACM8FLM3 A0ACM8FLM3 LOC8052594 PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell cycle#GO:0007049;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115330802|UniProtKB=A0ACM8F8R6 A0ACM8F8R6 LOC115330802 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121837794|UniProtKB=A0ACM8G558 A0ACM8G558 LOC121837794 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8041819|UniProtKB=A0ACM8FEM3 A0ACM8FEM3 SH3PX1 PTHR45827:SF1 SORTING NEXIN SORTING NEXIN ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;endocytosis#GO:0006897;cellular component organization#GO:0016043;cellular localization#GO:0051641;plasma membrane organization#GO:0007009;localization#GO:0051179 cell periphery#GO:0071944;vesicle#GO:0031982;membrane#GO:0016020;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121837579|UniProtKB=A0ACM8G3R1 A0ACM8G3R1 LOC121837579 PTHR31873:SF6 L-ASPARTATE DEHYDROGENASE-RELATED ASPARTATE DEHYDROGENASE DOMAIN-CONTAINING PROTEIN dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8043150|UniProtKB=A0ACM8DRV9 A0ACM8DRV9 LOC8043150 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115314678|UniProtKB=A0ACM8FAE5 A0ACM8FAE5 LOC115314678 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115330310|UniProtKB=A0ACM8EBP9 A0ACM8EBP9 LOC115330310 PTHR13469:SF8 HEXAMETHYLENE BISACETAMIDE INDUCIBLE 1 HEXIM P-TEFB COMPLEX SUBUNIT 1 nucleic acid binding#GO:0003676;binding#GO:0005488;snRNA binding#GO:0017069;enzyme regulator activity#GO:0030234;RNA binding#GO:0003723;molecular function inhibitor activity#GO:0140678;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme inhibitor activity#GO:0004857;kinase inhibitor activity#GO:0019210;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207 negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC121833156|UniProtKB=A0ACM8FJG0 A0ACM8FJG0 LOC121833156 PTHR33198:SF22 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308162|UniProtKB=A0ACM8EQH0 A0ACM8EQH0 l(3)77CDf PTHR15362:SF15 PHOSPHATIDYLINOSITOL SYNTHASE PHOSPHATIDYLSERINE SYNTHASE 1 transferase#PC00220 IXOSC|EnsemblGenome=LOC115327164|UniProtKB=A0ACM8FFB8 A0ACM8FFB8 LOC115327164 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836269|UniProtKB=A0ACM8FY40 A0ACM8FY40 LOC121836269 PTHR10484:SF0 HISTONE H4 HISTONE H4 TYPE VIII structural molecule activity#GO:0005198 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8037652|UniProtKB=A0ACM8DQE9 A0ACM8DQE9 LOC8037652 PTHR11242:SF0 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED PEPTIDYLPROLYL ISOMERASE metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8037097|UniProtKB=A0ACM8DHX2 A0ACM8DHX2 LOC8037097 PTHR46600:SF1 THAP DOMAIN-CONTAINING THAP-TYPE DOMAIN-CONTAINING PROTEIN zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120850759|UniProtKB=A0ACM8FKU3 A0ACM8FKU3 LOC120850759 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8041307|UniProtKB=A0ACM8F5J3 A0ACM8F5J3 LOC8041307 PTHR23080:SF63 THAP DOMAIN PROTEIN DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849853|UniProtKB=A0ACM8F9F9 A0ACM8F9F9 LOC120849853 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121838015|UniProtKB=A0ACM8G679 A0ACM8G679 LOC121838015 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839308|UniProtKB=A0ACM8EMQ9 A0ACM8EMQ9 LOC120839308 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC121833138|UniProtKB=A0ACM8FKJ5 A0ACM8FKJ5 LOC121833138 PTHR12231:SF283 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8027396|UniProtKB=A0ACM8FYB9 A0ACM8FYB9 LOC8027396 PTHR13778:SF47 GLYCOSYLTRANSFERASE 8 DOMAIN-CONTAINING PROTEIN HEXOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8036972|UniProtKB=A0ACM8DWR3 A0ACM8DWR3 LOC8036972 PTHR15711:SF71 RAP GTPASE-ACTIVATING PROTEIN RAP-GAP DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC115310682|UniProtKB=A0ACM8EU99 A0ACM8EU99 LOC115310682 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838801|UniProtKB=A0ACM8G7I6 A0ACM8G7I6 LOC120838801 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115332295|UniProtKB=A0ACM8ETH6 A0ACM8ETH6 LOC115332295 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC121835782|UniProtKB=A0ACM8FWX5 A0ACM8FWX5 LOC121835782 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8025408|UniProtKB=A0ACM8EIF1 A0ACM8EIF1 LOC8025408 PTHR23317:SF76 DEDICATOR OF CYTOKINESIS DOCK LD20667P guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8036708|UniProtKB=A0ACM8EXY1 A0ACM8EXY1 LOC8036708 PTHR10340:SF63 SPHINGOMYELIN PHOSPHODIESTERASE METALLOPHOS DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC120849132|UniProtKB=A0ACM8F680 A0ACM8F680 LOC120849132 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030653|UniProtKB=A0ACM8DHD1 A0ACM8DHD1 LOC8030653 PTHR12386:SF12 ATP SYNTHASE SUBUNIT ATP SYNTHASE F(0) COMPLEX SUBUNIT G, MITOCHONDRIAL-RELATED proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874 small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;aerobic respiration#GO:0009060;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091 transporter complex#GO:1990351;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;proton-transporting ATP synthase complex#GO:0045259;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC115310520|UniProtKB=A0ACM8F0G7 A0ACM8F0G7 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8038607|UniProtKB=A0ACM8EES6 A0ACM8EES6 LOC8038607 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121833983|UniProtKB=A0ACM8FNJ7 A0ACM8FNJ7 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8034476|UniProtKB=A0ACM8DZA9 A0ACM8DZA9 mGluR PTHR24060:SF162 METABOTROPIC GLUTAMATE RECEPTOR METABOTROPIC GLUTAMATE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;transmembrane signaling receptor activity#GO:0004888 G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725 IXOSC|EnsemblGenome=LOC8030471|UniProtKB=A0ACM8DH48 A0ACM8DH48 LOC8030471 PTHR10458:SF2 PEPTIDE DEFORMYLASE PEPTIDE DEFORMYLASE, MITOCHONDRIAL intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120843037|UniProtKB=A0ACM8EV56 A0ACM8EV56 LOC120843037 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115326144|UniProtKB=A0ACM8E5K1 A0ACM8E5K1 LOC115326144 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026017|UniProtKB=A0ACM8F285 A0ACM8F285 LOC8026017 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121832885|UniProtKB=A0ACM8G389 A0ACM8G389 LOC121832885 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115330192|UniProtKB=A0ACM8EAL7 A0ACM8EAL7 LOC115330192 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033781|UniProtKB=A0ACM8DPH3 A0ACM8DPH3 LOC8033781 PTHR11893:SF39 INNEXIN INNEXIN INX1 wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 gap junction#PC00105 IXOSC|EnsemblGenome=LOC8025069|UniProtKB=A0ACM8DQD1 A0ACM8DQD1 LOC8025069 PTHR11214:SF411 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8028203|UniProtKB=A0ACM8G3T7 A0ACM8G3T7 Karybeta3 PTHR10527:SF5 IMPORTIN BETA IMPORTIN-5 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nucleocytoplasmic transport#GO:0006913;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 transporter#PC00227 IXOSC|EnsemblGenome=LOC8052509|UniProtKB=A0ACM8DPD2 A0ACM8DPD2 LOC8052509 PTHR44196:SF1 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7B PEROXISOMAL REDUCTASE ACTIVATING PPAR-GAMMA membrane#GO:0016020;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037599|UniProtKB=A0ACM8G234 A0ACM8G234 LOC8037599 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8029363|UniProtKB=A0ACM8FYU6 A0ACM8FYU6 LOC8029363 PTHR16305:SF28 TESTICULAR SOLUBLE ADENYLYL CYCLASE GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN lyase activity#GO:0016829;molecular function regulator activity#GO:0098772;adenylate cyclase activity#GO:0004016;molecular sensor activity#GO:0140299;catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975 cellular response to stimulus#GO:0051716;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;cellular response to chemical stimulus#GO:0070887;regulation of biological quality#GO:0065008;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;monoatomic ion homeostasis#GO:0050801;biological regulation#GO:0065007;response to chemical#GO:0042221;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AC#P01082;Metabotropic glutamate receptor group III pathway#P00039>AC#P01043 IXOSC|EnsemblGenome=LOC121833955|UniProtKB=A0ACM8FNF4 A0ACM8FNF4 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323665|UniProtKB=A0ACM8E432 A0ACM8E432 LOC115323665 PTHR44269:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED IP05441P alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8031326|UniProtKB=A0ACM8DI62 A0ACM8DI62 Spase12 PTHR13202:SF0 MICROSOMAL SIGNAL PEPTIDASE 12 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 1 primary metabolic process#GO:0044238;protein targeting#GO:0006605;localization#GO:0051179;protein metabolic process#GO:0019538;establishment of protein localization#GO:0045184;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of protein localization to endoplasmic reticulum#GO:0072599;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein targeting to ER#GO:0045047;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;peptidase complex#GO:1905368;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endopeptidase complex#GO:1905369;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum subcompartment#GO:0098827 protease#PC00190;protein modifying enzyme#PC00260 Vasopressin synthesis#P04395>Signal Peptidase#P04589 IXOSC|EnsemblGenome=LOC120844755|UniProtKB=A0ACM8EZ57 A0ACM8EZ57 LOC120844755 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120846950|UniProtKB=A0ACM8F3D6 A0ACM8F3D6 LOC120846950 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312851|UniProtKB=A0ACM8EQ91 A0ACM8EQ91 LOC115312851 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8052497|UniProtKB=A0ACM8DLH8 A0ACM8DLH8 LOC8052497 PTHR23030:SF45 PCD6 INTERACTING PROTEIN-RELATED TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 23 catabolic process#GO:0009056;protein localization to organelle#GO:0033365;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;localization#GO:0051179;protein metabolic process#GO:0019538;localization within membrane#GO:0051668;protein localization to vacuole#GO:0072665;endosome transport via multivesicular body sorting pathway#GO:0032509;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;early endosome to late endosome transport#GO:0045022;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;macromolecule localization#GO:0033036;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;ubiquitin-dependent protein catabolic process#GO:0006511;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;late endosome to vacuole transport#GO:0045324;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;establishment of protein localization to vacuole#GO:0072666;endocytic recycling#GO:0032456;protein transport#GO:0015031;cellular localization#GO:0051641;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;endosomal transport#GO:0016197;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120839080|UniProtKB=A0ACM8ELZ0 A0ACM8ELZ0 LOC120839080 PTHR11006:SF125 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 3 histone modifying activity#GO:0140993;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8050586|UniProtKB=A0ACM8DS71 A0ACM8DS71 LOC8050586 PTHR47341:SF1 GATA-TYPE ZINC FINGER PROTEIN 1 GATA-TYPE ZINC FINGER PROTEIN 1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8052163|UniProtKB=A0ACM8DLG0 A0ACM8DLG0 mRpL11 PTHR11661:SF48 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11M structural molecule activity#GO:0005198;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;binding#GO:0005488;rRNA binding#GO:0019843 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120848412|UniProtKB=A0ACM8FZZ8 A0ACM8FZZ8 LOC120848412 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115328602|UniProtKB=A0ACM8F2C1 A0ACM8F2C1 LOC115328602 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8024345|UniProtKB=A0ACM8E325 A0ACM8E325 LOC8024345 PTHR11588:SF501 TUBULIN TUBULIN ALPHA CHAIN small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 tubulin#PC00228;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC121836833|UniProtKB=A0ACM8G1T7 A0ACM8G1T7 LOC121836833 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC121834291|UniProtKB=A0ACM8FQ20 A0ACM8FQ20 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115308356|UniProtKB=A0ACM8DMB8 A0ACM8DMB8 LOC115308356 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8029323|UniProtKB=A0ACM8DHZ8 A0ACM8DHZ8 ND-49 PTHR11993:SF48 NADH-UBIQUINONE OXIDOREDUCTASE 49 KDA SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 2, MITOCHONDRIAL transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;monoatomic ion transmembrane transporter activity#GO:0015075;oxidoreductase activity#GO:0016491;NADH dehydrogenase activity#GO:0003954;oxidoreductase activity, acting on NAD(P)H#GO:0016651;monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055 electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 mitochondrial inner membrane#GO:0005743;oxidoreductase complex#GO:1990204;membrane#GO:0016020;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;respiratory chain complex I#GO:0045271;transporter complex#GO:1990351;organelle membrane#GO:0031090;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115320265|UniProtKB=A0ACM8FEZ4 A0ACM8FEZ4 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325237|UniProtKB=A0ACM8G4Q2 A0ACM8G4Q2 LOC115325237 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120840232|UniProtKB=A0ACM8ENF2 A0ACM8ENF2 LOC120840232 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 organelle localization#GO:0051640;localization within membrane#GO:0051668;localization#GO:0051179;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;negative regulation of macromolecule metabolic process#GO:0010605;membrane organization#GO:0061024;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;cellular localization#GO:0051641;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC8030273|UniProtKB=A0ACM8DGJ6 A0ACM8DGJ6 LOC8030273 PTHR12760:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN ER MEMBRANE PROTEIN COMPLEX SUBUNIT 2 membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;EMC complex#GO:0072546;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120842616|UniProtKB=A0ACM8EU77 A0ACM8EU77 LOC120842616 PTHR24390:SF79 ZINC FINGER PROTEIN LD33778P transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120848126|UniProtKB=A0ACM8F588 A0ACM8F588 LOC120848126 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115328907|UniProtKB=A0ACM8F2I6 A0ACM8F2I6 LOC115328907 PTHR24264:SF91 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120836991|UniProtKB=A0ACM8EHB3 A0ACM8EHB3 LOC120836991 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847813|UniProtKB=A0ACM8F4K6 A0ACM8F4K6 LOC120847813 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120840739|UniProtKB=A0ACM8EPT4 A0ACM8EPT4 LOC120840739 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121834716|UniProtKB=A0ACM8FQS7 A0ACM8FQS7 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840901|UniProtKB=A0ACM8EQ26 A0ACM8EQ26 LOC120840901 PTHR20948:SF2 TRANSMEMBRANE PROTEIN 164 RH09039P IXOSC|EnsemblGenome=LOC120846861|UniProtKB=A0ACM8F359 A0ACM8F359 Mcm7 PTHR11630:SF26 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM7 nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853 response to stimulus#GO:0050896;DNA strand elongation involved in DNA replication#GO:0006271;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;DNA-templated DNA replication#GO:0006261;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;DNA damage response#GO:0006974;DNA recombination#GO:0006310 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;MCM complex#GO:0042555 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8028247|UniProtKB=A0ACM8FG27 A0ACM8FG27 LOC8028247 PTHR24252:SF7 ACROSIN-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-LIKE ISOFORM X1 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120846867|UniProtKB=A0ACM8FT07 A0ACM8FT07 LOC120846867 PTHR21119:SF5 C2 DOMAIN-CONTAINING PROTEIN C2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330235|UniProtKB=A0ACM8EBI2 A0ACM8EBI2 LOC115330235 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic cation transmembrane transporter activity#GO:0008324 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120847455|UniProtKB=A0ACM8FTR1 A0ACM8FTR1 LOC120847455 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC121047087|UniProtKB=A0ACM8FU01 A0ACM8FU01 LOC121047087 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120850713|UniProtKB=A0ACM8FAW5 A0ACM8FAW5 LOC120850713 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC115319847|UniProtKB=A0ACM8FBC0 A0ACM8FBC0 LOC115319847 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039799|UniProtKB=A0ACM8DKF2 A0ACM8DKF2 Taf5 PTHR19879:SF1 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123;SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transcription factor TFIID complex#GO:0005669;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transferase complex#GO:1990234;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;peptidase complex#GO:1905368;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120843560|UniProtKB=A0ACM8EWG1 A0ACM8EWG1 LOC120843560 PTHR47160:SF11 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042784|UniProtKB=A0ACM8DPJ2 A0ACM8DPJ2 LOC8042784 PTHR11138:SF5 METHIONYL-TRNA FORMYLTRANSFERASE METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8033347|UniProtKB=A0ACM8E321 A0ACM8E321 LOC8033347 PTHR45736:SF1 ZINC FINGER MYM-TYPE PROTEIN WITHOUT CHILDREN, ISOFORM B zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115325113|UniProtKB=A0ACM8EGM9 A0ACM8EGM9 LOC115325113 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8040940|UniProtKB=A0ACM8EFJ0 A0ACM8EFJ0 LOC8040940 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC120846338|UniProtKB=A0ACM8FFX4 A0ACM8FFX4 LOC120846338 PTHR11610:SF178 LIPASE FI01825P-RELATED lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 IXOSC|EnsemblGenome=LOC8031791|UniProtKB=A0ACM8DIR6 A0ACM8DIR6 LOC8031791 PTHR13026:SF0 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING 1B transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115322262|UniProtKB=A0ACM8ENM4 A0ACM8ENM4 LOC115322262 PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;catalytic complex#GO:1902494 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121837856|UniProtKB=A0ACM8G6G2 A0ACM8G6G2 LOC121837856 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC8053672|UniProtKB=A0ACM8DXI3 A0ACM8DXI3 LOC8053672 PTHR24070:SF266 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY SMALL MONOMERIC GTPASE GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;calmodulin binding#GO:0005516;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC115312911|UniProtKB=A0ACM8FAI9 A0ACM8FAI9 LOC115312911 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843523|UniProtKB=A0ACM8EWD7 A0ACM8EWD7 LOC120843523 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC8051486|UniProtKB=A0ACM8DLF0 A0ACM8DLF0 LOC8051486 PTHR22749:SF14 RIBOFLAVIN KINASE/FMN ADENYLYLTRANSFERASE RIBOFLAVIN KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;flavin-containing compound metabolic process#GO:0042726;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;ribose phosphate biosynthetic process#GO:0046390;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 Flavin biosynthesis#P02741>FAD synthetase#P02936;Flavin biosynthesis#P02741>Riboflavin kinase#P02934 IXOSC|EnsemblGenome=LOC120836169|UniProtKB=A0ACM8ER77 A0ACM8ER77 LOC120836169 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316941|UniProtKB=A0ACM8F9U8 A0ACM8F9U8 LOC115316941 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8044019|UniProtKB=A0ACM8EDA2 A0ACM8EDA2 LOC8044019 PTHR15245:SF20 SYMPLEKIN-RELATED SYMPLEKIN nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8024487|UniProtKB=A0ACM8E9W4 A0ACM8E9W4 Rtc1 PTHR11096:SF1 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN cyclase activity#GO:0009975;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8031786|UniProtKB=A0ACM8DIR7 A0ACM8DIR7 LOC8031786 PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120840887|UniProtKB=A0ACM8EQP8 A0ACM8EQP8 LOC120840887 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841754|UniProtKB=A0ACM8G5N1 A0ACM8G5N1 LOC120841754 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121838446|UniProtKB=A0ACM8G8Y2 A0ACM8G8Y2 LOC121838446 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8053682|UniProtKB=A0ACM8F6C7 A0ACM8F6C7 PTHR11034:SF40 N-MYC DOWNSTREAM REGULATED BCDNA.GH02439 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120837978|UniProtKB=A0ACM8EJH6 A0ACM8EJH6 LOC120837978 PTHR12496:SF0 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8037558|UniProtKB=A0ACM8DTG7 A0ACM8DTG7 Nedd4 PTHR11254:SF447 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE NEDD-4 ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;transporter regulator activity#GO:0141108;ubiquitin protein ligase activity#GO:0061630;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 regulation of cellular process#GO:0050794;regulation of dendrite development#GO:0050773;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of developmental process#GO:0050793;primary metabolic process#GO:0044238;regulation of dendrite morphogenesis#GO:0048814;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of neuron projection development#GO:0010975;regulation of anatomical structure morphogenesis#GO:0022603;macromolecule metabolic process#GO:0043170;regulation of plasma membrane bounded cell projection organization#GO:0120035;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;regulation of cell projection organization#GO:0031344;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115315222|UniProtKB=A0ACM8G5Y6 A0ACM8G5Y6 LOC115315222 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120841998|UniProtKB=A0ACM8ESX5 A0ACM8ESX5 PTHR46289:SF24 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE IXOSC|EnsemblGenome=LOC8043108|UniProtKB=A0ACM8EEB1 A0ACM8EEB1 LOC8043108 PTHR16238:SF7 GEM-ASSOCIATED PROTEIN 8 GEM-ASSOCIATED PROTEIN 8 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613 Sm-like protein family complex#GO:0120114;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;SMN complex#GO:0032797 IXOSC|EnsemblGenome=LOC8029109|UniProtKB=A0ACM8FB64 A0ACM8FB64 LOC8029109 PTHR13831:SF0 MEMBER OF THE HIR1 FAMILY OF WD-REPEAT PROTEINS PROTEIN HIRA chromatin binding#GO:0003682;binding#GO:0005488;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8037352|UniProtKB=A0ACM8E8C2 A0ACM8E8C2 LOC8037352 PTHR10794:SF98 ABHYDROLASE DOMAIN-CONTAINING PROTEIN ALPHA_BETA HYDROLASE 1, ISOFORM A catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;monocarboxylic acid catabolic process#GO:0072329;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8043638|UniProtKB=A0ACM8DGS3 A0ACM8DGS3 PTHR12307:SF36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT protein phosphatase binding#GO:0019903;carbohydrate binding#GO:0030246;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of polysaccharide metabolic process#GO:0032881;regulation of carbohydrate biosynthetic process#GO:0043255;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC8025519|UniProtKB=A0ACM8DJ99 A0ACM8DJ99 LOC8025519 PTHR12499:SF30 OPTIC ATROPHY 3 PROTEIN OPA3 OPTIC ATROPHY 3 PROTEIN system process#GO:0003008;multicellular organismal process#GO:0032501;neuromuscular process#GO:0050905;nervous system process#GO:0050877 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8034341|UniProtKB=A0ACM8DMH7 A0ACM8DMH7 LOC8034341 PTHR24068:SF565 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8051185|UniProtKB=A0ACM8DLW2 A0ACM8DLW2 IntS1 PTHR21224:SF1 INTEGRATOR COMPLEX SUBUNIT 1 INTEGRATOR COMPLEX SUBUNIT 1 snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;integrator complex#GO:0032039 IXOSC|EnsemblGenome=LOC120835939|UniProtKB=A0ACM8E9V9 A0ACM8E9V9 LOC120835939 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 IXOSC|EnsemblGenome=LOC120836657|UniProtKB=A0ACM8EGG9 A0ACM8EGG9 LOC120836657 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328057|UniProtKB=A0ACM8E888 A0ACM8E888 LOC115328057 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120847343|UniProtKB=A0ACM8F308 A0ACM8F308 LOC120847343 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316311|UniProtKB=A0ACM8ER46 A0ACM8ER46 LOC115316311 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC121838163|UniProtKB=A0ACM8G6M7 A0ACM8G6M7 LOC121838163 PTHR24247:SF241 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2A-RELATED neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007 dendritic tree#GO:0097447;dendrite#GO:0030425;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 IXOSC|EnsemblGenome=LOC120847910|UniProtKB=A0ACM8F4Y6 A0ACM8F4Y6 LOC120847910 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115313186|UniProtKB=A0ACM8F1T2 A0ACM8F1T2 LOC115313186 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040094|UniProtKB=A0ACM8E819 A0ACM8E819 Fsn PTHR12245:SF7 SPRY DOMAIN CONTAINING SOCS BOX PROTEIN F-BOX_SPRY DOMAIN-CONTAINING PROTEIN 1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 animal gross anatomical part developmental process#GO:0160108;synapse organization#GO:0050808;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;anatomical structure development#GO:0048856;protein metabolic process#GO:0019538;system development#GO:0048731;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;synapse assembly#GO:0007416;cell junction organization#GO:0034330;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;proteasomal protein catabolic process#GO:0010498 cellular anatomical structure#GO:0110165;synapse#GO:0045202;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;cell junction#GO:0030054;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8029649|UniProtKB=A0ACM8EE67 A0ACM8EE67 LOC8029649 PTHR11552:SF233 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI02019P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8036898|UniProtKB=A0ACM8ESA2 A0ACM8ESA2 PTHR11205:SF18 RIBOSOMAL PROTEIN S7 SMALL RIBOSOMAL SUBUNIT PROTEIN US7 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8026222|UniProtKB=A0ACM8DHE1 A0ACM8DHE1 LOC8026222 PTHR12652:SF50 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXIN 11 cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;organelle organization#GO:0006996;cellular component organization#GO:0016043;peroxisome organization#GO:0007031;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778 IXOSC|EnsemblGenome=LOC115311830|UniProtKB=A0ACM8EFX7 A0ACM8EFX7 Alr PTHR12645:SF0 ALR/ERV SULFHYDRYL OXIDASE catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;nucleotide binding#GO:0000166;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;binding#GO:0005488;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;protein-disulfide reductase activity#GO:0015035 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC115312040|UniProtKB=A0ACM8DRT4 A0ACM8DRT4 LOC115312040 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation transmembrane transporter activity#GO:0008324;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023 metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC120844593|UniProtKB=A0ACM8EZ60 A0ACM8EZ60 LOC120844593 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC120840826|UniProtKB=A0ACM8EQ56 A0ACM8EQ56 LOC120840826 PTHR24208:SF168 LIM/HOMEOBOX PROTEIN LHX PROTEIN APTEROUS sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121046962|UniProtKB=A0ACM8FDY6 A0ACM8FDY6 LOC121046962 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121835620|UniProtKB=A0ACM8FUG5 A0ACM8FUG5 LOC121835620 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8033079|UniProtKB=A0ACM8DU58 A0ACM8DU58 LOC8033079 PTHR23282:SF152 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039017|UniProtKB=A0ACM8EEG5 A0ACM8EEG5 LOC8039017 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8030150|UniProtKB=A0ACM8G394 A0ACM8G394 LOC8030150 PTHR45702:SF2 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protein modifying enzyme#PC00260;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 IXOSC|EnsemblGenome=LOC8024561|UniProtKB=A0ACM8DZC8 A0ACM8DZC8 LOC8024561 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115314479|UniProtKB=A0ACM8EPC9 A0ACM8EPC9 LOC115314479 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC115315007|UniProtKB=A0ACM8EHC4 A0ACM8EHC4 LOC115315007 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8051282|UniProtKB=A0ACM8EAI0 A0ACM8EAI0 Xpc PTHR12135:SF3 DNA REPAIR PROTEIN XP-C / RAD4 DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;mismatch repair#GO:0006298 intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 IXOSC|EnsemblGenome=LOC121047422|UniProtKB=A0ACM8FFY9 A0ACM8FFY9 LOC121047422 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC8024609|UniProtKB=A0ACM8E0W2 A0ACM8E0W2 LOC8024609 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8036279|UniProtKB=A0ACM8DRY7 A0ACM8DRY7 LOC8036279 PTHR13090:SF1 ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL ARGININE-HYDROXYLASE NDUFAF5, MITOCHONDRIAL protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC115316347|UniProtKB=A0ACM8EUZ2 A0ACM8EUZ2 LOC115316347 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120840307|UniProtKB=A0ACM8EN58 A0ACM8EN58 LOC120840307 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115311052|UniProtKB=A0ACM8DQM6 A0ACM8DQM6 LOC115311053 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051948|UniProtKB=A0ACM8DW88 A0ACM8DW88 LOC8051948 PTHR13066:SF2 BASIC LEUCINE ZIPPER NUCLEAR FACTOR 1 BLZF1 PROTEIN GOLGIN-45 intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;Golgi vesicle transport#GO:0048193;protein localization to cell periphery#GO:1990778;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;Golgi organization#GO:0007030;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8038490|UniProtKB=A0ACM8ENC5 A0ACM8ENC5 LOC8038490 PTHR47385:SF27 CALPONIN MUSCLE-SPECIFIC PROTEIN 20 binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8025663|UniProtKB=A0ACM8DJF5 A0ACM8DJF5 Arl1 PTHR11711:SF41 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 1 heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;guanyl nucleotide binding#GO:0019001 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 G-protein#PC00020 Huntington disease#P00029>ARF#P00786;Integrin signalling pathway#P00034>Arf1#P00923 IXOSC|EnsemblGenome=LOC8025350|UniProtKB=A0ACM8DYQ9 A0ACM8DYQ9 LOC8025350 PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED dicarboxylic acid transmembrane transporter activity#GO:0005310;succinate transmembrane transporter activity#GO:0015141;C4-dicarboxylate transmembrane transporter activity#GO:0015556;citrate transmembrane transporter activity#GO:0015137;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 cellular process#GO:0009987;succinate transport#GO:0015744;dicarboxylic acid transport#GO:0006835;citrate transport#GO:0015746;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;tricarboxylic acid transport#GO:0006842;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8027032|UniProtKB=A0ACM8EWS3 A0ACM8EWS3 LOC8027032 PTHR14130:SF14 3BP-1 RELATED RHOGAP RHO GTPASE-ACTIVATING PROTEIN 92B molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of actin cytoskeleton organization#GO:0032956;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC120850521|UniProtKB=A0ACM8F8Z1 A0ACM8F8Z1 LOC120850521 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC120836930|UniProtKB=A0ACM8EG58 A0ACM8EG58 LOC120836930 PTHR33198:SF22 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312897|UniProtKB=A0ACM8G2Y8 A0ACM8G2Y8 LOC115312897 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032978|UniProtKB=A0ACM8E226 A0ACM8E226 LOC8032978 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043382|UniProtKB=A0ACM8DRP3 A0ACM8DRP3 PTHR20959:SF1 TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG transport#GO:0006810;localization#GO:0051179;protein secretion#GO:0009306;establishment of localization#GO:0051234;secretion#GO:0046903;intracellular protein localization#GO:0008104;secretion by cell#GO:0032940;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;export from cell#GO:0140352 IXOSC|EnsemblGenome=LOC115325884|UniProtKB=A0ACM8E5A7 A0ACM8E5A7 LOC115325884 PTHR22809:SF11 METHYLTRANSFERASE-RELATED TRNA N(3)-METHYLCYTIDINE METHYLTRANSFERASE METTL2 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC121835301|UniProtKB=A0ACM8FT73 A0ACM8FT73 LOC121835301 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120839522|UniProtKB=A0ACM8ELE4 A0ACM8ELE4 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115326411|UniProtKB=A0ACM8ESF4 A0ACM8ESF4 LOC115326411 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8029760|UniProtKB=A0ACM8EWA7 A0ACM8EWA7 LOC8029760 PTHR10590:SF24 SODIUM/NUCLEOSIDE COTRANSPORTER CONCENTRATIVE NUCLEOSIDE TRANSPORTER 1-RELATED secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;nucleoside transmembrane transporter activity#GO:0005337;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120850020|UniProtKB=A0ACM8F990 A0ACM8F990 LOC120850020 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319072|UniProtKB=A0ACM8DZJ1 A0ACM8DZJ1 MICU3 PTHR12294:SF13 EF HAND DOMAIN FAMILY A1,A2-RELATED MITOCHONDRIAL CALCIUM UPTAKE 3, ISOFORM D calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;monoatomic ion channel complex#GO:0034702;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;transporter complex#GO:1990351;organelle membrane#GO:0031090;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800 calmodulin-related#PC00061;calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC8032858|UniProtKB=A0ACM8DH49 A0ACM8DH49 LOC8032858 PTHR46600:SF1 THAP DOMAIN-CONTAINING THAP-TYPE DOMAIN-CONTAINING PROTEIN gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8053837|UniProtKB=A0ACM8EUA8 A0ACM8EUA8 LOC8053837 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121838040|UniProtKB=A0ACM8G6B3 A0ACM8G6B3 LOC121838040 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115311615|UniProtKB=A0ACM8DR10 A0ACM8DR10 LOC115311615 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115310447|UniProtKB=A0ACM8EGH0 A0ACM8EGH0 LOC115310447 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839670|UniProtKB=A0ACM8END6 A0ACM8END6 LOC120839670 PTHR24072:SF411 RHO FAMILY GTPASE RAS-RELATED PROTEIN RAC1-RELATED nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;protein binding#GO:0005515;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899 signaling#GO:0023052;cell differentiation#GO:0030154;cell projection organization#GO:0030030;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;Rac protein signal transduction#GO:0016601;generation of neurons#GO:0048699;establishment or maintenance of cell polarity#GO:0007163;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;regulation of developmental process#GO:0050793;regulation of cytoskeleton organization#GO:0051493;actin cytoskeleton organization#GO:0030036;supramolecular fiber organization#GO:0097435;system development#GO:0048731;intracellular signal transduction#GO:0035556;regulation of cell motility#GO:2000145;cell communication#GO:0007154;cortical cytoskeleton organization#GO:0030865;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;cell development#GO:0048468;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell shape#GO:0008360;regulation of biological quality#GO:0065008;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;intracellular signaling cassette#GO:0141124;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;anatomical structure development#GO:0048856;actin filament-based process#GO:0030029;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;actin filament organization#GO:0007015;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 small GTPase#PC00208;G-protein#PC00020 Cytoskeletal regulation by Rho GTPase#P00016>Rac#P00523;Axon guidance mediated by netrin#P00009>Rac#P00366;Axon guidance mediated by Slit/Robo#P00008>Rac#P00354;Integrin signalling pathway#P00034>Rac#P00927;Huntington disease#P00029>Rac#P00775;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Cdc42#P00834;Ras Pathway#P04393>Rac#P04559;T cell activation#P00053>rac#P01324;EGF receptor signaling pathway#P00018>Rac#P00564;FGF signaling pathway#P00021>Rac#P00645 IXOSC|EnsemblGenome=LOC120838707|UniProtKB=A0ACM8EJQ9 A0ACM8EJQ9 LOC120838707 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313117|UniProtKB=A0ACM8FSW6 A0ACM8FSW6 LOC115313117 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8025551|UniProtKB=A0ACM8DW62 A0ACM8DW62 LOC8025551 PTHR46809:SF2 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN GH21273P IXOSC|EnsemblGenome=LOC8042452|UniProtKB=A0ACM8DKX2 A0ACM8DKX2 LOC8042452 PTHR46600:SF1 THAP DOMAIN-CONTAINING THAP-TYPE DOMAIN-CONTAINING PROTEIN zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8030557|UniProtKB=A0ACM8E4J9 A0ACM8E4J9 LOC8030557 PTHR31101:SF2 UPF0547 PROTEIN C16ORF87 C16ORF87 HOMOLOG IXOSC|EnsemblGenome=LOC8033422|UniProtKB=A0ACM8ETS4 A0ACM8ETS4 Tpc1 PTHR24089:SF59 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL THIAMINE PYROPHOSPHATE CARRIER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;quaternary ammonium group transmembrane transporter activity#GO:0015651;organophosphate ester transmembrane transporter activity#GO:0015605 quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;organophosphate ester transport#GO:0015748;vitamin transport#GO:0051180;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120839152|UniProtKB=A0ACM8EMF8 A0ACM8EMF8 LOC120839152 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040220|UniProtKB=A0ACM8DKJ3 A0ACM8DKJ3 LOC8040220 PTHR45787:SF1 LD11652P BEADEX, ISOFORM D transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120842240|UniProtKB=A0ACM8ETB6 A0ACM8ETB6 LOC120842240 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042805|UniProtKB=A0ACM8DU25 A0ACM8DU25 PolZ2 PTHR11842:SF10 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2B response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;DNA polymerase complex#GO:0042575;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120839941|UniProtKB=A0ACM8EMV5 A0ACM8EMV5 LOC120839941 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053161|UniProtKB=A0ACM8DM36 A0ACM8DM36 RpLP1 PTHR45696:SF10 60S ACIDIC RIBOSOMAL PROTEIN P1 LARGE RIBOSOMAL SUBUNIT PROTEIN P1 protein kinase activator activity#GO:0030295;structural constituent of ribosome#GO:0003735;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;structural molecule activity#GO:0005198;binding#GO:0005488;kinase activator activity#GO:0019209;protein-containing complex binding#GO:0044877;molecular function activator activity#GO:0140677;ribonucleoprotein complex binding#GO:0043021;enzyme regulator activity#GO:0030234 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8033560|UniProtKB=A0ACM8FCF6 A0ACM8FCF6 LOC8033560 PTHR46958:SF3 B-CELL RECEPTOR CD22 HEMICENTIN 2 IXOSC|EnsemblGenome=LOC120849733|UniProtKB=A0ACM8F8L5 A0ACM8F8L5 LOC120849733 PTHR45913:SF5 EPM2A-INTERACTING PROTEIN 1 HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025291|UniProtKB=A0ACM8E225 A0ACM8E225 P58IPK PTHR44140:SF2 LD25575P LD25575P protein-folding chaperone binding#GO:0051087;binding#GO:0005488;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121836589|UniProtKB=A0ACM8FZB4 A0ACM8FZB4 LOC121836589 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115331261|UniProtKB=A0ACM8EPX7 A0ACM8EPX7 LOC115331261 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121832868|UniProtKB=A0ACM8G608 A0ACM8G608 LOC121832868 PTHR14611:SF7 TECTONIC FAMILY MEMBER TECTONIC plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;ciliary transition zone#GO:0035869 IXOSC|EnsemblGenome=LOC120840854|UniProtKB=A0ACM8EQF0 A0ACM8EQF0 LOC120840854 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121837560|UniProtKB=A0ACM8G4Y8 A0ACM8G4Y8 LOC121837560 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121045872|UniProtKB=A0ACM8FDC9 A0ACM8FDC9 PTHR24198:SF196 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ZU5 DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8028941|UniProtKB=A0ACM8FF86 A0ACM8FF86 LOC8028941 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115322038|UniProtKB=A0ACM8E1M6 A0ACM8E1M6 Prosbeta5 PTHR11599:SF246 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT BETA peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494 protease#PC00190;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC8032955|UniProtKB=A0ACM8DH90 A0ACM8DH90 LOC8032955 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 transport#GO:0006810;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;establishment of localization#GO:0051234;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;ceramide metabolic process#GO:0006672;localization#GO:0051179;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;carbohydrate derivative catabolic process#GO:1901136;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115318729|UniProtKB=A0ACM8F878 A0ACM8F878 LOC115318729 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8023698|UniProtKB=A0ACM8E3I1 A0ACM8E3I1 Nadk2 PTHR13158:SF5 FAMILY NOT NAMED NAD KINASE 2, MITOCHONDRIAL kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117;nucleobase-containing small molecule metabolic process#GO:0055086 IXOSC|EnsemblGenome=LOC8024657|UniProtKB=A0ACM8EDD8 A0ACM8EDD8 NaPi-III PTHR11101:SF97 PHOSPHATE TRANSPORTER PHOSPHATE TRANSPORTER phosphate transmembrane transporter activity#GO:0005315;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC121836491|UniProtKB=A0ACM8G065 A0ACM8G065 LOC121836491 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8042881|UniProtKB=A0ACM8DXA7 A0ACM8DXA7 LOC8042881 PTHR21222:SF2 MIT DOMAIN-CONTAINING PROTEIN 1 FI11682P-RELATED IXOSC|EnsemblGenome=LOC120840946|UniProtKB=A0ACM8EQW5 A0ACM8EQW5 LOC120840946 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316817|UniProtKB=A0ACM8EKQ6 A0ACM8EKQ6 LOC115316817 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037166|UniProtKB=A0ACM8DMY4 A0ACM8DMY4 blp PTHR12388:SF0 MITOCHONDRIA ASSOCIATED GRANULOCYTE MACROPHAGE CSF SIGNALING MOLECULE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM16 mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;mitochondrial transmembrane transport#GO:1990542;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular transport#GO:0046907 organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle lumen#GO:0043233;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 IXOSC|EnsemblGenome=LOC121836329|UniProtKB=A0ACM8FXT7 A0ACM8FXT7 LOC121836329 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN circulatory system development#GO:0072359;heart development#GO:0007507;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;system development#GO:0048731;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 IXOSC|EnsemblGenome=LOC115332062|UniProtKB=A0ACM8EN26 A0ACM8EN26 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038015|UniProtKB=A0ACM8DIE5 A0ACM8DIE5 mRpS33 PTHR13362:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S33 SMALL RIBOSOMAL SUBUNIT PROTEIN MS33 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC115324025|UniProtKB=A0ACM8FK08 A0ACM8FK08 LOC115324025 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8033642|UniProtKB=A0ACM8G3L1 A0ACM8G3L1 LOC8033642 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115332464|UniProtKB=A0ACM8F5C7 A0ACM8F5C7 LOC120845780 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036169|UniProtKB=A0ACM8ENJ9 A0ACM8ENJ9 LOC8036169 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115315943|UniProtKB=A0ACM8DVY5 A0ACM8DVY5 LOC115315943 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832857|UniProtKB=B7P6M2 B7P6M2 PTHR24235:SF29 NEUROPEPTIDE Y RECEPTOR GH23382P peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115328187|UniProtKB=A0ACM8E8G5 A0ACM8E8G5 LOC115328187 PTHR24256:SF579 TRYPTASE-RELATED WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115320719|UniProtKB=A0ACM8FUJ1 A0ACM8FUJ1 LOC115320719 PTHR46396:SF1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetylglucosaminyltransferase activity#GO:0008375;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8029338|UniProtKB=A0ACM8DYX5 A0ACM8DYX5 dre4 PTHR13980:SF15 CDC68 RELATED FACT COMPLEX SUBUNIT SPT16 protein carrier activity#GO:0140597;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;molecular carrier activity#GO:0140104;binding#GO:0005488;chromatin binding#GO:0003682 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115313039|UniProtKB=A0ACM8F1V5 A0ACM8F1V5 LOC115313039 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045537|UniProtKB=A0ACM8FP85 A0ACM8FP85 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027197|UniProtKB=A0ACM8E7M0 A0ACM8E7M0 GAA1 PTHR13304:SF0 GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN GPI-ANCHOR TRANSAMIDASE COMPONENT GPAA1 gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchored protein biosynthesis#GO:0180046;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;endopeptidase complex#GO:1905369;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;caspase complex#GO:0008303;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120846333|UniProtKB=A0ACM8F1U8 A0ACM8F1U8 LOC120846333 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836182|UniProtKB=A0ACM8EJD0 A0ACM8EJD0 LOC120836182 PTHR46421:SF1 PROGRAMMED CELL DEATH PROTEIN 2-LIKE US5 ASSEMBLY CHAPERONE PDCD2L cell death#GO:0008219;apoptotic process#GO:0006915;cellular process#GO:0009987;programmed cell death#GO:0012501 IXOSC|EnsemblGenome=LOC115315909|UniProtKB=A0ACM8F847 A0ACM8F847 LOC115315909 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8024385|UniProtKB=A0ACM8FB45 A0ACM8FB45 Sec24AB PTHR13803:SF39 SEC24-RELATED PROTEIN SECRETORY 24AB, ISOFORM A zinc ion binding#GO:0008270;SNARE binding#GO:0000149;metal ion binding#GO:0046872;protein binding#GO:0005515;cation binding#GO:0043169;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;transition metal ion binding#GO:0046914 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;COPII-coated vesicle budding#GO:0090114;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043 protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;transport vesicle#GO:0030133;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC115327981|UniProtKB=A0ACM8FAK1 A0ACM8FAK1 LOC115327981 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322196|UniProtKB=A0ACM8EG83 A0ACM8EG83 LOC115322196 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121834524|UniProtKB=A0ACM8FNX4 A0ACM8FNX4 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120840713|UniProtKB=A0ACM8EPW9 A0ACM8EPW9 LOC120840713 PTHR11073:SF1 CALRETICULIN AND CALNEXIN CALNEXIN 14D-RELATED calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;response to chemical#GO:0042221;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein folding#GO:0006457;response to stimulus#GO:0050896;catabolic process#GO:0009056;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121046379|UniProtKB=A0ACM8FCM6 A0ACM8FCM6 LOC121046379 PTHR24346:SF112 MAP/MICROTUBULE AFFINITY-REGULATING KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;microtubule cytoskeleton organization#GO:0000226;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;signal transduction#GO:0007165;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121048543|UniProtKB=A0ACM8FHB5 A0ACM8FHB5 LOC121048543 PTHR24043:SF13 SCAVENGER RECEPTOR CLASS F EGF-LIKE DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115324171|UniProtKB=A0ACM8EN11 A0ACM8EN11 LOC115324171 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833153|UniProtKB=A0ACM8FIE5 A0ACM8FIE5 LOC121833153 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8051218|UniProtKB=A0ACM8FIT3 A0ACM8FIT3 LOC8051218 PTHR44216:SF3 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 PROTEIN O-MANNOSYL-TRANSFERASE TMTC2 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115324200|UniProtKB=A0ACM8E4L1 A0ACM8E4L1 LOC115324200 PTHR12246:SF26 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121835246|UniProtKB=A0ACM8FS39 A0ACM8FS39 LOC121835246 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030094|UniProtKB=A0ACM8FD37 A0ACM8FD37 LOC8030094 PTHR46726:SF1 TWO PORE CHANNEL 3 TWO-PORE CALCIUM CHANNEL 3 channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;voltage-gated sodium channel activity#GO:0005248;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;passive transmembrane transporter activity#GO:0022803 action potential#GO:0001508;regulation of membrane potential#GO:0042391;biological regulation#GO:0065007;regulation of biological quality#GO:0065008 ion channel#PC00133 IXOSC|EnsemblGenome=LOC115322083|UniProtKB=A0ACM8E2I1 A0ACM8E2I1 LOC115322083 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032975|UniProtKB=A0ACM8FJH4 A0ACM8FJH4 LOC8032975 PTHR11359:SF0 AMP DEAMINASE AMP DEAMINASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390 deaminase#PC00088 Purine metabolism#P02769>5'-AMP Deaminase#P03117 IXOSC|EnsemblGenome=LOC121833825|UniProtKB=A0ACM8FLW5 A0ACM8FLW5 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331295|UniProtKB=A0ACM8ENI5 A0ACM8ENI5 LOC115331295 PTHR24381:SF486 ZINC FINGER PROTEIN ADULT ENHANCER FACTOR 1-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8043615|UniProtKB=A0ACM8DGT0 A0ACM8DGT0 eIF1 PTHR10388:SF87 EUKARYOTIC TRANSLATION INITIATION FACTOR SUI1 EUKARYOTIC TRANSLATION INITIATION FACTOR EIF1 translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743;binding#GO:0005488;nucleic acid binding#GO:0003676;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8027789|UniProtKB=A0ACM8DJD8 A0ACM8DJD8 LOC8027789 PTHR10704:SF44 CARBOHYDRATE SULFOTRANSFERASE LD35051P-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121833102|UniProtKB=A0ACM8FJI0 A0ACM8FJI0 LOC121833102 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8023685|UniProtKB=A0ACM8DUN8 A0ACM8DUN8 LOC8023685 PTHR21600:SF94 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD1 intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8038436|UniProtKB=A0ACM8EYE2 A0ACM8EYE2 LOC8038436 PTHR23382:SF34 MALATE DEHYDROGENASE MALATE DEHYDROGENASE, CYTOPLASMIC oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;oxoacid metabolic process#GO:0043436;pyridine-containing compound metabolic process#GO:0072524;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 TCA cycle#P00051>Malate Dehydrogenase#P01270 IXOSC|EnsemblGenome=LOC115330363|UniProtKB=A0ACM8ERN1 A0ACM8ERN1 LOC115330363 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC120846884|UniProtKB=A0ACM8F3F3 A0ACM8F3F3 LOC120846884 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025419|UniProtKB=A0ACM8DJ94 A0ACM8DJ94 PTHR19282:SF519 TETRASPANIN TETRASPANIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8036616|UniProtKB=A0ACM8EXP9 A0ACM8EXP9 LOC8036616 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115324842|UniProtKB=A0ACM8EZR6 A0ACM8EZR6 LOC115324842 PTHR11610:SF204 LIPASE PHOSPHOLIPASE A1 1-LIKE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8029473|UniProtKB=A0ACM8E383 A0ACM8E383 Mcm10 PTHR13454:SF11 PROTEIN MCM10 HOMOLOG PROTEIN MCM10 HOMOLOG sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120844185|UniProtKB=A0ACM8EY18 A0ACM8EY18 LOC120844185 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC120849051|UniProtKB=A0ACM8F613 A0ACM8F613 PTHR12812:SF0 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC115322476|UniProtKB=A0ACM8FB12 A0ACM8FB12 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121045821|UniProtKB=A0ACM8FC54 A0ACM8FC54 LOC121045821 PTHR11532:SF96 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 IXOSC|EnsemblGenome=LOC8051049|UniProtKB=A0ACM8ECI2 A0ACM8ECI2 LOC8051049 PTHR38332:SF1 PROTEIN CBG11604 RE49668P IXOSC|EnsemblGenome=LOC8037559|UniProtKB=A0ACM8FFS1 A0ACM8FFS1 LOC8037559 PTHR15871:SF5 PH DOMAIN-CONTAINING PROTEIN PX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028238|UniProtKB=A0ACM8G609 A0ACM8G609 LOC8028238 PTHR23220:SF83 INTEGRIN ALPHA INTEGRIN ALPHA-PS3-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;cell-cell adhesion#GO:0098609 cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;integrin complex#GO:0008305;signaling receptor complex#GO:0043235 cell adhesion molecule#PC00069;integrin#PC00126 Integrin signalling pathway#P00034>Integrin alpha#P00941 IXOSC|EnsemblGenome=LOC8035310|UniProtKB=A0ACM8DW78 A0ACM8DW78 LOC8035310 PTHR13190:SF1 AUTOPHAGY-RELATED 2, ISOFORM A AUTOPHAGY-RELATED PROTEIN 2 lipid binding#GO:0008289;protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543 organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;reticulophagy#GO:0061709;glycogen catabolic process#GO:0005980;macroautophagy#GO:0016236;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607 phagophore assembly site#GO:0000407;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8036081|UniProtKB=A0ACM8E4Q1 A0ACM8E4Q1 LOC8036081 PTHR32078:SF2 NUCLEAR PROTEIN MDM1 NUCLEAR PROTEIN MDM1 protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 regulation of microtubule-based process#GO:0032886;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;centriole#GO:0005814;centriolar satellite#GO:0034451;microtubule cytoskeleton#GO:0015630 IXOSC|EnsemblGenome=LOC8027253|UniProtKB=A0ACM8DNJ8 A0ACM8DNJ8 LOC8027253 PTHR11615:SF372 NITRATE, FORMATE, IRON DEHYDROGENASE CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR CG17683-RELATED iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC115309461|UniProtKB=A0ACM8DNV1 A0ACM8DNV1 LOC115309461 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033331|UniProtKB=A0ACM8E367 A0ACM8E367 LOC8033331 PTHR12451:SF0 TRANSCRIPTION FACTOR CASTOR PROTEIN MING -RELATED ZINC FINGER PROTEIN CASTOR HOMOLOG 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of cell differentiation#GO:0045595;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of neuron differentiation#GO:0045664;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120844576|UniProtKB=A0ACM8FTG6 A0ACM8FTG6 LOC120844576 PTHR48025:SF30 OS02G0815200 PROTEIN RIBONUCLEOPROTEIN, PTB BINDING 1 IXOSC|EnsemblGenome=LOC120850509|UniProtKB=A0ACM8G2W4 A0ACM8G2W4 LOC120850509 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115328488|UniProtKB=A0ACM8E9J3 A0ACM8E9J3 LOC115328488 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 IXOSC|EnsemblGenome=LOC120849585|UniProtKB=A0ACM8G0E4 A0ACM8G0E4 LOC120849585 PTHR45695:SF26 LEUCOKININ RECEPTOR-RELATED NEUROPEPTIDE CCHAMIDE-1 RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120837176|UniProtKB=A0ACM8EGS0 A0ACM8EGS0 Pdi PTHR18929:SF240 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096;protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;response to stress#GO:0006950;biosynthetic process#GO:0009058;protein folding#GO:0006457;response to stimulus#GO:0050896;protein maturation#GO:0051604;gene expression#GO:0010467;cellular response to stress#GO:0033554;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8026736|UniProtKB=A0ACM8G137 A0ACM8G137 LOC8026736 PTHR24251:SF43 OVOCHYMASE-RELATED METALLOENDOPEPTIDASE protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8040925|UniProtKB=A0ACM8G0L5 A0ACM8G0L5 Lrrk PTHR24198:SF169 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121838168|UniProtKB=A0ACM8G6N1 A0ACM8G6N1 LOC121838168 PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 molecular function activator activity#GO:0140677;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;enzyme binding#GO:0019899;binding#GO:0005488;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;nucleocytoplasmic transport#GO:0006913;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;perinuclear region of cytoplasm#GO:0048471;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120844321|UniProtKB=A0ACM8EYH8 A0ACM8EYH8 LOC120844321 PTHR11743:SF70 VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL GH26960P-RELATED voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 mitochondrial transport#GO:0006839;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular localization#GO:0051641;mitochondrial transmembrane transport#GO:1990542;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737 voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC120838399|UniProtKB=A0ACM8FEJ4 A0ACM8FEJ4 LOC120838399 PTHR12001:SF55 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2 transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;isoprenoid biosynthetic process#GO:0008299;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;isoprenoid metabolic process#GO:0006720 mitochondrion#GO:0005739;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115312085|UniProtKB=A0ACM8F5T5 A0ACM8F5T5 LOC115312085 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115325597|UniProtKB=A0ACM8F1Z6 A0ACM8F1Z6 LOC115325597 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8031992|UniProtKB=A0ACM8DJ19 A0ACM8DJ19 LOC8031992 PTHR24376:SF216 ZINC FINGER PROTEIN DRACULIN-LIKE 3 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115311195|UniProtKB=A0ACM8FAN6 A0ACM8FAN6 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844239|UniProtKB=A0ACM8EXV8 A0ACM8EXV8 LOC120844239 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850406|UniProtKB=A0ACM8F8Q4 A0ACM8F8Q4 LOC120850406 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120836352|UniProtKB=A0ACM8EEG1 A0ACM8EEG1 LOC120836352 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120843027|UniProtKB=A0ACM8EUY8 A0ACM8EUY8 LOC120843027 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120842498|UniProtKB=A0ACM8ETS2 A0ACM8ETS2 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031751|UniProtKB=A0ACM8DU92 A0ACM8DU92 LOC8031751 PTHR19282:SF564 TETRASPANIN TETRASPANIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121837950|UniProtKB=A0ACM8G6X1 A0ACM8G6X1 LOC121837950 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036235|UniProtKB=A0ACM8DHA4 A0ACM8DHA4 LOC8036235 PTHR47385:SF14 CALPONIN TRANSGELIN actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 actin filament-based process#GO:0030029;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 IXOSC|EnsemblGenome=LOC115332667|UniProtKB=A0ACM8EEU0 A0ACM8EEU0 LOC115332667 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842133|UniProtKB=A0ACM8ET70 A0ACM8ET70 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030669|UniProtKB=A0ACM8FS73 A0ACM8FS73 LOC8030669 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120848078|UniProtKB=A0ACM8F5D9 A0ACM8F5D9 LOC120848078 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8037066|UniProtKB=A0ACM8DMV9 A0ACM8DMV9 LOC8037066 PTHR42801:SF4 THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE THIOREDOXIN-DEPENDENT PEROXIREDOXIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 homeostatic process#GO:0042592;cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 peroxidase#PC00180 IXOSC|EnsemblGenome=LOC115317299|UniProtKB=A0ACM8EUK5 A0ACM8EUK5 LOC115317299 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8033002|UniProtKB=A0ACM8F5A6 A0ACM8F5A6 LOC8033002 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8043997|UniProtKB=A0ACM8DRZ9 A0ACM8DRZ9 LOC8043997 PTHR24349:SF527 SERINE/THREONINE-PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;binding#GO:0005488;calcium/calmodulin-dependent protein kinase activity#GO:0004683;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;calmodulin binding#GO:0005516;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8023666|UniProtKB=A0ACM8DUF6 A0ACM8DUF6 LOC8023666 PTHR15859:SF1 SETA BINDING PROTEIN 1 BTB DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120845926|UniProtKB=A0ACM8F0D1 A0ACM8F0D1 LOC120845926 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314827|UniProtKB=A0ACM8DUJ5 A0ACM8DUJ5 LOC115314827 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120841897|UniProtKB=A0ACM8ESC7 A0ACM8ESC7 LOC120841897 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC8030198|UniProtKB=A0ACM8ELR4 A0ACM8ELR4 LOC8030198 PTHR13627:SF32 FUKUTIN RELATED PROTEIN LICD_FKTN_FKRP NUCLEOTIDYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319476|UniProtKB=A0ACM8FVH5 A0ACM8FVH5 LOC115319476 PTHR24279:SF120 CYTOCHROME P450 SHD ECDYSTEROID 20-HYDROXYLASE, 20-HYDROXYECDYSONE BIOSYNTHESIS-RELATED IXOSC|EnsemblGenome=LOC8025124|UniProtKB=A0ACM8DJ14 A0ACM8DJ14 Hph PTHR12907:SF26 EGL NINE HOMOLOG-RELATED HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASE IXOSC|EnsemblGenome=LOC120850213|UniProtKB=A0ACM8FAE1 A0ACM8FAE1 LOC120850213 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311526|UniProtKB=A0ACM8F9J6 A0ACM8F9J6 LOC115311526 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8030447|UniProtKB=A0ACM8FED9 A0ACM8FED9 LOC8030447 PTHR46315:SF1 SPERMINE SYNTHASE SPERMINE SYNTHASE transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740 biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596;polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308 IXOSC|EnsemblGenome=LOC8036611|UniProtKB=A0ACM8DHJ1 A0ACM8DHJ1 LOC8036611 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC-RELATED protein binding#GO:0005515;binding#GO:0005488 dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 IXOSC|EnsemblGenome=LOC115310409|UniProtKB=A0ACM8DPV7 A0ACM8DPV7 LOC115310409 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034046|UniProtKB=A0ACM8DIT5 A0ACM8DIT5 LOC8034046 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120840905|UniProtKB=A0ACM8G5R5 A0ACM8G5R5 LOC120840905 PTHR13516:SF30 RIBONUCLEASE P SUBUNIT P25 FI09323P RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170 ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;catalytic complex#GO:1902494;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular protein-containing complex#GO:0140535 RNA metabolism protein#PC00031;endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC8033929|UniProtKB=A0ACM8DM89 A0ACM8DM89 stck PTHR24210:SF0 LIM DOMAIN-CONTAINING PROTEIN LIM DOMAIN-CONTAINING PROTEIN positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;regulation of cell communication#GO:0010646;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell-cell adhesion#GO:0098609;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cell-cell junction organization#GO:0045216;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cell junction protein#PC00070 Integrin signalling pathway#P00034>PINCH#P00921 IXOSC|EnsemblGenome=LOC120850234|UniProtKB=A0ACM8F8D2 A0ACM8F8D2 LOC120850234 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8043266|UniProtKB=A0ACM8ED63 A0ACM8ED63 GTPBP1 PTHR43721:SF9 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 1 translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational elongation#GO:0006414;translation#GO:0006412 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC120845182|UniProtKB=A0ACM8F155 A0ACM8F155 LOC120845182 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027997|UniProtKB=A0ACM8G1W9 A0ACM8G1W9 LOC8027997 PTHR18945:SF895 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA3, ISOFORM B monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligand-gated monoatomic cation channel activity#GO:0099094;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231 cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, cholinergic#GO:0007271;transport#GO:0006810;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 IXOSC|EnsemblGenome=LOC8034906|UniProtKB=A0ACM8EE57 A0ACM8EE57 LOC8034906 PTHR12262:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 9 metabolic process#GO:0008152;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;regulation of mRNA metabolic process#GO:1903311;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of mRNA stability#GO:0043488;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;CCR4-NOT complex#GO:0030014;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;P-body#GO:0000932;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8039976|UniProtKB=A0ACM8DMU0 A0ACM8DMU0 LOC8039976 PTHR24300:SF434 CYTOCHROME P450 508A4-RELATED STEROID 21-HYDROXYLASE tetrapyrrole binding#GO:0046906;binding#GO:0005488;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121833448|UniProtKB=A0ACM8FL68 A0ACM8FL68 LOC121833448 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332710|UniProtKB=A0ACM8FCE9 A0ACM8FCE9 mio PTHR16453:SF9 WD40 DOMAIN-CONTAINING PROTEIN MIO FAMILY MEMBER GATOR2 COMPLEX PROTEIN MIOS cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;positive regulation of TORC1 signaling#GO:1904263;response to stress#GO:0006950;response to nutrient levels#GO:0031667;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;cellular response to amino acid starvation#GO:0034198;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;response to starvation#GO:0042594;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8040327|UniProtKB=A0ACM8DS56 A0ACM8DS56 LOC8040327 PTHR11214:SF235 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115309468|UniProtKB=A0ACM8DNW0 A0ACM8DNW0 PTHR11599:SF13 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-4 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytosol#GO:0005829;nucleus#GO:0005634;proteasome complex#GO:0000502;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;protease#PC00190 Parkinson disease#P00049>20S proteasome#P01227 IXOSC|EnsemblGenome=LOC8043304|UniProtKB=A0ACM8E2S5 A0ACM8E2S5 LOC8043304 PTHR12174:SF103 SIGNAL PEPTIDE PEPTIDASE INTRAMEMBRANE PROTEASE (IMPAS) FAMILY aspartic protease#PC00053;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121838101|UniProtKB=A0ACM8G6F2 A0ACM8G6F2 LOC121838101 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121047636|UniProtKB=A0ACM8FGH8 A0ACM8FGH8 LOC121047636 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121838055|UniProtKB=A0ACM8G7Q7 A0ACM8G7Q7 LOC121838055 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046061|UniProtKB=A0ACM8FD28 A0ACM8FD28 LOC121046061 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115310459|UniProtKB=A0ACM8F5E6 A0ACM8F5E6 LOC115310459 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=ISCI021924|UniProtKB=Q4PM04 Q4PM04 RpL18 PTHR10934:SF2 60S RIBOSOMAL PROTEIN L18 LARGE RIBOSOMAL SUBUNIT PROTEIN EL18 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC115309992|UniProtKB=A0ACM8DP67 A0ACM8DP67 LOC115309992 PTHR43601:SF39 THIOREDOXIN, MITOCHONDRIAL THIOREDOXIN, MITOCHONDRIAL cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Hypoxia response via HIF activation#P00030>Thioredoxin#P00825 IXOSC|EnsemblGenome=LOC8050615|UniProtKB=A0ACM8DWT2 A0ACM8DWT2 LOC8050615 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120838444|UniProtKB=A0ACM8EK06 A0ACM8EK06 LOC120838444 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326497|UniProtKB=A0ACM8E606 A0ACM8E606 Hel89B PTHR36498:SF1 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172 IXOSC|EnsemblGenome=LOC8039173|UniProtKB=A0ACM8E1F6 A0ACM8E1F6 LOC8039173 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293 monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC120848483|UniProtKB=A0ACM8F5Q0 A0ACM8F5Q0 PTHR36943:SF2 CCHC-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053250|UniProtKB=A0ACM8E4Y6 A0ACM8E4Y6 Strip PTHR13239:SF4 PROTEIN REQUIRED FOR HYPHAL ANASTOMOSIS HAM-2 AT25231P protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8050900|UniProtKB=A0ACM8E4F7 A0ACM8E4F7 LOC8050900 PTHR13366:SF0 MALARIA ANTIGEN-RELATED HEAT REPEAT-CONTAINING PROTEIN 6 IXOSC|EnsemblGenome=LOC120848335|UniProtKB=A0ACM8FI36 A0ACM8FI36 LOC120848335 PTHR43782:SF5 ARGINASE ARGINASE ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;hydrolase activity#GO:0016787;metal ion binding#GO:0046872;cation binding#GO:0043169;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115309499|UniProtKB=A0ACM8DNQ7 A0ACM8DNQ7 LOC115309499 PTHR11893:SF47 INNEXIN INNEXIN-5 channel activity#GO:0015267;wide pore channel activity#GO:0022829;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 gap junction#PC00105 IXOSC|EnsemblGenome=LOC115308604|UniProtKB=A0ACM8DMP5 A0ACM8DMP5 LOC115308604 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115326137|UniProtKB=A0ACM8FQP0 A0ACM8FQP0 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC115311420|UniProtKB=A0ACM8DR16 A0ACM8DR16 LOC115311420 PTHR21014:SF6 PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 4-PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatidylinositol dephosphorylation#GO:0046856;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;dephosphorylation#GO:0016311;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;phospholipid dephosphorylation#GO:0046839;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644 membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;late endosome membrane#GO:0031902;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;phagocytic vesicle#GO:0045335;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121838324|UniProtKB=A0ACM8G7G3 A0ACM8G7G3 LOC121838324 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327905|UniProtKB=A0ACM8FZ56 A0ACM8FZ56 LOC115327905 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037865|UniProtKB=A0ACM8G888 A0ACM8G888 LOC8037865 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8042985|UniProtKB=A0ACM8DL19 A0ACM8DL19 LOC8042985 PTHR15959:SF0 SYNTAXIN-18 SYNTAXIN-18 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;membrane#GO:0016020;membrane protein complex#GO:0098796 membrane traffic protein#PC00150;SNARE protein#PC00034 IXOSC|EnsemblGenome=LOC115325724|UniProtKB=A0ACM8EKU1 A0ACM8EKU1 LOC115325724 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115314438|UniProtKB=A0ACM8FUQ6 A0ACM8FUQ6 LOC115314438 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026806|UniProtKB=A0ACM8DYN4 A0ACM8DYN4 MED6 PTHR13104:SF0 MED-6-RELATED MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 6 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120841605|UniProtKB=A0ACM8FG70 A0ACM8FG70 LOC120841605 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115319632|UniProtKB=A0ACM8DZG8 A0ACM8DZG8 LOC115319632 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8042145|UniProtKB=A0ACM8EIA3 A0ACM8EIA3 PTHR11590:SF69 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 transferase#PC00220 IXOSC|EnsemblGenome=LOC8024510|UniProtKB=A0ACM8EAD4 A0ACM8EAD4 LOC8024510 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;protein sumoylation#GO:0016925;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 IXOSC|EnsemblGenome=LOC8033478|UniProtKB=A0ACM8DVV7 A0ACM8DVV7 PTHR24171:SF15 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 50-RELATED IXOSC|EnsemblGenome=LOC120849602|UniProtKB=A0ACM8F8G0 A0ACM8F8G0 LOC120849602 PTHR10003:SF71 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN]-RELATED cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;oxidoreductase activity#GO:0016491;copper ion binding#GO:0005507;catalytic activity#GO:0003824;antioxidant activity#GO:0016209 cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;response to reactive oxygen species#GO:0000302;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to stress#GO:0006950;cellular process#GO:0009987;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120839968|UniProtKB=A0ACM8FE60 A0ACM8FE60 LOC120839968 PTHR31553:SF1 NF-KAPPA-B ESSENTIAL MODULATOR OPTINEURIN-LIKE ISOFORM X1 K63-linked polyubiquitin modification-dependent protein binding#GO:0070530;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;protein binding#GO:0005515 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115309678|UniProtKB=A0ACM8DP31 A0ACM8DP31 LOC115309678 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8026891|UniProtKB=A0ACM8DII3 A0ACM8DII3 LOC8026891 PTHR12734:SF0 METHYLTRANSFERASE-RELATED 18S RRNA (GUANINE-N(7))-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity, acting on RNA#GO:0140098;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102 transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;rRNA metabolic process#GO:0016072;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosomal small subunit export from nucleus#GO:0000056;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;organelle localization#GO:0051640;nuclear export#GO:0051168;rRNA processing#GO:0006364;nuclear transport#GO:0051169;localization#GO:0051179;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA metabolic process#GO:0016070;cellular localization#GO:0051641;ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115332555|UniProtKB=A0ACM8EQS6 A0ACM8EQS6 LOC115332555 PTHR43767:SF1 LONG-CHAIN-FATTY-ACID--COA LIGASE NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC8051748|UniProtKB=A0ACM8FJL1 A0ACM8FJL1 LOC8051748 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120839126|UniProtKB=A0ACM8ELK1 A0ACM8ELK1 LOC120839126 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8024663|UniProtKB=A0ACM8FEC9 A0ACM8FEC9 LOC8024663 PTHR24252:SF41 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11D-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120846781|UniProtKB=A0ACM8F430 A0ACM8F430 LOC120846781 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027521|UniProtKB=A0ACM8E3A4 A0ACM8E3A4 LOC8027521 PTHR11958:SF63 SODIUM/DICARBOXYLATE SYMPORTER-RELATED AMINO ACID TRANSPORTER symporter activity#GO:0015293;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-amino acid transmembrane transporter activity#GO:0015179;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;acidic amino acid transmembrane transporter activity#GO:0015172 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;L-glutamate import#GO:0051938;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;acidic amino acid transport#GO:0015800;carboxylic acid transport#GO:0046942;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 IXOSC|EnsemblGenome=LOC115320396|UniProtKB=A0ACM8E0W4 A0ACM8E0W4 LOC115320396 PTHR21588:SF18 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 6 MICOS COMPLEX SUBUNIT MIC19 cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component organization#GO:0016043;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrion organization#GO:0007005;membrane organization#GO:0061024 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115317370|UniProtKB=A0ACM8G1U3 A0ACM8G1U3 LOC115317370 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8026941|UniProtKB=A0ACM8DU38 A0ACM8DU38 LOC8026941 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120847475|UniProtKB=A0ACM8F518 A0ACM8F518 LOC120847475 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121046642|UniProtKB=A0ACM8FXK5 A0ACM8FXK5 LOC121046642 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115317650|UniProtKB=A0ACM8DXQ8 A0ACM8DXQ8 LOC115317650 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121835109|UniProtKB=A0ACM8FTF5 A0ACM8FTF5 LOC121835109 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121833911|UniProtKB=A0ACM8FPH3 A0ACM8FPH3 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121048314|UniProtKB=A0ACM8G546 A0ACM8G546 LOC121048314 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC115320746|UniProtKB=A0ACM8E0I4 A0ACM8E0I4 LOC115320746 PTHR16007:SF15 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B-LIKE IXOSC|EnsemblGenome=LOC8033465|UniProtKB=A0ACM8DXA1 A0ACM8DXA1 CCT6 PTHR11353:SF21 CHAPERONIN CHAPERONIN CONTAINING TCP1 SUBUNIT 6A-RELATED gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 chaperonin#PC00073 IXOSC|EnsemblGenome=LOC120846402|UniProtKB=A0ACM8F358 A0ACM8F358 LOC120846402 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840461|UniProtKB=A0ACM8EQ76 A0ACM8EQ76 LOC120840461 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115320541|UniProtKB=A0ACM8EKP3 A0ACM8EKP3 LOC115320541 PTHR22930:SF269 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042218|UniProtKB=A0ACM8G8N4 A0ACM8G8N4 LOC8042218 PTHR12837:SF15 POLY ADP-RIBOSE GLYCOHYDROLASE POLY(ADP-RIBOSE) GLYCOHYDROLASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide metabolic process#GO:0009259;regulation of cellular response to stress#GO:0080135;nucleotide metabolic process#GO:0009117;regulation of DNA metabolic process#GO:0051052;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;macromolecule metabolic process#GO:0043170;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;regulation of metabolic process#GO:0019222;organophosphate metabolic process#GO:0019637;regulation of primary metabolic process#GO:0080090;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8051981|UniProtKB=A0ACM8E530 A0ACM8E530 LOC8051981 PTHR46447:SF1 INTERLEUKIN ENHANCER-BINDING FACTOR INTERLEUKIN ENHANCER-BINDING FACTOR 2 RNA binding#GO:0003723;DNA binding#GO:0003677;double-stranded RNA binding#GO:0003725;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC8029149|UniProtKB=A0ACM8DHN9 A0ACM8DHN9 MagR PTHR10072:SF41 IRON-SULFUR CLUSTER ASSEMBLY PROTEIN IRON-SULFUR CLUSTER ASSEMBLY 1 HOMOLOG, MITOCHONDRIAL iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;iron-sulfur cluster assembly#GO:0016226;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein metabolic process#GO:0019538;metabolic process#GO:0008152 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8038661|UniProtKB=A0ACM8DP34 A0ACM8DP34 LOC8038661 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120838547|UniProtKB=A0ACM8EJH5 A0ACM8EJH5 LOC120838547 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8025937|UniProtKB=A0ACM8DZ47 A0ACM8DZ47 LOC8025937 PTHR10695:SF46 DEPHOSPHO-COA KINASE-RELATED DEPHOSPHO-COA KINASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 kinase#PC00137;metabolite interconversion enzyme#PC00262 Coenzyme A biosynthesis#P02736>Pantetheine-phosphate adenyltransferase#P02886;Coenzyme A biosynthesis#P02736>Dephospho-CoA kinase#P02884 IXOSC|EnsemblGenome=LOC115331161|UniProtKB=A0ACM8EC95 A0ACM8EC95 LOC115331161 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8037754|UniProtKB=A0ACM8EBU6 A0ACM8EBU6 LOC8037754 PTHR12832:SF11 TESTIS-SPECIFIC PROTEIN PBS13 T-COMPLEX 11 LD23868P cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC120844710|UniProtKB=A0ACM8G6W7 A0ACM8G6W7 LOC120844710 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8030470|UniProtKB=A0ACM8E6R3 A0ACM8E6R3 SmB PTHR10701:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B AND N SMALL NUCLEAR RIBONUCLEOPROTEIN-ASSOCIATED PROTEIN B binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;protein-containing complex binding#GO:0044877 mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;U4 snRNP#GO:0005687;U2-type prespliceosome#GO:0071004;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;U4/U6 x U5 tri-snRNP complex#GO:0046540;cytoplasm#GO:0005737;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC121837836|UniProtKB=A0ACM8G508 A0ACM8G508 LOC121837836 PTHR45632:SF36 LD33804P RING ZINC FINGER-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8033196|UniProtKB=A0ACM8FR92 A0ACM8FR92 LOC8033196 PTHR24228:SF59 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR NEUROPEPTIDE RECEPTOR 15 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121834003|UniProtKB=A0ACM8FPU5 A0ACM8FPU5 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8035776|UniProtKB=A0ACM8DNX1 A0ACM8DNX1 LOC8035776 PTHR10846:SF73 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER CG1090-RELATED transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;antiporter activity#GO:0015297;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8043437|UniProtKB=A0ACM8E1M8 A0ACM8E1M8 Samtor PTHR21008:SF2 S-ADENOSYLMETHIONINE SENSOR UPSTREAM OF MTORC1-RELATED S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE-RELATED molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299 IXOSC|EnsemblGenome=LOC8035109|UniProtKB=A0ACM8G6N8 A0ACM8G6N8 SCAP PTHR46378:SF1 STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN STEROL REGULATORY ELEMENT-BINDING PROTEIN CLEAVAGE-ACTIVATING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of lipid biosynthetic process#GO:0046890;regulation of steroid biosynthetic process#GO:0050810;biological regulation#GO:0065007;SREBP signaling pathway#GO:0032933;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of lipid metabolic process#GO:0019216;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC121046973|UniProtKB=A0ACM8FFD9 A0ACM8FFD9 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8041604|UniProtKB=A0ACM8DKR6 A0ACM8DKR6 LOC8041604 PTHR13693:SF3 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE C-PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520;alcohol metabolic process#GO:0006066;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;ceramide biosynthetic process#GO:0046513 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991 transaminase#PC00216 IXOSC|EnsemblGenome=LOC8037568|UniProtKB=A0ACM8DTE4 A0ACM8DTE4 LOC8037568 PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell cycle#GO:0007049 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8035160|UniProtKB=A0ACM8FCQ6 A0ACM8FCQ6 Zw PTHR23429:SF23 GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE G6PD GLUCOSE-6-PHOSPHATE 1-DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;glucose-6-phosphate dehydrogenase activity#GO:0004345 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;pentose-phosphate shunt, oxidative branch#GO:0009051;generation of precursor metabolites and energy#GO:0006091;glucose metabolic process#GO:0006006;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;nucleotide metabolic process#GO:0009117;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121834722|UniProtKB=A0ACM8FPL6 A0ACM8FPL6 PTHR12824:SF8 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GXIVSPLA2, ISOFORM A hydrolase#PC00121;phospholipase#PC00186;lipase#PC00143 IXOSC|EnsemblGenome=LOC115312880|UniProtKB=A0ACM8DSH0 A0ACM8DSH0 Got2 PTHR11879:SF58 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 transaminase#PC00216;transferase#PC00220;metabolite interconversion enzyme#PC00262 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 IXOSC|EnsemblGenome=LOC115317132|UniProtKB=A0ACM8DX82 A0ACM8DX82 LOC115317132 PTHR24376:SF216 ZINC FINGER PROTEIN DRACULIN-LIKE 3 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120850792|UniProtKB=A0ACM8F9R7 A0ACM8F9R7 LOC120850792 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8042169|UniProtKB=A0ACM8EXZ8 A0ACM8EXZ8 LOC8042169 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8042541|UniProtKB=A0ACM8DRN4 A0ACM8DRN4 nudE PTHR10921:SF4 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG 1 NUCLEAR DISTRIBUTION PROTEIN NUDE HOMOLOG binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of mitotic spindle localization#GO:0040001;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;establishment of vesicle localization#GO:0051650;organelle transport along microtubule#GO:0072384;chromosome localization#GO:0050000;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule organizing center organization#GO:0031023;protein-containing complex organization#GO:0043933;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;microtubule nucleation#GO:0007020;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;centrosome cycle#GO:0007098;protein polymerization#GO:0051258;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;establishment of organelle localization#GO:0051656;centrosome localization#GO:0051642;establishment or maintenance of cell polarity#GO:0007163;nuclear division#GO:0000280;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;spindle localization#GO:0051653;microtubule polymerization or depolymerization#GO:0031109;vesicle localization#GO:0051648;establishment of spindle localization#GO:0051293;cytoskeleton-dependent intracellular transport#GO:0030705;cell migration#GO:0016477;vesicle transport along microtubule#GO:0047496;intracellular transport#GO:0046907;transport#GO:0006810;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;vesicle cytoskeletal trafficking#GO:0099518;mitotic cell cycle process#GO:1903047;microtubule polymerization#GO:0046785;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;establishment of cell polarity#GO:0030010;mitotic cell cycle#GO:0000278;cell motility#GO:0048870;microtubule-based movement#GO:0007018;organelle localization#GO:0051640;localization#GO:0051179;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435 membraneless organelle#GO:0043228;microtubule organizing center#GO:0005815;centrosome#GO:0005813;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;kinetochore#GO:0000776;chromosome#GO:0005694 IXOSC|EnsemblGenome=ISCI002768|UniProtKB=B7PCV3 B7PCV3 IscW_ISCW002768 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115310183|UniProtKB=A0ACM8FGB3 A0ACM8FGB3 LOC115310183 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8041001|UniProtKB=A0ACM8FA96 A0ACM8FA96 RpLP0-like PTHR45841:SF1 MRNA TURNOVER PROTEIN 4 MRTO4 MRNA TURNOVER PROTEIN 4 HOMOLOG negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC115318625|UniProtKB=A0ACM8DYP0 A0ACM8DYP0 LOC115318625 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832903|UniProtKB=A0ACM8G4P9 A0ACM8G4P9 LOC121832903 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC121834702|UniProtKB=A0ACM8FRP2 A0ACM8FRP2 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839450|UniProtKB=A0ACM8EL93 A0ACM8EL93 LOC120839450 PTHR36943:SF3 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026887|UniProtKB=A0ACM8DII6 A0ACM8DII6 PTHR10173:SF52 METHIONINE SULFOXIDE REDUCTASE METHIONINE-R-SULFOXIDE REDUCTASE B1 catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;reductase#PC00198 IXOSC|EnsemblGenome=LOC8053196|UniProtKB=A0ACM8FU81 A0ACM8FU81 LOC8053196 PTHR19282:SF565 TETRASPANIN TETRASPANIN-14 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8034651|UniProtKB=A0ACM8DJG8 A0ACM8DJG8 LOC8034651 PTHR12944:SF2 SOLUBLE LIVER ANTIGEN/LIVER PANCREAS ANTIGEN O-PHOSPHOSERYL-TRNA(SEC) SELENIUM TRANSFERASE RNA binding#GO:0003723;tRNA binding#GO:0000049;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;translational elongation#GO:0006414;metabolic process#GO:0008152;post-transcriptional regulation of gene expression#GO:0010608;biosynthetic process#GO:0009058;biological regulation#GO:0065007;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;protein metabolic process#GO:0019538;translation#GO:0006412;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein biosynthetic process#GO:0160307;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238 IXOSC|EnsemblGenome=LOC8023590|UniProtKB=A0ACM8DP12 A0ACM8DP12 LOC8023590 PTHR10151:SF131 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE CHOLINEPHOSPHODIESTERASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8031247|UniProtKB=A0ACM8DI35 A0ACM8DI35 vih PTHR24067:SF356 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 C intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491 IXOSC|EnsemblGenome=LOC120846649|UniProtKB=A0ACM8FVK5 A0ACM8FVK5 LOC120846649 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8036991|UniProtKB=A0ACM8DK17 A0ACM8DK17 LOC8036991 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033774|UniProtKB=A0ACM8E3J2 A0ACM8E3J2 LOC8033774 PTHR21277:SF5 TRANSCRIPTIONAL ADAPTER 1 TRANSCRIPTIONAL ADAPTER 1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;transferase complex#GO:1990234;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 IXOSC|EnsemblGenome=LOC120848484|UniProtKB=A0ACM8F6S9 A0ACM8F6S9 LOC120848484 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850764|UniProtKB=A0ACM8G798 A0ACM8G798 LOC120850764 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8039018|UniProtKB=A0ACM8FD10 A0ACM8FD10 LOC8039018 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC121046441|UniProtKB=A0ACM8FE26 A0ACM8FE26 LOC121046441 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8040623|UniProtKB=A0ACM8EZJ5 A0ACM8EZJ5 PTHR31397:SF1 BLOC-1-RELATED COMPLEX SUBUNIT 7 BORSC7 BLOC-1-RELATED COMPLEX SUBUNIT 7 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8050835|UniProtKB=A0ACM8DXS8 A0ACM8DXS8 LOC8050835 PTHR15937:SF3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 TRANSMEMBRANE 7 SUPERFAMILY MEMBER 3 negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121837920|UniProtKB=A0ACM8G6Q1 A0ACM8G6Q1 LOC121837920 PTHR45999:SF4 UNC-13-4A, ISOFORM B UNC-13-4A, ISOFORM B IXOSC|EnsemblGenome=LOC115319264|UniProtKB=A0ACM8DZT0 A0ACM8DZT0 PIG-C PTHR12982:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS C PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT C lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8052558|UniProtKB=A0ACM8EAQ3 A0ACM8EAQ3 LOC8052558 PTHR24064:SF714 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115332851|UniProtKB=A0ACM8EEQ9 A0ACM8EEQ9 LOC115332851 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041354|UniProtKB=A0ACM8F453 A0ACM8F453 LOC8041354 PTHR10579:SF178 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-LIKE ion channel#PC00133 IXOSC|EnsemblGenome=LOC115325294|UniProtKB=A0ACM8EVH8 A0ACM8EVH8 LOC115325294 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120840960|UniProtKB=A0ACM8EQQ8 A0ACM8EQQ8 LOC120840960 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261 signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;trans-synaptic signaling#GO:0099537;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC115318010|UniProtKB=A0ACM8F3P7 A0ACM8F3P7 LOC115318010 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120850082|UniProtKB=A0ACM8F954 A0ACM8F954 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043910|UniProtKB=A0ACM8EAJ2 A0ACM8EAJ2 RpII140 PTHR20856:SF7 DNA-DIRECTED RNA POLYMERASE I SUBUNIT 2 DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB2 catalytic activity, acting on RNA#GO:0140098;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;RNA polymerase II, core complex#GO:0005665;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC8050579|UniProtKB=A0ACM8ECX6 A0ACM8ECX6 PTHR14963:SF7 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN 19 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC8028746|UniProtKB=A0ACM8DN81 A0ACM8DN81 ABCD PTHR11384:SF67 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER ATP-BINDING CASSETTE SUB-FAMILY D MEMBER 1 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;transporter activity#GO:0005215;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;carboxylic acid transmembrane transporter activity#GO:0046943;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;nucleotide binding#GO:0000166;monocarboxylic acid transmembrane transporter activity#GO:0008028 lipid modification#GO:0030258;establishment of localization#GO:0051234;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;transport#GO:0006810;fatty acid metabolic process#GO:0006631;intracellular transport#GO:0046907;lipid transport#GO:0006869;monocarboxylic acid catabolic process#GO:0072329;carboxylic acid catabolic process#GO:0046395;macromolecule localization#GO:0033036;peroxisomal transport#GO:0043574;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;lipid oxidation#GO:0034440;carboxylic acid transmembrane transport#GO:1905039;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;fatty acid oxidation#GO:0019395;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;metabolic process#GO:0008152;establishment of localization in cell#GO:0051649;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organelle organization#GO:0006996;fatty acid catabolic process#GO:0009062;transmembrane transport#GO:0055085;cellular localization#GO:0051641;peroxisome organization#GO:0007031;lipid localization#GO:0010876;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120842473|UniProtKB=A0ACM8ETX3 A0ACM8ETX3 LOC120842473 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050657|UniProtKB=A0ACM8F2Y4 A0ACM8F2Y4 PTHR24338:SF0 HOMEOBOX PROTEIN MSX MUSCLE SEGMENTATION HOMEOBOX transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;regulation of biosynthetic process#GO:0009889;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC120844734|UniProtKB=A0ACM8EZI6 A0ACM8EZI6 LOC120844734 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120839984|UniProtKB=A0ACM8EMJ2 A0ACM8EMJ2 LOC120839984 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324518|UniProtKB=A0ACM8F8L2 A0ACM8F8L2 LOC115324518 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC115331924|UniProtKB=A0ACM8ECW8 A0ACM8ECW8 LOC115331924 PTHR46760:SF1 TRANSCRIPTION TERMINATION FACTOR 1 TRANSCRIPTION TERMINATION FACTOR 1 General transcription regulation#P00023>TTF2#P00661;General transcription by RNA polymerase I#P00022>TTF-I#P00654;Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 IXOSC|EnsemblGenome=LOC115325703|UniProtKB=A0ACM8E543 A0ACM8E543 LOC115325703 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115332794|UniProtKB=A0ACM8FU28 A0ACM8FU28 LOC115332794 PTHR44464:SF1 WD REPEAT-CONTAINING PROTEIN 17 WD REPEAT-CONTAINING PROTEIN 17 IXOSC|EnsemblGenome=LOC115330120|UniProtKB=A0ACM8G0M7 A0ACM8G0M7 LOC115330120 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115324932|UniProtKB=A0ACM8ERI7 A0ACM8ERI7 LOC115324932 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115329564|UniProtKB=A0ACM8EB56 A0ACM8EB56 eEFSec PTHR43721:SF11 ELONGATION FACTOR TU-RELATED SELENOCYSTEINE-SPECIFIC ELONGATION FACTOR translation elongation factor activity#GO:0003746;translation factor activity#GO:0180051 metabolic process#GO:0008152;translational elongation#GO:0006414;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;biosynthetic process#GO:0009058;gene expression#GO:0010467;translation#GO:0006412;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;protein biosynthetic process#GO:0160307;regulation of cellular process#GO:0050794 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC8025636|UniProtKB=A0ACM8EI88 A0ACM8EI88 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8039440|UniProtKB=A0ACM8DQ95 A0ACM8DQ95 LOC8039440 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC121836754|UniProtKB=A0ACM8G0F0 A0ACM8G0F0 LOC121836754 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329916|UniProtKB=A0ACM8ER12 A0ACM8ER12 LOC115329916 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120847759|UniProtKB=A0ACM8F4G7 A0ACM8F4G7 LOC120847759 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115318190|UniProtKB=A0ACM8DXP4 A0ACM8DXP4 MED23 PTHR12691:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 23 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889 mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8036525|UniProtKB=A0ACM8DJX3 A0ACM8DJX3 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8051544|UniProtKB=A0ACM8DV00 A0ACM8DV00 LOC8051544 PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC115312004|UniProtKB=A0ACM8ENS1 A0ACM8ENS1 LOC115312004 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8029176|UniProtKB=A0ACM8EXG1 A0ACM8EXG1 LOC8029176 PTHR45630:SF23 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE polyamine transmembrane transporter activity#GO:0015203;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic ion homeostasis#GO:0050801;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;transmembrane transport#GO:0055085 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121835556|UniProtKB=A0ACM8FVL1 A0ACM8FVL1 LOC121835556 PTHR22775:SF52 SORTING NEXIN FI21262P1 ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol binding#GO:0035091 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115332282|UniProtKB=A0ACM8EH36 A0ACM8EH36 LOC115332282 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311532|UniProtKB=A0ACM8FBM6 A0ACM8FBM6 LOC115311532 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842217|UniProtKB=A0ACM8ET19 A0ACM8ET19 LOC120842217 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323978|UniProtKB=A0ACM8E4T3 A0ACM8E4T3 LOC115323978 PTHR14339:SF12 VASCULIN VASCULIN IXOSC|EnsemblGenome=LOC8031180|UniProtKB=A0ACM8FRA0 A0ACM8FRA0 LOC8031180 PTHR47972:SF16 KINESIN-LIKE PROTEIN KLP-3 MYOSIN-RELATED PROTEIN microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC121837751|UniProtKB=A0ACM8G6A7 A0ACM8G6A7 LOC121837751 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8041008|UniProtKB=A0ACM8DX13 A0ACM8DX13 LOC8041008 PTHR19306:SF6 STRUCTURAL MAINTENANCE OF CHROMOSOMES 5,6 SMC5, SMC6 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 6 damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950 transferase complex#GO:1990234;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;nucleus#GO:0005634;site of double-strand break#GO:0035861;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8025743|UniProtKB=A0ACM8DRX2 A0ACM8DRX2 LOC8025743 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;protein folding#GO:0006457;protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to stress#GO:0006950;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC8031837|UniProtKB=A0ACM8EF67 A0ACM8EF67 LOC8031837 PTHR13006:SF9 PAPILLOMAVIRUS REGULATORY FACTOR PRF-1 GLUCOSE TRANSPORTER 4 ENHANCER FACTOR, ISOFORM G binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC115310054|UniProtKB=A0ACM8F0N6 A0ACM8F0N6 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8041886|UniProtKB=A0ACM8E3L0 A0ACM8E3L0 LOC8041886 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8030992|UniProtKB=A0ACM8DHU3 A0ACM8DHU3 LOC8030992 PTHR10015:SF477 HEAT SHOCK TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SFL2 gene-specific transcriptional regulator#PC00264;winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC121046039|UniProtKB=A0ACM8FX89 A0ACM8FX89 LOC121046039 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8024423|UniProtKB=A0ACM8G6V2 A0ACM8G6V2 LOC8024423 PTHR11848:SF309 TGF-BETA FAMILY INHIBIN BETA CHAIN signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125;receptor ligand activity#GO:0048018 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;Activin beta signaling pathway#P06210>activinbeta full length#P06232;TGF-beta signaling pathway#P00052>TGFbeta#P01286;Activin beta signaling pathway#P06210>activin beta#P06234 IXOSC|EnsemblGenome=LOC121833149|UniProtKB=A0ACM8FJQ5 A0ACM8FJQ5 LOC121833149 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120848669|UniProtKB=A0ACM8F6I3 A0ACM8F6I3 LOC120848669 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026185|UniProtKB=A0ACM8DPL2 A0ACM8DPL2 SCOT PTHR13707:SF23 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8023508|UniProtKB=A0ACM8EB93 A0ACM8EB93 LOC8023508 PTHR12845:SF5 GUANINE NUCLEOTIDE EXCHANGE FACTOR EPHEXIN, ISOFORM D guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin filament-based process#GO:0032970 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC115331023|UniProtKB=A0ACM8FAB3 A0ACM8FAB3 LOC115331023 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028269|UniProtKB=A0ACM8EPB0 A0ACM8EPB0 LOC8028269 PTHR42881:SF2 PROLYL ENDOPEPTIDASE PROLYL ENDOPEPTIDASE endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 Vasopressin synthesis#P04395>Endo Peptidase#P04596 IXOSC|EnsemblGenome=LOC8039870|UniProtKB=A0ACM8FN48 A0ACM8FN48 LOC8039870 PTHR45832:SF8 SERINE/THREONINE-PROTEIN KINASE SAMKA-RELATED-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE IXOSC|EnsemblGenome=LOC8033338|UniProtKB=A0ACM8E6Q1 A0ACM8E6Q1 LOC8033338 PTHR13174:SF3 D-GLUCURONYL C5-EPIMERASE D-GLUCURONYL C5-EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;proteoglycan biosynthetic process#GO:0030166 isomerase#PC00135 IXOSC|EnsemblGenome=LOC121837495|UniProtKB=A0ACM8G3P1 A0ACM8G3P1 LOC121837495 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC121046578|UniProtKB=A0ACM8FVV8 A0ACM8FVV8 LOC121046578 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8041308|UniProtKB=A0ACM8G3U9 A0ACM8G3U9 LOC8041308 PTHR47526:SF4 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8028477|UniProtKB=A0ACM8E8Q0 A0ACM8E8Q0 LOC8028477 PTHR43107:SF27 LONG-CHAIN FATTY ACID TRANSPORT PROTEIN LONG-CHAIN-FATTY-ACID--COA LIGASE carboxylic acid transmembrane transporter activity#GO:0046943;ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;catalytic activity#GO:0003824 lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;long-chain fatty acid metabolic process#GO:0001676;establishment of localization#GO:0051234;import into cell#GO:0098657;organic acid transport#GO:0015849;lipid metabolic process#GO:0006629;transport#GO:0006810;carboxylic acid transport#GO:0046942;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid transport#GO:0015718;fatty acid transport#GO:0015908;localization#GO:0051179;oxoacid metabolic process#GO:0043436;lipid localization#GO:0010876 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115321954|UniProtKB=A0ACM8E2C5 A0ACM8E2C5 LOC115321954 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121837376|UniProtKB=A0ACM8G315 A0ACM8G315 LOC121837376 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8034279|UniProtKB=A0ACM8F476 A0ACM8F476 LOC8034279 PTHR18966:SF448 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 3A-LIKE ligand-gated monoatomic ion channel activity#GO:0015276;carboxylic acid transmembrane transporter activity#GO:0046943;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216 cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, glutamatergic#GO:0035249;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8033645|UniProtKB=A0ACM8FBH3 A0ACM8FBH3 LOC8033645 PTHR16308:SF13 UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER PROTEIN LINGERER IXOSC|EnsemblGenome=LOC8028780|UniProtKB=A0ACM8E6J7 A0ACM8E6J7 LOC8028780 PTHR31432:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG INTRAFLAGELLAR TRANSPORT PROTEIN 74 HOMOLOG protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 cilium assembly#GO:0060271;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;microtubule-based transport#GO:0099111;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;intraciliary transport involved in cilium assembly#GO:0035735;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intraciliary transport particle B#GO:0030992;cilium#GO:0005929;intraciliary transport particle#GO:0030990;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115318460|UniProtKB=A0ACM8FJ37 A0ACM8FJ37 LOC115318460 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043 IXOSC|EnsemblGenome=LOC8027855|UniProtKB=A0ACM8FGC8 A0ACM8FGC8 LOC8027855 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120840305|UniProtKB=A0ACM8G4R6 A0ACM8G4R6 LOC121837384 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033979|UniProtKB=A0ACM8E7P4 A0ACM8E7P4 LOC8033979 PTHR10625:SF5 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE HDA1 catalytic activity#GO:0003824;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 cellular component organization#GO:0016043;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115332939|UniProtKB=A0ACM8EE38 A0ACM8EE38 LOC115332939 PTHR19957:SF435 SYNTAXIN HL02043P protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 cellular component organization#GO:0016043;vesicle fusion#GO:0006906;cytosolic transport#GO:0016482;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;synapse#GO:0045202;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;presynapse#GO:0098793;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658 SNARE protein#PC00034 IXOSC|EnsemblGenome=LOC8036174|UniProtKB=A0ACM8DJX2 A0ACM8DJX2 LOC8036174 PTHR11599:SF11 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;proteasome complex#GO:0000502 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 IXOSC|EnsemblGenome=LOC115323493|UniProtKB=A0ACM8FVB2 A0ACM8FVB2 LOC115323493 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC121047676|UniProtKB=A0ACM8FGE7 A0ACM8FGE7 PTHR46609:SF9 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323381|UniProtKB=A0ACM8E469 A0ACM8E469 LOC115323381 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121833961|UniProtKB=A0ACM8FNG9 A0ACM8FNG9 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115309236|UniProtKB=A0ACM8DNG3 A0ACM8DNG3 LOC115309236 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051504|UniProtKB=A0ACM8ELJ3 A0ACM8ELJ3 LOC8051504 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058;cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8042544|UniProtKB=A0ACM8ERV1 A0ACM8ERV1 LOC8042544 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8044109|UniProtKB=A0ACM8DL72 A0ACM8DL72 LOC8044109 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC121835572|UniProtKB=A0ACM8FW37 A0ACM8FW37 LOC121835572 PTHR11349:SF116 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleoside diphosphate kinase activity#GO:0004550;phosphotransferase activity, phosphate group as acceptor#GO:0016776 biosynthetic process#GO:0009058;nucleoside triphosphate metabolic process#GO:0009141;metabolic process#GO:0008152;nucleoside triphosphate biosynthetic process#GO:0009142;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transferase#PC00220;kinase#PC00137 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 IXOSC|EnsemblGenome=LOC121835954|UniProtKB=A0ACM8FVW7 A0ACM8FVW7 LOC121835954 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364 cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 transferase#PC00220 IXOSC|EnsemblGenome=LOC120841902|UniProtKB=A0ACM8ESP7 A0ACM8ESP7 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8042208|UniProtKB=A0ACM8E883 A0ACM8E883 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120841040|UniProtKB=A0ACM8ER18 A0ACM8ER18 LOC120841040 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC115315204|UniProtKB=A0ACM8DUL4 A0ACM8DUL4 LOC115315204 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121833529|UniProtKB=A0ACM8FLP9 A0ACM8FLP9 LOC121833529 PTHR19300:SF66 BETA-1,4-GALACTOSYLTRANSFERASE BETA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE A galactosyltransferase activity#GO:0008378;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8051281|UniProtKB=A0ACM8EGK4 A0ACM8EGK4 LOC8051281 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115333216|UniProtKB=A0ACM8EFC9 A0ACM8EFC9 LOC115333216 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8038100|UniProtKB=A0ACM8DN20 A0ACM8DN20 LOC8038100 PTHR22928:SF4 TELOMERE-ASSOCIATED PROTEIN RIF1 TELOMERE-ASSOCIATED PROTEIN RIF1 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;organelle organization#GO:0006996;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;chromosome, telomeric repeat region#GO:0140445;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome, telomeric region#GO:0000781 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8053013|UniProtKB=A0ACM8DR17 A0ACM8DR17 LOC8053013 PTHR45618:SF9 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL 2-OXOGLUTARATE_MALATE CARRIER PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8027061|UniProtKB=A0ACM8DIP0 A0ACM8DIP0 LOC8027061 PTHR28525:SF1 REACTIVE OXYGEN SPECIES MODULATOR 1 REACTIVE OXYGEN SPECIES MODULATOR 1 establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;protein import into mitochondrial matrix#GO:0030150;membrane organization#GO:0061024;protein insertion into mitochondrial inner membrane#GO:0045039;mitochondrion organization#GO:0007005;mitochondrial protein import pathway#GO:7770058;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;cellular component organization#GO:0016043;protein localization to mitochondrion#GO:0070585 inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121047618|UniProtKB=A0ACM8FGB4 A0ACM8FGB4 LOC121047618 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834739|UniProtKB=A0ACM8FRU7 A0ACM8FRU7 LOC121834739 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC121833438|UniProtKB=A0ACM8FL15 A0ACM8FL15 LOC121833438 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8051064|UniProtKB=A0ACM8DLV6 A0ACM8DLV6 LOC8051064 PTHR44340:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 10 ENDOPLASMIC RETICULUM DISULFIDE REDUCTASE DNAJC10 protein binding#GO:0005515;protein-disulfide reductase activity#GO:0015035;binding#GO:0005488;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;biological regulation#GO:0065007;response to stress#GO:0006950;endoplasmic reticulum unfolded protein response#GO:0030968;cellular process#GO:0009987;signal transduction#GO:0007165 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115324778|UniProtKB=A0ACM8FZP7 A0ACM8FZP7 LOC115324778 PTHR22625:SF61 PLEXIN HEPATOCYTE GROWTH FACTOR RECEPTOR molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;cell junction organization#GO:0034330;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell junction assembly#GO:0034329;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;regulation of cell migration#GO:0030334;developmental process#GO:0032502 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8034132|UniProtKB=A0ACM8ED38 A0ACM8ED38 Cog1 PTHR31658:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 1 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115330622|UniProtKB=A0ACM8G635 A0ACM8G635 LOC115330622 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8051850|UniProtKB=A0ACM8FGV1 A0ACM8FGV1 Snx21 PTHR20939:SF11 SORTING NEXIN 20, 21 LD12265P phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488 cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120848491|UniProtKB=A0ACM8F6T4 A0ACM8F6T4 LOC120848491 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329459|UniProtKB=A0ACM8EUG5 A0ACM8EUG5 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8026857|UniProtKB=A0ACM8FWQ2 A0ACM8FWQ2 LOC8026857 PTHR22957:SF502 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN SMALL G PROTEIN SIGNALING MODULATOR 2-RELATED GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120840740|UniProtKB=A0ACM8EQX2 A0ACM8EQX2 LOC120840740 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310446|UniProtKB=A0ACM8EP87 A0ACM8EP87 LOC115310446 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024206|UniProtKB=A0ACM8DZ52 A0ACM8DZ52 Rexo5 PTHR12801:SF82 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED RNA EXONUCLEASE 5 nuclease activity#GO:0004518;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC115319407|UniProtKB=A0ACM8DZV7 A0ACM8DZV7 Atox1 PTHR46365:SF1 COPPER TRANSPORT PROTEIN ATOX1 COPPER TRANSPORT PROTEIN ATOX1 molecular carrier activity#GO:0140104 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115309382|UniProtKB=A0ACM8DNN7 A0ACM8DNN7 LOC115309382 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308172|UniProtKB=A0ACM8ELW5 A0ACM8ELW5 LOC115308172 PTHR22753:SF14 TRANSMEMBRANE PROTEIN 68 DGAT1_2-INDEPENDENT ENZYME SYNTHESIZING STORAGE LIPIDS membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8026942|UniProtKB=A0ACM8DIJ6 A0ACM8DIJ6 LOC8026942 PTHR22957:SF645 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 15 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8050425|UniProtKB=A0ACM8E9Y3 A0ACM8E9Y3 Vps50 PTHR13258:SF0 SYNDETIN SYNDETIN protein binding#GO:0005515;SNARE binding#GO:0000149;binding#GO:0005488 endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810 intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC115320147|UniProtKB=A0ACM8F1J5 A0ACM8F1J5 LOC115320147 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035143|UniProtKB=A0ACM8DJQ9 A0ACM8DJQ9 pasi1 PTHR36694:SF13 PASIFLORA 1, ISOFORM A-RELATED PASIFLORA 1, ISOFORM A cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;gliogenesis#GO:0042063;regulation of anatomical structure size#GO:0090066;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;multicellular organismal process#GO:0032501;glial cell differentiation#GO:0010001;cellular component assembly#GO:0022607;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell junction organization#GO:0034330;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;cell junction assembly#GO:0034329 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8032431|UniProtKB=A0ACM8EQ18 A0ACM8EQ18 LOC8032431 PTHR31640:SF1 TRANSMEMBRANE PROTEIN KIAA1109 BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 1 synaptic vesicle recycling#GO:0036465;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;synaptic vesicle endocytosis#GO:0048488;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;synaptic vesicle cycle#GO:0099504;transport#GO:0006810 IXOSC|EnsemblGenome=LOC115329503|UniProtKB=A0ACM8FQ82 A0ACM8FQ82 LOC115329503 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027861|UniProtKB=A0ACM8DJE6 A0ACM8DJE6 LOC8027861 PTHR28637:SF1 DNA REPLICATION FACTOR CDT1 DNA REPLICATION FACTOR CDT1 binding#GO:0005488;nucleic acid binding#GO:0003676;enzyme binding#GO:0019899;protein binding#GO:0005515;DNA binding#GO:0003677 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA replication#GO:0006275;signaling#GO:0023052;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;regulation of DNA metabolic process#GO:0051052;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of DNA-templated DNA replication initiation#GO:0030174;regulation of nucleobase-containing compound metabolic process#GO:0019219;cell cycle checkpoint signaling#GO:0000075;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;regulation of metabolic process#GO:0019222 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120836189|UniProtKB=A0ACM8EFC3 A0ACM8EFC3 LOC120836189 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026279|UniProtKB=A0ACM8E0Z1 A0ACM8E0Z1 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120842722|UniProtKB=A0ACM8EUF6 A0ACM8EUF6 LOC120842722 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC121835987|UniProtKB=A0ACM8FXH2 A0ACM8FXH2 LOC121835987 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033096|UniProtKB=A0ACM8ECC7 A0ACM8ECC7 LOC8033096 PTHR11003:SF356 POTASSIUM CHANNEL, SUBFAMILY K RE21922P monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267;outward rectifier potassium channel activity#GO:0015271 transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC121838507|UniProtKB=A0ACM8G911 A0ACM8G911 LOC121838507 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121838381|UniProtKB=A0ACM8G8T4 A0ACM8G8T4 LOC121838381 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC8025065|UniProtKB=A0ACM8DSZ9 A0ACM8DSZ9 LOC8025065 PTHR15591:SF13 RUN AND SH3 DOMAIN CONTAINING RUN DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 IXOSC|EnsemblGenome=LOC120836841|UniProtKB=A0ACM8FY85 A0ACM8FY85 LOC120836841 PTHR11733:SF224 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-2 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8043753|UniProtKB=A0ACM8F3G9 A0ACM8F3G9 Lerp PTHR15071:SF17 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-INDEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR binding#GO:0005488;protein binding#GO:0005515;growth factor binding#GO:0019838 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;vacuolar transport#GO:0007034;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein targeting to vacuole#GO:0006623;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to vacuole#GO:0072665;lysosomal transport#GO:0007041;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein localization to lysosome#GO:0061462;protein localization to organelle#GO:0033365;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;Golgi apparatus#GO:0005794;late endosome#GO:0005770;endomembrane system#GO:0012505;plasma membrane#GO:0005886;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944 membrane traffic protein#PC00150 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>INSR IGF-R IRR#P00885;Apoptosis signaling pathway#P00006>IGFR2#P00282;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>INSR IGF-R IRR#P00895 IXOSC|EnsemblGenome=LOC121047769|UniProtKB=A0ACM8FGT4 A0ACM8FGT4 LOC121047769 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121834217|UniProtKB=A0ACM8FPR5 A0ACM8FPR5 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042980|UniProtKB=A0ACM8EDS0 A0ACM8EDS0 PTHR13170:SF16 O-GLCNACASE PROTEIN O-GLCNACASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115322171|UniProtKB=A0ACM8EH60 A0ACM8EH60 LOC115322171 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8043222|UniProtKB=A0ACM8F347 A0ACM8F347 LOC8043222 PTHR23019:SF3 NUCLEAR PORE MEMBRANE GLYCOPROTEIN GP210-RELATED NUCLEAR PORE MEMBRANE GLYCOPROTEIN 210 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 transporter#PC00227 IXOSC|EnsemblGenome=LOC8025607|UniProtKB=A0ACM8DJC5 A0ACM8DJC5 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8041441|UniProtKB=A0ACM8ET53 A0ACM8ET53 LOC8041441 PTHR11986:SF126 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transaminase#PC00216 IXOSC|EnsemblGenome=LOC115324562|UniProtKB=A0ACM8F4Q6 A0ACM8F4Q6 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120844020|UniProtKB=A0ACM8EX85 A0ACM8EX85 LOC120844020 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325396|UniProtKB=A0ACM8F7E0 A0ACM8F7E0 LOC115325396 PTHR39299:SF1 TRANSMEMBRANE PROTEIN DUF7789 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050688|UniProtKB=A0ACM8ER37 A0ACM8ER37 LOC8050688 PTHR47537:SF5 CUBILIN CUB DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC120838579|UniProtKB=A0ACM8EK36 A0ACM8EK36 PTHR47333:SF8 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN FIBULIN-5 IXOSC|EnsemblGenome=LOC115310489|UniProtKB=A0ACM8DPT5 A0ACM8DPT5 Ubc7 PTHR24067:SF154 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 G2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 catabolic process#GO:0009056;response to stimulus#GO:0050896;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;response to endoplasmic reticulum stress#GO:0034976;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein K48-linked ubiquitination#GO:0070936;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>Ubc7#P01220 IXOSC|EnsemblGenome=LOC121837567|UniProtKB=A0ACM8G509 A0ACM8G509 LOC121837567 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120836032|UniProtKB=A0ACM8F411 A0ACM8F411 LOC120836032 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8037160|UniProtKB=A0ACM8EPC1 A0ACM8EPC1 LOC8037160 PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED IXOSC|EnsemblGenome=LOC121833989|UniProtKB=A0ACM8FNV0 A0ACM8FNV0 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038284|UniProtKB=A0ACM8E1Q8 A0ACM8E1Q8 Calx PTHR11878:SF80 SODIUM/CALCIUM EXCHANGER SODIUM_CALCIUM EXCHANGER CALX calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;metal ion transport#GO:0030001;export from cell#GO:0140352;homeostatic process#GO:0042592;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121835182|UniProtKB=A0ACM8FSS9 A0ACM8FSS9 LOC121835182 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042401|UniProtKB=A0ACM8F1P3 A0ACM8F1P3 LOC8042401 PTHR16284:SF13 PROTEIN CDV3 HOMOLOG PROTEIN CDV3 HOMOLOG cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115321999|UniProtKB=A0ACM8EG32 A0ACM8EG32 LOC115321999 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC115316660|UniProtKB=A0ACM8EX56 A0ACM8EX56 LOC115316660 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120848926|UniProtKB=A0ACM8G3L4 A0ACM8G3L4 LOC120848926 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8043252|UniProtKB=A0ACM8DL27 A0ACM8DL27 Vps60 PTHR22761:SF12 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 5 intracellular transport#GO:0046907;vacuolar transport#GO:0007034;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;nucleus organization#GO:0006997;endosomal transport#GO:0016197;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;vesicle organization#GO:0016050;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nuclear membrane organization#GO:0071763;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;localization#GO:0051179;cellular localization#GO:0051641;cellular component organization#GO:0016043;membrane assembly#GO:0071709;late endosome to vacuole transport#GO:0045324 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;late endosome#GO:0005770;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8054033|UniProtKB=A0ACM8ENR1 A0ACM8ENR1 LOC8054033 PTHR18952:SF283 CARBONIC ANHYDRASE CARBONIC ANHYDRASE XB-RELATED dehydratase#PC00091;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115329393|UniProtKB=A0ACM8F5H5 A0ACM8F5H5 LOC115329393 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8044018|UniProtKB=A0ACM8FDW4 A0ACM8FDW4 mIF2 PTHR43381:SF20 TRANSLATION INITIATION FACTOR IF-2-RELATED TRANSLATION INITIATION FACTOR IF-2, MITOCHONDRIAL translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;biosynthetic process#GO:0009058 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120847674|UniProtKB=A0ACM8G531 A0ACM8G531 LOC120847674 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8042782|UniProtKB=A0ACM8DPC8 A0ACM8DPC8 Smu1 PTHR22848:SF0 WD40 REPEAT PROTEIN WD40 REPEAT-CONTAINING PROTEIN SMU1 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011 IXOSC|EnsemblGenome=LOC8030110|UniProtKB=A0ACM8DJ90 A0ACM8DJ90 LOC8030110 PTHR13403:SF6 SNURPORTIN1 RNUT1 PROTEIN RNA, U TRANSPORTER 1 SNURPORTIN-1 transporter#PC00227 IXOSC|EnsemblGenome=LOC121836738|UniProtKB=A0ACM8G1I3 A0ACM8G1I3 LOC121836738 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120837151|UniProtKB=A0ACM8EHE2 A0ACM8EHE2 LOC120837151 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120844206|UniProtKB=A0ACM8EY51 A0ACM8EY51 LOC120844206 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115318252|UniProtKB=A0ACM8DXR0 A0ACM8DXR0 LOC115318252 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115316400|UniProtKB=A0ACM8DVY4 A0ACM8DVY4 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035974|UniProtKB=A0ACM8ECY0 A0ACM8ECY0 LOC8035974 PTHR48190:SF2 PROGRAMMED CELL DEATH PROTEIN 7 PROGRAMMED CELL DEATH PROTEIN 7 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 IXOSC|EnsemblGenome=LOC8037628|UniProtKB=A0ACM8F432 A0ACM8F432 LOC8037628 PTHR16295:SF10 TRAF-TYPE ZINC FINGER PROTEIN-RELATED EXPRESSED PROTEIN intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC8037639|UniProtKB=A0ACM8FSX9 A0ACM8FSX9 LOC8037639 PTHR10681:SF163 THIOREDOXIN PEROXIDASE PEROXIREDOXIN 2-RELATED catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;response to oxidative stress#GO:0006979;cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;response to stress#GO:0006950;cellular process#GO:0009987;response to stimulus#GO:0050896;catabolic process#GO:0009056;hydrogen peroxide metabolic process#GO:0042743;homeostatic process#GO:0042592 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 peroxidase#PC00180;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8039853|UniProtKB=A0ACM8E5L3 A0ACM8E5L3 LOC8039853 PTHR11819:SF195 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120842378|UniProtKB=A0ACM8EUR4 A0ACM8EUR4 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042233|UniProtKB=A0ACM8E9V3 A0ACM8E9V3 LOC8042233 PTHR24356:SF450 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TRICORNERED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;establishment or maintenance of cell polarity#GO:0007163 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8052083|UniProtKB=A0ACM8FB70 A0ACM8FB70 PTHR32179:SF3 NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;oxoacid metabolic process#GO:0043436;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;nicotinamide nucleotide metabolic process#GO:0046496;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 IXOSC|EnsemblGenome=LOC115328030|UniProtKB=A0ACM8EEZ8 A0ACM8EEZ8 Sec20 PTHR12825:SF0 BNIP1-RELATED VESICLE TRANSPORT PROTEIN SEC20 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;SNAP receptor activity#GO:0005484 transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane protein complex#GO:0098796;membrane#GO:0016020;organelle#GO:0043226;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8035281|UniProtKB=A0ACM8EFN8 A0ACM8EFN8 LOC8035281 PTHR23118:SF42 ATP-CITRATE SYNTHASE ATP-CITRATE SYNTHASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;carboxylic acid biosynthetic process#GO:0046394;nucleoside phosphate biosynthetic process#GO:1901293;monocarboxylic acid biosynthetic process#GO:0072330;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 transferase#PC00220 Pyruvate metabolism#P02772>Citrate Lyase#P03137 IXOSC|EnsemblGenome=LOC8039200|UniProtKB=A0ACM8E2C0 A0ACM8E2C0 LOC8039200 PTHR10063:SF0 TUBERIN TUBERIN enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;positive regulation of macroautophagy#GO:0016239;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of macroautophagy#GO:0016241;negative regulation of TORC1 signaling#GO:1904262;intracellular signaling cassette#GO:0141124;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of autophagy#GO:0010508;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;cellular response to stimulus#GO:0051716;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432;positive regulation of catabolic process#GO:0009896;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 G-protein modulator#PC00022;GTPase-activating protein#PC00257 p53 pathway by glucose deprivation#P04397>TSC2#P04644;p53 pathway by glucose deprivation#P04397>TSC2#G04706;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>TSC2#P04494 IXOSC|EnsemblGenome=LOC8027422|UniProtKB=A0ACM8DYR5 A0ACM8DYR5 MTA1-like PTHR10865:SF29 METASTASIS-ASSOCIATED PROTEIN AND MESODERM INDUCTION EARLY RESPONSE PROTEIN METASTASIS-ASSOCIATED PROTEIN MTA3 histone deacetylase binding#GO:0042826;transcription coactivator activity#GO:0003713;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;protein binding#GO:0005515;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 p53 pathway#P00059>MTA2#P04615 IXOSC|EnsemblGenome=LOC121835888|UniProtKB=A0ACM8FVK3 A0ACM8FVK3 LOC121835888 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841883|UniProtKB=A0ACM8FUX4 A0ACM8FUX4 LOC120841883 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8023352|UniProtKB=A0ACM8DGU7 A0ACM8DGU7 LOC8023352 PTHR13710:SF152 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q5 macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromosome#GO:0005694 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC115309253|UniProtKB=A0ACM8FCH6 A0ACM8FCH6 LOC115309253 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8051735|UniProtKB=A0ACM8FC95 A0ACM8FC95 LOC8051735 PTHR43763:SF6 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 1 protease#PC00190 IXOSC|EnsemblGenome=LOC120836076|UniProtKB=A0ACM8ELC5 A0ACM8ELC5 PTHR10129:SF50 TRANSCRIPTION FACTOR MAF TRAFFIC JAM, ISOFORM C sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120838161|UniProtKB=A0ACM8EJA1 A0ACM8EJA1 LOC120838161 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8036799|UniProtKB=A0ACM8DJY3 A0ACM8DJY3 Smug PTHR13235:SF2 SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE SINGLE-STRAND SELECTIVE MONOFUNCTIONAL URACIL DNA GLYCOSYLASE DNA N-glycosylase activity#GO:0019104;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;base-excision repair#GO:0006284;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA glycosylase#PC00010 IXOSC|EnsemblGenome=LOC8023316|UniProtKB=A0ACM8E5U0 A0ACM8E5U0 PTHR18911:SF5 CTCL TUMOR ANTIGEN HD-CL-01 COILED-COIL DOMAIN-CONTAINING PROTEIN 186 IXOSC|EnsemblGenome=LOC115329405|UniProtKB=A0ACM8EAY3 A0ACM8EAY3 LOC115329405 PTHR11132:SF521 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E2A-RELATED active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120839730|UniProtKB=A0ACM8FXP4 A0ACM8FXP4 LOC120839730 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8033318|UniProtKB=A0ACM8DWD4 A0ACM8DWD4 Trap1 PTHR11528:SF44 HEAT SHOCK PROTEIN 90 FAMILY MEMBER HEAT SHOCK PROTEIN 75 KDA, MITOCHONDRIAL-RELATED purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP binding#GO:0005524;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;ATP-dependent activity#GO:0140657;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 Hsp90 family chaperone#PC00028;chaperone#PC00072 IXOSC|EnsemblGenome=LOC8029686|UniProtKB=A0ACM8EE81 A0ACM8EE81 wcy PTHR15911:SF6 WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL WW DOMAIN-CONTAINING ADAPTER PROTEIN WITH COILED-COIL chromatin binding#GO:0003682;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 positive regulation of signal transduction#GO:0009967;regulation of autophagy#GO:0010506;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;positive regulation of TORC1 signaling#GO:1904263;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of TOR signaling#GO:0032006;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;regulation of catabolic process#GO:0009894 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8029065|UniProtKB=A0ACM8ED27 A0ACM8ED27 LOC8029065 PTHR42735:SF6 FAMILY NOT NAMED SPHINGOSINE-1-PHOSPHATE LYASE 1 carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829 metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115327367|UniProtKB=A0ACM8FID8 A0ACM8FID8 LOC115327367 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034727|UniProtKB=A0ACM8DYQ4 A0ACM8DYQ4 LOC8034727 PTHR11644:SF2 CYTIDINE DEAMINASE CYTIDINE DEAMINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 nucleobase-containing small molecule catabolic process#GO:0034656;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleoside catabolic process#GO:0009164;nucleobase-containing compound catabolic process#GO:0034655;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;small molecule biosynthetic process#GO:0044283;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 deaminase#PC00088 Pyrimidine Metabolism#P02771>Cytidine Deaminase#P03130;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144 IXOSC|EnsemblGenome=LOC8026786|UniProtKB=A0ACM8DXK1 A0ACM8DXK1 LOC8026786 PTHR47958:SF215 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;helicase activity#GO:0004386 macromolecule metabolic process#GO:0043170;alternative mRNA splicing, via spliceosome#GO:0000380;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8038180|UniProtKB=A0ACM8FKW9 A0ACM8FKW9 LOC8038180 PTHR22552:SF25 GEO11429P1 GEO11429P1-RELATED IXOSC|EnsemblGenome=LOC8052899|UniProtKB=A0ACM8FET3 A0ACM8FET3 LOC8052899 PTHR24208:SF128 LIM/HOMEOBOX PROTEIN LHX LIM3, ISOFORM G sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8051298|UniProtKB=A0ACM8G3S9 A0ACM8G3S9 LOC8051298 PTHR45627:SF26 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 1 cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide metabolic process#GO:0009259;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;signaling#GO:0023052;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cyclic purine nucleotide metabolic process#GO:0052652;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;CCKR signaling map#P06959>Adenylate cyclase#P07127;Gonadotropin-releasing hormone receptor pathway#P06664>AC#P06699;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760 IXOSC|EnsemblGenome=LOC115313024|UniProtKB=A0ACM8FZJ9 A0ACM8FZJ9 LOC115313024 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC8034307|UniProtKB=A0ACM8G1L3 A0ACM8G1L3 LOC8034307 PTHR45981:SF11 LD02310P LD02310P catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;signaling receptor binding#GO:0005102;binding#GO:0005488;acyltransferase activity#GO:0016746;MHC protein binding#GO:0042287;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;immune response#GO:0006955;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;antigen processing and presentation#GO:0019882;immune system process#GO:0002376;protein modification by small protein conjugation or removal#GO:0070647;response to stimulus#GO:0050896;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;late endosome#GO:0005770;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;early endosome membrane#GO:0031901;late endosome membrane#GO:0031902 IXOSC|EnsemblGenome=LOC121834245|UniProtKB=A0ACM8FPU8 A0ACM8FPU8 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833115|UniProtKB=A0ACM8FIA5 A0ACM8FIA5 LOC121833115 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051372|UniProtKB=A0ACM8DQA1 A0ACM8DQA1 LOC8051372 PTHR10472:SF5 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 1 catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;deacylase activity#GO:0160215 tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115317415|UniProtKB=A0ACM8DXL9 A0ACM8DXL9 LOC115317415 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8043788|UniProtKB=A0ACM8DGY5 A0ACM8DGY5 LOC8043788 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8023722|UniProtKB=A0ACM8E1Q4 A0ACM8E1Q4 LOC8023722 PTHR12286:SF5 SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238 intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115308245|UniProtKB=A0ACM8EMQ7 A0ACM8EMQ7 LOC115308245 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8040022|UniProtKB=A0ACM8E3D3 A0ACM8E3D3 PTHR23295:SF6 NUCLEAR RECEPTOR COACTIVATOR 5-RELATED NEOSIN, ISOFORM A transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC115323694|UniProtKB=A0ACM8E368 A0ACM8E368 LOC115323694 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein refolding#GO:0042026;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC8027144|UniProtKB=A0ACM8FJ63 A0ACM8FJ63 LOC8027144 PTHR22730:SF1 PROMININ PROM PROTEIN PROMININ-LIKE PROTEIN cellular process#GO:0009987;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component organization or biogenesis#GO:0071840 plasma membrane region#GO:0098590;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;apical plasma membrane#GO:0016324;microvillus#GO:0005902;actin-based cell projection#GO:0098858;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cilium#GO:0005929 IXOSC|EnsemblGenome=LOC8031778|UniProtKB=A0ACM8E1I3 A0ACM8E1I3 mge PTHR12504:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM22 HOMOLOG protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594 cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrial outer membrane translocase complex#GO:0005742;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8026039|UniProtKB=A0ACM8FJ08 A0ACM8FJ08 LOC8026039 PTHR21136:SF221 SNARE PROTEINS VESICLE-ASSOCIATED MEMBRANE PROTEIN 9 SNAP receptor activity#GO:0005484;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular component organization#GO:0016043;membrane organization#GO:0061024;vesicle fusion#GO:0006906;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;transport#GO:0006810;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234 vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 SNARE protein#PC00034;membrane traffic protein#PC00150 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072 IXOSC|EnsemblGenome=LOC121837350|UniProtKB=A0ACM8G2W6 A0ACM8G2W6 LOC121837350 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8024035|UniProtKB=A0ACM8FU00 A0ACM8FU00 LOC8024035 PTHR11640:SF155 NEPHRIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC121834284|UniProtKB=A0ACM8FPG8 A0ACM8FPG8 PTHR12053:SF4 PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED CARBOXYPEPTIDASE Q catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;peptide catabolic process#GO:0043171;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115328232|UniProtKB=A0ACM8G7J2 A0ACM8G7J2 Oseg5 PTHR24098:SF0 OUTER SEGMENT 5 OUTER SEGMENT 5 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intraciliary transport particle B#GO:0030992;cilium#GO:0005929;intraciliary transport particle#GO:0030990;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8052738|UniProtKB=A0ACM8DTP1 A0ACM8DTP1 LOC8052738 PTHR11183:SF204 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN GLUCOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8030880|UniProtKB=A0ACM8E8S1 A0ACM8E8S1 LOC8030880 PTHR19269:SF45 TROPOMYOSIN TROPOMYOSIN-1, ISOFORMS 33_34 actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component organization#GO:0016043;muscle system process#GO:0003012;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;muscle contraction#GO:0006936;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;system process#GO:0003008;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015 supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 IXOSC|EnsemblGenome=LOC120843123|UniProtKB=A0ACM8EV66 A0ACM8EV66 B4 PTHR14454:SF11 GRB2-ASSOCIATED AND REGULATOR OF MAPK PROTEIN FAMILY MEMBER SERRANO, ISOFORM F IXOSC|EnsemblGenome=LOC121838246|UniProtKB=A0ACM8G8L0 A0ACM8G8L0 LOC121838246 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8035073|UniProtKB=A0ACM8E8A3 A0ACM8E8A3 LOC8035073 PTHR11346:SF191 GALECTIN GALECTIN carbohydrate binding#GO:0030246;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8039410|UniProtKB=A0ACM8G296 A0ACM8G296 VAChT PTHR23506:SF13 GH10249P VESICULAR ACETYLCHOLINE TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;anterograde trans-synaptic signaling#GO:0098916;cellular process#GO:0009987;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 neuron projection#GO:0043005;presynapse#GO:0098793;vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated endocytic vesicle#GO:0045334;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;cell projection#GO:0042995;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;coated membrane#GO:0048475;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;axon terminus#GO:0043679;organelle membrane#GO:0031090;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;neuron projection terminus#GO:0044306;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;intracellular membrane-bounded organelle#GO:0043231;distal axon#GO:0150034;AP-1 adaptor complex#GO:0030121;axon#GO:0030424;trans-Golgi network transport vesicle#GO:0030140;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117 secondary carrier transporter#PC00258;transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>VAChT#P01065;Nicotinic acetylcholine receptor signaling pathway#P00044>VAChT#P01089;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>VAChT#P01078 IXOSC|EnsemblGenome=LOC121833801|UniProtKB=A0ACM8FN60 A0ACM8FN60 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120847418|UniProtKB=A0ACM8G7P0 A0ACM8G7P0 LOC120847418 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031044|UniProtKB=A0ACM8DMI5 A0ACM8DMI5 LOC8031044 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8037288|UniProtKB=A0ACM8DK29 A0ACM8DK29 LOC8037288 PTHR12416:SF3 RRNA-PROCESSING PROTEIN UTP23 HOMOLOG RRNA-PROCESSING PROTEIN UTP23 HOMOLOG binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC120845970|UniProtKB=A0ACM8F0X1 A0ACM8F0X1 LOC120845970 PTHR13191:SF0 RIBOSOMAL RNA PROCESSING PROTEIN 7-RELATED RIBOSOMAL RNA-PROCESSING PROTEIN 7 HOMOLOG A-RELATED cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;ribonucleoprotein complex biogenesis#GO:0022613;ribosome assembly#GO:0042255;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal small subunit assembly#GO:0000028 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;90S preribosome#GO:0030686;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8039910|UniProtKB=A0ACM8G485 A0ACM8G485 LOC8039910 PTHR10159:SF533 DUAL SPECIFICITY PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE VHP-1 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725 regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of cellular process#GO:0048523;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 IXOSC|EnsemblGenome=LOC8034745|UniProtKB=A0ACM8DPM1 A0ACM8DPM1 LOC8034745 PTHR23079:SF55 RNA-DEPENDENT RNA POLYMERASE RNA-DIRECTED RNA POLYMERASE catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;siRNA processing#GO:0030422;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;RNA polymerase complex#GO:0030880 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8031257|UniProtKB=A0ACM8EE71 A0ACM8EE71 LOC8031257 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8036798|UniProtKB=A0ACM8DYQ1 A0ACM8DYQ1 LOC8036798 PTHR48026:SF14 HOMOLOGOUS TO DROSOPHILA SQD (SQUID) PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA processing factor#PC00147;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8043122|UniProtKB=A0ACM8E0H8 A0ACM8E0H8 LOC8043122 PTHR16441:SF10 FIDIPIDINE COILED-COIL DOMAIN-CONTAINING PROTEIN 93 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular transport#GO:0046907;localization within membrane#GO:0051668;transport#GO:0006810;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8037285|UniProtKB=A0ACM8E0G3 A0ACM8E0G3 LOC8037285 PTHR23161:SF2 PROTEIN CIP2A PROTEIN CIP2A protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;organelle organization#GO:0006996;cellular component organization#GO:0016043;response to stress#GO:0006950;response to stimulus#GO:0050896 cytosol#GO:0005829;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8028265|UniProtKB=A0ACM8FJE5 A0ACM8FJE5 LOC8028265 PTHR11690:SF248 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8030767|UniProtKB=A0ACM8DHH2 A0ACM8DHH2 RpL8 PTHR13691:SF16 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121836477|UniProtKB=A0ACM8FZS1 A0ACM8FZS1 LOC121836477 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121048213|UniProtKB=A0ACM8FIU5 A0ACM8FIU5 LOC121048213 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115314117|UniProtKB=A0ACM8DTT1 A0ACM8DTT1 Crag PTHR12296:SF30 DENN DOMAIN-CONTAINING PROTEIN 4 DENN DOMAIN-CONTAINING PROTEIN CRAG nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8037010|UniProtKB=A0ACM8DWU2 A0ACM8DWU2 Diap2 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 enzyme regulator activity#GO:0030234;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;transferase activity#GO:0016740 negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of protein ubiquitination#GO:0031398;regulation of protein ubiquitination#GO:0031396;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of cell cycle#GO:0051726;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115319400|UniProtKB=A0ACM8DZR1 A0ACM8DZR1 LOC115319400 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836697|UniProtKB=A0ACM8G0M5 A0ACM8G0M5 LOC121836697 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8032577|UniProtKB=A0ACM8DRS9 A0ACM8DRS9 LOC8032577 PTHR15660:SF2 BRISC AND BRCA1-A COMPLEX MEMBER 1 BRISC AND BRCA1-A COMPLEX MEMBER 1 macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;negative regulation of cell cycle G2/M phase transition#GO:1902750;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;cell cycle process#GO:0022402 organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC115313879|UniProtKB=A0ACM8FQK1 A0ACM8FQK1 LOC120844053 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8037841|UniProtKB=A0ACM8EUX1 A0ACM8EUX1 LOC8037841 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115317498|UniProtKB=A0ACM8DX89 A0ACM8DX89 LOC115317498 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121836613|UniProtKB=A0ACM8FZF8 A0ACM8FZF8 LOC121836613 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8040588|UniProtKB=A0ACM8E498 A0ACM8E498 LOC8040588 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120847682|UniProtKB=A0ACM8F4C3 A0ACM8F4C3 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8034364|UniProtKB=A0ACM8DJ88 A0ACM8DJ88 PTHR10953:SF9 UBIQUITIN-ACTIVATING ENZYME E1 UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME 5 ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;ubiquitin-like modifier activating enzyme activity#GO:0008641;transferase activity, transferring phosphorus-containing groups#GO:0016772;ligase activity#GO:0016874;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115321362|UniProtKB=A0ACM8F3Z5 A0ACM8F3Z5 LOC115321362 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;monoatomic cation transmembrane transporter activity#GO:0008324 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8040272|UniProtKB=A0ACM8EIT2 A0ACM8EIT2 LOC8040272 PTHR24251:SF57 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120836245|UniProtKB=A0ACM8EUX6 A0ACM8EUX6 LOC120836245 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120838808|UniProtKB=A0ACM8EKQ1 A0ACM8EKQ1 LOC120838808 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033433|UniProtKB=A0ACM8FE98 A0ACM8FE98 dachs PTHR13140:SF498 MYOSIN DACHS, ISOFORM E macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microfilament motor activity#GO:0000146;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;membrane#GO:0016020;actin cytoskeleton#GO:0015629;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC8028487|UniProtKB=A0ACM8E0H2 A0ACM8E0H2 LOC8028487 PTHR11452:SF95 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120836791|UniProtKB=A0ACM8EFV5 A0ACM8EFV5 LOC120836791 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121047924|UniProtKB=A0ACM8FFU6 A0ACM8FFU6 LOC121047924 PTHR24333:SF19 HOMEO BOX HB9 LIKE A-RELATED BRAIN-SPECIFIC HOMEOBOX PROTEIN HOMOLOG homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8039290|UniProtKB=A0ACM8DK99 A0ACM8DK99 LOC8039290 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121834416|UniProtKB=A0ACM8FPL9 A0ACM8FPL9 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838733|UniProtKB=A0ACM8EKD0 A0ACM8EKD0 LOC120838733 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED RH69884P membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8037167|UniProtKB=A0ACM8DHX6 A0ACM8DHX6 LOC8037167 PTHR34766:SF1 UPF0449 PROTEIN C19ORF25 UPF0449 PROTEIN C19ORF25 cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 IXOSC|EnsemblGenome=LOC8053401|UniProtKB=A0ACM8DSV5 A0ACM8DSV5 LOC8053401 PTHR10257:SF5 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B WIDERBORST, ISOFORM H protein phosphatase regulator activity#GO:0019888;phosphatase activator activity#GO:0019211;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;cellular component organization or biogenesis#GO:0071840;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;sister chromatid cohesion#GO:0007062;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;cell cycle#GO:0007049;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 IXOSC|EnsemblGenome=LOC121837259|UniProtKB=A0ACM8G4A9 A0ACM8G4A9 LOC121837259 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838241|UniProtKB=A0ACM8G779 A0ACM8G779 LOC121838241 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8053620|UniProtKB=A0ACM8E2U5 A0ACM8E2U5 Orc3 PTHR12748:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 ORIGIN RECOGNITION COMPLEX SUBUNIT 3 DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA replication origin binding#GO:0003688 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA replication initiation#GO:0006270;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;nuclear pre-replicative complex#GO:0005656;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;nuclear origin of replication recognition complex#GO:0005664;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;DNA replication preinitiation complex#GO:0031261;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;pre-replicative complex#GO:0036387;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 IXOSC|EnsemblGenome=LOC8053933|UniProtKB=A0ACM8E0C1 A0ACM8E0C1 LOC8053933 PTHR10131:SF166 TNF RECEPTOR ASSOCIATED FACTOR RING FINGER PROTEIN 151 signaling adaptor activity#GO:0035591;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8038641|UniProtKB=A0ACM8FX20 A0ACM8FX20 LOC8038641 PTHR23182:SF1 BREAKPOINT CLUSTER REGION PROTEIN BCR RHO GTPASE ACTIVATING PROTEIN AT 1A, ISOFORM E enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of Rho protein signal transduction#GO:0035023;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 postsynaptic density#GO:0014069;cell junction#GO:0030054;membrane#GO:0016020;postsynapse#GO:0098794;cell periphery#GO:0071944;postsynaptic specialization#GO:0099572;organelle#GO:0043226;asymmetric synapse#GO:0032279;neuron to neuron synapse#GO:0098984;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202;plasma membrane#GO:0005886 G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC120847354|UniProtKB=A0ACM8F315 A0ACM8F315 LOC120847354 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8036542|UniProtKB=A0ACM8E7K1 A0ACM8E7K1 LOC8036542 PTHR24410:SF23 HL07962P-RELATED SERINE-ENRICHED PROTEIN defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC115316192|UniProtKB=A0ACM8EJ89 A0ACM8EJ89 LOC115316192 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121835499|UniProtKB=A0ACM8FU95 A0ACM8FU95 LOC121835499 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;response to chemical#GO:0042221;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8023553|UniProtKB=A0ACM8E8T6 A0ACM8E8T6 LOC8023553 PTHR24241:SF190 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CARDIOACCELERATORY PEPTIDE RECEPTOR-LIKE PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120843567|UniProtKB=A0ACM8EWF2 A0ACM8EWF2 LOC120843567 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032569|UniProtKB=A0ACM8E072 A0ACM8E072 LOC8032569 PTHR11785:SF539 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER PROTEIN JHI-21 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;transport#GO:0006810;amino acid transport#GO:0006865;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120841500|UniProtKB=A0ACM8ERD4 A0ACM8ERD4 LOC120841500 PTHR13035:SF0 PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE PROTEIN N-TERMINAL GLUTAMINE AMIDOHYDROLASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120844880|UniProtKB=A0ACM8FZT0 A0ACM8FZT0 LOC120844880 PTHR10166:SF67 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2_DELTA-1-LIKE calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702 voltage-gated ion channel#PC00241;transporter#PC00227 IXOSC|EnsemblGenome=LOC8043038|UniProtKB=A0ACM8DL08 A0ACM8DL08 LOC8043038 PTHR45766:SF6 DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER SNF2 RELATED CHROMATIN REMODELING ANNEALING HELICASE 1 ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013 DNA metabolism protein#PC00009 Wnt signaling pathway#P00057>SWI/SNF#P01435 IXOSC|EnsemblGenome=LOC8033823|UniProtKB=A0ACM8E4E8 A0ACM8E4E8 Sf3b1 PTHR12097:SF0 SPLICING FACTOR 3B, SUBUNIT 1-RELATED SPLICING FACTOR 3B SUBUNIT 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC115318194|UniProtKB=A0ACM8DY85 A0ACM8DY85 Apt1 PTHR10655:SF68 LYSOPHOSPHOLIPASE-RELATED PALMITOYL-PROTEIN HYDROLASE phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;catalytic activity, acting on a protein#GO:0140096;carboxylic ester hydrolase activity#GO:0052689;thiolester hydrolase activity#GO:0016790;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787 regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of transport#GO:0051049;regulation of localization#GO:0032879;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of protein transport#GO:0051224;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;negative regulation of transport#GO:0051051;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of protein localization to membrane#GO:1905475;negative regulation of biological process#GO:0048519 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phospholipase#PC00186;lipase#PC00143 IXOSC|EnsemblGenome=LOC115326803|UniProtKB=A0ACM8EIV4 A0ACM8EIV4 LOC115326803 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120840580|UniProtKB=A0ACM8EPC4 A0ACM8EPC4 LOC120840580 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326005|UniProtKB=A0ACM8EGE4 A0ACM8EGE4 LOC115326005 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120844068|UniProtKB=A0ACM8EXF9 A0ACM8EXF9 LOC120844068 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121838506|UniProtKB=A0ACM8G947 A0ACM8G947 LOC121838506 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8024629|UniProtKB=A0ACM8E7P8 A0ACM8E7P8 Cib2 PTHR45791:SF6 CALCIUM AND INTEGRIN BINDING FAMILY MEMBER 2 CALCIUM AND INTEGRIN-BINDING FAMILY MEMBER 2 calcium ion binding#GO:0005509;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;magnesium ion binding#GO:0000287;metal ion binding#GO:0046872 monoatomic ion homeostasis#GO:0050801;calcium ion homeostasis#GO:0055074;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592 IXOSC|EnsemblGenome=LOC8035806|UniProtKB=A0ACM8DGY1 A0ACM8DGY1 LOC8035806 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575 transferase#PC00220 IXOSC|EnsemblGenome=LOC8025900|UniProtKB=A0ACM8DGQ1 A0ACM8DGQ1 LOC8025900 PTHR11893:SF41 INNEXIN INNEXIN INX2 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell communication#GO:0007154;response to external stimulus#GO:0009605;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;signal transduction#GO:0007165;regulation of biological process#GO:0050789;response to radiation#GO:0009314;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 gap junction#PC00105 IXOSC|EnsemblGenome=LOC120838651|UniProtKB=A0ACM8EK70 A0ACM8EK70 LOC120838651 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8035203|UniProtKB=A0ACM8DJS2 A0ACM8DJS2 Dp1 PTHR10627:SF31 SCP160 DODECA-SATELLITE-BINDING PROTEIN 1, ISOFORM A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120844347|UniProtKB=A0ACM8EY45 A0ACM8EY45 LOC120844347 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 reductase#PC00198 IXOSC|EnsemblGenome=LOC115332108|UniProtKB=A0ACM8F856 A0ACM8F856 LOC115332108 PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 transporter#PC00227 IXOSC|EnsemblGenome=LOC120850362|UniProtKB=A0ACM8F9P7 A0ACM8F9P7 LOC120850362 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120842478|UniProtKB=A0ACM8ETQ7 A0ACM8ETQ7 LOC120842478 PTHR13285:SF26 ACYLTRANSFERASE PROTEIN-CYSTEINE N-PALMITOYLTRANSFERASE RASP acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120844487|UniProtKB=A0ACM8EYG3 A0ACM8EYG3 LOC120844487 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849031|UniProtKB=A0ACM8FP27 A0ACM8FP27 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8033624|UniProtKB=A0ACM8DNZ5 A0ACM8DNZ5 Rrp6 PTHR12124:SF47 POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED EXOSOME COMPLEX COMPONENT 10 IXOSC|EnsemblGenome=LOC8034595|UniProtKB=A0ACM8G106 A0ACM8G106 Usp2 PTHR21646:SF114 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE USP2 deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;regulation of biological quality#GO:0065008;regulation of protein stability#GO:0031647 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8024227|UniProtKB=A0ACM8E252 A0ACM8E252 LOC8024227 PTHR10845:SF192 REGULATOR OF G PROTEIN SIGNALING DOUBLE HIT, ISOFORM B enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789;negative regulation of response to stimulus#GO:0048585;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 GTPase-activating protein#PC00257 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704 IXOSC|EnsemblGenome=LOC121836546|UniProtKB=A0ACM8FYL8 A0ACM8FYL8 LOC121836546 PTHR11439:SF463 GAG-POL-RELATED RETROTRANSPOSON INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120843733|UniProtKB=A0ACM8FZR6 A0ACM8FZR6 LOC120843733 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8037173|UniProtKB=A0ACM8DHY0 A0ACM8DHY0 LOC8037173 PTHR45842:SF12 SYNAPTIC ADHESION-LIKE MOLECULE SALM TIR DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8030957|UniProtKB=A0ACM8DYF1 A0ACM8DYF1 RpA-70 PTHR47165:SF13 OS03G0429900 PROTEIN REPLICATION PROTEIN A 70 KDA DNA-BINDING SUBUNIT IXOSC|EnsemblGenome=LOC8041807|UniProtKB=A0ACM8F628 A0ACM8F628 LOC8041807 PTHR44029:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 DNAJ HOMOLOG SUBFAMILY C MEMBER 21 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115326396|UniProtKB=A0ACM8G0Z7 A0ACM8G0Z7 LOC115326396 PTHR14939:SF5 F-BOX ONLY PROTEIN 22 FIST C-DOMAIN DOMAIN-CONTAINING PROTEIN enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461 IXOSC|EnsemblGenome=LOC8052308|UniProtKB=A0ACM8ETN1 A0ACM8ETN1 LOC8052308 PTHR24543:SF339 MULTICOPPER OXIDASE-RELATED LACTADHERIN-LIKE oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043483|UniProtKB=A0ACM8DL56 A0ACM8DL56 LOC8043483 PTHR45036:SF8 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE-LIKE PROTEIN 7A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC115313960|UniProtKB=A0ACM8DTB1 A0ACM8DTB1 LOC115313960 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121836559|UniProtKB=A0ACM8FZ71 A0ACM8FZ71 LOC121836559 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043267|UniProtKB=A0ACM8DL35 A0ACM8DL35 LOC8043267 PTHR15197:SF0 COILIN P80 COILIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;snRNA binding#GO:0017069 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121836229|UniProtKB=A0ACM8FY25 A0ACM8FY25 LOC121836229 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023118|UniProtKB=A0ACM8E2Y3 A0ACM8E2Y3 LOC8023118 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8030714|UniProtKB=A0ACM8DHF0 A0ACM8DHF0 e(r) PTHR12373:SF0 ENHANCER OF RUDIMENTARY ERH ENHANCER OF RUDIMENTARY HOMOLOG molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 RNA 3'-end processing#GO:0031123;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;regulation of cellular component organization#GO:0051128;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;nuclear mRNA surveillance#GO:0071028;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of chromatin organization#GO:1902275;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8026388|UniProtKB=A0ACM8E4V5 A0ACM8E4V5 vimar PTHR10957:SF1 RAP1 GTPASE-GDP DISSOCIATION STIMULATOR 1 GTPASE-GDP DISSOCIATION STIMULATOR VIMAR cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120849727|UniProtKB=A0ACM8F788 A0ACM8F788 LOC120849727 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024178|UniProtKB=A0ACM8FGP8 A0ACM8FGP8 Oseg4 PTHR12764:SF5 WD REPEAT DOMAIN-RELATED WD REPEAT-CONTAINING PROTEIN 35 IXOSC|EnsemblGenome=LOC120850678|UniProtKB=A0ACM8FAH2 A0ACM8FAH2 LOC120850678 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8025426|UniProtKB=A0ACM8DN55 A0ACM8DN55 Eaf6 PTHR13476:SF0 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 CHROMATIN MODIFICATION-RELATED PROTEIN MEAF6 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC8034355|UniProtKB=A0ACM8DPL7 A0ACM8DPL7 PTHR24366:SF179 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS HATTIFATTENER, ISOFORM I immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8053761|UniProtKB=A0ACM8ECL2 A0ACM8ECL2 CSN3 PTHR10758:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 COP9 SIGNALOSOME COMPLEX SUBUNIT 3 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115321564|UniProtKB=A0ACM8FNT9 A0ACM8FNT9 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8034025|UniProtKB=A0ACM8E696 A0ACM8E696 Sap47 PTHR16019:SF6 SYNAPSE-ASSOCIATED PROTEIN SYNAPSE-ASSOCIATED PROTEIN 1 positive regulation of developmental process#GO:0051094;positive regulation of cell differentiation#GO:0045597;regulation of cell differentiation#GO:0045595;biological regulation#GO:0065007;TOR signaling#GO:0031929;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of fat cell differentiation#GO:0045600;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;signaling#GO:0023052;TORC2 signaling#GO:0038203;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;synapse#GO:0045202;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8026584|UniProtKB=A0ACM8DSQ4 A0ACM8DSQ4 LOC8026584 PTHR45983:SF2 TYROSINE PHOSPHATSE N18, PUTATIVE-RELATED PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8028041|UniProtKB=A0ACM8FHR0 A0ACM8FHR0 LOC8028041 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC120841996|UniProtKB=A0ACM8FMW7 A0ACM8FMW7 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8053790|UniProtKB=A0ACM8EFE9 A0ACM8EFE9 PTHR11616:SF38 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT DOPAMINE TRANSPORTER cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;amino acid transport#GO:0006865;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 Adrenaline and noradrenaline biosynthesis#P00001>DAT#P00065;Parkinson disease#P00049>DAT#P01228;Dopamine receptor mediated signaling pathway#P05912>DAT#P05962;Parkinson disease#P00049>DAT#G01547 IXOSC|EnsemblGenome=LOC8023846|UniProtKB=A0ACM8EMN2 A0ACM8EMN2 LOC8023846 PTHR13071:SF4 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S22 SMALL RIBOSOMAL SUBUNIT PROTEIN MS22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120836492|UniProtKB=A0ACM8EFS9 A0ACM8EFS9 LOC120836492 PTHR44229:SF4 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] CHAIN DEHYDROGENASE_REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02990)-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115328618|UniProtKB=A0ACM8E8F5 A0ACM8E8F5 LOC115328618 PTHR28650:SF1 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS X PROTEIN GPI ALPHA-1,4-MANNOSYLTRANSFERASE I, STABILIZING SUBUNIT IXOSC|EnsemblGenome=LOC8036033|UniProtKB=A0ACM8DH57 A0ACM8DH57 LOC8036033 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8030245|UniProtKB=A0ACM8DGI0 A0ACM8DGI0 LOC8030245 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8041200|UniProtKB=A0ACM8DKK5 A0ACM8DKK5 LOC8041200 PTHR31366:SF2 UPF0739 PROTEIN C1ORF74 UPF0739 PROTEIN C1ORF74 IXOSC|EnsemblGenome=LOC8053252|UniProtKB=A0ACM8E418 A0ACM8E418 LOC8053252 PTHR12385:SF96 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115326460|UniProtKB=A0ACM8E6Y2 A0ACM8E6Y2 LOC115326460 PTHR46830:SF2 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220 IXOSC|EnsemblGenome=LOC8051031|UniProtKB=A0ACM8EL14 A0ACM8EL14 LOC8051031 PTHR21184:SF6 MENORIN (DENDRITIC BRANCHING PROTEIN) MENORIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8038250|UniProtKB=A0ACM8DGT7 A0ACM8DGT7 RpL18 PTHR10934:SF2 60S RIBOSOMAL PROTEIN L18 LARGE RIBOSOMAL SUBUNIT PROTEIN EL18 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115323289|UniProtKB=A0ACM8FVI7 A0ACM8FVI7 LOC115323289 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC120839067|UniProtKB=A0ACM8ELY2 A0ACM8ELY2 LOC120839067 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8054039|UniProtKB=A0ACM8EQH9 A0ACM8EQH9 LOC8054039 PTHR14796:SF3 NEURENSIN 1-RELATED NEURENSIN 1-LIKE-RELATED developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;multicellular organism development#GO:0007275 neuron projection#GO:0043005;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;vesicle#GO:0031982;cell body#GO:0044297;intracellular vesicle#GO:0097708;cell projection#GO:0042995;neuronal cell body#GO:0043025;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 IXOSC|EnsemblGenome=LOC8036096|UniProtKB=A0ACM8EBJ9 A0ACM8EBJ9 LOC8036096 PTHR43437:SF3 HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL-RELATED HYDROXYACYL-THIOESTER DEHYDRATASE TYPE 2, MITOCHONDRIAL catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 dehydratase#PC00091;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120847741|UniProtKB=A0ACM8F4K4 A0ACM8F4K4 LOC120847741 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029160|UniProtKB=A0ACM8FFR7 A0ACM8FFR7 LOC8029160 PTHR10155:SF38 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT SUPPRESSOR OF CYTOKINE SIGNALING AT 36E, ISOFORM D response to chemical#GO:0042221;response to stimulus#GO:0050896;response to cytokine#GO:0034097;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;response to peptide#GO:1901652;cytokine-mediated signaling pathway#GO:0019221;cell surface receptor signaling pathway#GO:0007166 kinase modulator#PC00140 Interferon-gamma signaling pathway#P00035>SOCS#P00956 IXOSC|EnsemblGenome=LOC120850501|UniProtKB=A0ACM8FA42 A0ACM8FA42 LOC120850501 PTHR43161:SF29 SORBITOL DEHYDROGENASE SORBITOL DEHYDROGENASE alcohol dehydrogenase (NAD+) activity#GO:0004022;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;monosaccharide metabolic process#GO:0005996;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate biosynthetic process#GO:0016051;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;hexose biosynthetic process#GO:0019319 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8025829|UniProtKB=A0ACM8EK68 A0ACM8EK68 LOC8025829 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120842573|UniProtKB=A0ACM8EV73 A0ACM8EV73 LOC120842573 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121834635|UniProtKB=A0ACM8FRG3 A0ACM8FRG3 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030662|UniProtKB=A0ACM8DMU8 A0ACM8DMU8 aralar1 PTHR45678:SF9 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED ELECTROGENIC ASPARTATE_GLUTAMATE ANTIPORTER ARALAR, MITOCHONDRIAL carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 establishment of localization#GO:0051234;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;nucleobase-containing compound metabolic process#GO:0006139;dicarboxylic acid transport#GO:0006835;aspartate transmembrane transport#GO:0015810;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;pyridine-containing compound metabolic process#GO:0072524;L-glutamate import#GO:0051938;carboxylic acid transmembrane transport#GO:1905039;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;L-alpha-amino acid transmembrane transport#GO:1902475;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;L-glutamate transmembrane transport#GO:0015813;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;transmembrane transport#GO:0055085;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8029500|UniProtKB=A0ACM8FHH8 A0ACM8FHH8 LOC8029500 PTHR19134:SF527 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 protein phosphatase#PC00195;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8023273|UniProtKB=A0ACM8DGL9 A0ACM8DGL9 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8035926|UniProtKB=A0ACM8E608 A0ACM8E608 LOC8035926 PTHR24305:SF246 CYTOCHROME P450 CYTOCHROME P450 10-LIKE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115329398|UniProtKB=A0ACM8G7Z1 A0ACM8G7Z1 Nubp1 PTHR23264:SF35 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP1 iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC115332121|UniProtKB=A0ACM8ELE8 A0ACM8ELE8 LOC115332121 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8043064|UniProtKB=A0ACM8E7K4 A0ACM8E7K4 PTHR11099:SF0 VACUOLAR SORTING PROTEIN 35 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 35 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 protein localization to cell periphery#GO:1990778;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;retrograde transport, endosome to Golgi#GO:0042147;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;endosome to plasma membrane protein transport#GO:0099638;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;endocytic recycling#GO:0032456;cytosolic transport#GO:0016482 membrane#GO:0016020;cytoplasm#GO:0005737;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vesicle#GO:0031982;retromer complex#GO:0030904;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115308512|UniProtKB=A0ACM8EW33 A0ACM8EW33 LOC115308512 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115313245|UniProtKB=A0ACM8EWT2 A0ACM8EWT2 LOC115313245 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120837490|UniProtKB=A0ACM8EIJ0 A0ACM8EIJ0 LOC120837490 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8026315|UniProtKB=A0ACM8FWC7 A0ACM8FWC7 LOC8026315 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC120851160|UniProtKB=A0ACM8FBF3 A0ACM8FBF3 LOC120851160 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115314225|UniProtKB=A0ACM8DU34 A0ACM8DU34 LOC115314225 PTHR20971:SF0 U6 SNRNA-ASSOCIATED PROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM5 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170 U6 snRNP#GO:0005688;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;Lsm2-8 complex#GO:0120115;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC115308199|UniProtKB=A0ACM8E187 A0ACM8E187 LOC115308199 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378 transferase#PC00220 IXOSC|EnsemblGenome=LOC8030445|UniProtKB=A0ACM8ECA2 A0ACM8ECA2 LOC8030445 PTHR14150:SF12 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 14 UTP14A SMALL SUBUNIT PROCESSOME COMPONENT enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8051452|UniProtKB=A0ACM8DXR7 A0ACM8DXR7 LOC8051452 PTHR24340:SF111 HOMEOBOX PROTEIN NKX TRANSCRIPTION FACTOR PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC121046907|UniProtKB=A0ACM8FM44 A0ACM8FM44 LOC121046907 PTHR24409:SF441 ZINC FINGER PROTEIN 142 TRANSCRIPTIONAL REPRESSOR CTCF DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121834705|UniProtKB=A0ACM8FR44 A0ACM8FR44 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8033544|UniProtKB=A0ACM8DT22 A0ACM8DT22 Upf1 PTHR10887:SF364 DNA2/NAM7 HELICASE FAMILY REGULATOR OF NONSENSE TRANSCRIPTS 1 catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8052384|UniProtKB=A0ACM8EQS7 A0ACM8EQS7 LOC8052384 PTHR13069:SF37 ALKYLATED DNA REPAIR PROTEIN ALKB HOMOLOG 8 FIRE DANCER binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168;RNA binding#GO:0003723;catalytic activity, acting on a tRNA#GO:0140101;tRNA binding#GO:0000049;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8033418|UniProtKB=A0ACM8ETQ9 A0ACM8ETQ9 Ttc26 PTHR14781:SF0 INTRAFLAGELLAR TRANSPORT PROTEIN 56 INTRAFLAGELLAR TRANSPORT PROTEIN 56 binding#GO:0005488;protein-containing complex binding#GO:0044877 cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;intraciliary transport involved in cilium assembly#GO:0035735;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;cellular component organization#GO:0016043;cilium assembly#GO:0060271;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intraciliary transport particle B#GO:0030992;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;intracellular organelle#GO:0043229;intraciliary transport particle#GO:0030990 IXOSC|EnsemblGenome=LOC8052121|UniProtKB=A0ACM8FB95 A0ACM8FB95 Sf3b2 PTHR12785:SF19 SPLICING FACTOR 3B SPLICING FACTOR 3B SUBUNIT 2 nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;cellular anatomical structure#GO:0110165;organelle#GO:0043226;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8035880|UniProtKB=A0ACM8E6Z0 A0ACM8E6Z0 LOC8035880 PTHR21493:SF254 CGI-141-RELATED/LIPASE CONTAINING PROTEIN GOLGI TRANSPORT PROTEIN 1-RELATED intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835464|UniProtKB=A0ACM8FVB1 A0ACM8FVB1 LOC121835464 PTHR45739:SF16 MATRIX PROTEIN, PUTATIVE-RELATED CHONDROITIN SULFATE PROTEOGLYCAN 4 cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;cellular process#GO:0009987;multicellular organismal process#GO:0032501;anatomical structure homeostasis#GO:0060249;epithelial structure maintenance#GO:0010669;homeostatic process#GO:0042592 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8051647|UniProtKB=A0ACM8FI54 A0ACM8FI54 LOC8051647 PTHR43903:SF30 NEUROLIGIN NEUROLIGIN 3, ISOFORM B protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;binding#GO:0005488;signaling receptor binding#GO:0005102 system development#GO:0048731;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;modulation of chemical synaptic transmission#GO:0050804;postsynapse organization#GO:0099173;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;membrane organization#GO:0061024;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic vesicle recycling#GO:0036465;multicellular organismal process#GO:0032501;cellular localization#GO:0051641;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;synapse assembly#GO:0007416;endocytosis#GO:0006897;regulation of biological process#GO:0050789;membrane assembly#GO:0071709;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;nervous system development#GO:0007399;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609 plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane region#GO:0098590;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115315183|UniProtKB=A0ACM8EZX2 A0ACM8EZX2 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC115324814|UniProtKB=A0ACM8E4A9 A0ACM8E4A9 LOC115324814 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312700|UniProtKB=A0ACM8EN84 A0ACM8EN84 LOC115312700 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043443|UniProtKB=A0ACM8DUL9 A0ACM8DUL9 LOC8043443 PTHR12482:SF5 LIPASE ROG1-RELATED-RELATED DUF676 DOMAIN-CONTAINING PROTEIN lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 IXOSC|EnsemblGenome=LOC115314009|UniProtKB=A0ACM8F2F6 A0ACM8F2F6 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;transport#GO:0006810;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;nucleus organization#GO:0006997;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;regulation of metabolic process#GO:0019222;protein localization to nucleus#GO:0034504;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;macromolecule localization#GO:0033036;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;membrane organization#GO:0061024;chromatin organization#GO:0006325;biological regulation#GO:0065007;organelle localization#GO:0051640;localization within membrane#GO:0051668;localization#GO:0051179;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular localization#GO:0051641;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC8036058|UniProtKB=A0ACM8E7Q1 A0ACM8E7Q1 LOC8036058 PTHR16074:SF4 BARDET-BIEDL SYNDROME 7 PROTEIN BBSOME COMPLEX MEMBER BBS7 organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule localization#GO:0033036;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607 cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;neuron projection#GO:0043005;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;BBSome#GO:0034464;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115311097|UniProtKB=A0ACM8FIV6 A0ACM8FIV6 LOC115311097 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8043536|UniProtKB=A0ACM8E5N7 A0ACM8E5N7 LOC8043536 PTHR23119:SF50 DISCS LARGE LAP1 PROTEIN-RELATED protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 cellular localization#GO:0051641;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;intracellular protein localization#GO:0008104;establishment or maintenance of apical/basal cell polarity#GO:0035088;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of bipolar cell polarity#GO:0061245;cell adhesion#GO:0007155;localization within membrane#GO:0051668;receptor clustering#GO:0043113;cell-cell adhesion#GO:0098609;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;cellular process#GO:0009987 cell junction#GO:0030054;cellular anatomical structure#GO:0110165;adherens junction#GO:0005912;anchoring junction#GO:0070161;cell-cell junction#GO:0005911 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8033134|UniProtKB=A0ACM8DHG5 A0ACM8DHG5 LOC8033134 PTHR45842:SF12 SYNAPTIC ADHESION-LIKE MOLECULE SALM TIR DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC121832942|UniProtKB=A0ACM8FNY2 A0ACM8FNY2 LOC121832942 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030387|UniProtKB=A0ACM8E8W3 A0ACM8E8W3 LOC8030387 PTHR10677:SF25 UBIQUILIN UBIQUITIN-LIKE PROTEIN 7 protein binding#GO:0005515;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115309908|UniProtKB=A0ACM8DP32 A0ACM8DP32 LOC115309908 PTHR24264:SF91 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115329878|UniProtKB=A0ACM8EBK1 A0ACM8EBK1 LOC115329878 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835052|UniProtKB=A0ACM8FR94 A0ACM8FR94 LOC121835052 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8052453|UniProtKB=A0ACM8EL06 A0ACM8EL06 LOC8052453 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8032434|UniProtKB=A0ACM8FI11 A0ACM8FI11 LOC8032434 PTHR24083:SF4 NUCLEAR HORMONE RECEPTOR PHOTORECEPTOR-SPECIFIC NUCLEAR RECEPTOR DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115316222|UniProtKB=A0ACM8DVQ4 A0ACM8DVQ4 LOC115316222 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033831|UniProtKB=A0ACM8DYE2 A0ACM8DYE2 LOC8033831 PTHR10151:SF120 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE BIS(5'-ADENOSYL)-TRIPHOSPHATASE catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8024013|UniProtKB=A0ACM8DS91 A0ACM8DS91 LOC8024013 PTHR24377:SF1039 IP01015P-RELATED SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8037847|UniProtKB=A0ACM8DK59 A0ACM8DK59 CNPYb PTHR15382:SF8 CTG4A-RELATED CANOPY B IXOSC|EnsemblGenome=LOC8023425|UniProtKB=A0ACM8EFN7 A0ACM8EFN7 LOC8023425 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8040622|UniProtKB=A0ACM8FF76 A0ACM8FF76 PTHR14187:SF46 ALPHA KINASE/ELONGATION FACTOR 2 KINASE HEAT SHOCK 70 KDA PROTEIN 12A IXOSC|EnsemblGenome=LOC120837283|UniProtKB=A0ACM8EGX8 A0ACM8EGX8 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115328101|UniProtKB=A0ACM8E933 A0ACM8E933 LOC115328101 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8027714|UniProtKB=A0ACM8DV81 A0ACM8DV81 LOC8027714 PTHR21053:SF2 TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL TRANSCRIPTION ELONGATION FACTOR, MITOCHONDRIAL transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;mitochondrial nucleoid#GO:0042645;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoid#GO:0009295;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8053179|UniProtKB=A0ACM8EE25 A0ACM8EE25 LOC8053179 PTHR42735:SF1 FAMILY NOT NAMED PYRIDOXAL-DEPENDENT DECARBOXYLASE DOMAIN-CONTAINING PROTEIN 1-RELATED carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;aldehyde-lyase activity#GO:0016832;lyase activity#GO:0016829 lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;catabolic process#GO:0009056;lipid catabolic process#GO:0016042;cellular process#GO:0009987;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8050836|UniProtKB=A0ACM8FQL2 A0ACM8FQL2 PTHR23055:SF172 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC120847707|UniProtKB=A0ACM8F3P9 A0ACM8F3P9 LOC120847707 PTHR23235:SF164 KRUEPPEL-LIKE TRANSCRIPTION FACTOR CABUT, ISOFORM A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115325828|UniProtKB=A0ACM8F7S2 A0ACM8F7S2 LOC115325828 PTHR47163:SF5 DDE_TNP_IS1595 DOMAIN-CONTAINING PROTEIN ISXO2-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838845|UniProtKB=A0ACM8EK29 A0ACM8EK29 LOC120838845 PTHR22984:SF33 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE 1 catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8052995|UniProtKB=A0ACM8FY38 A0ACM8FY38 bur PTHR11922:SF6 GMP SYNTHASE-RELATED GMP SYNTHASE [GLUTAMINE-HYDROLYZING] ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 ligase#PC00142 De novo purine biosynthesis#P02738>GMP synthase#P02899 IXOSC|EnsemblGenome=LOC115309472|UniProtKB=A0ACM8F587 A0ACM8F587 LOC115309472 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837042|UniProtKB=A0ACM8EG19 A0ACM8EG19 LOC8032620 PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836 synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154 postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC8043555|UniProtKB=A0ACM8DGQ3 A0ACM8DGQ3 LOC8043555 PTHR13563:SF5 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA METHYLTRANSFERASE 10 HOMOLOG C RNA binding#GO:0003723;tRNA binding#GO:0000049;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;mitochondrial gene expression#GO:0140053;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121045550|UniProtKB=A0ACM8FBQ4 A0ACM8FBQ4 LOC121045550 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035799|UniProtKB=A0ACM8DGV4 A0ACM8DGV4 mRpL54 PTHR28595:SF1 39S RIBOSOMAL PROTEIN L54, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML54 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120839082|UniProtKB=A0ACM8EL75 A0ACM8EL75 bai PTHR22811:SF184 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TMED10 PROTEIN membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC121835690|UniProtKB=A0ACM8FW63 A0ACM8FW63 LOC121835690 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121834298|UniProtKB=A0ACM8FPU0 A0ACM8FPU0 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115328525|UniProtKB=A0ACM8EL27 A0ACM8EL27 LOC115328525 PTHR10569:SF2 GLYCOGEN DEBRANCHING ENZYME GLYCOGEN DEBRANCHING ENZYME glucosidase activity#GO:0015926;hydrolase activity#GO:0016787;hexosyltransferase activity#GO:0016758;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;transferase activity#GO:0016740;hydrolase activity, acting on glycosyl bonds#GO:0016798;glycosyltransferase activity#GO:0016757;alpha-glucosidase activity#GO:0090599 cellular process#GO:0009987;glycogen catabolic process#GO:0005980;generation of precursor metabolites and energy#GO:0006091;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;energy derivation by oxidation of organic compounds#GO:0015980;macromolecule metabolic process#GO:0043170;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;glucan catabolic process#GO:0009251;carbohydrate metabolic process#GO:0005975;polysaccharide metabolic process#GO:0005976;catabolic process#GO:0009056;energy reserve metabolic process#GO:0006112;carbohydrate catabolic process#GO:0016052 IXOSC|EnsemblGenome=LOC115322157|UniProtKB=A0ACM8ER36 A0ACM8ER36 LOC115322157 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115328738|UniProtKB=A0ACM8E9M2 A0ACM8E9M2 LOC115328738 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8032803|UniProtKB=A0ACM8EVW7 A0ACM8EVW7 LOC8032803 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364 glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC115327786|UniProtKB=A0ACM8EH81 A0ACM8EH81 LOC115327786 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8028799|UniProtKB=A0ACM8DVE6 A0ACM8DVE6 LOC8028799 PTHR21522:SF70 PROTON CHANNEL OTOP OTOPETRIN-3 proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120848132|UniProtKB=A0ACM8F681 A0ACM8F681 LOC120848132 PTHR46289:SF24 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE IXOSC|EnsemblGenome=LOC121832910|UniProtKB=A0ACM8FPZ5 A0ACM8FPZ5 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838367|UniProtKB=A0ACM8EKM6 A0ACM8EKM6 LOC120838367 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115332876|UniProtKB=A0ACM8EF34 A0ACM8EF34 LOC115332876 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115313473|UniProtKB=A0ACM8EWN3 A0ACM8EWN3 LOC115313473 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8028296|UniProtKB=A0ACM8E471 A0ACM8E471 LOC8028296 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT AT04468P-RELATED molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;ATPase activator activity#GO:0001671 potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;import across plasma membrane#GO:0098739;homeostatic process#GO:0042592;metal ion transport#GO:0030001;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814 plasma membrane protein complex#GO:0098797;cation-transporting ATPase complex#GO:0090533;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8034501|UniProtKB=A0ACM8DSM2 A0ACM8DSM2 STUB1 PTHR46803:SF5 E3 UBIQUITIN-PROTEIN LIGASE CHIP E3 UBIQUITIN-PROTEIN LIGASE CHIP ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;binding#GO:0005488;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein-folding chaperone binding#GO:0051087 macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;cellular response to misfolded protein#GO:0071218;post-translational protein modification#GO:0043687;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to topologically incorrect protein#GO:0035967;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;response to stress#GO:0006950;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of metabolic process#GO:0009893;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of protein metabolic process#GO:0051247;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to stimulus#GO:0050896;response to topologically incorrect protein#GO:0035966;response to misfolded protein#GO:0051788;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446 sarcomere#GO:0030017;myofibril#GO:0030016;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;I band#GO:0031674;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;contractile muscle fiber#GO:0043292;Z disc#GO:0030018 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>CHIP#P01214 IXOSC|EnsemblGenome=LOC8030142|UniProtKB=A0ACM8FX98 A0ACM8FX98 LOC8030142 PTHR15021:SF0 DISCONNECTED-RELATED DISCO-RELATED, ISOFORM A-RELATED regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC121046104|UniProtKB=A0ACM8FD73 A0ACM8FD73 LOC121046104 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314113|UniProtKB=A0ACM8DTS0 A0ACM8DTS0 LOC115314113 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8029034|UniProtKB=A0ACM8DHI8 A0ACM8DHI8 LOC8029034 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043545|UniProtKB=A0ACM8E554 A0ACM8E554 LOC8043545 PTHR13634:SF0 RIBOSOME BIOGENESIS PROTEIN BRIX RIBOSOME BIOGENESIS PROTEIN BRX1 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular component assembly#GO:0022607;ribosomal large subunit assembly#GO:0000027;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;organelle assembly#GO:0070925 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8033637|UniProtKB=A0ACM8ECI3 A0ACM8ECI3 LOC8033637 PTHR11909:SF7 CASEIN KINASE-RELATED CELL DIVISION CYCLE 7-RELATED PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;signal transduction#GO:0007165;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115316210|UniProtKB=A0ACM8EYQ7 A0ACM8EYQ7 LOC115316210 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115322392|UniProtKB=A0ACM8G199 A0ACM8G199 LOC115322392 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036074|UniProtKB=A0ACM8DNA7 A0ACM8DNA7 LOC8036074 PTHR13058:SF19 THREE PRIME REPAIR EXONUCLEASE 1, 2 LD40940P 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;exonuclease activity#GO:0004527 nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115311846|UniProtKB=A0ACM8DRK7 A0ACM8DRK7 LOC115311846 PTHR10459:SF112 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 1 pentosyltransferase activity#GO:0016763;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 IXOSC|EnsemblGenome=LOC121834295|UniProtKB=A0ACM8FNH1 A0ACM8FNH1 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051066|UniProtKB=A0ACM8DNS9 A0ACM8DNS9 LOC8051066 PTHR24026:SF133 FAT ATYPICAL CADHERIN-RELATED CADHERIN-RELATED FAMILY MEMBER 2 system development#GO:0048731;anatomical structure development#GO:0048856;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;tissue development#GO:0009888;multicellular organismal process#GO:0032501;epithelial cell differentiation#GO:0030855;epithelium development#GO:0060429;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 IXOSC|EnsemblGenome=LOC8026265|UniProtKB=A0ACM8G5E8 A0ACM8G5E8 LOC8026265 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793 microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120846756|UniProtKB=A0ACM8F2X2 A0ACM8F2X2 LOC120846756 PTHR13848:SF2 PROTEIN YIPPEE-LIKE CG15309-RELATED PROTEIN YIPPEE-LIKE ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120837227|UniProtKB=A0ACM8EGX7 A0ACM8EGX7 LOC120837227 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318360|UniProtKB=A0ACM8DXT7 A0ACM8DXT7 LOC115318360 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120846432|UniProtKB=A0ACM8F2B9 A0ACM8F2B9 LOC120846432 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120839981|UniProtKB=A0ACM8G5I5 A0ACM8G5I5 LOC120839981 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8036523|UniProtKB=A0ACM8DUX6 A0ACM8DUX6 LOC8036523 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120839078|UniProtKB=A0ACM8EL70 A0ACM8EL70 Vha26 PTHR45715:SF23 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED ATPASE H+ TRANSPORTING V1 SUBUNIT E1 ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;organelle#GO:0043226;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495 IXOSC|EnsemblGenome=LOC120839487|UniProtKB=A0ACM8EM21 A0ACM8EM21 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120841491|UniProtKB=A0ACM8FG54 A0ACM8FG54 LOC120841491 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC8053211|UniProtKB=A0ACM8DM01 A0ACM8DM01 LOC8053211 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052290|UniProtKB=A0ACM8E1Y1 A0ACM8E1Y1 LOC8052290 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8029191|UniProtKB=A0ACM8E3Z6 A0ACM8E3Z6 ATPsyndelta PTHR13822:SF7 ATP SYNTHASE DELTA/EPSILON CHAIN ATP SYNTHASE F(1) COMPLEX SUBUNIT DELTA, MITOCHONDRIAL proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;passive transmembrane transporter activity#GO:0022803;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ATP biosynthetic process#GO:0006754;ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;proton motive force-driven ATP synthesis#GO:0015986;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;membrane#GO:0016020;proton-transporting ATP synthase complex#GO:0045259;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC121047187|UniProtKB=A0ACM8FVU8 A0ACM8FVU8 LOC121047187 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840676|UniProtKB=A0ACM8EQQ0 A0ACM8EQQ0 LOC120840676 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115333215|UniProtKB=A0ACM8EFQ4 A0ACM8EFQ4 LOC115333215 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121837529|UniProtKB=A0ACM8G555 A0ACM8G555 LOC121837529 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037653|UniProtKB=A0ACM8DI71 A0ACM8DI71 LOC8037653 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8053549|UniProtKB=A0ACM8ECZ3 A0ACM8ECZ3 LOC8053549 PTHR15574:SF40 WD REPEAT DOMAIN-CONTAINING FAMILY WD AND TETRATRICOPEPTIDE REPEATS PROTEIN 1 regulation of primary metabolic process#GO:0080090;negative regulation of biological process#GO:0048519;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of lipid biosynthetic process#GO:0046890;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216;regulation of biosynthetic process#GO:0009889 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8023657|UniProtKB=A0ACM8FTT5 A0ACM8FTT5 LOC8023657 PTHR13119:SF12 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEI PROTEIN SUPPRESSOR OF SABLE DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription repressor activity#GO:0001217;transcription regulator activity#GO:0140110;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription elongation#GO:0032784;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8026242|UniProtKB=A0ACM8F7R3 A0ACM8F7R3 LOC8026242 PTHR13856:SF137 VHS DOMAIN CONTAINING PROTEIN FAMILY GH05942P protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell communication#GO:0007154 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8024592|UniProtKB=A0ACM8DIF3 A0ACM8DIF3 Vti1a PTHR21230:SF102 VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A SNAP receptor activity#GO:0005484;protein binding#GO:0005515;molecular adaptor activity#GO:0060090;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488 localization#GO:0051179;Golgi to vacuole transport#GO:0006896;vesicle fusion#GO:0006906;catabolic process#GO:0009056;Golgi organization#GO:0007030;intra-Golgi vesicle-mediated transport#GO:0006891;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907;membrane organization#GO:0061024;macroautophagy#GO:0016236;retrograde transport, endosome to Golgi#GO:0042147;membrane fusion#GO:0061025;post-Golgi vesicle-mediated transport#GO:0006892;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;endosomal transport#GO:0016197;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;metabolic process#GO:0008152;endomembrane system organization#GO:0010256;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;cellular process#GO:0009987;organelle organization#GO:0006996 endoplasmic reticulum#GO:0005783;ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum membrane#GO:0005789;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;transport vesicle#GO:0030133;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 membrane traffic protein#PC00150;SNARE protein#PC00034 Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042 IXOSC|EnsemblGenome=LOC8033228|UniProtKB=A0ACM8EFU3 A0ACM8EFU3 LOC8033228 PTHR23003:SF51 RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN SERINE-ARGININE PROTEIN 55 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC115327660|UniProtKB=A0ACM8E7B1 A0ACM8E7B1 LOC115327660 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC120843875|UniProtKB=A0ACM8EWS4 A0ACM8EWS4 LOC120843875 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027181|UniProtKB=A0ACM8DS16 A0ACM8DS16 LOC8027181 PTHR12103:SF15 5'-NUCLEOTIDASE DOMAIN-CONTAINING 5' NUCLEOTIDASE B, ISOFORM G phosphatase activity#GO:0016791;nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleotide metabolic process#GO:0009150;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117 hydrolase#PC00121;nucleotide phosphatase#PC00173;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC120845781|UniProtKB=A0ACM8F0U1 A0ACM8F0U1 LOC120845781 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120850105|UniProtKB=A0ACM8F904 A0ACM8F904 LOC120850105 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120841913|UniProtKB=A0ACM8ESP1 A0ACM8ESP1 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121835559|UniProtKB=A0ACM8FW07 A0ACM8FW07 LOC121835559 PTHR45883:SF2 HSC70-INTERACTING PROTEIN HSC70-INTERACTING PROTEIN heat shock protein binding#GO:0031072;binding#GO:0005488;protein-folding chaperone binding#GO:0051087;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 IXOSC|EnsemblGenome=LOC115319062|UniProtKB=A0ACM8DZ62 A0ACM8DZ62 LOC115319062 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8024210|UniProtKB=A0ACM8FH46 A0ACM8FH46 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8032495|UniProtKB=A0ACM8DJI9 A0ACM8DJI9 LOC8032495 PTHR46458:SF1 BLR2807 PROTEIN NEUROGLOBIN binding#GO:0005488;small molecule binding#GO:0036094;molecular carrier activity#GO:0140104 response to stimulus#GO:0050896;response to oxygen levels#GO:0070482;response to decreased oxygen levels#GO:0036293;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;localization#GO:0051179;establishment of localization#GO:0051234;response to hypoxia#GO:0001666;transport#GO:0006810 transporter#PC00227 IXOSC|EnsemblGenome=LOC115332840|UniProtKB=A0ACM8FKP6 A0ACM8FKP6 LOC115332840 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8042448|UniProtKB=A0ACM8FQG5 A0ACM8FQG5 LOC8042448 PTHR15635:SF12 COILED-COIL DOMAIN CONTAINING PROTEIN 9 HABP4_PAI-RBP1 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842802|UniProtKB=A0ACM8EUN4 A0ACM8EUN4 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115319288|UniProtKB=A0ACM8DZT4 A0ACM8DZT4 pix PTHR19248:SF32 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY E MEMBER 1 cation binding#GO:0043169;ribonucleoprotein complex binding#GO:0043021;transition metal ion binding#GO:0046914;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleotide binding#GO:0000166;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;metal ion binding#GO:0046872;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;iron ion binding#GO:0005506;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;gene expression#GO:0010467;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex disassembly#GO:0032984;protein biosynthetic process#GO:0160307;translational initiation#GO:0006413;translation#GO:0006412;translational termination#GO:0006415;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120837207|UniProtKB=A0ACM8EHI6 A0ACM8EHI6 LOC120837207 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115309681|UniProtKB=A0ACM8DNX7 A0ACM8DNX7 LOC115309681 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC121835343|UniProtKB=A0ACM8FUM3 A0ACM8FUM3 LOC121835343 PTHR43788:SF20 DNA2/NAM7 HELICASE FAMILY MEMBER DNA-BINDING PROTEIN SMUBP-2 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stress#GO:0006950;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120843538|UniProtKB=A0ACM8EWD3 A0ACM8EWD3 LOC120843538 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834421|UniProtKB=A0ACM8FQ69 A0ACM8FQ69 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043619|UniProtKB=A0ACM8DV55 A0ACM8DV55 Larp4B PTHR22792:SF131 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN LARP4B mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115321449|UniProtKB=A0ACM8E1S4 A0ACM8E1S4 LOC115321449 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023970|UniProtKB=A0ACM8DHT4 A0ACM8DHT4 LOC8023970 PTHR24373:SF406 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TARTAN, ISOFORM B signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120849827|UniProtKB=A0ACM8F7G4 A0ACM8F7G4 LOC120849827 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8041076|UniProtKB=A0ACM8EDT4 A0ACM8EDT4 PTHR45976:SF1 ARMADILLO SEGMENT POLARITY PROTEIN ARMADILLO SEGMENT POLARITY PROTEIN transcription coactivator activity#GO:0003713;protein phosphatase binding#GO:0019903;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;phosphatase binding#GO:0019902;binding#GO:0005488;transcription regulator activity#GO:0140110;enzyme binding#GO:0019899 regulation of DNA-templated transcription#GO:0006355;canonical Wnt signaling pathway#GO:0060070;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;Wnt signaling pathway#GO:0016055;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cell adhesion#GO:0007155;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;cell surface receptor signaling pathway#GO:0007166;positive regulation of macromolecule metabolic process#GO:0010604;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165 membrane#GO:0016020;cell-cell junction#GO:0005911;nucleus#GO:0005634;cell periphery#GO:0071944;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;adherens junction#GO:0005912;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161 p53 pathway feedback loops 2#P04398>beta-catenin#P04670;Cadherin signaling pathway#P00012>betacatenin#P00463;Wnt signaling pathway#P00057>Beta-Catenin#P01432;Angiogenesis#P00005>beta catenin#P00187;Alzheimer disease-presenilin pathway#P00004>beta-catenin#P00156 IXOSC|EnsemblGenome=LOC115330623|UniProtKB=A0ACM8FBG1 A0ACM8FBG1 LOC115330623 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308191|UniProtKB=A0ACM8EIN8 A0ACM8EIN8 LOC8037988 PTHR23049:SF72 MYOSIN REGULATORY LIGHT CHAIN 2 MYOSIN REGULATORY LIGHT CHAIN SQH myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 developmental process#GO:0032502;post-embryonic development#GO:0009791;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120850964|UniProtKB=A0ACM8FC08 A0ACM8FC08 LOC120850964 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;biosynthetic process#GO:0009058;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283 reductase#PC00198 IXOSC|EnsemblGenome=LOC8028539|UniProtKB=A0ACM8E7G1 A0ACM8E7G1 LOC8028539 PTHR14614:SF44 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN N-LYSINE METHYLTRANSFERASE METTL21D catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120846366|UniProtKB=A0ACM8F266 A0ACM8F266 LOC120846366 PTHR12801:SF115 RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED FI18136P1-RELATED exonuclease activity#GO:0004527;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;exoribonuclease#PC00099 DNA replication#P00017>RNase H#P00538 IXOSC|EnsemblGenome=LOC120846051|UniProtKB=A0ACM8FH62 A0ACM8FH62 LOC120846051 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325814|UniProtKB=A0ACM8E568 A0ACM8E568 LOC115325814 PTHR12430:SF0 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20 TRANSLOCASE OF OUTER MITOCHONDRIAL MEMBRANE 20 protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;RNA localization#GO:0006403;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;mitochondrial transport#GO:0006839;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;protein localization to mitochondrion#GO:0070585;transmembrane transport#GO:0055085;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542 membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;mitochondrial outer membrane translocase complex#GO:0005742;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115328380|UniProtKB=A0ACM8E8M4 A0ACM8E8M4 Vps11 PTHR23323:SF24 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 11 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;organelle fusion#GO:0048284;vesicle organization#GO:0016050;endosome organization#GO:0007032;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;vesicle tethering complex#GO:0099023 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8041996|UniProtKB=A0ACM8FVW4 A0ACM8FVW4 LOC8041996 PTHR42923:SF3 PROTOPORPHYRINOGEN OXIDASE PROTOPORPHYRINOGEN OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidase#PC00175;oxidoreductase#PC00176 Heme biosynthesis#P02746>Protoporphyrinogen oxidase#P02976 IXOSC|EnsemblGenome=LOC8043982|UniProtKB=A0ACM8FJ73 A0ACM8FJ73 LOC8043982 PTHR42909:SF1 ZGC:136858 CARBOHYDRATE KINASE PFKB DOMAIN-CONTAINING PROTEIN hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121046063|UniProtKB=A0ACM8FD13 A0ACM8FD13 LOC121046063 PTHR46730:SF1 POLYCYSTIN-1 POLYCYSTIN-1-LIKE PROTEIN 1 ISOFORM X1 passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC115308715|UniProtKB=A0ACM8F7E8 A0ACM8F7E8 LOC115308715 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8030370|UniProtKB=A0ACM8G783 A0ACM8G783 LOC8030370 PTHR37456:SF10 SI:CH211-266K2.1 COLLAGEN ALPHA-1(XXVII) CHAIN-RELATED IXOSC|EnsemblGenome=LOC115321486|UniProtKB=A0ACM8ENZ6 A0ACM8ENZ6 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115325686|UniProtKB=A0ACM8E502 A0ACM8E502 LOC115325686 PTHR10340:SF63 SPHINGOMYELIN PHOSPHODIESTERASE METALLOPHOS DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8033789|UniProtKB=A0ACM8FXQ6 A0ACM8FXQ6 LOC8033789 PTHR12960:SF0 GLE-1-RELATED MRNA EXPORT FACTOR GLE1 phospholipid binding#GO:0005543;alcohol binding#GO:0043178;translation initiation factor binding#GO:0031369;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;lipid binding#GO:0008289;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 translation factor#PC00223 IXOSC|EnsemblGenome=LOC115332621|UniProtKB=A0ACM8F9K5 A0ACM8F9K5 LOC115332621 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8050794|UniProtKB=A0ACM8DXL6 A0ACM8DXL6 LOC8050794 PTHR24174:SF1 ANKYRIN REPEAT AND STERILE ALPHA MOTIF DOMAIN-CONTAINING PROTEIN 1 IP14385P cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115319059|UniProtKB=A0ACM8DYJ1 A0ACM8DYJ1 LOC115319059 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8023381|UniProtKB=A0ACM8F5V4 A0ACM8F5V4 LOC8023381 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC120836166|UniProtKB=A0ACM8EQT7 A0ACM8EQT7 LOC120836166 PTHR45636:SF16 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX POX-MESO PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8029214|UniProtKB=A0ACM8DPC5 A0ACM8DPC5 SdhB PTHR11921:SF47 SUCCINATE DEHYDROGENASE IRON-SULFUR PROTEIN SUCCINATE DEHYDROGENASE [UBIQUINONE] IRON-SULFUR SUBUNIT, MITOCHONDRIAL electron transport chain#GO:0022900;cellular process#GO:0009987;respiratory electron transport chain#GO:0022904;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;membrane#GO:0016020;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115319827|UniProtKB=A0ACM8DZL8 A0ACM8DZL8 PTHR12184:SF1 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 FAMILY MEMBER UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 1 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8051619|UniProtKB=A0ACM8FHX4 A0ACM8FHX4 LOC8051619 PTHR23079:SF55 RNA-DEPENDENT RNA POLYMERASE RNA-DIRECTED RNA POLYMERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 regulation of biological process#GO:0050789;siRNA processing#GO:0030422;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;transferase complex, transferring phosphorus-containing groups#GO:0061695 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8051138|UniProtKB=A0ACM8DNZ2 A0ACM8DNZ2 LOC8051138 PTHR43520:SF35 ATP7, ISOFORM B P-TYPE CU(+) TRANSPORTER cation binding#GO:0043169;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion binding#GO:0046872;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;transition metal ion transmembrane transporter activity#GO:0046915;binding#GO:0005488;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;transporter activity#GO:0005215;copper ion binding#GO:0005507 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;copper ion transmembrane transport#GO:0035434;metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987 membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8025059|UniProtKB=A0ACM8FT78 A0ACM8FT78 vap PTHR10194:SF146 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN 1 GTPase-activating protein#PC00257 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Ras#P00886;EGF receptor signaling pathway#P00018>GAP#P00546;PDGF signaling pathway#P00047>RasGAP#P01152;FGF signaling pathway#P00021>RasGAP#P00646;Interleukin signaling pathway#P00036>RasGAP#P00975;Angiogenesis#P00005>GAP#P00205;Angiogenesis#P00005>RasGAP#P00190 IXOSC|EnsemblGenome=LOC121835437|UniProtKB=A0ACM8FUN1 A0ACM8FUN1 LOC121835437 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320087|UniProtKB=A0ACM8FRF5 A0ACM8FRF5 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8024319|UniProtKB=A0ACM8EVY3 A0ACM8EVY3 LOC8024319 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040172|UniProtKB=A0ACM8FEG1 A0ACM8FEG1 LOC8040172 PTHR45620:SF32 PDF RECEPTOR-LIKE PROTEIN-RELATED DIURETIC HORMONE 31 RECEPTOR, ISOFORM C transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8036185|UniProtKB=A0ACM8DVW4 A0ACM8DVW4 scat PTHR12965:SF0 VACUOLAR PROTEIN SORTING 54 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 54 protein binding#GO:0005515;syntaxin binding#GO:0019905;binding#GO:0005488;SNARE binding#GO:0000149 vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;localization within membrane#GO:0051668 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8025123|UniProtKB=A0ACM8DV06 A0ACM8DV06 Arp2 PTHR11937:SF37 ACTIN ACTIN-RELATED PROTEIN 2 structural molecule activity#GO:0005198;cytoskeletal protein binding#GO:0008092;protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;Arp2/3 complex-mediated actin nucleation#GO:0034314;actin cytoskeleton organization#GO:0030036;actin nucleation#GO:0045010;cytoskeleton organization#GO:0007010 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;Arp2/3 protein complex#GO:0005885;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Cadherin signaling pathway#P00012>F-actin#P00470;Alzheimer disease-presenilin pathway#P00004>actin#P00114;Huntington disease#P00029>Actin#P00807 IXOSC|EnsemblGenome=LOC8025631|UniProtKB=A0ACM8EDB1 A0ACM8EDB1 LOC8025631 PTHR43691:SF11 URIDINE PHOSPHORYLASE FI09636P-RELATED intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 Salvage pyrimidine ribonucleotides#P02775>Uridine phosphorylase#P03152 IXOSC|EnsemblGenome=LOC8025657|UniProtKB=A0ACM8DJG3 A0ACM8DJG3 LOC8025657 PTHR45902:SF2 LATROPHILIN RECEPTOR-LIKE PROTEIN A G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120848756|UniProtKB=A0ACM8F5I1 A0ACM8F5I1 LOC120848756 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115317639|UniProtKB=A0ACM8DXB2 A0ACM8DXB2 LOC115317639 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041680|UniProtKB=A0ACM8DKP4 A0ACM8DKP4 emc PTHR11723:SF17 DNA-BINDING PROTEIN INHIBITOR PROTEIN EXTRA-MACROCHAETAE transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 multicellular organism development#GO:0007275;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;neuron differentiation#GO:0030182;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115308822|UniProtKB=A0ACM8DN16 A0ACM8DN16 LOC115308822 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121833765|UniProtKB=A0ACM8FNR7 A0ACM8FNR7 PTHR47501:SF10 TRANSPOSASE-RELATED DUF659 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115309118|UniProtKB=A0ACM8DNH0 A0ACM8DNH0 LOC115309118 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120843439|UniProtKB=A0ACM8ECE7 A0ACM8ECE7 LOC120843439 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115321271|UniProtKB=A0ACM8E247 A0ACM8E247 LOC115321271 PTHR11929:SF249 ALPHA- 1,3 -FUCOSYLTRANSFERASE FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920;transferase activity#GO:0016740;catalytic activity#GO:0003824;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8043525|UniProtKB=A0ACM8FK99 A0ACM8FK99 LOC8043525 PTHR19432:SF37 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;symporter activity#GO:0015293;solute:proton symporter activity#GO:0015295;carbohydrate transmembrane transporter activity#GO:0015144;monoatomic cation transmembrane transporter activity#GO:0008324 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8039313|UniProtKB=A0ACM8FUY7 A0ACM8FUY7 LOC8039313 PTHR47980:SF29 LD44762P RAS-RELATED PROTEIN RAB-1 secretion by cell#GO:0032940;exocytosis#GO:0006887;establishment of localization#GO:0051234;secretion#GO:0046903;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8042294|UniProtKB=A0ACM8DKW2 A0ACM8DKW2 LOC8042294 PTHR31592:SF1 TRANSMEMBRANE PROTEIN 192 TRANSMEMBRANE PROTEIN 192 endomembrane system#GO:0012505;late endosome#GO:0005770;vacuole#GO:0005773;cytoplasm#GO:0005737;membrane#GO:0016020;lysosomal membrane#GO:0005765;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 IXOSC|EnsemblGenome=LOC8042907|UniProtKB=A0ACM8F835 A0ACM8F835 LOC8042907 PTHR45789:SF6 FI18025P1 FI18025P1 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 cell fate commitment#GO:0045165;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120850186|UniProtKB=A0ACM8F8A4 A0ACM8F8A4 LOC120850186 PTHR23235:SF130 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 367 RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120844392|UniProtKB=A0ACM8EYJ1 A0ACM8EYJ1 LOC120844392 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8043084|UniProtKB=A0ACM8G7M3 A0ACM8G7M3 LOC8043084 PTHR24416:SF550 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1-RELATED transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 positive regulation of MAPK cascade#GO:0043410;response to fibroblast growth factor#GO:0071774;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;fibroblast growth factor receptor signaling pathway#GO:0008543;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of cellular process#GO:0048522;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;cell surface receptor signaling pathway#GO:0007166;regulation of MAPK cascade#GO:0043408;cellular response to fibroblast growth factor stimulus#GO:0044344;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of signaling#GO:0023056;cellular response to growth factor stimulus#GO:0071363;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;positive regulation of cell population proliferation#GO:0008284;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8042050|UniProtKB=A0ACM8E0B8 A0ACM8E0B8 LOC8042050 PTHR23345:SF15 VITELLOGENIN-RELATED VITELLOGENIN-6 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 storage protein#PC00210 IXOSC|EnsemblGenome=LOC8023756|UniProtKB=A0ACM8FJF5 A0ACM8FJF5 LOC8023756 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8023434|UniProtKB=A0ACM8DH19 A0ACM8DH19 LOC8023434 PTHR24113:SF12 RAN GTPASE-ACTIVATING PROTEIN 1 RAN GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme binding#GO:0019899;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234 nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;transport#GO:0006810;intracellular transport#GO:0046907;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115316528|UniProtKB=A0ACM8F2L7 A0ACM8F2L7 LOC115316528 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033109|UniProtKB=A0ACM8DP47 A0ACM8DP47 LOC8033109 PTHR12989:SF10 ALPHA-1,2-GLUCOSYLTRANSFERASE ALG10 DOL-P-GLC:GLC(2)MAN(9)GLCNAC(2)-PP-DOL ALPHA-1,2-GLUCOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 IXOSC|EnsemblGenome=LOC8038202|UniProtKB=A0ACM8EYF6 A0ACM8EYF6 muc PTHR23151:SF94 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522 acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739 transferase#PC00220;acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC120841571|UniProtKB=A0ACM8ERJ8 A0ACM8ERJ8 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024186|UniProtKB=A0ACM8DI02 A0ACM8DI02 LOC8024186 PTHR12463:SF0 OXYGENASE-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 4 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actomyosin structure organization#GO:0031032;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;midbody#GO:0030496;contractile ring#GO:0070938 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120840519|UniProtKB=A0ACM8EPA1 A0ACM8EPA1 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8040242|UniProtKB=A0ACM8E0Y3 A0ACM8E0Y3 Mlc1 PTHR23048:SF33 MYOSIN LIGHT CHAIN 1, 3 MYOSIN LIGHT CHAIN ALKALI cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;contractile muscle fiber#GO:0043292;supramolecular complex#GO:0099080;organelle#GO:0043226;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115327217|UniProtKB=A0ACM8G8M5 A0ACM8G8M5 LOC115327217 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8025486|UniProtKB=A0ACM8DYM0 A0ACM8DYM0 LOC8025486 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115316160|UniProtKB=A0ACM8DVP0 A0ACM8DVP0 LOC115316160 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849198|UniProtKB=A0ACM8F7M6 A0ACM8F7M6 LOC120849198 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120841853|UniProtKB=A0ACM8ETN3 A0ACM8ETN3 LOC120841853 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 establishment of localization#GO:0051234;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;transport#GO:0006810;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;ceramide metabolic process#GO:0006672;localization#GO:0051179;lipid localization#GO:0010876;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8034331|UniProtKB=A0ACM8EAS2 A0ACM8EAS2 LOC8034331 PTHR23235:SF196 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121047753|UniProtKB=A0ACM8G4M2 A0ACM8G4M2 LOC121047753 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115318910|UniProtKB=A0ACM8DZ04 A0ACM8DZ04 Etfb PTHR21294:SF8 ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT BETA lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836441|UniProtKB=A0ACM8FZZ2 A0ACM8FZZ2 LOC121836441 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115316365|UniProtKB=A0ACM8FLI1 A0ACM8FLI1 LOC8031047 PTHR45859:SF1 TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT BETA TRANSLATION INITIATION FACTOR EIF2B SUBUNIT BETA guanyl-nucleotide exchange factor activity#GO:0005085;translation factor activity#GO:0180051;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;translation initiation factor activity#GO:0003743;molecular function regulator activity#GO:0098772 biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152 guanyl-nucleotide exchange factor complex#GO:0032045;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC115329352|UniProtKB=A0ACM8E9E7 A0ACM8E9E7 LOC115329352 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026340|UniProtKB=A0ACM8DMN4 A0ACM8DMN4 Vsp37A PTHR13678:SF2 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 37A protein targeting to vacuole#GO:0006623;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein targeting to membrane#GO:0006612;intracellular protein transport#GO:0006886;protein targeting#GO:0006605;establishment of protein localization to vacuole#GO:0072666;cellular localization#GO:0051641;protein transport#GO:0015031;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;vacuolar transport#GO:0007034;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;localization#GO:0051179;protein localization to vacuole#GO:0072665;localization within membrane#GO:0051668 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;ESCRT I complex#GO:0000813;membrane#GO:0016020;vesicle membrane#GO:0012506 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC121046012|UniProtKB=A0ACM8FCX1 A0ACM8FCX1 LOC121046012 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8043259|UniProtKB=A0ACM8E8H2 A0ACM8E8H2 LOC8043259 PTHR44675:SF1 PAK1 INTERACTING PROTEIN 1 P21-ACTIVATED PROTEIN KINASE-INTERACTING PROTEIN 1 enzyme inhibitor activity#GO:0004857;protein kinase regulator activity#GO:0019887;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase inhibitor activity#GO:0019210;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8033411|UniProtKB=A0ACM8FJ24 A0ACM8FJ24 LOC8033411 PTHR46488:SF1 AP-5 COMPLEX SUBUNIT ZETA-1 AP-5 COMPLEX SUBUNIT ZETA-1 IXOSC|EnsemblGenome=LOC121837099|UniProtKB=A0ACM8G257 A0ACM8G257 LOC121837099 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8052475|UniProtKB=A0ACM8EX42 A0ACM8EX42 LOC8052475 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED nucleotidyltransferase#PC00174;transferase#PC00220 IXOSC|EnsemblGenome=LOC8052383|UniProtKB=A0ACM8FU62 A0ACM8FU62 Las PTHR10949:SF0 LIPOYL SYNTHASE LIPOYL SYNTHASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 Lipoate_biosynthesis#P02750>Lipoate synthase#P03004 IXOSC|EnsemblGenome=LOC8041003|UniProtKB=A0ACM8DT51 A0ACM8DT51 LOC8041003 PTHR31296:SF1 UPF0565 PROTEIN C2ORF69 MITOCHONDRIAL PROTEIN C2ORF69 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8035382|UniProtKB=A0ACM8FU30 A0ACM8FU30 LOC8035382 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8038576|UniProtKB=A0ACM8FSR6 A0ACM8FSR6 LOC8038576 PTHR11785:SF528 AMINO ACID TRANSPORTER LD25378P L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC121046288|UniProtKB=A0ACM8FEN2 A0ACM8FEN2 LOC121046288 PTHR36943:SF2 CCHC-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322966|UniProtKB=A0ACM8E2L6 A0ACM8E2L6 LOC115322966 PTHR24007:SF7 BRCA1-ASSOCIATED PROTEIN BRCA1-ASSOCIATED PROTEIN ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;protein modification by small protein conjugation or removal#GO:0070647;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;signal transduction#GO:0007165;cellular process#GO:0009987;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;intracellular signaling cassette#GO:0141124;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8031116|UniProtKB=A0ACM8FDJ1 A0ACM8FDJ1 Usp32 PTHR21646:SF76 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 32 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of TORC1 signaling#GO:1904263;regulation of protein stability#GO:0031647;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of TOR signaling#GO:0032006;regulation of TORC1 signaling#GO:1903432;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;positive regulation of TOR signaling#GO:0032008;regulation of biological quality#GO:0065008;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8050889|UniProtKB=A0ACM8FTZ3 A0ACM8FTZ3 LOC8050889 PTHR24238:SF83 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120838732|UniProtKB=A0ACM8EJS7 A0ACM8EJS7 LOC120838732 PTHR13817:SF175 TITIN NEUROGLIAN structural protein#PC00211 IXOSC|EnsemblGenome=LOC120836012|UniProtKB=A0ACM8EYR2 A0ACM8EYR2 LOC120836012 PTHR12736:SF29 LANC-LIKE PROTEIN LANC-LIKE PROTEIN 3 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cellular response to alcohol#GO:1905957;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of signaling#GO:0023051;regulation of abscisic acid-activated signaling pathway#GO:0009787;regulation of response to stimulus#GO:0048583;regulation of response to alcohol#GO:1901419 IXOSC|EnsemblGenome=LOC8028410|UniProtKB=A0ACM8E118 A0ACM8E118 LOC8028410 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC115331601|UniProtKB=A0ACM8ED67 A0ACM8ED67 LOC115331601 PTHR31077:SF1 U4/U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN U4_U6.U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 27 KDA PROTEIN nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8041821|UniProtKB=A0ACM8DKS6 A0ACM8DKS6 asf1 PTHR12040:SF0 ANTI-SILENCING PROTEIN 1 HISTONE CHAPERONE ASF1 histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115311773|UniProtKB=A0ACM8F6A6 A0ACM8F6A6 LOC115311773 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043166|UniProtKB=A0ACM8EQG1 A0ACM8EQG1 LOC8043166 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC120848425|UniProtKB=A0ACM8F5Z7 A0ACM8F5Z7 LOC120848425 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120836837|UniProtKB=A0ACM8EGK7 A0ACM8EGK7 LOC120836837 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC121836116|UniProtKB=A0ACM8FWT5 A0ACM8FWT5 LOC121836116 PTHR10933:SF9 IMMUNOGLOBULIN-BINDING PROTEIN 1 IMMUNOGLOBULIN BINDING PROTEIN 1 protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121837191|UniProtKB=A0ACM8G3N5 A0ACM8G3N5 LOC121837191 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844307|UniProtKB=A0ACM8G007 A0ACM8G007 LOC120844307 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050662|UniProtKB=A0ACM8G462 A0ACM8G462 LOC8050662 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carnitine metabolic process#GO:0009437;cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8037870|UniProtKB=A0ACM8DIA7 A0ACM8DIA7 LOC8037870 PTHR23108:SF0 METHYLTRANSFERASE-RELATED METHYLTRANSFERASE-LIKE PROTEIN 22 protein methyltransferase activity#GO:0008276;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115310911|UniProtKB=A0ACM8DQ65 A0ACM8DQ65 LOC115310911 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE protein refolding#GO:0042026;protein metabolic process#GO:0019538;protein folding#GO:0006457;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;response to heat#GO:0009408 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC8043374|UniProtKB=A0ACM8DRF3 A0ACM8DRF3 LOC8043374 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8028204|UniProtKB=A0ACM8E8R5 A0ACM8E8R5 LOC8028204 PTHR22739:SF7 STRIATED MUSCLE ACTIVATOR OF RHO-DEPENDENT SIGNALING-RELATED EG:152A3.3 PROTEIN-RELATED positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of biological process#GO:0050789;regulation of Rho protein signal transduction#GO:0035023;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;positive regulation of signaling#GO:0023056;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of signal transduction#GO:0009967;positive regulation of RNA metabolic process#GO:0051254;regulation of cell communication#GO:0010646;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;contractile muscle fiber#GO:0043292;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;sarcomere#GO:0030017;membraneless organelle#GO:0043228;myofibril#GO:0030016;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8032744|UniProtKB=A0ACM8EBW1 A0ACM8EBW1 Gos28 PTHR21094:SF2 GOS-28 SNARE- RELATED GOLGI SNAP RECEPTOR COMPLEX MEMBER 1 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;localization#GO:0051179;intra-Golgi vesicle-mediated transport#GO:0006891;cellular component organization#GO:0016043;vesicle fusion#GO:0006906 cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;Golgi stack#GO:0005795;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;cytoplasm#GO:0005737;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 SNARE protein#PC00034;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120844246|UniProtKB=A0ACM8EZB3 A0ACM8EZB3 LOC120844246 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311604|UniProtKB=A0ACM8FLL8 A0ACM8FLL8 LOC115311604 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120846796|UniProtKB=A0ACM8F387 A0ACM8F387 LOC120846796 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine-containing compound catabolic process#GO:0072523;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC121048631|UniProtKB=A0ACM8G4M0 A0ACM8G4M0 LOC121048631 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036859|UniProtKB=A0ACM8G0E2 A0ACM8G0E2 LOC8036859 PTHR23406:SF96 MALIC ENZYME-RELATED MALIC ENZYME oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115310977|UniProtKB=A0ACM8EEN9 A0ACM8EEN9 LOC115310977 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;chromatin#GO:0000785;chromosome#GO:0005694;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8037121|UniProtKB=A0ACM8DPA1 A0ACM8DPA1 LOC8037121 PTHR24171:SF18 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8030581|UniProtKB=A0ACM8EI90 A0ACM8EI90 LOC8030581 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8050440|UniProtKB=A0ACM8F9P0 A0ACM8F9P0 LOC8050440 PTHR21682:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 COILED-COIL DOMAIN-CONTAINING PROTEIN 149 IXOSC|EnsemblGenome=LOC115329399|UniProtKB=A0ACM8EAE7 A0ACM8EAE7 LOC115329399 PTHR18849:SF0 LEUCINE RICH REPEAT PROTEIN CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 410 IXOSC|EnsemblGenome=LOC8027342|UniProtKB=A0ACM8DPG4 A0ACM8DPG4 LOC8027342 PTHR11804:SF79 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED MITOCHONDRIAL INTERMEDIATE PEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8043603|UniProtKB=A0ACM8DGR5 A0ACM8DGR5 LOC8043603 PTHR20531:SF1 N-ALPHA-ACETYLTRANSFERASE 40 N-ALPHA-ACETYLTRANSFERASE 40 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acyltransferase activity#GO:0140186;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8039090|UniProtKB=A0ACM8DT13 A0ACM8DT13 Zpr1 PTHR10876:SF7 ZINC FINGER PROTEIN ZPR1 ZINC FINGER PROTEIN ZPR1 protein binding#GO:0005515;binding#GO:0005488 protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121835548|UniProtKB=A0ACM8FUU9 A0ACM8FUU9 LOC121835548 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121833388|UniProtKB=A0ACM8FKF8 A0ACM8FKF8 LOC121833388 PTHR23088:SF55 NITRILASE-RELATED NITRILASE AND FRAGILE HISTIDINE TRIAD FUSION PROTEIN NITFHIT hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8040519|UniProtKB=A0ACM8ELP1 A0ACM8ELP1 LOC8040519 PTHR11732:SF482 ALDO/KETO REDUCTASE LD24679P oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120843732|UniProtKB=A0ACM8EWU0 A0ACM8EWU0 LOC120843732 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314997|UniProtKB=A0ACM8DUU4 A0ACM8DUU4 Rpt4 PTHR23073:SF31 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 10B isomerase activity#GO:0016853;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 regulation of protein-containing complex assembly#GO:0043254;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to stress#GO:0006950;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;regulation of DNA-templated transcription initiation#GO:2000142;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;response to endoplasmic reticulum stress#GO:0034976;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;ERAD pathway#GO:0036503;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of gene expression#GO:0010468 endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome complex#GO:0000502;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC8032156|UniProtKB=A0ACM8EXC5 A0ACM8EXC5 LOC8032156 PTHR46004:SF3 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN A RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 IXOSC|EnsemblGenome=LOC115321387|UniProtKB=A0ACM8F806 A0ACM8F806 LOC115321387 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8023568|UniProtKB=A0ACM8EDZ5 A0ACM8EDZ5 LOC8023568 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120842224|UniProtKB=A0ACM8ET25 A0ACM8ET25 LOC120842224 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316759|UniProtKB=A0ACM8DWA0 A0ACM8DWA0 LOC115316759 PTHR16260:SF3 SIMILAR TO 1700123O20RIK PROTEIN SIMILAR TO 1700123O20RIK PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8033788|UniProtKB=A0ACM8DR88 A0ACM8DR88 POLDIP2 PTHR14289:SF16 F-BOX ONLY PROTEIN 3 POLYMERASE DELTA-INTERACTING PROTEIN 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 response to stimulus#GO:0050896;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA biosynthetic process#GO:0071897;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nucleoid#GO:0009295;organelle#GO:0043226;mitochondrial nucleoid#GO:0042645;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 IXOSC|EnsemblGenome=LOC115329990|UniProtKB=A0ACM8EBP7 A0ACM8EBP7 LOC115329990 PTHR10537:SF3 DNA PRIMASE LARGE SUBUNIT DNA PRIMASE LARGE SUBUNIT nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;DNA-templated DNA replication#GO:0006261;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA replication initiation#GO:0006270;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228 primase#PC00189 DNA replication#P00017>Primase#P00528 IXOSC|EnsemblGenome=LOC8050741|UniProtKB=A0ACM8DLT6 A0ACM8DLT6 LOC8050741 PTHR45679:SF5 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 2 ER DEGRADATION-ENHANCING ALPHA-MANNOSIDASE-LIKE PROTEIN 1 endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to stress#GO:0033554;cellular response to topologically incorrect protein#GO:0035967;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556 IXOSC|EnsemblGenome=LOC8040826|UniProtKB=A0ACM8ERM6 A0ACM8ERM6 LOC8040826 PTHR11475:SF4 OXIDASE/PEROXIDASE PEROXINECTIN A oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC8024854|UniProtKB=A0ACM8DRL6 A0ACM8DRL6 LOC8024854 PTHR31334:SF1 SMITH-MAGENIS SYNDROME REGION GENE 8 PROTEIN GUANINE NUCLEOTIDE EXCHANGE PROTEIN SMCR8 protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC8026166|UniProtKB=A0ACM8FUF7 A0ACM8FUF7 LOC8026166 PTHR12619:SF35 RFX TRANSCRIPTION FACTOR FAMILY TRANSCRIPTION FACTOR RFX4 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8037574|UniProtKB=A0ACM8FZM2 A0ACM8FZM2 LOC8037574 PTHR47537:SF2 CUBILIN SOL1, ISOFORM C plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8039042|UniProtKB=A0ACM8DSF6 A0ACM8DSF6 Ercc1 PTHR12749:SF0 EXCISION REPAIR CROSS-COMPLEMENTING 1 ERCC1 DNA EXCISION REPAIR PROTEIN ERCC-1 binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded DNA binding#GO:0003697;damaged DNA binding#GO:0003684;DNA binding#GO:0003677 response to stress#GO:0006950;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;response to radiation#GO:0009314;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;response to UV#GO:0009411;macromolecule metabolic process#GO:0043170;cellular response to abiotic stimulus#GO:0071214;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;cellular response to radiation#GO:0071478;mitotic recombination#GO:0006312;cellular response to stress#GO:0033554 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC115332475|UniProtKB=A0ACM8FYK6 A0ACM8FYK6 LOC115332475 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8025388|UniProtKB=A0ACM8EC54 A0ACM8EC54 raskol PTHR10194:SF60 RAS GTPASE-ACTIVATING PROTEINS RAS GTPASE-ACTIVATING PROTEIN RASKOL GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8028252|UniProtKB=A0ACM8EBR8 A0ACM8EBR8 Rpn11 PTHR10410:SF5 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED UBIQUITIN C-TERMINAL HYDROLASE PSMD14 catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;deubiquitinase activity#GO:0101005 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;proteasome complex#GO:0000502;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368 translation factor#PC00223;translation initiation factor#PC00224 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 IXOSC|EnsemblGenome=LOC115322751|UniProtKB=A0ACM8E317 A0ACM8E317 LOC115322751 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121833518|UniProtKB=A0ACM8FLG0 A0ACM8FLG0 LOC121833518 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;organelle organization#GO:0006996;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC115330952|UniProtKB=A0ACM8EBG5 A0ACM8EBG5 LOC115330952 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115333003|UniProtKB=A0ACM8FPM5 A0ACM8FPM5 PTHR33958:SF2 PROTEIN C8ORF37 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 418 cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ciliary base#GO:0097546;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;cell projection#GO:0042995 IXOSC|EnsemblGenome=LOC120850139|UniProtKB=A0ACM8FA77 A0ACM8FA77 LOC120850139 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041197|UniProtKB=A0ACM8DNL3 A0ACM8DNL3 LOC8041197 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;protein folding#GO:0006457;protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to heat#GO:0009408;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC120845332|UniProtKB=A0ACM8F0D6 A0ACM8F0D6 LOC120845332 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331131|UniProtKB=A0ACM8G6A6 A0ACM8G6A6 LOC115331131 PTHR14196:SF17 ODD-SKIPPED - RELATED SUBFAMILY NOT NAMED zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8023323|UniProtKB=A0ACM8DQQ2 A0ACM8DQQ2 LOC8023323 PTHR48182:SF2 PROTEIN SERAC1 PROTEIN SERAC1 IXOSC|EnsemblGenome=LOC115328148|UniProtKB=A0ACM8F0E1 A0ACM8F0E1 LOC115328148 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8051390|UniProtKB=A0ACM8EK32 A0ACM8EK32 LOC8051390 PTHR10680:SF39 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 IXOSC|EnsemblGenome=LOC8023608|UniProtKB=A0ACM8DTV2 A0ACM8DTV2 LOC8023608 PTHR19282:SF544 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115310810|UniProtKB=A0ACM8FPS1 A0ACM8FPS1 PTHR10663:SF376 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PH AND SEC7 DOMAIN-CONTAINING PROTEIN ruffle#GO:0001726;cell projection membrane#GO:0031253;ruffle membrane#GO:0032587;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC120842348|UniProtKB=A0ACM8EUN7 A0ACM8EUN7 LOC120842348 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8039847|UniProtKB=A0ACM8FVT1 A0ACM8FVT1 RhoGAP15B PTHR45899:SF2 RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C RHO GTPASE ACTIVATING PROTEIN AT 15B, ISOFORM C lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;phospholipid binding#GO:0005543;anion binding#GO:0043168 regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of actin filament-based process#GO:0032970 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8039971|UniProtKB=A0ACM8ETS0 A0ACM8ETS0 LOC8039971 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC8023077|UniProtKB=A0ACM8E6P7 A0ACM8E6P7 LOC8023077 PTHR13011:SF0 TFIIF-ALPHA GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 1 RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;transcription factor binding#GO:0008134;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TFIIFalpha#P00663;Transcription regulation by bZIP transcription factor#P00055>TFIIFalpha#P01391 IXOSC|EnsemblGenome=LOC8025135|UniProtKB=A0ACM8DJ26 A0ACM8DJ26 LOC8025135 PTHR12824:SF8 GROUP XII SECRETORY PHOSPHOLIPASE A2 FAMILY MEMBER GXIVSPLA2, ISOFORM A hydrolase#PC00121;lipase#PC00143;phospholipase#PC00186 IXOSC|EnsemblGenome=LOC120846254|UniProtKB=A0ACM8F157 A0ACM8F157 LOC120846254 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120838877|UniProtKB=A0ACM8EK61 A0ACM8EK61 LOC8053666 PTHR24346:SF112 MAP/MICROTUBULE AFFINITY-REGULATING KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121836471|UniProtKB=A0ACM8FYW4 A0ACM8FYW4 LOC121836471 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120846474|UniProtKB=A0ACM8F3B1 A0ACM8F3B1 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023416|UniProtKB=A0ACM8DSX4 A0ACM8DSX4 PTHR13495:SF0 NEFA-INTERACTING NUCLEAR PROTEIN NIP30 PSME3-INTERACTING PROTEIN membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115320164|UniProtKB=A0ACM8E0Q2 A0ACM8E0Q2 LOC115320164 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8026275|UniProtKB=A0ACM8E1Q2 A0ACM8E1Q2 Srrm1 PTHR23148:SF0 SERINE/ARGININE REGULATED NUCLEAR MATRIX PROTEIN SERINE_ARGININE REPETITIVE MATRIX PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120838896|UniProtKB=A0ACM8EK72 A0ACM8EK72 LOC120838896 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC120846976|UniProtKB=A0ACM8F4I7 A0ACM8F4I7 LOC120846976 PTHR24329:SF520 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN UNC-42 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell development#GO:0048468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8025575|UniProtKB=A0ACM8EF59 A0ACM8EF59 LOC8025575 PTHR11040:SF203 ZINC/IRON TRANSPORTER FI18611P1-RELATED zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324 metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;cellular process#GO:0009987;inorganic cation import across plasma membrane#GO:0098659;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115331593|UniProtKB=A0ACM8FQY5 A0ACM8FQY5 LOC115331593 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121838523|UniProtKB=A0ACM8G919 A0ACM8G919 LOC121838523 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318923|UniProtKB=A0ACM8DYK1 A0ACM8DYK1 LOC115318923 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115322610|UniProtKB=A0ACM8EY15 A0ACM8EY15 LOC115322610 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115314764|UniProtKB=A0ACM8F8W2 A0ACM8F8W2 PTHR10266:SF3 CYTOCHROME C1 CYTOCHROME C1, HEME PROTEIN, MITOCHONDRIAL monoatomic cation transmembrane transporter activity#GO:0008324;electron transfer activity#GO:0009055;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;oxidoreductase activity#GO:0016491;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;oxidoreductase activity, acting on diphenols and related substances as donors#GO:0016679;transmembrane transporter activity#GO:0022857;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078 respiratory electron transport chain#GO:0022904;cellular process#GO:0009987;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;mitochondrial ATP synthesis coupled electron transport#GO:0042775;electron transport chain#GO:0022900;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;generation of precursor metabolites and energy#GO:0006091;aerobic electron transport chain#GO:0019646;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Huntington disease#P00029>Cytochrome c#P00785;FAS signaling pathway#P00020>CytochromeC#P00620;ATP synthesis#P02721>Cyt bc1#P02799 IXOSC|EnsemblGenome=LOC120844044|UniProtKB=A0ACM8EXN1 A0ACM8EXN1 LOC120844044 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052999|UniProtKB=A0ACM8F2E7 A0ACM8F2E7 LOC8052999 PTHR22619:SF1 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZINC FINGER SWIM DOMAIN-CONTAINING PROTEIN 8 transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul2-RING ubiquitin ligase complex#GO:0031462;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC8028193|UniProtKB=A0ACM8DJM0 A0ACM8DJM0 LOC8028193 PTHR43827:SF3 2,5-DIKETO-D-GLUCONIC ACID REDUCTASE NADP-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN reductase#PC00198 IXOSC|EnsemblGenome=LOC115309132|UniProtKB=A0ACM8F2B7 A0ACM8F2B7 LOC115309132 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8025958|UniProtKB=A0ACM8EG75 A0ACM8EG75 LOC8025958 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115324950|UniProtKB=A0ACM8EKZ2 A0ACM8EKZ2 LOC115324950 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC121834873|UniProtKB=A0ACM8FS42 A0ACM8FS42 LOC121834873 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC8040936|UniProtKB=A0ACM8DYY4 A0ACM8DYY4 LOC8040936 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032588|UniProtKB=A0ACM8DJL3 A0ACM8DJL3 Uxt PTHR13345:SF15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 10 PROTEIN UXT transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115309766|UniProtKB=A0ACM8DP42 A0ACM8DP42 LOC115309766 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120844516|UniProtKB=A0ACM8EZ02 A0ACM8EZ02 LOC120844516 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120836020|UniProtKB=A0ACM8EHD4 A0ACM8EHD4 LOC120836020 PTHR24394:SF62 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121838340|UniProtKB=A0ACM8G7Q6 A0ACM8G7Q6 LOC121838340 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115308667|UniProtKB=A0ACM8G916 A0ACM8G916 LOC115308667 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8032213|UniProtKB=A0ACM8DJ95 A0ACM8DJ95 LOC8032213 PTHR15938:SF0 TBP-1 INTERACTING PROTEIN HOMOLOGOUS-PAIRING PROTEIN 2 HOMOLOG molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;enzyme regulator activity#GO:0030234;binding#GO:0005488;nucleic acid binding#GO:0003676 homologous recombination#GO:0035825;reproductive process#GO:0022414;reciprocal homologous recombination#GO:0140527;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nucleobase-containing compound metabolic process#GO:0006139;meiotic chromosome segregation#GO:0045132;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;cell cycle process#GO:0022402;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;homologous chromosome pairing at meiosis#GO:0007129;cellular process#GO:0009987;organelle organization#GO:0006996;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;condensed chromosome#GO:0000793;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 DNA metabolism protein#PC00009 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;General transcription regulation#P00023>TBP#P00670;General transcription by RNA polymerase I#P00022>SL1 complex#P00653 IXOSC|EnsemblGenome=LOC8043216|UniProtKB=A0ACM8DL03 A0ACM8DL03 mAChR-B PTHR24247:SF191 5-HYDROXYTRYPTAMINE RECEPTOR MUSCARINIC ACETYLCHOLINE RECEPTOR, B-TYPE, ISOFORM A molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;postsynaptic neurotransmitter receptor activity#GO:0098960;acetylcholine receptor activity#GO:0015464;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594 response to chemical#GO:0042221;acetylcholine receptor signaling pathway#GO:0095500;cellular response to nitrogen compound#GO:1901699;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;trans-synaptic signaling#GO:0099537;response to oxygen-containing compound#GO:1901700 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cell junction#GO:0030054;dendritic tree#GO:0097447;dendrite#GO:0030425 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GqPCR#P00730;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 IXOSC|EnsemblGenome=LOC8030002|UniProtKB=A0ACM8DYP8 A0ACM8DYP8 ArgRS-m PTHR11956:SF11 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, MITOCHONDRIAL-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8051435|UniProtKB=A0ACM8DLU1 A0ACM8DLU1 LOC8051435 PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8027856|UniProtKB=A0ACM8DQ58 A0ACM8DQ58 LOC8027856 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=LOC120839678|UniProtKB=A0ACM8EMV9 A0ACM8EMV9 LOC120839678 PTHR10629:SF61 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA methyltransferase#PC00013;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8031179|UniProtKB=A0ACM8FR08 A0ACM8FR08 LOC8031179 PTHR24241:SF190 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CARDIOACCELERATORY PEPTIDE RECEPTOR-LIKE PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;response to chemical#GO:0042221;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;signaling#GO:0023052;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121047373|UniProtKB=A0ACM8FH05 A0ACM8FH05 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8031218|UniProtKB=A0ACM8DI27 A0ACM8DI27 LOC8031218 PTHR22738:SF10 RASSF RAS ASSOCIATION DOMAIN-CONTAINING PROTEIN 1 HOMOLOG cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8033752|UniProtKB=A0ACM8EEP3 A0ACM8EEP3 LOC8033752 PTHR15574:SF39 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 6 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 Cul4-RING E3 ubiquitin ligase complex#GO:0080008;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8052310|UniProtKB=A0ACM8FQY3 A0ACM8FQY3 Lpin PTHR12181:SF73 LIPIN PHOSPHATIDATE PHOSPHATASE transcription coactivator activity#GO:0003713;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;transcription regulator activity#GO:0140110 positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701;lipid catabolic process#GO:0016042;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;fatty acid catabolic process#GO:0009062;cellular response to chemical stimulus#GO:0070887;oxoacid metabolic process#GO:0043436;response to oxygen-containing compound#GO:1901700;cellular response to endogenous stimulus#GO:0071495;glycerolipid metabolic process#GO:0046486;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to hormone stimulus#GO:0032870;small molecule catabolic process#GO:0044282;response to endogenous stimulus#GO:0009719;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;regulation of biological process#GO:0050789;neutral lipid metabolic process#GO:0006638;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;acylglycerol metabolic process#GO:0006639;fatty acid metabolic process#GO:0006631;cellular response to insulin stimulus#GO:0032869;triglyceride metabolic process#GO:0006641;lipid metabolic process#GO:0006629;regulation of nucleobase-containing compound metabolic process#GO:0019219;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;monocarboxylic acid catabolic process#GO:0072329;cellular response to nitrogen compound#GO:1901699;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;carboxylic acid catabolic process#GO:0046395;glycerolipid biosynthetic process#GO:0045017;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;response to nitrogen compound#GO:1901698;regulation of RNA metabolic process#GO:0051252;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular response to peptide hormone stimulus#GO:0071375;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8025057|UniProtKB=A0ACM8ECD5 A0ACM8ECD5 LOC8025057 PTHR24224:SF6 CARDIOACCELERATORY PEPTIDE RECEPTOR-RELATED NEMATOCIN RECEPTOR 1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121837021|UniProtKB=A0ACM8G0S6 A0ACM8G0S6 LOC121837021 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318168|UniProtKB=A0ACM8F4I5 A0ACM8F4I5 LOC115318168 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED nucleotidyltransferase#PC00174;transferase#PC00220 IXOSC|EnsemblGenome=LOC8036709|UniProtKB=A0ACM8G801 A0ACM8G801 LOC8036709 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC8024414|UniProtKB=A0ACM8E0I7 A0ACM8E0I7 PIG-P PTHR46346:SF1 PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT P GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220 IXOSC|EnsemblGenome=LOC8027821|UniProtKB=A0ACM8DJD7 A0ACM8DJD7 LOC8027821 PTHR11822:SF46 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8042851|UniProtKB=A0ACM8DKZ7 A0ACM8DKZ7 LOC8042851 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8025169|UniProtKB=A0ACM8ENX9 A0ACM8ENX9 LOC8025169 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8026107|UniProtKB=A0ACM8G8Q6 A0ACM8G8Q6 LOC8026107 PTHR21445:SF1 ENDONUCLEASE IV ENDODEOXYRIBONUCLEASE IV ENDONUCLEASE 4 ISOFORM X1-RELATED nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;base-excision repair#GO:0006284;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC120839905|UniProtKB=A0ACM8EMT1 A0ACM8EMT1 LOC120839905 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115318710|UniProtKB=A0ACM8FNZ5 A0ACM8FNZ5 PTHR24070:SF258 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN RAL-A ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 Ras Pathway#P04393>Ral#P04550 IXOSC|EnsemblGenome=LOC8034062|UniProtKB=A0ACM8G1I7 A0ACM8G1I7 Nubpl PTHR42961:SF4 IRON-SULFUR PROTEIN NUBPL IRON-SULFUR CLUSTER TRANSFER PROTEIN NUBPL iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;NADH dehydrogenase complex assembly#GO:0010257;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;iron-sulfur cluster assembly#GO:0016226;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC8026669|UniProtKB=A0ACM8FVD8 A0ACM8FVD8 LOC8026669 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121835649|UniProtKB=A0ACM8FV64 A0ACM8FV64 LOC121835649 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842350|UniProtKB=A0ACM8ETK7 A0ACM8ETK7 LOC120842350 PTHR16172:SF2 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE JET FUEL, ISOFORM A membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8035179|UniProtKB=A0ACM8E8B2 A0ACM8E8B2 LOC8035179 PTHR23115:SF170 TRANSLATION FACTOR ELONGATION FACTOR 1-ALPHA 2 ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 translation factor#PC00223 IXOSC|EnsemblGenome=LOC115311578|UniProtKB=A0ACM8EXQ6 A0ACM8EXQ6 LOC115311578 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8043964|UniProtKB=A0ACM8G4J9 A0ACM8G4J9 LOC8043964 PTHR33977:SF1 ZINC ION BINDING PROTEIN ZINC ION BINDING PROTEIN IXOSC|EnsemblGenome=LOC121835909|UniProtKB=A0ACM8FW98 A0ACM8FW98 LOC121835909 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837318|UniProtKB=A0ACM8G384 A0ACM8G384 LOC121837318 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115308951|UniProtKB=A0ACM8EWF5 A0ACM8EWF5 LOC115308951 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040805|UniProtKB=A0ACM8FAK5 A0ACM8FAK5 LOC8040805 PTHR11552:SF233 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI02019P catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115322949|UniProtKB=A0ACM8E3T3 A0ACM8E3T3 LOC115322949 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8025514|UniProtKB=A0ACM8DZK7 A0ACM8DZK7 Adck1 PTHR43173:SF19 ABC1 FAMILY PROTEIN AARF DOMAIN-CONTAINING PROTEIN KINASE 1 cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;mitochondrion organization#GO:0007005;homeostatic process#GO:0042592;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;lipid homeostasis#GO:0055088 intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115320791|UniProtKB=A0ACM8E156 A0ACM8E156 LOC115320791 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8053190|UniProtKB=A0ACM8DRF1 A0ACM8DRF1 LOC8053190 PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115315799|UniProtKB=A0ACM8DVA5 A0ACM8DVA5 LOC115315799 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036039|UniProtKB=A0ACM8DPE2 A0ACM8DPE2 LOC8036039 PTHR24365:SF555 TOLL-LIKE RECEPTOR MSTPROX-RELATED molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8043091|UniProtKB=A0ACM8E953 A0ACM8E953 LOC8043091 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 IXOSC|EnsemblGenome=LOC8042046|UniProtKB=A0ACM8EN27 A0ACM8EN27 LOC8042046 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115311377|UniProtKB=A0ACM8ELF5 A0ACM8ELF5 LOC115311377 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120836034|UniProtKB=A0ACM8FMN7 A0ACM8FMN7 LOC120836034 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC120839221|UniProtKB=A0ACM8G604 A0ACM8G604 LOC120839221 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115325095|UniProtKB=A0ACM8G3A4 A0ACM8G3A4 LOC115325095 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040952|UniProtKB=A0ACM8FE08 A0ACM8FE08 LOC8040952 PTHR23147:SF133 SERINE/ARGININE RICH SPLICING FACTOR SERINE_ARGININE-RICH SPLICING FACTOR 10 intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115309989|UniProtKB=A0ACM8F3N9 A0ACM8F3N9 LOC115309989 PTHR43605:SF17 ACYL-COENZYME A SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;monocarboxylic acid biosynthetic process#GO:0072330;purine-containing compound metabolic process#GO:0072521;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052741|UniProtKB=A0ACM8F826 A0ACM8F826 LOC8052741 PTHR46007:SF8 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8032041|UniProtKB=A0ACM8F7D0 A0ACM8F7D0 PTHR22722:SF17 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR ISOFORM X1 IXOSC|EnsemblGenome=LOC115325248|UniProtKB=A0ACM8F2S3 A0ACM8F2S3 LOC115325248 PTHR45080:SF8 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE 1 ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043 membrane#GO:0016020;neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424 IXOSC|EnsemblGenome=LOC115331473|UniProtKB=A0ACM8FYH7 A0ACM8FYH7 LOC115331473 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293 sodium ion transport#GO:0006814;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115333080|UniProtKB=A0ACM8EF00 A0ACM8EF00 LOC115333080 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 transporter#PC00227 IXOSC|EnsemblGenome=LOC115328244|UniProtKB=A0ACM8EP99 A0ACM8EP99 LOC115328244 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121834243|UniProtKB=A0ACM8FPK7 A0ACM8FPK7 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321109|UniProtKB=A0ACM8FFA0 A0ACM8FFA0 LOC115321109 PTHR47160:SF13 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034255|UniProtKB=A0ACM8FLX9 A0ACM8FLX9 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8042254|UniProtKB=A0ACM8FMW9 A0ACM8FMW9 LOC8042254 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC120849749|UniProtKB=A0ACM8F7B3 A0ACM8F7B3 LOC120849749 PTHR22812:SF112 CHROMOBOX PROTEIN CHROMATOR, ISOFORM A-RELATED chromatin binding#GO:0003682;binding#GO:0005488 cellular component assembly#GO:0022607;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;intracellular organelle#GO:0043229;chromosome, centromeric region#GO:0000775;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694 IXOSC|EnsemblGenome=LOC8042534|UniProtKB=A0ACM8EHL2 A0ACM8EHL2 Ddrgk1 PTHR48176:SF1 DDRGK DOMAIN-CONTAINING PROTEIN 1 DDRGK DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389 IXOSC|EnsemblGenome=LOC120839202|UniProtKB=A0ACM8EKZ6 A0ACM8EKZ6 LOC120839202 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835204|UniProtKB=A0ACM8FSU8 A0ACM8FSU8 LOC121835204 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120841201|UniProtKB=A0ACM8EQS9 A0ACM8EQS9 LOC120841201 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8033742|UniProtKB=A0ACM8EEV1 A0ACM8EEV1 PTHR11533:SF174 PROTEASE M1 ZINC METALLOPROTEASE PUROMYCIN-SENSITIVE AMINOPEPTIDASE-RELATED exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235 catabolic process#GO:0009056;peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121836314|UniProtKB=A0ACM8FYC1 A0ACM8FYC1 LOC121836314 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8024922|UniProtKB=A0ACM8EZ08 A0ACM8EZ08 LOC8024922 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8053818|UniProtKB=A0ACM8E0J3 A0ACM8E0J3 PTHR13032:SF6 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM21 protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;mitochondrial transmembrane transport#GO:1990542;protein transport#GO:0015031;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743 IXOSC|EnsemblGenome=LOC8030514|UniProtKB=A0ACM8DVS5 A0ACM8DVS5 Tctp PTHR11991:SF23 TRANSLATIONALLY CONTROLLED TUMOR PROTEIN-RELATED TRANSLATIONALLY-CONTROLLED TUMOR PROTEIN calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 negative regulation of catabolic process#GO:0009895;negative regulation of cell communication#GO:0010648;negative regulation of apoptotic signaling pathway#GO:2001234;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of metabolic process#GO:0009892;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of autophagy#GO:0010507;regulation of catabolic process#GO:0009894;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of apoptotic process#GO:0043066;negative regulation of response to stimulus#GO:0048585;negative regulation of programmed cell death#GO:0043069;regulation of metabolic process#GO:0019222 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC120848225|UniProtKB=A0ACM8FWY2 A0ACM8FWY2 LOC120848225 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC8037184|UniProtKB=A0ACM8DK23 A0ACM8DK23 RfC4 PTHR11669:SF5 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 2 catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity#GO:0140657 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;replication fork#GO:0005657;chromosome#GO:0005694 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 IXOSC|EnsemblGenome=LOC8026853|UniProtKB=A0ACM8E145 A0ACM8E145 PTHR47678:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 31 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115331992|UniProtKB=A0ACM8EE17 A0ACM8EE17 LOC115331992 PTHR24377:SF1039 IP01015P-RELATED SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8054030|UniProtKB=A0ACM8DLL3 A0ACM8DLL3 LOC8054030 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120841150|UniProtKB=A0ACM8EQM2 A0ACM8EQM2 LOC120841150 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8026280|UniProtKB=A0ACM8E2B8 A0ACM8E2B8 LOC8026280 PTHR23301:SF110 CHITIN BINDING PERITROPHIN-A LD43683P structural molecule activity#GO:0005198;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8040143|UniProtKB=A0ACM8DKG6 A0ACM8DKG6 LOC8040143 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8040291|UniProtKB=A0ACM8E8H7 A0ACM8E8H7 LOC8040291 PTHR12784:SF28 STEERIN PROTEIN NEURON NAVIGATOR multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;multicellular organismal process#GO:0032501;system development#GO:0048731;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 IXOSC|EnsemblGenome=LOC8031195|UniProtKB=A0ACM8DW46 A0ACM8DW46 LOC8031195 PTHR12443:SF9 TRANSLOCATION PROTEIN SEC62 TRANSLOCATION PROTEIN SEC62 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transmembrane protein transporter activity#GO:0008320 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization to endoplasmic reticulum#GO:0072599;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;protein targeting#GO:0006605;localization within membrane#GO:0051668;post-translational protein targeting to membrane, translocation#GO:0031204;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8027581|UniProtKB=A0ACM8EZF0 A0ACM8EZF0 LOC8027581 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8053123|UniProtKB=A0ACM8DM31 A0ACM8DM31 LOC8053123 PTHR22055:SF0 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN PDGF-ASSOCIATED PROTEIN 28 KDA HEAT- AND ACID-STABLE PHOSPHOPROTEIN cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115328434|UniProtKB=A0ACM8EXR3 A0ACM8EXR3 LOC115328434 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115313493|UniProtKB=A0ACM8FGV5 A0ACM8FGV5 LOC115313493 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836908|UniProtKB=A0ACM8EG13 A0ACM8EG13 LOC120836908 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039048|UniProtKB=A0ACM8DRB0 A0ACM8DRB0 LOC8039048 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC121837921|UniProtKB=A0ACM8G714 A0ACM8G714 LOC121837921 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;protein modification by small protein conjugation or removal#GO:0070647;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;protein sumoylation#GO:0016925;regulation of gene expression#GO:0010468;metabolic process#GO:0008152 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 IXOSC|EnsemblGenome=LOC8030914|UniProtKB=A0ACM8FQS1 A0ACM8FQS1 PTHR43272:SF118 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;cell differentiation#GO:0030154;nucleoside phosphate metabolic process#GO:0006753;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lipid droplet#GO:0005811 ligase#PC00142 IXOSC|EnsemblGenome=LOC8032442|UniProtKB=A0ACM8E9G1 A0ACM8E9G1 LOC8032442 PTHR12862:SF0 BADF TYPE ATPASE DOMAIN-CONTAINING PROTEIN N-ACETYL-D-GLUCOSAMINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200 IXOSC|EnsemblGenome=LOC121833400|UniProtKB=A0ACM8FKV5 A0ACM8FKV5 LOC121833400 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8052648|UniProtKB=A0ACM8E1Q3 A0ACM8E1Q3 LOC8052648 PTHR16500:SF3 BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY BRCA2-INTERACTING TRANSCRIPTIONAL REPRESSOR EMSY nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120838527|UniProtKB=A0ACM8EL15 A0ACM8EL15 LOC120838527 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115312185|UniProtKB=A0ACM8F7H4 A0ACM8F7H4 LOC115312185 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316599|UniProtKB=A0ACM8DWS0 A0ACM8DWS0 TBCC PTHR15139:SF0 TUBULIN FOLDING COFACTOR C TUBULIN-SPECIFIC CHAPERONE C cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120842489|UniProtKB=A0ACM8EV26 A0ACM8EV26 LOC120842489 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8025157|UniProtKB=A0ACM8DPB8 A0ACM8DPB8 LOC8025157 PTHR10997:SF18 IMPORTIN-7, 8, 11 D-IMPORTIN 7_RANBP7 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;protein localization to organelle#GO:0033365;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;cytosol#GO:0005829;nucleus#GO:0005634 transporter#PC00227 IXOSC|EnsemblGenome=LOC121837858|UniProtKB=A0ACM8G5F6 A0ACM8G5F6 LOC121837858 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8027931|UniProtKB=A0ACM8E6R9 A0ACM8E6R9 LOC8027931 PTHR43899:SF49 RH59310P RH59310P catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8031232|UniProtKB=A0ACM8DI17 A0ACM8DI17 LOC8031232 PTHR39072:SF4 RE48511P 63 KDA SPERM FLAGELLAR MEMBRANE PROTEIN IXOSC|EnsemblGenome=LOC120837000|UniProtKB=A0ACM8FV06 A0ACM8FV06 LOC120837000 PTHR11349:SF116 NUCLEOSIDE DIPHOSPHATE KINASE NUCLEOSIDE DIPHOSPHATE KINASE B phosphotransferase activity, phosphate group as acceptor#GO:0016776;nucleoside diphosphate kinase activity#GO:0004550;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity#GO:0016740 nucleoside triphosphate biosynthetic process#GO:0009142;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;cellular process#GO:0009987;nucleoside triphosphate metabolic process#GO:0009141;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase#PC00137;transferase#PC00220 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dTDP kinase#P02919;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCDP kinase#P02914;De novo purine biosynthesis#P02738>dGDP kinase#P02889;De novo pyrimidine ribonucleotides biosythesis#P02740>CDP kinase#P02929;De novo purine biosynthesis#P02738>dADP kinase#P02907;De novo pyrimidine ribonucleotides biosythesis#P02740>UDP kinase#P02923;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;De novo purine biosynthesis#P02738>GDP kinase#P02891;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUDP kinase#P02912 IXOSC|EnsemblGenome=LOC115311799|UniProtKB=A0ACM8F6K8 A0ACM8F6K8 LOC115311799 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033032|UniProtKB=A0ACM8FKH5 A0ACM8FKH5 LOC8033032 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8038937|UniProtKB=A0ACM8E3P2 A0ACM8E3P2 LOC8038937 PTHR16105:SF0 RNA-BINDING REGION-CONTAINING PROTEIN 3 RNA-BINDING REGION-CONTAINING PROTEIN 3 snRNA binding#GO:0017069;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002;binding#GO:0005488 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120836224|UniProtKB=A0ACM8EGH7 A0ACM8EGH7 LOC120836224 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121046199|UniProtKB=A0ACM8FDD3 A0ACM8FDD3 LOC121046199 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120844650|UniProtKB=A0ACM8EZ85 A0ACM8EZ85 LOC120844650 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8023423|UniProtKB=A0ACM8EFN5 A0ACM8EFN5 LOC8023423 PTHR14776:SF1 CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1 CADHERIN-LIKE AND PC-ESTERASE DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC115322442|UniProtKB=A0ACM8EPV5 A0ACM8EPV5 LOC115322442 PTHR15829:SF13 PROTEIN KINASE PKN/PRK1, EFFECTOR FAM65 N-TERMINAL DOMAIN-CONTAINING PROTEIN non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8053416|UniProtKB=A0ACM8DLS8 A0ACM8DLS8 LOC8053416 PTHR11242:SF20 ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED AIP_AIPL N-TERMINAL FKBP-TYPE PPIASE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein modification process#GO:0036211;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121045504|UniProtKB=A0ACM8FEG0 A0ACM8FEG0 LOC121045504 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115326528|UniProtKB=A0ACM8FB42 A0ACM8FB42 LOC115326528 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836028|UniProtKB=A0ACM8FXQ2 A0ACM8FXQ2 LOC121836028 PTHR43245:SF51 BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA HYDROXY-DELTA-5-STEROID DEHYDROGENASE, 3 BETA- AND STEROID DELTA-ISOMERASE 1 IXOSC|EnsemblGenome=LOC8033147|UniProtKB=A0ACM8ESP3 A0ACM8ESP3 LOC8033147 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115311764|UniProtKB=A0ACM8DR98 A0ACM8DR98 LOC115311764 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032870|UniProtKB=A0ACM8DH65 A0ACM8DH65 LOC8032870 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8041933|UniProtKB=A0ACM8F9J5 A0ACM8F9J5 Khc PTHR47968:SF78 CENTROMERE PROTEIN E KINESIN HEAVY CHAIN ISOFORM X1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 mitotic cell cycle#GO:0000278;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cell cycle#GO:0007049;cellular process#GO:0009987 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081 IXOSC|EnsemblGenome=LOC120842328|UniProtKB=A0ACM8ETL5 A0ACM8ETL5 LOC120842328 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837204|UniProtKB=A0ACM8G427 A0ACM8G427 LOC121837204 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121834088|UniProtKB=A0ACM8FQ40 A0ACM8FQ40 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8029057|UniProtKB=A0ACM8DT44 A0ACM8DT44 LOC8029057 PTHR47412:SF1 FI01434P-RELATED FI01434P-RELATED IXOSC|EnsemblGenome=LOC121833283|UniProtKB=A0ACM8FK78 A0ACM8FK78 LOC121833283 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115312905|UniProtKB=A0ACM8DSA1 A0ACM8DSA1 LOC115312905 PTHR33198:SF22 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838185|UniProtKB=A0ACM8G823 A0ACM8G823 LOC121838185 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115315950|UniProtKB=A0ACM8DVT5 A0ACM8DVT5 LOC115315950 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034475|UniProtKB=A0ACM8ELH8 A0ACM8ELH8 LOC8034475 PTHR15822:SF4 TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN 5'-TYROSYL-DNA PHOSPHODIESTERASE hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;hydrolase activity#GO:0016787 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121045908|UniProtKB=A0ACM8FT62 A0ACM8FT62 LOC121045908 PTHR24049:SF43 CRUMBS FAMILY MEMBER EGF-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8026818|UniProtKB=A0ACM8FLN5 A0ACM8FLN5 LOC8026818 PTHR24364:SF28 LP06937P MEMBRANE GLYCOPROTEIN LIG-1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8052463|UniProtKB=A0ACM8E8T3 A0ACM8E8T3 LOC8052463 PTHR11556:SF1 FRUCTOSE-1,6-BISPHOSPHATASE-RELATED FRUCTOSE-1,6-BISPHOSPHATASE ISOZYME 2 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;sugar-phosphatase activity#GO:0050308;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;hexose biosynthetic process#GO:0019319;gluconeogenesis#GO:0006094;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;carbohydrate biosynthetic process#GO:0016051 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121;carbohydrate phosphatase#PC00066 IXOSC|EnsemblGenome=LOC8040032|UniProtKB=A0ACM8E260 A0ACM8E260 PTHR10809:SF6 VESICLE-ASSOCIATED MEMBRANE PROTEIN-ASSOCIATED PROTEIN AT11025P-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120844527|UniProtKB=A0ACM8EYY5 A0ACM8EYY5 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043085|UniProtKB=A0ACM8FMR8 A0ACM8FMR8 LOC8043085 PTHR44006:SF1 U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 40 KDA PROTEIN intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904 mRNA splicing#P00058>U5#P01474 IXOSC|EnsemblGenome=LOC8026568|UniProtKB=A0ACM8ENQ9 A0ACM8ENQ9 LOC8026568 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8029739|UniProtKB=A0ACM8E513 A0ACM8E513 Pkc98E PTHR24351:SF201 RIBOSOMAL PROTEIN S6 KINASE PROTEIN KINASE C catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8040354|UniProtKB=A0ACM8EUH1 A0ACM8EUH1 PTHR46103:SF3 RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL RRNA METHYLTRANSFERASE 1, MITOCHONDRIAL catalytic activity, acting on a rRNA#GO:0140102;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;rRNA (guanine) methyltransferase activity#GO:0016435;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC115314104|UniProtKB=A0ACM8DTW1 A0ACM8DTW1 LOC115314104 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121836811|UniProtKB=A0ACM8G0P1 A0ACM8G0P1 LOC121836811 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837250|UniProtKB=A0ACM8G3Y0 A0ACM8G3Y0 LOC121837250 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8025811|UniProtKB=A0ACM8DGF2 A0ACM8DGF2 LOC8025811 PTHR23407:SF6 ATPASE INHIBITOR/5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE ATPASE INHIBITOR, MITOCHONDRIAL binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879;molecular function inhibitor activity#GO:0140678;catalytic activity#GO:0003824;ligase activity#GO:0016874;molecular function regulator activity#GO:0098772 homeostasis of number of cells#GO:0048872;tetrahydrofolate biosynthetic process#GO:0046654;immune system process#GO:0002376;tetrapyrrole metabolic process#GO:0033013;tetrahydrofolate metabolic process#GO:0046653;porphyrin-containing compound biosynthetic process#GO:0006779;erythrocyte differentiation#GO:0030218;anatomical structure development#GO:0048856;heme biosynthetic process#GO:0006783;modified amino acid metabolic process#GO:0006575;homeostatic process#GO:0042592;cell development#GO:0048468;cell differentiation#GO:0030154;tetrapyrrole biosynthetic process#GO:0033014;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;myeloid cell differentiation#GO:0030099;folic acid-containing compound metabolic process#GO:0006760;developmental process#GO:0032502;pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;metabolic process#GO:0008152;multicellular organismal-level homeostasis#GO:0048871;cellular developmental process#GO:0048869;cellular process#GO:0009987;pigment metabolic process#GO:0042440;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;hemopoiesis#GO:0030097;multicellular organismal process#GO:0032501 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ligase#PC00142 IXOSC|EnsemblGenome=LOC120836825|UniProtKB=A0ACM8EGI7 A0ACM8EGI7 LOC120836825 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8040953|UniProtKB=A0ACM8ECB7 A0ACM8ECB7 LOC8040953 PTHR46205:SF3 LOQUACIOUS, ISOFORM B PROTEIN LOQUACIOUS binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of gene silencing by regulatory ncRNA#GO:0060966;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;siRNA processing#GO:0030422;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348 IXOSC|EnsemblGenome=LOC121046150|UniProtKB=A0ACM8FDE9 A0ACM8FDE9 LOC121046150 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026510|UniProtKB=A0ACM8DRR7 A0ACM8DRR7 PTHR44329:SF317 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120836730|UniProtKB=A0ACM8EFQ6 A0ACM8EFQ6 LOC120836730 PTHR22997:SF0 PIH1 DOMAIN-CONTAINING PROTEIN 1 PIH1 DOMAIN-CONTAINING PROTEIN 1 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;rRNA processing#GO:0006364;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8039973|UniProtKB=A0ACM8ETR6 A0ACM8ETR6 LOC8039973 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC115331573|UniProtKB=A0ACM8F1D1 A0ACM8F1D1 LOC115331573 PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;catabolic process#GO:0009056;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC120838854|UniProtKB=A0ACM8ELG7 A0ACM8ELG7 LOC120838854 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120847857|UniProtKB=A0ACM8F403 A0ACM8F403 LOC120847857 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026339|UniProtKB=A0ACM8DHM4 A0ACM8DHM4 ArgRS PTHR11956:SF5 ARGINYL-TRNA SYNTHETASE ARGININE--TRNA LIGASE, CYTOPLASMIC ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8051027|UniProtKB=A0ACM8EBB3 A0ACM8EBB3 LOC8051027 PTHR11822:SF44 NADP-SPECIFIC ISOCITRATE DEHYDROGENASE ISOCITRATE DEHYDROGENASE [NADP] CYTOPLASMIC nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;purine nucleotide metabolic process#GO:0006163;nicotinamide nucleotide metabolic process#GO:0046496;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;cytosol#GO:0005829;mitochondrion#GO:0005739;microbody#GO:0042579 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8026457|UniProtKB=A0ACM8EGQ8 A0ACM8EGQ8 LOC8026457 PTHR23113:SF252 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANYL-RELEASING PROTEIN 3 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Ras protein signal transduction#GO:0007265;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC120843149|UniProtKB=A0ACM8EV83 A0ACM8EV83 LOC120843149 PTHR45913:SF5 EPM2A-INTERACTING PROTEIN 1 HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849429|UniProtKB=A0ACM8F838 A0ACM8F838 LOC120849429 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120838807|UniProtKB=A0ACM8EJZ5 A0ACM8EJZ5 LOC120838807 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031706|UniProtKB=A0ACM8E7M5 A0ACM8E7M5 LOC8031706 PTHR24289:SF24 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 21-HYDROXYLASE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;cellular process#GO:0009987;regulation of hormone levels#GO:0010817;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone biosynthetic process#GO:0042446;steroid metabolic process#GO:0008202;hormone metabolic process#GO:0042445 IXOSC|EnsemblGenome=LOC120840279|UniProtKB=A0ACM8FMR9 A0ACM8FMR9 LOC120840279 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121835235|UniProtKB=A0ACM8FTH4 A0ACM8FTH4 LOC121835235 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025119|UniProtKB=A0ACM8DV01 A0ACM8DV01 LOC8025119 PTHR12740:SF4 JNK1/MAPK8-ASSOCIATED MEMBRANE PROTEIN JNK1_MAPK8-ASSOCIATED MEMBRANE PROTEIN enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115308165|UniProtKB=A0ACM8DRF7 A0ACM8DRF7 Noa36 PTHR13214:SF1 ZINC FINGER PROTEIN 330 ZINC FINGER PROTEIN 330 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8028330|UniProtKB=A0ACM8DJN1 A0ACM8DJN1 LOC8028330 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC121835724|UniProtKB=A0ACM8FVH6 A0ACM8FVH6 LOC121835724 PTHR10126:SF42 TATA-BOX BINDING PROTEIN TATA-BOX-BINDING PROTEIN gene expression#GO:0010467;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>TBP#P00657;Transcription regulation by bZIP transcription factor#P00055>TBP#P01399;Huntington disease#P00029>TBP#P00779 IXOSC|EnsemblGenome=LOC115311107|UniProtKB=A0ACM8DQG2 A0ACM8DQG2 LOC115311107 PTHR34988:SF1 PROTEIN, PUTATIVE-RELATED PPC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036436|UniProtKB=A0ACM8DZJ7 A0ACM8DZJ7 sigmar PTHR12757:SF1 TUMOR NECROSIS FACTOR INDUCED PROTEIN PROTEIN SALIVARY GLANDS MARRED regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120849871|UniProtKB=A0ACM8FZ76 A0ACM8FZ76 LOC120849871 PTHR19446:SF415 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8036288|UniProtKB=A0ACM8DTV8 A0ACM8DTV8 Xpac PTHR10142:SF0 DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA REPAIR PROTEIN COMPLEMENTING XP-A CELLS DNA binding#GO:0003677;damaged DNA binding#GO:0003684;binding#GO:0005488;nucleic acid binding#GO:0003676 chromosome organization#GO:0051276;cellular response to abiotic stimulus#GO:0071214;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;response to UV#GO:0009411;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;interstrand cross-link repair#GO:0036297;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;cellular response to light stimulus#GO:0071482;response to radiation#GO:0009314;response to stress#GO:0006950;organelle organization#GO:0006996;cellular response to stress#GO:0033554;cellular response to radiation#GO:0071478;cellular response to environmental stimulus#GO:0104004;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;response to abiotic stimulus#GO:0009628 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleotide-excision repair complex#GO:0000109;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121834630|UniProtKB=A0ACM8FQV7 A0ACM8FQV7 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8053002|UniProtKB=A0ACM8E5A4 A0ACM8E5A4 LOC8053002 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034858|UniProtKB=A0ACM8DTH2 A0ACM8DTH2 LOC8034858 PTHR12514:SF1 ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR TRANSCRIPTION AND MRNA EXPORT FACTOR ENY2 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;RNA localization#GO:0006403;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;nuclear transport#GO:0051169;nuclear export#GO:0051168;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;regulation of DNA-templated transcription#GO:0006355;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nitrogen compound transport#GO:0071705;regulation of gene expression#GO:0010468;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;metabolic process#GO:0008152 organelle#GO:0043226;transcription export complex 2#GO:0070390;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SAGA-type complex#GO:0070461;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;SAGA complex#GO:0000124;DUBm complex#GO:0071819;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8033219|UniProtKB=A0ACM8DYG8 A0ACM8DYG8 LOC8033219 PTHR21600:SF81 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD4, MITOCHONDRIAL isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120841649|UniProtKB=A0ACM8FTK4 A0ACM8FTK4 LOC120841649 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028677|UniProtKB=A0ACM8ENL4 A0ACM8ENL4 LOC8028677 PTHR21245:SF10 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN PROTEIN TUMOROUS TESTIS-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121047384|UniProtKB=A0ACM8FH11 A0ACM8FH11 LOC121047384 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC115319219|UniProtKB=A0ACM8DZR8 A0ACM8DZR8 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120838272|UniProtKB=A0ACM8EJE3 A0ACM8EJE3 Acat1 PTHR18919:SF156 ACETYL-COA C-ACYLTRANSFERASE ACETYL-COA ACETYLTRANSFERASE, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;steroid metabolic process#GO:0008202;sterol metabolic process#GO:0016125 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042 CCKR signaling map#P06959>ACAT1#G06992;CCKR signaling map#P06959>ACAT1#G07285 IXOSC|EnsemblGenome=LOC8050640|UniProtKB=A0ACM8F3N5 A0ACM8F3N5 LOC8050640 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;microbody#GO:0042579 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836550|UniProtKB=A0ACM8FYM5 A0ACM8FYM5 LOC121836550 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838645|UniProtKB=A0ACM8G5V6 A0ACM8G5V6 LOC120838645 PTHR11384:SF59 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER LYSOSOMAL COBALAMIN TRANSPORTER ABCD4 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8051796|UniProtKB=A0ACM8DLM4 A0ACM8DLM4 LOC8051796 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8042160|UniProtKB=A0ACM8FGI4 A0ACM8FGI4 LOC8042160 PTHR23319:SF4 GRAM DOMAIN CONTAINING 1B, ISOFORM E AT22714P-RELATED steroid binding#GO:0005496;transporter activity#GO:0005215;sterol transfer activity#GO:0120015;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;sterol binding#GO:0032934;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;binding#GO:0005488 sterol transport#GO:0015918;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;intracellular transport#GO:0046907;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;intracellular sterol transport#GO:0032366;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane contact site#GO:0044232;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC8033946|UniProtKB=A0ACM8E4K5 A0ACM8E4K5 LOC8033946 PTHR14167:SF124 SH3 DOMAIN-CONTAINING ENDOPHILIN-A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;presynapse#GO:0098793;cytosol#GO:0005829;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;synapse#GO:0045202 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115321780|UniProtKB=A0ACM8EL90 A0ACM8EL90 LOC115321780 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8026047|UniProtKB=A0ACM8FNR3 A0ACM8FNR3 Trim9 PTHR24099:SF15 E3 UBIQUITIN-PROTEIN LIGASE TRIM36-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM9 neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;developmental process#GO:0032502;neuron differentiation#GO:0030182;cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;axon guidance#GO:0007411;axon development#GO:0061564;neuron projection development#GO:0031175;cellular process#GO:0009987;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;neuron development#GO:0048666;axonogenesis#GO:0007409;system development#GO:0048731;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468 neuron projection#GO:0043005;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8029324|UniProtKB=A0ACM8E1H7 A0ACM8E1H7 LOC8029324 PTHR47640:SF11 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED RNA-BINDING PROTEIN 42 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 IXOSC|EnsemblGenome=LOC120845191|UniProtKB=A0ACM8FGN6 A0ACM8FGN6 LOC120845191 PTHR24060:SF136 METABOTROPIC GLUTAMATE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8026191|UniProtKB=A0ACM8DPQ5 A0ACM8DPQ5 LOC8026191 PTHR11588:SF13 TUBULIN TUBULIN EPSILON CHAIN purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167 cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 IXOSC|EnsemblGenome=LOC8052988|UniProtKB=A0ACM8DLI8 A0ACM8DLI8 LOC8052988 PTHR24068:SF503 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 IXOSC|EnsemblGenome=LOC8031142|UniProtKB=A0ACM8EFM0 A0ACM8EFM0 LOC8031142 PTHR12370:SF8 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE PHOSPHOLIPASE B-LIKE 3-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC8023687|UniProtKB=A0ACM8EIW5 A0ACM8EIW5 LOC8023687 PTHR40240:SF1 PLEXUS, ISOFORM A PLEXUS, ISOFORM A IXOSC|EnsemblGenome=LOC115311893|UniProtKB=A0ACM8DRD1 A0ACM8DRD1 LOC115311893 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8051548|UniProtKB=A0ACM8EXU8 A0ACM8EXU8 LOC8051548 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234;lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8028783|UniProtKB=A0ACM8DH76 A0ACM8DH76 LOC8028783 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120840929|UniProtKB=A0ACM8EQF1 A0ACM8EQF1 LOC120840929 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115320170|UniProtKB=A0ACM8FN96 A0ACM8FN96 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120846900|UniProtKB=A0ACM8F3A4 A0ACM8F3A4 LOC120846900 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8031153|UniProtKB=A0ACM8DHZ3 A0ACM8DHZ3 LOC8031153 PTHR13511:SF0 KXDL MOTIF-CONTAINING PROTEIN 1 KXDL MOTIF-CONTAINING PROTEIN 1 organelle localization#GO:0051640;lysosome localization#GO:0032418;localization#GO:0051179 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC8051902|UniProtKB=A0ACM8DLZ6 A0ACM8DLZ6 LOC8051902 PTHR31759:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 167 COILED-COIL DOMAIN-CONTAINING PROTEIN 167 IXOSC|EnsemblGenome=LOC115329937|UniProtKB=A0ACM8EAA1 A0ACM8EAA1 LOC115329937 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8035365|UniProtKB=A0ACM8DJT1 A0ACM8DJT1 LOC8035365 PTHR11636:SF140 POU DOMAIN POU DOMAIN PROTEIN 2, ISOFORM B-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8033419|UniProtKB=A0ACM8DHX0 A0ACM8DHX0 LOC8033419 PTHR21838:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 COILED-COIL DOMAIN-CONTAINING PROTEIN 137 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8051455|UniProtKB=A0ACM8DQ63 A0ACM8DQ63 Mmp1 PTHR10201:SF291 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE 1, ISOFORM C-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 extracellular structure organization#GO:0043062;metabolic process#GO:0008152;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8037800|UniProtKB=A0ACM8EKS2 A0ACM8EKS2 spg PTHR45653:SF12 DEDICATOR OF CYTOKINESIS SPONGE, ISOFORM E molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8042390|UniProtKB=A0ACM8DKX4 A0ACM8DKX4 ATPsyngamma PTHR11693:SF45 ATP SYNTHASE GAMMA CHAIN ATP SYNTHASE F(1) COMPLEX SUBUNIT GAMMA, MITOCHONDRIAL catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324 ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020 ATP synthase#PC00002 ATP synthesis#P02721>F1 gamma#P02796 IXOSC|EnsemblGenome=LOC8025891|UniProtKB=A0ACM8DZ33 A0ACM8DZ33 IntS10 PTHR16055:SF2 INTEGRATOR COMPLEX SUBUNIT 10 INTEGRATOR COMPLEX SUBUNIT 10 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;integrator complex#GO:0032039;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115327804|UniProtKB=A0ACM8G2Q6 A0ACM8G2Q6 LOC115327804 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity#GO:0016874;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC121835614|UniProtKB=A0ACM8FV69 A0ACM8FV69 LOC121835614 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115315899|UniProtKB=A0ACM8FGE6 A0ACM8FGE6 LOC115315899 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834991|UniProtKB=A0ACM8FRT8 A0ACM8FRT8 LOC121834991 PTHR11785:SF539 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER PROTEIN JHI-21 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC121837918|UniProtKB=A0ACM8G708 A0ACM8G708 LOC121837918 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8027075|UniProtKB=A0ACM8FZE7 A0ACM8FZE7 LOC8027075 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115328144|UniProtKB=A0ACM8E980 A0ACM8E980 LOC115328144 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8036477|UniProtKB=A0ACM8F7F6 A0ACM8F7F6 LOC8036477 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115308201|UniProtKB=A0ACM8FVQ5 A0ACM8FVQ5 larp PTHR22792:SF101 LUPUS LA PROTEIN-RELATED LA-RELATED PROTEIN 1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115325158|UniProtKB=A0ACM8EV96 A0ACM8EV96 LOC115325158 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030011|UniProtKB=A0ACM8EAB6 A0ACM8EAB6 PTHR31965:SF1 TRANSMEMBRANE PROTEIN 42 TRANSMEMBRANE PROTEIN 42 IXOSC|EnsemblGenome=LOC8030469|UniProtKB=A0ACM8E881 A0ACM8E881 SPoCk PTHR42861:SF29 CALCIUM-TRANSPORTING ATPASE P-TYPE CA(2+) TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;metal ion transmembrane transporter activity#GO:0046873;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8051356|UniProtKB=A0ACM8FUI7 A0ACM8FUI7 LOC8051356 PTHR12268:SF14 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROPHIN-1 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;dystrophin-associated glycoprotein complex#GO:0016010;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121835088|UniProtKB=A0ACM8FTB8 A0ACM8FTB8 LOC121835088 PTHR11977:SF57 VILLIN VILLIN-LIKE PROTEIN QUAIL binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546;ion binding#GO:0043167;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;phosphatidylinositol bisphosphate binding#GO:1902936;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phospholipid binding#GO:0005543;cytoskeletal protein binding#GO:0008092;phosphatidylinositol phosphate binding#GO:1901981 negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of supramolecular fiber organization#GO:1902903;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC115309306|UniProtKB=A0ACM8DNM9 A0ACM8DNM9 LOC115309306 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8026567|UniProtKB=A0ACM8DHY7 A0ACM8DHY7 LOC8026567 PTHR43798:SF33 MONOACYLGLYCEROL LIPASE SERINE HYDROLASE-LIKE PROTEIN DDB_G0286239 membrane#GO:0016020;cellular anatomical structure#GO:0110165 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121046179|UniProtKB=A0ACM8FMD4 A0ACM8FMD4 LOC121834825 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8043069|UniProtKB=A0ACM8G8M0 A0ACM8G8M0 LOC8043069 PTHR22692:SF26 MYOSIN VII, XV SH3 DOMAIN-CONTAINING PROTEIN actin binding motor protein#PC00040 IXOSC|EnsemblGenome=LOC121046622|UniProtKB=A0ACM8FEL8 A0ACM8FEL8 LOC121046622 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8044149|UniProtKB=A0ACM8G8V9 A0ACM8G8V9 Mad1 PTHR23168:SF0 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 nuclear division#GO:0000280;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;mitotic nuclear division#GO:0140014;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;negative regulation of sister chromatid segregation#GO:0033046;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of mitotic sister chromatid segregation#GO:0033047;attachment of mitotic spindle microtubules to kinetochore#GO:0051315;regulation of cellular process#GO:0050794;negative regulation of organelle organization#GO:0010639;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;chromosome organization#GO:0051276;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;cellular component organization#GO:0016043;negative regulation of cell cycle#GO:0045786;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;cell cycle checkpoint signaling#GO:0000075;chromosome localization#GO:0050000;regulation of cell cycle process#GO:0010564;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic spindle assembly checkpoint signaling#GO:0007094;organelle fission#GO:0048285;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;organelle localization#GO:0051640;negative regulation of chromosome organization#GO:2001251;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;mitotic metaphase chromosome alignment#GO:0007080;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;spindle#GO:0005819;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;kinetochore#GO:0000776;organelle envelope#GO:0031967;chromosome#GO:0005694;mitotic spindle#GO:0072686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687 IXOSC|EnsemblGenome=LOC115312233|UniProtKB=A0ACM8FX09 A0ACM8FX09 LOC115312233 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120842689|UniProtKB=A0ACM8EUC7 A0ACM8EUC7 LOC120842689 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120848535|UniProtKB=A0ACM8F6W7 A0ACM8F6W7 LOC120848535 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317642|UniProtKB=A0ACM8DXY0 A0ACM8DXY0 LOC115317642 PTHR10270:SF338 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-14 sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;central nervous system development#GO:0007417;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule metabolic process#GO:0010604;head development#GO:0060322;nervous system development#GO:0007399;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;neuron differentiation#GO:0030182 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 IXOSC|EnsemblGenome=LOC8043053|UniProtKB=A0ACM8EB54 A0ACM8EB54 LOC8043053 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8050965|UniProtKB=A0ACM8E113 A0ACM8E113 LOC8050965 PTHR23237:SF6 NUCLEOLAR PROTEIN FAMILY A MEMBER 1 SNORNP PROTEIN GAR1 H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 1 RNA binding#GO:0003723;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488 gene expression#GO:0010467;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;rRNA modification#GO:0000154;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;RNA-templated DNA biosynthetic process#GO:0006278;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;macromolecule modification#GO:0043412;telomere organization#GO:0032200;rRNA processing#GO:0006364 organelle lumen#GO:0043233;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8051383|UniProtKB=A0ACM8DLR7 A0ACM8DLR7 LOC8051383 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8042484|UniProtKB=A0ACM8FXZ0 A0ACM8FXZ0 LOC8042484 PTHR24064:SF714 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8033362|UniProtKB=A0ACM8EQ31 A0ACM8EQ31 LOC8033362 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121836583|UniProtKB=A0ACM8FYR6 A0ACM8FYR6 LOC121836583 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253 nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC120840475|UniProtKB=A0ACM8EPM7 A0ACM8EPM7 LOC120840475 PTHR35617:SF4 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN TYR RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029813|UniProtKB=A0ACM8E2P6 A0ACM8E2P6 LOC8029813 PTHR12280:SF42 PANTOTHENATE KINASE 4'-PHOSPHOPANTETHEINE PHOSPHATASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;kinase activity#GO:0016301;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphoric ester hydrolase activity#GO:0042578 small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;kinase#PC00137 Coenzyme A biosynthesis#P02736>Pantothenate kinase#P02885 IXOSC|EnsemblGenome=LOC115310119|UniProtKB=A0ACM8EWK6 A0ACM8EWK6 LOC115310119 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8051597|UniProtKB=A0ACM8DW84 A0ACM8DW84 LOC8051597 PTHR24355:SF1 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE-RELATED PROTEIN transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8023349|UniProtKB=A0ACM8DGV1 A0ACM8DGV1 MED19 PTHR22536:SF1 LUNG CANCER METASTASIS-RELATED LCMR1 PROTEIN MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 19 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC8040737|UniProtKB=A0ACM8DZQ4 A0ACM8DZQ4 ninaC PTHR46256:SF3 AGAP011099-PA NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;macromolecular conformation isomerase activity#GO:0120543;microfilament motor activity#GO:0000146;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;ATP-dependent activity#GO:0140657;protein serine/threonine kinase activity#GO:0004674;polypeptide conformation or assembly isomerase activity#GO:0120544 regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;cellular process#GO:0009987;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;cellular component organization or biogenesis#GO:0071840;regulation of actin filament length#GO:0030832;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066 IXOSC|EnsemblGenome=LOC121838148|UniProtKB=A0ACM8G7Y5 A0ACM8G7Y5 LOC121838148 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120844329|UniProtKB=A0ACM8EZI5 A0ACM8EZI5 LOC120844329 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8029590|UniProtKB=A0ACM8EU95 A0ACM8EU95 LOC8029590 PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;lysosome#GO:0005764 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8040786|UniProtKB=A0ACM8G6H0 A0ACM8G6H0 LOC8040786 PTHR46730:SF1 POLYCYSTIN-1 POLYCYSTIN-1-LIKE PROTEIN 1 ISOFORM X1 monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001;calcium ion transport#GO:0006816;monoatomic ion transport#GO:0006811;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC121837293|UniProtKB=A0ACM8G355 A0ACM8G355 LOC121837293 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838051|UniProtKB=A0ACM8G7Q1 A0ACM8G7Q1 LOC121838051 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8040651|UniProtKB=A0ACM8DH08 A0ACM8DH08 LOC8040651 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8038888|UniProtKB=A0ACM8DSQ3 A0ACM8DSQ3 LOC8038888 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8037311|UniProtKB=A0ACM8DK32 A0ACM8DK32 LOC8037311 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC120851098|UniProtKB=A0ACM8FRT4 A0ACM8FRT4 LOC120851098 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8032764|UniProtKB=A0ACM8DSH5 A0ACM8DSH5 LOC8032764 PTHR23074:SF173 AAA DOMAIN-CONTAINING SPASTIN hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817 axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;central nervous system neuron differentiation#GO:0021953;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;system development#GO:0048731;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC120838513|UniProtKB=A0ACM8EKR5 A0ACM8EKR5 LOC120838513 PTHR16024:SF4 XK-RELATED PROTEIN XK-RELATED PROTEIN phospholipid transport#GO:0015914;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;phagocytosis#GO:0006909;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;cell death#GO:0008219;programmed cell death#GO:0012501;localization#GO:0051179;anatomical structure development#GO:0048856;endomembrane system organization#GO:0010256;cellular process#GO:0009987;apoptotic cell clearance#GO:0043277;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;import into cell#GO:0098657;membrane invagination#GO:0010324;endocytosis#GO:0006897;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8029379|UniProtKB=A0ACM8DI28 A0ACM8DI28 LOC8029379 PTHR21461:SF40 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN BETA-1,4-GALACTOSYLTRANSFERASE GALT-1 glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8037550|UniProtKB=A0ACM8DTX6 A0ACM8DTX6 Snx1 PTHR10555:SF170 SORTING NEXIN FI18122P1 binding#GO:0005488;phosphatidylinositol binding#GO:0035091;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147 cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;retromer complex#GO:0030904;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115321369|UniProtKB=A0ACM8ENA9 A0ACM8ENA9 LOC115321369 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115329514|UniProtKB=A0ACM8FNT8 A0ACM8FNT8 PTHR12984:SF3 SCY1-RELATED S/T PROTEIN KINASE-LIKE N-TERMINAL KINASE-LIKE PROTEIN non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120838194|UniProtKB=A0ACM8EK20 A0ACM8EK20 LOC120838194 PTHR11010:SF117 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED SERINE PROTEASE 16 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8040965|UniProtKB=A0ACM8EKI9 A0ACM8EKI9 LOC8040965 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC121048591|UniProtKB=A0ACM8FJN1 A0ACM8FJN1 LOC121048591 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121838498|UniProtKB=A0ACM8G945 A0ACM8G945 LOC121838498 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115333031|UniProtKB=A0ACM8FI14 A0ACM8FI14 LOC115333031 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120838943|UniProtKB=A0ACM8ELZ3 A0ACM8ELZ3 LOC120838943 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8052578|UniProtKB=A0ACM8E728 A0ACM8E728 Eip93F PTHR21545:SF13 TRANSCRIPTION FACTOR MLR1/2 ECDYSONE-INDUCED PROTEIN 93F, ISOFORM C regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120846922|UniProtKB=A0ACM8F3H7 A0ACM8F3H7 LOC120846922 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8052360|UniProtKB=A0ACM8DPP8 A0ACM8DPP8 LOC8052360 PTHR45673:SF1 SERINE/THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 2B CATALYTIC SUBUNIT 1-RELATED phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;calmodulin binding#GO:0005516;catalytic activity#GO:0003824;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;protein binding#GO:0005515;binding#GO:0005488 cell communication#GO:0007154;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;calcineurin-mediated signaling#GO:0097720;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein phosphatase#PC00195 Wnt signaling pathway#P00057>Calcineurin#P01446 IXOSC|EnsemblGenome=LOC115308859|UniProtKB=A0ACM8DN28 A0ACM8DN28 LOC115308859 PTHR10680:SF39 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 IXOSC|EnsemblGenome=LOC115320474|UniProtKB=A0ACM8F6R2 A0ACM8F6R2 LOC115320474 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115317150|UniProtKB=A0ACM8DWS3 A0ACM8DWS3 IFT57 PTHR16011:SF0 IFT57/HIPPI INTRAFLAGELLAR TRANSPORT PROTEIN 57 HOMOLOG cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular localization#GO:0051641;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cilium organization#GO:0044782;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111 intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intraciliary transport particle B#GO:0030992;cytoskeleton#GO:0005856;Golgi apparatus#GO:0005794;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 structural protein#PC00211 Huntington disease#P00029>Hip-12#P00763;Huntington disease#P00029>Hippi#P00794 IXOSC|EnsemblGenome=LOC120844434|UniProtKB=A0ACM8FK83 A0ACM8FK83 LOC120844434 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833858|UniProtKB=A0ACM8FN47 A0ACM8FN47 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115328303|UniProtKB=A0ACM8F301 A0ACM8F301 LOC115328303 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC8037532|UniProtKB=A0ACM8G5D9 A0ACM8G5D9 LOC8037532 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;chitin metabolic process#GO:0006030;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115320777|UniProtKB=A0ACM8E149 A0ACM8E149 CPSF2 PTHR45922:SF2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 2 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC8053622|UniProtKB=A0ACM8E9W1 A0ACM8E9W1 LOC8053622 PTHR22652:SF0 NUCLEOPORIN NUP43 NUCLEOPORIN NUP43 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;nuclear protein-containing complex#GO:0140513;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC121836097|UniProtKB=A0ACM8FXB2 A0ACM8FXB2 LOC121836097 PTHR21398:SF6 AGAP007094-PA SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120841705|UniProtKB=A0ACM8ES89 A0ACM8ES89 LOC120841705 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120837907|UniProtKB=A0ACM8FQV9 A0ACM8FQV9 LOC120837907 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024145|UniProtKB=A0ACM8DHZ7 A0ACM8DHZ7 PTHR14493:SF87 UNKEMPT FAMILY MEMBER RING FINGER PROTEIN UNKEMPT IXOSC|EnsemblGenome=LOC8038046|UniProtKB=A0ACM8E6T3 A0ACM8E6T3 LOC8038046 PTHR45659:SF24 HOMEOBOX PROTEIN HOX HOMEOTIC PROTEIN ANTENNAPEDIA-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120842008|UniProtKB=A0ACM8ETX4 A0ACM8ETX4 LOC120842008 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8030284|UniProtKB=A0ACM8DGK2 A0ACM8DGK2 CCT4 PTHR11353:SF26 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT DELTA metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;protein folding chaperone complex#GO:0101031;chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 chaperonin#PC00073 IXOSC|EnsemblGenome=LOC8032709|UniProtKB=A0ACM8F5D0 A0ACM8F5D0 LOC8032709 PTHR16040:SF7 AUSTRALIN, ISOFORM A-RELATED AUSTRALIN, ISOFORM A-RELATED mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;mitotic metaphase chromosome alignment#GO:0007080;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;localization#GO:0051179;organelle fission#GO:0048285;organelle localization#GO:0051640;nuclear division#GO:0000280;chromosome localization#GO:0050000;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;organelle#GO:0043226;chromosome#GO:0005694;microtubule cytoskeleton#GO:0015630;spindle midzone#GO:0051233;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;spindle#GO:0005819 IXOSC|EnsemblGenome=LOC115318391|UniProtKB=A0ACM8DYR4 A0ACM8DYR4 LOC120839731 PTHR22902:SF53 SESQUIPEDALIAN SESQUIPEDALIAN endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;organelle organization#GO:0006996;endosomal transport#GO:0016197;vesicle organization#GO:0016050;endosome organization#GO:0007032;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;endomembrane system#GO:0012505;Golgi apparatus subcompartment#GO:0098791;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115322766|UniProtKB=A0ACM8E3K9 A0ACM8E3K9 LOC115322766 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8028389|UniProtKB=A0ACM8DPZ8 A0ACM8DPZ8 LOC8028389 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8043827|UniProtKB=A0ACM8E922 A0ACM8E922 LOC8043827 PTHR47970:SF35 KINESIN-LIKE PROTEIN KIF11 ARMADILLO REPEAT-CONTAINING KINESIN-LIKE PROTEIN microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC8050987|UniProtKB=A0ACM8F987 A0ACM8F987 DNApol-delta PTHR10322:SF23 DNA POLYMERASE CATALYTIC SUBUNIT DNA POLYMERASE DELTA CATALYTIC SUBUNIT DNA exonuclease activity#GO:0004529;transferase activity#GO:0016740;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;exonuclease activity#GO:0004527;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;3'-5'-DNA exonuclease activity#GO:0008296;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;DNA-directed DNA polymerase activity#GO:0003887;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base-excision repair#GO:0006284 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;protein-DNA complex#GO:0032993;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replisome#GO:0030894;replication fork#GO:0005657;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 IXOSC|EnsemblGenome=LOC120843233|UniProtKB=A0ACM8EVK4 A0ACM8EVK4 LOC120843233 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837290|UniProtKB=A0ACM8G350 A0ACM8G350 LOC121837290 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC120841584|UniProtKB=A0ACM8ES24 A0ACM8ES24 LOC120841584 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115329805|UniProtKB=A0ACM8EAY4 A0ACM8EAY4 LOC115329805 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120843729|UniProtKB=A0ACM8FZQ7 A0ACM8FZQ7 LOC120843729 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029433|UniProtKB=A0ACM8EEX4 A0ACM8EEX4 Dpit47 PTHR46035:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 4 HSP70_HSP90 CO-CHAPERONE CNS1 HOMOLOG heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;Hsp70 protein binding#GO:0030544;protein binding#GO:0005515 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115310646|UniProtKB=A0ACM8DQ01 A0ACM8DQ01 LOC115310646 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115332242|UniProtKB=A0ACM8EDJ2 A0ACM8EDJ2 LOC115332242 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;neurogenesis#GO:0022008;system development#GO:0048731;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;cellular process#GO:0009987;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121835371|UniProtKB=A0ACM8FTT1 A0ACM8FTT1 LOC121835371 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=LOC121836848|UniProtKB=A0ACM8G295 A0ACM8G295 LOC121836848 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029920|UniProtKB=A0ACM8G255 A0ACM8G255 LOC8029920 PTHR24240:SF236 OPSIN RPE-RETINAL G PROTEIN-COUPLED RECEPTOR transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;response to light stimulus#GO:0009416;cellular response to radiation#GO:0071478;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;detection of stimulus#GO:0051606;cellular response to light stimulus#GO:0071482;cellular process#GO:0009987;response to radiation#GO:0009314;signal transduction#GO:0007165;biological regulation#GO:0065007;cellular response to abiotic stimulus#GO:0071214;response to external stimulus#GO:0009605 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8053602|UniProtKB=A0ACM8E911 A0ACM8E911 LOC8053602 PTHR32343:SF84 SERINE/ARGININE-RICH SPLICING FACTOR LD29830P RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC115322448|UniProtKB=A0ACM8E243 A0ACM8E243 LOC115322448 PTHR15138:SF14 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;Huntington disease#P00029>TAFII130#P00806;General transcription regulation#P00023>TBP-associated factors#P00658 IXOSC|EnsemblGenome=LOC115326305|UniProtKB=A0ACM8E6S2 A0ACM8E6S2 LOC115326305 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;organelle organization#GO:0006996;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC8028215|UniProtKB=A0ACM8E1K3 A0ACM8E1K3 PTHR21719:SF2 FI06402P-RELATED FI06402P-RELATED cell development#GO:0048468;embryo development#GO:0009790;hemopoiesis#GO:0030097;cell motility#GO:0048870;cell migration#GO:0016477;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;cellular process#GO:0009987;animal organ development#GO:0048513;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;embryonic organ development#GO:0048568;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 IXOSC|EnsemblGenome=LOC8027012|UniProtKB=A0ACM8EUZ5 A0ACM8EUZ5 LOC8027012 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8032369|UniProtKB=A0ACM8F8J1 A0ACM8F8J1 LOC8032369 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120837937|UniProtKB=A0ACM8G5X9 A0ACM8G5X9 LOC120837937 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8054040|UniProtKB=A0ACM8DXN4 A0ACM8DXN4 LOC8054040 PTHR24418:SF373 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SRC42A protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;non-membrane spanning protein tyrosine kinase activity#GO:0004715;binding#GO:0005488;signaling receptor binding#GO:0005102;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular developmental process#GO:0048869;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 Parkinson disease#P00049>Src kinase#P01230;Integrin signalling pathway#P00034>Src#P00940 IXOSC|EnsemblGenome=LOC121835771|UniProtKB=A0ACM8FVQ9 A0ACM8FVQ9 LOC121835771 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838809|UniProtKB=A0ACM8EKI8 A0ACM8EKI8 LOC120838809 PTHR12802:SF184 SWI/SNF COMPLEX-RELATED BRAHMA ASSOCIATED PROTEIN 155 KDA histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;SWI/SNF complex#GO:0016514;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 IXOSC|EnsemblGenome=LOC8028621|UniProtKB=A0ACM8EKK2 A0ACM8EKK2 LOC8028621 PTHR47705:SF1 AGAP000321-PA WINGED HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844369|UniProtKB=A0ACM8EZK3 A0ACM8EZK3 LOC120844369 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051576|UniProtKB=A0ACM8G8L6 A0ACM8G8L6 LOC8051576 PTHR18966:SF391 IONOTROPIC GLUTAMATE RECEPTOR NMDA RECEPTOR 2, ISOFORM C carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;dicarboxylic acid transmembrane transporter activity#GO:0005310;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804 synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039 IXOSC|EnsemblGenome=LOC8052956|UniProtKB=A0ACM8DU35 A0ACM8DU35 Mcm6 PTHR11630:SF43 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM6 DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094;single-stranded DNA binding#GO:0003697;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cell cycle process#GO:0022402;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;cell cycle DNA replication#GO:0044786;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;mitotic cell cycle process#GO:1903047;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;MCM complex#GO:0042555;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115329080|UniProtKB=A0ACM8E9Z0 A0ACM8E9Z0 LOC115329080 PTHR46077:SF1 E3 UBIQUITIN-PROTEIN LIGASE TOPORS E3 UBIQUITIN-PROTEIN LIGASE TOPORS ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8032625|UniProtKB=A0ACM8EJJ9 A0ACM8EJJ9 LOC8032625 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC121047658|UniProtKB=A0ACM8FGQ8 A0ACM8FGQ8 LOC121047658 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8023367|UniProtKB=A0ACM8EFJ2 A0ACM8EFJ2 LOC8023367 PTHR11211:SF40 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX HOMEOBOX PROTEIN ARAUCAN-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;cell development#GO:0048468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC115327747|UniProtKB=A0ACM8FJM4 A0ACM8FJM4 LOC115327747 PTHR24241:SF117 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE S RECEPTOR-LIKE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8023515|UniProtKB=A0ACM8FDU7 A0ACM8FDU7 PTHR22754:SF45 DISCO-INTERACTING PROTEIN 2 DIP2 -RELATED DISCO-INTERACTING PROTEIN 2 ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8041823|UniProtKB=A0ACM8DKT0 A0ACM8DKT0 LOC8041823 PTHR28622:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 7 SMALL INTEGRAL MEMBRANE PROTEIN 7 IXOSC|EnsemblGenome=LOC8037273|UniProtKB=A0ACM8FJ42 A0ACM8FJ42 LOC8037273 PTHR22891:SF198 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-1 RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;single-stranded RNA binding#GO:0003727;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676 regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165 translation factor#PC00223;translation initiation factor#PC00224;translational protein#PC00263 IXOSC|EnsemblGenome=LOC121833633|UniProtKB=A0ACM8FMY3 A0ACM8FMY3 LOC121833633 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033240|UniProtKB=A0ACM8DRJ1 A0ACM8DRJ1 mesh PTHR13802:SF52 MUCIN 4-RELATED NIDOGEN-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC115326066|UniProtKB=A0ACM8F5R8 A0ACM8F5R8 LOC115326066 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037299|UniProtKB=A0ACM8DK07 A0ACM8DK07 Naa20A PTHR45910:SF1 N-ALPHA-ACETYLTRANSFERASE 20 N-ALPHA-ACETYLTRANSFERASE 20 protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein N-acyltransferase activity#GO:0140186;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;N-acetyltransferase activity#GO:0008080 regulation of actin filament-based process#GO:0032970;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043 acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC120838473|UniProtKB=A0ACM8EJC2 A0ACM8EJC2 LOC120838473 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115324944|UniProtKB=A0ACM8EU22 A0ACM8EU22 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313986|UniProtKB=A0ACM8DTC7 A0ACM8DTC7 LOC115313986 PTHR24252:SF46 ACROSIN-RELATED ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8040748|UniProtKB=A0ACM8DH26 A0ACM8DH26 LOC8040748 PTHR11010:SF128 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115329677|UniProtKB=A0ACM8FDI8 A0ACM8FDI8 LOC115329677 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120840569|UniProtKB=A0ACM8EPH9 A0ACM8EPH9 LOC120840569 PTHR10896:SF74 GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE BETA-1,3-GLUCURONYLTRANSFERASE GALACTOSYLGALACTOSYLXYLOSYLPROTEIN 3-BETA-GLUCURONOSYLTRANSFERASE P glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;chondroitin sulfate proteoglycan metabolic process#GO:0050654;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;glycoprotein biosynthetic process#GO:0009101;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120847794|UniProtKB=A0ACM8F4V1 A0ACM8F4V1 LOC120847794 PTHR10751:SF144 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 G-protein#PC00020;heterotrimeric G-protein#PC00117 IXOSC|EnsemblGenome=LOC8029100|UniProtKB=A0ACM8DHL9 A0ACM8DHL9 LOC8029100 PTHR23235:SF185 KRUEPPEL-LIKE TRANSCRIPTION FACTOR LETHAL (3) NEO38, ISOFORM L DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120838864|UniProtKB=A0ACM8EKV2 A0ACM8EKV2 LOC120838864 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046689|UniProtKB=A0ACM8FEM1 A0ACM8FEM1 LOC121046689 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8031201|UniProtKB=A0ACM8F108 A0ACM8F108 LOC8031201 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8023733|UniProtKB=A0ACM8DTH0 A0ACM8DTH0 LOC8023733 PTHR11076:SF33 DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER DNA POLYMERASE KAPPA transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;DNA-directed DNA polymerase activity#GO:0003887 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985;DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA synthesis involved in DNA replication#GO:0090592;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115331359|UniProtKB=A0ACM8EHG9 A0ACM8EHG9 LOC115331359 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8025649|UniProtKB=A0ACM8F2T5 A0ACM8F2T5 LOC8025649 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC8028595|UniProtKB=A0ACM8DQ14 A0ACM8DQ14 LOC8028595 PTHR22776:SF97 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN RE01453P signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115320381|UniProtKB=A0ACM8E073 A0ACM8E073 LOC115320381 PTHR24384:SF189 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120842488|UniProtKB=A0ACM8ETY6 A0ACM8ETY6 LOC120842488 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040254|UniProtKB=A0ACM8G1H0 A0ACM8G1H0 Oatp30B PTHR11388:SF157 ORGANIC ANION TRANSPORTER ORGANIC ANION TRANSPORTING POLYPEPTIDE 30B, ISOFORM A active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC120838380|UniProtKB=A0ACM8EKN9 A0ACM8EKN9 LOC120838380 PTHR11662:SF462 SOLUTE CARRIER FAMILY 17 FI19708P1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8025138|UniProtKB=A0ACM8G8B1 A0ACM8G8B1 LOC8025138 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836358|UniProtKB=A0ACM8FZR1 A0ACM8FZR1 LOC121836358 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120837312|UniProtKB=A0ACM8EHP4 A0ACM8EHP4 LOC120837312 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8029123|UniProtKB=A0ACM8FE04 A0ACM8FE04 LOC8029123 PTHR11227:SF17 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED AUTOPHAGY-RELATED 18A, ISOFORM E molecular adaptor activity#GO:0060090;phospholipid binding#GO:0005543;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936 macromolecule localization#GO:0033036;glycogen catabolic process#GO:0005980;macroautophagy#GO:0016236;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;intracellular protein localization#GO:0008104;energy derivation by oxidation of organic compounds#GO:0015980;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033;localization#GO:0051179;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;phagophore assembly site#GO:0000407 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121837819|UniProtKB=A0ACM8G597 A0ACM8G597 LOC121837819 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8036204|UniProtKB=A0ACM8EBG7 A0ACM8EBG7 14-3-3epsilon PTHR18860:SF176 14-3-3 PROTEIN 14-3-3 PROTEIN EPSILON protein binding#GO:0005515;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726 scaffold/adaptor protein#PC00226 Parkinson disease#P00049>14-3-3#P01238;EGF receptor signaling pathway#P00018>14-3-3#P00539;FGF signaling pathway#P00021>14-3-3#P00624 IXOSC|EnsemblGenome=LOC115329476|UniProtKB=A0ACM8ETP5 A0ACM8ETP5 LOC115329476 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121047611|UniProtKB=A0ACM8FGN3 A0ACM8FGN3 LOC121047611 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120840225|UniProtKB=A0ACM8EMY2 A0ACM8EMY2 LOC120840225 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312457|UniProtKB=A0ACM8EKE8 A0ACM8EKE8 LOC115312457 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8044066|UniProtKB=A0ACM8DYS9 A0ACM8DYS9 LOC8044066 PTHR21705:SF11 RAI16 PROTEIN-RELATED FHIP FAMILY PROTEIN CG3558 IXOSC|EnsemblGenome=LOC8041806|UniProtKB=A0ACM8DKT1 A0ACM8DKT1 LOC8041806 PTHR13028:SF0 RRNA PROCESSING PROTEIN EBNA1-BINDING PROTEIN-RELATED RRNA-PROCESSING PROTEIN EBP2-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 IXOSC|EnsemblGenome=LOC8038540|UniProtKB=A0ACM8E8E9 A0ACM8E8E9 PTHR11347:SF226 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE DUAL SPECIFICITY CALCIUM_CALMODULIN-DEPENDENT 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 1 phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532 phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120842610|UniProtKB=A0ACM8EU68 A0ACM8EU68 LOC120842610 PTHR45797:SF3 RAD54-LIKE ATP-DEPENDENT HELICASE ATRX catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094;transcription regulator activity#GO:0140110;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;transcription coregulator activity#GO:0003712 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121834681|UniProtKB=A0ACM8FQF9 A0ACM8FQF9 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121835435|UniProtKB=A0ACM8FTX4 A0ACM8FTX4 LOC121835435 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8050743|UniProtKB=A0ACM8E4N0 A0ACM8E4N0 LOC8050743 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8051637|UniProtKB=A0ACM8DML2 A0ACM8DML2 Lnk PTHR10872:SF2 SH2B ADAPTER PROTEIN LNK, ISOFORM D receptor tyrosine kinase binding#GO:0030971;signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;enzyme binding#GO:0019899;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;protein kinase binding#GO:0019901;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;signaling receptor binding#GO:0005102;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115320361|UniProtKB=A0ACM8EW55 A0ACM8EW55 LOC115320361 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115308697|UniProtKB=A0ACM8EV43 A0ACM8EV43 PTHR11915:SF456 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN, NON-ERYTHROCYTIC 5-LIKE protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 actin filament-based process#GO:0030029;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840 cell junction#GO:0030054;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8042516|UniProtKB=A0ACM8E2K4 A0ACM8E2K4 LOC8042516 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120835933|UniProtKB=A0ACM8EK22 A0ACM8EK22 LOC120835933 PTHR23189:SF102 RNA RECOGNITION MOTIF-CONTAINING PROTEIN NO-ON-TRANSIENT A RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115330879|UniProtKB=A0ACM8EI69 A0ACM8EI69 LOC115330879 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120851091|UniProtKB=A0ACM8FB31 A0ACM8FB31 LOC120851091 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8032110|UniProtKB=A0ACM8E193 A0ACM8E193 LOC8032110 PTHR19423:SF8 SH3 DOMAIN-BINDING PROTEIN 5 SH3 DOMAIN-BINDING PROTEIN 5-LIKE nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;kinase inhibitor activity#GO:0019210;protein kinase inhibitor activity#GO:0004860;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115319352|UniProtKB=A0ACM8F5U7 A0ACM8F5U7 LOC115319352 PTHR10390:SF44 HOMEOBOX PROTEIN SIX SIX HOMEOBOX 5 transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8052816|UniProtKB=A0ACM8DWR4 A0ACM8DWR4 LOC8052816 PTHR11510:SF5 MYO-INOSITOL-1 PHOSPHATE SYNTHASE INOSITOL-3-PHOSPHATE SYNTHASE 1 isomerase activity#GO:0016853;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 isomerase#PC00135 IXOSC|EnsemblGenome=LOC121047762|UniProtKB=A0ACM8FGQ5 A0ACM8FGQ5 LOC121047762 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120841246|UniProtKB=A0ACM8EQV1 A0ACM8EQV1 LOC120841246 PTHR33064:SF47 POL PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038971|UniProtKB=A0ACM8DRU2 A0ACM8DRU2 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC120846856|UniProtKB=A0ACM8F3D0 A0ACM8F3D0 LOC120846856 PTHR13710:SF162 DNA HELICASE RECQ FAMILY MEMBER ATP-DEPENDENT DNA HELICASE Q1 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromosome#GO:0005694 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8043743|UniProtKB=A0ACM8FX30 A0ACM8FX30 LOC8043743 PTHR13930:SF0 S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE S-ADENOSYL-L-METHIONINE-DEPENDENT TRNA 4-DEMETHYLWYOSINE SYNTHASE TYW1-RELATED carbohydrate derivative biosynthetic process#GO:1901137;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 lyase#PC00144 IXOSC|EnsemblGenome=LOC8038693|UniProtKB=A0ACM8G8V7 A0ACM8G8V7 LOC8038693 PTHR11311:SF30 SPONDIN KIELIN_CHORDIN-LIKE PROTEIN cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8024049|UniProtKB=A0ACM8DHW5 A0ACM8DHW5 LOC8024049 PTHR44826:SF3 SPORE COAT PROTEIN SP85 SPORE COAT PROTEIN SP85 IXOSC|EnsemblGenome=LOC120841822|UniProtKB=A0ACM8G7F8 A0ACM8G7F8 LOC120841822 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8036952|UniProtKB=A0ACM8DU08 A0ACM8DU08 LOC8036952 PTHR24279:SF128 CYTOCHROME P450 CYTOCHROME P450 12D1 DISTAL, MITOCHONDRIAL-RELATED IXOSC|EnsemblGenome=LOC8041737|UniProtKB=A0ACM8DKP6 A0ACM8DKP6 LOC8041737 PTHR10466:SF0 PHOSPHOMANNOMUTASE PHOSPHOMANNOMUTASE catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;intramolecular phosphotransferase activity#GO:0016868;isomerase activity#GO:0016853 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glycoprotein metabolic process#GO:0009100;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;hexose metabolic process#GO:0019318;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;isomerase#PC00135;mutase#PC00160 Mannose metabolism#P02752>P-Mannose mutase#P03019 IXOSC|EnsemblGenome=LOC8028822|UniProtKB=A0ACM8DT19 A0ACM8DT19 LOC8028822 PTHR13677:SF0 LD41638P LD41638P molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endosome#GO:0005768;recycling endosome#GO:0055037;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8038677|UniProtKB=A0ACM8DQU2 A0ACM8DQU2 LOC8038677 PTHR15191:SF3 PROTEIN CBG20567 PITUITARY TUMOR-TRANSFORMING GENE 1 PROTEIN-INTERACTING PROTEIN nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8028598|UniProtKB=A0ACM8E0L8 A0ACM8E0L8 LOC8028598 PTHR12378:SF7 DESUMOYLATING ISOPEPTIDASE DESUMOYLATING ISOPEPTIDASE 1 intracellular protein localization#GO:0008104;regulation of catabolic process#GO:0009894;establishment of localization#GO:0051234;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;biological regulation#GO:0065007;protein export from nucleus#GO:0006611;regulation of proteasomal protein catabolic process#GO:0061136;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;nuclear transport#GO:0051169;nuclear export#GO:0051168;protein transport#GO:0015031;regulation of protein catabolic process#GO:0042176;localization#GO:0051179;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cellular localization#GO:0051641;nucleocytoplasmic transport#GO:0006913;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC120843452|UniProtKB=A0ACM8EW62 A0ACM8EW62 LOC120843452 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042691|UniProtKB=A0ACM8E6F1 A0ACM8E6F1 PTHR10134:SF50 CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL CYTOCHROME B-C1 COMPLEX SUBUNIT RIESKE, MITOCHONDRIAL-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;mitochondrial electron transport, ubiquinol to cytochrome c#GO:0006122;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cytochrome complex#GO:0070069;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex III#GO:0045275 IXOSC|EnsemblGenome=LOC115325214|UniProtKB=A0ACM8E4L3 A0ACM8E4L3 LOC115325214 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transporter#PC00227 IXOSC|EnsemblGenome=LOC121838035|UniProtKB=A0ACM8G7L7 A0ACM8G7L7 LOC121838035 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115326183|UniProtKB=A0ACM8FJD1 A0ACM8FJD1 LOC115326183 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8028435|UniProtKB=A0ACM8DQV1 A0ACM8DQV1 LOC8028435 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC8028154|UniProtKB=A0ACM8DJL0 A0ACM8DJL0 LOC8028154 PTHR11071:SF581 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8026102|UniProtKB=A0ACM8G7E3 A0ACM8G7E3 LOC8026102 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8023143|UniProtKB=A0ACM8E768 A0ACM8E768 LOC8023143 PTHR10858:SF23 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE II catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518 cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;execution phase of apoptosis#GO:0097194;cell death#GO:0008219;apoptotic process#GO:0006915;programmed cell death#GO:0012501;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;catabolic process#GO:0009056;DNA catabolic process#GO:0006308;cellular component disassembly#GO:0022411 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC115324038|UniProtKB=A0ACM8FFX2 A0ACM8FFX2 LOC115324038 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8038499|UniProtKB=A0ACM8DS65 A0ACM8DS65 Aos1 PTHR10953:SF162 UBIQUITIN-ACTIVATING ENZYME E1 SUMO-ACTIVATING ENZYME SUBUNIT 1 thiosulfate-cyanide sulfurtransferase activity#GO:0004792;sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;ligase activity, forming carbon-sulfur bonds#GO:0016877;ATP-dependent activity#GO:0140657;catalytic activity, acting on a protein#GO:0140096;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;ligase activity#GO:0016874;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641 protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E1#P01492 IXOSC|EnsemblGenome=LOC120849994|UniProtKB=A0ACM8F9U0 A0ACM8F9U0 LOC120849994 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8023600|UniProtKB=A0ACM8FV29 A0ACM8FV29 LOC8023600 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043915|UniProtKB=A0ACM8DVE5 A0ACM8DVE5 LOC8043915 PTHR46708:SF2 TENASCIN FIBRONECTIN-LIKE extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC121836038|UniProtKB=A0ACM8FWB2 A0ACM8FWB2 LOC121836038 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8037786|UniProtKB=A0ACM8ED83 A0ACM8ED83 LOC8037786 PTHR13673:SF0 ESOPHAGEAL CANCER ASSOCIATED PROTEIN VPS35 ENDOSOMAL PROTEIN-SORTING FACTOR-LIKE vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;localization within membrane#GO:0051668;intracellular transport#GO:0046907;vesicle-mediated transport#GO:0016192;endocytic recycling#GO:0032456;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 IXOSC|EnsemblGenome=LOC120837289|UniProtKB=A0ACM8FY09 A0ACM8FY09 LOC120837289 PTHR24171:SF17 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8030003|UniProtKB=A0ACM8ELR7 A0ACM8ELR7 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8032972|UniProtKB=A0ACM8DHB0 A0ACM8DHB0 Spase25 PTHR13085:SF0 MICROSOMAL SIGNAL PEPTIDASE 25 KDA SUBUNIT SIGNAL PEPTIDASE COMPLEX SUBUNIT 2 establishment of protein localization#GO:0045184;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;primary metabolic process#GO:0044238;protein targeting#GO:0006605;localization#GO:0051179;protein metabolic process#GO:0019538 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endopeptidase complex#GO:1905369;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;peptidase complex#GO:1905368;endomembrane system#GO:0012505;protein-containing complex#GO:0032991 protease#PC00190 Vasopressin synthesis#P04395>Signal Peptidase#P04589 IXOSC|EnsemblGenome=LOC8052029|UniProtKB=A0ACM8FGY9 A0ACM8FGY9 LOC8052029 PTHR45915:SF6 TRANSCRIPTION INTERMEDIARY FACTOR ZINC FINGER PROTEIN aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;transcription regulator activity#GO:0140110;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8025128|UniProtKB=A0ACM8DJ16 A0ACM8DJ16 LOC8025128 PTHR17130:SF14 MITOCHONDRIAL OUTER MEMBRANE PROTEIN 25 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX16 HOMOLOG, MITOCHONDRIAL cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966 IXOSC|EnsemblGenome=LOC115324599|UniProtKB=A0ACM8E5C8 A0ACM8E5C8 LOC115324599 PTHR13492:SF2 RING FINGER PROTEIN 37 RING FINGER PROTEIN 37 binding#GO:0005488;acyltransferase activity#GO:0016746;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase binding#GO:0044389;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase binding#GO:0031625;aminoacyltransferase activity#GO:0016755 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120841209|UniProtKB=A0ACM8ER82 A0ACM8ER82 LOC120841209 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8040247|UniProtKB=A0ACM8E110 A0ACM8E110 LOC8040247 PTHR10024:SF374 SYNAPTOTAGMIN SYNAPTOTAGMIN-5-LIKE SNARE binding#GO:0000149;phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;protein binding#GO:0005515 synaptic signaling#GO:0099536;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;regulation of transport#GO:0051049;regulation of localization#GO:0032879;chemical synaptic transmission#GO:0007268;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;regulation of secretion#GO:0051046;localization#GO:0051179;cell communication#GO:0007154;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530 plasma membrane#GO:0005886;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8043765|UniProtKB=A0ACM8DGW0 A0ACM8DGW0 LOC8043765 PTHR21711:SF0 MITOCHONDRIAL INNER MEMBRANE PROTEASE MITOCHONDRIAL INNER MEMBRANE PROTEASE ATP23 HOMOLOG cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;mitochondrion organization#GO:0007005;biosynthetic process#GO:0009058;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;mitochondrial proton-transporting ATP synthase complex assembly#GO:0033615;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein metabolic process#GO:0019538;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120842682|UniProtKB=A0ACM8EVF5 A0ACM8EVF5 LOC120842682 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321905|UniProtKB=A0ACM8E253 A0ACM8E253 LOC115321905 PTHR44395:SF1 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC3 IXOSC|EnsemblGenome=LOC121836955|UniProtKB=A0ACM8G0N2 A0ACM8G0N2 LOC121836955 PTHR24256:SF579 TRYPTASE-RELATED WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8053450|UniProtKB=A0ACM8DM58 A0ACM8DM58 LOC8053450 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8038195|UniProtKB=A0ACM8DTU6 A0ACM8DTU6 LOC8038195 PTHR22774:SF11 CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN CHOREIN N-TERMINAL DOMAIN-CONTAINING PROTEIN lipid transfer activity#GO:0120013;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;membrane organization#GO:0061024;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endosomal transport#GO:0016197;cellular component organization or biogenesis#GO:0071840;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;lipid localization#GO:0010876;localization#GO:0051179;cellular localization#GO:0051641 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8031680|UniProtKB=A0ACM8FCM1 A0ACM8FCM1 PTHR45936:SF1 TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115309145|UniProtKB=A0ACM8FGX5 A0ACM8FGX5 LOC115309145 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035715|UniProtKB=A0ACM8FLJ5 A0ACM8FLJ5 PTHR22826:SF106 RHO GUANINE EXCHANGE FACTOR-RELATED TRIO, ISOFORM A guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 cellular developmental process#GO:0048869;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;developmental process#GO:0032502;neuron differentiation#GO:0030182;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;axon guidance#GO:0007411;neuron projection development#GO:0031175;cellular process#GO:0009987;anatomical structure development#GO:0048856;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898;cellular anatomical structure#GO:0110165;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120849462|UniProtKB=A0ACM8F8S7 A0ACM8F8S7 LOC120849462 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843291|UniProtKB=A0ACM8EVU7 A0ACM8EVU7 LOC120843291 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319997|UniProtKB=A0ACM8F4L9 A0ACM8F4L9 LOC115319997 PTHR16294:SF8 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115321503|UniProtKB=A0ACM8FY16 A0ACM8FY16 LOC121836283 PTHR11426:SF280 HISTONE H3 HISTONE H3 chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic cell cycle#GO:0000278;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;cell cycle#GO:0007049;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;kinetochore organization#GO:0051383;localization#GO:0051179;organelle fission#GO:0048285;kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;nuclear division#GO:0000280;organelle localization#GO:0051640 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 IXOSC|EnsemblGenome=LOC121836979|UniProtKB=A0ACM8G2F6 A0ACM8G2F6 LOC8029165 PTHR10845:SF259 REGULATOR OF G PROTEIN SIGNALING RGS DOMAIN-CONTAINING PROTEIN-RELATED GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of G protein-coupled receptor signaling pathway#GO:0008277;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789 membrane#GO:0016020;cytoplasmic side of plasma membrane#GO:0009898;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC120837245|UniProtKB=A0ACM8EGW1 A0ACM8EGW1 LOC120837245 PTHR23428:SF386 HISTONE H2B HISTONE H2B 1-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121837730|UniProtKB=A0ACM8G4Y3 A0ACM8G4Y3 LOC121837730 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8043058|UniProtKB=A0ACM8DL10 A0ACM8DL10 HemK1 PTHR18895:SF74 HEMK METHYLTRANSFERASE MTRF1L RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;translational termination#GO:0006415;translation#GO:0006412;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8025824|UniProtKB=A0ACM8DWH3 A0ACM8DWH3 PTHR12598:SF0 COPPER HOMEOSTASIS PROTEIN CUTC COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;copper ion binding#GO:0005507;binding#GO:0005488;small molecule binding#GO:0036094 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120844916|UniProtKB=A0ACM8F125 A0ACM8F125 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039647|UniProtKB=A0ACM8F200 A0ACM8F200 LOC8039647 PTHR19134:SF553 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE PROTEIN-TYROSINE-PHOSPHATASE hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 system development#GO:0048731;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;axon guidance#GO:0007411;axon development#GO:0061564;neuron development#GO:0048666;axonogenesis#GO:0007409;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;signal transduction#GO:0007165;cellular process#GO:0009987;neuron projection development#GO:0031175 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Axon guidance mediated by Slit/Robo#P00008>Ptp10D#P00343 IXOSC|EnsemblGenome=LOC8037269|UniProtKB=A0ACM8DZN3 A0ACM8DZN3 LOC8037269 PTHR46186:SF2 CYSTATIN CYSTATIN-RELATED cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8026824|UniProtKB=A0ACM8E4T0 A0ACM8E4T0 LOC8026824 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8032086|UniProtKB=A0ACM8FM20 A0ACM8FM20 l(2)k01209 PTHR10285:SF116 URIDINE KINASE URIDINE KINASE intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156 IXOSC|EnsemblGenome=LOC115312029|UniProtKB=A0ACM8DRK9 A0ACM8DRK9 LOC115312029 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8029887|UniProtKB=A0ACM8DJ21 A0ACM8DJ21 EMC1 PTHR21573:SF0 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 EMC complex#GO:0072546;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8023329|UniProtKB=A0ACM8E0G6 A0ACM8E0G6 LOC8023329 PTHR11575:SF48 5'-NUCLEOTIDASE-RELATED ECTO-5'-NUCLEOTIDASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8023165|UniProtKB=A0ACM8DGG9 A0ACM8DGG9 LOC8023165 PTHR43172:SF1 ADENYLOSUCCINATE LYASE ADENYLOSUCCINATE LYASE catalytic activity#GO:0003824;lyase activity#GO:0016829 purine nucleotide biosynthetic process#GO:0006164;nucleoside monophosphate biosynthetic process#GO:0009124;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;organophosphate biosynthetic process#GO:0090407;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;ribose phosphate biosynthetic process#GO:0046390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 lyase#PC00144;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>Adenosuccinate lyase#P02901;De novo purine biosynthesis#P02738>5-Phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole lyase#P02892 IXOSC|EnsemblGenome=LOC120844711|UniProtKB=A0ACM8EZ21 A0ACM8EZ21 LOC120844711 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8030699|UniProtKB=A0ACM8DHE6 A0ACM8DHE6 LOC8030699 PTHR34260:SF1 UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX ASSEMBLY FACTOR 2 cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex III assembly#GO:0034551;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8052881|UniProtKB=A0ACM8DLG4 A0ACM8DLG4 LOC8052881 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8037104|UniProtKB=A0ACM8E5G9 A0ACM8E5G9 LOC8037104 PTHR12236:SF79 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 64AA-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8034014|UniProtKB=A0ACM8FMJ3 A0ACM8FMJ3 LOC8034014 PTHR11467:SF189 HISTONE H1 HISTONE 24 chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677 negative regulation of cellular process#GO:0048523;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;regulation of metabolic process#GO:0019222;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;biological regulation#GO:0065007;regulation of DNA recombination#GO:0000018;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120848754|UniProtKB=A0ACM8F6D2 A0ACM8F6D2 LOC120848754 PTHR33273:SF4 DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED ENDONUCLEASE_EXONUCLEASE_PHOSPHATASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035894|UniProtKB=A0ACM8DJW9 A0ACM8DJW9 PMP34 PTHR45939:SF5 PEROXISOMAL MEMBRANE PROTEIN PMP34-RELATED PEROXISOMAL MEMBRANE PROTEIN PMP34 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;purine nucleotide transmembrane transporter activity#GO:0015216;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778 IXOSC|EnsemblGenome=LOC120840619|UniProtKB=A0ACM8EPH3 A0ACM8EPH3 LOC120840619 PTHR45749:SF35 ZINC FINGER MYM-TYPE PROTEIN 1 AC-LIKE TRANSPOSASE-RELATED IXOSC|EnsemblGenome=LOC115319355|UniProtKB=A0ACM8E001 A0ACM8E001 LOC115319355 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8025441|UniProtKB=A0ACM8DYV2 A0ACM8DYV2 LOC8025441 PTHR13471:SF0 TETRATRICOPEPTIDE-LIKE HELICAL NUCLEAR EXOSOME REGULATOR NRDE2 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;negative regulation of catabolic process#GO:0009895;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of RNA catabolic process#GO:1902369;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of RNA metabolic process#GO:0051253 IXOSC|EnsemblGenome=LOC120836600|UniProtKB=A0ACM8FRG1 A0ACM8FRG1 LOC120836600 PTHR24340:SF41 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN CEH-24-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC115316318|UniProtKB=A0ACM8FB92 A0ACM8FB92 LOC115316318 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120844481|UniProtKB=A0ACM8EYV4 A0ACM8EYV4 LOC120844481 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121833122|UniProtKB=A0ACM8FJM8 A0ACM8FJM8 LOC121833122 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043986|UniProtKB=A0ACM8DUZ1 A0ACM8DUZ1 arr PTHR46513:SF41 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>LRP5/6#P01431 IXOSC|EnsemblGenome=LOC121837057|UniProtKB=A0ACM8G2S2 A0ACM8G2S2 LOC121837057 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041983|UniProtKB=A0ACM8DKU5 A0ACM8DKU5 LOC8041983 PTHR22883:SF23 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC6 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8042892|UniProtKB=A0ACM8FDI4 A0ACM8FDI4 PTHR45662:SF8 PHOSPHATIDYLINOSITIDE PHOSPHATASE SAC1 PHOSPHATIDYLINOSITIDE 4-PHOSPHATASE SAC2 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerophospholipid metabolic process#GO:0006650;biological regulation#GO:0065007;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;lipid modification#GO:0030258;regulation of transport#GO:0051049;regulation of localization#GO:0032879;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phosphate-containing compound metabolic process#GO:0006796;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;phospholipid dephosphorylation#GO:0046839;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;phosphatidylinositol dephosphorylation#GO:0046856;dephosphorylation#GO:0016311 intracellular organelle#GO:0043229;endosome#GO:0005768;endocytic vesicle#GO:0030139;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;clathrin-coated vesicle#GO:0030136;endoplasmic reticulum#GO:0005783;clathrin-coated endocytic vesicle#GO:0045334;endomembrane system#GO:0012505;cytoplasm#GO:0005737 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8035329|UniProtKB=A0ACM8DJT2 A0ACM8DJT2 LOC8035329 PTHR47760:SF1 G-PROTEIN COUPLED RECEPTOR B0563.6-LIKE PROTEIN-RELATED G PROTEIN-COUPLED RECEPTOR B0563.6-RELATED G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115321341|UniProtKB=A0ACM8G2K8 A0ACM8G2K8 LOC115321341 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8031088|UniProtKB=A0ACM8EIQ7 A0ACM8EIQ7 LOC8031088 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 serine protease#PC00203 IXOSC|EnsemblGenome=LOC121836508|UniProtKB=A0ACM8FYG4 A0ACM8FYG4 LOC121836508 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032970|UniProtKB=A0ACM8DMZ4 A0ACM8DMZ4 LOC8032970 PTHR47978:SF78 FAMILY NOT NAMED SMALL MONOMERIC GTPASE heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8043883|UniProtKB=A0ACM8DL60 A0ACM8DL60 Chchd2 PTHR13523:SF2 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2, ISOFORM A-RELATED cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;mitochondrion organization#GO:0007005 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8037211|UniProtKB=A0ACM8EZB1 A0ACM8EZB1 LOC8037211 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115332197|UniProtKB=A0ACM8FN85 A0ACM8FN85 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039645|UniProtKB=A0ACM8EMC2 A0ACM8EMC2 LOC8039645 PTHR24322:SF755 PKSB RETINOL DEHYDROGENASE 10 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8034776|UniProtKB=A0ACM8DRX5 A0ACM8DRX5 LOC8034776 PTHR23349:SF68 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FI14601P DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8023610|UniProtKB=A0ACM8G8Q3 A0ACM8G8Q3 LOC8023610 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120844640|UniProtKB=A0ACM8F088 A0ACM8F088 LOC120844640 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120840820|UniProtKB=A0ACM8EPT7 A0ACM8EPT7 LOC120840820 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8024263|UniProtKB=A0ACM8DI23 A0ACM8DI23 LOC8024263 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115309321|UniProtKB=A0ACM8DNJ7 A0ACM8DNJ7 snama PTHR15439:SF0 RETINOBLASTOMA-BINDING PROTEIN 6 E3 UBIQUITIN-PROTEIN LIGASE RBBP6 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8053316|UniProtKB=A0ACM8DPB5 A0ACM8DPB5 Fer2 PTHR23349:SF97 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST BHLH DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8028100|UniProtKB=A0ACM8DJL8 A0ACM8DJL8 LOC8028100 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8037553|UniProtKB=A0ACM8DTG5 A0ACM8DTG5 LOC8037553 PTHR13650:SF2 SPATACSIN SPATACSIN cell development#GO:0048468;signaling#GO:0023052;establishment of organelle localization#GO:0051656;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular localization#GO:0051641;microtubule-based transport#GO:0099111;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle transport#GO:0048489;synaptic signaling#GO:0099536;neuron projection development#GO:0031175;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;microtubule-based movement#GO:0007018;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;system development#GO:0048731;anatomical structure development#GO:0048856;cell communication#GO:0007154;localization#GO:0051179;organelle localization#GO:0051640;trans-synaptic signaling#GO:0099537;plasma membrane bounded cell projection organization#GO:0120036;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;multicellular organismal process#GO:0032501;vesicle localization#GO:0051648;axon development#GO:0061564;axo-dendritic transport#GO:0008088;neurogenesis#GO:0022008;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular developmental process#GO:0048869;transport#GO:0006810;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;cell junction#GO:0030054;intracellular anatomical structure#GO:0005622;dendrite#GO:0030425;dendritic tree#GO:0097447;axon#GO:0030424 IXOSC|EnsemblGenome=LOC8027643|UniProtKB=A0ACM8DJ78 A0ACM8DJ78 LOC8027643 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115326173|UniProtKB=A0ACM8EKI7 A0ACM8EKI7 LOC115326173 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121835451|UniProtKB=A0ACM8FUR6 A0ACM8FUR6 LOC121835451 PTHR18966:SF602 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536 plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC120835937|UniProtKB=A0ACM8EL76 A0ACM8EL76 LOC120835937 PTHR11142:SF33 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE SYNTHASE-LIKE 1 catalytic activity#GO:0003824;intramolecular transferase activity#GO:0016866;catalytic activity, acting on a nucleic acid#GO:0140640;isomerase activity#GO:0016853;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;mRNA modification#GO:0016556;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;pseudouridine synthesis#GO:0001522;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 lyase#PC00144 IXOSC|EnsemblGenome=LOC8034391|UniProtKB=A0ACM8EDB6 A0ACM8EDB6 LOC8034391 PTHR37456:SF14 SI:CH211-266K2.1 COLLAGEN ALPHA-5(IV) CHAIN ISOFORM X1 IXOSC|EnsemblGenome=LOC8037143|UniProtKB=A0ACM8EZ06 A0ACM8EZ06 Mpi PTHR10309:SF0 MANNOSE-6-PHOSPHATE ISOMERASE MANNOSE-6-PHOSPHATE ISOMERASE intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Mannose metabolism#P02752>Mannose 6-P isomerase#P03017 IXOSC|EnsemblGenome=LOC115327258|UniProtKB=A0ACM8FY83 A0ACM8FY83 LOC120837705 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115329519|UniProtKB=A0ACM8EGK0 A0ACM8EGK0 LOC115329519 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115332493|UniProtKB=A0ACM8G5E1 A0ACM8G5E1 LOC115332493 PTHR46203:SF1 PROBABLE PEPTIDE CHAIN RELEASE FACTOR C12ORF65 MITOCHONDRIAL TRANSLATION RELEASE FACTOR IN RESCUE intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 translation release factor#PC00225 IXOSC|EnsemblGenome=LOC115317701|UniProtKB=A0ACM8EN00 A0ACM8EN00 LOC115317701 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8032154|UniProtKB=A0ACM8EL52 A0ACM8EL52 LOC8032154 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115311216|UniProtKB=A0ACM8DQJ2 A0ACM8DQJ2 LOC115311216 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8037474|UniProtKB=A0ACM8F0Q2 A0ACM8F0Q2 LOC8037474 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121047629|UniProtKB=A0ACM8FGH2 A0ACM8FGH2 LOC121047629 PTHR11686:SF77 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;metabolic process#GO:0008152;cellular process#GO:0009987;sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8043105|UniProtKB=A0ACM8DL30 A0ACM8DL30 LOC8043105 PTHR24238:SF57 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 83 G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8031220|UniProtKB=A0ACM8DI25 A0ACM8DI25 LOC8031220 PTHR27001:SF118 OS01G0253100 PROTEIN INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 ISOFORM X1 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8042059|UniProtKB=A0ACM8DTF5 A0ACM8DTF5 LOC8042059 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN antiporter activity#GO:0015297;proton transmembrane transporter activity#GO:0015078;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;monoatomic cation transmembrane transporter activity#GO:0008324 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8023594|UniProtKB=A0ACM8E303 A0ACM8E303 LOC8023594 PTHR21461:SF40 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN BETA-1,4-GALACTOSYLTRANSFERASE GALT-1 glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8040742|UniProtKB=A0ACM8E4W0 A0ACM8E4W0 LOC8040742 PTHR45928:SF1 RE38146P RE38146P IXOSC|EnsemblGenome=LOC120838769|UniProtKB=A0ACM8FRR2 A0ACM8FRR2 LOC120838769 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;enzyme regulator activity#GO:0030234 positive regulation of protein ubiquitination#GO:0031398;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;regulation of protein modification process#GO:0031399;negative regulation of cellular process#GO:0048523;regulation of protein ubiquitination#GO:0031396;regulation of apoptotic process#GO:0042981;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121834664|UniProtKB=A0ACM8FRJ1 A0ACM8FRJ1 LOC121834664 PTHR12463:SF0 OXYGENASE-RELATED ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE ALKB HOMOLOG 4 dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010 contractile ring#GO:0070938;midbody#GO:0030496;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120839675|UniProtKB=A0ACM8EM81 A0ACM8EM81 LOC120839675 PTHR44490:SF1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 EUKARYOTIC TRANSLATION ELONGATION FACTOR 1 EPSILON-1 enzyme activator activity#GO:0008047;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067;regulation of cell communication#GO:0010646;positive regulation of apoptotic signaling pathway#GO:2001235;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stress#GO:0080134;positive regulation of apoptotic process#GO:0043065;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translation elongation factor#PC00222;translation factor#PC00223 IXOSC|EnsemblGenome=LOC8023963|UniProtKB=A0ACM8DXK9 A0ACM8DXK9 PTHR15708:SF4 ACTIN BUNDLING/MISSING IN METASTASIS-RELATED FI21477P1-RELATED protein binding#GO:0005515;lipid binding#GO:0008289;phospholipid binding#GO:0005543;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115312281|UniProtKB=A0ACM8G3R0 A0ACM8G3R0 LOC115312281 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115314033|UniProtKB=A0ACM8EPU1 A0ACM8EPU1 LOC115314033 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8033748|UniProtKB=A0ACM8E3Y8 A0ACM8E3Y8 LOC8033748 PTHR16528:SF2 GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING GOLGI-ASSOCIATED PDZ AND COILED-COIL MOTIF-CONTAINING PROTEIN protein binding#GO:0005515;transmembrane transporter binding#GO:0044325;binding#GO:0005488 regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of protein localization#GO:0032880;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network transport vesicle#GO:0030140;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115312160|UniProtKB=A0ACM8FRF1 A0ACM8FRF1 LOC115312160 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115313031|UniProtKB=A0ACM8EPR6 A0ACM8EPR6 LOC115313031 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034584|UniProtKB=A0ACM8DXW4 A0ACM8DXW4 LOC8034584 PTHR18934:SF213 ATP-DEPENDENT RNA HELICASE 3'-5' RNA HELICASE YTHDC2 helicase activity#GO:0004386;isomerase activity#GO:0016853;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8039812|UniProtKB=A0ACM8DXM6 A0ACM8DXM6 LOC8039812 PTHR45705:SF1 FI20236P1 FI20236P1 GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8033103|UniProtKB=A0ACM8DHG8 A0ACM8DHG8 LOC8033103 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 macromolecule localization#GO:0033036;protein localization to Golgi apparatus#GO:0034067;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8041022|UniProtKB=A0ACM8E2D2 A0ACM8E2D2 LOC8041022 PTHR41148:SF1 LP09875P LP09875P IXOSC|EnsemblGenome=LOC8050834|UniProtKB=A0ACM8F117 A0ACM8F117 LOC8050834 PTHR45636:SF54 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED TWIN OF EYELESS, ISOFORM D RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;animal gross anatomical part developmental process#GO:0160108;head development#GO:0060322;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;multicellular organism development#GO:0007275;developmental process#GO:0032502;sensory organ development#GO:0007423 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC115317042|UniProtKB=A0ACM8DX32 A0ACM8DX32 LOC115317042 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8028891|UniProtKB=A0ACM8F8J6 A0ACM8F8J6 PTHR24072:SF306 RHO FAMILY GTPASE RHO-RELATED GTP-BINDING PROTEIN RHOH catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;protein kinase binding#GO:0019901;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515 cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;regulation of biological quality#GO:0065008;establishment or maintenance of cell polarity#GO:0007163;cortical cytoskeleton organization#GO:0030865;actin filament-based process#GO:0030029;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of developmental process#GO:0050793;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cell shape#GO:0008360;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure morphogenesis#GO:0022603;actin filament organization#GO:0007015;regulation of actin filament-based process#GO:0032970;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 G-protein#PC00020;small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8050521|UniProtKB=A0ACM8E7T6 A0ACM8E7T6 LOC8050521 PTHR14549:SF2 TRANSMEMBRANE PROTEIN 223 TRANSMEMBRANE PROTEIN 223 IXOSC|EnsemblGenome=LOC115309088|UniProtKB=A0ACM8DNB2 A0ACM8DNB2 LOC115309088 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320000|UniProtKB=A0ACM8DZR4 A0ACM8DZR4 LOC115320000 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8023512|UniProtKB=A0ACM8ECM9 A0ACM8ECM9 LOC8023512 PTHR13467:SF3 CUE DOMAIN CONTAINING PROTEIN 1 CUE DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8052507|UniProtKB=A0ACM8DP40 A0ACM8DP40 Dph1 PTHR10762:SF1 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 1 cellular process#GO:0009987;metabolic process#GO:0008152;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 IXOSC|EnsemblGenome=LOC115329487|UniProtKB=A0ACM8E9M5 A0ACM8E9M5 LOC115329487 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314616|UniProtKB=A0ACM8DU40 A0ACM8DU40 LOC115314616 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8043699|UniProtKB=A0ACM8FIL8 A0ACM8FIL8 Caf1-105 PTHR15271:SF4 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT B protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;nucleosome organization#GO:0034728 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8030331|UniProtKB=A0ACM8DGR4 A0ACM8DGR4 RpII18 PTHR47227:SF5 DNA-DIRECTED RNA POLYMERASE SUBUNIT K DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;transcription by RNA polymerase II#GO:0006366;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665 DNA-directed RNA polymerase#PC00019 General transcription regulation#P00023>RNA Polymerase II#P00660;Transcription regulation by bZIP transcription factor#P00055>RNA Polymerase II#P01388 IXOSC|EnsemblGenome=LOC121047418|UniProtKB=A0ACM8FEU3 A0ACM8FEU3 LOC121047418 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC120840780|UniProtKB=A0ACM8EQ21 A0ACM8EQ21 LOC120840780 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120843672|UniProtKB=A0ACM8EXQ9 A0ACM8EXQ9 LOC120843672 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331570|UniProtKB=A0ACM8F8I1 A0ACM8F8I1 LOC115331570 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121045825|UniProtKB=A0ACM8FD87 A0ACM8FD87 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8025102|UniProtKB=A0ACM8DQ46 A0ACM8DQ46 Sec6 PTHR21292:SF1 EXOCYST COMPLEX COMPONENT SEC6-RELATED EXOCYST COMPLEX COMPONENT 3 SNARE binding#GO:0000149;binding#GO:0005488;protein binding#GO:0005515 secretion by cell#GO:0032940;exocytosis#GO:0006887;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;cytoplasm#GO:0005737;exocyst#GO:0000145;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;cell cortex#GO:0005938 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8042675|UniProtKB=A0ACM8DMX6 A0ACM8DMX6 LOC8042675 PTHR20884:SF8 GDP-D-GLUCOSE PHOSPHORYLASE 1 GDP-D-GLUCOSE PHOSPHORYLASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;response to stress#GO:0006950;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;glucose metabolic process#GO:0006006 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121045679|UniProtKB=A0ACM8FC34 A0ACM8FC34 LOC121045679 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846076|UniProtKB=A0ACM8F1H8 A0ACM8F1H8 LOC120846076 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121048000|UniProtKB=A0ACM8FHC7 A0ACM8FHC7 LOC121048000 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120851069|UniProtKB=A0ACM8FA10 A0ACM8FA10 LOC120851069 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8052442|UniProtKB=A0ACM8DLQ3 A0ACM8DLQ3 AIF PTHR43557:SF4 APOPTOSIS-INDUCING FACTOR 1 APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H#GO:0016651;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;programmed cell death#GO:0012501;cellular process#GO:0009987;apoptotic process#GO:0006915;cell death#GO:0008219;establishment of localization in cell#GO:0051649;mitochondrial transport#GO:0006839;mitochondrial protein import pathway#GO:7770058 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176 Apoptosis signaling pathway#P00006>AIF#P00286 IXOSC|EnsemblGenome=LOC8031240|UniProtKB=A0ACM8DI32 A0ACM8DI32 LOC8031240 PTHR43170:SF5 GMP REDUCTASE GMP REDUCTASE oxidoreductase#PC00176;reductase#PC00198 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 IXOSC|EnsemblGenome=LOC115325376|UniProtKB=A0ACM8E4R9 A0ACM8E4R9 eff PTHR24068:SF567 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME-RELATED catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 IXOSC|EnsemblGenome=LOC121836195|UniProtKB=A0ACM8FYS8 A0ACM8FYS8 LOC121836195 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036484|UniProtKB=A0ACM8DHH7 A0ACM8DHH7 LOC8036484 PTHR14119:SF17 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8053599|UniProtKB=A0ACM8EMG7 A0ACM8EMG7 LOC8053599 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121833257|UniProtKB=A0ACM8FK54 A0ACM8FK54 LOC121833257 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120845793|UniProtKB=A0ACM8F0L1 A0ACM8F0L1 LOC120845793 PTHR10151:SF114 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE C27A7.3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121838214|UniProtKB=A0ACM8G780 A0ACM8G780 LOC121838214 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315498|UniProtKB=A0ACM8F2G8 A0ACM8F2G8 LOC115315498 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152 IXOSC|EnsemblGenome=LOC8039510|UniProtKB=A0ACM8DVZ0 A0ACM8DVZ0 LOC8039510 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8039332|UniProtKB=A0ACM8ED75 A0ACM8ED75 LOC8039332 PTHR46197:SF3 PROTEIN ABHD14B-LIKE AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121835215|UniProtKB=A0ACM8FSW7 A0ACM8FSW7 LOC121835215 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042804|UniProtKB=A0ACM8DU09 A0ACM8DU09 LOC8042804 PTHR39158:SF1 OS08G0560600 PROTEIN DNAJ HEAT SHOCK PROTEIN FAMILY (HSP40) MEMBER C28 IXOSC|EnsemblGenome=LOC115314277|UniProtKB=A0ACM8DU39 A0ACM8DU39 LOC115314277 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8038627|UniProtKB=A0ACM8DK89 A0ACM8DK89 LOC8038627 PTHR13077:SF6 SELENOPROTEIN F SELENOPROTEIN F oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;endoplasmic reticulum lumen#GO:0005788;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8033710|UniProtKB=A0ACM8DI76 A0ACM8DI76 LOC8033710 PTHR43818:SF11 BCDNA.GH03377 BCDNA.GH03377 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8051182|UniProtKB=A0ACM8DLY8 A0ACM8DLY8 Drep4 PTHR13067:SF2 CASPASE-ACTIVATED DNASE DNAATION FACTOR-RELATED PROTEIN 4 nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 catabolic process#GO:0009056;apoptotic process#GO:0006915;cell death#GO:0008219;execution phase of apoptosis#GO:0097194;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;nucleobase-containing compound catabolic process#GO:0034655;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>CAD#P00618 IXOSC|EnsemblGenome=LOC8041033|UniProtKB=A0ACM8DWD0 A0ACM8DWD0 LOC8041033 PTHR24252:SF46 ACROSIN-RELATED ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8044068|UniProtKB=A0ACM8EAZ3 A0ACM8EAZ3 LOC8044068 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115316601|UniProtKB=A0ACM8EQ35 A0ACM8EQ35 Mys45A PTHR12730:SF0 HSDA/SDA1-RELATED PROTEIN SDA1 HOMOLOG ribonucleoprotein complex biogenesis#GO:0022613;establishment of organelle localization#GO:0051656;ribosomal large subunit export from nucleus#GO:0000055;nuclear export#GO:0051168;nuclear transport#GO:0051169;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;ribosomal large subunit biogenesis#GO:0042273;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component biogenesis#GO:0044085;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120839020|UniProtKB=A0ACM8ELC2 A0ACM8ELC2 LOC120839020 PTHR24346:SF51 MAP/MICROTUBULE AFFINITY-REGULATING KINASE PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of polysaccharide metabolic process#GO:0032881;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;signal transduction#GO:0007165;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of carbohydrate biosynthetic process#GO:0043255;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121838170|UniProtKB=A0ACM8G6Z2 A0ACM8G6Z2 LOC121838170 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120844659|UniProtKB=A0ACM8F0B0 A0ACM8F0B0 LOC120844659 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120837214|UniProtKB=A0ACM8EGF9 A0ACM8EGF9 LOC120837220 PTHR11426:SF265 HISTONE H3 HISTONE H3.2 chromosome localization#GO:0050000;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;membraneless organelle assembly#GO:0140694;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;kinetochore assembly#GO:0051382;organelle localization#GO:0051640;nuclear division#GO:0000280;organelle assembly#GO:0070925 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 IXOSC|EnsemblGenome=LOC120846159|UniProtKB=A0ACM8FI43 A0ACM8FI43 LOC120846159 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051753|UniProtKB=A0ACM8F1U5 A0ACM8F1U5 LOC8051753 PTHR22803:SF124 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED ACCESSORY GLAND PROTEIN ACP29AB-RELATED membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8033629|UniProtKB=A0ACM8G7R7 A0ACM8G7R7 yki PTHR17616:SF8 YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER YES-ASSOCIATED PROTEIN HOMOLOG 1 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;hippo signaling#GO:0035329;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of transcription by RNA polymerase II#GO:0045944 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115320958|UniProtKB=A0ACM8EME8 A0ACM8EME8 LOC115320958 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC115309467|UniProtKB=A0ACM8DNU6 A0ACM8DNU6 LOC115309467 PTHR21093:SF2 DIVERGENT PROTEIN KINASE DOMAIN 1C-RELATED DIVERGENT PROTEIN KINASE DOMAIN 1C IXOSC|EnsemblGenome=LOC8044049|UniProtKB=A0ACM8DN21 A0ACM8DN21 LOC8044049 PTHR13413:SF0 YLP MOTIF CONTAINING PROTEIN NUCLEAR PROTEIN ZAP YLP MOTIF-CONTAINING PROTEIN 1 regulation of telomere maintenance#GO:0032204;regulation of chromosome organization#GO:0033044;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of DNA metabolic process#GO:0051052;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115327103|UniProtKB=A0ACM8F0S0 A0ACM8F0S0 LOC115327103 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120850668|UniProtKB=A0ACM8FPY2 A0ACM8FPY2 LOC120850668 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841194|UniProtKB=A0ACM8ER14 A0ACM8ER14 LOC120841194 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841354|UniProtKB=A0ACM8ERL4 A0ACM8ERL4 LOC120841354 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8029116|UniProtKB=A0ACM8F5S4 A0ACM8F5S4 LOC8029116 PTHR47959:SF30 ATP-DEPENDENT RNA HELICASE RHLE-RELATED ATP-DEPENDENT RNA HELICASE DDX47-RELATED RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC120849662|UniProtKB=A0ACM8F887 A0ACM8F887 LOC120849662 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8041738|UniProtKB=A0ACM8E4S5 A0ACM8E4S5 wal PTHR43153:SF1 ELECTRON TRANSFER FLAVOPROTEIN ALPHA ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8032832|UniProtKB=A0ACM8EGY7 A0ACM8EGY7 LOC8032832 PTHR18916:SF95 DYNACTIN 1-RELATED MICROTUBULE-BINDING DYNACTIN SUBUNIT 1 nuclear migration#GO:0007097;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;localization#GO:0051179;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;spindle localization#GO:0051653;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;cytoskeleton organization#GO:0007010;transport#GO:0006810;intracellular transport#GO:0046907;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;cellular component organization or biogenesis#GO:0071840;establishment of mitotic spindle orientation#GO:0000132;establishment of localization#GO:0051234 spindle pole#GO:0000922;chromosome#GO:0005694;kinetochore#GO:0000776;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;axon#GO:0030424;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;neuron projection#GO:0043005;supramolecular complex#GO:0099080;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;spindle#GO:0005819;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228 chaperone#PC00072 Huntington disease#P00029>Dynactin#P00781 IXOSC|EnsemblGenome=LOC115325483|UniProtKB=A0ACM8E6A2 A0ACM8E6A2 LOC115325483 PTHR23159:SF31 CENTROSOMAL PROTEIN 2 CENTROSOMAL PROTEIN 135KDA, ISOFORM B chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8041213|UniProtKB=A0ACM8DKN0 A0ACM8DKN0 LOC8041213 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC121047064|UniProtKB=A0ACM8FGD1 A0ACM8FGD1 LOC121047064 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8023973|UniProtKB=A0ACM8FLM1 A0ACM8FLM1 LOC8023973 PTHR11537:SF289 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAB channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;action potential#GO:0001508;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813 membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241;ion channel#PC00133 IXOSC|EnsemblGenome=LOC121835800|UniProtKB=A0ACM8FX02 A0ACM8FX02 LOC121835800 PTHR10890:SF33 CYSTEINYL-TRNA SYNTHETASE CYSTEINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8025178|UniProtKB=A0ACM8EDM5 A0ACM8EDM5 Mtp PTHR13024:SF0 MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN, LARGE SUBUNIT MICROSOMAL TRIACYLGLYCEROL TRANSFER PROTEIN protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;lipoprotein metabolic process#GO:0042157;primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987 basal part of cell#GO:0045178;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;plasma membrane region#GO:0098590;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794 transporter#PC00227 IXOSC|EnsemblGenome=LOC115319821|UniProtKB=A0ACM8E098 A0ACM8E098 LOC115319821 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031767|UniProtKB=A0ACM8FSD7 A0ACM8FSD7 LOC8031767 PTHR24198:SF196 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ZU5 DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8041618|UniProtKB=A0ACM8E5X8 A0ACM8E5X8 LOC8041618 PTHR24412:SF480 KELCH PROTEIN KELCH-LIKE PROTEIN 8 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;transferase complex#GO:1990234;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115313285|UniProtKB=A0ACM8FIE9 A0ACM8FIE9 LOC115313285 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8028604|UniProtKB=A0ACM8G8E4 A0ACM8G8E4 LOC8028604 PTHR24413:SF229 SPECKLE-TYPE POZ PROTEIN GH01369P binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of proteolysis#GO:0030162 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8053180|UniProtKB=A0ACM8EUV1 A0ACM8EUV1 LOC8053180 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120838376|UniProtKB=A0ACM8EKF2 A0ACM8EKF2 LOC120838376 PTHR24073:SF941 DRAB5-RELATED RAS-RELATED PROTEIN RAB-20 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;endocytosis#GO:0006897;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endocytic vesicle#GO:0030139;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC120844046|UniProtKB=A0ACM8EXN9 A0ACM8EXN9 LOC120844046 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115316316|UniProtKB=A0ACM8EYV8 A0ACM8EYV8 LOC115316316 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115319080|UniProtKB=A0ACM8DZJ6 A0ACM8DZJ6 LOC115319080 PTHR12995:SF4 FI21814P1 FI21814P1 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120837936|UniProtKB=A0ACM8FQT2 A0ACM8FQT2 LOC120837936 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313971|UniProtKB=A0ACM8F2Z6 A0ACM8F2Z6 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8033180|UniProtKB=A0ACM8G2E6 A0ACM8G2E6 LOC8033180 PTHR24049:SF22 CRUMBS FAMILY MEMBER DELTA-LIKE PROTEIN establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cell-cell adhesion#GO:0098609;heterophilic cell-cell adhesion#GO:0007157;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8052318|UniProtKB=A0ACM8F7L8 A0ACM8F7L8 LOC8052318 PTHR21229:SF2 LUNG SEVEN TRANSMEMBRANE RECEPTOR RE59932P membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8039340|UniProtKB=A0ACM8E482 A0ACM8E482 LOC8039340 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8043099|UniProtKB=A0ACM8EDR8 A0ACM8EDR8 LOC8043099 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8035854|UniProtKB=A0ACM8DWV3 A0ACM8DWV3 PTHR21381:SF3 ZGC:162297 SGC REGION PROTEIN SGCQ-RELATED IXOSC|EnsemblGenome=LOC120843879|UniProtKB=A0ACM8EY47 A0ACM8EY47 LOC120843879 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC120842120|UniProtKB=A0ACM8EU73 A0ACM8EU73 l(2)05287 PTHR44215:SF1 WD REPEAT-CONTAINING PROTEIN 75 WD REPEAT-CONTAINING PROTEIN 75 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase I#GO:0006356;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase I#GO:0045943;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8028853|UniProtKB=A0ACM8EFD1 A0ACM8EFD1 LOC8028853 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043535|UniProtKB=A0ACM8E4E5 A0ACM8E4E5 LOC8043535 PTHR13693:SF105 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE 2-AMINO-3-KETOBUTYRATE COENZYME A LIGASE, MITOCHONDRIAL cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transaminase#PC00216 IXOSC|EnsemblGenome=LOC121838456|UniProtKB=A0ACM8G8B7 A0ACM8G8B7 LOC121838456 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121833966|UniProtKB=A0ACM8FNS4 A0ACM8FNS4 PTHR35617:SF4 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN TYR RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040281|UniProtKB=A0ACM8E043 A0ACM8E043 LOC8040281 PTHR13198:SF4 RING FINGER PROTEIN 25 E3 UBIQUITIN-PROTEIN LIGASE RNF25 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;organelle organization#GO:0006996;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein catabolic process#GO:0030163;translation#GO:0006412;modification-dependent macromolecule catabolic process#GO:0043632;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;rescue of stalled cytosolic ribosome#GO:0072344;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056;protein biosynthetic process#GO:0160307 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121837703|UniProtKB=A0ACM8G4T3 A0ACM8G4T3 LOC121837703 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835994|UniProtKB=A0ACM8FWP4 A0ACM8FWP4 LOC121835994 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115316931|UniProtKB=A0ACM8FVH1 A0ACM8FVH1 LOC115316931 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8025989|UniProtKB=A0ACM8FJY1 A0ACM8FJY1 LOC8025989 PTHR13468:SF1 DEK PROTEIN PROTEIN DEK binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;regulation of DNA repair#GO:0006282;regulation of response to stimulus#GO:0048583;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of cellular response to stress#GO:0080135;regulation of double-strand break repair#GO:2000779;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8027716|UniProtKB=A0ACM8DVL7 A0ACM8DVL7 LOC8027716 PTHR14942:SF21 U11/U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN U11_U12 SMALL NUCLEAR RIBONUCLEOPROTEIN 25 KDA PROTEIN intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;U12-type spliceosomal complex#GO:0005689;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 IXOSC|EnsemblGenome=LOC8028278|UniProtKB=A0ACM8DJN6 A0ACM8DJN6 LOC8028278 PTHR24056:SF472 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120842439|UniProtKB=A0ACM8ETU0 A0ACM8ETU0 LOC120842439 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029722|UniProtKB=A0ACM8E305 A0ACM8E305 Wdfy2 PTHR46189:SF1 LD41958P LD41958P endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;endosome#GO:0005768;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120847417|UniProtKB=A0ACM8FYR2 A0ACM8FYR2 LOC120847417 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8024830|UniProtKB=A0ACM8DT21 A0ACM8DT21 LOC8024830 PTHR42908:SF6 TRANSLATION ELONGATION FACTOR-RELATED 116 KDA U5 SMALL NUCLEAR RIBONUCLEOPROTEIN COMPONENT translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;snRNA binding#GO:0017069;hydrolase activity#GO:0016787;RNA binding#GO:0003723;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleic acid binding#GO:0003676;GTPase activity#GO:0003924 protein biosynthetic process#GO:0160307;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein metabolic process#GO:0019538;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;translation#GO:0006412;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational elongation#GO:0006414;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC115318318|UniProtKB=A0ACM8ENI3 A0ACM8ENI3 LOC115318318 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8052758|UniProtKB=A0ACM8EY12 A0ACM8EY12 LOC8052758 PTHR31102:SF1 FAMILY NOT NAMED SOLUTE CARRIER FAMILY 9 MEMBER B2 IXOSC|EnsemblGenome=LOC8039718|UniProtKB=A0ACM8DZ19 A0ACM8DZ19 qless PTHR12001:SF89 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS1 prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 isoprenoid metabolic process#GO:0006720;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;ubiquinone biosynthetic process#GO:0006744;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262 Cholesterol biosynthesis#P00014>Dimethylallyl trans-transferase#P00490 IXOSC|EnsemblGenome=LOC8026943|UniProtKB=A0ACM8DIK9 A0ACM8DIK9 Rab21 PTHR24073:SF1235 DRAB5-RELATED RAS-RELATED PROTEIN RAB-21 ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;protein transport#GO:0015031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 G-protein#PC00020;small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120840336|UniProtKB=A0ACM8EP79 A0ACM8EP79 LOC120840336 PTHR10629:SF61 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 binding#GO:0005488;nucleic acid binding#GO:0003676;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;DNA binding#GO:0003677;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on DNA#GO:0140097 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009;DNA methyltransferase#PC00013 IXOSC|EnsemblGenome=LOC8039494|UniProtKB=A0ACM8FQX1 A0ACM8FQX1 LOC8039494 PTHR20910:SF1 AGAP001623-PA RELATED TO SOD IXOSC|EnsemblGenome=LOC8035968|UniProtKB=A0ACM8DML8 A0ACM8DML8 LOC8035968 PTHR11069:SF23 GLUCOSYLCERAMIDASE LYSOSOMAL ACID GLUCOSYLCERAMIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 ceramide metabolic process#GO:0006672;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042 IXOSC|EnsemblGenome=LOC8029886|UniProtKB=A0ACM8EB72 A0ACM8EB72 LOC8029886 PTHR11409:SF43 ADENOSINE DEAMINASE ADENOSINE DEAMINASE catalytic activity#GO:0003824;adenosine deaminase activity#GO:0004000;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;nucleoside catabolic process#GO:0009164;purine nucleoside metabolic process#GO:0042278;purine-containing compound biosynthetic process#GO:0072522;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;nucleobase metabolic process#GO:0009112;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;small molecule biosynthetic process#GO:0044283;purine nucleobase metabolic process#GO:0006144;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 deaminase#PC00088 Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807;Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811 IXOSC|EnsemblGenome=LOC8031759|UniProtKB=A0ACM8E0T8 A0ACM8E0T8 LOC8031759 PTHR13180:SF4 SMALL MEMBRANE PROTEIN-RELATED TRANSMEMBRANE PROTEIN 50A endosomal transport#GO:0016197;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147 endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120840799|UniProtKB=A0ACM8EQ38 A0ACM8EQ38 LOC120840799 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 hydrolase activity#GO:0016787;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC115316364|UniProtKB=A0ACM8DWD6 A0ACM8DWD6 PTHR24055:SF616 MITOGEN-ACTIVATED PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 transport#GO:0006810;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;organelle assembly#GO:0070925;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;intraciliary transport#GO:0042073;regulation of cellular process#GO:0050794;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cell projection assembly#GO:0030031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;cellular localization#GO:0051641;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cilium assembly#GO:0060271;signaling#GO:0023052;response to stimulus#GO:0050896;cell projection organization#GO:0030030 cilium#GO:0005929;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120836157|UniProtKB=A0ACM8G825 A0ACM8G825 LOC120836157 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115327359|UniProtKB=A0ACM8EI80 A0ACM8EI80 LOC115327359 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120842891|UniProtKB=A0ACM8EUS4 A0ACM8EUS4 LOC120842891 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846300|UniProtKB=A0ACM8F1Z7 A0ACM8F1Z7 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121833581|UniProtKB=A0ACM8FKG4 A0ACM8FKG4 LOC121833581 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025600|UniProtKB=A0ACM8DSC2 A0ACM8DSC2 LOC8025600 PTHR12729:SF6 TRNA(HIS) GUANYLYLTRANSFERASE-RELATED TRNA(HIS) GUANYLYLTRANSFERASE-RELATED catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC8038525|UniProtKB=A0ACM8DZ80 A0ACM8DZ80 PTHR10164:SF4 ISLET CELL AUTOANTIGEN 1 GH23156P molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 regulation of secretion#GO:0051046;cellular component organization or biogenesis#GO:0071840;regulation of transport#GO:0051049;regulation of localization#GO:0032879;membrane organization#GO:0061024;biological regulation#GO:0065007;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;secretory vesicle#GO:0099503;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;secretory granule#GO:0030141;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8040362|UniProtKB=A0ACM8DSN3 A0ACM8DSN3 LOC8040362 PTHR32546:SF25 G-PROTEIN COUPLED RECEPTOR 158-RELATED MIP05539P transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121835842|UniProtKB=A0ACM8FW12 A0ACM8FW12 LOC121835842 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026591|UniProtKB=A0ACM8G039 A0ACM8G039 LOC8026591 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115315634|UniProtKB=A0ACM8FDV0 A0ACM8FDV0 LOC115315634 PTHR23338:SF16 SMALL NUCLEAR RIBONUCLEOPROTEIN SM U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM4 RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;mRNA processing#GO:0006397;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organelle assembly#GO:0070925;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;P-body assembly#GO:0033962;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774 ribonucleoprotein complex#GO:1990904;P-body#GO:0000932;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U6 snRNP#GO:0005688;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120843491|UniProtKB=A0ACM8EW96 A0ACM8EW96 LOC120843491 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051982|UniProtKB=A0ACM8E499 A0ACM8E499 meigo PTHR10778:SF10 SOLUTE CARRIER FAMILY 35 MEMBER B SOLUTE CARRIER FAMILY 35 MEMBER B1 carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;organophosphate ester transmembrane transporter activity#GO:0015605;UDP-galactose transmembrane transporter activity#GO:0005459;nucleobase-containing compound transmembrane transporter activity#GO:0015932;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleotide-sugar transmembrane transport#GO:0015780;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115330934|UniProtKB=A0ACM8EBF5 A0ACM8EBF5 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030344|UniProtKB=A0ACM8DNC5 A0ACM8DNC5 Ddx1 PTHR24031:SF307 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX1 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;cytosol#GO:0005829;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115328490|UniProtKB=A0ACM8ELA3 A0ACM8ELA3 LOC115328490 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8037703|UniProtKB=A0ACM8DK53 A0ACM8DK53 LOC8037703 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8025164|UniProtKB=A0ACM8FNH6 A0ACM8FNH6 PTHR23222:SF0 PROHIBITIN PROHIBITIN 1 IXOSC|EnsemblGenome=LOC121836025|UniProtKB=A0ACM8FY12 A0ACM8FY12 LOC121836025 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC8028960|UniProtKB=A0ACM8E0X4 A0ACM8E0X4 BBS5 PTHR21351:SF0 BARDET-BIEDL SYNDROME PROTEIN 5 BBSOME COMPLEX MEMBER BBS5 binding#GO:0005488;phospholipid binding#GO:0005543;phosphatidylinositol phosphate binding#GO:1901981;phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289 cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;BBSome#GO:0034464;intracellular membraneless organelle#GO:0043232;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=ISCI005387|UniProtKB=Q8MVC4 Q8MVC4 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC121835923|UniProtKB=A0ACM8FXH9 A0ACM8FXH9 LOC121835923 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular response to stimulus#GO:0051716;cellular process#GO:0009987;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115320690|UniProtKB=A0ACM8G8V6 A0ACM8G8V6 LOC115320690 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC8052694|UniProtKB=A0ACM8DTJ2 A0ACM8DTJ2 PTHR45752:SF209 LEUCINE-RICH REPEAT-CONTAINING LEUCINE-RICH REPEAT PROTEIN SOC-2 HOMOLOG signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;intracellular signal transduction#GO:0035556;regulation of Ras protein signal transduction#GO:0046578;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120839591|UniProtKB=A0ACM8FSV5 A0ACM8FSV5 LOC120839591 PTHR34008:SF2 REPETITIVE PROLINE-RICH CELL WALL PROTEIN 1 REPETITIVE PROLINE-RICH CELL WALL PROTEIN 1 IXOSC|EnsemblGenome=LOC121836653|UniProtKB=A0ACM8G0S5 A0ACM8G0S5 LOC121836653 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115315555|UniProtKB=A0ACM8FXE0 A0ACM8FXE0 LOC115315555 PTHR11447:SF16 CELLULAR TUMOR ANTIGEN P53 P53, ISOFORM B RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell death#GO:0008219;cellular response to stimulus#GO:0051716;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;programmed cell death#GO:0012501;regulation of apoptotic process#GO:0042981;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;intrinsic apoptotic signaling pathway#GO:0097193;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785 P53-like transcription factor#PC00253;gene-specific transcriptional regulator#PC00264 Huntington disease#P00029>p53#P00797 IXOSC|EnsemblGenome=LOC8029309|UniProtKB=A0ACM8ETX5 A0ACM8ETX5 LOC8029309 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8035752|UniProtKB=A0ACM8DPG1 A0ACM8DPG1 LOC8035752 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8040797|UniProtKB=A0ACM8EBY5 A0ACM8EBY5 LOC8040797 PTHR43807:SF23 FI04487P FI04487P catalytic activity#GO:0003824;transferase activity#GO:0016740;transaminase activity#GO:0008483 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transferase#PC00220;transaminase#PC00216;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121046439|UniProtKB=A0ACM8FE50 A0ACM8FE50 LOC121046439 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035069|UniProtKB=A0ACM8E8D6 A0ACM8E8D6 RSG7 PTHR45746:SF6 LP21163P LP21163P enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS#P00704;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>RGS#P00731 IXOSC|EnsemblGenome=LOC8037095|UniProtKB=A0ACM8EA52 A0ACM8EA52 Mcm5 PTHR11630:SF42 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR MCM5 DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;response to stress#GO:0006950;double-strand break repair via break-induced replication#GO:0000727;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC8042343|UniProtKB=A0ACM8E4T6 A0ACM8E4T6 LOC8042343 PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051 membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC8026419|UniProtKB=A0ACM8DHR6 A0ACM8DHR6 LOC8026419 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120840419|UniProtKB=A0ACM8ENJ7 A0ACM8ENJ7 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC115322150|UniProtKB=A0ACM8FDW2 A0ACM8FDW2 grp PTHR24346:SF107 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE CHK1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115316152|UniProtKB=A0ACM8FWW8 A0ACM8FWW8 LOC115316152 PTHR48480:SF2 FAMILY NOT NAMED XAA-PRO DIPEPTIDASE IXOSC|EnsemblGenome=LOC8028553|UniProtKB=A0ACM8DXH9 A0ACM8DXH9 D2hgdh PTHR43716:SF6 D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL D-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8053088|UniProtKB=A0ACM8DLM7 A0ACM8DLM7 LOC8053088 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8041348|UniProtKB=A0ACM8DWL9 A0ACM8DWL9 Tao PTHR48015:SF50 SERINE/THREONINE-PROTEIN KINASE TAO SERINE_THREONINE-PROTEIN KINASE SULU protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121836537|UniProtKB=A0ACM8FZZ6 A0ACM8FZZ6 LOC121836537 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030821|UniProtKB=A0ACM8G2U8 A0ACM8G2U8 LOC8030821 PTHR24086:SF15 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NUCLEAR HORMONE RECEPTOR FTZ-F1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of macromolecule biosynthetic process#GO:0010556;response to hormone#GO:0009725;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;signal transduction#GO:0007165;tissue development#GO:0009888;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115325355|UniProtKB=A0ACM8FWH0 A0ACM8FWH0 LOC115325355 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115308168|UniProtKB=A0ACM8DXV3 A0ACM8DXV3 LOC115308168 PTHR11406:SF0 PHOSPHOGLYCERATE KINASE PHOSPHOGLYCERATE KINASE anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;phosphoglycerate kinase activity#GO:0004618;phosphotransferase activity, carboxyl group as acceptor#GO:0016774;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotide binding#GO:0000166;binding#GO:0005488;ATP binding#GO:0005524;nucleoside phosphate binding#GO:1901265;transferase activity#GO:0016740;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;kinase activity#GO:0016301;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;oxoacid metabolic process#GO:0043436;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;ribonucleoside diphosphate metabolic process#GO:0009185;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;small molecule biosynthetic process#GO:0044283;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;cellular respiration#GO:0045333;organophosphate catabolic process#GO:0046434;ribonucleoside diphosphate catabolic process#GO:0009191;purine nucleotide catabolic process#GO:0006195;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;nucleoside diphosphate catabolic process#GO:0009134;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;ADP catabolic process#GO:0046032;carbohydrate biosynthetic process#GO:0016051;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;pyruvate metabolic process#GO:0006090;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;purine nucleotide metabolic process#GO:0006163;monocarboxylic acid metabolic process#GO:0032787;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;organophosphate metabolic process#GO:0019637;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;pyridine-containing compound metabolic process#GO:0072524;nucleoside diphosphate metabolic process#GO:0009132;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate catabolic process#GO:1901292;purine nucleoside triphosphate metabolic process#GO:0009144;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 carbohydrate kinase#PC00065 Glycolysis#P00024>Phosphoglycerate kinase#P00671 IXOSC|EnsemblGenome=LOC115317385|UniProtKB=A0ACM8DWZ5 A0ACM8DWZ5 LOC115317385 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115331287|UniProtKB=A0ACM8F706 A0ACM8F706 LOC115331287 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120848465|UniProtKB=A0ACM8F5U2 A0ACM8F5U2 LOC120848465 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8051197|UniProtKB=A0ACM8DP74 A0ACM8DP74 Scm PTHR12247:SF132 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SCM protein binding#GO:0005515;chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115323542|UniProtKB=A0ACM8EQU7 A0ACM8EQU7 LOC115323542 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120841163|UniProtKB=A0ACM8ER89 A0ACM8ER89 LOC120841163 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121834731|UniProtKB=A0ACM8FR91 A0ACM8FR91 LOC121834731 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8031306|UniProtKB=A0ACM8ENA7 A0ACM8ENA7 LOC8031306 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC8036051|UniProtKB=A0ACM8DRM1 A0ACM8DRM1 Pi3K21B PTHR10155:SF10 PHOSPHATIDYLINOSITOL 3-KINASE REGULATORY SUBUNIT PI3K21B, ISOFORM B enzyme regulator activity#GO:0030234;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772 response to oxygen-containing compound#GO:1901700;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;cellular response to chemical stimulus#GO:0070887;response to nitrogen compound#GO:1901698;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;response to insulin#GO:0032868;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;cellular response to peptide hormone stimulus#GO:0071375;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;response to hormone#GO:0009725;response to peptide hormone#GO:0043434;biological regulation#GO:0065007;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221 extrinsic component of membrane#GO:0019898;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;membrane#GO:0016020;membrane protein complex#GO:0098796 kinase modulator#PC00140 Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway feedback loops 2#P04398>PI3K#P04661;p53 pathway#P00059>PI3K#P04609;Angiogenesis#P00005>PI3K#P00236;VEGF signaling pathway#P00056>PI3K#P01413;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Integrin signalling pathway#P00034>PI3K#P00936 IXOSC|EnsemblGenome=LOC8039585|UniProtKB=A0ACM8DKC2 A0ACM8DKC2 PTHR11937:SF155 ACTIN ACTIN-RELATED PROTEIN 1 structural molecule activity#GO:0005198;protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;structural constituent of cytoskeleton#GO:0005200;cytoskeletal adaptor activity#GO:0008093 microtubule-based process#GO:0007017;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;transport#GO:0006810;intracellular transport#GO:0046907;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;localization#GO:0051179;microtubule-based transport#GO:0099111;organelle localization#GO:0051640;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;nuclear migration#GO:0007097 organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin and actin related protein#PC00039 Nicotinic acetylcholine receptor signaling pathway#P00044>Actin#P01090 IXOSC|EnsemblGenome=LOC8023113|UniProtKB=A0ACM8F2Q7 A0ACM8F2Q7 tweek PTHR31640:SF1 TRANSMEMBRANE PROTEIN KIAA1109 BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 1 localization#GO:0051179;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;cellular localization#GO:0051641;establishment of localization#GO:0051234;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;synaptic vesicle endocytosis#GO:0048488;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC120838099|UniProtKB=A0ACM8EJ12 A0ACM8EJ12 LOC120838099 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322655|UniProtKB=A0ACM8FBX1 A0ACM8FBX1 ND-15 PTHR21268:SF2 NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 5 GH23780P IXOSC|EnsemblGenome=LOC120850407|UniProtKB=A0ACM8FA41 A0ACM8FA41 LOC120850407 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115326958|UniProtKB=A0ACM8E775 A0ACM8E775 Bet3 PTHR13048:SF0 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 3 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 vesicle-mediated transport#GO:0016192;intra-Golgi vesicle-mediated transport#GO:0006891;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810 cis-Golgi network#GO:0005801;vesicle tethering complex#GO:0099023;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;TRAPP complex#GO:0030008;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytosol#GO:0005829;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8023923|UniProtKB=A0ACM8G0Z3 A0ACM8G0Z3 LOC8023923 PTHR10408:SF7 STEROL O-ACYLTRANSFERASE DIACYLGLYCEROL O-ACYLTRANSFERASE 1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 glycerolipid metabolic process#GO:0046486;triglyceride biosynthetic process#GO:0019432;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 Androgen/estrogene/progesterone biosynthesis#P02727>Cholesterol acyltransferase#P02829 IXOSC|EnsemblGenome=LOC8041825|UniProtKB=A0ACM8E1R5 A0ACM8E1R5 LOC8041825 PTHR13697:SF4 PHOSPHOFRUCTOKINASE ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;carbohydrate kinase activity#GO:0019200;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;catalytic activity#GO:0003824 pyridine-containing compound catabolic process#GO:0072526;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;small molecule catabolic process#GO:0044282;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;nicotinamide nucleotide metabolic process#GO:0046496;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;glucose metabolic process#GO:0006006;purine-containing compound catabolic process#GO:0072523;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031 cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065;kinase#PC00137;transferase#PC00220 Glycolysis#P00024>Phosphofructokinase-1#P00672 IXOSC|EnsemblGenome=LOC8025842|UniProtKB=A0ACM8EGG8 A0ACM8EGG8 Arc42 PTHR43884:SF42 ACYL-COA DEHYDROGENASE SHORT-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;short-chain fatty acid catabolic process#GO:0019626;lipid oxidation#GO:0034440 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121045675|UniProtKB=A0ACM8FC26 A0ACM8FC26 LOC121045675 PTHR24251:SF57 OVOCHYMASE-RELATED CUB DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8031171|UniProtKB=A0ACM8DI09 A0ACM8DI09 LOC8031171 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121833318|UniProtKB=A0ACM8FJ32 A0ACM8FJ32 LOC121833318 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8024809|UniProtKB=A0ACM8DIQ2 A0ACM8DIQ2 LOC8024809 PTHR11907:SF0 AMIDOPHOSPHORIBOSYLTRANSFERASE AMIDOPHOSPHORIBOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165 transferase#PC00220;metabolite interconversion enzyme#PC00262 De novo purine biosynthesis#P02738>Amidophosphoribosyl transferase#P02905 IXOSC|EnsemblGenome=LOC120849587|UniProtKB=A0ACM8F722 A0ACM8F722 LOC120849587 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC120849697|UniProtKB=A0ACM8FRH2 A0ACM8FRH2 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8024184|UniProtKB=A0ACM8ECS2 A0ACM8ECS2 LOC8024184 PTHR21964:SF13 BREAST CANCER METASTASIS-SUPPRESSOR 1 BRMS1 TRANSCRIPTIONAL REPRESSOR binding#GO:0005488;enzyme binding#GO:0019899;histone deacetylase binding#GO:0042826;protein binding#GO:0005515 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;chromosome#GO:0005694;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC121046317|UniProtKB=A0ACM8FER2 A0ACM8FER2 LOC121046317 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8024954|UniProtKB=A0ACM8FDK5 A0ACM8FDK5 LOC8024954 PTHR24372:SF82 GLYCOPROTEIN HORMONE RECEPTOR RICKETS G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8029809|UniProtKB=A0ACM8DIV5 A0ACM8DIV5 LOC8029809 PTHR43798:SF33 MONOACYLGLYCEROL LIPASE SERINE HYDROLASE-LIKE PROTEIN DDB_G0286239 membrane#GO:0016020;cellular anatomical structure#GO:0110165 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115330896|UniProtKB=A0ACM8ER99 A0ACM8ER99 LOC115330896 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8035307|UniProtKB=A0ACM8DJS6 A0ACM8DJS6 LOC8035307 PTHR18916:SF97 DYNACTIN 1-RELATED MICROTUBULE-BINDING TUBULIN-FOLDING COFACTOR B protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cytoplasmic microtubule organization#GO:0031122;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule plus-end#GO:0035371;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;cell periphery#GO:0071944;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;microtubule end#GO:1990752;cell cortex#GO:0005938 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8033226|UniProtKB=A0ACM8DZ30 A0ACM8DZ30 LOC8033226 PTHR34394:SF1 SIMILAR TO RIKEN CDNA 2310022B05 SIMILAR TO HUMAN CHROMOSOME 1 OPEN READING FRAME 198 IXOSC|EnsemblGenome=LOC8037283|UniProtKB=A0ACM8DMT5 A0ACM8DMT5 LOC8037283 PTHR21624:SF1 STEROL DESATURASE-RELATED PROTEIN ALKYLGLYCEROL MONOOXYGENASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120845266|UniProtKB=A0ACM8F082 A0ACM8F082 LOC120845266 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120838544|UniProtKB=A0ACM8EK14 A0ACM8EK14 LOC120838544 PTHR15502:SF7 CALCINEURIN-BINDING PROTEIN CABIN 1-RELATED CALCINEURIN-BINDING PROTEIN CABIN-1 transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;binding#GO:0005488;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 phosphatase inhibitor#PC00183 IXOSC|EnsemblGenome=LOC120844440|UniProtKB=A0ACM8EYD8 A0ACM8EYD8 LOC120844440 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121837458|UniProtKB=A0ACM8G4M1 A0ACM8G4M1 LOC121837458 PTHR10997:SF8 IMPORTIN-7, 8, 11 EXPORTIN-2 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein export from nucleus#GO:0006611;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to organelle#GO:0033365;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967;cytosol#GO:0005829 transporter#PC00227 IXOSC|EnsemblGenome=LOC8029942|UniProtKB=A0ACM8DP35 A0ACM8DP35 LOC8029942 PTHR15999:SF2 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8051825|UniProtKB=A0ACM8EBT6 A0ACM8EBT6 rogdi PTHR13618:SF1 LEUCINE ZIPPER CONTAINING TRANSCRIPTION FACTOR LZF1 PROTEIN ROGDI HOMOLOG cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC8052455|UniProtKB=A0ACM8E8L0 A0ACM8E8L0 LOC8052455 PTHR24073:SF471 DRAB5-RELATED RAS-RELATED PROTEIN RAB-24 catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031 membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC115325985|UniProtKB=A0ACM8F702 A0ACM8F702 LOC115325985 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC115318385|UniProtKB=A0ACM8EXD1 A0ACM8EXD1 LOC115318385 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037366|UniProtKB=A0ACM8FAP6 A0ACM8FAP6 Elk PTHR10217:SF637 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL EAG-LIKE K[+] CHANNEL, ISOFORM A potassium channel activity#GO:0005267;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007;potassium ion transmembrane transport#GO:0071805 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC115330529|UniProtKB=A0ACM8EVQ1 A0ACM8EVQ1 LOC115330529 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ligase activity#GO:0016874 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC115313215|UniProtKB=A0ACM8EZN0 A0ACM8EZN0 LOC115313215 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036629|UniProtKB=A0ACM8EM27 A0ACM8EM27 LOC8036629 PTHR11216:SF178 EH DOMAIN AT21416P protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 transport#GO:0006810;protein localization to cell periphery#GO:1990778;plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;endosomal transport#GO:0016197;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;establishment of localization in cell#GO:0051649;cell projection assembly#GO:0030031;cellular process#GO:0009987;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein localization to plasma membrane#GO:0072659;cilium assembly#GO:0060271;endocytic recycling#GO:0032456;cell projection organization#GO:0030030;endocytosis#GO:0006897 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;early endosome#GO:0005769;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;bounding membrane of organelle#GO:0098588;recycling endosome membrane#GO:0055038;organelle membrane#GO:0031090;recycling endosome#GO:0055037 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8024010|UniProtKB=A0ACM8EB18 A0ACM8EB18 LOC8024010 PTHR12081:SF18 TRANSCRIPTION FACTOR E2F TRANSCRIPTION FACTOR E2F2-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 p53 pathway feedback loops 2#P04398>E2F-1#P04652;Cell cycle#P00013>E2F#P00488;p53 pathway#P00059>E2F-1#P04627 IXOSC|EnsemblGenome=LOC121838176|UniProtKB=A0ACM8G6P6 A0ACM8G6P6 LOC121838176 PTHR19303:SF57 TRANSPOSON POGO TRANSPOSABLE ELEMENT WITH KRAB DOMAIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8051635|UniProtKB=A0ACM8F0Y2 A0ACM8F0Y2 LOC8051635 PTHR22957:SF352 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER WHACKED GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde transport, endosome to Golgi#GO:0042147 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC121835014|UniProtKB=A0ACM8FRZ5 A0ACM8FRZ5 LOC121838401 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120846638|UniProtKB=A0ACM8F2K5 A0ACM8F2K5 LOC120846638 PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8051053|UniProtKB=A0ACM8DXA4 A0ACM8DXA4 LOC8051053 PTHR11360:SF286 MONOCARBOXYLATE TRANSPORTER GH22266P-RELATED transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;monocarboxylic acid transport#GO:0015718;localization#GO:0051179;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8036136|UniProtKB=A0ACM8DJX1 A0ACM8DJX1 LOC8036136 PTHR21425:SF3 NICE-3 LIPID TRANSPORT AUXILIARY PROTEIN 1 IXOSC|EnsemblGenome=LOC120845349|UniProtKB=A0ACM8G403 A0ACM8G403 LOC120845349 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8042922|UniProtKB=A0ACM8DZ10 A0ACM8DZ10 LOC8042922 PTHR10379:SF14 MTG8 ETO EIGHT TWENTY ONE PROTEIN NERVY, ISOFORM D transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC115308684|UniProtKB=A0ACM8DMV2 A0ACM8DMV2 LOC115308684 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051109|UniProtKB=A0ACM8EAU5 A0ACM8EAU5 LOC8051109 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115311541|UniProtKB=A0ACM8DQU5 A0ACM8DQU5 LOC115311541 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8028687|UniProtKB=A0ACM8F7P7 A0ACM8F7P7 LOC8028687 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8053960|UniProtKB=A0ACM8G2A7 A0ACM8G2A7 l(2)37Cb PTHR18934:SF83 ATP-DEPENDENT RNA HELICASE PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8024817|UniProtKB=A0ACM8DVR7 A0ACM8DVR7 LOC8024817 PTHR21250:SF0 PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG PRE-RRNA-PROCESSING PROTEIN TSR2 HOMOLOG cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121838544|UniProtKB=A0ACM8G938 A0ACM8G938 LOC121838544 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC115330558|UniProtKB=A0ACM8G6M8 A0ACM8G6M8 LOC115330558 PTHR23235:SF190 KRUEPPEL-LIKE TRANSCRIPTION FACTOR SI:DKEY-210J14.3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8025987|UniProtKB=A0ACM8DY19 A0ACM8DY19 LOC8025987 PTHR46149:SF10 MIP08469P SSR-2 IXOSC|EnsemblGenome=LOC121835017|UniProtKB=A0ACM8FS05 A0ACM8FS05 LOC121835017 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8027147|UniProtKB=A0ACM8EPF6 A0ACM8EPF6 LOC8027147 PTHR23074:SF83 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein metabolic process#GO:0019538;cellular localization#GO:0051641;localization#GO:0051179;vacuole organization#GO:0007033;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;modification-dependent protein catabolic process#GO:0019941;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ubiquitin-dependent protein catabolic process#GO:0006511;endosomal transport#GO:0016197;macromolecule catabolic process#GO:0009057;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;vesicle-mediated transport#GO:0016192;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;organelle organization#GO:0006996;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649 intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC115324826|UniProtKB=A0ACM8G353 A0ACM8G353 LOC115324826 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8030727|UniProtKB=A0ACM8DHF6 A0ACM8DHF6 LOC8030727 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838213|UniProtKB=A0ACM8G747 A0ACM8G747 LOC121838213 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115312013|UniProtKB=A0ACM8DRT6 A0ACM8DRT6 LOC115312013 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120840976|UniProtKB=A0ACM8G6Z1 A0ACM8G6Z1 LOC120840976 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8027633|UniProtKB=A0ACM8EQ11 A0ACM8EQ11 LOC8027633 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC8027120|UniProtKB=A0ACM8E4I3 A0ACM8E4I3 LOC8027120 PTHR11614:SF198 PHOSPHOLIPASE-RELATED MONOGLYCERIDE LIPASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;membrane#GO:0016020 lipase#PC00143;phospholipase#PC00186 IXOSC|EnsemblGenome=LOC8033016|UniProtKB=A0ACM8DY34 A0ACM8DY34 LOC8033016 PTHR16019:SF5 SYNAPSE-ASSOCIATED PROTEIN BSD DOMAIN-CONTAINING PROTEIN 1 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120843154|UniProtKB=A0ACM8FPU6 A0ACM8FPU6 LOC120843154 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115315587|UniProtKB=A0ACM8DV14 A0ACM8DV14 LOC115315587 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115317105|UniProtKB=A0ACM8DXD2 A0ACM8DXD2 LOC115317105 PTHR24399:SF87 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8039897|UniProtKB=A0ACM8DKE7 A0ACM8DKE7 PTHR11679:SF2 VESICLE PROTEIN SORTING-ASSOCIATED SEC1 FAMILY DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;syntaxin binding#GO:0019905;binding#GO:0005488;SNARE binding#GO:0000149 localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8029129|UniProtKB=A0ACM8EJ20 A0ACM8EJ20 LOC8029129 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121834858|UniProtKB=A0ACM8FS28 A0ACM8FS28 LOC8038340 PTHR13166:SF7 PROTEIN C6ORF149 LYR MOTIF-CONTAINING PROTEIN 4 iron-sulfur cluster assembly#GO:0016226;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;sulfurtransferase complex#GO:1990228;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8031619|UniProtKB=A0ACM8FHZ7 A0ACM8FHZ7 LOC8031619 PTHR24228:SF63 B2 BRADYKININ RECEPTOR/ANGIOTENSIN II RECEPTOR G-PROTEIN COUPLED RECEPTOR MOODY transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115332134|UniProtKB=A0ACM8F039 A0ACM8F039 LOC115332134 PTHR43977:SF2 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN IXOSC|EnsemblGenome=LOC8036083|UniProtKB=A0ACM8E5J0 A0ACM8E5J0 LOC8036083 PTHR42776:SF4 SERINE PEPTIDASE S9 FAMILY MEMBER ACYLAMINO-ACID-RELEASING ENZYME hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8040037|UniProtKB=A0ACM8FC49 A0ACM8FC49 PTHR24406:SF44 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN C09F5.3-RELATED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8039041|UniProtKB=A0ACM8ESX1 A0ACM8ESX1 LOC8039041 PTHR42943:SF2 GLUTATHIONE S-TRANSFERASE KAPPA GLUTATHIONE S-TRANSFERASE KAPPA 1 transferase#PC00220 IXOSC|EnsemblGenome=LOC115326831|UniProtKB=A0ACM8E729 A0ACM8E729 LOC115326831 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033132|UniProtKB=A0ACM8EBY9 A0ACM8EBY9 LOC8033132 PTHR45842:SF12 SYNAPTIC ADHESION-LIKE MOLECULE SALM TIR DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8028476|UniProtKB=A0ACM8DGI9 A0ACM8DGI9 lsn PTHR12806:SF0 EAP30 SUBUNIT OF ELL COMPLEX VACUOLAR-SORTING PROTEIN SNF8 protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein transport#GO:0015031;cellular localization#GO:0051641;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;establishment of protein localization to vacuole#GO:0072666;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC8027906|UniProtKB=A0ACM8EDT6 A0ACM8EDT6 U2af50 PTHR23139:SF9 RNA-BINDING PROTEIN SPLICING FACTOR U2AF 65 KDA SUBUNIT single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723;pre-mRNA binding#GO:0036002;nucleic acid binding#GO:0003676;binding#GO:0005488 protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8028178|UniProtKB=A0ACM8G3W5 A0ACM8G3W5 LOC8028178 PTHR10877:SF183 POLYCYSTIN FAMILY MEMBER AT14535P-RELATED ion channel#PC00133 IXOSC|EnsemblGenome=LOC8051901|UniProtKB=A0ACM8DLX8 A0ACM8DLX8 LOC8051901 PTHR46362:SF1 GEM-ASSOCIATED PROTEIN 5 GEM-ASSOCIATED PROTEIN 5 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;Sm-like protein family complex#GO:0120114;SMN complex#GO:0032797;membrane-bounded organelle#GO:0043227;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8028254|UniProtKB=A0ACM8EB94 A0ACM8EB94 Nf-YA PTHR12632:SF122 TRANSCRIPTION FACTOR NF-Y ALPHA-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT ALPHA DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 IXOSC|EnsemblGenome=LOC120836251|UniProtKB=A0ACM8FBM8 A0ACM8FBM8 LOC120836251 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8052199|UniProtKB=A0ACM8DXZ0 A0ACM8DXZ0 LOC8052199 PTHR24012:SF796 RNA BINDING PROTEIN PROTEIN ALAN SHEPARD RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8036761|UniProtKB=A0ACM8E360 A0ACM8E360 LOC8036761 PTHR10997:SF7 IMPORTIN-7, 8, 11 IMPORTIN-11 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104 cytosol#GO:0005829;organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC8042903|UniProtKB=A0ACM8DRN5 A0ACM8DRN5 capt PTHR10652:SF26 ADENYLYL CYCLASE-ASSOCIATED PROTEIN ADENYLYL CYCLASE-ASSOCIATED PROTEIN enzyme binding#GO:0019899;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 developmental process#GO:0032502;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cell morphogenesis#GO:0000902 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8027295|UniProtKB=A0ACM8DIX1 A0ACM8DIX1 LOC8027295 PTHR10749:SF7 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA-RELATED cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 IXOSC|EnsemblGenome=ISCI005425|UniProtKB=Q4PM54 Q4PM54 RpL17 PTHR11593:SF10 60S RIBOSOMAL PROTEIN L17 LARGE RIBOSOMAL SUBUNIT PROTEIN UL22 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8033640|UniProtKB=A0ACM8DI59 A0ACM8DI59 LOC8033640 PTHR28366:SF1 CHROMOSOME 1 OPEN READING FRAME 131 40S SMALL SUBUNIT PROCESSOME ASSEMBLY FACTOR 1 IXOSC|EnsemblGenome=LOC120843464|UniProtKB=A0ACM8EW88 A0ACM8EW88 LOC120843464 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8034917|UniProtKB=A0ACM8EP45 A0ACM8EP45 LOC8034917 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115313452|UniProtKB=A0ACM8EUM1 A0ACM8EUM1 LOC115313593 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039584|UniProtKB=A0ACM8DKE9 A0ACM8DKE9 PTHR10412:SF11 MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE MANNOSYL-OLIGOSACCHARIDE GLUCOSIDASE glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 hydrolase#PC00121;glucosidase#PC00108 IXOSC|EnsemblGenome=LOC8051680|UniProtKB=A0ACM8E5M9 A0ACM8E5M9 LOC8051680 PTHR47039:SF1 INOSITOL POLYPHOSPHATE 5-PHOSPHATASE E INOSITOL POLYPHOSPHATE 5-PHOSPHATASE E nervous system process#GO:0050877;sensory perception#GO:0007600;sensory perception of mechanical stimulus#GO:0050954;system process#GO:0003008;intracellular protein localization#GO:0008104;localization#GO:0051179;macromolecule localization#GO:0033036;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;multicellular organismal process#GO:0032501;sensory perception of sound#GO:0007605 plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cilium#GO:0005929;ciliary base#GO:0097546 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8029019|UniProtKB=A0ACM8E146 A0ACM8E146 whd PTHR22589:SF31 CARNITINE O-ACYLTRANSFERASE CARNITINE O-PALMITOYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120838944|UniProtKB=A0ACM8G733 A0ACM8G733 LOC120838944 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8024474|UniProtKB=A0ACM8E9X4 A0ACM8E9X4 LOC8024474 PTHR10165:SF103 LIPID PHOSPHATE PHOSPHATASE FI04477P-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 dephosphorylation#GO:0016311;cell communication#GO:0007154;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphate-containing compound metabolic process#GO:0006796;cellular response to stimulus#GO:0051716;phospholipid dephosphorylation#GO:0046839;regulation of biological process#GO:0050789;lipid modification#GO:0030258;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121835329|UniProtKB=A0ACM8FUG6 A0ACM8FUG6 yip2 PTHR18919:SF175 ACETYL-COA C-ACYLTRANSFERASE 3-KETOACYL-COA THIOLASE, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740 monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8052458|UniProtKB=A0ACM8FCC3 A0ACM8FCC3 LOC8052458 PTHR12626:SF15 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation factor#PC00223 IXOSC|EnsemblGenome=LOC120843396|UniProtKB=A0ACM8FX67 A0ACM8FX67 LOC120843396 PTHR24246:SF61 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled adenosine receptor signaling pathway#GO:0001973;cell surface receptor signaling pathway#GO:0007166;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 IXOSC|EnsemblGenome=LOC8031543|UniProtKB=A0ACM8FZJ7 A0ACM8FZJ7 LOC8031543 PTHR23179:SF3 T-CELL ACTIVATION RHO GTPASE ACTIVATING PROTEIN-RELATED RHO GTPASE-ACTIVATING PROTEIN 20 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC8036617|UniProtKB=A0ACM8DSR3 A0ACM8DSR3 LOC8036617 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120839596|UniProtKB=A0ACM8EM29 A0ACM8EM29 LOC120839596 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120844702|UniProtKB=A0ACM8F0G6 A0ACM8F0G6 LOC120844702 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120850809|UniProtKB=A0ACM8G0W1 A0ACM8G0W1 LOC120850809 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8027415|UniProtKB=A0ACM8DT48 A0ACM8DT48 LOC8027415 PTHR10257:SF3 SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B WELL-ROUNDED, ISOFORM B phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;phosphatase activator activity#GO:0019211;protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;meiotic sister chromatid cohesion#GO:0051177 protein modifying enzyme#PC00260;protein phosphatase#PC00195 FGF signaling pathway#P00021>PP2A#P00629;Wnt signaling pathway#P00057>PP2A#P01438;EGF receptor signaling pathway#P00018>PP2A#P00547 IXOSC|EnsemblGenome=LOC121837464|UniProtKB=A0ACM8G3M0 A0ACM8G3M0 LOC121837464 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8034277|UniProtKB=A0ACM8DVP2 A0ACM8DVP2 LOC8034277 PTHR11132:SF558 SOLUTE CARRIER FAMILY 35 UDP-SUGAR TRANSPORTER UST74C carboxylic acid transmembrane transporter activity#GO:0046943;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nucleotide-sugar transmembrane transport#GO:0015780;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115324267|UniProtKB=A0ACM8E4P4 A0ACM8E4P4 LOC115324267 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8042558|UniProtKB=A0ACM8DKX5 A0ACM8DKX5 LOC8042558 PTHR46612:SF1 XYLOSIDE XYLOSYLTRANSFERASE 1 XYLOSIDE XYLOSYLTRANSFERASE 1 glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 transferase#PC00220 IXOSC|EnsemblGenome=LOC8025357|UniProtKB=A0ACM8E7B5 A0ACM8E7B5 LOC8025357 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED IXOSC|EnsemblGenome=LOC8036819|UniProtKB=A0ACM8EKF6 A0ACM8EKF6 LOC8036819 PTHR28641:SF1 FAMILY NOT NAMED MALONYL-COA DECARBOXYLASE, MITOCHONDRIAL IXOSC|EnsemblGenome=LOC115322542|UniProtKB=A0ACM8EGI1 A0ACM8EGI1 LOC115322542 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC121046791|UniProtKB=A0ACM8FTC0 A0ACM8FTC0 LOC121046791 PTHR18966:SF602 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075 synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646 postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC121047602|UniProtKB=A0ACM8FGM5 A0ACM8FGM5 LOC121047602 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121047894|UniProtKB=A0ACM8FH56 A0ACM8FH56 LOC121047894 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121047020|UniProtKB=A0ACM8FE14 A0ACM8FE14 LOC121047020 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115327191|UniProtKB=A0ACM8F112 A0ACM8F112 LOC115327191 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120839492|UniProtKB=A0ACM8EMZ1 A0ACM8EMZ1 LOC120839492 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC115326302|UniProtKB=A0ACM8E6Q7 A0ACM8E6Q7 LOC115326302 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transferase#PC00220 IXOSC|EnsemblGenome=LOC120837463|UniProtKB=A0ACM8EH00 A0ACM8EH00 LOC120837463 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8050985|UniProtKB=A0ACM8DGH9 A0ACM8DGH9 Vps25 PTHR13149:SF0 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN VPS25 VACUOLAR PROTEIN-SORTING-ASSOCIATED PROTEIN 25 modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein localization to organelle#GO:0033365;catabolic process#GO:0009056;protein localization to vacuole#GO:0072665;protein metabolic process#GO:0019538;localization#GO:0051179;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;macromolecule localization#GO:0033036;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;ubiquitin-dependent protein catabolic process#GO:0006511;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043328;late endosome to vacuole transport#GO:0045324;establishment of protein localization to vacuole#GO:0072666;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein transport#GO:0015031;cellular localization#GO:0051641;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192;intracellular protein transport#GO:0006886;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;endosomal transport#GO:0016197 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8027945|UniProtKB=A0ACM8DJF7 A0ACM8DJF7 jdp PTHR44500:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 DNAJ HOMOLOG SUBFAMILY C MEMBER 12 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8052581|UniProtKB=A0ACM8ERR5 A0ACM8ERR5 LOC8052581 PTHR46491:SF3 CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG CDGSH IRON-SULFUR DOMAIN-CONTAINING PROTEIN 3, MITOCHONDRIAL binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 IXOSC|EnsemblGenome=LOC115324822|UniProtKB=A0ACM8E524 A0ACM8E524 LOC115324822 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=ISCI018602|UniProtKB=B7PKZ1 B7PKZ1 IscW_ISCW018602 PTHR46186:SF2 CYSTATIN CYSTATIN-RELATED peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;cysteine-type endopeptidase inhibitor activity#GO:0004869;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;extracellular region#GO:0005576;vesicle#GO:0031982 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115326061|UniProtKB=A0ACM8E5E1 A0ACM8E5E1 Elys PTHR21583:SF8 ELYS PROTEIN PROTEIN ELYS scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121833929|UniProtKB=A0ACM8FNM8 A0ACM8FNM8 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8052057|UniProtKB=A0ACM8EF20 A0ACM8EF20 LOC8052057 PTHR11265:SF0 S-ADENOSYL-METHYLTRANSFERASE MRAW 12S RRNA N(4)-CYTIDINE METHYLTRANSFERASE METTL15 N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;rRNA base methylation#GO:0070475;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA modification#GO:0000154 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8032742|UniProtKB=A0ACM8EAG5 A0ACM8EAG5 LOC8032742 PTHR16255:SF1 REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG REQUIRED FOR MEIOTIC NUCLEAR DIVISION PROTEIN 1 HOMOLOG positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of translation#GO:0045727;positive regulation of protein metabolic process#GO:0051247;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 IXOSC|EnsemblGenome=LOC120836358|UniProtKB=A0ACM8FKG7 A0ACM8FKG7 LOC120836358 PTHR11616:SF328 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873 glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;amino acid transport#GO:0006865;transport#GO:0006810;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115316411|UniProtKB=A0ACM8DWE4 A0ACM8DWE4 LOC115316411 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8036295|UniProtKB=A0ACM8DTW7 A0ACM8DTW7 LOC8036295 PTHR23106:SF25 ANGIOGENIC FACTOR WITH G PATCH AND FHA DOMAINS 1 LD27413P extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120843437|UniProtKB=A0ACM8EX75 A0ACM8EX75 LOC120843437 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029737|UniProtKB=A0ACM8E570 A0ACM8E570 LOC8029737 PTHR45799:SF2 RETICULON-LIKE PROTEIN RETICULON-LIKE PROTEIN organelle organization#GO:0006996;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;endoplasmic reticulum tubular network organization#GO:0071786;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;endoplasmic reticulum membrane organization#GO:0090158;cellular component organization or biogenesis#GO:0071840 neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;axon#GO:0030424;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115311380|UniProtKB=A0ACM8DQN6 A0ACM8DQN6 PTHR28670:SF1 UV-STIMULATED SCAFFOLD PROTEIN A UV-STIMULATED SCAFFOLD PROTEIN A RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515;enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;response to radiation#GO:0009314;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;response to UV#GO:0009411;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8042934|UniProtKB=A0ACM8FBE4 A0ACM8FBE4 LOC8042934 PTHR11616:SF334 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1 solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 import into cell#GO:0098657;establishment of localization#GO:0051234;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;monoatomic cation transport#GO:0006812;localization#GO:0051179;glycine transport#GO:0015816;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8035903|UniProtKB=A0ACM8EIJ6 A0ACM8EIJ6 LOC8035903 PTHR11309:SF152 FRIZZLED PROTEIN SMOOTHENED transmembrane signaling receptor activity#GO:0004888;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515;Wnt-protein binding#GO:0017147 cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;pattern specification process#GO:0007389;system development#GO:0048731;smoothened signaling pathway#GO:0007224;anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;axon development#GO:0061564;axon guidance#GO:0007411;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;axonogenesis#GO:0007409;cellular process#GO:0009987;signal transduction#GO:0007165;neuron projection development#GO:0031175;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dendritic tree#GO:0097447;cilium#GO:0005929;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227 transmembrane signal receptor#PC00197 Hedgehog signaling pathway#P00025>Smoothened#P00685 IXOSC|EnsemblGenome=LOC121046840|UniProtKB=A0ACM8G7U1 A0ACM8G7U1 LOC121046840 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836571|UniProtKB=A0ACM8G048 A0ACM8G048 LOC121836571 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325879|UniProtKB=A0ACM8E566 A0ACM8E566 fzy PTHR19918:SF8 CELL DIVISION CYCLE 20 CDC20 FIZZY -RELATED CELL DIVISION CYCLE PROTEIN 20 HOMOLOG molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047;binding#GO:0005488 metabolic process#GO:0008152;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;macromolecule catabolic process#GO:0009057;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;proteasomal protein catabolic process#GO:0010498;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;positive regulation of protein metabolic process#GO:0051247;modification-dependent macromolecule catabolic process#GO:0043632;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;protein metabolic process#GO:0019538;positive regulation of protein catabolic process#GO:0045732;regulation of protein catabolic process#GO:0042176;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8031066|UniProtKB=A0ACM8F0M4 A0ACM8F0M4 LOC8031066 PTHR24408:SF58 ZINC FINGER PROTEIN LINKING IMMUNITY AND METABOLISM-RELATED DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific DNA binding#GO:0043565 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115316251|UniProtKB=A0ACM8DVT6 A0ACM8DVT6 LOC115316251 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859 glutathione metabolic process#GO:0006749;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 isomerase#PC00135 IXOSC|EnsemblGenome=LOC8043391|UniProtKB=A0ACM8DRT2 A0ACM8DRT2 nac PTHR11132:SF255 SOLUTE CARRIER FAMILY 35 GDP-FUCOSE TRANSPORTER 1 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;organophosphate ester transport#GO:0015748;nucleobase-containing compound transport#GO:0015931;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleotide-sugar transmembrane transport#GO:0015780;nitrogen compound transport#GO:0071705 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8043747|UniProtKB=A0ACM8DGX2 A0ACM8DGX2 LOC8043747 PTHR11309:SF99 FRIZZLED FRIZZLED-4 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;protein binding#GO:0005515;molecular transducer activity#GO:0060089 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;non-canonical Wnt signaling pathway#GO:0035567;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;cell surface receptor signaling pathway#GO:0007166;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475 IXOSC|EnsemblGenome=LOC8052291|UniProtKB=A0ACM8G7D8 A0ACM8G7D8 LOC8052291 PTHR33147:SF39 DEFENSIN-LIKE PROTEIN 1 DEFENSIN-LIKE PROTEIN 98 response to stress#GO:0006950;response to stimulus#GO:0050896;defense response#GO:0006952 antimicrobial response protein#PC00051 IXOSC|EnsemblGenome=LOC120843826|UniProtKB=A0ACM8EWY8 A0ACM8EWY8 LOC120843826 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8030332|UniProtKB=A0ACM8ED48 A0ACM8ED48 ClpX PTHR48102:SF7 ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPX-LIKE, MITOCHONDRIAL-RELATED ATP-DEPENDENT CLPX-LIKE CHAPERONE, MITOCHONDRIAL ATP-dependent activity#GO:0140657;ATP binding#GO:0005524;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 protease#PC00190 IXOSC|EnsemblGenome=LOC120846887|UniProtKB=A0ACM8F4C4 A0ACM8F4C4 LOC120846887 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120841477|UniProtKB=A0ACM8ERT2 A0ACM8ERT2 LOC120841477 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8043777|UniProtKB=A0ACM8DGY6 A0ACM8DGY6 LOC8043777 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120842776|UniProtKB=A0ACM8EVN3 A0ACM8EVN3 LOC120842776 PTHR39299:SF1 TRANSMEMBRANE PROTEIN DUF7789 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320718|UniProtKB=A0ACM8E0D6 A0ACM8E0D6 LOC115320718 PTHR45937:SF1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN 1 ASPARAGINE SYNTHETASE DOMAIN-CONTAINING PROTEIN CG17486 IXOSC|EnsemblGenome=LOC8051168|UniProtKB=A0ACM8FEI9 A0ACM8FEI9 LOC8051168 PTHR46231:SF1 ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1 ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC8025554|UniProtKB=A0ACM8DW83 A0ACM8DW83 LOC8025554 PTHR21595:SF0 PATRONIN PATRONIN protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 cytoplasmic microtubule organization#GO:0031122;regulation of cellular process#GO:0050794;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cellular component organization#GO:0016043;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of biological process#GO:0048519;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex disassembly#GO:0043242;microtubule cytoskeleton organization#GO:0000226;negative regulation of cytoskeleton organization#GO:0051494;regulation of microtubule-based process#GO:0032886;negative regulation of protein depolymerization#GO:1901880;regulation of microtubule cytoskeleton organization#GO:0070507;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;microtubule end#GO:1990752;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 IXOSC|EnsemblGenome=LOC8024884|UniProtKB=A0ACM8DIR9 A0ACM8DIR9 LOC8024884 PTHR16852:SF2 GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN GTP CYCLOHYDROLASE 1 FEEDBACK REGULATORY PROTEIN enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC121046809|UniProtKB=A0ACM8FF21 A0ACM8FF21 LOC121046809 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8050901|UniProtKB=A0ACM8DLQ4 A0ACM8DLQ4 LOC8050901 PTHR11820:SF7 ACYLPYRUVASE OXALOACETATE TAUTOMERASE FAHD1, MITOCHONDRIAL catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120836234|UniProtKB=A0ACM8FB32 A0ACM8FB32 LOC120836234 PTHR24253:SF153 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121835420|UniProtKB=A0ACM8FUK6 A0ACM8FUK6 LOC121835420 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115332816|UniProtKB=A0ACM8EE00 A0ACM8EE00 LOC115332816 PTHR13234:SF82 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE-LIKE PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8026328|UniProtKB=A0ACM8DMR5 A0ACM8DMR5 LOC8026328 PTHR12125:SF5 F-BOX ONLY PROTEIN 6-LIKE PROTEIN F-BOX DOMAIN-CONTAINING PROTEIN ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121837652|UniProtKB=A0ACM8G5E9 A0ACM8G5E9 LOC121837652 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309195|UniProtKB=A0ACM8EY78 A0ACM8EY78 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120837655|UniProtKB=A0ACM8FXH1 A0ACM8FXH1 LOC120837655 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115308181|UniProtKB=A0ACM8F7E7 A0ACM8F7E7 LOC115308181 PTHR12369:SF11 CHONDROITIN SYNTHASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan metabolic process#GO:0050654;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;glycoprotein biosynthetic process#GO:0009101;proteoglycan metabolic process#GO:0006029;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC121837416|UniProtKB=A0ACM8G4J6 A0ACM8G4J6 LOC121837416 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033494|UniProtKB=A0ACM8EG96 A0ACM8EG96 wuho PTHR16288:SF0 WD40 REPEAT PROTEIN 4 TRNA (GUANINE-N(7)-)-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT WDR4 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8042515|UniProtKB=A0ACM8DWP0 A0ACM8DWP0 LOC8042515 PTHR12191:SF37 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER ZIP8 monoatomic cation transmembrane transporter activity#GO:0008324;transition metal ion transmembrane transporter activity#GO:0046915;symporter activity#GO:0015293;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;bicarbonate transmembrane transporter activity#GO:0015106;zinc ion transmembrane transporter activity#GO:0005385;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;import into cell#GO:0098657;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8035350|UniProtKB=A0ACM8ETJ5 A0ACM8ETJ5 LOC8035350 PTHR33236:SF13 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039744|UniProtKB=A0ACM8DXG3 A0ACM8DXG3 LOC120848102 PTHR12050:SF0 LEPTIN RECEPTOR-RELATED RH04491P retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120843397|UniProtKB=A0ACM8EW31 A0ACM8EW31 LOC120843397 PTHR33198:SF22 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046226|UniProtKB=A0ACM8FDF4 A0ACM8FDF4 LOC121046226 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8033273|UniProtKB=A0ACM8FC75 A0ACM8FC75 LOC8033273 PTHR18861:SF5 ELKS/RAB6-INTERACTING/CAST PROTEIN PROTEIN BRUCHPILOT structural molecule activity#GO:0005198;structural constituent of synapse#GO:0098918 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 cytoplasm#GO:0005737;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938;presynapse#GO:0098793;intracellular anatomical structure#GO:0005622;presynaptic active zone#GO:0048786;cell junction#GO:0030054 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121834090|UniProtKB=A0ACM8FPE3 A0ACM8FPE3 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8024599|UniProtKB=A0ACM8E1A3 A0ACM8E1A3 ras PTHR11911:SF111 INOSINE-5-MONOPHOSPHATE DEHYDROGENASE RELATED INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 ribose phosphate biosynthetic process#GO:0046390;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407 dehydrogenase#PC00092 De novo purine biosynthesis#P02738>IMP dehydrogenase#P02895 IXOSC|EnsemblGenome=LOC8029268|UniProtKB=A0ACM8FRU6 A0ACM8FRU6 LOC8029268 PTHR11412:SF171 MACROGLOBULIN / COMPLEMENT ALPHA-2-MACROGLOBULIN-LIKE ISOFORM X1 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121046313|UniProtKB=A0ACM8EFE5 A0ACM8EFE5 LOC121046313 PTHR18806:SF4 RBM25 PROTEIN RNA-BINDING PROTEIN 25 nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468 IXOSC|EnsemblGenome=LOC8028987|UniProtKB=A0ACM8DPH4 A0ACM8DPH4 LOC8028987 PTHR20849:SF2 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN MEXTLI EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN MEXTLI translation factor activity#GO:0180051;binding#GO:0005488;translation initiation factor activity#GO:0003743;protein binding#GO:0005515;translation initiation factor binding#GO:0031369 regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;positive regulation of translation#GO:0045727;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608 cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8043254|UniProtKB=A0ACM8E9F3 A0ACM8E9F3 LOC8043254 PTHR12202:SF0 ESF1 HOMOLOG ESF1 HOMOLOG binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 IXOSC|EnsemblGenome=LOC8042981|UniProtKB=A0ACM8FCV3 A0ACM8FCV3 PTHR11879:SF55 ASPARTATE AMINOTRANSFERASE ASPARTATE AMINOTRANSFERASE, CYTOPLASMIC small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transaminase#PC00216;transferase#PC00220 Asparagine and aspartate biosynthesis#P02730>Aspartate aminotransferase#P02854 IXOSC|EnsemblGenome=LOC121833956|UniProtKB=A0ACM8FNR1 A0ACM8FNR1 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8037153|UniProtKB=A0ACM8E0U8 A0ACM8E0U8 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ribonucleoside triphosphate phosphatase activity#GO:0017111;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC115333144|UniProtKB=A0ACM8EEI0 A0ACM8EEI0 LOC115333144 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120850193|UniProtKB=A0ACM8F9B6 A0ACM8F9B6 LOC120850193 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8030718|UniProtKB=A0ACM8FMB5 A0ACM8FMB5 LOC8030718 PTHR12612:SF48 NUCLEAR TRANSPORT FACTOR 2 NUCLEAR TRANSPORT FACTOR 2 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8025632|UniProtKB=A0ACM8FBK6 A0ACM8FBK6 LOC8025632 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120848221|UniProtKB=A0ACM8F4K3 A0ACM8F4K3 LOC120848221 PTHR36943:SF2 CCHC-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332711|UniProtKB=A0ACM8EDU8 A0ACM8EDU8 LOC115332711 PTHR31633:SF1 H/ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 H_ACA RIBONUCLEOPROTEIN COMPLEX NON-CORE SUBUNIT NAF1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization or biogenesis#GO:0071840;protein-RNA complex assembly#GO:0022618;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;ribosome biogenesis#GO:0042254;cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987 sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 IXOSC|EnsemblGenome=LOC121837060|UniProtKB=A0ACM8G1H6 A0ACM8G1H6 LOC121837060 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115329766|UniProtKB=A0ACM8EA05 A0ACM8EA05 LOC115329766 PTHR22984:SF33 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8034219|UniProtKB=A0ACM8E3G4 A0ACM8E3G4 Ufsp2 PTHR48153:SF6 UFM1-SPECIFIC PROTEASE 2 UFM1-SPECIFIC PROTEASE 2 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121837321|UniProtKB=A0ACM8G371 A0ACM8G371 LOC121837321 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8039808|UniProtKB=A0ACM8EGM5 A0ACM8EGM5 LOC8039808 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;organelle organization#GO:0006996;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC8052027|UniProtKB=A0ACM8ECD0 A0ACM8ECD0 Sbf PTHR10807:SF109 MYOTUBULARIN-RELATED SET DOMAIN BINDING FACTOR, ISOFORM A hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 phospholipid metabolic process#GO:0006644;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid dephosphorylation#GO:0046839;cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;dephosphorylation#GO:0016311;lipid modification#GO:0030258;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;phosphatidylinositol dephosphorylation#GO:0046856 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC120850115|UniProtKB=A0ACM8FUT8 A0ACM8FUT8 LOC120850115 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8028862|UniProtKB=A0ACM8DHB9 A0ACM8DHB9 LOC8028862 PTHR11588:SF501 TUBULIN TUBULIN ALPHA CHAIN small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 microtubule#GO:0005874;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;tubulin#PC00228 IXOSC|EnsemblGenome=LOC120849285|UniProtKB=A0ACM8F7U7 A0ACM8F7U7 LOC120849285 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8043923|UniProtKB=A0ACM8EVZ3 A0ACM8EVZ3 LOC8043923 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8028294|UniProtKB=A0ACM8E4A0 A0ACM8E4A0 LOC8028294 PTHR22775:SF51 SORTING NEXIN SORTING NEXIN-13 anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>RGS-PX1#P00706 IXOSC|EnsemblGenome=LOC8053684|UniProtKB=A0ACM8F7Q2 A0ACM8F7Q2 LOC8053684 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115331155|UniProtKB=A0ACM8FMK7 A0ACM8FMK7 LOC115331155 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115313181|UniProtKB=A0ACM8DSI5 A0ACM8DSI5 LOC115313181 PTHR21092:SF1 NICASTRIN NICASTRIN primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 Alzheimer disease-presenilin pathway#P00004>Nicastrin#P00115;Notch signaling pathway#P00045>Nicastrin#P01108;Alzheimer disease-amyloid secretase pathway#P00003>Nicastrin#P00095 IXOSC|EnsemblGenome=LOC8029110|UniProtKB=A0ACM8FAJ1 A0ACM8FAJ1 LOC8029110 PTHR15711:SF22 RAP GTPASE-ACTIVATING PROTEIN RAP GTPASE ACTIVATING PROTEIN 1, ISOFORM H GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC120839636|UniProtKB=A0ACM8EMS1 A0ACM8EMS1 LOC120839636 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120846920|UniProtKB=A0ACM8F3A9 A0ACM8F3A9 LOC120846920 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040984|UniProtKB=A0ACM8DGS0 A0ACM8DGS0 Nup160 PTHR21286:SF0 NUCLEAR PORE COMPLEX PROTEIN NUP160 NUCLEAR PORE COMPLEX PROTEIN NUP160 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;gene expression#GO:0010467;response to chemical#GO:0042221;chromosome localization#GO:0050000;response to temperature stimulus#GO:0009266;protein export from nucleus#GO:0006611;response to stress#GO:0006950;organelle organization#GO:0006996;response to heat#GO:0009408;cellular component biogenesis#GO:0044085;cellular response to heat#GO:0034605;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein transport#GO:0015031;protein import into nucleus#GO:0006606;ribosome biogenesis#GO:0042254;telomere tethering at nuclear periphery#GO:0034398;cellular response to stress#GO:0033554;establishment of organelle localization#GO:0051656;response to stimulus#GO:0050896;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;response to abiotic stimulus#GO:0009628;ribosomal large subunit export from nucleus#GO:0000055;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;chromosome organization#GO:0051276;intracellular protein localization#GO:0008104;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000973;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;response to nitrogen compound#GO:1901698;organelle localization#GO:0051640;nucleocytoplasmic transport#GO:0006913;ribosome localization#GO:0033750;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;telomere localization#GO:0034397;cellular response to stimulus#GO:0051716 nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;organelle envelope#GO:0031967 transporter#PC00227 IXOSC|EnsemblGenome=LOC8034148|UniProtKB=A0ACM8EEL8 A0ACM8EEL8 LOC8034148 PTHR13617:SF14 PROTEIN ABHD18 CARDIOLIPIN-SPECIFIC DEACYLASE, MITOCHONDRIAL phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;lipase activity#GO:0016298;hydrolase activity#GO:0016787 glycerophospholipid metabolic process#GO:0006650;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 IXOSC|EnsemblGenome=LOC121838515|UniProtKB=A0ACM8G8J2 A0ACM8G8J2 LOC121838515 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120838167|UniProtKB=A0ACM8EJZ3 A0ACM8EJZ3 LOC120838167 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836527|UniProtKB=A0ACM8FZY4 A0ACM8FZY4 LOC121836527 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC120839661|UniProtKB=A0ACM8EMH8 A0ACM8EMH8 LOC120839661 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121834680|UniProtKB=A0ACM8FPH1 A0ACM8FPH1 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316934|UniProtKB=A0ACM8FXL5 A0ACM8FXL5 CSN7 PTHR15350:SF5 COP9 SIGNALOSOME COMPLEX SUBUNIT 7/DENDRITIC CELL PROTEIN GA17 COP9 SIGNALOSOME COMPLEX SUBUNIT 7 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115313153|UniProtKB=A0ACM8DSH1 A0ACM8DSH1 LOC115313153 PTHR46560:SF16 CYPHER, ISOFORM B ZP DOMAIN-CONTAINING PROTEIN anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;cell morphogenesis#GO:0000902;anatomical structure development#GO:0048856 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC115309982|UniProtKB=A0ACM8EI35 A0ACM8EI35 LOC115309982 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120837764|UniProtKB=A0ACM8EIY4 A0ACM8EIY4 slim PTHR46428:SF1 KELCH DOMAIN-CONTAINING PROTEIN 10 KELCH DOMAIN-CONTAINING PROTEIN 10 regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135;positive regulation of signaling#GO:0023056;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stress#GO:0080134;positive regulation of MAPK cascade#GO:0043410 IXOSC|EnsemblGenome=LOC115333005|UniProtKB=A0ACM8EF84 A0ACM8EF84 LOC115333005 PTHR10188:SF8 L-ASPARAGINASE THREONINE ASPARTASE 1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8024791|UniProtKB=A0ACM8EF85 A0ACM8EF85 LOC8024791 PTHR12264:SF21 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 12 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 general transcription factor#PC00259;RNA metabolism protein#PC00031 General transcription regulation#P00023>TBP-associated factors#P00658;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385 IXOSC|EnsemblGenome=LOC8023233|UniProtKB=A0ACM8G5G5 A0ACM8G5G5 LOC8023233 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869;transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876 intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120842902|UniProtKB=A0ACM8EUR2 A0ACM8EUR2 LOC120842902 PTHR47501:SF5 TRANSPOSASE-RELATED BED-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8042869|UniProtKB=A0ACM8FU08 A0ACM8FU08 LOC8042869 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8037168|UniProtKB=A0ACM8ETI0 A0ACM8ETI0 LOC8037168 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8038667|UniProtKB=A0ACM8ED72 A0ACM8ED72 PTHR11119:SF3 XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER LD30822P transporter#PC00227 IXOSC|EnsemblGenome=LOC120841192|UniProtKB=A0ACM8ER71 A0ACM8ER71 LOC120841192 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8029517|UniProtKB=A0ACM8DYI1 A0ACM8DYI1 LOC8029517 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC115316804|UniProtKB=A0ACM8DX20 A0ACM8DX20 LOC115316804 PTHR10404:SF84 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG catalytic activity#GO:0003824;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8027491|UniProtKB=A0ACM8F502 A0ACM8F502 LOC8027491 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121834153|UniProtKB=A0ACM8FPJ5 A0ACM8FPJ5 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8033259|UniProtKB=A0ACM8FMX7 A0ACM8FMX7 PTHR10336:SF6 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE EPSILON-1 lipase activity#GO:0016298;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;organophosphate metabolic process#GO:0019637;monoatomic ion transmembrane transport#GO:0034220;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;signaling#GO:0023052;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;G protein-coupled receptor signaling pathway#GO:0007186;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;monoatomic cation transmembrane transport#GO:0098655;glycerophospholipid metabolic process#GO:0006650;metabolic process#GO:0008152;calcium ion transport#GO:0006816;calcium ion transmembrane import into cytosol#GO:0097553 hydrolase#PC00121;phospholipase#PC00186;metabolite interconversion enzyme#PC00262;lipase#PC00143 Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Alpha adrenergic receptor signaling pathway#P00002>PLC#P00073;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 IXOSC|EnsemblGenome=LOC8031639|UniProtKB=A0ACM8FK45 A0ACM8FK45 PGS1 PTHR12586:SF1 CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE, MITOCHONDRIAL transferase#PC00220 IXOSC|EnsemblGenome=LOC120841133|UniProtKB=A0ACM8ER04 A0ACM8ER04 LOC120841133 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115325433|UniProtKB=A0ACM8FIG5 A0ACM8FIG5 LOC115325433 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115326947|UniProtKB=A0ACM8G4G1 A0ACM8G4G1 LOC115326947 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046096|UniProtKB=A0ACM8FWH9 A0ACM8FWH9 LOC121046096 PTHR11733:SF242 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED SUBFAMILY NOT NAMED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120844131|UniProtKB=A0ACM8EY04 A0ACM8EY04 LOC120844131 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8052312|UniProtKB=A0ACM8EBH9 A0ACM8EBH9 LOC8052312 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213 oxidoreductase complex#GO:1990204;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8050745|UniProtKB=A0ACM8DLW0 A0ACM8DLW0 LOC8050745 PTHR18884:SF69 SEPTIN SEPTIN-RELATED hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817 intracellular protein localization#GO:0008104;cytoskeleton-dependent cytokinesis#GO:0061640;localization#GO:0051179;cytokinesis#GO:0000910;cellular process#GO:0009987;cell cycle process#GO:0022402;cell division#GO:0051301;macromolecule localization#GO:0033036;cell cycle#GO:0007049 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8041039|UniProtKB=A0ACM8E221 A0ACM8E221 LOC8041039 PTHR11440:SF114 LECITHIN-CHOLESTEROL ACYLTRANSFERASE-RELATED BCDNA.GH02384 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120848986|UniProtKB=A0ACM8F6P9 A0ACM8F6P9 LOC120848986 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318989|UniProtKB=A0ACM8DZ76 A0ACM8DZ76 LOC115318989 PTHR10545:SF29 DIAMINE N-ACETYLTRANSFERASE GH14572P-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740 acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC121046700|UniProtKB=A0ACM8FFM4 A0ACM8FFM4 LOC121046700 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309684|UniProtKB=A0ACM8DP25 A0ACM8DP25 LOC115309684 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC121835917|UniProtKB=A0ACM8FXG8 A0ACM8FXG8 LOC121835917 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;post-embryonic development#GO:0009791;cell adhesion#GO:0007155;developmental process#GO:0032502;circulatory system development#GO:0072359;heart development#GO:0007507;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115319829|UniProtKB=A0ACM8F9Y8 A0ACM8F9Y8 LOC115319829 PTHR24381:SF393 ZINC FINGER PROTEIN LD39664P-RELATED DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8041362|UniProtKB=A0ACM8FHT8 A0ACM8FHT8 LOC8041362 PTHR24256:SF579 TRYPTASE-RELATED WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115326824|UniProtKB=A0ACM8F6Y0 A0ACM8F6Y0 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030744|UniProtKB=A0ACM8G2Z1 A0ACM8G2Z1 LOC8030744 PTHR11848:SF314 TGF-BETA FAMILY TGF-BETA FAMILY PROFILE DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 IXOSC|EnsemblGenome=LOC8038486|UniProtKB=A0ACM8DK61 A0ACM8DK61 LOC8038486 PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT B, MITOCHONDRIAL monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;organophosphate biosynthetic process#GO:0090407;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206 transporter complex#GO:1990351;organelle membrane#GO:0031090;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739 primary active transporter#PC00068;ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC8034263|UniProtKB=A0ACM8DT30 A0ACM8DT30 LOC8034263 PTHR24067:SF371 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 T cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121835894|UniProtKB=A0ACM8FX23 A0ACM8FX23 LOC121835894 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330000|UniProtKB=A0ACM8FHQ4 A0ACM8FHQ4 LOC115330000 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115318136|UniProtKB=A0ACM8EII1 A0ACM8EII1 LOC115318136 PTHR23080:SF63 THAP DOMAIN PROTEIN DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043712|UniProtKB=A0ACM8DS21 A0ACM8DS21 PTHR12400:SF110 INOSITOL POLYPHOSPHATE KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 kinase#PC00137 IXOSC|EnsemblGenome=LOC8033651|UniProtKB=A0ACM8F876 A0ACM8F876 LOC8033651 PTHR13843:SF12 MICROTUBULE-ASSOCIATED PROTEIN MICROTUBULE-ASSOCIATED PROTEIN FUTSCH protein binding#GO:0005515;microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;tubulin binding#GO:0015631 axon development#GO:0061564;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of protein depolymerization#GO:1901879;regulation of microtubule polymerization or depolymerization#GO:0031110;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of supramolecular fiber organization#GO:1902903;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of microtubule-based process#GO:0032886;system development#GO:0048731;microtubule cytoskeleton organization#GO:0000226;anatomical structure development#GO:0048856;cellular process#GO:0009987;organelle organization#GO:0006996;neuron projection development#GO:0031175;regulation of protein-containing complex disassembly#GO:0043244;cytoskeleton organization#GO:0007010;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;regulation of microtubule cytoskeleton organization#GO:0070507;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component organization#GO:0051128;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;neuron development#GO:0048666;dendrite development#GO:0016358 cell body#GO:0044297;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;dendrite#GO:0030425;dendritic tree#GO:0097447;intracellular organelle#GO:0043229;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytosol#GO:0005829;microtubule cytoskeleton#GO:0015630;neuron projection#GO:0043005;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cell junction#GO:0030054 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC121836597|UniProtKB=A0ACM8FZC5 A0ACM8FZC5 LOC121836597 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular process#GO:0009987;system development#GO:0048731;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;developmental process#GO:0032502;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;animal gross anatomical part developmental process#GO:0160108 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121834798|UniProtKB=A0ACM8FQZ7 A0ACM8FQZ7 LOC121834798 PTHR23043:SF39 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA DYSFUSION, ISOFORM D sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8052061|UniProtKB=A0ACM8E9F6 A0ACM8E9F6 LOC8052061 PTHR24104:SF47 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED THIN, ISOFORM C transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121833861|UniProtKB=A0ACM8FNK8 A0ACM8FNK8 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314377|UniProtKB=A0ACM8EIZ7 A0ACM8EIZ7 LOC115314377 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8025809|UniProtKB=A0ACM8DGF9 A0ACM8DGF9 LOC8025809 PTHR22602:SF0 IRON-SULFUR CLUSTER ASSEMBLY FACTOR CAF17/IBA57, MITOCHONDRIAL IRON-SULFUR CLUSTER ASSEMBLY FACTOR IBA57, MITOCHONDRIAL membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC115309907|UniProtKB=A0ACM8ETU4 A0ACM8ETU4 LOC115309907 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120837355|UniProtKB=A0ACM8EH82 A0ACM8EH82 LOC120837355 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8052254|UniProtKB=A0ACM8DM43 A0ACM8DM43 LOC8052254 PTHR15379:SF2 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 CELL GROWTH REGULATOR WITH RING FINGER DOMAIN PROTEIN 1 regulation of cellular process#GO:0050794;regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;negative regulation of cell growth#GO:0030308;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of growth#GO:0040008;negative regulation of cellular process#GO:0048523 IXOSC|EnsemblGenome=LOC120847968|UniProtKB=A0ACM8F4Y3 A0ACM8F4Y3 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325441|UniProtKB=A0ACM8E674 A0ACM8E674 LOC115325441 PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity#GO:0016787;phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on ester bonds#GO:0016788;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;phosphoric ester hydrolase activity#GO:0042578 regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;RNA decapping#GO:0110154;RNA catabolic process#GO:0006401;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115314933|UniProtKB=A0ACM8ESJ7 A0ACM8ESJ7 LOC115314933 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8028023|UniProtKB=A0ACM8DSK2 A0ACM8DSK2 LOC8028023 PTHR23235:SF188 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC-FINGER TRANSCRIPTION FACTOR RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8027549|UniProtKB=A0ACM8EY87 A0ACM8EY87 LOC8027549 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8044113|UniProtKB=A0ACM8DRG9 A0ACM8DRG9 nompC PTHR24121:SF35 NO MECHANORECEPTOR POTENTIAL C, ISOFORM D-RELATED NO MECHANORECEPTOR POTENTIAL C, ISOFORM H system process#GO:0003008;sensory perception of sound#GO:0007605;multicellular organismal process#GO:0032501;sensory perception of mechanical stimulus#GO:0050954;sensory perception#GO:0007600;nervous system process#GO:0050877 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120839956|UniProtKB=A0ACM8EP19 A0ACM8EP19 LOC120839956 PTHR24252:SF41 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11D-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8026704|UniProtKB=A0ACM8E488 A0ACM8E488 LOC8026704 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120851158|UniProtKB=A0ACM8FBK0 A0ACM8FBK0 LOC8043790 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8036469|UniProtKB=A0ACM8DJW8 A0ACM8DJW8 alien PTHR10678:SF3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 COP9 SIGNALOSOME COMPLEX SUBUNIT 2 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;post-translational protein modification#GO:0043687 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8039599|UniProtKB=A0ACM8EAM2 A0ACM8EAM2 PTHR31532:SF10 BIORIENTATION OF CHROMOSOMES IN CELL DIVISION 1 FAMILY MEMBER BIORIENTATION OF CHROMOSOMES IN CELL DIVISION PROTEIN 1-LIKE 1 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139 nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC8031260|UniProtKB=A0ACM8ED42 A0ACM8ED42 LOC8031260 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120844145|UniProtKB=A0ACM8EY08 A0ACM8EY08 LOC120844145 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037522|UniProtKB=A0ACM8EW51 A0ACM8EW51 Pkn PTHR24356:SF210 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE N protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 non-receptor serine/threonine protein kinase#PC00167 Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074 IXOSC|EnsemblGenome=LOC115328102|UniProtKB=A0ACM8EUG3 A0ACM8EUG3 LOC115328102 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC115317410|UniProtKB=A0ACM8FBI5 A0ACM8FBI5 LOC115317410 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115326206|UniProtKB=A0ACM8FLV2 A0ACM8FLV2 LOC115326206 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239;catalytic activity#GO:0003824 negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;RNA metabolic process#GO:0016070;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of protein metabolic process#GO:0051248;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 cytosol#GO:0005829;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121;deaminase#PC00088;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8029944|UniProtKB=A0ACM8E0F0 A0ACM8E0F0 LOC8029944 PTHR19211:SF117 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;ATP binding#GO:0005524;binding#GO:0005488;anion binding#GO:0043168;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC8043695|UniProtKB=A0ACM8E6U8 A0ACM8E6U8 LOC8043695 PTHR11932:SF76 CULLIN CULLIN-5 protein complex scaffold activity#GO:0140378;enzyme binding#GO:0019899;ubiquitin-like protein ligase binding#GO:0044389;binding#GO:0005488;structural molecule activity#GO:0005198;ubiquitin protein ligase binding#GO:0031625;protein binding#GO:0005515 protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;Cul5-RING ubiquitin ligase complex#GO:0031466;ubiquitin ligase complex#GO:0000151;nucleus#GO:0005634;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8023152|UniProtKB=A0ACM8E7S6 A0ACM8E7S6 drk PTHR46037:SF1 PROTEIN ENHANCER OF SEVENLESS 2B GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 signaling receptor binding#GO:0005102;binding#GO:0005488;growth factor receptor binding#GO:0070851;protein binding#GO:0005515 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of MAPK cascade#GO:0043408 nuclear protein-containing complex#GO:0140513;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cell periphery#GO:0071944;nucleus#GO:0005634;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;COP9 signalosome#GO:0008180;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 FGF signaling pathway#P00021>Grb2#P00631;PI3 kinase pathway#P00048>Grb2#P01178;Angiogenesis#P00005>Grb2#P00234;Angiogenesis#P00005>Grb2#P00252;EGF receptor signaling pathway#P00018>Grb2#P00550;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>Grb2#P00892;PDGF signaling pathway#P00047>Grb2#P01148 IXOSC|EnsemblGenome=LOC8023806|UniProtKB=A0ACM8DHK8 A0ACM8DHK8 Cnep1r2 PTHR20996:SF1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 NUCLEAR ENVELOPE PHOSPHATASE-REGULATORY SUBUNIT 1 nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;membrane protein complex#GO:0098796;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC8039806|UniProtKB=A0ACM8EH55 A0ACM8EH55 LOC8039806 PTHR20973:SF0 NON-SMC ELEMENT 1-RELATED NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 1 HOMOLOG acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 chromosome#GO:0005694;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;condensed chromosome#GO:0000793;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120841685|UniProtKB=A0ACM8ESA4 A0ACM8ESA4 LOC120841685 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179;amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115309268|UniProtKB=A0ACM8DNG8 A0ACM8DNG8 LOC115309268 PTHR37162:SF11 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115316621|UniProtKB=A0ACM8FTN8 A0ACM8FTN8 LOC115316621 PTHR43788:SF20 DNA2/NAM7 HELICASE FAMILY MEMBER DNA-BINDING PROTEIN SMUBP-2 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stress#GO:0006950;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8034515|UniProtKB=A0ACM8FJN7 A0ACM8FJN7 LOC8034515 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115315064|UniProtKB=A0ACM8DUY6 A0ACM8DUY6 LOC115315064 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8050949|UniProtKB=A0ACM8DYE7 A0ACM8DYE7 LOC8050949 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC8044139|UniProtKB=A0ACM8EJ65 A0ACM8EJ65 LOC8044139 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;enzyme regulator activity#GO:0030234;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824 positive regulation of biological process#GO:0048518;negative regulation of programmed cell death#GO:0043069;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;positive regulation of protein ubiquitination#GO:0031398;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;regulation of protein modification process#GO:0031399;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of cell cycle#GO:0051726;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120850504|UniProtKB=A0ACM8F8W7 A0ACM8F8W7 LOC120850504 PTHR43725:SF58 UDP-GLUCOSE 4-EPIMERASE UDP-GLUCOSE 4-EPIMERASE racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;isomerase activity#GO:0016853 carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;phosphorus metabolic process#GO:0006793;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 epimerase/racemase#PC00096 Fructose galactose metabolism#P02744>UDP Glucose 4 epimerase#P02965 IXOSC|EnsemblGenome=LOC120844092|UniProtKB=A0ACM8EXH9 A0ACM8EXH9 LOC120844092 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8036625|UniProtKB=A0ACM8DUY4 A0ACM8DUY4 Rim2 PTHR45829:SF4 MITOCHONDRIAL CARRIER PROTEIN RIM2 MITOCHONDRIAL CARRIER PROTEIN RIM2 nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 secondary carrier transporter#PC00258;mitochondrial carrier protein#PC00158 IXOSC|EnsemblGenome=LOC8024033|UniProtKB=A0ACM8EID6 A0ACM8EID6 LOC8024033 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120846192|UniProtKB=A0ACM8F113 A0ACM8F113 LOC120846192 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115313880|UniProtKB=A0ACM8EN98 A0ACM8EN98 LOC115313880 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8027400|UniProtKB=A0ACM8E3S8 A0ACM8E3S8 LOC8027400 PTHR12300:SF197 HVA22-LIKE PROTEINS LP05237P-RELATED cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;microtubule binding#GO:0008017;binding#GO:0005488;protein binding#GO:0005515 endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum tubular network organization#GO:0071786 cytoplasmic microtubule#GO:0005881;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;supramolecular fiber#GO:0099512;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;endoplasmic reticulum tubular network#GO:0071782;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;endoplasmic reticulum#GO:0005783;cytoskeleton#GO:0005856;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120842270|UniProtKB=A0ACM8G321 A0ACM8G321 LOC120842270 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326776|UniProtKB=A0ACM8E7T9 A0ACM8E7T9 LOC115326776 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837493|UniProtKB=A0ACM8EHH8 A0ACM8EHH8 LOC120837493 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8043396|UniProtKB=A0ACM8DTB4 A0ACM8DTB4 LOC8043396 PTHR12317:SF0 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 primary metabolic process#GO:0044238;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;neutral lipid metabolic process#GO:0006638 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120846286|UniProtKB=A0ACM8F1Y1 A0ACM8F1Y1 LOC120846286 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8024207|UniProtKB=A0ACM8DI06 A0ACM8DI06 LOC8024207 PTHR16193:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 27 TETRATRICOPEPTIDE REPEAT PROTEIN 27 IXOSC|EnsemblGenome=LOC8026218|UniProtKB=A0ACM8FRN8 A0ACM8FRN8 LOC8026218 PTHR11036:SF90 SEMAPHORIN SEMAPHORIN-2A molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 system development#GO:0048731;anatomical structure development#GO:0048856;regulation of cell motility#GO:2000145;cell communication#GO:0007154;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;cellular developmental process#GO:0048869;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;regulation of cell migration#GO:0030334;regulation of locomotion#GO:0040012;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522;axon guidance#GO:0007411;axon development#GO:0061564;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;signaling#GO:0023052;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;response to chemical#GO:0042221;taxis#GO:0042330;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;neuron projection development#GO:0031175 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 IXOSC|EnsemblGenome=LOC8040011|UniProtKB=A0ACM8DUQ3 A0ACM8DUQ3 LOC8040011 PTHR45639:SF3 HSC70CB, ISOFORM G-RELATED HYPOXIA UP-REGULATED PROTEIN 1 nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622 chaperone#PC00072;Hsp70 family chaperone#PC00027 IXOSC|EnsemblGenome=LOC8041810|UniProtKB=A0ACM8DTS1 A0ACM8DTS1 LOC8041810 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833111|UniProtKB=A0ACM8FJA3 A0ACM8FJA3 LOC121833111 PTHR24416:SF655 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8036701|UniProtKB=A0ACM8FBK9 A0ACM8FBK9 PTHR15608:SF0 SPLICING FACTOR U2AF-ASSOCIATED PROTEIN 2 17S U2 SNRNP COMPLEX COMPONENT HTATSF1 nucleic acid binding#GO:0003676;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;RNA binding#GO:0003723;chromatin-protein adaptor activity#GO:0140463 macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;localization#GO:0051179;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;protein localization to organelle#GO:0033365;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003 nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membraneless organelle#GO:0043228;U2 snRNP#GO:0005686;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;small nuclear ribonucleoprotein complex#GO:0030532;site of double-strand break#GO:0035861;nucleus#GO:0005634;spliceosomal snRNP complex#GO:0097525;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;chromosome#GO:0005694 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8025182|UniProtKB=A0ACM8F2M5 A0ACM8F2M5 LOC8025182 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115327842|UniProtKB=A0ACM8FUS2 A0ACM8FUS2 LOC115327842 PTHR10117:SF80 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT-RECEPTOR-POTENTIAL-LIKE PROTEIN channel activity#GO:0015267;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;binding#GO:0005488;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;alcohol binding#GO:0043178;transporter activity#GO:0005215 monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;single fertilization#GO:0007338;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;metal ion transport#GO:0030001;homeostatic process#GO:0042592;reproductive process#GO:0022414;fertilization#GO:0009566;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;regulation of cytosolic calcium ion concentration#GO:0051480;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;sexual reproduction#GO:0019953;inorganic ion homeostasis#GO:0098771 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ion channel#PC00133 IXOSC|EnsemblGenome=LOC120844426|UniProtKB=A0ACM8EYQ0 A0ACM8EYQ0 LOC120844426 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120837135|UniProtKB=A0ACM8EGQ2 A0ACM8EGQ2 LOC8024196 PTHR13501:SF10 CHLOROPLAST 50S RIBOSOMAL PROTEIN L22-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL22M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115317557|UniProtKB=A0ACM8EZS9 A0ACM8EZS9 LOC115317557 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839486|UniProtKB=A0ACM8EL97 A0ACM8EL97 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120842942|UniProtKB=A0ACM8EW35 A0ACM8EW35 LOC120842942 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8038917|UniProtKB=A0ACM8DK68 A0ACM8DK68 LOC8038917 PTHR21174:SF0 FAMILY NOT NAMED HD PHOSPHOHYDROLASE FAMILY PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120838991|UniProtKB=A0ACM8EL08 A0ACM8EL08 LOC120838991 PTHR16295:SF10 TRAF-TYPE ZINC FINGER PROTEIN-RELATED EXPRESSED PROTEIN intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115314691|UniProtKB=A0ACM8FWS6 A0ACM8FWS6 LOC115314691 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8042507|UniProtKB=A0ACM8E036 A0ACM8E036 LOC8042507 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120846609|UniProtKB=A0ACM8F2R4 A0ACM8F2R4 LOC120846609 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;small molecule catabolic process#GO:0044282;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120849293|UniProtKB=A0ACM8F6K9 A0ACM8F6K9 Nmnat PTHR12039:SF0 NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE NICOTINAMIDE-NUCLEOTIDE ADENYLYLTRANSFERASE nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;pyridine-containing compound metabolic process#GO:0072524;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 transferase#PC00220;nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC120846892|UniProtKB=A0ACM8FYQ1 A0ACM8FYQ1 LOC120846892 PTHR45712:SF22 AGAP008170-PA LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 4 IXOSC|EnsemblGenome=LOC120839115|UniProtKB=A0ACM8EKT0 A0ACM8EKT0 LOC120839115 PTHR47023:SF1 SEX PEPTIDE RECEPTOR SEX PEPTIDE RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8025978|UniProtKB=A0ACM8DGZ7 A0ACM8DGZ7 LOC8025978 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8039051|UniProtKB=A0ACM8DR86 A0ACM8DR86 IRSp53 PTHR14206:SF7 BRAIN-SPECIFIC ANGIOGENESIS INHIBITOR 1-ASSOCIATED PROTEIN 2 INSULIN RECEPTOR SUBSTRATE 53 KDA, ISOFORM A molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 positive regulation of cellular process#GO:0048522;regulation of actin filament organization#GO:0110053;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;actin filament bundle assembly#GO:0051017;regulation of supramolecular fiber organization#GO:1902903;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular component assembly#GO:0022607;positive regulation of cellular component biogenesis#GO:0044089;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;actin filament bundle organization#GO:0061572;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;positive regulation of cellular component organization#GO:0051130;regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8024681|UniProtKB=A0ACM8DIH5 A0ACM8DIH5 HSPC300 PTHR33668:SF3 PROTEIN BRICK1 PROTEIN BRICK1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of actin filament organization#GO:0110053;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956;positive regulation of cellular component biogenesis#GO:0044089;regulation of anatomical structure size#GO:0090066;regulation of actin nucleation#GO:0051125;regulation of cell projection organization#GO:0031344;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of organelle organization#GO:0033043;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;regulation of cell projection assembly#GO:0060491;regulation of biological quality#GO:0065008 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115312539|UniProtKB=A0ACM8DRU8 A0ACM8DRU8 LOC115312539 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP hydrolysis activity#GO:0016887;protein binding#GO:0005515;hydrolase activity#GO:0016787;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111 metabolic process#GO:0008152;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC8034282|UniProtKB=A0ACM8DTL6 A0ACM8DTL6 LOC8034282 PTHR11711:SF322 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR 6 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;guanyl nucleotide binding#GO:0019001 intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;vesicle-mediated transport#GO:0016192 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020 Integrin signalling pathway#P00034>Arf6#P00919;Huntington disease#P00029>ARF#P00786 IXOSC|EnsemblGenome=LOC121047144|UniProtKB=A0ACM8FED0 A0ACM8FED0 LOC121047144 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120848931|UniProtKB=A0ACM8F5U9 A0ACM8F5U9 LOC120848931 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8050902|UniProtKB=A0ACM8F795 A0ACM8F795 PTHR25480:SF0 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 73 C-MAF-INDUCING PROTEIN PH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841422|UniProtKB=A0ACM8ER73 A0ACM8ER73 LOC120841422 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8029940|UniProtKB=A0ACM8DJ49 A0ACM8DJ49 LOC8029940 PTHR23137:SF36 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN SFT2C IXOSC|EnsemblGenome=LOC121837032|UniProtKB=A0ACM8G2E5 A0ACM8G2E5 LOC121837032 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8027949|UniProtKB=A0ACM8EAJ6 A0ACM8EAJ6 LOC8027949 PTHR11232:SF17 PHOSPHOTYROSINE INTERACTION DOMAIN-CONTAINING FAMILY MEMBER CAPON-LIKE PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591 organelle#GO:0043226;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;neuron projection#GO:0043005;contractile muscle fiber#GO:0043292;membraneless organelle#GO:0043228;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;axon#GO:0030424;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120838860|UniProtKB=A0ACM8ELR5 A0ACM8ELR5 LOC120838860 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029370|UniProtKB=A0ACM8DZP8 A0ACM8DZP8 Sans PTHR24201:SF19 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 4B ISOFORM X1 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 IXOSC|EnsemblGenome=LOC8028458|UniProtKB=A0ACM8EV28 A0ACM8EV28 LOC8028458 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;chitin metabolic process#GO:0006030;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative catabolic process#GO:1901136;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC120841249|UniProtKB=A0ACM8ERA0 A0ACM8ERA0 LOC120841249 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC8037690|UniProtKB=A0ACM8ECH7 A0ACM8ECH7 LOC8037690 PTHR14969:SF14 SPHINGOSINE-1-PHOSPHATE PHOSPHOHYDROLASE SPHINGOSINE-1-PHOSPHATE PHOSPHATASE 2 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular process#GO:0009987;phosphate-containing compound metabolic process#GO:0006796;phospholipid dephosphorylation#GO:0046839;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;alcohol metabolic process#GO:0006066;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid modification#GO:0030258;dephosphorylation#GO:0016311 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8052268|UniProtKB=A0ACM8DUT5 A0ACM8DUT5 LOC8052268 PTHR13412:SF0 T-CELL IMMUNOMODULATORY PROTEIN HOMOLOG T-CELL IMMUNOMODULATORY PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115324791|UniProtKB=A0ACM8ETH1 A0ACM8ETH1 LOC115324791 PTHR24416:SF647 TYROSINE-PROTEIN KINASE RECEPTOR PROTEIN KINASE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein tyrosine kinase activity#GO:0004713;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 animal gross anatomical part developmental process#GO:0160108;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;signal transduction#GO:0007165;cellular process#GO:0009987;cell migration#GO:0016477;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115318459|UniProtKB=A0ACM8FJZ7 A0ACM8FJZ7 LOC115318459 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8035134|UniProtKB=A0ACM8FN25 A0ACM8FN25 PTHR47653:SF1 PROTEIN BARK BEETLE PROTEIN BARK BEETLE cell-cell junction maintenance#GO:0045217;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell-cell junction organization#GO:0045216;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8042417|UniProtKB=A0ACM8DKX0 A0ACM8DKX0 Vha13 PTHR12713:SF39 VACUOLAR ATP SYNTHASE SUBUNIT G V-TYPE PROTON ATPASE SUBUNIT G transport#GO:0006810;synaptic vesicle cycle#GO:0099504;developmental process#GO:0032502;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;cellular homeostasis#GO:0019725;vesicle organization#GO:0016050;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;developmental maturation#GO:0021700;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transmembrane transport#GO:0055085;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;cellular component organization#GO:0016043;homeostatic process#GO:0042592 vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane#GO:0016020;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC115309091|UniProtKB=A0ACM8DNG2 A0ACM8DNG2 LOC115309091 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8034103|UniProtKB=A0ACM8DIY1 A0ACM8DIY1 Nxt1 PTHR12612:SF9 NUCLEAR TRANSPORT FACTOR 2 NTF2-RELATED EXPORT PROTEIN 2-RELATED establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;organelle envelope#GO:0031967;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121836545|UniProtKB=A0ACM8FZ24 A0ACM8FZ24 LOC121836545 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841553|UniProtKB=A0ACM8ERH2 A0ACM8ERH2 LOC120841553 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028383|UniProtKB=A0ACM8FIQ7 A0ACM8FIQ7 LOC8028383 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8031514|UniProtKB=A0ACM8DIC3 A0ACM8DIC3 LOC8031514 PTHR11097:SF14 EXOSOME COMPLEX EXONUCLEASE RIBOSOMAL RNA PROCESSING PROTEIN EXOSOME COMPLEX COMPONENT RRP45 RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA metabolic process#GO:0016073;rRNA processing#GO:0006364;nuclear mRNA surveillance#GO:0071028;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;snRNA processing#GO:0016180;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;ribonucleoprotein complex biogenesis#GO:0022613;snRNA 3'-end processing#GO:0034472;maturation of 5.8S rRNA#GO:0000460;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of gene expression#GO:0010629;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 RNA metabolism protein#PC00031;exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC8036530|UniProtKB=A0ACM8DUB8 A0ACM8DUB8 LOC8036530 PTHR19282:SF519 TETRASPANIN TETRASPANIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8037360|UniProtKB=A0ACM8E943 A0ACM8E943 LOC8037360 PTHR46527:SF2 NUCLEOPORIN-LIKE PROTEIN 2 NUCLEOPORIN NUP42 transporter#PC00227 IXOSC|EnsemblGenome=LOC121048565|UniProtKB=A0ACM8FYU3 A0ACM8FYU3 LOC121048565 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8026652|UniProtKB=A0ACM8G5Y2 A0ACM8G5Y2 LOC8026652 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 IXOSC|EnsemblGenome=LOC115317698|UniProtKB=A0ACM8EG99 A0ACM8EG99 LOC115317698 PTHR13516:SF30 RIBONUCLEASE P SUBUNIT P25 FI09323P binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC115321748|UniProtKB=A0ACM8FBJ9 A0ACM8FBJ9 LOC115321748 PTHR21257:SF57 DELTA(14)-STEROL REDUCTASE 7-DEHYDROCHOLESTEROL REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;secondary alcohol biosynthetic process#GO:1902653;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120840372|UniProtKB=A0ACM8EPA7 A0ACM8EPA7 LOC120840372 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053994|UniProtKB=A0ACM8FR21 A0ACM8FR21 LOC8053994 PTHR23077:SF117 AAA-FAMILY ATPASE ATPASE FAMILY GENE 2 PROTEIN HOMOLOG B hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8039459|UniProtKB=A0ACM8EGK8 A0ACM8EGK8 LOC8039459 PTHR13832:SF827 PROTEIN PHOSPHATASE 2C PROTEIN PHOSPHATASE 1L hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8028664|UniProtKB=A0ACM8F3I2 A0ACM8F3I2 LOC8028664 PTHR14618:SF0 HOMEODOX-CONTAINING PROTEIN 1 HMBOX1 HOMEOBOX-CONTAINING PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC120848547|UniProtKB=A0ACM8F5V1 A0ACM8F5V1 PTHR12233:SF1 VACUOLAR PROTEIN SORTING 26 RELATED VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 26 cytosolic transport#GO:0016482;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;retromer complex#GO:0030904;vesicle#GO:0031982 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115329372|UniProtKB=A0ACM8EZN1 A0ACM8EZN1 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836820|UniProtKB=A0ACM8G1P0 A0ACM8G1P0 LOC121836820 PTHR46237:SF2 CYTOCHROME B5 REDUCTASE 4 FAMILY MEMBER CYTOCHROME B5 REDUCTASE 4 oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 superoxide metabolic process#GO:0006801;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 reductase#PC00198 IXOSC|EnsemblGenome=LOC8027579|UniProtKB=A0ACM8DRP4 A0ACM8DRP4 LOC8027579 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=LOC121834678|UniProtKB=A0ACM8FQF1 A0ACM8FQF1 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030033|UniProtKB=A0ACM8FKF6 A0ACM8FKF6 LOC8030033 PTHR24248:SF214 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR TYRAMINE_OCTOPAMINE RECEPTOR signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120837605|UniProtKB=A0ACM8EIT6 A0ACM8EIT6 LOC120837605 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN circulatory system development#GO:0072359;heart development#GO:0007507;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular process#GO:0009987;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502;post-embryonic development#GO:0009791 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115326886|UniProtKB=A0ACM8FD38 A0ACM8FD38 SREBP PTHR46062:SF1 STEROL REGULATORY ELEMENT-BINDING PROTEIN LP12374P RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC115323488|UniProtKB=A0ACM8F3H6 A0ACM8F3H6 LOC115323488 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8040571|UniProtKB=A0ACM8DMW7 A0ACM8DMW7 DNApol-alpha180 PTHR45861:SF1 DNA POLYMERASE ALPHA CATALYTIC SUBUNIT DNA POLYMERASE ALPHA CATALYTIC SUBUNIT transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;sequence-specific double-stranded DNA binding#GO:1990837;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;DNA-directed DNA polymerase activity#GO:0003887;DNA binding#GO:0003677;transferase activity#GO:0016740;sequence-specific DNA binding#GO:0043565;catalytic activity, acting on DNA#GO:0140097;DNA polymerase activity#GO:0034061;single-stranded DNA binding#GO:0003697;DNA replication origin binding#GO:0003688;binding#GO:0005488 DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA strand elongation involved in DNA replication#GO:0006271;response to stimulus#GO:0050896;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;DNA biosynthetic process#GO:0071897;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to stress#GO:0006950;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;replication fork#GO:0005657;replisome#GO:0030894;nuclear DNA-directed RNA polymerase complex#GO:0055029;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234 DNA metabolism protein#PC00009 DNA replication#P00017>Pol alpha#P00531 IXOSC|EnsemblGenome=LOC8028509|UniProtKB=A0ACM8E0J4 A0ACM8E0J4 PTHR11080:SF2 PYRAZINAMIDASE/NICOTINAMIDASE NICOTINAMIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120838968|UniProtKB=A0ACM8EL65 A0ACM8EL65 LOC120838968 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115330045|UniProtKB=A0ACM8G5I8 A0ACM8G5I8 LOC115330045 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8030391|UniProtKB=A0ACM8DZ84 A0ACM8DZ84 LOC8030391 PTHR10485:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 AT05822P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transmembrane protein transporter activity#GO:0008320 protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;protein localization to mitochondrion#GO:0070585;protein transport#GO:0015031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;mitochondrial transmembrane transport#GO:1990542;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737 transporter#PC00227 IXOSC|EnsemblGenome=LOC120850854|UniProtKB=A0ACM8FX70 A0ACM8FX70 LOC120850854 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120838895|UniProtKB=A0ACM8ELK3 A0ACM8ELK3 LOC120838895 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121045536|UniProtKB=A0ACM8FHP1 A0ACM8FHP1 LOC121045536 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043074|UniProtKB=A0ACM8DR35 A0ACM8DR35 LOC8043074 PTHR11751:SF29 ALANINE AMINOTRANSFERASE ALANINE TRANSAMINASE transferase#PC00220;transaminase#PC00216 IXOSC|EnsemblGenome=LOC8031472|UniProtKB=A0ACM8DIA3 A0ACM8DIA3 PTHR23506:SF45 GH10249P GH10249P symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;solute:sodium symporter activity#GO:0015370;chloride transmembrane transporter activity#GO:0015108;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;neurotransmitter transport#GO:0006836;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 axon#GO:0030424;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;neuron projection terminus#GO:0044306;intracellular membrane-bounded organelle#GO:0043231;terminal bouton#GO:0043195;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;organelle membrane#GO:0031090;axon terminus#GO:0043679;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular vesicle#GO:0097708;cell projection#GO:0042995;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;presynapse#GO:0098793;neuron projection#GO:0043005;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659 secondary carrier transporter#PC00258;transporter#PC00227 5HT1 type receptor mediated signaling pathway#P04373>5HT vesicular transporter#P04410;5HT4 type receptor mediated signaling pathway#P04376>5HT vesicular transporter#P04432;Adrenaline and noradrenaline biosynthesis#P00001>VAT1#P00071;5HT2 type receptor mediated signaling pathway#P04374>5HT vesicular transporter#P04418;5HT3 type receptor mediated signaling pathway#P04375>5HT vesicular transporter#P04424 IXOSC|EnsemblGenome=LOC115326609|UniProtKB=A0ACM8F0A4 A0ACM8F0A4 LOC115326609 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8023981|UniProtKB=A0ACM8FGF6 A0ACM8FGF6 gogo PTHR16311:SF3 THROMBOSPONDIN TYPE I DOMAIN-CONTAINING 1 THROMBOSPONDIN TYPE-1 DOMAIN-CONTAINING PROTEIN 1 cell periphery#GO:0071944;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115312274|UniProtKB=A0ACM8F1Y3 A0ACM8F1Y3 LOC115312274 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115333094|UniProtKB=A0ACM8EED2 A0ACM8EED2 LOC115333094 PTHR10974:SF1 FI08016P-RELATED DUF229 DOMAIN CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8029562|UniProtKB=A0ACM8EH53 A0ACM8EH53 LOC8029562 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC115326659|UniProtKB=A0ACM8EX92 A0ACM8EX92 LOC115326659 PTHR11214:SF379 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120841559|UniProtKB=A0ACM8ERT1 A0ACM8ERT1 LOC120841559 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036433|UniProtKB=A0ACM8FNT0 A0ACM8FNT0 PTHR45845:SF3 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR-RELATED PURATROPHIN-1-LIKE, ISOFORM A guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8033417|UniProtKB=A0ACM8DQH5 A0ACM8DQH5 LOC8033417 PTHR21514:SF0 AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN AP-4 COMPLEX ACCESSORY SUBUNIT TEPSIN intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;trans-Golgi network membrane#GO:0032588;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 IXOSC|EnsemblGenome=LOC120848732|UniProtKB=A0ACM8F5H1 A0ACM8F5H1 LOC120848732 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115318679|UniProtKB=A0ACM8ERF0 A0ACM8ERF0 LOC115318679 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047132|UniProtKB=A0ACM8FFS4 A0ACM8FFS4 LOC121047132 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115321589|UniProtKB=A0ACM8F3K2 A0ACM8F3K2 LOC115321589 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8040527|UniProtKB=A0ACM8FUE4 A0ACM8FUE4 LOC8040527 PTHR45614:SF315 MYB PROTEIN-RELATED MYB PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cell cycle#GO:0007049;regulation of biological process#GO:0050789;mitotic cell cycle#GO:0000278;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC121837756|UniProtKB=A0ACM8G618 A0ACM8G618 LOC121837756 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308378|UniProtKB=A0ACM8DME7 A0ACM8DME7 LOC115308380 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC121047749|UniProtKB=A0ACM8FGH4 A0ACM8FGH4 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050491|UniProtKB=A0ACM8E572 A0ACM8E572 LOC8050491 PTHR23418:SF0 ACIREDUCTONE DIOXYGENASE ACIREDUCTONE DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;sulfur compound metabolic process#GO:0006790;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121838293|UniProtKB=A0ACM8G7K8 A0ACM8G7K8 LOC121838293 PTHR10858:SF23 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE II DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cell death#GO:0008219;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC115328235|UniProtKB=A0ACM8EYZ4 A0ACM8EYZ4 LOC115328235 PTHR11214:SF411 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8040139|UniProtKB=A0ACM8DKJ0 A0ACM8DKJ0 LOC8040139 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8043400|UniProtKB=A0ACM8EKB6 A0ACM8EKB6 LOC8043400 PTHR43447:SF61 ALPHA-AMYLASE ALPHA-AMYLASE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 amylase#PC00048 IXOSC|EnsemblGenome=LOC120848499|UniProtKB=A0ACM8F656 A0ACM8F656 LOC120848499 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8036179|UniProtKB=A0ACM8DJX7 A0ACM8DJX7 LOC8036179 PTHR10029:SF3 ACYLPHOSPHATASE ACYLPHOSPHATASE-1 hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8024065|UniProtKB=A0ACM8DHW7 A0ACM8DHW7 LOC8024065 PTHR12636:SF5 NEP1/MRA1 RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE NEP1 catalytic activity, acting on a rRNA#GO:0140102;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;rRNA binding#GO:0019843;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;rRNA base methylation#GO:0070475;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;methylation#GO:0032259;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8050588|UniProtKB=A0ACM8DS18 A0ACM8DS18 LOC8050588 PTHR24221:SF503 ATP-BINDING CASSETTE SUB-FAMILY B MULTIDRUG RESISTANCE PROTEIN HOMOLOG 49-RELATED primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115314660|UniProtKB=A0ACM8ERP0 A0ACM8ERP0 LOC115314660 PTHR11177:SF144 CHITINASE CHITINASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;chitin metabolic process#GO:0006030;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115310264|UniProtKB=A0ACM8F7D8 A0ACM8F7D8 LOC115310264 PTHR24317:SF7 PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE PEROXISOMAL TRANS-2-ENOYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 cellular process#GO:0009987;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;terpenoid metabolic process#GO:0006721;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;diterpenoid metabolic process#GO:0016101;isoprenoid metabolic process#GO:0006720 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836128|UniProtKB=A0ACM8FXG9 A0ACM8FXG9 LOC121836128 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844245|UniProtKB=A0ACM8EY76 A0ACM8EY76 LOC8024621 PTHR11880:SF2 RIBOSOMAL PROTEIN S19P FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US19 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121834689|UniProtKB=A0ACM8FRM3 A0ACM8FRM3 PTHR11523:SF28 SODIUM/POTASSIUM-DEPENDENT ATPASE BETA SUBUNIT AT04468P-RELATED ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;potassium ion import across plasma membrane#GO:1990573;establishment of localization#GO:0051234;import into cell#GO:0098657;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;inorganic ion homeostasis#GO:0098771;potassium ion homeostasis#GO:0055075;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;homeostatic process#GO:0042592;export from cell#GO:0140352;inorganic ion import across plasma membrane#GO:0099587 ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation-transporting ATPase complex#GO:0090533;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8042705|UniProtKB=A0ACM8E312 A0ACM8E312 LOC8042705 PTHR11730:SF58 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;cellular process#GO:0009987;nitrogen compound transport#GO:0071705 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115322492|UniProtKB=A0ACM8FUZ6 A0ACM8FUZ6 LOC115322492 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025957|UniProtKB=A0ACM8EFM9 A0ACM8EFM9 LOC8025957 PTHR14826:SF14 ANGIOMOTIN ANGIOMOTIN_C DOMAIN-CONTAINING PROTEIN regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;organelle organization#GO:0006996;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of cell motility#GO:2000145;regulation of cell migration#GO:0030334;actin filament-based process#GO:0030029 anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;tight junction#GO:0070160;cell junction#GO:0030054;apical junction complex#GO:0043296;bicellular tight junction#GO:0005923;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell-cell junction#GO:0005911;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC115320078|UniProtKB=A0ACM8ERK8 A0ACM8ERK8 LOC115320078 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045740|UniProtKB=A0ACM8FU90 A0ACM8FU90 LOC121835491 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837893|UniProtKB=A0ACM8G0V1 A0ACM8G0V1 LOC120837893 PTHR43730:SF1 BETA-MANNOSIDASE BETA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121837797|UniProtKB=A0ACM8G562 A0ACM8G562 LOC121837797 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029889|UniProtKB=A0ACM8E9U8 A0ACM8E9U8 LOC8029889 PTHR21541:SF3 BTB POZ DOMAIN CONTAINING 12 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT SLX4 meiosis I cell cycle process#GO:0061982;nuclear division#GO:0000280;sexual reproduction#GO:0019953;reciprocal meiotic recombination#GO:0007131;organelle fission#GO:0048285;cell cycle#GO:0007049;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cell cycle process#GO:0022402;reproductive process#GO:0022414;homologous recombination#GO:0035825;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;meiotic nuclear division#GO:0140013;organelle organization#GO:0006996;resolution of meiotic recombination intermediates#GO:0000712;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC8043504|UniProtKB=A0ACM8DTE1 A0ACM8DTE1 RhoGEF64C PTHR46006:SF5 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 regulation of cell communication#GO:0010646;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC120841290|UniProtKB=A0ACM8ER91 A0ACM8ER91 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047814|UniProtKB=A0ACM8G3Q2 A0ACM8G3Q2 LOC121047814 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120841526|UniProtKB=A0ACM8ERY3 A0ACM8ERY3 LOC120841526 PTHR24208:SF127 LIM/HOMEOBOX PROTEIN LHX LIM_HOMEOBOX PROTEIN AWH DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC120848620|UniProtKB=A0ACM8F6E3 A0ACM8F6E3 LOC120848620 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315691|UniProtKB=A0ACM8G301 A0ACM8G301 LOC115315691 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120843872|UniProtKB=A0ACM8G1M8 A0ACM8G1M8 LOC120843872 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836124|UniProtKB=A0ACM8EWR9 A0ACM8EWR9 LOC120836124 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC115329653|UniProtKB=A0ACM8EA11 A0ACM8EA11 LOC115329653 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8026846|UniProtKB=A0ACM8DID7 A0ACM8DID7 LOC8026846 PTHR12236:SF79 STRUCTURAL CONSTITUENT OF CUTICLE CUTICULAR PROTEIN 64AA-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8040683|UniProtKB=A0ACM8FLN7 A0ACM8FLN7 LOC8040683 PTHR13723:SF278 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF A, ISOFORM B metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;extracellular matrix organization#GO:0030198;proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8037957|UniProtKB=A0ACM8F3K8 A0ACM8F3K8 LOC8037957 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8032044|UniProtKB=A0ACM8E7S5 A0ACM8E7S5 Dap160 PTHR46006:SF11 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR AT 64C, ISOFORM A INTERSECTIN-2B ISOFORM X1 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8026273|UniProtKB=A0ACM8ESH9 A0ACM8ESH9 LOC8026273 PTHR22625:SF61 PLEXIN HEPATOCYTE GROWTH FACTOR RECEPTOR signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;developmental process#GO:0032502;regulation of cell migration#GO:0030334;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of locomotion#GO:0040012;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;response to stimulus#GO:0050896;cell junction organization#GO:0034330;synapse assembly#GO:0007416;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell junction assembly#GO:0034329;cellular component organization#GO:0016043 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115318724|UniProtKB=A0ACM8DYD2 A0ACM8DYD2 LOC115318724 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835201|UniProtKB=A0ACM8FRX7 A0ACM8FRX7 LOC121835201 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659 regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;protein sumoylation#GO:0016925;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;protein modification by small protein conjugation or removal#GO:0070647 chromosome#GO:0005694;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 IXOSC|EnsemblGenome=LOC8033539|UniProtKB=A0ACM8FVK4 A0ACM8FVK4 Rab27 PTHR47980:SF96 LD44762P SMALL MONOMERIC GTPASE vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;intracellular vesicle#GO:0097708;cell periphery#GO:0071944;vesicle#GO:0031982 IXOSC|EnsemblGenome=LOC115320819|UniProtKB=A0ACM8E0K2 A0ACM8E0K2 NELF-B PTHR13503:SF3 NEGATIVE ELONGATION FACTOR COMPLEX MEMBER B NEGATIVE ELONGATION FACTOR B negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;stem cell differentiation#GO:0048863;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120843285|UniProtKB=A0ACM8EWV3 A0ACM8EWV3 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028036|UniProtKB=A0ACM8DJK1 A0ACM8DJK1 LOC8028036 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8038816|UniProtKB=A0ACM8DXG2 A0ACM8DXG2 LOC8038816 PTHR11227:SF18 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 3 lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;protein-macromolecule adaptor activity#GO:0030674;phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090 macroautophagy#GO:0016236;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;energy derivation by oxidation of organic compounds#GO:0015980;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;intracellular protein localization#GO:0008104;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;localization#GO:0051179;vacuole organization#GO:0007033;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;polysaccharide catabolic process#GO:0000272;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8030227|UniProtKB=A0ACM8DSP5 A0ACM8DSP5 LOC8030227 PTHR10333:SF89 INHIBITOR OF GROWTH PROTEIN INHIBITOR OF GROWTH PROTEIN histone reader activity#GO:0140566;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;chromatin-protein adaptor activity#GO:0140463 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Sin3-type complex#GO:0070822;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115309956|UniProtKB=A0ACM8DPA9 A0ACM8DPA9 LOC115309956 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120844732|UniProtKB=A0ACM8EZK9 A0ACM8EZK9 LOC120844732 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8041229|UniProtKB=A0ACM8EAG9 A0ACM8EAG9 LOC8041229 PTHR11532:SF96 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D-LIKE PROTEIN catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180 metabolic process#GO:0008152;proteolysis#GO:0006508;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 IXOSC|EnsemblGenome=LOC115333191|UniProtKB=A0ACM8F7K8 A0ACM8F7K8 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840560|UniProtKB=A0ACM8EPQ9 A0ACM8EPQ9 LOC120840560 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115317529|UniProtKB=A0ACM8F0N3 A0ACM8F0N3 LOC115317529 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115321220|UniProtKB=A0ACM8F4F0 A0ACM8F4F0 LOC115321220 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8023128|UniProtKB=A0ACM8EFI4 A0ACM8EFI4 LOC8023128 PTHR11767:SF102 INWARD RECTIFIER POTASSIUM CHANNEL INWARDLY RECTIFYING POTASSIUM CHANNEL 1, ISOFORM F-RELATED transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;ligand-gated monoatomic ion channel activity#GO:0015276;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;potassium ion import across plasma membrane#GO:1990573;import into cell#GO:0098657;establishment of localization#GO:0051234;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 IXOSC|EnsemblGenome=LOC8035162|UniProtKB=A0ACM8EF38 A0ACM8EF38 LOC8035162 PTHR43884:SF9 ACYL-COA DEHYDROGENASE COMPLEX I ASSEMBLY FACTOR ACAD9, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8050480|UniProtKB=A0ACM8DLD3 A0ACM8DLD3 AIMP1 PTHR11586:SF48 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER AARS-INTERACTING MULTIFUNCTIONAL PROTEIN 1 molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;enzyme activator activity#GO:0008047 translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA aminoacylation#GO:0043039;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 translational protein#PC00263 IXOSC|EnsemblGenome=LOC120837864|UniProtKB=A0ACM8EIK3 A0ACM8EIK3 LOC120837864 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8041089|UniProtKB=A0ACM8E756 A0ACM8E756 CdGAPr PTHR15729:SF10 CDC42 GTPASE-ACTIVATING PROTEIN GTPASE-ACTIVATING PROTEIN CDGAPR enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC120849687|UniProtKB=A0ACM8F859 A0ACM8F859 PTHR44145:SF5 DNAJ HOMOLOG SUBFAMILY A MEMBER 3, MITOCHONDRIAL DNAJ HOMOLOG L(2)TID, MITOCHONDRIAL mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115330805|UniProtKB=A0ACM8FA54 A0ACM8FA54 LOC115330805 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8052366|UniProtKB=A0ACM8FWH1 A0ACM8FWH1 LOC8052366 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8040743|UniProtKB=A0ACM8DNC6 A0ACM8DNC6 LOC8040743 PTHR14493:SF87 UNKEMPT FAMILY MEMBER RING FINGER PROTEIN UNKEMPT IXOSC|EnsemblGenome=LOC120844881|UniProtKB=A0ACM8F014 A0ACM8F014 LOC120844881 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314669|UniProtKB=A0ACM8EGZ2 A0ACM8EGZ2 LOC115314669 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120838127|UniProtKB=A0ACM8FDQ9 A0ACM8FDQ9 LOC120838127 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025479|UniProtKB=A0ACM8DT43 A0ACM8DT43 LOC8025479 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8039303|UniProtKB=A0ACM8EFQ0 A0ACM8EFQ0 Taf1 PTHR13900:SF0 TRANSCRIPTION INITIATION FACTOR TFIID TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 1 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515 cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;nucleobase-containing compound metabolic process#GO:0006139;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115325714|UniProtKB=A0ACM8E612 A0ACM8E612 LOC115325714 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115327877|UniProtKB=A0ACM8FF88 A0ACM8FF88 LOC115327877 PTHR24404:SF116 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120846244|UniProtKB=A0ACM8F150 A0ACM8F150 LOC120846244 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8034525|UniProtKB=A0ACM8E059 A0ACM8E059 LOC8034525 PTHR22957:SF27 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 13 enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;protein transport#GO:0015031;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC115314038|UniProtKB=A0ACM8EVG7 A0ACM8EVG7 LOC115314038 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8035330|UniProtKB=A0ACM8DVA6 A0ACM8DVA6 REG PTHR10660:SF2 PROTEASOME REGULATOR PA28 LD45860P enzyme activator activity#GO:0008047;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;peptidase activator activity#GO:0016504;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of protein catabolic process#GO:0042176;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of catabolic process#GO:0009894;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of proteasomal protein catabolic process#GO:0061136;regulation of mitotic cell cycle#GO:0007346;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC8053056|UniProtKB=A0ACM8EE19 A0ACM8EE19 LOC8053056 PTHR14879:SF15 CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RIFIFYLIN-LIKE PROTEIN ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;regulation of extrinsic apoptotic signaling pathway#GO:2001236;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of response to stimulus#GO:0048583;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;negative regulation of cellular process#GO:0048523;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;negative regulation of extrinsic apoptotic signaling pathway#GO:2001237;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;regulation of signaling#GO:0023051;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;negative regulation of signal transduction#GO:0009968;proteasomal protein catabolic process#GO:0010498 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121046736|UniProtKB=A0ACM8FUX0 A0ACM8FUX0 LOC121046736 PTHR36694:SF14 PASIFLORA 1, ISOFORM A-RELATED LP21121P IXOSC|EnsemblGenome=LOC120840365|UniProtKB=A0ACM8EPW3 A0ACM8EPW3 LOC120840365 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8041725|UniProtKB=A0ACM8E553 A0ACM8E553 Sf3b5 PTHR20978:SF0 SPLICING FACTOR 3B SUBUNIT 5 SPLICING FACTOR 3B SUBUNIT 5 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;U2 snRNP#GO:0005686 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8035411|UniProtKB=A0ACM8E3K0 A0ACM8E3K0 LOC8035411 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;A2-type glycerophospholipase activity#GO:0004623;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120842793|UniProtKB=A0ACM8FP95 A0ACM8FP95 PTHR24300:SF445 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 18A1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;binding#GO:0005488 cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;steroid metabolic process#GO:0008202 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8039111|UniProtKB=A0ACM8DQ02 A0ACM8DQ02 PTHR46156:SF1 CCCH ZINGC FINGER ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 3 IXOSC|EnsemblGenome=LOC115309428|UniProtKB=A0ACM8DNU4 A0ACM8DNU4 PTHR15138:SF14 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 4 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;transcription regulator complex#GO:0005667;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;Huntington disease#P00029>TAFII130#P00806;General transcription regulation#P00023>TBP-associated factors#P00658 IXOSC|EnsemblGenome=LOC120838580|UniProtKB=A0ACM8EL57 A0ACM8EL57 PTHR47333:SF8 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN FIBULIN-5 IXOSC|EnsemblGenome=LOC8036663|UniProtKB=A0ACM8EEN6 A0ACM8EEN6 LOC8036663 PTHR14700:SF0 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 2, MITOCHONDRIAL regulation of RNA metabolic process#GO:0051252;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;biological regulation#GO:0065007;mitochondrion organization#GO:0007005;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA processing#GO:0050684;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8035685|UniProtKB=A0ACM8DMT4 A0ACM8DMT4 LOC8035685 PTHR13533:SF1 N-ACETYLNEURAMINATE 9-O-ACETYLTRANSFERASE LD22456P transferase#PC00220;acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC8052080|UniProtKB=A0ACM8FF95 A0ACM8FF95 LOC8052080 PTHR16222:SF24 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH3 hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987;response to stress#GO:0006950;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;metabolic process#GO:0008152;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8030634|UniProtKB=A0ACM8DS87 A0ACM8DS87 LOC8030634 PTHR10410:SF51 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED BRCA1_BRCA2-CONTAINING COMPLEX SUBUNIT 3 deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC8052696|UniProtKB=A0ACM8DSX3 A0ACM8DSX3 DAAM PTHR45725:SF22 FORMIN HOMOLOGY 2 FAMILY MEMBER DISHEVELLED ASSOCIATED ACTIVATOR OF MORPHOGENESIS, ISOFORM D regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin filament polymerization#GO:0030833;positive regulation of protein polymerization#GO:0032273;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of cellular component biogenesis#GO:0044087;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;regulation of actin filament length#GO:0030832;positive regulation of cellular component organization#GO:0051130;regulation of biological quality#GO:0065008;positive regulation of organelle organization#GO:0010638 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC8052124|UniProtKB=A0ACM8FKB3 A0ACM8FKB3 LOC8052124 PTHR23204:SF10 CLEAVAGE AND POLYADENYLATION SPECIFIC FACTOR CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 6 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8030778|UniProtKB=A0ACM8DNG7 A0ACM8DNG7 FER PTHR24418:SF418 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE FER catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;binding#GO:0005488;signaling receptor binding#GO:0005102;non-membrane spanning protein tyrosine kinase activity#GO:0004715 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;developmental process#GO:0032502;cellular developmental process#GO:0048869;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 IXOSC|EnsemblGenome=LOC8024749|UniProtKB=A0ACM8EJM3 A0ACM8EJM3 LOC8024749 PTHR11662:SF462 SOLUTE CARRIER FAMILY 17 FI19708P1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120837593|UniProtKB=A0ACM8EIH0 A0ACM8EIH0 LOC120837593 PTHR24230:SF141 G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 8B neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120840477|UniProtKB=A0ACM8EPD5 A0ACM8EPD5 LOC120840477 PTHR24346:SF112 MAP/MICROTUBULE AFFINITY-REGULATING KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8028318|UniProtKB=A0ACM8DJP4 A0ACM8DJP4 LOC8028318 PTHR10334:SF613 CYSTEINE-RICH SECRETORY PROTEIN-RELATED PEPTIDASE INHIBITOR 16 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC121836713|UniProtKB=A0ACM8G0X9 A0ACM8G0X9 LOC121836713 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319589|UniProtKB=A0ACM8G513 A0ACM8G513 LOC115319589 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8041045|UniProtKB=A0ACM8DKL5 A0ACM8DKL5 LOC8041045 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121837342|UniProtKB=A0ACM8G4K1 A0ACM8G4K1 LOC121837342 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327215|UniProtKB=A0ACM8G7J3 A0ACM8G7J3 LOC115327215 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115322793|UniProtKB=A0ACM8E331 A0ACM8E331 LOC115322793 PTHR11972:SF208 NADPH OXIDASE NAD(P)H OXIDASE (H2O2-FORMING) catalytic activity#GO:0003824;oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity#GO:0016491 reactive oxygen species metabolic process#GO:0072593;response to stress#GO:0006950;metabolic process#GO:0008152;cellular process#GO:0009987;superoxide metabolic process#GO:0006801;response to stimulus#GO:0050896;defense response#GO:0006952 catalytic complex#GO:1902494;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;oxidase#PC00175 IXOSC|EnsemblGenome=LOC115324471|UniProtKB=A0ACM8E3Y9 A0ACM8E3Y9 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115308183|UniProtKB=A0ACM8E087 A0ACM8E087 LOC115308183 PTHR43903:SF28 NEUROLIGIN FI18641P1 protein binding#GO:0005515;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;signaling receptor binding#GO:0005102;binding#GO:0005488 establishment of localization#GO:0051234;developmental process#GO:0032502;transport#GO:0006810;synaptic vesicle cycle#GO:0099504;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;membrane organization#GO:0061024;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;system development#GO:0048731;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;synapse organization#GO:0050808;trans-synaptic signaling#GO:0099537;modulation of chemical synaptic transmission#GO:0050804;postsynapse organization#GO:0099173;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;nervous system development#GO:0007399;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;cellular localization#GO:0051641;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;endocytosis#GO:0006897;synapse assembly#GO:0007416;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;cell junction assembly#GO:0034329;cellular component organization#GO:0016043 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;cell surface#GO:0009986;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8031457|UniProtKB=A0ACM8FEW7 A0ACM8FEW7 PTHR21040:SF8 BCDNA.GH04120 HEXOSAMINIDASE D hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8030413|UniProtKB=A0ACM8FCU7 A0ACM8FCU7 LOC8030413 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024782|UniProtKB=A0ACM8DIQ1 A0ACM8DIQ1 BORCS6 PTHR13440:SF7 BLOC-1 RELATED COMPLEX SUBUNIT 6 BLOC-1 RELATED COMPLEX SUBUNIT 6 localization#GO:0051179;lysosome localization#GO:0032418;organelle localization#GO:0051640 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115310901|UniProtKB=A0ACM8FBC6 A0ACM8FBC6 LOC115310901 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8026358|UniProtKB=A0ACM8FWV5 A0ACM8FWV5 LOC8026358 PTHR24153:SF8 ESPIN FORKED, ISOFORM F protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 actin filament bundle organization#GO:0061572;cellular process#GO:0009987;actin filament bundle assembly#GO:0051017;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;cellular component assembly#GO:0022607;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629 non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115327524|UniProtKB=A0ACM8EG04 A0ACM8EG04 LOC115327524 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115319079|UniProtKB=A0ACM8F3V7 A0ACM8F3V7 LOC115319079 PTHR15254:SF2 FANCONI ANEMIA GROUP G PROTEIN FAMILY MEMBER FANCONI ANEMIA GROUP G PROTEIN DNA damage response#GO:0006974;cellular response to stress#GO:0033554;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to stimulus#GO:0050896 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8028701|UniProtKB=A0ACM8FFP6 A0ACM8FFP6 LOC8028701 PTHR45011:SF1 DAP3-BINDING CELL DEATH ENHANCER 1 DAP3-BINDING CELL DEATH ENHANCER 1 protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;kinase activator activity#GO:0019209;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular response to stress#GO:0033554;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC8036046|UniProtKB=A0ACM8FEN4 A0ACM8FEN4 TrpA1 PTHR47143:SF5 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS TRANSIENT RECEPTOR POTENTIAL ANKYRIN 1A transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 monoatomic ion transport#GO:0006811;monoatomic ion transmembrane transport#GO:0034220;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 transmembrane transporter complex#GO:1902495;cellular anatomical structure#GO:0110165;transporter complex#GO:1990351;protein-containing complex#GO:0032991;membrane protein complex#GO:0098796;membrane#GO:0016020 ion channel#PC00133 IXOSC|EnsemblGenome=LOC115309380|UniProtKB=A0ACM8DNM7 A0ACM8DNM7 LOC115309380 PTHR24381:SF470 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120849364|UniProtKB=A0ACM8F7Q7 A0ACM8F7Q7 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034673|UniProtKB=A0ACM8F7X5 A0ACM8F7X5 LOC8034673 PTHR13864:SF15 T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 HOMOLOG-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC115328421|UniProtKB=A0ACM8E810 A0ACM8E810 LOC115328421 PTHR37162:SF11 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121836124|UniProtKB=A0ACM8FXG5 A0ACM8FXG5 LOC121836124 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8023688|UniProtKB=A0ACM8DUV3 A0ACM8DUV3 Snx6 PTHR45850:SF7 SORTING NEXIN FAMILY MEMBER SORTING NEXIN 6, ISOFORM B cellular component organization#GO:0016043;endocytosis#GO:0006897;vesicle fusion#GO:0006906;organelle assembly#GO:0070925;localization#GO:0051179;vacuole organization#GO:0007033;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;lysosome organization#GO:0007040;cellular process#GO:0009987;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;phagolysosome assembly#GO:0001845;phagocytosis#GO:0006909;lytic vacuole organization#GO:0080171;transport#GO:0006810;apoptotic cell clearance#GO:0043277;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle organization#GO:0016050 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8040449|UniProtKB=A0ACM8DWJ3 A0ACM8DWJ3 LOC8040449 PTHR45956:SF6 RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8025418|UniProtKB=A0ACM8DJ83 A0ACM8DJ83 PTHR22811:SF14 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN LP01981P-RELATED protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;Golgi vesicle transport#GO:0048193;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907 Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC115332015|UniProtKB=A0ACM8G8A0 A0ACM8G8A0 LOC115332015 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120850594|UniProtKB=A0ACM8F959 A0ACM8F959 LOC120850594 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC121836398|UniProtKB=A0ACM8FZI1 A0ACM8FZI1 LOC121836398 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026178|UniProtKB=A0ACM8E0A3 A0ACM8E0A3 LOC8026178 PTHR11037:SF21 TRANSCRIPTION FACTOR CP2 GEMINI, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115331685|UniProtKB=A0ACM8ECK2 A0ACM8ECK2 LOC115331685 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836566|UniProtKB=A0ACM8FYP6 A0ACM8FYP6 LOC121836566 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8036529|UniProtKB=A0ACM8DUW3 A0ACM8DUW3 LOC8036529 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115327821|UniProtKB=A0ACM8E8T0 A0ACM8E8T0 LOC115327821 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846517|UniProtKB=A0ACM8F3F1 A0ACM8F3F1 LOC120846517 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314633|UniProtKB=A0ACM8G3S4 A0ACM8G3S4 LOC115314633 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8034065|UniProtKB=A0ACM8E3X0 A0ACM8E3X0 LOC8034065 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC120843860|UniProtKB=A0ACM8EX05 A0ACM8EX05 LOC120843860 PTHR47959:SF27 ATP-DEPENDENT RNA HELICASE RHLE-RELATED DEAD BOX ATP-DEPENDENT RNA HELICASE RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8025060|UniProtKB=A0ACM8DTV5 A0ACM8DTV5 ATP8B PTHR24092:SF190 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;transporter activity#GO:0005215;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657 Golgi organization#GO:0007030;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;lipid transport#GO:0006869;transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC115310637|UniProtKB=A0ACM8F872 A0ACM8F872 LOC115310637 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033572|UniProtKB=A0ACM8FL47 A0ACM8FL47 LOC8033572 PTHR11616:SF328 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075 sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;organic acid transport#GO:0015849;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;establishment of localization#GO:0051234;import into cell#GO:0098657 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121838384|UniProtKB=A0ACM8G7Z4 A0ACM8G7Z4 LOC121838384 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC8039644|UniProtKB=A0ACM8EMZ5 A0ACM8EMZ5 LOC8039644 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED carboxylic acid transmembrane transporter activity#GO:0046943;monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;chloride transport#GO:0006821 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8030729|UniProtKB=A0ACM8E4Z9 A0ACM8E4Z9 LOC8030729 PTHR12268:SF27 E3 UBIQUITIN-PROTEIN LIGASE KCMF1 DYSTROBREVIN, ISOFORM F cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell junction#GO:0030054;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115332927|UniProtKB=A0ACM8EX91 A0ACM8EX91 LOC115332927 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120842752|UniProtKB=A0ACM8G4L7 A0ACM8G4L7 LOC120842752 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8024240|UniProtKB=A0ACM8DI22 A0ACM8DI22 RpL10Ab PTHR23105:SF101 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN UL1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8031917|UniProtKB=A0ACM8E9A2 A0ACM8E9A2 TfIIEbeta PTHR12716:SF8 TRANSCRIPTION INITIATION FACTOR IIE, BETA SUBUNIT TRANSCRIPTION INITIATION FACTOR IIE SUBUNIT BETA binding#GO:0005488;transcription factor binding#GO:0008134;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175 DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366 intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;general transcription factor#PC00259 General transcription regulation#P00023>TFIIE#P00666;General transcription regulation#P00023>TFIIEbeta#P00659;Transcription regulation by bZIP transcription factor#P00055>TFIIEbeta#P01386;Transcription regulation by bZIP transcription factor#P00055>TFIIE#P01395 IXOSC|EnsemblGenome=LOC115318143|UniProtKB=A0ACM8ER24 A0ACM8ER24 LOC115318143 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8027648|UniProtKB=A0ACM8E3I7 A0ACM8E3I7 LOC8027648 PTHR18945:SF945 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-LIKE 1 molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215 metal ion transport#GO:0030001;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;cell communication#GO:0007154;localization#GO:0051179;monoatomic cation transport#GO:0006812;trans-synaptic signaling#GO:0099537;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic transmission, cholinergic#GO:0007271;cellular process#GO:0009987;synaptic signaling#GO:0099536;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810 protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC120842454|UniProtKB=A0ACM8ETW4 A0ACM8ETW4 LOC120842454 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115311905|UniProtKB=A0ACM8DRD6 A0ACM8DRD6 LOC115311905 PTHR13531:SF6 GEO07735P1-RELATED-RELATED TMEM (HUMAN TRANSMEMBRANE PROTEIN) HOMOLOG organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 ciliary transition zone#GO:0035869;cilium#GO:0005929;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120840835|UniProtKB=A0ACM8EQI4 A0ACM8EQI4 LOC120840835 PTHR23147:SF189 SERINE/ARGININE RICH SPLICING FACTOR SERINE AND ARGININE-RICH-SPLICING FACTOR 3A-RELATED organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear speck#GO:0016607;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115326308|UniProtKB=A0ACM8EJF6 A0ACM8EJF6 LOC115326308 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8033092|UniProtKB=A0ACM8DYD0 A0ACM8DYD0 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115313600|UniProtKB=A0ACM8G475 A0ACM8G475 LOC115313600 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115329292|UniProtKB=A0ACM8EYH7 A0ACM8EYH7 LOC115329292 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042874|UniProtKB=A0ACM8DL12 A0ACM8DL12 LOC8042874 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120838994|UniProtKB=A0ACM8EL94 A0ACM8EL94 LOC120838994 PTHR11616:SF279 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT SEROTONIN TRANSPORTER binding#GO:0005488;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;serotonin binding#GO:0051378;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;heterocyclic compound binding#GO:1901363;metal ion transmembrane transporter activity#GO:0046873;small molecule binding#GO:0036094;ion binding#GO:0043167;solute:sodium symporter activity#GO:0015370;cation binding#GO:0043169;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804 transmembrane transport#GO:0055085;cellular localization#GO:0051641;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;organic hydroxy compound transport#GO:0015850;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transmembrane transport#GO:0034220;neurotransmitter transport#GO:0006836;monoatomic cation transmembrane transport#GO:0098655;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;sodium ion transmembrane transport#GO:0035725 cell junction#GO:0030054;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;synapse#GO:0045202;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121836433|UniProtKB=A0ACM8FYN9 A0ACM8FYN9 LOC121836433 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8032597|UniProtKB=A0ACM8DMP2 A0ACM8DMP2 LOC8032597 PTHR43802:SF1 ENOYL-COA HYDRATASE IP11341P-RELATED hydratase#PC00120;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115308317|UniProtKB=A0ACM8EJG2 A0ACM8EJG2 LOC115308317 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316186|UniProtKB=A0ACM8EH59 A0ACM8EH59 LOC115316186 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8040140|UniProtKB=A0ACM8F890 A0ACM8F890 LOC8040140 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC121834023|UniProtKB=A0ACM8FMK2 A0ACM8FMK2 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843054|UniProtKB=A0ACM8EV67 A0ACM8EV67 LOC120843054 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115324405|UniProtKB=A0ACM8E4T5 A0ACM8E4T5 LOC115324405 PTHR16099:SF5 8-OXO-DGTP DIPHOSPHATES NUDT15 NUCLEOTIDE TRIPHOSPHATE DIPHOSPHATASE NUDT15 IXOSC|EnsemblGenome=LOC8038631|UniProtKB=A0ACM8EC98 A0ACM8EC98 LOC8038631 PTHR47221:SF10 FIBRINOGEN ALPHA CHAIN ANGIOPOIETIN-RELATED PROTEIN 3 IXOSC|EnsemblGenome=LOC121833476|UniProtKB=A0ACM8FKY1 A0ACM8FKY1 LOC121833476 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8041939|UniProtKB=A0ACM8FAJ2 A0ACM8FAJ2 LOC8041939 PTHR14593:SF5 WD REPEAT-CONTAINING PROTEIN 11 WD REPEAT-CONTAINING PROTEIN 11 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115319557|UniProtKB=A0ACM8EP75 A0ACM8EP75 LOC115319557 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8026336|UniProtKB=A0ACM8FUV4 A0ACM8FUV4 LOC8026336 PTHR16172:SF46 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE GH27779P cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8027178|UniProtKB=A0ACM8DXF0 A0ACM8DXF0 LOC8027178 PTHR12231:SF220 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN LACHESIN protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8043302|UniProtKB=A0ACM8DZ50 A0ACM8DZ50 LOC8043302 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120839817|UniProtKB=A0ACM8ENR8 A0ACM8ENR8 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8024200|UniProtKB=A0ACM8ET06 A0ACM8ET06 LOC8024200 PTHR11006:SF73 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 6 histone modifying activity#GO:0140993;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121834232|UniProtKB=A0ACM8FPK3 A0ACM8FPK3 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024554|UniProtKB=A0ACM8G2C3 A0ACM8G2C3 LOC8024554 PTHR11946:SF93 VALYL-TRNA SYNTHETASES VALINE--TRNA LIGASE-RELATED ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC120835977|UniProtKB=A0ACM8EQA5 A0ACM8EQA5 LOC120835977 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8041586|UniProtKB=A0ACM8FSI1 A0ACM8FSI1 LOC8041586 PTHR11347:SF206 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE HIGH AFFINITY CAMP-SPECIFIC AND IBMX-INSENSITIVE 3',5'-CYCLIC PHOSPHODIESTERASE 8 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;cyclic-nucleotide phosphodiesterase activity#GO:0004112 positive regulation of MAPK cascade#GO:0043410;positive regulation of intracellular signal transduction#GO:1902533;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of ERK1 and ERK2 cascade#GO:0070372;positive regulation of response to stimulus#GO:0048584;negative regulation of response to stimulus#GO:0048585;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;negative regulation of biological process#GO:0048519 hydrolase#PC00121;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC8038407|UniProtKB=A0ACM8EAT8 A0ACM8EAT8 LOC8038407 PTHR10853:SF11 PELOTA PROTEIN PELOTA HOMOLOG molecular sensor activity#GO:0140299;molecular function regulator activity#GO:0098772 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;translational elongation#GO:0006414;cellular component organization or biogenesis#GO:0071840;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular process#GO:0009987;gene expression#GO:0010467;RNA catabolic process#GO:0006401;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070;organelle disassembly#GO:1903008;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;rescue of stalled cytosolic ribosome#GO:0072344;regulation of biological process#GO:0050789;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;translation#GO:0006412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255 cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translation release factor#PC00225 IXOSC|EnsemblGenome=LOC8028829|UniProtKB=A0ACM8EQE1 A0ACM8EQE1 LOC8028829 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120848689|UniProtKB=A0ACM8F695 A0ACM8F695 LOC120848689 PTHR43612:SF3 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;oxidoreductase complex#GO:1990204;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC8028176|UniProtKB=A0ACM8ET87 A0ACM8ET87 LOC8028176 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136 glycosidase#PC00110;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115326625|UniProtKB=A0ACM8G3Y9 A0ACM8G3Y9 LOC115326625 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987 peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836165|UniProtKB=A0ACM8FYY1 A0ACM8FYY1 LOC121836165 PTHR35578:SF6 PROLINE-RICH TRANSMEMBRANE PROTEIN 4-RELATED PROLINE-RICH TRANSMEMBRANE PROTEIN 4 IXOSC|EnsemblGenome=LOC121836152|UniProtKB=A0ACM8FXN3 A0ACM8FXN3 LOC121836152 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030786|UniProtKB=A0ACM8E583 A0ACM8E583 LOC8030786 PTHR22950:SF349 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;L-amino acid transmembrane transporter activity#GO:0015179 localization#GO:0051179;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115313439|UniProtKB=A0ACM8EGQ6 A0ACM8EGQ6 LOC115313439 PTHR24253:SF153 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8031397|UniProtKB=A0ACM8FAW8 A0ACM8FAW8 Coq5 PTHR43591:SF116 METHYLTRANSFERASE 2-METHOXY-6-POLYPRENYL-1,4-BENZOQUINOL METHYLASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8034928|UniProtKB=A0ACM8G2V7 A0ACM8G2V7 LOC8034928 PTHR39072:SF2 RE48511P 63 KDA SPERM FLAGELLAR MEMBRANE PROTEIN IXOSC|EnsemblGenome=LOC8050623|UniProtKB=A0ACM8E9C4 A0ACM8E9C4 LOC8050623 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8036531|UniProtKB=A0ACM8DTX3 A0ACM8DTX3 LOC8036531 PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8053909|UniProtKB=A0ACM8EH27 A0ACM8EH27 LOC8053909 PTHR11071:SF594 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115330299|UniProtKB=A0ACM8EIT5 A0ACM8EIT5 LOC115330299 PTHR23245:SF25 TRNA METHYLTRANSFERASE TRNA WYBUTOSINE-SYNTHESIZING PROTEIN 2 HOMOLOG methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;tRNA methyltransferase activity#GO:0008175;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC115318372|UniProtKB=A0ACM8DXZ9 A0ACM8DXZ9 LOC115318372 PTHR44269:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED IP05441P oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8054072|UniProtKB=A0ACM8E265 A0ACM8E265 LOC8054072 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8035096|UniProtKB=A0ACM8E6Z6 A0ACM8E6Z6 LOC8035096 PTHR10219:SF25 GLYCOLIPID TRANSFER PROTEIN-RELATED RH52220P lipid carrier activity#GO:0005319;ion binding#GO:0043167;molecular carrier activity#GO:0140104;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;phospholipid transfer activity#GO:0120014;lipid transfer activity#GO:0120013;lipid binding#GO:0008289;phospholipid binding#GO:0005543;transporter activity#GO:0005215 lipid localization#GO:0010876;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular process#GO:0009987;lipid transport#GO:0006869;membrane organization#GO:0061024;ceramide transport#GO:0035627 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120840329|UniProtKB=A0ACM8ENN6 A0ACM8ENN6 LOC120840329 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8039095|UniProtKB=A0ACM8E6N4 A0ACM8E6N4 GCS2alpha PTHR22762:SF54 ALPHA-GLUCOSIDASE GLUCOSIDASE II SUBUNIT ALPHA catalytic activity#GO:0003824;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;alpha-glucosidase activity#GO:0090599;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC121836627|UniProtKB=A0ACM8G0D4 A0ACM8G0D4 LOC121836627 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8037021|UniProtKB=A0ACM8EEF1 A0ACM8EEF1 LOC8037021 PTHR16263:SF4 TETRATRICOPEPTIDE REPEAT PROTEIN 38 TETRATRICOPEPTIDE REPEAT PROTEIN 38 IXOSC|EnsemblGenome=LOC115317228|UniProtKB=A0ACM8F115 A0ACM8F115 LOC115317228 PTHR31493:SF1 NAZO FAMILY MEMBER PROTEIN C19ORF12 monoatomic ion homeostasis#GO:0050801;autophagy#GO:0006914;cellular process#GO:0009987;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;metabolic process#GO:0008152;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;catabolic process#GO:0009056;mitochondrial calcium ion homeostasis#GO:0051560;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;process utilizing autophagic mechanism#GO:0061919;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC8036660|UniProtKB=A0ACM8F2G0 A0ACM8F2G0 PTHR45080:SF42 CONTACTIN 5 IG-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cellular component organization or biogenesis#GO:0071840;cell adhesion#GO:0007155;synapse organization#GO:0050808;cell junction organization#GO:0034330;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;axon#GO:0030424 IXOSC|EnsemblGenome=LOC120836439|UniProtKB=A0ACM8FN88 A0ACM8FN88 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331374|UniProtKB=A0ACM8ECG4 A0ACM8ECG4 LOC115331374 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121835705|UniProtKB=A0ACM8FVF7 A0ACM8FVF7 LOC121835705 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8041639|UniProtKB=A0ACM8DSV3 A0ACM8DSV3 LOC8041639 PTHR45872:SF2 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D protein binding#GO:0005515;enzyme regulator activity#GO:0030234;signaling receptor binding#GO:0005102;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;G protein-coupled receptor binding#GO:0001664 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC120850061|UniProtKB=A0ACM8F944 A0ACM8F944 LOC120850061 PTHR13117:SF5 ENDOPLASMIC RETICULUM MULTISPAN TRANSMEMBRANE PROTEIN-RELATED MAN(5)GLCNAC(2)-PP-DOLICHOL TRANSLOCATION PROTEIN RFT1 lipid localization#GO:0010876;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;regulation of biological quality#GO:0065008;macromolecule localization#GO:0033036;cellular component organization#GO:0016043;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;lipid transport#GO:0006869;biological regulation#GO:0065007;membrane organization#GO:0061024;lipid translocation#GO:0034204 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8050590|UniProtKB=A0ACM8DM09 A0ACM8DM09 LOC8050590 PTHR13282:SF6 PROTEIN FAM32A PROTEIN FAM32A membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;spliceosomal complex#GO:0005681 IXOSC|EnsemblGenome=LOC8031720|UniProtKB=A0ACM8G4Z0 A0ACM8G4Z0 LOC8031720 PTHR48207:SF3 SUCCINATE--HYDROXYMETHYLGLUTARATE COA-TRANSFERASE SUCCINYL-COA:GLUTARATE COA-TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 IXOSC|EnsemblGenome=LOC8030764|UniProtKB=A0ACM8DHG9 A0ACM8DHG9 LOC8030764 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8051739|UniProtKB=A0ACM8EFL9 A0ACM8EFL9 LOC8051739 PTHR10742:SF421 FLAVIN MONOAMINE OXIDASE PEROXISOMAL N-ACETYL-SPERMINE_SPERMIDINE OXIDASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidase#PC00175 IXOSC|EnsemblGenome=LOC8042414|UniProtKB=A0ACM8DKW7 A0ACM8DKW7 LOC8042414 PTHR11893:SF41 INNEXIN INNEXIN INX2 wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell communication#GO:0007154;response to external stimulus#GO:0009605;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;detection of stimulus#GO:0051606;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;signal transduction#GO:0007165;response to radiation#GO:0009314;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 gap junction#PC00105 IXOSC|EnsemblGenome=LOC8040809|UniProtKB=A0ACM8EF13 A0ACM8EF13 LOC8040809 PTHR45752:SF212 LEUCINE-RICH REPEAT-CONTAINING CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8023354|UniProtKB=A0ACM8DNE2 A0ACM8DNE2 LOC8023354 PTHR21231:SF8 XPA-BINDING PROTEIN 1-RELATED GPN-LOOP GTPASE 1 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 G-protein#PC00020;protein-binding activity modulator#PC00095;small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120838747|UniProtKB=A0ACM8EKK0 A0ACM8EKK0 pug PTHR48099:SF5 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814 modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;biosynthetic process#GO:0009058;metabolic process#GO:0008152;tetrahydrofolate biosynthetic process#GO:0046654;tetrahydrofolate metabolic process#GO:0046653 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 IXOSC|EnsemblGenome=LOC120842319|UniProtKB=A0ACM8EUL7 A0ACM8EUL7 LOC120842319 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836044|UniProtKB=A0ACM8FWY4 A0ACM8FWY4 LOC121836044 PTHR21184:SF6 MENORIN (DENDRITIC BRANCHING PROTEIN) MENORIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8030696|UniProtKB=A0ACM8DUW8 A0ACM8DUW8 Pnn PTHR12707:SF0 PINN PININ nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC115313573|UniProtKB=A0ACM8G5B4 A0ACM8G5B4 LOC115313573 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578 phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;phosphorus metabolic process#GO:0006793;organophosphate catabolic process#GO:0046434;ceramide metabolic process#GO:0006672;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;lipid catabolic process#GO:0016042;cellular process#GO:0009987;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;extracellular region#GO:0005576;intracellular organelle#GO:0043229 phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8042924|UniProtKB=A0ACM8DKY0 A0ACM8DKY0 LOC8042924 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;protein binding#GO:0005515;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ATP-dependent activity#GO:0140657 metabolic process#GO:0008152;protein refolding#GO:0042026;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC115329681|UniProtKB=A0ACM8FXU4 A0ACM8FXU4 LOC115329681 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034387|UniProtKB=A0ACM8DJ92 A0ACM8DJ92 LOC8034387 PTHR19290:SF94 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED NEUROGENIN-3 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 developmental process#GO:0032502;sensory organ development#GO:0007423;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;neuron projection development#GO:0031175;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;cell development#GO:0048468;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC115331625|UniProtKB=A0ACM8F3R4 A0ACM8F3R4 LOC115331625 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8028039|UniProtKB=A0ACM8E708 A0ACM8E708 PTHR12250:SF0 PHOSPHATIDYLINOSITOL GLYCAN, CLASS N GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;glycolipid biosynthetic process#GO:0009247;protein maturation#GO:0051604;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 extracellular matrix glycoprotein#PC00100 IXOSC|EnsemblGenome=LOC8043626|UniProtKB=A0ACM8DV49 A0ACM8DV49 LOC8043626 PTHR21016:SF7 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 3 G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of response to stimulus#GO:0048583;response to stimulus#GO:0050896;positive regulation of Notch signaling pathway#GO:0045747;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593 IXOSC|EnsemblGenome=LOC8050424|UniProtKB=A0ACM8E3M8 A0ACM8E3M8 LOC8050424 PTHR39267:SF1 SURVIVAL MOTOR NEURON-LIKE PROTEIN 1 SURVIVAL OF MOTOR NEURON IXOSC|EnsemblGenome=LOC120836179|UniProtKB=A0ACM8FW46 A0ACM8FW46 LOC120836179 PTHR11923:SF51 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 FI02050P-RELATED cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115321603|UniProtKB=A0ACM8F6G9 A0ACM8F6G9 LOC115321603 PTHR45712:SF22 AGAP008170-PA LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 4 IXOSC|EnsemblGenome=LOC115314808|UniProtKB=A0ACM8FDM4 A0ACM8FDM4 LOC115314808 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322854|UniProtKB=A0ACM8FVP4 A0ACM8FVP4 LOC115322854 PTHR11829:SF411 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L2 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC115331665|UniProtKB=A0ACM8FCI1 A0ACM8FCI1 LOC115331665 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;chitin metabolic process#GO:0006030;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041115|UniProtKB=A0ACM8FRJ5 A0ACM8FRJ5 LOC8041115 PTHR24198:SF202 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ANKYRIN REPEAT AND SAM DOMAIN-CONTAINING PROTEIN 6 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115318370|UniProtKB=A0ACM8G0X3 A0ACM8G0X3 LOC115318370 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8031823|UniProtKB=A0ACM8DQJ9 A0ACM8DQJ9 Atu PTHR23146:SF0 LEO1 PROTEIN RNA POLYMERASE-ASSOCIATED PROTEIN LEO1 transcription coregulator activity#GO:0003712;RNA polymerase binding#GO:0070063;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121047021|UniProtKB=A0ACM8FFG0 A0ACM8FFG0 LOC121047021 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8039725|UniProtKB=A0ACM8E2J6 A0ACM8E2J6 LOC8039725 PTHR10003:SF71 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN]-RELATED oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;copper ion binding#GO:0005507;catalytic activity#GO:0003824;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular detoxification#GO:1990748;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to toxic substance#GO:0009636;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;response to reactive oxygen species#GO:0000302;response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;cellular process#GO:0009987;response to stress#GO:0006950;detoxification#GO:0098754;cellular response to toxic substance#GO:0097237;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8032376|UniProtKB=A0ACM8DY32 A0ACM8DY32 LOC8032376 PTHR21575:SF12 PROTEIN HID1 PROTEIN HID1 vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;developmental process#GO:0032502;endomembrane system organization#GO:0010256;developmental maturation#GO:0021700;anatomical structure maturation#GO:0071695;Golgi organization#GO:0007030;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 Golgi stack#GO:0005795;cytosol#GO:0005829;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi cisterna#GO:0031985;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8026767|UniProtKB=A0ACM8DQN2 A0ACM8DQN2 LOC8026767 PTHR22780:SF4 ADAPTIN, ALPHA/GAMMA/EPSILON AP-2 COMPLEX SUBUNIT ALPHA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 transport#GO:0006810;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;receptor-mediated endocytosis#GO:0006898;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897 vesicle coat#GO:0030120;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;organelle#GO:0043226;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;coated membrane#GO:0048475;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;endomembrane system#GO:0012505;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane coat#GO:0030117 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 IXOSC|EnsemblGenome=LOC8038211|UniProtKB=A0ACM8DPM0 A0ACM8DPM0 LOC8038211 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8027348|UniProtKB=A0ACM8DQG3 A0ACM8DQG3 LOC8027348 PTHR45626:SF50 TRANSCRIPTION TERMINATION FACTOR 2-RELATED TRANSCRIPTION TERMINATION FACTOR 2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 Transcription regulation by bZIP transcription factor#P00055>TTF2#P01389 IXOSC|EnsemblGenome=LOC120838474|UniProtKB=A0ACM8EJW1 A0ACM8EJW1 LOC120838474 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833555|UniProtKB=A0ACM8FKC7 A0ACM8FKC7 LOC121833555 PTHR12984:SF16 SCY1-RELATED S/T PROTEIN KINASE-LIKE BLACK MATCH, ISOFORM H non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8037348|UniProtKB=A0ACM8FYI6 A0ACM8FYI6 LOC8037348 PTHR46097:SF3 G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP ARF GTPASE-ACTIVATING PROTEIN GIT binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 brain development#GO:0007420;synaptic vesicle recycling#GO:0036465;multicellular organismal process#GO:0032501;vesicle-mediated transport#GO:0016192;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;nervous system development#GO:0007399;head development#GO:0060322;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;multicellular organism development#GO:0007275;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;animal organ development#GO:0048513;regulation of small GTPase mediated signal transduction#GO:0051056;developmental process#GO:0032502;regulation of G protein-coupled receptor signaling pathway#GO:0008277;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;regulation of response to stimulus#GO:0048583;central nervous system development#GO:0007417;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;localization#GO:0051179;cellular localization#GO:0051641;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of intracellular signal transduction#GO:1902531;animal gross anatomical part developmental process#GO:0160108;regulation of signaling#GO:0023051 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 IXOSC|EnsemblGenome=LOC120844250|UniProtKB=A0ACM8EXX1 A0ACM8EXX1 LOC120844250 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027778|UniProtKB=A0ACM8EQN5 A0ACM8EQN5 LOC8027778 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8029808|UniProtKB=A0ACM8F214 A0ACM8F214 LOC8029808 PTHR21324:SF2 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED CWH43-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8039603|UniProtKB=A0ACM8DKC6 A0ACM8DKC6 LOC8039603 PTHR13232:SF10 NAD(P)H-HYDRATE EPIMERASE NAD(P)H-HYDRATE EPIMERASE epimerase/racemase#PC00096;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8032745|UniProtKB=A0ACM8EAM1 A0ACM8EAM1 Arl6IP1 PTHR20952:SF0 ADP-RIBOSYLATION-LIKE FACTOR 6-INTERACTING PROTEIN ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6-INTERACTING PROTEIN 1 cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum membrane organization#GO:0090158;endoplasmic reticulum tubular network organization#GO:0071786;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum tubular network#GO:0071782;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC115316462|UniProtKB=A0ACM8DWF3 A0ACM8DWF3 LOC115316462 PTHR10265:SF45 CYCLIN-DEPENDENT KINASE INHIBITOR 1 DACAPO molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;cyclin-dependent protein serine/threonine kinase inhibitor activity#GO:0004861;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase inhibitor activity#GO:0004860;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase inhibitor activity#GO:0019210 negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;negative regulation of cell cycle#GO:0045786;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;regulation of G1/S transition of mitotic cell cycle#GO:2000045 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 kinase inhibitor#PC00139;kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC120844098|UniProtKB=A0ACM8EXV0 A0ACM8EXV0 LOC120844098 PTHR21344:SF1 RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA RAL GTPASE-ACTIVATING PROTEIN SUBUNIT BETA nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 IXOSC|EnsemblGenome=LOC120836711|UniProtKB=A0ACM8EFL7 A0ACM8EFL7 LOC120836711 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115332642|UniProtKB=A0ACM8FYZ1 A0ACM8FYZ1 LOC115332642 PTHR43245:SF51 BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA HYDROXY-DELTA-5-STEROID DEHYDROGENASE, 3 BETA- AND STEROID DELTA-ISOMERASE 1 IXOSC|EnsemblGenome=LOC121837492|UniProtKB=A0ACM8G501 A0ACM8G501 LOC121837492 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC chromatin binding#GO:0003682;binding#GO:0005488 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;transferase complex#GO:1990234;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;intracellular membrane-bounded organelle#GO:0043231;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8033664|UniProtKB=A0ACM8DUK1 A0ACM8DUK1 thoc6 PTHR44411:SF1 THO COMPLEX SUBUNIT 6 HOMOLOG THO COMPLEX SUBUNIT 6 nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;nucleocytoplasmic transport#GO:0006913;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;biosynthetic process#GO:0009058;gene expression#GO:0010467;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8026133|UniProtKB=A0ACM8E105 A0ACM8E105 LOC8026133 PTHR18884:SF57 SEPTIN CELL DIVISION CONTROL PROTEIN 10 hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 cytokinesis#GO:0000910;intracellular protein localization#GO:0008104;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;cellular process#GO:0009987;cell division#GO:0051301;cell cycle process#GO:0022402;cell cycle#GO:0007049;macromolecule localization#GO:0033036 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cell periphery#GO:0071944;cell cortex#GO:0005938;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cell division site#GO:0032153;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC115309509|UniProtKB=A0ACM8DNX0 A0ACM8DNX0 LOC115309509 PTHR18902:SF32 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED FI04457P-RELATED cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8037357|UniProtKB=A0ACM8E7Q9 A0ACM8E7Q9 LOC8037357 PTHR14899:SF0 G KINASE ANCHORING PROTEIN 1 G KINASE-ANCHORING PROTEIN 1 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115309341|UniProtKB=A0ACM8DNR6 A0ACM8DNR6 LOC115309341 PTHR46830:SF2 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220 IXOSC|EnsemblGenome=LOC121835169|UniProtKB=A0ACM8FTP1 A0ACM8FTP1 LOC121835169 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115332180|UniProtKB=A0ACM8EE99 A0ACM8EE99 LOC115332180 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115317492|UniProtKB=A0ACM8DXU8 A0ACM8DXU8 LOC115317492 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8029344|UniProtKB=A0ACM8DI19 A0ACM8DI19 Rae1 PTHR10971:SF11 MRNA EXPORT FACTOR AND BUB3 MRNA EXPORT FACTOR RAE1 protein binding#GO:0005515;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;ubiquitin binding#GO:0043130 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;nitrogen compound transport#GO:0071705;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;cellular component organization#GO:0016043;establishment of RNA localization#GO:0051236;nucleobase-containing compound transport#GO:0015931;transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery#GO:0000972;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657 organelle envelope#GO:0031967;nucleus#GO:0005634;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8043776|UniProtKB=A0ACM8DGY0 A0ACM8DGY0 LOC8043776 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115323830|UniProtKB=A0ACM8ERF3 A0ACM8ERF3 LOC115323830 PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;spindle pole#GO:0000922;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;membraneless organelle#GO:0043228;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115315552|UniProtKB=A0ACM8DUV6 A0ACM8DUV6 LOC115315552 PTHR15741:SF37 BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR LD38259P cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121833345|UniProtKB=A0ACM8FLI5 A0ACM8FLI5 LOC121833345 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031048|UniProtKB=A0ACM8DMK3 A0ACM8DMK3 LOC8031048 PTHR24067:SF360 UBIQUITIN-CONJUGATING ENZYME E2 N-TERMINAL E2 UBIQUITIN-CONJUGATING ENZYME cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121837668|UniProtKB=A0ACM8G458 A0ACM8G458 LOC121837668 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115322210|UniProtKB=A0ACM8G245 A0ACM8G245 LOC115322210 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115324567|UniProtKB=A0ACM8FW49 A0ACM8FW49 LOC115324567 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834175|UniProtKB=A0ACM8FPD5 A0ACM8FPD5 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;homologous recombination#GO:0035825;reproductive process#GO:0022414;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;response to stimulus#GO:0050896;cell cycle process#GO:0022402;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8052470|UniProtKB=A0ACM8E2H8 A0ACM8E2H8 Timp PTHR11844:SF25 METALLOPROTEASE INHIBITOR TISSUE INHIBITOR OF METALLOPROTEINASE enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;regulation of proteolysis#GO:0030162;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120836099|UniProtKB=A0ACM8FRC3 A0ACM8FRC3 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115328516|UniProtKB=A0ACM8EXK9 A0ACM8EXK9 LOC115328516 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120846625|UniProtKB=A0ACM8FIE4 A0ACM8FIE4 LOC120846625 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115329521|UniProtKB=A0ACM8E9M4 A0ACM8E9M4 LOC115329521 PTHR43778:SF4 PYRUVATE CARBOXYLASE PYRUVATE CARBOXYLASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 glucose metabolic process#GO:0006006;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;carbohydrate biosynthetic process#GO:0016051;small molecule metabolic process#GO:0044281;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 ligase#PC00142;metabolite interconversion enzyme#PC00262 Pyruvate metabolism#P02772>Pyruvate Carboxylase#P03140 IXOSC|EnsemblGenome=LOC121834165|UniProtKB=A0ACM8FN00 A0ACM8FN00 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8024579|UniProtKB=A0ACM8EB08 A0ACM8EB08 PTHR24416:SF617 TYROSINE-PROTEIN KINASE RECEPTOR PROTEIN KINASE DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115310974|UniProtKB=A0ACM8DQ84 A0ACM8DQ84 LOC115310974 PTHR12155:SF41 SCHLAFEN SCHLAFEN ALBA-2 DOMAIN-CONTAINING PROTEIN endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC8042210|UniProtKB=A0ACM8DSA4 A0ACM8DSA4 LOC8042210 PTHR16537:SF1 SJOEGREN SYNDROME/SCLERODERMA AUTOANTIGEN 1 PROTEIN ZNRD2 IXOSC|EnsemblGenome=LOC8029005|UniProtKB=A0ACM8DVI1 A0ACM8DVI1 LOC8029005 PTHR13317:SF5 TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG TRANSMEMBRANE ANTERIOR POSTERIOR TRANSFORMATION PROTEIN 1 HOMOLOG regulation of organelle assembly#GO:1902115;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;regulation of cell projection organization#GO:0031344;regulation of cilium assembly#GO:1902017;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;positive regulation of cell projection organization#GO:0031346;regulation of cell projection assembly#GO:0060491;positive regulation of organelle organization#GO:0010638 endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;microtubule organizing center#GO:0005815;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cilium#GO:0005929;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 IXOSC|EnsemblGenome=LOC8035684|UniProtKB=A0ACM8DUH9 A0ACM8DUH9 PTHR12210:SF202 DULLARD PROTEIN PHOSPHATASE PHOSPHATASE HERZOG catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC120840695|UniProtKB=A0ACM8EP86 A0ACM8EP86 LOC120840695 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843150|UniProtKB=A0ACM8EV93 A0ACM8EV93 LOC120843150 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8033709|UniProtKB=A0ACM8DSD6 A0ACM8DSD6 LOC8033709 PTHR16243:SF2 BTG3-ASSOCIATED NUCLEAR PROTEIN BANP PROTEIN BANP IXOSC|EnsemblGenome=LOC120838102|UniProtKB=A0ACM8EJT9 A0ACM8EJT9 LOC120838102 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031953|UniProtKB=A0ACM8EE48 A0ACM8EE48 CkIIalpha PTHR24054:SF0 CASEIN KINASE II SUBUNIT ALPHA CASEIN KINASE II SUBUNIT ALPHA catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 IXOSC|EnsemblGenome=LOC8031895|UniProtKB=A0ACM8G7R0 A0ACM8G7R0 LOC8031895 PTHR11972:SF175 NADPH OXIDASE DUAL OXIDASE oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor#GO:0050664;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on NAD(P)H#GO:0016651 defense response#GO:0006952;response to stimulus#GO:0050896;superoxide metabolic process#GO:0006801;cellular process#GO:0009987;metabolic process#GO:0008152;response to stress#GO:0006950;reactive oxygen species metabolic process#GO:0072593 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;oxidoreductase complex#GO:1990204;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 oxidase#PC00175;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115312058|UniProtKB=A0ACM8FIV0 A0ACM8FIV0 LOC115312058 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120844489|UniProtKB=A0ACM8G7B0 A0ACM8G7B0 LOC120844489 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8023452|UniProtKB=A0ACM8DH59 A0ACM8DH59 LOC8023452 PTHR19302:SF33 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 5 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;sexual reproduction#GO:0019953;organelle assembly#GO:0070925;reproductive process#GO:0022414;cytoplasmic microtubule organization#GO:0031122;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;spindle assembly#GO:0051225;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8023678|UniProtKB=A0ACM8DUF3 A0ACM8DUF3 LOC8023678 PTHR23104:SF17 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8038768|UniProtKB=A0ACM8DK83 A0ACM8DK83 LOC8038768 PTHR10696:SF55 GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 biosynthetic process#GO:0009058;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydroxylase#PC00122;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8051923|UniProtKB=A0ACM8DLK7 A0ACM8DLK7 LOC8051923 PTHR31996:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 115 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA22 biological regulation#GO:0065007;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;vacuolar acidification#GO:0007035;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453 endoplasmic reticulum#GO:0005783;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting V-type ATPase complex#GO:0033176;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8042229|UniProtKB=A0ACM8E8T9 A0ACM8E8T9 Gapvd1 PTHR23101:SF25 RAB GDP/GTP EXCHANGE FACTOR GTPASE-ACTIVATING PROTEIN AND VPS9 DOMAIN-CONTAINING PROTEIN 1 GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515 vesicle#GO:0031982;cytosol#GO:0005829;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115310679|UniProtKB=A0ACM8FZR2 A0ACM8FZR2 LOC115310679 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8026212|UniProtKB=A0ACM8EPR8 A0ACM8EPR8 LOC8026212 PTHR10751:SF29 GUANYLATE BINDING PROTEIN ATLASTIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization#GO:0016043;organelle organization#GO:0006996;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 heterotrimeric G-protein#PC00117;G-protein#PC00020 IXOSC|EnsemblGenome=LOC8028554|UniProtKB=A0ACM8FBG9 A0ACM8FBG9 LOC8028554 PTHR13906:SF14 PORCUPINE LYSOPHOSPHOLIPID ACYLTRANSFERASE 5 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organophosphate biosynthetic process#GO:0090407;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;lipid modification#GO:0030258;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biosynthetic process#GO:0009058;phosphatidylcholine biosynthetic process#GO:0006656;phosphatidylcholine metabolic process#GO:0046470;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637 membrane#GO:0016020;cellular anatomical structure#GO:0110165 acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC121838036|UniProtKB=A0ACM8G7B8 A0ACM8G7B8 LOC121838036 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8038206|UniProtKB=A0ACM8DU53 A0ACM8DU53 LOC8038206 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115330532|UniProtKB=A0ACM8EHI4 A0ACM8EHI4 LOC115330532 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC121835372|UniProtKB=A0ACM8FUU2 A0ACM8FUU2 LOC121835372 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein refolding#GO:0042026;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Hsp70 family chaperone#PC00027;chaperone#PC00072 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC120837669|UniProtKB=A0ACM8FV68 A0ACM8FV68 LOC120837669 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8037036|UniProtKB=A0ACM8E988 A0ACM8E988 LOC8037036 PTHR21257:SF57 DELTA(14)-STEROL REDUCTASE 7-DEHYDROCHOLESTEROL REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;sterol biosynthetic process#GO:0016126;biosynthetic process#GO:0009058;steroid metabolic process#GO:0008202;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC120843258|UniProtKB=A0ACM8EVP7 A0ACM8EVP7 LOC120843258 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8043228|UniProtKB=A0ACM8DS08 A0ACM8DS08 HGTX PTHR24340:SF35 HOMEOBOX PROTEIN NKX HGTX, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8038470|UniProtKB=A0ACM8FLU6 A0ACM8FLU6 LOC8038470 PTHR19325:SF577 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING HIG-ANCHORING SCAFFOLD PROTEIN, ISOFORM G complement component#PC00078;defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8043419|UniProtKB=A0ACM8DYA5 A0ACM8DYA5 LOC8043419 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053569|UniProtKB=A0ACM8DL95 A0ACM8DL95 LOC8053569 PTHR23316:SF87 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 protein localization to organelle#GO:0033365;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nucleocytoplasmic transport#GO:0006913;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 transporter#PC00227 IXOSC|EnsemblGenome=LOC115324246|UniProtKB=A0ACM8ELI2 A0ACM8ELI2 cindr PTHR14167:SF92 SH3 DOMAIN-CONTAINING SH3 DOMAIN-CONTAINING PROTEIN molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120841517|UniProtKB=A0ACM8ESU5 A0ACM8ESU5 LOC120841517 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837738|UniProtKB=A0ACM8G691 A0ACM8G691 LOC121837738 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8039001|UniProtKB=A0ACM8E3S3 A0ACM8E3S3 LOC8039001 PTHR10390:SF61 HOMEOBOX PROTEIN SIX HOMEOBOX DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8050721|UniProtKB=A0ACM8FCF0 A0ACM8FCF0 LOC8050721 PTHR48414:SF1 POP5 HOMOLOG, RIBONUCLEASE P_MRP SUBUNIT RIBONUCLEASE P_MRP PROTEIN SUBUNIT POP5 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 organelle lumen#GO:0043233;organelle#GO:0043226;multimeric ribonuclease P complex#GO:0030681;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleolar ribonuclease P complex#GO:0005655;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;ribonuclease MRP complex#GO:0000172;intracellular membraneless organelle#GO:0043232;endonuclease complex#GO:1905348;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC8030841|UniProtKB=A0ACM8DHL4 A0ACM8DHL4 LOC8030841 PTHR23023:SF317 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120839601|UniProtKB=A0ACM8EMD7 A0ACM8EMD7 LOC120839601 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839249|UniProtKB=A0ACM8EM80 A0ACM8EM80 LOC120839249 PTHR11596:SF96 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115317412|UniProtKB=A0ACM8F1I9 A0ACM8F1I9 LOC115317412 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8032965|UniProtKB=A0ACM8DH99 A0ACM8DH99 RpS25 PTHR12850:SF5 40S RIBOSOMAL PROTEIN S25 SMALL RIBOSOMAL SUBUNIT PROTEIN ES25 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8025306|UniProtKB=A0ACM8F7A3 A0ACM8F7A3 LOC8025306 PTHR14024:SF49 PERILIPIN LIPID STORAGE DROPLETS SURFACE-BINDING PROTEIN 1 regulation of localization#GO:0032879;lipid storage#GO:0019915;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;lipid droplet#GO:0005811;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053331|UniProtKB=A0ACM8DL88 A0ACM8DL88 LOC8053331 PTHR45695:SF42 LEUCOKININ RECEPTOR-RELATED GALANIN-LIKE G PROTEIN-COUPLED RECEPTOR NPR-9 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8039912|UniProtKB=A0ACM8DQT8 A0ACM8DQT8 Cpsf5 PTHR13047:SF0 PRE-MRNA CLEAVAGE FACTOR IM, 25KD SUBUNIT CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 5 mRNA 3'-UTR binding#GO:0003730;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 nucleus#GO:0005634;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8035376|UniProtKB=A0ACM8DJT9 A0ACM8DJT9 LOC8035376 PTHR10340:SF63 SPHINGOMYELIN PHOSPHODIESTERASE METALLOPHOS DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC115330624|UniProtKB=A0ACM8EB71 A0ACM8EB71 LOC115330624 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8031955|UniProtKB=A0ACM8DIZ3 A0ACM8DIZ3 PTHR23305:SF11 OBG GTPASE FAMILY OBG-LIKE ATPASE 1 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 G-protein#PC00020 IXOSC|EnsemblGenome=LOC8036372|UniProtKB=A0ACM8E163 A0ACM8E163 LOC8036372 PTHR22619:SF0 ZINC FINGER SWIM DOMAIN CONTAINING PROTEIN 4, 5, 6 ZSWIM4-8 C-TERMINAL DOMAIN-CONTAINING PROTEIN Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115310342|UniProtKB=A0ACM8E1T1 A0ACM8E1T1 LOC115310342 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115328817|UniProtKB=A0ACM8G3V7 A0ACM8G3V7 LOC115328817 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837733|UniProtKB=A0ACM8G4K7 A0ACM8G4K7 LOC121837733 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051174|UniProtKB=A0ACM8DMS4 A0ACM8DMS4 LOC8051174 PTHR12411:SF16 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN B catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;lysosome#GO:0005764 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115327922|UniProtKB=A0ACM8EJ64 A0ACM8EJ64 LOC115327922 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311462|UniProtKB=A0ACM8DQS1 A0ACM8DQS1 LOC115311462 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115331001|UniProtKB=A0ACM8ECX9 A0ACM8ECX9 LOC115331001 PTHR46970:SF2 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120839814|UniProtKB=A0ACM8EMU8 A0ACM8EMU8 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031691|UniProtKB=A0ACM8G2B9 A0ACM8G2B9 LOC8031691 PTHR24394:SF67 ZINC FINGER PROTEIN MYONEURIN DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120841569|UniProtKB=A0ACM8ESZ4 A0ACM8ESZ4 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051490|UniProtKB=A0ACM8ECY7 A0ACM8ECY7 Rheb PTHR24070:SF226 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY GTP-BINDING PROTEIN RHEB HOMOLOG hydrolase activity#GO:0016787;kinase activator activity#GO:0019209;GTPase activity#GO:0003924;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;protein kinase activator activity#GO:0030295;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;hydrolase activity, acting on acid anhydrides#GO:0016817;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;positive regulation of TOR signaling#GO:0032008;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;regulation of TORC1 signaling#GO:1903432;positive regulation of TORC1 signaling#GO:1904263;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;regulation of signal transduction#GO:0009966 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 small GTPase#PC00208 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;p53 pathway by glucose deprivation#P04397>Rheb#P04642;TGF-beta signaling pathway#P00052>Ras-GDP#P01291 IXOSC|EnsemblGenome=LOC115327195|UniProtKB=A0ACM8G3Q4 A0ACM8G3Q4 LOC115327195 PTHR11610:SF200 LIPASE FI22312P1 lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120850119|UniProtKB=A0ACM8F9F3 A0ACM8F9F3 LOC120850119 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8034933|UniProtKB=A0ACM8DYZ1 A0ACM8DYZ1 Atac3 PTHR24171:SF8 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1 IXOSC|EnsemblGenome=LOC115316327|UniProtKB=A0ACM8EXM6 A0ACM8EXM6 LOC115316327 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8033321|UniProtKB=A0ACM8E6Z2 A0ACM8E6Z2 LOC8033321 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121835331|UniProtKB=A0ACM8FUI1 A0ACM8FUI1 LOC121835331 PTHR11125:SF7 SUPPRESSOR OF TY 5 TRANSCRIPTION ELONGATION FACTOR SPT5 binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351 intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC121835443|UniProtKB=A0ACM8FTA2 A0ACM8FTA2 LOC121835443 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC115331983|UniProtKB=A0ACM8EIE7 A0ACM8EIE7 LOC115331983 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8029921|UniProtKB=A0ACM8G262 A0ACM8G262 LOC8029921 PTHR21010:SF3 AGAP001581-PA DAXX IXOSC|EnsemblGenome=LOC8051349|UniProtKB=A0ACM8FHA0 A0ACM8FHA0 LOC8051349 PTHR46150:SF3 RHO GTPASE-ACTIVATING PROTEIN 100F RHO GTPASE-ACTIVATING PROTEIN 100F enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of Ras protein signal transduction#GO:0046578;regulation of small GTPase mediated signal transduction#GO:0051056;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell migration#GO:0016477 plasma membrane region#GO:0098590;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;synaptic membrane#GO:0097060 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC115310778|UniProtKB=A0ACM8G596 A0ACM8G596 LOC115310778 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120841261|UniProtKB=A0ACM8ESA9 A0ACM8ESA9 LOC120841261 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313314|UniProtKB=A0ACM8FJY3 A0ACM8FJY3 LOC115313314 PTHR23151:SF94 DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX, MITOCHONDRIAL acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;acetyl-CoA metabolic process#GO:0006084;oxoacid metabolic process#GO:0043436;purine-containing compound biosynthetic process#GO:0072522 mitochondrion#GO:0005739;oxidoreductase complex#GO:1990204;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;membrane-bounded organelle#GO:0043227 acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC120837139|UniProtKB=A0ACM8FDK8 A0ACM8FDK8 LOC120847939 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847836|UniProtKB=A0ACM8F501 A0ACM8F501 LOC120847836 PTHR11699:SF310 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE (NAD(+)) oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;catabolic process#GO:0009056;aldehyde catabolic process#GO:0046185 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC8026578|UniProtKB=A0ACM8DHZ4 A0ACM8DHZ4 LOC8026578 PTHR10041:SF11 COLIPASE SUBFAMILY NOT NAMED protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC121834735|UniProtKB=A0ACM8FQN8 A0ACM8FQN8 LOC121834735 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC115313823|UniProtKB=A0ACM8EQS0 A0ACM8EQS0 LOC115313823 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8050471|UniProtKB=A0ACM8DLE6 A0ACM8DLE6 LOC8050471 PTHR22780:SF4 ADAPTIN, ALPHA/GAMMA/EPSILON AP-2 COMPLEX SUBUNIT ALPHA molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;clathrin-dependent endocytosis#GO:0072583;receptor-mediated endocytosis#GO:0006898;establishment of localization#GO:0051234;import into cell#GO:0098657;localization#GO:0051179;transport#GO:0006810 cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;plasma membrane#GO:0005886;endomembrane system#GO:0012505;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane coat#GO:0030117;vesicle coat#GO:0030120;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;clathrin vesicle coat#GO:0030125;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;intracellular vesicle#GO:0097708;clathrin-coated pit#GO:0005905;coated vesicle membrane#GO:0030662;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endocytic vesicle#GO:0030139;coated vesicle#GO:0030135;coated membrane#GO:0048475 membrane traffic protein#PC00150 Huntington disease#P00029>alpha-Adaptin#P00782 IXOSC|EnsemblGenome=LOC121835467|UniProtKB=A0ACM8FVB5 A0ACM8FVB5 LOC121835467 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314718|UniProtKB=A0ACM8DU56 A0ACM8DU56 Prosalpha5 PTHR11599:SF14 PROTEASOME SUBUNIT ALPHA/BETA PROTEASOME SUBUNIT ALPHA TYPE-5 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369 protease#PC00190;protein modifying enzyme#PC00260 Parkinson disease#P00049>20S proteasome#P01227 IXOSC|EnsemblGenome=LOC120846117|UniProtKB=A0ACM8F1J7 A0ACM8F1J7 mRpS28 PTHR13447:SF2 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S28 SMALL RIBOSOMAL SUBUNIT PROTEIN BS1M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8030082|UniProtKB=A0ACM8EEF5 A0ACM8EEF5 LOC8030082 PTHR10856:SF0 CORONIN CORONIN protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;actin filament#GO:0005884;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8027351|UniProtKB=A0ACM8DIY5 A0ACM8DIY5 LOC8027351 PTHR39069:SF11 ECDYSONE-INDUCIBLE GENE E1, ISOFORM A EB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042231|UniProtKB=A0ACM8FCK3 A0ACM8FCK3 TfIIB PTHR11618:SF85 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION INITIATION FACTOR IIB protein binding#GO:0005515;binding#GO:0005488;transcription factor binding#GO:0008134 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 general transcription factor#PC00259 General transcription regulation#P00023>TFIIB#P00668;Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397 IXOSC|EnsemblGenome=LOC8024816|UniProtKB=A0ACM8FG19 A0ACM8FG19 ari-2 PTHR22771:SF4 CULLIN AND GALACTOSE-BINDING DOMAIN-CONTAINING RBR-TYPE E3 UBIQUITIN TRANSFERASE structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of cell cycle#GO:0051726;catabolic process#GO:0009056;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of nuclear division#GO:0051783;cellular process#GO:0009987;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic nuclear division#GO:0007088;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 IXOSC|EnsemblGenome=LOC8038654|UniProtKB=A0ACM8FUP4 A0ACM8FUP4 LOC8038654 PTHR10501:SF49 U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A/U2 SMALL NUCLEAR RIBONUCLEOPROTEIN B PROTEIN COUCH POTATO binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8043538|UniProtKB=A0ACM8E5P2 A0ACM8E5P2 LOC8043538 PTHR14319:SF3 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 TRANSMEMBRANE PROTEIN-LIKE PROTEIN cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115328615|UniProtKB=A0ACM8G913 A0ACM8G913 LOC120848623 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8034715|UniProtKB=A0ACM8DY09 A0ACM8DY09 ste14 PTHR12714:SF9 PROTEIN-S ISOPRENYLCYSTEINE O-METHYLTRANSFERASE PROTEIN-S-ISOPRENYLCYSTEINE O-METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;O-methyltransferase activity#GO:0008171;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8042143|UniProtKB=A0ACM8DKW3 A0ACM8DKW3 LOC8042143 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8023891|UniProtKB=A0ACM8DHP5 A0ACM8DHP5 LOC8023891 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120841211|UniProtKB=A0ACM8ER26 A0ACM8ER26 LOC120841211 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838517|UniProtKB=A0ACM8G8A1 A0ACM8G8A1 LOC121838517 PTHR11214:SF411 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115331202|UniProtKB=A0ACM8EBV0 A0ACM8EBV0 LOC115331202 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120843794|UniProtKB=A0ACM8EWW2 A0ACM8EWW2 LOC120843794 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115332144|UniProtKB=A0ACM8EDB8 A0ACM8EDB8 ZnT86D PTHR45755:SF6 FAMILY NOT NAMED ZINC TRANSPORTER 7 monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;zinc ion transmembrane transport#GO:0071577;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 endomembrane system#GO:0012505;Golgi cisterna#GO:0031985;cytoplasm#GO:0005737;Golgi cis cisterna#GO:0000137;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;Golgi stack#GO:0005795;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115322473|UniProtKB=A0ACM8ESQ4 A0ACM8ESQ4 LOC115322473 PTHR24394:SF64 ZINC FINGER PROTEIN CENTROSOME-ASSOCIATED ZINC FINGER PROTEIN CP190 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115309859|UniProtKB=A0ACM8F0R5 A0ACM8F0R5 LOC115309859 PTHR10151:SF114 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE C27A7.3 hydrolase activity#GO:0016787;catalytic activity#GO:0003824 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115313521|UniProtKB=A0ACM8EW60 A0ACM8EW60 LOC115313521 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8032632|UniProtKB=A0ACM8EG49 A0ACM8EG49 LOC8032632 PTHR44229:SF4 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] CHAIN DEHYDROGENASE_REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02990)-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121836778|UniProtKB=A0ACM8G1F9 A0ACM8G1F9 LOC121836778 PTHR47526:SF4 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8044028|UniProtKB=A0ACM8E928 A0ACM8E928 LOC8044028 PTHR20938:SF0 INTEGRATOR COMPLEX SUBUNIT 4 INTEGRATOR COMPLEX SUBUNIT 4 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;catabolic process#GO:0009056;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA processing#GO:0016180;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;integrator complex#GO:0032039 IXOSC|EnsemblGenome=LOC8026910|UniProtKB=A0ACM8DII0 A0ACM8DII0 PTHR24067:SF261 UBIQUITIN-CONJUGATING ENZYME E2 NEDD8-CONJUGATING ENZYME UBC-12 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115325729|UniProtKB=A0ACM8E622 A0ACM8E622 LOC115325729 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8052557|UniProtKB=A0ACM8EB67 A0ACM8EB67 LOC8052557 PTHR19317:SF0 PRENYLATED RAB ACCEPTOR 1-RELATED PRENYLATED RAB ACCEPTOR PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121833058|UniProtKB=A0ACM8FJC3 A0ACM8FJC3 LOC121833058 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8032116|UniProtKB=A0ACM8E051 A0ACM8E051 PTHR19376:SF72 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC1 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;transcription by RNA polymerase III#GO:0006383;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;RNA polymerase III complex#GO:0005666;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115324664|UniProtKB=A0ACM8E517 A0ACM8E517 LOC115324664 PTHR13267:SF3 ZINC FINGER PROTEIN 277 ZINC FINGER PROTEIN 277 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115308526|UniProtKB=A0ACM8ERR0 A0ACM8ERR0 LOC115308526 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043604|UniProtKB=A0ACM8DGS4 A0ACM8DGS4 RpS8 PTHR10394:SF3 40S RIBOSOMAL PROTEIN S8 SMALL RIBOSOMAL SUBUNIT PROTEIN ES8 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120850312|UniProtKB=A0ACM8FN16 A0ACM8FN16 PTHR45712:SF36 AGAP008170-PA PODOCAN ISOFORM X1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121833046|UniProtKB=A0ACM8FHY9 A0ACM8FHY9 LOC121833046 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC120838169|UniProtKB=A0ACM8EJB1 A0ACM8EJB1 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838758|UniProtKB=A0ACM8EJW0 A0ACM8EJW0 LOC120838758 PTHR13943:SF77 HRAS-LIKE SUPPRESSOR - RELATED PHOSPHOLIPASE A AND ACYLTRANSFERASE 1-LIKE hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;transferase activity#GO:0016740 glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8036143|UniProtKB=A0ACM8E2F3 A0ACM8E2F3 LOC8036143 PTHR31158:SF1 DUAL OXIDASE 2 DUAL OXIDASE MATURATION FACTOR 2 membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidase#PC00175;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8051539|UniProtKB=A0ACM8DPW5 A0ACM8DPW5 LOC8051539 PTHR24171:SF8 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1 IXOSC|EnsemblGenome=LOC120846031|UniProtKB=A0ACM8F276 A0ACM8F276 LOC120846031 PTHR11475:SF146 OXIDASE/PEROXIDASE GH11385P oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601 metabolite interconversion enzyme#PC00262;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC8033923|UniProtKB=A0ACM8G8J3 A0ACM8G8J3 LOC8033923 PTHR15481:SF0 RIBONUCLEIC ACID BINDING PROTEIN S1 LD23870P-RELATED RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121835270|UniProtKB=A0ACM8FTM2 A0ACM8FTM2 LOC121835270 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840869|UniProtKB=A0ACM8FEQ0 A0ACM8FEQ0 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC121838220|UniProtKB=A0ACM8G8I3 A0ACM8G8I3 LOC121838220 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115321837|UniProtKB=A0ACM8E223 A0ACM8E223 Orc1 PTHR10763:SF23 CELL DIVISION CONTROL PROTEIN 6-RELATED ORIGIN RECOGNITION COMPLEX SUBUNIT 1 sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;binding#GO:0005488;DNA replication origin binding#GO:0003688;nucleic acid binding#GO:0003676 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;DNA replication#GO:0006260;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA replication initiation#GO:0006270;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;nuclear origin of replication recognition complex#GO:0005664 replication origin binding protein#PC00199 IXOSC|EnsemblGenome=LOC8028211|UniProtKB=A0ACM8FK95 A0ACM8FK95 LOC8028211 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 IXOSC|EnsemblGenome=LOC8023461|UniProtKB=A0ACM8DH60 A0ACM8DH60 LOC8023461 PTHR24114:SF50 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74A IXOSC|EnsemblGenome=LOC120847089|UniProtKB=A0ACM8F3M4 A0ACM8F3M4 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8024581|UniProtKB=A0ACM8DIG0 A0ACM8DIG0 LOC8024581 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8024511|UniProtKB=A0ACM8FCE2 A0ACM8FCE2 LOC8024511 PTHR14057:SF47 TRANSCRIPTION FACTOR ONECUT HOMEOBOX PROTEIN ONECUT sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121834112|UniProtKB=A0ACM8FQ62 A0ACM8FQ62 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849679|UniProtKB=A0ACM8F8I7 A0ACM8F8I7 LOC120849679 PTHR10083:SF390 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED PAPILIN endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115311253|UniProtKB=A0ACM8EF68 A0ACM8EF68 LOC115311253 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836605|UniProtKB=A0ACM8FZB3 A0ACM8FZB3 LOC121836605 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839509|UniProtKB=A0ACM8EN04 A0ACM8EN04 LOC120839509 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115332990|UniProtKB=A0ACM8EF79 A0ACM8EF79 LOC115332990 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115326772|UniProtKB=A0ACM8E6E7 A0ACM8E6E7 LOC115326772 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115316744|UniProtKB=A0ACM8ERB1 A0ACM8ERB1 LOC115316744 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312540|UniProtKB=A0ACM8DS79 A0ACM8DS79 LOC115312540 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;response to heat#GO:0009408;response to stress#GO:0006950;protein refolding#GO:0042026;protein metabolic process#GO:0019538;protein folding#GO:0006457;response to stimulus#GO:0050896;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC8027389|UniProtKB=A0ACM8DM86 A0ACM8DM86 LOC8027389 PTHR46693:SF1 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 15 IXOSC|EnsemblGenome=LOC120847649|UniProtKB=A0ACM8F4B0 A0ACM8F4B0 LOC120847649 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8051752|UniProtKB=A0ACM8DTN7 A0ACM8DTN7 ND-B16.6 PTHR12966:SF0 NADH DEHYDROGENASE UBIQUINONE 1 ALPHA SUBCOMPLEX SUBUNIT 13 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 13 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;membrane#GO:0016020;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115311573|UniProtKB=A0ACM8DR62 A0ACM8DR62 LOC115311573 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC115326041|UniProtKB=A0ACM8E5D2 A0ACM8E5D2 LOC115326041 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115320900|UniProtKB=A0ACM8FAH4 A0ACM8FAH4 LOC115320900 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321246|UniProtKB=A0ACM8E1M4 A0ACM8E1M4 LOC115321246 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120836326|UniProtKB=A0ACM8F2U1 A0ACM8F2U1 LOC120836326 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8044064|UniProtKB=A0ACM8DZA4 A0ACM8DZA4 POSH PTHR14167:SF51 SH3 DOMAIN-CONTAINING RING-TYPE E3 UBIQUITIN TRANSFERASE molecular adaptor activity#GO:0060090;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;protein-macromolecule adaptor activity#GO:0030674;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;positive regulation of JNK cascade#GO:0046330;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;positive regulation of MAPK cascade#GO:0043410;regulation of JNK cascade#GO:0046328 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121047718|UniProtKB=A0ACM8FGM3 A0ACM8FGM3 LOC121047718 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120846520|UniProtKB=A0ACM8F2K7 A0ACM8F2K7 LOC120846520 PTHR14209:SF19 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 hydrolase#PC00121;esterase#PC00097;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115328346|UniProtKB=A0ACM8EN62 A0ACM8EN62 LOC115328346 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC121835463|UniProtKB=A0ACM8FU83 A0ACM8FU83 LOC121835463 PTHR43977:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 IXOSC|EnsemblGenome=LOC120848258|UniProtKB=A0ACM8FHV0 A0ACM8FHV0 LOC120848258 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120841478|UniProtKB=A0ACM8ERB2 A0ACM8ERB2 LOC120841478 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023409|UniProtKB=A0ACM8DGY7 A0ACM8DGY7 LOC8023409 PTHR11306:SF0 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED LP08842P-RELATED lipid binding#GO:0008289;steroid binding#GO:0005496;sterol binding#GO:0032934;binding#GO:0005488 lipid transport#GO:0006869;macromolecule localization#GO:0033036;sterol transport#GO:0015918;establishment of localization#GO:0051234;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;transport#GO:0006810 IXOSC|EnsemblGenome=LOC8031831|UniProtKB=A0ACM8DQ76 A0ACM8DQ76 gbb PTHR11848:SF310 TGF-BETA FAMILY PROTEIN 60A-RELATED molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;cytokine activity#GO:0005125;signaling receptor regulator activity#GO:0030545 cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to growth factor stimulus#GO:0071363;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;signaling#GO:0023052;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;response to endogenous stimulus#GO:0009719 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 growth factor#PC00112 DPP-SCW signaling pathway#P06212>SCW full length#P06275;SCW signaling pathway#P06216>SCW#P06326;DPP-SCW signaling pathway#P06212>SCW#P06259;TGF-beta signaling pathway#P00052>TGFbeta#P01286;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;SCW signaling pathway#P06216>SCW full length#P06322;GBB signaling pathway#P06214>GBB#P06294;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256 IXOSC|EnsemblGenome=LOC8026657|UniProtKB=A0ACM8DS61 A0ACM8DS61 Eaat1 PTHR11958:SF63 SODIUM/DICARBOXYLATE SYMPORTER-RELATED AMINO ACID TRANSPORTER transmembrane transporter activity#GO:0022857;neutral L-amino acid transmembrane transporter activity#GO:0015175;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310;solute:monoatomic cation symporter activity#GO:0015294;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;sodium:dicarboxylate symporter activity#GO:0017153 L-glutamate import#GO:0051938;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;acidic amino acid transport#GO:0015800;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;transport#GO:0006810;establishment of localization#GO:0051234;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;L-glutamate transmembrane transport#GO:0015813;dicarboxylic acid transport#GO:0006835 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Ionotropic glutamate receptor pathway#P00037>EAAT#P01011;Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036 IXOSC|EnsemblGenome=LOC8026398|UniProtKB=A0ACM8DRX9 A0ACM8DRX9 crm PTHR21677:SF1 CRAMPED PROTEIN PROTEIN CRAMPED-LIKE binding#GO:0005488;chromatin binding#GO:0003682 developmental process#GO:0032502;pattern specification process#GO:0007389;multicellular organismal process#GO:0032501;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8025001|UniProtKB=A0ACM8DIW6 A0ACM8DIW6 LOC8025001 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8043598|UniProtKB=A0ACM8DGR2 A0ACM8DGR2 LOC8043598 PTHR46830:SF2 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220 IXOSC|EnsemblGenome=LOC115315951|UniProtKB=A0ACM8DVB7 A0ACM8DVB7 LOC115315951 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115317583|UniProtKB=A0ACM8FWA3 A0ACM8FWA3 LOC115317583 PTHR22930:SF289 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035585|UniProtKB=A0ACM8DNK0 A0ACM8DNK0 LOC8035585 PTHR11347:SF102 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE 3',5'-CYCLIC PHOSPHODIESTERASE PDE-2-RELATED phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;cyclic-nucleotide phosphodiesterase activity#GO:0004112;identical protein binding#GO:0042802;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;protein binding#GO:0005515;hydrolase activity#GO:0016787;binding#GO:0005488 small molecule metabolic process#GO:0044281;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;regulation of organelle organization#GO:0033043;purine-containing compound metabolic process#GO:0072521;negative regulation of biological process#GO:0048519;phosphorus metabolic process#GO:0006793;negative regulation of cell communication#GO:0010648;nucleotide metabolic process#GO:0009117;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;ribonucleotide metabolic process#GO:0009259;regulation of intracellular signal transduction#GO:1902531;negative regulation of signal transduction#GO:0009968;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;regulation of cellular process#GO:0050794;purine ribonucleotide catabolic process#GO:0009154;regulation of mitochondrion organization#GO:0010821;primary metabolic process#GO:0044238;positive regulation of biosynthetic process#GO:0009891;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;carbohydrate derivative metabolic process#GO:1901135;positive regulation of cellular process#GO:0048522;ribonucleotide catabolic process#GO:0009261;cGMP metabolic process#GO:0046068;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cyclic nucleotide metabolic process#GO:0009187;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;nucleotide catabolic process#GO:0009166 cytosol#GO:0005829;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;mitochondrial membrane#GO:0031966;nucleus#GO:0005634;mitochondrial envelope#GO:0005740;cell periphery#GO:0071944;plasma membrane region#GO:0098590;organelle outer membrane#GO:0031968;plasma membrane#GO:0005886;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle inner membrane#GO:0019866;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;synaptic membrane#GO:0097060;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle lumen#GO:0043233;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;outer membrane#GO:0019867 hydrolase#PC00121;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC115315485|UniProtKB=A0ACM8FSL1 A0ACM8FSL1 LOC115315485 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836021|UniProtKB=A0ACM8FWU0 A0ACM8FWU0 LOC121836021 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838315|UniProtKB=A0ACM8G8P2 A0ACM8G8P2 LOC121838315 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029786|UniProtKB=A0ACM8EVL1 A0ACM8EVL1 na PTHR46141:SF1 SODIUM LEAK CHANNEL NON-SELECTIVE PROTEIN SODIUM LEAK CHANNEL NALCN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 positive regulation of signaling#GO:0023056;positive regulation of synaptic transmission#GO:0050806;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133 IXOSC|EnsemblGenome=LOC120841472|UniProtKB=A0ACM8FFA3 A0ACM8FFA3 twf PTHR13759:SF10 TWINFILIN TWINFILIN protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin monomer binding#GO:0003785 cellular process#GO:0009987;actin filament depolymerization#GO:0030042;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of anatomical structure size#GO:0090066;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;cellular component disassembly#GO:0022411;regulation of actin filament organization#GO:0110053;actin polymerization or depolymerization#GO:0008154;negative regulation of protein depolymerization#GO:1901880;protein depolymerization#GO:0051261;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of cell projection organization#GO:0031344;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;regulation of plasma membrane bounded cell projection organization#GO:0120035;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cellular component organization#GO:0051129;negative regulation of organelle organization#GO:0010639;regulation of actin filament depolymerization#GO:0030834;protein-containing complex disassembly#GO:0032984;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;actin filament-based process#GO:0030029;actin filament capping#GO:0051693;negative regulation of protein polymerization#GO:0032272;regulation of cell projection assembly#GO:0060491;negative regulation of protein-containing complex assembly#GO:0031333;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494 cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;actin filament#GO:0005884;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC8042868|UniProtKB=A0ACM8DY36 A0ACM8DY36 LOC8042868 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8038221|UniProtKB=A0ACM8E7S3 A0ACM8E7S3 LOC8038221 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115318262|UniProtKB=A0ACM8EGZ9 A0ACM8EGZ9 LOC115318262 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121046100|UniProtKB=A0ACM8FBW1 A0ACM8FBW1 LOC121046100 PTHR33236:SF5 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034139|UniProtKB=A0ACM8DJ06 A0ACM8DJ06 Cog7 PTHR21443:SF0 CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 7 CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 7 protein localization to Golgi apparatus#GO:0034067;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;Golgi organization#GO:0007030;cellular component organization#GO:0016043;macromolecule localization#GO:0033036;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;protein localization to organelle#GO:0033365 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;COG complex#GO:0017119;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8042828|UniProtKB=A0ACM8EUD7 A0ACM8EUD7 LOC8042828 PTHR31649:SF1 AGAP009604-PA FARNESOIC ACID O-METHYL TRANSFERASE DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8038228|UniProtKB=A0ACM8FQS0 A0ACM8FQS0 LOC8038228 PTHR24289:SF24 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 21-HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 lipid metabolic process#GO:0006629;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;hormone biosynthetic process#GO:0042446;biosynthetic process#GO:0009058;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;hormone metabolic process#GO:0042445 IXOSC|EnsemblGenome=LOC115308654|UniProtKB=A0ACM8F0B1 A0ACM8F0B1 LOC115308654 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027440|UniProtKB=A0ACM8EDJ3 A0ACM8EDJ3 LOC8027440 PTHR11177:SF408 CHITINASE ACIDIC MAMMALIAN CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC121834471|UniProtKB=A0ACM8FQ39 A0ACM8FQ39 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8025910|UniProtKB=A0ACM8DUG2 A0ACM8DUG2 LOC8025910 PTHR11475:SF150 OXIDASE/PEROXIDASE LD42267P oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;peroxidase activity#GO:0004601;catalytic activity#GO:0003824 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121837689|UniProtKB=A0ACM8G4P1 A0ACM8G4P1 LOC121837689 PTHR13147:SF5 FOUR-JOINTED BOX PROTEIN 1 FOUR-JOINTED BOX PROTEIN 1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cell communication#GO:0007154;cell-cell signaling#GO:0007267;signaling#GO:0023052;biological regulation#GO:0065007;regulation of biological process#GO:0050789;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC115326770|UniProtKB=A0ACM8F514 A0ACM8F514 PTHR48575:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849023|UniProtKB=A0ACM8G4V3 A0ACM8G4V3 LOC120849023 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034119|UniProtKB=A0ACM8DIZ9 A0ACM8DIZ9 LOC8034119 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8041285|UniProtKB=A0ACM8EIX6 A0ACM8EIX6 LOC8041285 PTHR19957:SF411 SYNTAXIN LD23667P SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024 exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;synaptic vesicle#GO:0008021;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;synapse#GO:0045202;SNARE complex#GO:0031201;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737 SNARE protein#PC00034 Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Parkinson disease#P00049>Syntaxin#P01215 IXOSC|EnsemblGenome=LOC120837538|UniProtKB=A0ACM8EHL6 A0ACM8EHL6 LOC120837538 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120841332|UniProtKB=A0ACM8ERF6 A0ACM8ERF6 LOC120841332 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319845|UniProtKB=A0ACM8EMH1 A0ACM8EMH1 LOC115319845 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8031840|UniProtKB=A0ACM8DIU1 A0ACM8DIU1 LOC8031840 PTHR12514:SF1 ENHANCER OF YELLOW 2 TRANSCRIPTION FACTOR TRANSCRIPTION AND MRNA EXPORT FACTOR ENY2 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA transport#GO:0050658;RNA localization#GO:0006403;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;regulation of DNA-templated transcription#GO:0006355;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;regulation of RNA metabolic process#GO:0051252;nuclear export#GO:0051168;macromolecule localization#GO:0033036;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;nitrogen compound transport#GO:0071705;regulation of metabolic process#GO:0019222;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;gene expression#GO:0010467;metabolic process#GO:0008152 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;DUBm complex#GO:0071819;SAGA complex#GO:0000124;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transferase complex#GO:1990234;transcription export complex 2#GO:0070390;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SAGA-type complex#GO:0070461;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8035456|UniProtKB=A0ACM8E957 A0ACM8E957 LOC8035456 PTHR23048:SF60 MYOSIN LIGHT CHAIN 1, 3 CA2+ BINDING PROTEIN intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115320059|UniProtKB=A0ACM8FTF8 A0ACM8FTF8 LOC115320059 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121837370|UniProtKB=A0ACM8G4N9 A0ACM8G4N9 LOC121837370 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120837687|UniProtKB=A0ACM8FR63 A0ACM8FR63 LOC120837687 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8043865|UniProtKB=A0ACM8ER60 A0ACM8ER60 LOC8043865 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC120843804|UniProtKB=A0ACM8EWM8 A0ACM8EWM8 LOC120843804 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8030661|UniProtKB=A0ACM8DMR9 A0ACM8DMR9 RpL4 PTHR19431:SF0 60S RIBOSOMAL PROTEIN L4 LARGE RIBOSOMAL SUBUNIT PROTEIN UL4 binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8037101|UniProtKB=A0ACM8EK40 A0ACM8EK40 cin PTHR10192:SF33 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN GEPHYRIN transferase activity#GO:0016740;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;protein localization to membrane#GO:0072657;postsynapse organization#GO:0099173;cell junction organization#GO:0034330;synapse organization#GO:0050808;receptor clustering#GO:0043113;localization within membrane#GO:0051668;organophosphate biosynthetic process#GO:0090407;cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;macromolecule localization#GO:0033036;membrane organization#GO:0061024;biosynthetic process#GO:0009058;metabolic process#GO:0008152;intracellular protein localization#GO:0008104;neuromuscular junction development#GO:0007528;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;neuron projection#GO:0043005;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;dendritic tree#GO:0097447;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120844620|UniProtKB=A0ACM8FVP3 A0ACM8FVP3 LOC120844620 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8030643|UniProtKB=A0ACM8FS61 A0ACM8FS61 LOC8030643 PTHR14995:SF2 AMNIONLESS PROTEIN AMNIONLESS endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;multicellular organismal process#GO:0032501;cellular process#GO:0009987;renal system process#GO:0003014;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;establishment of localization#GO:0051234;import into cell#GO:0098657;renal absorption#GO:0070293;localization#GO:0051179;transport#GO:0006810 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;apical plasma membrane#GO:0016324;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;apical part of cell#GO:0045177;signaling receptor complex#GO:0043235 IXOSC|EnsemblGenome=LOC8052934|UniProtKB=A0ACM8E8B3 A0ACM8E8B3 LOC8052934 PTHR11085:SF9 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-1 transcription coregulator activity#GO:0003712;catalytic activity#GO:0003824;transcription corepressor activity#GO:0003714;histone deacetylase activity#GO:0004407;deacylase activity#GO:0160215;transferase activity#GO:0016740;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transcription regulator activity#GO:0140110;deacetylase activity#GO:0019213;histone modifying activity#GO:0140993 heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;cellular process#GO:0009987;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;constitutive heterochromatin formation#GO:0140719;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;cellular response to stress#GO:0033554;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;heterochromatin formation#GO:0031507;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 membraneless organelle#GO:0043228;heterochromatin#GO:0000792;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;nucleus#GO:0005634;organelle inner membrane#GO:0019866;chromatin#GO:0000785;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;nuclear envelope#GO:0005635;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;chromosome#GO:0005694;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 p53 pathway#P00059>SIRT-1#P04632 IXOSC|EnsemblGenome=LOC8035578|UniProtKB=A0ACM8DGM5 A0ACM8DGM5 LOC8035578 PTHR32170:SF3 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 PROTEASOME ACTIVATOR COMPLEX SUBUNIT 4 enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8053755|UniProtKB=A0ACM8E3R9 A0ACM8E3R9 LOC8053755 PTHR10828:SF17 M-PHASE INDUCER PHOSPHATASE DUAL SPECIFICITY PHOSPHATASE CDC25 CDC25-LIKE PROTEIN PHOSPHATASE TWINE-RELATED catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell cycle G2/M phase transition#GO:0044839;regulation of reproductive process#GO:2000241;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;mitotic cell cycle phase transition#GO:0044772;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cell cycle process#GO:0022402;regulation of meiotic cell cycle#GO:0051445;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8050740|UniProtKB=A0ACM8E3D8 A0ACM8E3D8 DUBAI PTHR24006:SF908 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE DEUBIQUITINATING APOPTOTIC INHIBITOR, ISOFORM A deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;cysteine-type deubiquitinase activity#GO:0004843;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC121835174|UniProtKB=A0ACM8FSR0 A0ACM8FSR0 LOC121835174 PTHR12231:SF278 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN KAPPA, ISOFORM A protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;synapse organization#GO:0050808 membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;cell junction#GO:0030054 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121046045|UniProtKB=A0ACM8FD19 A0ACM8FD19 LOC121046045 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120837825|UniProtKB=A0ACM8FJI9 A0ACM8FJI9 LOC120837825 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120837876|UniProtKB=A0ACM8EI09 A0ACM8EI09 LOC120837876 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029197|UniProtKB=A0ACM8G5E5 A0ACM8G5E5 LOC8029197 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121833207|UniProtKB=A0ACM8FJZ3 A0ACM8FJZ3 LOC121833207 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043558|UniProtKB=A0ACM8E2A8 A0ACM8E2A8 LOC8043558 PTHR11904:SF9 METHYLTHIOADENOSINE/PURINE NUCLEOSIDE PHOSPHORYLASE PURINE NUCLEOSIDE PHOSPHORYLASE-RELATED glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;pentosyltransferase activity#GO:0016763 purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule catabolic process#GO:0034656;phosphorus metabolic process#GO:0006793;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;nucleoside catabolic process#GO:0009164;nucleotide metabolic process#GO:0009117;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleoside catabolic process#GO:0006152;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;nucleoside metabolic process#GO:0009116;pyridine-containing compound metabolic process#GO:0072524;purine nucleoside metabolic process#GO:0042278;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;glycosyl compound catabolic process#GO:1901658;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate biosynthetic process#GO:1901293 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 nucleotide kinase#PC00172;kinase#PC00137 Adenine and hypoxanthine salvage pathway#P02723>Inosine phosphorylase#P02813;Xanthine and guanine salvage pathway#P02788>Deoxyguanosine phosphorylase#P03248;Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine phosphorylase#P02808;Adenine and hypoxanthine salvage pathway#P02723>Deoxyinosine phosphorylase#P02812;Adenine and hypoxanthine salvage pathway#P02723>Adenine phosphorylase#P02805;Xanthine and guanine salvage pathway#P02788>Guanosine phosphorylase#P03250 IXOSC|EnsemblGenome=LOC115321597|UniProtKB=A0ACM8F3H9 A0ACM8F3H9 LOC115321597 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115326952|UniProtKB=A0ACM8E6H7 A0ACM8E6H7 LOC115326952 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252 nucleobase-containing compound metabolic process#GO:0006139;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC121836236|UniProtKB=A0ACM8FXI0 A0ACM8FXI0 LOC121836236 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115330856|UniProtKB=A0ACM8EBW3 A0ACM8EBW3 LOC115330856 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320171|UniProtKB=A0ACM8E0R3 A0ACM8E0R3 RpS3 PTHR11760:SF76 30S/40S RIBOSOMAL PROTEIN S3 SMALL RIBOSOMAL SUBUNIT PROTEIN US3 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 positive regulation of apoptotic process#GO:0043065;regulation of apoptotic process#GO:0042981;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of signaling#GO:0023056;regulation of apoptotic signaling pathway#GO:2001233;regulation of signaling#GO:0023051;positive regulation of apoptotic signaling pathway#GO:2001235;regulation of cell communication#GO:0010646;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;regulation of programmed cell death#GO:0043067 ribosome#GO:0005840;cytosolic ribosome#GO:0022626;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8023334|UniProtKB=A0ACM8DGU6 A0ACM8DGU6 PTHR45748:SF7 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phosphorus metabolic process#GO:0006793;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;vacuole organization#GO:0007033;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637;cellular component organization or biogenesis#GO:0071840;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505 transferase#PC00220;kinase#PC00137 IXOSC|EnsemblGenome=LOC8034579|UniProtKB=A0ACM8E9Z3 A0ACM8E9Z3 Pi3K59F PTHR10048:SF7 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 catabolic process#GO:0009056;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;localization#GO:0051179;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;vacuole organization#GO:0007033;intracellular signal transduction#GO:0035556;organelle assembly#GO:0070925;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macroautophagy#GO:0016236;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;pexophagy#GO:0000425;establishment of localization#GO:0051234;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;transport#GO:0006810;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;endocytosis#GO:0006897;signaling#GO:0023052;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;process utilizing autophagic mechanism#GO:0061919;phosphatidylinositol phosphate biosynthetic process#GO:0046854;cellular component assembly#GO:0022607;glycerophospholipid metabolic process#GO:0006650;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;autophagy#GO:0006914;signal transduction#GO:0007165;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;autophagosome assembly#GO:0000045;metabolic process#GO:0008152 membrane#GO:0016020;microbody#GO:0042579;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;transferase complex#GO:1990234;phagophore assembly site#GO:0000407;extrinsic component of membrane#GO:0019898;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;peroxisome#GO:0005777;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;phosphatidylinositol 3-kinase complex, class III#GO:0035032;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 kinase#PC00137 p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Angiogenesis#P00005>PI3K#P00236;PDGF signaling pathway#P00047>PI3K#P01168;Ras Pathway#P04393>PI3K#P04567;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;EGF receptor signaling pathway#P00018>PI3K#P00557;FGF signaling pathway#P00021>PI3K#P00640;p53 pathway feedback loops 2#P04398>PI3K#P04661;T cell activation#P00053>PI3K#P01322;VEGF signaling pathway#P00056>PI3K#P01413;Integrin signalling pathway#P00034>PI3K#P00936 IXOSC|EnsemblGenome=LOC8053985|UniProtKB=A0ACM8DZ02 A0ACM8DZ02 LOC8053985 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115323032|UniProtKB=A0ACM8EG78 A0ACM8EG78 LOC115323032 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8027153|UniProtKB=A0ACM8DT50 A0ACM8DT50 LOC8027153 PTHR18945:SF927 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT BETA-LIKE 2 establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;calcium ion transport#GO:0006816;transport#GO:0006810;synaptic transmission, cholinergic#GO:0007271;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;monoatomic ion transmembrane transport#GO:0034220;synaptic signaling#GO:0099536;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088 IXOSC|EnsemblGenome=LOC120841625|UniProtKB=A0ACM8ES26 A0ACM8ES26 LOC120841625 PTHR11227:SF29 WD-REPEAT PROTEIN INTERACTING WITH PHOSPHOINOSIDES WIPI -RELATED WD REPEAT DOMAIN PHOSPHOINOSITIDE-INTERACTING PROTEIN 4 phosphatidylinositol-3-phosphate binding#GO:0032266;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;molecular adaptor activity#GO:0060090;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;protein-macromolecule adaptor activity#GO:0030674;ion binding#GO:0043167 process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;polysaccharide catabolic process#GO:0000272;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component assembly#GO:0022607;organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033;localization#GO:0051179;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;pexophagy#GO:0000425;energy derivation by oxidation of organic compounds#GO:0015980;glycogen catabolic process#GO:0005980;macromolecule localization#GO:0033036;macroautophagy#GO:0016236 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;phagophore assembly site#GO:0000407;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120850512|UniProtKB=A0ACM8FA11 A0ACM8FA11 LOC120850512 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120849798|UniProtKB=A0ACM8F8S2 A0ACM8F8S2 LOC120849798 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031017|UniProtKB=A0ACM8DZ74 A0ACM8DZ74 Rab10 PTHR47980:SF23 LD44762P SMALL MONOMERIC GTPASE localization within membrane#GO:0051668;cellular localization#GO:0051641;secretion#GO:0046903;localization#GO:0051179;secretion by cell#GO:0032940;endocytic recycling#GO:0032456;export from cell#GO:0140352;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;membrane#GO:0016020;secretory vesicle#GO:0099503;endomembrane system#GO:0012505;cytoplasm#GO:0005737 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;TGF-beta signaling pathway#P00052>Ras-GDP#P01291 IXOSC|EnsemblGenome=LOC8033202|UniProtKB=A0ACM8EAS0 A0ACM8EAS0 LOC8033202 PTHR47634:SF26 PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED SERINE-ARGININE PROTEIN KINASE AT 79D-RELATED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;RNA splicing, via transesterification reactions#GO:0000375;regulation of RNA metabolic process#GO:0051252;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;RNA metabolic process#GO:0016070;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115325016|UniProtKB=A0ACM8E5V0 A0ACM8E5V0 LOC115325016 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833516|UniProtKB=A0ACM8FLE9 A0ACM8FLE9 LOC121833516 PTHR10537:SF3 DNA PRIMASE LARGE SUBUNIT DNA PRIMASE LARGE SUBUNIT DNA replication initiation#GO:0006270;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;DNA-templated DNA replication#GO:0006261;RNA metabolic process#GO:0016070;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774 transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-DNA complex#GO:0032993;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 primase#PC00189 DNA replication#P00017>Primase#P00528 IXOSC|EnsemblGenome=LOC115331690|UniProtKB=A0ACM8G1M5 A0ACM8G1M5 LOC115331690 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311441|UniProtKB=A0ACM8DQT3 A0ACM8DQT3 LOC115311441 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034854|UniProtKB=A0ACM8E0B5 A0ACM8E0B5 LOC8034854 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121838058|UniProtKB=A0ACM8G6F3 A0ACM8G6F3 LOC121838058 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8028251|UniProtKB=A0ACM8FKA5 A0ACM8FKA5 MED18 PTHR13321:SF2 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 18 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 18 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription initiation#GO:2000142 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8040686|UniProtKB=A0ACM8E532 A0ACM8E532 LOC8040686 PTHR14949:SF54 EGF-LIKE-DOMAIN, MULTIPLE 7, 8 PROTEIN SHIFTED signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120841166|UniProtKB=A0ACM8EQZ2 A0ACM8EQZ2 LOC120841166 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120845268|UniProtKB=A0ACM8F087 A0ACM8F087 LOC120845268 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8037302|UniProtKB=A0ACM8DK30 A0ACM8DK30 LOC8037302 PTHR23349:SF63 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST FER3-LIKE PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC121047066|UniProtKB=A0ACM8FE54 A0ACM8FE54 LOC121047066 PTHR47217:SF1 GLOBIN-LIKE PROTEIN GLOBIN-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115324999|UniProtKB=A0ACM8FA43 A0ACM8FA43 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834248|UniProtKB=A0ACM8FQK0 A0ACM8FQK0 PTHR12176:SF78 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE lysine N-methyltransferase activity#GO:0016278;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835340|UniProtKB=A0ACM8FU53 A0ACM8FU53 LOC121835340 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8040463|UniProtKB=A0ACM8EZY2 A0ACM8EZY2 LOC8040463 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8023609|UniProtKB=A0ACM8DU96 A0ACM8DU96 LOC8023609 PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 binding#GO:0005488;protein binding#GO:0005515 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8032103|UniProtKB=A0ACM8DMV1 A0ACM8DMV1 LOC8032103 PTHR17271:SF1 PLECKSTRIN HOMOLOGY PH DOMAIN-CONTAINING PROTEIN PROTEIN OUTSPREAD protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779 intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8040195|UniProtKB=A0ACM8E3T6 A0ACM8E3T6 LOC8040195 PTHR24068:SF567 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 IXOSC|EnsemblGenome=LOC8038887|UniProtKB=A0ACM8E387 A0ACM8E387 LOC8038887 PTHR22891:SF198 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;single-stranded RNA binding#GO:0003727;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519 cytoplasmic ribonucleoprotein granule#GO:0036464;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC121832983|UniProtKB=A0ACM8FRW1 A0ACM8FRW1 LOC8029105 PTHR12027:SF72 WNT RELATED PROTEIN WNT-6 G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell fate commitment#GO:0045165;system development#GO:0048731;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 IXOSC|EnsemblGenome=LOC8032234|UniProtKB=A0ACM8DVS0 A0ACM8DVS0 LOC8032234 PTHR10846:SF77 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 4-RELATED monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;antiporter activity#GO:0015297;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic cation channel activity#GO:0005261;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8043059|UniProtKB=A0ACM8FHQ8 A0ACM8FHQ8 LOC8043059 PTHR11469:SF1 GLUCOSE-6-PHOSPHATE ISOMERASE GLUCOSE-6-PHOSPHATE ISOMERASE small molecule binding#GO:0036094;binding#GO:0005488;carbohydrate binding#GO:0030246;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;monosaccharide binding#GO:0048029;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861 carbohydrate biosynthetic process#GO:0016051;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;ADP catabolic process#GO:0046032;pyruvate metabolic process#GO:0006090;monocarboxylic acid metabolic process#GO:0032787;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;monosaccharide biosynthetic process#GO:0046364;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;ADP metabolic process#GO:0046031;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;aerobic respiration#GO:0009060;purine ribonucleoside diphosphate catabolic process#GO:0009181;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;nicotinamide nucleotide metabolic process#GO:0046496;gluconeogenesis#GO:0006094;ATP metabolic process#GO:0046034;purine-containing compound catabolic process#GO:0072523;glucose metabolic process#GO:0006006;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;oxoacid metabolic process#GO:0043436;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;energy derivation by oxidation of organic compounds#GO:0015980;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;glucose 6-phosphate metabolic process#GO:0051156;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;purine nucleotide catabolic process#GO:0006195 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;isomerase#PC00135 Pentose phosphate pathway#P02762>Glucose-P-Isomerase#P03080;Glycolysis#P00024>Phosphoglucose isomerase#P00674 IXOSC|EnsemblGenome=LOC120836934|UniProtKB=A0ACM8EH33 A0ACM8EH33 LOC120836934 PTHR24067:SF384 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN CONJUGATING ENZYME E2 M cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120849057|UniProtKB=A0ACM8F7V4 A0ACM8F7V4 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025373|UniProtKB=A0ACM8FUD3 A0ACM8FUD3 LOC8025373 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE response to stress#GO:0006950;response to heat#GO:0009408;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;response to stimulus#GO:0050896;protein folding#GO:0006457;protein metabolic process#GO:0019538;protein refolding#GO:0042026 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC121048457|UniProtKB=A0ACM8G754 A0ACM8G754 LOC121048457 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120836573|UniProtKB=A0ACM8EFY5 A0ACM8EFY5 LOC120836573 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120846572|UniProtKB=A0ACM8F2P3 A0ACM8F2P3 LOC120846572 PTHR10907:SF47 REGUCALCIN REGUCALCIN hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of calcium-mediated signaling#GO:0050848;regulation of signal transduction#GO:0009966;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;esterase#PC00097 IXOSC|EnsemblGenome=LOC8027567|UniProtKB=A0ACM8G2M1 A0ACM8G2M1 LOC8027567 PTHR23291:SF112 BAX INHIBITOR-RELATED GROWTH HORMONE-INDUCIBLE TRANSMEMBRANE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;monoatomic ion transmembrane transport#GO:0034220;organelle organization#GO:0006996;mitochondrial calcium ion transmembrane transport#GO:0006851;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;release of sequestered calcium ion into cytosol#GO:0051209;cellular process#GO:0009987 endomembrane system#GO:0012505;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8034286|UniProtKB=A0ACM8ESP2 A0ACM8ESP2 LOC8034286 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC120836313|UniProtKB=A0ACM8ERN9 A0ACM8ERN9 LOC120836313 PTHR31893:SF5 TRANSMEMBRANE PROTEIN 151 HOMOLOG TRANSMEMBRANE PROTEIN 151 HOMOLOG membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120837368|UniProtKB=A0ACM8EGR0 A0ACM8EGR0 LOC120837368 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC121045501|UniProtKB=A0ACM8FC64 A0ACM8FC64 LOC121045501 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121045736|UniProtKB=A0ACM8FBY7 A0ACM8FBY7 LOC121045736 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC121837441|UniProtKB=A0ACM8G387 A0ACM8G387 LOC121837441 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042854|UniProtKB=A0ACM8F487 A0ACM8F487 LOC8042854 PTHR12274:SF3 GRANULIN GRANULIN PRECURSOR cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC121837852|UniProtKB=A0ACM8G524 A0ACM8G524 LOC121837852 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043620|UniProtKB=A0ACM8DGS1 A0ACM8DGS1 ND-B12 PTHR15082:SF2 NADH-UBIQUINONE OXIDOREDUCTASE B12 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 3 metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, NADH to ubiquinone#GO:0006120;ATP synthesis coupled electron transport#GO:0042773;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8036876|UniProtKB=A0ACM8DJZ1 A0ACM8DJZ1 LOC8036876 PTHR12687:SF4 NUCLEOLAR COMPLEX 2 AND RAD4-RELATED NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;intracellular organelle#GO:0043229;preribosome, large subunit precursor#GO:0030687;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;90S preribosome#GO:0030686;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC120836709|UniProtKB=A0ACM8EG82 A0ACM8EG82 LOC120836709 PTHR11214:SF407 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115317761|UniProtKB=A0ACM8DXB6 A0ACM8DXB6 LOC115317761 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 transporter#PC00227 IXOSC|EnsemblGenome=LOC8052544|UniProtKB=A0ACM8DLK5 A0ACM8DLK5 LOC8052544 PTHR11929:SF249 ALPHA- 1,3 -FUCOSYLTRANSFERASE FUCOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120846064|UniProtKB=A0ACM8F166 A0ACM8F166 LOC120846064 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC121834527|UniProtKB=A0ACM8FNX9 A0ACM8FNX9 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115311147|UniProtKB=A0ACM8F2R1 A0ACM8F2R1 LOC115311147 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC8053630|UniProtKB=A0ACM8DX08 A0ACM8DX08 LOC8053630 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC115329925|UniProtKB=A0ACM8FCQ8 A0ACM8FCQ8 LOC115329925 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115326361|UniProtKB=A0ACM8E795 A0ACM8E795 LOC115326361 PTHR11105:SF0 CITRATE LYASE SUBUNIT BETA-RELATED CITRAMALYL-COA LYASE, MITOCHONDRIAL lyase activity#GO:0016829;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 lyase#PC00144 Pyruvate metabolism#P02772>Citrate Lyase#P03137 IXOSC|EnsemblGenome=LOC8041694|UniProtKB=A0ACM8FX12 A0ACM8FX12 LOC8041694 PTHR12308:SF84 ANOCTAMIN ANOCTAMIN lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;intramembrane lipid carrier activity#GO:0140303 transport#GO:0006810;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule localization#GO:0033036;phospholipid transport#GO:0015914;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;biological regulation#GO:0065007;lipid transport#GO:0006869;lipid localization#GO:0010876;regulation of biological quality#GO:0065008;localization#GO:0051179;cellular component organization#GO:0016043;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8026789|UniProtKB=A0ACM8E3Y0 A0ACM8E3Y0 LOC8026789 PTHR16950:SF25 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER SLC39A7 transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324 metal ion transport#GO:0030001;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8029115|UniProtKB=A0ACM8ECV4 A0ACM8ECV4 Phf5a PTHR13120:SF0 PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A PHD FINGER-LIKE DOMAIN-CONTAINING PROTEIN 5A nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525 IXOSC|EnsemblGenome=LOC8023526|UniProtKB=A0ACM8DH83 A0ACM8DH83 DCP2 PTHR23114:SF17 M7GPPPN-MRNA HYDROLASE M7GPPPN-MRNA HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462 positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of mRNA metabolic process#GO:1903311;mRNA destabilization#GO:0061157;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;RNA catabolic process#GO:0006401;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 IXOSC|EnsemblGenome=LOC115311763|UniProtKB=A0ACM8FFU5 A0ACM8FFU5 LOC115311763 PTHR11361:SF20 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER MUTS PROTEIN HOMOLOG 5 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 reproductive process#GO:0022414;homologous recombination#GO:0035825;reciprocal homologous recombination#GO:0140527;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;nucleobase-containing compound metabolic process#GO:0006139;chromosome organization#GO:0051276;meiotic chromosome segregation#GO:0045132;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;nuclear chromosome segregation#GO:0098813;meiosis I#GO:0007127;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;homologous chromosome pairing at meiosis#GO:0007129;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;homologous chromosome segregation#GO:0045143;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8037699|UniProtKB=A0ACM8F3S0 A0ACM8F3S0 LOC8037699 PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell cycle#GO:0007049;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8029565|UniProtKB=A0ACM8E2H2 A0ACM8E2H2 LOC8029565 PTHR12226:SF5 MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 LEC35 -RELATED MANNOSE-P-DOLICHOL UTILIZATION DEFECT 1 PROTEIN cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate biosynthetic process#GO:0016051;biosynthetic process#GO:0009058;carbohydrate metabolic process#GO:0005975;metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;oligosaccharide biosynthetic process#GO:0009312 IXOSC|EnsemblGenome=LOC8042232|UniProtKB=A0ACM8EAA7 A0ACM8EAA7 LOC8042232 PTHR13966:SF5 ENDONUCLEASE RELATED ENDONUCLEASE G, MITOCHONDRIAL RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on DNA#GO:0140097;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520 apoptotic DNA fragmentation#GO:0006309;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;nucleic acid metabolic process#GO:0090304;execution phase of apoptosis#GO:0097194;cell death#GO:0008219;apoptotic process#GO:0006915;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;mitochondrial membrane#GO:0031966;organelle membrane#GO:0031090 Apoptosis signaling pathway#P00006>endoG#P00279 IXOSC|EnsemblGenome=LOC8039259|UniProtKB=A0ACM8FR56 A0ACM8FR56 LOC8039259 PTHR10404:SF84 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120844866|UniProtKB=A0ACM8F000 A0ACM8F000 LOC120844866 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121836164|UniProtKB=A0ACM8FXR0 A0ACM8FXR0 LOC121836164 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8034903|UniProtKB=A0ACM8E4G5 A0ACM8E4G5 LOC8034903 PTHR45682:SF22 AGAP008228-PA DUAL SPECIFICITY PROTEIN PHOSPHATASE hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8040514|UniProtKB=A0ACM8FRH4 A0ACM8FRH4 LOC8040514 PTHR33236:SF13 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308520|UniProtKB=A0ACM8EYF0 A0ACM8EYF0 LOC115308520 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115316872|UniProtKB=A0ACM8EQY1 A0ACM8EQY1 LOC115316872 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8029245|UniProtKB=A0ACM8DHV9 A0ACM8DHV9 LOC8029245 PTHR12289:SF38 METAXIN RELATED METAXIN-2 establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;establishment of localization in cell#GO:0051649;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585 mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;mitochondrial protein-containing complex#GO:0098798;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 transporter#PC00227 IXOSC|EnsemblGenome=LOC8051559|UniProtKB=A0ACM8G5D1 A0ACM8G5D1 LOC8051559 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115322622|UniProtKB=A0ACM8FYB4 A0ACM8FYB4 LOC115322622 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8032601|UniProtKB=A0ACM8DR69 A0ACM8DR69 LOC8032601 PTHR16356:SF1 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 TMCO6 TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 6 IXOSC|EnsemblGenome=LOC120837790|UniProtKB=A0ACM8EJ05 A0ACM8EJ05 CkIIbeta PTHR11740:SF0 CASEIN KINASE II SUBUNIT BETA CASEIN KINASE II SUBUNIT BETA-RELATED protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;serine/threonine protein kinase complex#GO:1902554;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095;kinase modulator#PC00140 Parkinson disease#P00049>Casein kinase II#P01236;Wnt signaling pathway#P00057>Casein Kinase 2#P01459;Cadherin signaling pathway#P00012>Casein kinase II#P00462 IXOSC|EnsemblGenome=LOC8043774|UniProtKB=A0ACM8DGY4 A0ACM8DGY4 LOC8043774 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8033383|UniProtKB=A0ACM8FRS6 A0ACM8FRS6 Trmt61 PTHR12133:SF2 TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE CATALYTIC SUBUNIT TRMT61A RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 catalytic complex#GO:1902494;transferase complex#GO:1990234;methyltransferase complex#GO:0034708;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8036180|UniProtKB=A0ACM8DVX4 A0ACM8DVX4 LOC8036180 PTHR12694:SF8 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;transcription coregulator activity#GO:0003712;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 transcription factor TFIID complex#GO:0005669;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 IXOSC|EnsemblGenome=LOC115317762|UniProtKB=A0ACM8F136 A0ACM8F136 LOC115317762 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8033077|UniProtKB=A0ACM8EMQ0 A0ACM8EMQ0 LOC8033077 PTHR23282:SF153 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. MAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844901|UniProtKB=A0ACM8F032 A0ACM8F032 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8036196|UniProtKB=A0ACM8EAN6 A0ACM8EAN6 LOC8036196 PTHR43674:SF17 NITRILASE C965.09-RELATED BETA-UREIDOPROPIONASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Pyrimidine Metabolism#P02771>Beta-Ureidopropionase#P03127 IXOSC|EnsemblGenome=LOC115316531|UniProtKB=A0ACM8DWN6 A0ACM8DWN6 PTHR46295:SF1 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 ENDOPLASMIC RETICULUM RESIDENT PROTEIN 44 catalytic activity, acting on a protein#GO:0140096;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;protein disulfide isomerase activity#GO:0003756 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC120838277|UniProtKB=A0ACM8EKG5 A0ACM8EKG5 LOC120838277 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043167|UniProtKB=A0ACM8EDR2 A0ACM8EDR2 LOC8043167 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120849660|UniProtKB=A0ACM8F845 A0ACM8F845 LOC120849660 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;steroid metabolic process#GO:0008202;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8039222|UniProtKB=A0ACM8DTB7 A0ACM8DTB7 LOC8039222 PTHR15407:SF28 FUKUTIN-RELATED MANNOSYLTRANSFERASE REGULATOR 14-RELATED carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 IXOSC|EnsemblGenome=LOC115328677|UniProtKB=A0ACM8E8L1 A0ACM8E8L1 LOC115328677 PTHR13318:SF292 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6, ISOFORM A-RELATED primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 IXOSC|EnsemblGenome=LOC8052387|UniProtKB=A0ACM8EPA8 A0ACM8EPA8 LOC8052387 PTHR36694:SF14 PASIFLORA 1, ISOFORM A-RELATED LP21121P IXOSC|EnsemblGenome=LOC115318953|UniProtKB=A0ACM8EUV5 A0ACM8EUV5 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120849335|UniProtKB=A0ACM8F8J5 A0ACM8F8J5 LOC120849335 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8042785|UniProtKB=A0ACM8DKZ2 A0ACM8DKZ2 Sem1 PTHR16771:SF0 26 PROTEASOME COMPLEX SUBUNIT DSS1 26S PROTEASOME COMPLEX SUBUNIT SEM1 metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896 proteasome complex#GO:0000502;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;peptidase complex#GO:1905368 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8024244|UniProtKB=A0ACM8FU50 A0ACM8FU50 LOC8024244 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 hydrolase#PC00121;galactosidase#PC00104 IXOSC|EnsemblGenome=LOC120850243|UniProtKB=A0ACM8F8D6 A0ACM8F8D6 LOC120850243 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8041646|UniProtKB=A0ACM8EB34 A0ACM8EB34 LOC8041646 PTHR46098:SF1 TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;tRNA methyltransferase activity#GO:0008175;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a tRNA#GO:0140101 gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8035777|UniProtKB=A0ACM8DP41 A0ACM8DP41 LOC8035777 PTHR11485:SF29 TRANSFERRIN TRANSFERRIN 2 iron ion transport#GO:0006826;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001 recycling endosome#GO:0055037;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;endosome#GO:0005768;extracellular region#GO:0005576;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115324885|UniProtKB=A0ACM8E4D1 A0ACM8E4D1 LOC115324885 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120839407|UniProtKB=A0ACM8ELR0 A0ACM8ELR0 LOC120839407 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8025174|UniProtKB=A0ACM8DQ93 A0ACM8DQ93 LOC8025174 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8035853|UniProtKB=A0ACM8DXF6 A0ACM8DXF6 LOC8035853 PTHR13102:SF0 NUCLEOLAR PROTEIN 9 NUCLEOLAR PROTEIN 9 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;ribosome localization#GO:0033750;organelle localization#GO:0051640;rRNA processing#GO:0006364;nuclear export#GO:0051168;nuclear transport#GO:0051169;localization#GO:0051179;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;transport#GO:0006810;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;intracellular transport#GO:0046907;rRNA metabolic process#GO:0016072;ribosomal subunit export from nucleus#GO:0000054;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;cellular localization#GO:0051641;RNA metabolic process#GO:0016070;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA#GO:0000460;establishment of organelle localization#GO:0051656;ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;establishment of localization in cell#GO:0051649;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120841832|UniProtKB=A0ACM8ESL7 A0ACM8ESL7 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115309979|UniProtKB=A0ACM8G8C3 A0ACM8G8C3 LOC115309979 PTHR10877:SF150 POLYCYSTIN FAMILY MEMBER LOCATION OF VULVA DEFECTIVE 1 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium channel activity#GO:0005262;calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 detection of mechanical stimulus#GO:0050982;response to abiotic stimulus#GO:0009628;detection of stimulus#GO:0051606;response to mechanical stimulus#GO:0009612;response to stimulus#GO:0050896;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ion channel#PC00133 IXOSC|EnsemblGenome=LOC8035610|UniProtKB=A0ACM8E6H4 A0ACM8E6H4 LOC8035610 PTHR25462:SF296 BONUS, ISOFORM C-RELATED RING-TYPE DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8051032|UniProtKB=A0ACM8DLH2 A0ACM8DLH2 LOC8051032 PTHR19300:SF30 BETA-1,4-GALACTOSYLTRANSFERASE BETA-1,4-GALACTOSYLTRANSFERASE 7 galactosyltransferase activity#GO:0008378;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 Wnt signaling pathway#P00057>Calcineurin#P01446 IXOSC|EnsemblGenome=LOC8052262|UniProtKB=A0ACM8DM22 A0ACM8DM22 ppan PTHR12661:SF5 PETER PAN-RELATED SUPPRESSOR OF SWI4 1 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991;preribosome, large subunit precursor#GO:0030687 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8033610|UniProtKB=A0ACM8DXE1 A0ACM8DXE1 PIP4K PTHR23086:SF150 PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE PHOSPHATIDYLINOSITOL 5-PHOSPHATE 4-KINASE, ISOFORM A phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phosphatidylinositol phosphate biosynthetic process#GO:0046854;organophosphate biosynthetic process#GO:0090407;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 kinase#PC00137;transferase#PC00220 IXOSC|EnsemblGenome=LOC121832862|UniProtKB=A0ACM8G849 A0ACM8G849 LOC121832862 PTHR15555:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 2 PROTEIN FON -RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 2 IXOSC|EnsemblGenome=LOC121832963|UniProtKB=A0ACM8FW59 A0ACM8FW59 LOC121832963 PTHR24257:SF17 CHYMOTRYPSIN-LIKE ELASTASE FAMILY MEMBER SUBFAMILY NOT NAMED serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8033735|UniProtKB=A0ACM8EDG7 A0ACM8EDG7 PTHR23399:SF2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 chromatin-protein adaptor activity#GO:0140463;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8033908|UniProtKB=A0ACM8FCD1 A0ACM8FCD1 Fkbp12 PTHR10516:SF466 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP12 catalytic activity, acting on a protein#GO:0140096;cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;regulation of transmembrane transport#GO:0034762;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;regulation of heart contraction#GO:0008016;protein metabolic process#GO:0019538;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;macromolecule biosynthetic process#GO:0009059;regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of calcium ion transport#GO:0051924;regulation of system process#GO:0044057;regulation of monoatomic cation transmembrane transport#GO:1904062;macromolecule metabolic process#GO:0043170;calcium-mediated signaling#GO:0019722;regulation of muscle system process#GO:0090257;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;protein folding#GO:0006457;signaling#GO:0023052;regulation of muscle contraction#GO:0006937;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;signal transduction#GO:0007165;protein maturation#GO:0051604;gene expression#GO:0010467;regulation of multicellular organismal process#GO:0051239;intracellular signaling cassette#GO:0141124;metabolic process#GO:0008152;regulation of release of sequestered calcium ion into cytosol#GO:0051279;regulation of localization#GO:0032879;regulation of transport#GO:0051049 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 IXOSC|EnsemblGenome=LOC120848036|UniProtKB=A0ACM8F479 A0ACM8F479 LOC120848036 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120838063|UniProtKB=A0ACM8EJR6 A0ACM8EJR6 LOC120838063 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293 transport#GO:0006810;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115332184|UniProtKB=A0ACM8ECY9 A0ACM8ECY9 LOC115332184 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8039068|UniProtKB=A0ACM8E9F1 A0ACM8E9F1 LOC8039068 PTHR13309:SF0 NUCLEAR FRAGILE X MENTAL RETARDATION PROTEIN INTERACTING PROTEIN 1 FMR1-INTERACTING PROTEIN NUFIP1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular component assembly#GO:0022607;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;protein-RNA complex organization#GO:0071826;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8025304|UniProtKB=A0ACM8DJ59 A0ACM8DJ59 LOC8025304 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115320391|UniProtKB=A0ACM8EIT8 A0ACM8EIT8 LOC115320391 PTHR12892:SF11 FGF RECEPTOR ACTIVATING PROTEIN 1 ACYLTRANSFERASE PGAP2 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;gene expression#GO:0010467;protein maturation#GO:0051604;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8026161|UniProtKB=A0ACM8F814 A0ACM8F814 LOC8026161 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC115312938|UniProtKB=A0ACM8DSL8 A0ACM8DSL8 LOC115312938 PTHR23104:SF17 MULTIPLE COAGULATION FACTOR DEFICIENCY PROTEIN 2 NEURAL STEM CELL DERIVED NEURONAL SURVIVAL PROTEIN EF-HAND DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115327145|UniProtKB=A0ACM8G595 A0ACM8G595 LOC115327145 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC121838223|UniProtKB=A0ACM8G756 A0ACM8G756 LOC121838223 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115329979|UniProtKB=A0ACM8EFE3 A0ACM8EFE3 LOC115329979 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8033856|UniProtKB=A0ACM8FQ84 A0ACM8FQ84 LOC8033856 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039505|UniProtKB=A0ACM8DKD6 A0ACM8DKD6 PTHR10468:SF12 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1/ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115329649|UniProtKB=A0ACM8EVP0 A0ACM8EVP0 LOC115329649 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115319521|UniProtKB=A0ACM8DZE1 A0ACM8DZE1 LOC115319521 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8032243|UniProtKB=A0ACM8DW79 A0ACM8DW79 LOC8032243 PTHR10846:SF77 SODIUM/POTASSIUM/CALCIUM EXCHANGER SODIUM_POTASSIUM_CALCIUM EXCHANGER 4-RELATED transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;antiporter activity#GO:0015297;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115330222|UniProtKB=A0ACM8F6W6 A0ACM8F6W6 LOC115330222 PTHR11360:SF325 MONOCARBOXYLATE TRANSPORTER EG:103B4.3 PROTEIN transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;monocarboxylic acid transmembrane transporter activity#GO:0008028 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8033166|UniProtKB=A0ACM8E843 A0ACM8E843 LOC8033166 PTHR24255:SF31 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED CUB DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115324537|UniProtKB=A0ACM8E429 A0ACM8E429 LOC115324537 PTHR46539:SF2 E3 UBIQUITIN-PROTEIN LIGASE ATL42 RING-H2 FINGER PROTEIN ATL43 ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121047407|UniProtKB=A0ACM8FKC2 A0ACM8FKC2 LOC121047407 PTHR12482:SF5 LIPASE ROG1-RELATED-RELATED DUF676 DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;lipid metabolic process#GO:0006629 IXOSC|EnsemblGenome=LOC8037287|UniProtKB=A0ACM8DK25 A0ACM8DK25 AP-2sigma PTHR11753:SF6 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP-2 COMPLEX SUBUNIT SIGMA vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC115309344|UniProtKB=A0ACM8DNR2 A0ACM8DNR2 LOC115309344 PTHR12490:SF6 GSK3B-INTERACTING PROTEIN GEO05133P1-RELATED binding#GO:0005488;protein kinase A binding#GO:0051018;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8041525|UniProtKB=A0ACM8E075 A0ACM8E075 LOC8041525 PTHR13622:SF14 THIAMIN PYROPHOSPHOKINASE THIAMINE PYROPHOSPHOKINASE 1 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137;transferase#PC00220 Thiamin metabolism#P02780>Thiamine kinase#P03176 IXOSC|EnsemblGenome=LOC120849158|UniProtKB=A0ACM8F7J8 A0ACM8F7J8 LOC120849158 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC121837218|UniProtKB=A0ACM8G3T5 A0ACM8G3T5 LOC121837218 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115316682|UniProtKB=A0ACM8G8K9 A0ACM8G8K9 LOC115316682 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121837532|UniProtKB=A0ACM8G3H4 A0ACM8G3H4 LOC121837532 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8051826|UniProtKB=A0ACM8EBC4 A0ACM8EBC4 LOC8051826 PTHR11668:SF517 SERINE/THREONINE PROTEIN PHOSPHATASE SERINE_THREONINE-PROTEIN PHOSPHATASE phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8029787|UniProtKB=A0ACM8EWU8 A0ACM8EWU8 LOC8029787 PTHR46212:SF3 PEFLIN PROGRAMMED CELL DEATH PROTEIN 6 IXOSC|EnsemblGenome=LOC8030242|UniProtKB=A0ACM8E2U3 A0ACM8E2U3 LOC8030242 PTHR12967:SF0 PROTEIN SHQ1 HOMOLOG PROTEIN SHQ1 HOMOLOG ribonucleoprotein complex biogenesis#GO:0022613;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;protein-RNA complex assembly#GO:0022618;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120850481|UniProtKB=A0ACM8G038 A0ACM8G038 LOC120850481 PTHR10003:SF106 SUPEROXIDE DISMUTASE CU-ZN -RELATED SUPEROXIDE DISMUTASE [CU-ZN] copper ion binding#GO:0005507;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;response to reactive oxygen species#GO:0000302;cellular response to chemical stress#GO:0062197;superoxide metabolic process#GO:0006801;response to oxidative stress#GO:0006979;cellular process#GO:0009987;cellular oxidant detoxification#GO:0098869;cellular response to oxygen-containing compound#GO:1901701;response to stress#GO:0006950;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;response to stimulus#GO:0050896 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8051518|UniProtKB=A0ACM8E4W8 A0ACM8E4W8 LOC8051518 PTHR11596:SF96 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115314298|UniProtKB=A0ACM8EU24 A0ACM8EU24 LOC115314298 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115323332|UniProtKB=A0ACM8EEG9 A0ACM8EEG9 LOC115323332 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035702|UniProtKB=A0ACM8EW76 A0ACM8EW76 LOC8035702 PTHR13817:SF191 TITIN ZORMIN, ISOFORM J structural protein#PC00211 IXOSC|EnsemblGenome=LOC8026970|UniProtKB=A0ACM8DY28 A0ACM8DY28 centrocortin PTHR19232:SF7 CENTROCORTIN FAMILY MEMBER CENTROCORTIN, ISOFORM A IXOSC|EnsemblGenome=LOC121833186|UniProtKB=A0ACM8FKQ6 A0ACM8FKQ6 LOC121833186 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8033432|UniProtKB=A0ACM8DHX8 A0ACM8DHX8 ECSIT PTHR13113:SF1 ECSIT EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAY, MITOCHONDRIAL innate immune response-activating signaling pathway#GO:0002758;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;response to external biotic stimulus#GO:0043207;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;activation of innate immune response#GO:0002218;immune response#GO:0006955;positive regulation of innate immune response#GO:0045089;positive regulation of response to stimulus#GO:0048584;toll-like receptor 4 signaling pathway#GO:0034142;biological regulation#GO:0065007;immune response-regulating cell surface receptor signaling pathway#GO:0002768;response to other organism#GO:0051707;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;regulation of response to stress#GO:0080134;positive regulation of immune response#GO:0050778;positive regulation of defense response#GO:0031349;regulation of response to stimulus#GO:0048583;regulation of innate immune response#GO:0045088;innate immune response#GO:0045087;positive regulation of response to biotic stimulus#GO:0002833;response to external stimulus#GO:0009605;pattern recognition receptor signaling pathway#GO:0002221;defense response#GO:0006952;regulation of biological process#GO:0050789;immune response-regulating signaling pathway#GO:0002764;response to stimulus#GO:0050896;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;immune system process#GO:0002376;response to biotic stimulus#GO:0009607;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;defense response to other organism#GO:0098542;regulation of response to external stimulus#GO:0032101;cell surface receptor signaling pathway#GO:0007166;immune response-activating signaling pathway#GO:0002757;positive regulation of response to external stimulus#GO:0032103 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>ECSIT#P01349 IXOSC|EnsemblGenome=LOC8026372|UniProtKB=A0ACM8DZG4 A0ACM8DZG4 Ube4B PTHR13931:SF2 UBIQUITINATION FACTOR E4 UBIQUITIN CONJUGATION FACTOR E4 B acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120841609|UniProtKB=A0ACM8ES10 A0ACM8ES10 LOC120841609 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121832849|UniProtKB=A0ACM8FHF2 A0ACM8FHF2 LOC121832849 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033994|UniProtKB=A0ACM8E0D3 A0ACM8E0D3 LOC8033994 PTHR11046:SF0 OLIGORIBONUCLEASE, MITOCHONDRIAL OLIGORIBONUCLEASE, MITOCHONDRIAL hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 endoribonuclease#PC00094;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8033073|UniProtKB=A0ACM8ENP1 A0ACM8ENP1 LOC8033073 PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED IXOSC|EnsemblGenome=LOC121838152|UniProtKB=A0ACM8G8A2 A0ACM8G8A2 LOC121838152 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8031815|UniProtKB=A0ACM8ENF9 A0ACM8ENF9 Spec2 PTHR13502:SF6 CDC42 SMALL EFFECTOR PROTEIN HOMOLOG CDC42 SMALL EFFECTOR PROTEIN HOMOLOG cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8036056|UniProtKB=A0ACM8DSE6 A0ACM8DSE6 LOC8036056 PTHR23351:SF56 FOS TRANSCRIPTION FACTOR-RELATED KAYAK cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC121833295|UniProtKB=A0ACM8FKB4 A0ACM8FKB4 LOC121833295 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121836976|UniProtKB=A0ACM8G225 A0ACM8G225 LOC121836976 PTHR11022:SF80 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LC-RELATED N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;peptidoglycan muralytic activity#GO:0061783;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;pattern recognition receptor activity#GO:0038187;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 response to stimulus#GO:0050896;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to Gram-positive bacterium#GO:0050830;immune response#GO:0006955;defense response#GO:0006952;response to external stimulus#GO:0009605;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response to bacterium#GO:0042742 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC121833254|UniProtKB=A0ACM8FK48 A0ACM8FK48 LOC121833254 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8050573|UniProtKB=A0ACM8DLE4 A0ACM8DLE4 LOC8050573 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8040500|UniProtKB=A0ACM8G6V6 A0ACM8G6V6 LOC8040500 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8035305|UniProtKB=A0ACM8DWB2 A0ACM8DWB2 LOC8035305 PTHR47992:SF257 PROTEIN PHOSPHATASE ALPHABET, ISOFORM E phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 negative regulation of response to stimulus#GO:0048585;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;negative regulation of biological process#GO:0048519;negative regulation of MAPK cascade#GO:0043409;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of cellular response to stress#GO:0080135 cytosol#GO:0005829;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;protein phosphatase#PC00195 DPP signaling pathway#P06213>PPM1A#P06289;Activin beta signaling pathway#P06210>PPM1A#P06237;MYO signaling pathway#P06215>PPM1A#P06317;SCW signaling pathway#P06216>PPM1A#P06332;BMP/activin signaling pathway-drosophila#P06211>PPM1A#P06247;GBB signaling pathway#P06214>PPM1A#P06296;ALP23B signaling pathway#P06209>PPM1A#P06226;DPP-SCW signaling pathway#P06212>PPM1A#P06261 IXOSC|EnsemblGenome=LOC115313175|UniProtKB=A0ACM8F0B5 A0ACM8F0B5 LOC115313175 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8042166|UniProtKB=A0ACM8EEQ6 A0ACM8EEQ6 LOC8042166 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC-RELATED binding#GO:0005488;protein binding#GO:0005515 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 IXOSC|EnsemblGenome=LOC8030277|UniProtKB=A0ACM8ENT3 A0ACM8ENT3 LOC8030277 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8029269|UniProtKB=A0ACM8G0K3 A0ACM8G0K3 LOC8029269 PTHR47644:SF1 AGAP008221-PA PH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046195|UniProtKB=A0ACM8FDJ2 A0ACM8FDJ2 LOC121046195 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120840395|UniProtKB=A0ACM8EPY9 A0ACM8EPY9 LOC120840395 PTHR24377:SF1046 IP01015P-RELATED FI01202P-RELATED C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121045963|UniProtKB=A0ACM8FCR5 A0ACM8FCR5 LOC121045963 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120841781|UniProtKB=A0ACM8ES22 A0ACM8ES22 LOC120841781 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120844175|UniProtKB=A0ACM8EXQ3 A0ACM8EXQ3 LOC120844175 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120848122|UniProtKB=A0ACM8F545 A0ACM8F545 LOC120848122 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8030624|UniProtKB=A0ACM8FGV3 A0ACM8FGV3 LOC8030624 PTHR10285:SF158 URIDINE KINASE SD05789P2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;nucleotide kinase#PC00172 IXOSC|EnsemblGenome=LOC121833762|UniProtKB=A0ACM8FNN7 A0ACM8FNN7 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328239|UniProtKB=A0ACM8E9D4 A0ACM8E9D4 LOC115328239 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043596|UniProtKB=A0ACM8E9M7 A0ACM8E9M7 MED30 PTHR31705:SF4 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 30 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8053647|UniProtKB=A0ACM8EAA2 A0ACM8EAA2 LOC8053647 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837677|UniProtKB=A0ACM8G6P0 A0ACM8G6P0 LOC120837677 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8051696|UniProtKB=A0ACM8E4Y5 A0ACM8E4Y5 dbo PTHR24412:SF491 KELCH PROTEIN KELCH-LIKE PROTEIN 20 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 scaffold/adaptor protein#PC00226 Apoptosis signaling pathway#P00006>Smac/Diablo#P00309 IXOSC|EnsemblGenome=LOC115314469|UniProtKB=A0ACM8DUD2 A0ACM8DUD2 LOC115314469 PTHR21324:SF2 FASTING-INDUCIBLE INTEGRAL MEMBRANE PROTEIN TM6P1-RELATED CWH43-LIKE N-TERMINAL DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115319665|UniProtKB=A0ACM8E0E2 A0ACM8E0E2 LOC115319665 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8034262|UniProtKB=A0ACM8DTI2 A0ACM8DTI2 Fpps PTHR11525:SF23 FARNESYL-PYROPHOSPHATE SYNTHETASE FARNESYL PYROPHOSPHATE SYNTHASE transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;terpenoid biosynthetic process#GO:0016114;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;isoprenoid metabolic process#GO:0006720;organophosphate biosynthetic process#GO:0090407;terpenoid metabolic process#GO:0006721;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 acyltransferase#PC00042;transferase#PC00220 Cholesterol biosynthesis#P00014>Geranyl trans-transferase#P00493 IXOSC|EnsemblGenome=LOC120842922|UniProtKB=A0ACM8EUT1 A0ACM8EUT1 LOC120842922 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115317775|UniProtKB=A0ACM8EYH9 A0ACM8EYH9 LOC115317775 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028236|UniProtKB=A0ACM8EML0 A0ACM8EML0 LOC8028236 PTHR23220:SF83 INTEGRIN ALPHA INTEGRIN ALPHA-PS3-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell-cell adhesion#GO:0098609;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154 signaling receptor complex#GO:0043235;integrin complex#GO:0008305;cell periphery#GO:0071944;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cell surface#GO:0009986;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 integrin#PC00126;cell adhesion molecule#PC00069 Integrin signalling pathway#P00034>Integrin alpha#P00941 IXOSC|EnsemblGenome=LOC120841634|UniProtKB=A0ACM8FJX3 A0ACM8FJX3 LOC120841634 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;circulatory system development#GO:0072359;heart development#GO:0007507;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8039333|UniProtKB=A0ACM8G0E8 A0ACM8G0E8 LOC8039333 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115312847|UniProtKB=A0ACM8G6V9 A0ACM8G6V9 LOC115312847 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035269|UniProtKB=A0ACM8FAA7 A0ACM8FAA7 7B2 PTHR12738:SF0 NEUROENDOCRINE PROTEIN 7B2 NEUROENDOCRINE PROTEIN 7B2 enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of hormone secretion#GO:0046883;regulation of secretion#GO:0051046;regulation of signaling#GO:0023051;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8037406|UniProtKB=A0ACM8EB65 A0ACM8EB65 Ogg1 PTHR10242:SF2 8-OXOGUANINE DNA GLYCOSYLASE N-GLYCOSYLASE_DNA LYASE DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on DNA#GO:0140097;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;base-excision repair#GO:0006284;macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8026933|UniProtKB=A0ACM8DIJ1 A0ACM8DIJ1 elm PTHR46002:SF5 EG:114D9.1 PROTEIN-RELATED EF-HAND DOMAIN-CONTAINING PROTEIN-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC120842086|UniProtKB=A0ACM8ESS9 A0ACM8ESS9 LOC120842086 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024978|UniProtKB=A0ACM8FV19 A0ACM8FV19 LOC8024978 PTHR22767:SF18 N-TERMINAL ACETYLTRANSFERASE-RELATED N(ALPHA)-ACETYLTRANSFERASE 15_16, ISOFORM A enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234 protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC115320635|UniProtKB=A0ACM8F2J7 A0ACM8F2J7 LOC115320635 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120839193|UniProtKB=A0ACM8G480 A0ACM8G480 LOC121047554 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121835315|UniProtKB=A0ACM8FSF3 A0ACM8FSF3 LOC8023994 PTHR45752:SF215 LEUCINE-RICH REPEAT-CONTAINING GH17740P-RELATED signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027272|UniProtKB=A0ACM8E936 A0ACM8E936 or PTHR11753:SF2 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY ADAPTOR PROTEIN COMPLEX AP-3 SMALL CHAIN SIGMA3 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 vesicle coat protein#PC00235;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8031938|UniProtKB=A0ACM8DIZ4 A0ACM8DIZ4 PTHR43394:SF1 ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL ABC TRANSPORTER B FAMILY MEMBER 4 IXOSC|EnsemblGenome=LOC120838001|UniProtKB=A0ACM8EIY8 A0ACM8EIY8 LOC120838001 PTHR12225:SF0 ADHESION REGULATING MOLECULE 1 110 KDA CELL MEMBRANE GLYCOPROTEIN PROTEASOMAL UBIQUITIN RECEPTOR ADRM1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;proteasome complex#GO:0000502;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC121835166|UniProtKB=A0ACM8FSN4 A0ACM8FSN4 LOC121835166 PTHR46060:SF1 MARINER MOS1 TRANSPOSASE-LIKE PROTEIN MOS1 TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115309453|UniProtKB=A0ACM8DNN9 A0ACM8DNN9 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324 calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;chemical homeostasis#GO:0048878;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC115328810|UniProtKB=A0ACM8FAD7 A0ACM8FAD7 LOC115328810 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026503|UniProtKB=A0ACM8FQP4 A0ACM8FQP4 LOC8026503 PTHR23055:SF167 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8038884|UniProtKB=A0ACM8E4K6 A0ACM8E4K6 LOC8038884 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8039638|UniProtKB=A0ACM8DZI9 A0ACM8DZI9 LOC8039638 PTHR24264:SF91 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8032011|UniProtKB=A0ACM8DNS2 A0ACM8DNS2 LOC8032011 PTHR24171:SF9 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39 IXOSC|EnsemblGenome=LOC115328736|UniProtKB=A0ACM8E8N5 A0ACM8E8N5 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848942|UniProtKB=A0ACM8F5V9 A0ACM8F5V9 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320755|UniProtKB=A0ACM8EIF5 A0ACM8EIF5 LOC115320755 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8052221|UniProtKB=A0ACM8EXG8 A0ACM8EXG8 LOC8052221 PTHR20921:SF0 TRANSMEMBRANE PROTEIN 222 TRANSMEMBRANE PROTEIN 222 IXOSC|EnsemblGenome=LOC120839934|UniProtKB=A0ACM8EMF1 A0ACM8EMF1 LOC120839934 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8040070|UniProtKB=A0ACM8E3W9 A0ACM8E3W9 LOC8040070 PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 glycosidase#PC00110;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120844182|UniProtKB=A0ACM8EZ49 A0ACM8EZ49 LOC120844191 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8036790|UniProtKB=A0ACM8EFP3 A0ACM8EFP3 LOC8036790 PTHR12241:SF162 TUBULIN POLYGLUTAMYLASE TUBULIN MONOGLUTAMYLASE TTLL4 catalytic activity#GO:0003824;ligase activity#GO:0016874;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;protein binding#GO:0005515;ligase activity, forming carbon-nitrogen bonds#GO:0016879 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cilium#GO:0005929;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC115332510|UniProtKB=A0ACM8FHL1 A0ACM8FHL1 LOC115332510 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121835677|UniProtKB=A0ACM8FVE8 A0ACM8FVE8 LOC121835677 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC8025093|UniProtKB=A0ACM8DN05 A0ACM8DN05 LOC8025093 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032281|UniProtKB=A0ACM8EP22 A0ACM8EP22 LOC8032281 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8037821|UniProtKB=A0ACM8DI86 A0ACM8DI86 LOC8037821 PTHR31815:SF1 AGAP005329-PA TRANSMEMBRANE PROTEIN 200C IXOSC|EnsemblGenome=LOC8050788|UniProtKB=A0ACM8FP15 A0ACM8FP15 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657 transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115330551|UniProtKB=A0ACM8EHQ1 A0ACM8EHQ1 LOC8042929 PTHR19282:SF431 TETRASPANIN TETRASPANIN 26A, ISOFORM B plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115310907|UniProtKB=A0ACM8DQC2 A0ACM8DQC2 LOC115310907 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8031676|UniProtKB=A0ACM8DYT0 A0ACM8DYT0 LOC8031676 PTHR23078:SF3 VESICULAR-FUSION PROTEIN NSF VESICLE-FUSING ATPASE hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111 localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;intra-Golgi vesicle-mediated transport#GO:0006891;protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;Golgi vesicle transport#GO:0048193;transport#GO:0006810;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 Synaptic vesicle trafficking#P05734>NSF#P05774;Ionotropic glutamate receptor pathway#P00037>NSF#P01020 IXOSC|EnsemblGenome=LOC8036048|UniProtKB=A0ACM8DRZ6 A0ACM8DRZ6 LOC8036048 PTHR23044:SF85 3'-5' EXONUCLEASE ERI1-RELATED ERI1 EXORIBONUCLEASE 3 3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175 RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular component organization#GO:0051129;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;positive regulation of biosynthetic process#GO:0009891;regulation of chromatin organization#GO:1902275;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;negative regulation of cellular process#GO:0048523;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular component organization#GO:0051128;regulation of biological process#GO:0050789;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular component biogenesis#GO:0044085;RNA 3'-end processing#GO:0031123;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC8050978|UniProtKB=A0ACM8FKI3 A0ACM8FKI3 VGlut PTHR11662:SF456 SOLUTE CARRIER FAMILY 17 VESICULAR GLUTAMATE TRANSPORTER, ISOFORM A carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;L-glutamate transmembrane transporter activity#GO:0005313;dicarboxylic acid transmembrane transporter activity#GO:0005310 chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;trans-synaptic signaling#GO:0099537;cellular localization#GO:0051641;regulation of synapse structure or activity#GO:0050803;cell communication#GO:0007154;localization#GO:0051179;regulation of biological quality#GO:0065008;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter transport#GO:0006836;synaptic transmission, glutamatergic#GO:0035249;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234 presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cell junction#GO:0030054;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8031682|UniProtKB=A0ACM8DYC3 A0ACM8DYC3 PTHR46513:SF13 VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED EGF-LIKE DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115316694|UniProtKB=A0ACM8ERJ9 A0ACM8ERJ9 LOC115316694 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120840900|UniProtKB=A0ACM8FFV9 A0ACM8FFV9 LOC120840900 PTHR21399:SF0 CHLORIDE CONDUCTANCE REGULATORY PROTEIN ICLN METHYLOSOME SUBUNIT PICLN nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;spliceosomal snRNP assembly#GO:0000387;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607 Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;spliceosomal complex#GO:0005681;nucleus#GO:0005634 transporter#PC00227 IXOSC|EnsemblGenome=LOC115311613|UniProtKB=A0ACM8DR91 A0ACM8DR91 LOC115311613 PTHR12213:SF0 CORRINOID ADENOSYLTRANSFERASE CORRINOID ADENOSYLTRANSFERASE MMAB transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120839143|UniProtKB=A0ACM8FS41 A0ACM8FS41 LOC120839143 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8036409|UniProtKB=A0ACM8E2Z0 A0ACM8E2Z0 Dhc64C PTHR45703:SF41 DYNEIN HEAVY CHAIN CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1 microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC8039179|UniProtKB=A0ACM8E2N0 A0ACM8E2N0 gammaCOP PTHR10261:SF0 COATOMER SUBUNIT GAMMA COATOMER SUBUNIT GAMMA-2 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC121838454|UniProtKB=A0ACM8G928 A0ACM8G928 LOC121838454 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842309|UniProtKB=A0ACM8EUL3 A0ACM8EUL3 LOC120842309 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 IXOSC|EnsemblGenome=LOC120837136|UniProtKB=A0ACM8EHC7 A0ACM8EHC7 LOC120837136 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121836563|UniProtKB=A0ACM8FZ51 A0ACM8FZ51 LOC121836563 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045858|UniProtKB=A0ACM8FVT9 A0ACM8FVT9 LOC121045858 PTHR33064:SF47 POL PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836838|UniProtKB=A0ACM8EG02 A0ACM8EG02 LOC120836838 PTHR13723:SF323 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 6 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;external encapsulating structure organization#GO:0045229;metabolic process#GO:0008152;proteolysis#GO:0006508;extracellular structure organization#GO:0043062;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8023788|UniProtKB=A0ACM8F7Z1 A0ACM8F7Z1 LOC8023788 PTHR12308:SF89 ANOCTAMIN ANOCTAMIN intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319 transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;lipid localization#GO:0010876;localization#GO:0051179;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8043552|UniProtKB=A0ACM8EIP3 A0ACM8EIP3 LOC8043552 PTHR24235:SF34 NEUROPEPTIDE Y RECEPTOR NEUROPEPTIDE Y RECEPTOR 11-RELATED molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8040316|UniProtKB=A0ACM8DKK3 A0ACM8DKK3 mbf1 PTHR10245:SF15 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 MULTIPROTEIN BRIDGING FACTOR 1 ENDOTHELIAL DIFFERENTIATION-RELATED FACTOR 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893 IXOSC|EnsemblGenome=LOC8040283|UniProtKB=A0ACM8DKJ6 A0ACM8DKJ6 LOC8040283 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC8040170|UniProtKB=A0ACM8EF26 A0ACM8EF26 LOC8040170 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8025689|UniProtKB=A0ACM8G8R3 A0ACM8G8R3 LOC8025689 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8041322|UniProtKB=A0ACM8EYW8 A0ACM8EYW8 LOC8041322 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293 metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8052878|UniProtKB=A0ACM8E8A0 A0ACM8E8A0 LOC8052878 PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8028184|UniProtKB=A0ACM8EYK4 A0ACM8EYK4 LOC8028184 PTHR10264:SF136 BAND 7 PROTEIN-RELATED BAND 7 DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;transporter regulator activity#GO:0141108;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC115324034|UniProtKB=A0ACM8EMU2 A0ACM8EMU2 LOC115324034 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842303|UniProtKB=A0ACM8ETI7 A0ACM8ETI7 LOC120842303 PTHR11006:SF60 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 9 transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;histone modifying activity#GO:0140993 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120843345|UniProtKB=A0ACM8EVY8 A0ACM8EVY8 LOC120843345 PTHR24394:SF75 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8033740|UniProtKB=A0ACM8FLT1 A0ACM8FLT1 LOC8033740 PTHR46188:SF1 BOLA-LIKE PROTEIN 3 BOLA-LIKE PROTEIN 3 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 IXOSC|EnsemblGenome=LOC8035262|UniProtKB=A0ACM8ESP9 A0ACM8ESP9 LOC8035262 PTHR24419:SF18 INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE SERINE_THREONINE-PROTEIN KINASE HASPIN histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;histone kinase activity#GO:0035173;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;biological regulation#GO:0065007;signaling#GO:0023052 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120837113|UniProtKB=A0ACM8FYQ8 A0ACM8FYQ8 LOC120837113 PTHR43767:SF1 LONG-CHAIN-FATTY-ACID--COA LIGASE NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC8039982|UniProtKB=A0ACM8EJM0 A0ACM8EJM0 ZnT35C PTHR11562:SF17 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER LD05335P zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;zinc ion transmembrane transport#GO:0071577;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8037872|UniProtKB=A0ACM8DIA8 A0ACM8DIA8 LOC8037872 PTHR31993:SF4 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 UBA-LIKE DOMAIN-CONTAINING PROTEIN 2 IXOSC|EnsemblGenome=LOC120840723|UniProtKB=A0ACM8G8D9 A0ACM8G8D9 LOC120840723 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037525|UniProtKB=A0ACM8DXU3 A0ACM8DXU3 LOC8037525 PTHR11630:SF48 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA HELICASE MCM9 nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA recombination#GO:0006310;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8035979|UniProtKB=A0ACM8EMG6 A0ACM8EMG6 LOC8035979 PTHR11699:SF211 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1 oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC8041456|UniProtKB=A0ACM8DV96 A0ACM8DV96 Rab14 PTHR24073:SF185 DRAB5-RELATED RAS-RELATED PROTEIN RAB-14 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 organelle assembly#GO:0070925;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;vacuole organization#GO:0007033;cellular localization#GO:0051641;localization#GO:0051179;Golgi to endosome transport#GO:0006895;cellular component organization#GO:0016043;cytosolic transport#GO:0016482;endocytosis#GO:0006897;lytic vacuole organization#GO:0080171;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;phagocytosis#GO:0006909;intracellular transport#GO:0046907;phagolysosome assembly#GO:0001845;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;lysosome organization#GO:0007040;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607 endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular vesicle#GO:0097708;vesicle#GO:0031982 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC121835921|UniProtKB=A0ACM8FX54 A0ACM8FX54 LOC121835921 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8029967|UniProtKB=A0ACM8DJ51 A0ACM8DJ51 LOC8029967 PTHR31051:SF1 PROTEASOME ASSEMBLY CHAPERONE 3 PROTEASOME ASSEMBLY CHAPERONE 3 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8040065|UniProtKB=A0ACM8DKH7 A0ACM8DKH7 mRpL3 PTHR11229:SF8 50S RIBOSOMAL PROTEIN L3 LARGE RIBOSOMAL SUBUNIT PROTEIN UL3M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8043810|UniProtKB=A0ACM8FKT4 A0ACM8FKT4 eya PTHR10190:SF16 EYES ABSENT PROTEIN PHOSPHATASE EYA catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721 positive regulation of metabolic process#GO:0009893;regulation of cellular response to stress#GO:0080135;positive regulation of DNA metabolic process#GO:0051054;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of response to stress#GO:0080134;developmental process#GO:0032502;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;cellular developmental process#GO:0048869;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;positive regulation of DNA repair#GO:0045739 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC120838118|UniProtKB=A0ACM8FQL0 A0ACM8FQL0 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8035936|UniProtKB=A0ACM8DW11 A0ACM8DW11 LOC8035936 PTHR11675:SF43 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8025031|UniProtKB=A0ACM8EQB4 A0ACM8EQB4 LOC8025031 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120846091|UniProtKB=A0ACM8F1H6 A0ACM8F1H6 LOC120846091 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028078|UniProtKB=A0ACM8FS77 A0ACM8FS77 Dgk PTHR11255:SF48 DIACYLGLYCEROL KINASE DIACYLGLYCEROL KINASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 kinase#PC00137;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8028761|UniProtKB=A0ACM8DN37 A0ACM8DN37 LTV1 PTHR21531:SF0 LOW-TEMPERATURE VIABILITY PROTEIN LTV1-RELATED PROTEIN LTV1 HOMOLOG establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;organelle localization#GO:0051640;ribosome biogenesis#GO:0042254;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular transport#GO:0046907;ribosomal subunit export from nucleus#GO:0000054;ribosomal small subunit biogenesis#GO:0042274;transport#GO:0006810 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115310299|UniProtKB=A0ACM8FYK1 A0ACM8FYK1 LOC115310299 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115317760|UniProtKB=A0ACM8FXN9 A0ACM8FXN9 LOC115317760 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC8034830|UniProtKB=A0ACM8FJV9 A0ACM8FJV9 PTHR24213:SF9 ACTIN-BINDING LIM PROTEIN UNCOORDINATED 115A, ISOFORM B-RELATED actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;lamellipodium assembly#GO:0030032;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;actin cytoskeleton#GO:0015629 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 Axon guidance mediated by netrin#P00009>Ablim#P00358 IXOSC|EnsemblGenome=LOC121047108|UniProtKB=A0ACM8FEB0 A0ACM8FEB0 LOC121047108 PTHR10609:SF28 BIOTINIDASE-RELATED CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8029815|UniProtKB=A0ACM8DRU6 A0ACM8DRU6 Vps20 PTHR22761:SF5 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 6 membrane assembly#GO:0071709;cellular component organization#GO:0016043;late endosome to vacuole transport#GO:0045324;cellular localization#GO:0051641;localization#GO:0051179;nuclear membrane organization#GO:0071763;cellular process#GO:0009987;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;multivesicular body sorting pathway#GO:0071985;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular component assembly#GO:0022607;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;nuclear envelope organization#GO:0006998;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;endosomal transport#GO:0016197;nucleus organization#GO:0006997;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;endomembrane system#GO:0012505;nucleus#GO:0005634;vesicle membrane#GO:0012506;membrane#GO:0016020 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8033083|UniProtKB=A0ACM8EMN6 A0ACM8EMN6 LOC8033083 PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED IXOSC|EnsemblGenome=LOC8027712|UniProtKB=A0ACM8E3C7 A0ACM8E3C7 LOC8027712 PTHR11923:SF51 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 FI02050P-RELATED cargo receptor activity#GO:0038024 membrane#GO:0016020;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8026866|UniProtKB=A0ACM8EFV3 A0ACM8EFV3 LOC8026866 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED IXOSC|EnsemblGenome=LOC115319126|UniProtKB=A0ACM8FFL8 A0ACM8FFL8 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115309924|UniProtKB=A0ACM8DP33 A0ACM8DP33 LOC115309924 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115312009|UniProtKB=A0ACM8DRT0 A0ACM8DRT0 sgl PTHR11374:SF3 UDP-GLUCOSE DEHYDROGENASE/UDP-MANNAC DEHYDROGENASE UDP-GLUCOSE 6-DEHYDROGENASE oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8041629|UniProtKB=A0ACM8E1W7 A0ACM8E1W7 Spred PTHR11202:SF3 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN FAMILY MEMBER SPROUTY-RELATED PROTEIN WITH EVH-1 DOMAIN, ISOFORM C binding#GO:0005488;kinase binding#GO:0019900;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of cellular process#GO:0048523;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8043106|UniProtKB=A0ACM8DKZ8 A0ACM8DKZ8 LOC8043106 PTHR24399:SF70 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8024334|UniProtKB=A0ACM8FLN2 A0ACM8FLN2 Pop1 PTHR22731:SF3 RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1 RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;ribonuclease P activity#GO:0004526;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;organelle lumen#GO:0043233;nucleolar ribonuclease P complex#GO:0005655;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;multimeric ribonuclease P complex#GO:0030681;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991 endoribonuclease#PC00094;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115318058|UniProtKB=A0ACM8ENX4 A0ACM8ENX4 LOC115318058 PTHR46925:SF2 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED G PROTEIN-COUPLED RECEPTOR TKR-1-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8031200|UniProtKB=A0ACM8F259 A0ACM8F259 LOC8031200 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;organelle#GO:0043226;oxidoreductase complex#GO:1990204;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120843014|UniProtKB=A0ACM8EV53 A0ACM8EV53 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8035699|UniProtKB=A0ACM8E796 A0ACM8E796 LOC8035699 PTHR46232:SF1 SMARCE1 REGULATOR OF CHROMATIN SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY E MEMBER 1 protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;transcription factor binding#GO:0008134;nuclear receptor binding#GO:0016922;binding#GO:0005488 negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 Wnt signaling pathway#P00057>SWI/SNF#P01435 IXOSC|EnsemblGenome=LOC115308930|UniProtKB=A0ACM8DN54 A0ACM8DN54 PTHR24348:SF79 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED AUTOPHAGY-RELATED 1, ISOFORM B protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 system development#GO:0048731;vacuole organization#GO:0007033;anatomical structure development#GO:0048856;organelle assembly#GO:0070925;piecemeal microautophagy of the nucleus#GO:0034727;developmental cell growth#GO:0048588;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;response to starvation#GO:0042594;neurogenesis#GO:0022008;regulation of catabolic process#GO:0009894;developmental growth#GO:0048589;cellular developmental process#GO:0048869;mitophagy#GO:0000423;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;autophagy of mitochondrion#GO:0000422;plasma membrane bounded cell projection organization#GO:0120036;macroautophagy#GO:0016236;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of metabolic process#GO:0019222;axon development#GO:0061564;reticulophagy#GO:0061709;response to nutrient levels#GO:0031667;axonogenesis#GO:0007409;neuron development#GO:0048666;process utilizing autophagic mechanism#GO:0061919;developmental growth involved in morphogenesis#GO:0060560;neuron projection extension#GO:1990138;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell differentiation#GO:0030154;response to stimulus#GO:0050896;cell projection organization#GO:0030030;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of autophagy#GO:0010506;autophagosome assembly#GO:0000045;cell projection morphogenesis#GO:0048858;cell growth#GO:0016049;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;growth#GO:0040007;neuron differentiation#GO:0030182;metabolic process#GO:0008152;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;axon extension#GO:0048675;cellular component assembly#GO:0022607;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;neuron projection development#GO:0031175 autophagosome#GO:0005776;intracellular organelle#GO:0043229;phagophore assembly site#GO:0000407;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120839494|UniProtKB=A0ACM8ELU2 A0ACM8ELU2 LOC120839494 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115310987|UniProtKB=A0ACM8FZN4 A0ACM8FZN4 LOC115310987 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040323|UniProtKB=A0ACM8E8W1 A0ACM8E8W1 LOC8040323 PTHR24412:SF396 KELCH PROTEIN INFLUENZA VIRUS NS1A-BINDING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121838514|UniProtKB=A0ACM8G915 A0ACM8G915 LOC121838514 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC121837488|UniProtKB=A0ACM8G4P0 A0ACM8G4P0 LOC121837488 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843058|UniProtKB=A0ACM8G197 A0ACM8G197 LOC120843058 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8031449|UniProtKB=A0ACM8DQN0 A0ACM8DQN0 PTHR20933:SF4 F-BOX ONLY PROTEIN 33 F-BOX INVOLVED IN POLYQ PATHOGENESIS, ISOFORM A IXOSC|EnsemblGenome=LOC121835104|UniProtKB=A0ACM8FSA8 A0ACM8FSA8 LOC121835104 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular process#GO:0009987;heart development#GO:0007507;circulatory system development#GO:0072359;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;system development#GO:0048731 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121837294|UniProtKB=A0ACM8G344 A0ACM8G344 LOC121837294 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051883|UniProtKB=A0ACM8EG37 A0ACM8EG37 LOC8051883 PTHR11675:SF101 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 5 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120849598|UniProtKB=A0ACM8F8F1 A0ACM8F8F1 LOC120849598 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034120|UniProtKB=A0ACM8EDI3 A0ACM8EDI3 LOC8034120 PTHR16088:SF3 YY1 ASSOCIATED PROTEIN-RELATED GON-4-LIKE PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC8026174|UniProtKB=A0ACM8FQL4 A0ACM8FQL4 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121834578|UniProtKB=A0ACM8FQR4 A0ACM8FQR4 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115312592|UniProtKB=A0ACM8DSA5 A0ACM8DSA5 LOC115312592 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE response to stimulus#GO:0050896;protein folding#GO:0006457;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;protein refolding#GO:0042026;protein maturation#GO:0051604;gene expression#GO:0010467;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;response to stress#GO:0006950;response to heat#GO:0009408;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC120836311|UniProtKB=A0ACM8FSE9 A0ACM8FSE9 LOC120836311 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cell leading edge#GO:0031252;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253 IXOSC|EnsemblGenome=LOC8043520|UniProtKB=A0ACM8E973 A0ACM8E973 LOC8043520 PTHR43829:SF33 AQUAPORIN OR AQUAGLYCEROPORIN RELATED AQUAPORIN-9 passive transmembrane transporter activity#GO:0022803;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;carbohydrate transmembrane transporter activity#GO:0015144 transport#GO:0006810;carbohydrate transport#GO:0008643;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;water transport#GO:0006833;organic hydroxy compound transport#GO:0015850;fluid transport#GO:0042044;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219 basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;membrane#GO:0016020;basal plasma membrane#GO:0009925;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8036700|UniProtKB=A0ACM8DVU0 A0ACM8DVU0 LOC8036700 PTHR15835:SF6 NUCLEAR-INTERACTING PARTNER OF ALK ZINC FINGER C3HC-TYPE PROTEIN 1 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115309308|UniProtKB=A0ACM8DNH5 A0ACM8DNH5 LOC115309308 PTHR19432:SF35 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120841627|UniProtKB=A0ACM8FQY2 A0ACM8FQY2 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8034623|UniProtKB=A0ACM8E7Y5 A0ACM8E7Y5 LOC8034623 PTHR11544:SF148 COLD SHOCK DOMAIN CONTAINING PROTEINS LD37574P binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8023407|UniProtKB=A0ACM8EG44 A0ACM8EG44 LOC8023407 PTHR16517:SF162 TUBBY-RELATED PROTEIN KING TUBBY localization#GO:0051179;protein localization to organelle#GO:0033365;protein localization to cilium#GO:0061512;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115318783|UniProtKB=A0ACM8EU08 A0ACM8EU08 LOC115318783 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8050955|UniProtKB=A0ACM8EA98 A0ACM8EA98 LOC8050955 PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 IXOSC|EnsemblGenome=LOC115331017|UniProtKB=A0ACM8F7G9 A0ACM8F7G9 LOC115331017 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039473|UniProtKB=A0ACM8FYX0 A0ACM8FYX0 mbo PTHR13257:SF0 NUCLEOPORIN NUP84-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP88 localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168;organelle localization#GO:0051640;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;RNA transport#GO:0050658;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;establishment of protein localization to organelle#GO:0072594;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;ribosomal subunit export from nucleus#GO:0000054;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;protein localization to nucleus#GO:0034504;nitrogen compound transport#GO:0071705;macromolecule biosynthetic process#GO:0009059;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;protein transport#GO:0015031;protein import into nucleus#GO:0006606;ribosome biogenesis#GO:0042254;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;gene expression#GO:0010467;protein export from nucleus#GO:0006611;cellular component biogenesis#GO:0044085;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 transporter#PC00227 IXOSC|EnsemblGenome=LOC8044132|UniProtKB=A0ACM8DL61 A0ACM8DL61 LOC8044132 PTHR13369:SF0 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE C-TERMINAL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835013|UniProtKB=A0ACM8FSX1 A0ACM8FSX1 LOC121835013 PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;catabolic process#GO:0009056 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8041743|UniProtKB=A0ACM8F170 A0ACM8F170 LOC8041743 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC8053981|UniProtKB=A0ACM8EFE0 A0ACM8EFE0 LOC8053981 PTHR23280:SF25 4.1 G PROTEIN MOESIN_EZRIN_RADIXIN HOMOLOG 1 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basolateral plasma membrane#GO:0016323;basal part of cell#GO:0045178;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115321531|UniProtKB=A0ACM8E8M5 A0ACM8E8M5 LOC115328062 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030193|UniProtKB=A0ACM8DYF2 A0ACM8DYF2 LOC8030193 PTHR11532:SF96 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D-LIKE PROTEIN metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;peptide metabolic process#GO:0006518;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 IXOSC|EnsemblGenome=LOC115320979|UniProtKB=A0ACM8EYB2 A0ACM8EYB2 LOC115320979 PTHR10194:SF142 RAS GTPASE-ACTIVATING PROTEINS NEUROFIBROMIN GTPase-activating protein#PC00257 EGF receptor signaling pathway#P00018>GAP#P00546 IXOSC|EnsemblGenome=LOC121836983|UniProtKB=A0ACM8G0P6 A0ACM8G0P6 LOC121836983 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8038377|UniProtKB=A0ACM8E3V3 A0ACM8E3V3 LOC8038377 PTHR10738:SF0 PROTEIN ARGININE N-METHYLTRANSFERASE 5 PROTEIN ARGININE N-METHYLTRANSFERASE 5 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8043581|UniProtKB=A0ACM8DUJ3 A0ACM8DUJ3 LOC8043581 PTHR22722:SF14 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED MEGALIN, ISOFORM A hormone binding#GO:0042562;binding#GO:0005488 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;receptor-mediated endocytosis#GO:0006898;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8030358|UniProtKB=A0ACM8E212 A0ACM8E212 LOC8030358 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120843831|UniProtKB=A0ACM8EWP7 A0ACM8EWP7 LOC120843831 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115329438|UniProtKB=A0ACM8ETB4 A0ACM8ETB4 LOC115329438 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115320167|UniProtKB=A0ACM8E0K6 A0ACM8E0K6 LOC115320167 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115315747|UniProtKB=A0ACM8EGQ0 A0ACM8EGQ0 LOC115315747 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8052274|UniProtKB=A0ACM8EFS4 A0ACM8EFS4 LOC8052274 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8034492|UniProtKB=A0ACM8DN52 A0ACM8DN52 Nelf-E PTHR17250:SF0 NEGATIVE ELONGATION FACTOR E NEGATIVE ELONGATION FACTOR E negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of DNA-templated transcription elongation#GO:0032784;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC8023944|UniProtKB=A0ACM8DMG5 A0ACM8DMG5 Invadolysin PTHR10942:SF0 LEISHMANOLYSIN-LIKE PEPTIDASE LEISHMANOLYSIN-LIKE PEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115330154|UniProtKB=A0ACM8EAT6 A0ACM8EAT6 PTHR47972:SF45 KINESIN-LIKE PROTEIN KLP-3 PROTEIN CLARET SEGREGATIONAL microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC8053601|UniProtKB=A0ACM8E8I7 A0ACM8E8I7 Gdap2 PTHR11106:SF72 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2 IXOSC|EnsemblGenome=LOC120842246|UniProtKB=A0ACM8EUF8 A0ACM8EUF8 LOC120842246 PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8027129|UniProtKB=A0ACM8E6C3 A0ACM8E6C3 Miro PTHR46819:SF3 EF-HAND CALCIUM-BINDING DOMAIN-CONTAINING PROTEIN 7 SMALL GTPASE SUPERFAMILY-RELATED calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC121834700|UniProtKB=A0ACM8FQI1 A0ACM8FQI1 PTHR45762:SF3 ZINC FINGER RNA-BINDING PROTEIN ZINC-FINGER PROTEIN AT 72D, ISOFORM B nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121834223|UniProtKB=A0ACM8FP96 A0ACM8FP96 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8040250|UniProtKB=A0ACM8ED36 A0ACM8ED36 LOC8040250 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120844863|UniProtKB=A0ACM8EZW8 A0ACM8EZW8 LOC120844863 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 transferase#PC00220 IXOSC|EnsemblGenome=LOC115309651|UniProtKB=A0ACM8DNV6 A0ACM8DNV6 LOC115309651 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115323219|UniProtKB=A0ACM8E403 A0ACM8E403 LOC115323219 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8023862|UniProtKB=A0ACM8G2T0 A0ACM8G2T0 LOC8023862 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115323942|UniProtKB=A0ACM8E4S8 A0ACM8E4S8 LOC115323942 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115315116|UniProtKB=A0ACM8F6U2 A0ACM8F6U2 LOC115315116 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC8036939|UniProtKB=A0ACM8E4Q0 A0ACM8E4Q0 cib PTHR20940:SF1 TETRA THYMOSIN CIBOULOT, ISOFORM A protein binding#GO:0005515;binding#GO:0005488;actin monomer binding#GO:0003785;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115313374|UniProtKB=A0ACM8DSY6 A0ACM8DSY6 LOC115313374 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8026957|UniProtKB=A0ACM8FFI0 A0ACM8FFI0 PTHR22808:SF1 NCL1 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING TRNA (CYTOSINE(34)-C(5))-METHYLTRANSFERASE tRNA methyltransferase activity#GO:0008175;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a tRNA#GO:0140101;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;ribosomal large subunit assembly#GO:0000027;mitochondrial ribosome assembly#GO:0061668;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial large ribosomal subunit assembly#GO:1902775;rRNA processing#GO:0006364;RNA methylation#GO:0001510;protein-RNA complex assembly#GO:0022618;macromolecule modification#GO:0043412;organelle assembly#GO:0070925;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;tRNA methylation#GO:0030488;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;tRNA processing#GO:0008033;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;tRNA modification#GO:0006400;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;tRNA wobble base modification#GO:0002097;RNA metabolic process#GO:0016070;methylation#GO:0032259;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;ribosome biogenesis#GO:0042254;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8027575|UniProtKB=A0ACM8DJ76 A0ACM8DJ76 LOC8027575 PTHR11362:SF82 PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN PHOSPHATIDYLETHANOLAMINE-BINDING PROTEIN 4 protease inhibitor#PC00191 FGF signaling pathway#P00021>RKIP#P00630;EGF receptor signaling pathway#P00018>RKIP#P00548 IXOSC|EnsemblGenome=LOC8032771|UniProtKB=A0ACM8DGT5 A0ACM8DGT5 LOC8032771 PTHR16134:SF1 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX AND LEUCINE-RICH PROTEIN 22 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;photoperiodism#GO:0009648;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to external stimulus#GO:0009605;response to radiation#GO:0009314;cellular process#GO:0009987;regulation of circadian rhythm#GO:0042752;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;response to light stimulus#GO:0009416;response to stimulus#GO:0050896;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115327983|UniProtKB=A0ACM8FAJ6 A0ACM8FAJ6 LOC115327983 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC120838646|UniProtKB=A0ACM8EKC8 A0ACM8EKC8 LOC120838646 PTHR10749:SF7 PHOSPHORYLASE B KINASE REGULATORY SUBUNIT PHOSPHORYLASE B KINASE REGULATORY SUBUNIT ALPHA-RELATED protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 kinase activator#PC00138 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 IXOSC|EnsemblGenome=LOC8051700|UniProtKB=A0ACM8DLB9 A0ACM8DLB9 LOC8051700 PTHR42643:SF51 IONOTROPIC RECEPTOR 20A-RELATED SUBFAMILY NOT NAMED transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121836708|UniProtKB=A0ACM8G172 A0ACM8G172 LOC121836708 PTHR24230:SF141 G-PROTEIN COUPLED RECEPTOR TRACE AMINE-ASSOCIATED RECEPTOR 8B molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115317108|UniProtKB=A0ACM8DX61 A0ACM8DX61 LOC115317108 PTHR46363:SF1 DEOXYRIBONUCLEASE TATDN2-RELATED 3'-5' RNA NUCLEASE TATDN2 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC115322019|UniProtKB=A0ACM8F6P2 A0ACM8F6P2 LOC115322019 PTHR24351:SF230 RIBOSOMAL PROTEIN S6 KINASE RIBOSOMAL PROTEIN S6 KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TORC1 signaling#GO:0038202;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;TOR signaling#GO:0031929;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;p53 pathway by glucose deprivation#P04397>S6K#P04636;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 IXOSC|EnsemblGenome=LOC120838112|UniProtKB=A0ACM8EJ17 A0ACM8EJ17 Fip1 PTHR13484:SF11 FIP1-LIKE 1 PROTEIN FACTOR INTERACTING WITH POLY(A) POLYMERASE 1 biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8026825|UniProtKB=A0ACM8ED99 A0ACM8ED99 LOC8026825 PTHR11071:SF593 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE E intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120841798|UniProtKB=A0ACM8ESH3 A0ACM8ESH3 LOC120841798 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309279|UniProtKB=A0ACM8FAK2 A0ACM8FAK2 LOC115309279 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8033734|UniProtKB=A0ACM8DZR0 A0ACM8DZR0 LOC8033734 PTHR24373:SF406 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN TARTAN, ISOFORM B molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8031077|UniProtKB=A0ACM8DQA7 A0ACM8DQA7 LOC8031077 PTHR10414:SF71 ETHANOLAMINEPHOSPHOTRANSFERASE FI05338P transferase#PC00220 IXOSC|EnsemblGenome=LOC120843086|UniProtKB=A0ACM8EWC1 A0ACM8EWC1 LOC120843086 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031745|UniProtKB=A0ACM8E2P4 A0ACM8E2P4 LOC8031745 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC8041234|UniProtKB=A0ACM8F4N2 A0ACM8F4N2 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121838526|UniProtKB=A0ACM8G8K1 A0ACM8G8K1 LOC121838526 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120842213|UniProtKB=A0ACM8ET97 A0ACM8ET97 LOC120842213 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843718|UniProtKB=A0ACM8G2R1 A0ACM8G2R1 LOC120843718 PTHR31569:SF9 SWIM-TYPE DOMAIN-CONTAINING PROTEIN SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836690|UniProtKB=A0ACM8FZ57 A0ACM8FZ57 LOC121836690 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8031949|UniProtKB=A0ACM8EE59 A0ACM8EE59 PTHR13363:SF6 RING FINGER AND SRY DOMAIN-CONTAINING RING FINGER AND SPRY DOMAIN-CONTAINING PROTEIN 1 ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8024413|UniProtKB=A0ACM8FB98 A0ACM8FB98 PTHR47972:SF45 KINESIN-LIKE PROTEIN KLP-3 PROTEIN CLARET SEGREGATIONAL microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC115309481|UniProtKB=A0ACM8DNW5 A0ACM8DNW5 LOC115309481 PTHR12113:SF31 DICKKOPF3-LIKE 3 DICKKOPF N-TERMINAL CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;signaling receptor inhibitor activity#GO:0030547;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor regulator activity#GO:0030545 regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of cell communication#GO:0010648;regulation of canonical Wnt signaling pathway#GO:0060828;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8026951|UniProtKB=A0ACM8DSI7 A0ACM8DSI7 LOC8026951 PTHR10127:SF905 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8027271|UniProtKB=A0ACM8E1X7 A0ACM8E1X7 LOC8027271 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8028466|UniProtKB=A0ACM8E8S5 A0ACM8E8S5 Ctr9 PTHR14027:SF2 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 RNA POLYMERASE-ASSOCIATED PROTEIN CTR9 HOMOLOG RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;Cdc73/Paf1 complex#GO:0016593;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II, holoenzyme#GO:0016591;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8050636|UniProtKB=A0ACM8E4K8 A0ACM8E4K8 LOC8050636 PTHR12787:SF0 RIBOSOMAL RNA-PROCESSING PROTEIN 8 RIBOSOMAL RNA-PROCESSING PROTEIN 8 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649 cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;nucleolus organization#GO:0007000 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 IXOSC|EnsemblGenome=LOC120850598|UniProtKB=A0ACM8FST0 A0ACM8FST0 LOC120850598 PTHR14555:SF3 MYELIN-ASSOCIATED OLIGODENDROCYTIC BASIC PROTEIN MOBP -RELATED RABBD DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;myosin binding#GO:0017022;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 myelin protein#PC00161 IXOSC|EnsemblGenome=LOC120837120|UniProtKB=A0ACM8EHL5 A0ACM8EHL5 LOC120837120 PTHR24083:SF154 NUCLEAR HORMONE RECEPTOR PROTEIN DISSATISFACTION sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8028719|UniProtKB=A0ACM8FCP2 A0ACM8FCP2 LOC8028719 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437 microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8051907|UniProtKB=A0ACM8DU07 A0ACM8DU07 Dsor1 PTHR48013:SF9 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE DSOR1 transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;MAPK cascade#GO:0000165;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 EGF receptor signaling pathway#P00018>MEK1-2#P00559;Endothelin signaling pathway#P00019>MEK#P00572;PDGF signaling pathway#P00047>MEK#P01162;FGF signaling pathway#P00021>MEK1-2#P00642;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891 IXOSC|EnsemblGenome=LOC115319928|UniProtKB=A0ACM8EY92 A0ACM8EY92 LOC115319928 PTHR15999:SF2 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115313459|UniProtKB=A0ACM8G032 A0ACM8G032 LOC115313459 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8039420|UniProtKB=A0ACM8G2G5 A0ACM8G2G5 LOC8039420 PTHR23055:SF198 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 1 cyclase regulator activity#GO:0010851;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;calcium ion binding#GO:0005509;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;molecular function activator activity#GO:0140677;cation binding#GO:0043169;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8053924|UniProtKB=A0ACM8E1A8 A0ACM8E1A8 LOC8053924 PTHR10131:SF166 TNF RECEPTOR ASSOCIATED FACTOR RING FINGER PROTEIN 151 signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;signal transduction#GO:0007165;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115325377|UniProtKB=A0ACM8E5K2 A0ACM8E5K2 Dbp73D PTHR24031:SF68 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX51 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC115332271|UniProtKB=A0ACM8EE33 A0ACM8EE33 LOC115332271 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8025155|UniProtKB=A0ACM8DPC1 A0ACM8DPC1 SdhA PTHR11632:SF51 SUCCINATE DEHYDROGENASE 2 FLAVOPROTEIN SUBUNIT SUCCINATE DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN SUBUNIT, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidative phosphorylation#GO:0006119;ATP synthesis coupled electron transport#GO:0042773;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;metabolic process#GO:0008152;aerobic electron transport chain#GO:0019646;generation of precursor metabolites and energy#GO:0006091;mitochondrial electron transport, succinate to ubiquinone#GO:0006121;anaerobic respiration#GO:0009061;electron transport chain#GO:0022900;mitochondrial ATP synthesis coupled electron transport#GO:0042775;respiratory electron transport chain#GO:0022904;cellular process#GO:0009987 respiratory chain complex II (succinate dehydrogenase)#GO:0045273;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cell periphery#GO:0071944;respiratory chain complex#GO:0098803;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;mitochondrion#GO:0005739 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8031807|UniProtKB=A0ACM8FUQ5 A0ACM8FUQ5 LOC8031807 PTHR11675:SF134 N-ACETYLGALACTOSAMINYLTRANSFERASE N-ACETYLGALACTOSAMINYLTRANSFERASE 4-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8042778|UniProtKB=A0ACM8DKZ5 A0ACM8DKZ5 LOC8042778 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120850881|UniProtKB=A0ACM8FAZ2 A0ACM8FAZ2 LOC120850881 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC121048139|UniProtKB=A0ACM8FHT1 A0ACM8FHT1 LOC121048139 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;macromolecule localization#GO:0033036;lipid localization#GO:0010876;establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8030148|UniProtKB=A0ACM8EPU5 A0ACM8EPU5 LOC8030148 PTHR46708:SF2 TENASCIN FIBRONECTIN-LIKE extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8023943|UniProtKB=A0ACM8E0Y2 A0ACM8E0Y2 Sgf11 PTHR46367:SF1 ATAXIN-7-LIKE PROTEIN 3 ATAXIN-7-LIKE PROTEIN 3 transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SAGA-type complex#GO:0070461;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;SAGA complex#GO:0000124;DUBm complex#GO:0071819;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 IXOSC|EnsemblGenome=LOC115314950|UniProtKB=A0ACM8DUN2 A0ACM8DUN2 LOC115314950 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8039043|UniProtKB=A0ACM8DK78 A0ACM8DK78 LOC8039043 PTHR12630:SF6 N-LINKED OLIGOSACCHARIDE PROCESSING N-ACETYLGLUCOSAMINE-1-PHOSPHOTRANSFERASE SUBUNIT GAMMA glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115308237|UniProtKB=A0ACM8FPS5 A0ACM8FPS5 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8041723|UniProtKB=A0ACM8E3V2 A0ACM8E3V2 LOC8041723 PTHR22775:SF44 SORTING NEXIN SORTING NEXIN-14 binding#GO:0005488;anion binding#GO:0043168;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular component disassembly#GO:0022411;cellular component organization or biogenesis#GO:0071840;process utilizing autophagic mechanism#GO:0061919;protein-containing complex organization#GO:0043933;autophagosome maturation#GO:0097352;metabolic process#GO:0008152;catabolic process#GO:0009056;macroautophagy#GO:0016236;protein-containing complex disassembly#GO:0032984;cellular component organization#GO:0016043;cellular process#GO:0009987;autophagy#GO:0006914 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115332177|UniProtKB=A0ACM8EZS6 A0ACM8EZS6 LOC115332177 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8038998|UniProtKB=A0ACM8DK98 A0ACM8DK98 LOC8038998 PTHR11022:SF80 PEPTIDOGLYCAN RECOGNITION PROTEIN PEPTIDOGLYCAN-RECOGNITION PROTEIN LC-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;pattern recognition receptor activity#GO:0038187;molecular transducer activity#GO:0060089;hydrolase activity#GO:0016787;peptidoglycan muralytic activity#GO:0061783;N-acetylmuramoyl-L-alanine amidase activity#GO:0008745;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 immune response#GO:0006955;defense response to Gram-positive bacterium#GO:0050830;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;defense response to bacterium#GO:0042742;immune system process#GO:0002376;response to bacterium#GO:0009617;defense response#GO:0006952;response to external stimulus#GO:0009605 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8031598|UniProtKB=A0ACM8EU82 A0ACM8EU82 LOC8031598 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869;transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120850568|UniProtKB=A0ACM8FA60 A0ACM8FA60 LOC120850568 PTHR21358:SF4 PROTEIN MAELSTROM HOMOLOG PROTEIN MAELSTROM HOMOLOG transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;regulation of transcription by RNA polymerase II#GO:0006357;gamete generation#GO:0007276;negative regulation of metabolic process#GO:0009892;nuclear division#GO:0000280;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;male meiotic nuclear division#GO:0007140;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;cell cycle#GO:0007049;primary metabolic process#GO:0044238;developmental process involved in reproduction#GO:0003006;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;reproductive process#GO:0022414;piRNA processing#GO:0034587;sexual reproduction#GO:0019953;regulation of DNA-templated transcription#GO:0006355;organelle fission#GO:0048285;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;multicellular organismal reproductive process#GO:0048609;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;male gamete generation#GO:0048232;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;spermatogenesis#GO:0007283;regulatory ncRNA-mediated gene silencing#GO:0031047;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;meiotic nuclear division#GO:0140013;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8039371|UniProtKB=A0ACM8DXZ7 A0ACM8DXZ7 LOC8039371 PTHR46389:SF3 POLYCOMB GROUP PROTEIN PC POLYCOMB GROUP PROTEIN PC chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115319501|UniProtKB=A0ACM8F1Y0 A0ACM8F1Y0 PTHR10579:SF178 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-LIKE ion channel#PC00133 IXOSC|EnsemblGenome=LOC8041876|UniProtKB=A0ACM8DS68 A0ACM8DS68 LOC8041876 PTHR14304:SF11 CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8029488|UniProtKB=A0ACM8FNU7 A0ACM8FNU7 LOC8029488 PTHR11850:SF266 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN HOMOTHORAX DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of cell population proliferation#GO:0042127;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;pattern specification process#GO:0007389;animal organ morphogenesis#GO:0009887;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;visual system development#GO:0150063;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;eye development#GO:0001654;animal gross anatomical part developmental process#GO:0160108;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of cell population proliferation#GO:0008284;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;animal organ development#GO:0048513;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;embryo development#GO:0009790;sensory system development#GO:0048880;embryonic pattern specification#GO:0009880;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8053428|UniProtKB=A0ACM8E444 A0ACM8E444 beag PTHR12765:SF5 RED PROTEIN IK FACTOR CYTOKINE IK PROTEIN RED gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 cytokine#PC00083 IXOSC|EnsemblGenome=LOC121837391|UniProtKB=A0ACM8G4G7 A0ACM8G4G7 LOC121837391 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8024935|UniProtKB=A0ACM8FJ26 A0ACM8FJ26 LOC8024935 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121834806|UniProtKB=A0ACM8FS74 A0ACM8FS74 LOC121834806 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364 small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;glutathione metabolic process#GO:0006749;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 isomerase#PC00135 IXOSC|EnsemblGenome=LOC8051954|UniProtKB=A0ACM8DWD7 A0ACM8DWD7 Mo25 PTHR10182:SF3 CALCIUM-BINDING PROTEIN 39-RELATED PROTEIN MO25 molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase regulator activity#GO:0019887;protein kinase activator activity#GO:0030295;protein serine/threonine kinase activator activity#GO:0043539;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209 IXOSC|EnsemblGenome=LOC8026111|UniProtKB=A0ACM8G7I0 A0ACM8G7I0 LOC8026111 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121837289|UniProtKB=A0ACM8G428 A0ACM8G428 LOC121837289 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8052039|UniProtKB=A0ACM8EDP3 A0ACM8EDP3 LOC8052039 PTHR12385:SF12 CHOLINE TRANSPORTER-LIKE (SLC FAMILY 44) CHOLINE TRANSPORTER-LIKE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115308496|UniProtKB=A0ACM8EG47 A0ACM8EG47 LOC115308496 PTHR10414:SF78 ETHANOLAMINEPHOSPHOTRANSFERASE DIACYLGLYCEROL CHOLINEPHOSPHOTRANSFERASE transferase#PC00220 IXOSC|EnsemblGenome=LOC121047868|UniProtKB=A0ACM8FFQ1 A0ACM8FFQ1 LOC121047868 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8039581|UniProtKB=A0ACM8EYA6 A0ACM8EYA6 PTHR45920:SF7 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FORMIN-G cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435 IXOSC|EnsemblGenome=LOC8027960|UniProtKB=A0ACM8ETE4 A0ACM8ETE4 LOC8027960 PTHR12753:SF6 AD-003 - RELATED ALPHA N-TERMINAL PROTEIN METHYLTRANSFERASE 1 protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8039941|UniProtKB=A0ACM8DZC3 A0ACM8DZC3 LOC8039941 PTHR12674:SF2 PREFOLDIN SUBUNIT 5 PREFOLDIN SUBUNIT 5 cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8038810|UniProtKB=A0ACM8G1Y6 A0ACM8G1Y6 LOC8038810 PTHR31743:SF1 TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN TCPC4AP SHORT TRANSIENT RECEPTOR POTENTIAL CHANNEL 4-ASSOCIATED PROTEIN protein binding#GO:0005515;phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115309593|UniProtKB=A0ACM8EWP8 A0ACM8EWP8 LOC115309593 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8026626|UniProtKB=A0ACM8FHU3 A0ACM8FHU3 LOC8026626 PTHR47968:SF82 CENTROMERE PROTEIN E KINESIN-LIKE PROTEIN KIN-8B IXOSC|EnsemblGenome=LOC8032636|UniProtKB=A0ACM8E6H6 A0ACM8E6H6 deltaCOP PTHR10121:SF0 COATOMER SUBUNIT DELTA COATOMER SUBUNIT DELTA structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;organelle localization#GO:0051640;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890 cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;membrane coat#GO:0030117;coated membrane#GO:0048475;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;COPI-coated vesicle#GO:0030137;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798 membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC8040892|UniProtKB=A0ACM8EXF6 A0ACM8EXF6 stan PTHR24026:SF51 FAT ATYPICAL CADHERIN-RELATED PROTOCADHERIN-LIKE WING POLARITY PROTEIN STAN neurogenesis#GO:0022008;cell projection morphogenesis#GO:0048858;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;axon development#GO:0061564;neuron projection development#GO:0031175;axonogenesis#GO:0007409;neuron development#GO:0048666;system development#GO:0048731;anatomical structure development#GO:0048856;cell adhesion#GO:0007155;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;cell development#GO:0048468;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;adherens junction#GO:0005912;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 IXOSC|EnsemblGenome=LOC8026769|UniProtKB=A0ACM8FE73 A0ACM8FE73 LOC8026769 PTHR16779:SF1 BETA-1,4-MANNOSYLTRANSFERASE EGH GLYCOLIPID BETA-1,4-MANNOSYLTRANSFERASE EGH hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8051351|UniProtKB=A0ACM8FTC9 A0ACM8FTC9 LOC8051351 PTHR43826:SF3 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 organophosphate ester transmembrane transporter activity#GO:0015605;carbohydrate derivative transmembrane transporter activity#GO:1901505;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748;transport#GO:0006810;inorganic anion transport#GO:0015698;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121833421|UniProtKB=A0ACM8FKY5 A0ACM8FKY5 LOC121833421 PTHR28589:SF1 28S RIBOSOMAL PROTEIN S34, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS34 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8042426|UniProtKB=A0ACM8ECT7 A0ACM8ECT7 Tak1 PTHR46716:SF1 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7 MAP kinase kinase kinase activity#GO:0004709;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 positive regulation of signaling#GO:0023056;MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of intracellular signal transduction#GO:1902531;immune system process#GO:0002376;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;JNK cascade#GO:0007254;positive regulation of response to stimulus#GO:0048584;intracellular signaling cassette#GO:0141124;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;immune response#GO:0006955;signal transduction#GO:0007165 non-receptor serine/threonine protein kinase#PC00167 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>MEK#P00864;TGF-beta signaling pathway#P00052>TAK#P01285;Interleukin signaling pathway#P00036>MEK#P00984;Gonadotropin-releasing hormone receptor pathway#P06664>MAP3Ks#P06834;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442;Gonadotropin-releasing hormone receptor pathway#P06664>TAK1#P06799;p38 MAPK pathway#P05918>TAK1#P06037;Toll receptor signaling pathway#P00054>TAK1#P01370 IXOSC|EnsemblGenome=LOC115326229|UniProtKB=A0ACM8EVR4 A0ACM8EVR4 LOC115326229 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8030216|UniProtKB=A0ACM8G3U8 A0ACM8G3U8 LOC8030216 PTHR24345:SF99 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cytoskeleton organization#GO:0007010 intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;microtubule organizing center#GO:0005815;spindle#GO:0005819;centrosome#GO:0005813;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8038697|UniProtKB=A0ACM8DK93 A0ACM8DK93 Wdr82 PTHR19861:SF0 WD40 REPEAT PROTEIN SWD2 WD REPEAT-CONTAINING PROTEIN 82 chromatin binding#GO:0003682;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;methyltransferase complex#GO:0034708;organelle#GO:0043226;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;Set1C/COMPASS complex#GO:0048188;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120838744|UniProtKB=A0ACM8EJT8 A0ACM8EJT8 LOC120838744 PTHR44566:SF1 TRANSDUCIN/WD40 REPEAT-LIKE SUPERFAMILY PROTEIN WD REPEAT-CONTAINING PROTEIN 25 IXOSC|EnsemblGenome=LOC8037867|UniProtKB=A0ACM8DIA9 A0ACM8DIA9 LOC8037867 PTHR11618:SF4 TRANSCRIPTION INITIATION FACTOR IIB-RELATED TRANSCRIPTION FACTOR IIIB 90 KDA SUBUNIT sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383;DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 general transcription factor#PC00259 Transcription regulation by bZIP transcription factor#P00055>TFIIB#P01397;General transcription regulation#P00023>TFIIB#P00668 IXOSC|EnsemblGenome=LOC8023592|UniProtKB=A0ACM8ECH0 A0ACM8ECH0 LOC8023592 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC121835131|UniProtKB=A0ACM8FSG6 A0ACM8FSG6 LOC121835131 PTHR46809:SF2 STROMAL CELL-DERIVED FACTOR 2-LIKE PROTEIN GH21273P IXOSC|EnsemblGenome=LOC8037059|UniProtKB=A0ACM8DQV0 A0ACM8DQV0 LOC8037059 PTHR15830:SF10 TELOMERE LENGTH REGULATION PROTEIN TEL2 FAMILY MEMBER TELOMERE LENGTH REGULATION PROTEIN TEL2 HOMOLOG telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;heat shock protein binding#GO:0031072;DNA binding#GO:0003677;protein binding#GO:0005515;binding#GO:0005488;nucleic acid binding#GO:0003676;Hsp90 protein binding#GO:0051879 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC121047736|UniProtKB=A0ACM8FHM9 A0ACM8FHM9 LOC121047736 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8037002|UniProtKB=A0ACM8DHV1 A0ACM8DHV1 LOC8037002 PTHR42643:SF49 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8029585|UniProtKB=A0ACM8DIF5 A0ACM8DIF5 LOC8029585 PTHR24241:SF200 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE SIFAMIDE RECEPTOR molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121048705|UniProtKB=A0ACM8G5J8 A0ACM8G5J8 LOC121048705 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8026021|UniProtKB=A0ACM8FZ72 A0ACM8FZ72 LOC8026021 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE alpha-glucosidase activity#GO:0090599;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC121838123|UniProtKB=A0ACM8G6U0 A0ACM8G6U0 LOC121838123 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115314064|UniProtKB=A0ACM8F5F2 A0ACM8F5F2 LOC115314064 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8032582|UniProtKB=A0ACM8ELF6 A0ACM8ELF6 LOC8032582 PTHR43238:SF1 GDP-L-FUCOSE SYNTHASE GDP-L-FUCOSE SYNTHASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120844289|UniProtKB=A0ACM8EYB4 A0ACM8EYB4 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026964|UniProtKB=A0ACM8ES44 A0ACM8ES44 Rab26 PTHR47978:SF21 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-26 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094 regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion#GO:0051046;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8050659|UniProtKB=A0ACM8G8K5 A0ACM8G8K5 LOC8050659 PTHR45620:SF15 PDF RECEPTOR-LIKE PROTEIN-RELATED DIURETIC HORMONE RECEPTOR binding#GO:0005488;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;hormone binding#GO:0042562;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120849398|UniProtKB=A0ACM8F7N4 A0ACM8F7N4 LOC120849398 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8053036|UniProtKB=A0ACM8EWI2 A0ACM8EWI2 LOC8053036 PTHR14383:SF8 SWAP-70 RECOMBINASE PH DOMAIN-CONTAINING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 biological regulation#GO:0065007;signaling#GO:0023052;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;actin cytoskeleton#GO:0015629;nucleus#GO:0005634;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115315901|UniProtKB=A0ACM8F2B5 A0ACM8F2B5 LOC115315901 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8032080|UniProtKB=A0ACM8E5F6 A0ACM8E5F6 kin17 PTHR12805:SF0 KIN17 KIN, ANTIGENIC DETERMINANT OF RECA PROTEIN HOMOLOG DNA_RNA-BINDING PROTEIN KIN17 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular response to stress#GO:0033554;DNA damage response#GO:0006974;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stress#GO:0006950;response to stimulus#GO:0050896 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8044005|UniProtKB=A0ACM8FR75 A0ACM8FR75 ProRS-m PTHR42753:SF10 MITOCHONDRIAL RIBOSOME PROTEIN L39/PROLYL-TRNA LIGASE FAMILY MEMBER PROLINE--TRNA LIGASE, MITOCHONDRIAL-RELATED ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120844858|UniProtKB=A0ACM8EZZ5 A0ACM8EZZ5 LOC120844858 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8051897|UniProtKB=A0ACM8DLX5 A0ACM8DLX5 LOC8051897 PTHR43066:SF1 RHOMBOID-RELATED PROTEIN RHOMBOID-RELATED PROTEIN 4 catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 serine protease#PC00203;protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120839932|UniProtKB=A0ACM8EMU5 A0ACM8EMU5 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115320704|UniProtKB=A0ACM8ETL9 A0ACM8ETL9 LOC115320704 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8040547|UniProtKB=A0ACM8DX92 A0ACM8DX92 LOC8040547 PTHR13773:SF8 PHOSPHATIDATE CYTIDYLYLTRANSFERASE PHOSPHATIDATE CYTIDYLYLTRANSFERASE, PHOTORECEPTOR-SPECIFIC transferase#PC00220 IXOSC|EnsemblGenome=LOC115323886|UniProtKB=A0ACM8EVV7 A0ACM8EVV7 LOC115323886 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8040209|UniProtKB=A0ACM8FJ70 A0ACM8FJ70 LOC8040209 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8031319|UniProtKB=A0ACM8DI57 A0ACM8DI57 LOC8031319 PTHR28621:SF1 SELENOPROTEIN S SELENOPROTEIN S signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;protein transport#GO:0015031;response to unfolded protein#GO:0006986;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;establishment of protein localization#GO:0045184;signal transduction#GO:0007165;response to stress#GO:0006950;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;localization#GO:0051179;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 IXOSC|EnsemblGenome=LOC8033659|UniProtKB=A0ACM8DU82 A0ACM8DU82 Aldh7A1 PTHR43521:SF9 ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;nucleus#GO:0005634;cell periphery#GO:0071944;membrane#GO:0016020;cytosol#GO:0005829 dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC115324411|UniProtKB=A0ACM8FFQ8 A0ACM8FFQ8 LOC115324411 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120840366|UniProtKB=A0ACM8EPA3 A0ACM8EPA3 LOC120840366 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053185|UniProtKB=A0ACM8E9P0 A0ACM8E9P0 LOC8053185 PTHR12591:SF0 GLUCOSE-6-PHOSPHATASE FI19814P1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;sugar-phosphatase activity#GO:0050308;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;glucose metabolic process#GO:0006006;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987;gluconeogenesis#GO:0006094;hexose biosynthetic process#GO:0019319;small molecule metabolic process#GO:0044281;carbohydrate biosynthetic process#GO:0016051;monosaccharide biosynthetic process#GO:0046364;carbohydrate metabolic process#GO:0005975;biosynthetic process#GO:0009058 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120841905|UniProtKB=A0ACM8ETR9 A0ACM8ETR9 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121046207|UniProtKB=A0ACM8FJX4 A0ACM8FJX4 LOC121046207 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121837823|UniProtKB=A0ACM8G6C1 A0ACM8G6C1 LOC121837823 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8023625|UniProtKB=A0ACM8EPC8 A0ACM8EPC8 LOC8023625 PTHR13371:SF0 GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN CENTROSOMAL PROTEIN OF 104 KDA cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 IXOSC|EnsemblGenome=LOC121838211|UniProtKB=A0ACM8G8H4 A0ACM8G8H4 LOC121838211 PTHR45913:SF23 EPM2A-INTERACTING PROTEIN 1 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115313332|UniProtKB=A0ACM8DT11 A0ACM8DT11 Etf-QO PTHR10617:SF107 ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE, MITOCHONDRIAL catalytic activity#GO:0003824;electron transfer activity#GO:0009055;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;electron transport chain#GO:0022900;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8039076|UniProtKB=A0ACM8FY82 A0ACM8FY82 LOC8039076 PTHR11177:SF144 CHITINASE CHITINASE catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC121047600|UniProtKB=A0ACM8FHF3 A0ACM8FHF3 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846821|UniProtKB=A0ACM8FG74 A0ACM8FG74 Ziz PTHR23317:SF26 DEDICATOR OF CYTOKINESIS DOCK ZIZIMIN, ISOFORM K molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;guanyl-nucleotide exchange factor activity#GO:0005085 regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8037538|UniProtKB=A0ACM8DZE7 A0ACM8DZE7 PTHR23255:SF109 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein binding#GO:0005515;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;signaling receptor activity#GO:0038023 cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;regionalization#GO:0003002;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;pattern specification process#GO:0007389;anatomical structure development#GO:0048856;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;dorsal/ventral pattern formation#GO:0009953;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;response to growth factor#GO:0070848;signaling#GO:0023052 signaling receptor complex#GO:0043235;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 serine/threonine protein kinase receptor#PC00205 BMP/activin signaling pathway-drosophila#P06211>TGFbetaR I#P06241;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;GBB signaling pathway#P06214>SAX#P06307;SCW signaling pathway#P06216>SAX#P06329;DPP-SCW signaling pathway#P06212>SAX#P06274;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278 IXOSC|EnsemblGenome=LOC8040396|UniProtKB=A0ACM8EAK1 A0ACM8EAK1 Arp5 PTHR11937:SF16 ACTIN ACTIN-RELATED PROTEIN 5 molecular function regulator activity#GO:0098772;structural molecule activity#GO:0005198;enzyme regulator activity#GO:0030234;structural constituent of cytoskeleton#GO:0005200 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;Ino80 complex#GO:0031011;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232 actin and actin related protein#PC00039 IXOSC|EnsemblGenome=LOC120843476|UniProtKB=A0ACM8EXB7 A0ACM8EXB7 LOC120843476 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;peptidase activity#GO:0008233 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120836085|UniProtKB=A0ACM8ES01 A0ACM8ES01 LOC120836085 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115317963|UniProtKB=A0ACM8EPD8 A0ACM8EPD8 LOC115317963 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120836235|UniProtKB=A0ACM8FPD8 A0ACM8FPD8 LOC121838076 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8042060|UniProtKB=A0ACM8E528 A0ACM8E528 LOC8042060 PTHR11071:SF594 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8036450|UniProtKB=A0ACM8DWP5 A0ACM8DWP5 LOC8036450 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8042063|UniProtKB=A0ACM8FY03 A0ACM8FY03 Eph PTHR24416:SF539 TYROSINE-PROTEIN KINASE RECEPTOR RECEPTOR PROTEIN-TYROSINE KINASE catalytic activity, acting on a protein#GO:0140096;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;protein kinase activity#GO:0004672;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120838558|UniProtKB=A0ACM8FWN5 A0ACM8FWN5 LOC120838558 PTHR44394:SF1 BETA-ALANINE-ACTIVATING ENZYME BETA-ALANINE-ACTIVATING ENZYME ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120847051|UniProtKB=A0ACM8F3W6 A0ACM8F3W6 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115330917|UniProtKB=A0ACM8EBW8 A0ACM8EBW8 LOC115330917 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC120842253|UniProtKB=A0ACM8ETD5 A0ACM8ETD5 LOC120842253 PTHR22896:SF0 CDK5 AND ABL1 ENZYME SUBSTRATE 1 CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041878|UniProtKB=A0ACM8DKT4 A0ACM8DKT4 LOC8041878 PTHR11759:SF1 40S RIBOSOMAL PROTEIN S14/30S RIBOSOMAL PROTEIN S11 SMALL RIBOSOMAL SUBUNIT PROTEIN US11 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;ribonucleoprotein complex biogenesis#GO:0022613;membraneless organelle assembly#GO:0140694;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein metabolic process#GO:0019538;protein-RNA complex assembly#GO:0022618;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;translation#GO:0006412;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;ribosomal small subunit assembly#GO:0000028;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120836308|UniProtKB=A0ACM8EN41 A0ACM8EN41 LOC120836308 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8035158|UniProtKB=A0ACM8EEH6 A0ACM8EEH6 mip40 PTHR31336:SF3 LIN37 HOMOLOG PROTEIN LIN-37 HOMOLOG negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8050417|UniProtKB=A0ACM8E3M0 A0ACM8E3M0 LOC8050417 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115323597|UniProtKB=A0ACM8FBG8 A0ACM8FBG8 LOC115323597 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843810|UniProtKB=A0ACM8G3V1 A0ACM8G3V1 LOC120843810 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121834158|UniProtKB=A0ACM8FMX5 A0ACM8FMX5 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC115320126|UniProtKB=A0ACM8E014 A0ACM8E014 LOC115320126 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039358|UniProtKB=A0ACM8G6M0 A0ACM8G6M0 LOC8039358 PTHR48012:SF16 STERILE20-LIKE KINASE, ISOFORM B-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 response to chemical#GO:0042221;biological regulation#GO:0065007;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to chemical stress#GO:0062197;cellular response to abiotic stimulus#GO:0071214;response to osmotic stress#GO:0006970;response to stimulus#GO:0050896;cellular response to environmental stimulus#GO:0104004;regulation of cellular process#GO:0050794;hyperosmotic response#GO:0006972;signaling#GO:0023052;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to chemical stimulus#GO:0070887;cellular response to osmotic stress#GO:0071470;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8052550|UniProtKB=A0ACM8DND2 A0ACM8DND2 Dus1 PTHR11082:SF5 TRNA-DIHYDROURIDINE SYNTHASE TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8037655|UniProtKB=A0ACM8EXS0 A0ACM8EXS0 LOC8037655 PTHR24068:SF135 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 J2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 ERAD pathway#GO:0036503;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;response to endoplasmic reticulum stress#GO:0034976;protein modification by small protein conjugation or removal#GO:0070647;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;response to chemical#GO:0042221;cellular process#GO:0009987;response to stress#GO:0006950 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 Parkinson disease#P00049>Ubc6#P01222 IXOSC|EnsemblGenome=LOC120847436|UniProtKB=A0ACM8FNF3 A0ACM8FNF3 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833950|UniProtKB=A0ACM8FNW4 A0ACM8FNW4 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC8041802|UniProtKB=A0ACM8ESE5 A0ACM8ESE5 LOC8041802 PTHR11243:SF39 GROWTH FACTOR RECEPTOR-BOUND PROTEIN LD06925P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 cell projection morphogenesis#GO:0048858;cellular component organization or biogenesis#GO:0071840;developmental process#GO:0032502;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;anatomical structure development#GO:0048856;signaling#GO:0023052;response to stimulus#GO:0050896;cell projection organization#GO:0030030;regulation of cellular process#GO:0050794;cell morphogenesis#GO:0000902;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8052156|UniProtKB=A0ACM8DNH4 A0ACM8DNH4 crc PTHR13044:SF14 ACTIVATING TRANSCRIPTION FACTOR ATF 4/5 CRYPTOCEPHAL, ISOFORM A DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8052975|UniProtKB=A0ACM8EC10 A0ACM8EC10 LOC8052975 PTHR10024:SF378 SYNAPTOTAGMIN SYNAPTOTAGMIN BETA, ISOFORM D phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149;protein binding#GO:0005515;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772 transport#GO:0006810;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of localization#GO:0032879;regulation of transport#GO:0051049;establishment of localization#GO:0051234;regulation of secretion#GO:0051046;localization#GO:0051179;cellular process#GO:0009987;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;transport vesicle#GO:0030133;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;secretory vesicle#GO:0099503;cell periphery#GO:0071944 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC120835940|UniProtKB=A0ACM8FXF3 A0ACM8FXF3 LOC120835940 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8026863|UniProtKB=A0ACM8DIG1 A0ACM8DIG1 LOC8026863 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;binding#GO:0005488;small molecule binding#GO:0036094 fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8031525|UniProtKB=A0ACM8EE04 A0ACM8EE04 LOC8031525 PTHR44899:SF11 CAMK FAMILY PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8030459|UniProtKB=A0ACM8EAW3 A0ACM8EAW3 LOC8030459 PTHR10649:SF12 ARYL HYDROCARBON RECEPTOR SPINELESS, ISOFORM C DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;signaling receptor complex#GO:0043235;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115324541|UniProtKB=A0ACM8F1N7 A0ACM8F1N7 LOC115324541 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318482|UniProtKB=A0ACM8F3S4 A0ACM8F3S4 LOC115318482 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120842905|UniProtKB=A0ACM8EVZ7 A0ACM8EVZ7 LOC120842905 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8038587|UniProtKB=A0ACM8E1C0 A0ACM8E1C0 LOC8038587 PTHR45712:SF22 AGAP008170-PA LEUCINE RICH REPEAT TRANSMEMBRANE NEURONAL 4 IXOSC|EnsemblGenome=LOC120851165|UniProtKB=A0ACM8FCA1 A0ACM8FCA1 LOC120851165 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8031173|UniProtKB=A0ACM8E8Y1 A0ACM8E8Y1 LOC8031173 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8036374|UniProtKB=A0ACM8DJV8 A0ACM8DJV8 ClpP PTHR10381:SF11 ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT, MITOCHONDRIAL protein binding#GO:0005515;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;binding#GO:0005488;ATP-dependent activity#GO:0140657;enzyme binding#GO:0019899;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056 protein-containing complex#GO:0032991;catalytic complex#GO:1902494 serine protease#PC00203 IXOSC|EnsemblGenome=LOC121048257|UniProtKB=A0ACM8G2B3 A0ACM8G2B3 LOC121048257 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8051444|UniProtKB=A0ACM8DNX3 A0ACM8DNX3 LOC8051444 PTHR24377:SF1046 IP01015P-RELATED FI01202P-RELATED C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8027876|UniProtKB=A0ACM8E3Z7 A0ACM8E3Z7 Hpr1 PTHR13265:SF0 THO COMPLEX SUBUNIT 1 HPR1 establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transcription export complex#GO:0000346;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115314621|UniProtKB=A0ACM8FYB3 A0ACM8FYB3 LOC115314621 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115332453|UniProtKB=A0ACM8EL83 A0ACM8EL83 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026633|UniProtKB=A0ACM8FK12 A0ACM8FK12 LOC8026633 PTHR43564:SF2 KYNURENINE FORMAMIDASE-LIKE PROTEIN BLR6059 PROTEIN IXOSC|EnsemblGenome=LOC115314901|UniProtKB=A0ACM8FI07 A0ACM8FI07 LOC115314901 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120838516|UniProtKB=A0ACM8FKF2 A0ACM8FKF2 LOC120838516 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053242|UniProtKB=A0ACM8DGW9 A0ACM8DGW9 LOC8053242 PTHR12131:SF31 ATP-DEPENDENT RNA AND DNA HELICASE ATP-DEPENDENT RNA HELICASE SUPV3L1, MITOCHONDRIAL nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mitochondrial RNA 3'-end processing#GO:0000965;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8051586|UniProtKB=A0ACM8ERW6 A0ACM8ERW6 LOC8051586 PTHR31919:SF1 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 ZINC FINGERS AND HOMEOBOXES PROTEIN 1, ISOFORM 2 homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8023853|UniProtKB=A0ACM8EE10 A0ACM8EE10 LOC8023853 PTHR19878:SF19 AUTOPHAGY PROTEIN 16-LIKE AUTOPHAGY-RELATED 16, ISOFORM F protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular component assembly#GO:0022607;metabolic process#GO:0008152;organelle assembly#GO:0070925;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;autophagosome assembly#GO:0000045;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;autophagosome#GO:0005776;vacuole#GO:0005773;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;transferase complex#GO:1990234;phagophore assembly site#GO:0000407 IXOSC|EnsemblGenome=LOC121835546|UniProtKB=A0ACM8FVH0 A0ACM8FVH0 LOC121835546 PTHR11733:SF252 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-LIKE 4 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8025724|UniProtKB=A0ACM8F7Z4 A0ACM8F7Z4 LOC8025724 PTHR46392:SF1 DUAL SERINE/THREONINE AND TYROSINE PROTEIN KINASE DUAL SERINE_THREONINE AND TYROSINE PROTEIN KINASE positive regulation of cellular process#GO:0048522;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;negative regulation of apoptotic process#GO:0043066;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;response to fibroblast growth factor#GO:0071774;negative regulation of cellular process#GO:0048523;positive regulation of MAPK cascade#GO:0043410;positive regulation of signal transduction#GO:0009967;positive regulation of ERK1 and ERK2 cascade#GO:0070374;regulation of cell communication#GO:0010646;response to growth factor#GO:0070848;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;cellular response to fibroblast growth factor stimulus#GO:0044344;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;regulation of ERK1 and ERK2 cascade#GO:0070372;regulation of MAPK cascade#GO:0043408;regulation of apoptotic process#GO:0042981;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;cellular response to growth factor stimulus#GO:0071363;positive regulation of signaling#GO:0023056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8033031|UniProtKB=A0ACM8FK81 A0ACM8FK81 LOC8033031 PTHR10527:SF6 IMPORTIN BETA IMPORTIN-4 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 transporter#PC00227 IXOSC|EnsemblGenome=LOC8031988|UniProtKB=A0ACM8E020 A0ACM8E020 LOC8031988 PTHR46556:SF1 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2 cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein binding#GO:0005515 endomembrane system organization#GO:0010256;biological regulation#GO:0065007;regulation of biological process#GO:0050789;Golgi organization#GO:0007030;cellular process#GO:0009987;lysosome localization#GO:0032418;organelle organization#GO:0006996;cellular component organization#GO:0016043;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle localization#GO:0051640 intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120850581|UniProtKB=A0ACM8G516 A0ACM8G516 LOC120850581 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029229|UniProtKB=A0ACM8G156 A0ACM8G156 LOC8029229 PTHR43564:SF2 KYNURENINE FORMAMIDASE-LIKE PROTEIN BLR6059 PROTEIN IXOSC|EnsemblGenome=LOC120841255|UniProtKB=A0ACM8ERE9 A0ACM8ERE9 LOC120841255 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8036189|UniProtKB=A0ACM8DJU4 A0ACM8DJU4 SmD2 PTHR12777:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 SMALL NUCLEAR RIBONUCLEOPROTEIN SM D2 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398 small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;cytoplasm#GO:0005737;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;catalytic step 2 spliceosome#GO:0071013;spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC115324546|UniProtKB=A0ACM8EWN2 A0ACM8EWN2 LOC115324546 PTHR43963:SF4 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE (NADPH) oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115308335|UniProtKB=A0ACM8G5K0 A0ACM8G5K0 LOC115308335 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120847452|UniProtKB=A0ACM8F3X3 A0ACM8F3X3 LOC120847452 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;localization#GO:0051179;establishment of localization#GO:0051234 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120838181|UniProtKB=A0ACM8EIQ2 A0ACM8EIQ2 Bcat PTHR11825:SF44 SUBGROUP IIII AMINOTRANSFERASE BRANCHED-CHAIN-AMINO-ACID AMINOTRANSFERASE transaminase activity#GO:0008483;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transaminase#PC00216;transferase#PC00220 Valine biosynthesis#P02785>Branched chain amino acid aminotransferase#P03215;Isoleucine biosynthesis#P02748>Branched chain amino acid aminotransferase#P02994;Alanine biosynthesis#P02724>Branched chain amino acid aminotransferase#P02815;Leucine biosynthesis#P02749>Branched chain amino acid aminotransferase#P03000 IXOSC|EnsemblGenome=LOC115323048|UniProtKB=A0ACM8G3B0 A0ACM8G3B0 LOC115323048 PTHR11532:SF57 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE E catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180 primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 IXOSC|EnsemblGenome=LOC115322743|UniProtKB=A0ACM8E386 A0ACM8E386 LOC115322743 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC115327927|UniProtKB=A0ACM8FEX5 A0ACM8FEX5 PTHR19303:SF78 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052243|UniProtKB=A0ACM8EAB8 A0ACM8EAB8 LOC8052243 PTHR15414:SF0 OS-9-RELATED ENDOPLASMIC RETICULUM LECTIN 1 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;cellular localization#GO:0051641;response to unfolded protein#GO:0006986;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to topologically incorrect protein#GO:0035966;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule localization#GO:0033036;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;localization#GO:0051179;cellular response to topologically incorrect protein#GO:0035967;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 IXOSC|EnsemblGenome=LOC115320481|UniProtKB=A0ACM8EMU1 A0ACM8EMU1 LOC115320481 PTHR18978:SF1 GRIP-1 ASSOCIATED PROTEIN 1 GRIP1-ASSOCIATED PROTEIN 1 regulation of protein localization to membrane#GO:1905475;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;regulation of protein transport#GO:0051223;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of transport#GO:0051049;regulation of biological quality#GO:0065008 membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;presynapse#GO:0098793;glutamatergic synapse#GO:0098978;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;early endosome membrane#GO:0031901;cell junction#GO:0030054;extrinsic component of membrane#GO:0019898;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;postsynapse#GO:0098794;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC120837988|UniProtKB=A0ACM8EIB0 A0ACM8EIB0 LOC120837988 PTHR22932:SF1 TELOMERASE-BINDING PROTEIN P23 HSP90 CO-CHAPERONE CYTOSOLIC PROSTAGLANDIN E SYNTHASE protein-folding chaperone binding#GO:0051087;binding#GO:0005488;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879;protein binding#GO:0005515 protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein folding#GO:0006457;chaperone-mediated protein complex assembly#GO:0051131;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115313287|UniProtKB=A0ACM8F239 A0ACM8F239 LOC115313287 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8038454|UniProtKB=A0ACM8E467 A0ACM8E467 Gmer PTHR43238:SF1 GDP-L-FUCOSE SYNTHASE GDP-L-FUCOSE SYNTHASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121837190|UniProtKB=A0ACM8G2A9 A0ACM8G2A9 LOC121837190 PTHR43948:SF10 DNAJ HOMOLOG SUBFAMILY B MRJ, ISOFORM E binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120836006|UniProtKB=A0ACM8FG50 A0ACM8FG50 LOC121836416 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC120840711|UniProtKB=A0ACM8EQT9 A0ACM8EQT9 LOC120840711 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115328316|UniProtKB=A0ACM8ES90 A0ACM8ES90 LOC115328316 PTHR28629:SF4 TRIOKINASE/FMN CYCLASE TRIOKINASE_FMN CYCLASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 cyclase#PC00079 IXOSC|EnsemblGenome=LOC8030837|UniProtKB=A0ACM8DHJ9 A0ACM8DHJ9 LOC8030837 PTHR13602:SF2 UPF0488 PROTEIN C8ORF33 UPF0488 PROTEIN C8ORF33 IXOSC|EnsemblGenome=LOC120838515|UniProtKB=A0ACM8EJY5 A0ACM8EJY5 LOC120838515 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120838549|UniProtKB=A0ACM8EK82 A0ACM8EK82 LOC120838549 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029763|UniProtKB=A0ACM8ECU2 A0ACM8ECU2 LOC8029763 PTHR23085:SF16 GH28348P GH28348P plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;sarcoplasm#GO:0016528 IXOSC|EnsemblGenome=LOC120842727|UniProtKB=A0ACM8EVJ4 A0ACM8EVJ4 LOC120842727 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8037132|UniProtKB=A0ACM8DXF9 A0ACM8DXF9 LOC8037132 PTHR22770:SF48 UBIQUITIN CONJUGATING ENZYME 7 INTERACTING PROTEIN-RELATED RANBP-TYPE AND C3HC4-TYPE ZINC FINGER-CONTAINING PROTEIN 1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 proteasomal protein catabolic process#GO:0010498;positive regulation of non-canonical NF-kappaB signal transduction#GO:1901224;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of canonical NF-kappaB signal transduction#GO:0043123;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of non-canonical NF-kappaB signal transduction#GO:1901222;regulation of biological process#GO:0050789;positive regulation of signaling#GO:0023056;regulation of intracellular signal transduction#GO:1902531;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;positive regulation of response to stimulus#GO:0048584;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of cellular process#GO:0048522;regulation of canonical NF-kappaB signal transduction#GO:0043122;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120850861|UniProtKB=A0ACM8F9V0 A0ACM8F9V0 LOC120850861 PTHR31569:SF9 SWIM-TYPE DOMAIN-CONTAINING PROTEIN SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030095|UniProtKB=A0ACM8FN13 A0ACM8FN13 LOC8030095 PTHR46340:SF1 UBX DOMAIN-CONTAINING PROTEIN 1 UBX DOMAIN-CONTAINING PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030 negative regulation of protein ubiquitination#GO:0031397;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of post-translational protein modification#GO:1901873;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of cellular process#GO:0050794;negative regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032435;regulation of macromolecule metabolic process#GO:0060255;regulation of protein ubiquitination#GO:0031396;negative regulation of cellular process#GO:0048523;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of catabolic process#GO:0009894;regulation of protein modification process#GO:0031399;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of protein catabolic process#GO:0042177;regulation of proteasomal protein catabolic process#GO:0061136 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8028494|UniProtKB=A0ACM8E0U3 A0ACM8E0U3 LOC8028494 PTHR13681:SF24 SURVIVAL OF MOTOR NEURON-RELATED-SPLICING FACTOR 30-RELATED TUDOR DOMAIN-CONTAINING PROTEIN 3 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;nucleic acid binding#GO:0003676;binding#GO:0005488;histone reader activity#GO:0140566;RNA binding#GO:0003723;chromatin-protein adaptor activity#GO:0140463 siRNA-mediated heterochromatin formation#GO:0141194;regulatory ncRNA-mediated heterochromatin formation#GO:0031048;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;cellular component assembly#GO:0022607;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC121835418|UniProtKB=A0ACM8FTU3 A0ACM8FTU3 LOC121835418 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052093|UniProtKB=A0ACM8EI42 A0ACM8EI42 LOC8052093 PTHR11566:SF237 DYNAMIN DYNAMIN GTPASE cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activity#GO:0003924;microtubule binding#GO:0008017;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;hydrolase activity#GO:0016787;protein binding#GO:0005515 mitochondrial fission#GO:0000266;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrion localization#GO:0051646;organelle localization#GO:0051640;peroxisome organization#GO:0007031 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8036177|UniProtKB=A0ACM8DW23 A0ACM8DW23 LOC8036177 PTHR10374:SF30 LACTOYLGLUTATHIONE LYASE GLYOXALASE I LACTOYLGLUTATHIONE LYASE metabolite interconversion enzyme#PC00262;lyase#PC00144 IXOSC|EnsemblGenome=LOC8027599|UniProtKB=A0ACM8DJ74 A0ACM8DJ74 PIG-V PTHR12468:SF2 GPI MANNOSYLTRANSFERASE 2 GPI ALPHA-1,6-MANNOSYLTRANSFERASE 2 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;phospholipid metabolic process#GO:0006644;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycolipid biosynthetic process#GO:0009247;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;mannosyltransferase complex#GO:0031501;membrane#GO:0016020;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115311470|UniProtKB=A0ACM8DR32 A0ACM8DR32 LOC115311470 PTHR14790:SF15 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 RMI1 RECQ-MEDIATED GENOME INSTABILITY PROTEIN 1 response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;resolution of meiotic recombination intermediates#GO:0000712;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285 membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;DNA helicase complex#GO:0033202 IXOSC|EnsemblGenome=LOC121833310|UniProtKB=A0ACM8FK38 A0ACM8FK38 LOC121833310 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8052905|UniProtKB=A0ACM8E3N2 A0ACM8E3N2 LOC8052905 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8053467|UniProtKB=A0ACM8DLQ5 A0ACM8DLQ5 LOC8053467 PTHR10010:SF46 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115313516|UniProtKB=A0ACM8DT37 A0ACM8DT37 LOC115313516 PTHR10398:SF2 AFADIN AFADIN cytoskeletal adaptor activity#GO:0008093;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cellular process#GO:0009987;adherens junction organization#GO:0034332;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cell adhesion#GO:0007155;cell-cell junction organization#GO:0045216;cellular component organization or biogenesis#GO:0071840;cell-cell junction maintenance#GO:0045217 cell cortex#GO:0005938;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell junction#GO:0030054 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 Alzheimer disease-presenilin pathway#P00004>Afadin#P00146 IXOSC|EnsemblGenome=LOC115331635|UniProtKB=A0ACM8EYS7 A0ACM8EYS7 LOC115331635 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8029253|UniProtKB=A0ACM8G640 A0ACM8G640 LOC8029253 PTHR24329:SF543 HOMEOBOX PROTEIN ARISTALESS HOMEOBOX PROTEIN CEH-17 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;neuron differentiation#GO:0030182;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8025400|UniProtKB=A0ACM8FMI4 A0ACM8FMI4 PTHR24235:SF29 NEUROPEPTIDE Y RECEPTOR GH23382P signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8039385|UniProtKB=A0ACM8DUG5 A0ACM8DUG5 LOC8039385 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity#GO:0003824;transferase activity#GO:0016740;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;glutathione metabolic process#GO:0006749 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 isomerase#PC00135 IXOSC|EnsemblGenome=LOC8032317|UniProtKB=A0ACM8ED55 A0ACM8ED55 LOC8032317 PTHR31220:SF10 HYCCIN RELATED GH21176P glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;protein localization to membrane#GO:0072657;primary metabolic process#GO:0044238;protein localization to plasma membrane#GO:0072659;phosphorus metabolic process#GO:0006793;localization#GO:0051179;cellular localization#GO:0051641;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;localization within membrane#GO:0051668;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;intracellular protein localization#GO:0008104;metabolic process#GO:0008152;protein localization to cell periphery#GO:1990778;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115324421|UniProtKB=A0ACM8E4T9 A0ACM8E4T9 LOC115324421 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8040183|UniProtKB=A0ACM8E3S4 A0ACM8E3S4 LOC8040183 PTHR10048:SF14 PHOSPHATIDYLINOSITOL KINASE LD28067P phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;cell motility#GO:0048870;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;signal transduction#GO:0007165;organophosphate metabolic process#GO:0019637;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 kinase#PC00137 VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;p53 pathway feedback loops 2#P04398>PI3K#P04661;FGF signaling pathway#P00021>PI3K#P00640;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;Apoptosis signaling pathway#P00006>PI3K#P00310;PDGF signaling pathway#P00047>PI3K#P01168;EGF receptor signaling pathway#P00018>PI3K#P00557;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Angiogenesis#P00005>PI3K#P00236 IXOSC|EnsemblGenome=LOC120839051|UniProtKB=A0ACM8EKL4 A0ACM8EKL4 LOC120839051 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121836109|UniProtKB=A0ACM8FXC4 A0ACM8FXC4 LOC121836109 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121048031|UniProtKB=A0ACM8G6G9 A0ACM8G6G9 LOC121048031 PTHR13306:SF6 TRANSMEMBRANE PROTEIN 138 TRANSMEMBRANE PROTEIN 138 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115316493|UniProtKB=A0ACM8DWG2 A0ACM8DWG2 Srp19 PTHR17453:SF0 SIGNAL RECOGNITION PARTICLE 19 KD PROTEIN SIGNAL RECOGNITION PARTICLE 19 KDA PROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein targeting#GO:0006605;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;protein targeting to ER#GO:0045047;protein targeting to membrane#GO:0006612;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;cellular component assembly#GO:0022607;establishment of protein localization to endoplasmic reticulum#GO:0072599;establishment of protein localization to membrane#GO:0090150;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;establishment of protein localization#GO:0045184 ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8042816|UniProtKB=A0ACM8EMV6 A0ACM8EMV6 LOC8042816 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115316905|UniProtKB=A0ACM8DWF5 A0ACM8DWF5 LOC115316905 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115326276|UniProtKB=A0ACM8E6F3 A0ACM8E6F3 LOC115326276 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8041947|UniProtKB=A0ACM8EVC0 A0ACM8EVC0 LOC8041947 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8042237|UniProtKB=A0ACM8FBA3 A0ACM8FBA3 LOC8042237 PTHR22948:SF29 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8041767|UniProtKB=A0ACM8DNL9 A0ACM8DNL9 eIF3b PTHR14068:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EIF3 -RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120841317|UniProtKB=A0ACM8ESE6 A0ACM8ESE6 LOC120841317 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041760|UniProtKB=A0ACM8FZK8 A0ACM8FZK8 LOC8041760 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC115320641|UniProtKB=A0ACM8E1F1 A0ACM8E1F1 LOC115320641 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314116|UniProtKB=A0ACM8DTX5 A0ACM8DTX5 Cnot4 PTHR12603:SF0 CCR4-NOT TRANSCRIPTION COMPLEX RELATED CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 4 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein transferase activity#GO:0019787 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA stability#GO:0043487;protein metabolic process#GO:0019538;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;protein catabolic process#GO:0030163;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;CCR4-NOT complex#GO:0030014 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8039344|UniProtKB=A0ACM8FS81 A0ACM8FS81 nompA PTHR47327:SF9 FI18240P1-RELATED NO MECHANORECEPTOR POTENTIAL A, ISOFORM A anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856 IXOSC|EnsemblGenome=LOC8039184|UniProtKB=A0ACM8E2V1 A0ACM8E2V1 LOC8039184 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115313870|UniProtKB=A0ACM8FNL8 A0ACM8FNL8 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC120844703|UniProtKB=A0ACM8EZG5 A0ACM8EZG5 LOC120844703 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120838508|UniProtKB=A0ACM8G1V1 A0ACM8G1V1 Ctr1A PTHR12483:SF115 SOLUTE CARRIER FAMILY 31 COPPER TRANSPORTERS COPPER TRANSPORT PROTEIN transition metal ion transmembrane transporter activity#GO:0046915;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 cellular process#GO:0009987;copper ion transmembrane transport#GO:0035434;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC121046946|UniProtKB=A0ACM8FJR0 A0ACM8FJR0 LOC121046946 PTHR11690:SF248 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL ligand-gated monoatomic cation channel activity#GO:0099094;transporter activity#GO:0005215;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 sodium ion transport#GO:0006814;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC121048346|UniProtKB=A0ACM8FGV4 A0ACM8FGV4 LOC121048346 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330463|UniProtKB=A0ACM8F3T9 A0ACM8F3T9 LOC115330463 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8052567|UniProtKB=A0ACM8DGH2 A0ACM8DGH2 LOC8052567 PTHR22776:SF49 MARVEL-CONTAINING POTENTIAL LIPID RAFT-ASSOCIATED PROTEIN MARVEL DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;signaling#GO:0023052;regulation of biological process#GO:0050789 membrane#GO:0016020;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053135|UniProtKB=A0ACM8FH96 A0ACM8FH96 LOC8053135 PTHR46320:SF1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE 1 phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;amine metabolic process#GO:0009308;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;small molecule metabolic process#GO:0044281 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 hydrolase#PC00121;phosphodiesterase#PC00185 IXOSC|EnsemblGenome=LOC8028467|UniProtKB=A0ACM8E7T0 A0ACM8E7T0 LOC8028467 PTHR21199:SF1 COMM DOMAIN-CONTAINING PROTEIN 1 COMM DOMAIN-CONTAINING PROTEIN 1 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 positive regulation of protein metabolic process#GO:0051247;regulation of protein catabolic process#GO:0042176;regulation of post-translational protein modification#GO:1901873;localization#GO:0051179;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of protein ubiquitination#GO:0031396;transport#GO:0006810;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein modification process#GO:0031399;regulation of catabolic process#GO:0009894;establishment of localization#GO:0051234;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of protein ubiquitination#GO:0031398;vesicle-mediated transport#GO:0016192 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8038960|UniProtKB=A0ACM8FTF1 A0ACM8FTF1 LOC8038960 PTHR11804:SF84 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED SACCHAROLYSIN hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115330100|UniProtKB=A0ACM8G3S3 A0ACM8G3S3 LOC115330100 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120838745|UniProtKB=A0ACM8EKD7 A0ACM8EKD7 LOC120838745 PTHR12722:SF0 XAP-5 PROTEIN-RELATED PROTEIN FAM50A chromatin organization#GO:0006325;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8026998|UniProtKB=A0ACM8G178 A0ACM8G178 LOC8026998 PTHR12176:SF78 SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835956|UniProtKB=A0ACM8FWJ2 A0ACM8FWJ2 LOC121835956 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120835995|UniProtKB=A0ACM8G4H7 A0ACM8G4H7 LOC120835995 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115313465|UniProtKB=A0ACM8DT31 A0ACM8DT31 LOC115313465 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115311884|UniProtKB=A0ACM8DRG3 A0ACM8DRG3 LOC115311884 PTHR22950:SF703 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER AVT1J-LIKE L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;amino acid transport#GO:0006865;cellular process#GO:0009987;transport#GO:0006810 vacuolar membrane#GO:0005774;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 amino acid transporter#PC00046;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115326643|UniProtKB=A0ACM8F1P5 A0ACM8F1P5 LOC115326643 PTHR13005:SF4 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115330725|UniProtKB=A0ACM8ECL4 A0ACM8ECL4 LOC115330725 PTHR12327:SF0 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 ALPHA-TUBULIN N-ACETYLTRANSFERASE 1 protein N-acyltransferase activity#GO:0140186;protein-lysine-acetyltransferase activity#GO:0061733;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;N-acetyltransferase activity#GO:0008080;protein N-acetyltransferase activity#GO:0034212;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 IXOSC|EnsemblGenome=LOC8043179|UniProtKB=A0ACM8E4V1 A0ACM8E4V1 LOC8043179 PTHR42850:SF4 METALLOPHOSPHOESTERASE ZINC-DEPENDENT ENDOPOLYPHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC120842083|UniProtKB=A0ACM8ET37 A0ACM8ET37 LOC120842083 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043438|UniProtKB=A0ACM8E116 A0ACM8E116 LOC8043438 PTHR11552:SF233 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI02019P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121833157|UniProtKB=A0ACM8FJQ8 A0ACM8FJQ8 LOC121833157 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8040002|UniProtKB=A0ACM8FXZ9 A0ACM8FXZ9 LOC8040002 PTHR15950:SF15 TRANSCRIPTION COFACTOR VESTIGIAL-LIKE PROTEIN PROTEIN VESTIGIAL-RELATED regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC8036914|UniProtKB=A0ACM8G6U5 A0ACM8G6U5 LOC8036914 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121836600|UniProtKB=A0ACM8FZD7 A0ACM8FZD7 LOC121836600 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845185|UniProtKB=A0ACM8F012 A0ACM8F012 LOC120845185 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053677|UniProtKB=A0ACM8E486 A0ACM8E486 LOC8053677 PTHR19384:SF84 NITRIC OXIDE SYNTHASE-RELATED METHIONINE SYNTHASE REDUCTASE small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;oxidoreductase activity, acting on metal ions#GO:0016722;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367 biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;aspartate family amino acid biosynthetic process#GO:0009067;homocysteine metabolic process#GO:0050667;sulfur compound metabolic process#GO:0006790;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8034578|UniProtKB=A0ACM8EAF2 A0ACM8EAF2 LOC8034578 PTHR48228:SF8 SUCCINYL-COA--D-CITRAMALATE COA-TRANSFERASE ALPHA-METHYLACYL-COA RACEMASE catalytic activity#GO:0003824;racemase and epimerase activity#GO:0016854;isomerase activity#GO:0016853 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;steroid metabolic process#GO:0008202 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 Carnitine metabolism#P02733>Carnitine dehydratase#P02866;Coenzyme A linked carnitine metabolism#P02732>L-carnitine dehydratase#P02864 IXOSC|EnsemblGenome=LOC8024294|UniProtKB=A0ACM8FNY3 A0ACM8FNY3 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8031254|UniProtKB=A0ACM8E9Y8 A0ACM8E9Y8 LOC8031254 PTHR23330:SF10 P300 TRANSCRIPTIONAL COFACTOR JMY-RELATED FIBROUS SHEATH CABYR-BINDING PROTEIN-LIKE cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115326544|UniProtKB=A0ACM8E736 A0ACM8E736 LOC115326544 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8033189|UniProtKB=A0ACM8E726 A0ACM8E726 LOC8033189 PTHR47958:SF215 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC120836911|UniProtKB=A0ACM8EG48 A0ACM8EG48 LOC120836911 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8028246|UniProtKB=A0ACM8DJM1 A0ACM8DJM1 LOC8028246 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120837465|UniProtKB=A0ACM8EIG8 A0ACM8EIG8 LOC120837465 PTHR46173:SF1 CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL CCA TRNA NUCLEOTIDYLTRANSFERASE 1, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA binding#GO:0000049;RNA binding#GO:0003723 RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;mitochondrial RNA 3'-end processing#GO:0000965;tRNA 3'-end processing#GO:0042780;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121048478|UniProtKB=A0ACM8FRA8 A0ACM8FRA8 LOC121048478 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8039444|UniProtKB=A0ACM8E4U4 A0ACM8E4U4 LOC8039444 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC8024492|UniProtKB=A0ACM8E9S8 A0ACM8E9S8 LOC8024492 PTHR46901:SF2 GH04942P GH04942P IXOSC|EnsemblGenome=LOC8042344|UniProtKB=A0ACM8E5J3 A0ACM8E5J3 LOC8042344 PTHR18966:SF607 IONOTROPIC GLUTAMATE RECEPTOR EYE-ENRICHED KAINATE RECEPTOR, ISOFORM B transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794 postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8039325|UniProtKB=A0ACM8DKA4 A0ACM8DKA4 LOC8039325 PTHR12847:SF9 ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED NECAP-LIKE PROTEIN CG9132 coated membrane#GO:0048475;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;intracellular organelle#GO:0043229;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle#GO:0030136;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8028946|UniProtKB=A0ACM8DQP8 A0ACM8DQP8 LOC8028946 PTHR23137:SF6 VESICLE TRANSPORT PROTEIN-RELATED VESICLE TRANSPORT PROTEIN IXOSC|EnsemblGenome=LOC120849123|UniProtKB=A0ACM8F765 A0ACM8F765 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8052223|UniProtKB=A0ACM8EX77 A0ACM8EX77 heix PTHR13929:SF17 1,4-DIHYDROXY-2-NAPHTHOATE OCTAPRENYLTRANSFERASE UBIA PRENYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;ketone metabolic process#GO:0042180;vitamin K metabolic process#GO:0042373;biosynthetic process#GO:0009058;menaquinone biosynthetic process#GO:0009234;small molecule metabolic process#GO:0044281 transferase#PC00220 IXOSC|EnsemblGenome=LOC115317021|UniProtKB=A0ACM8EXA9 A0ACM8EXA9 LOC120840368 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115311158|UniProtKB=A0ACM8F8J9 A0ACM8F8J9 LOC115311158 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8039893|UniProtKB=A0ACM8ESK5 A0ACM8ESK5 Rbm13 PTHR23405:SF4 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED PROTEIN MAK16 HOMOLOG ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC120849318|UniProtKB=A0ACM8F8I9 A0ACM8F8I9 LOC120849318 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024825|UniProtKB=A0ACM8F3Y2 A0ACM8F3Y2 LOC8024825 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC115327228|UniProtKB=A0ACM8E6R4 A0ACM8E6R4 LOC115327228 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8033044|UniProtKB=A0ACM8EAU9 A0ACM8EAU9 PTHR33861:SF5 PROTEIN CBG18333 GAMMA-TUBULIN COMPLEX COMPONENT organelle fission#GO:0048285;positive regulation of biosynthetic process#GO:0009891;multicellular organismal reproductive process#GO:0048609;regulation of RNA metabolic process#GO:0051252;negative regulation of catabolic process#GO:0009895;regulation of RNA stability#GO:0043487;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;reproductive process#GO:0022414;cell cycle#GO:0007049;meiotic nuclear division#GO:0140013;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;positive regulation of gene expression#GO:0010628;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of RNA catabolic process#GO:1902369;male gamete generation#GO:0048232;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;RNA stabilization#GO:0043489;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of biological quality#GO:0065008;nuclear division#GO:0000280;gamete generation#GO:0007276;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;meiosis I#GO:0007127;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;regulation of mRNA metabolic process#GO:1903311;cellular component organization or biogenesis#GO:0071840;meiotic cell cycle#GO:0051321;negative regulation of RNA metabolic process#GO:0051253;positive regulation of macromolecule metabolic process#GO:0010604;male meiotic nuclear division#GO:0007140;mRNA stabilization#GO:0048255;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8040958|UniProtKB=A0ACM8E3V5 A0ACM8E3V5 LOC8040958 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 hydrolase activity#GO:0016787;lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;A2-type glycerophospholipase activity#GO:0004623;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 IXOSC|EnsemblGenome=LOC120844652|UniProtKB=A0ACM8EZ40 A0ACM8EZ40 LOC120844652 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115310771|UniProtKB=A0ACM8ETU8 A0ACM8ETU8 LOC115310771 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120847899|UniProtKB=A0ACM8F4U0 A0ACM8F4U0 LOC120847899 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120843806|UniProtKB=A0ACM8EWW8 A0ACM8EWW8 LOC120843806 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121835229|UniProtKB=A0ACM8FS26 A0ACM8FS26 LOC121835229 PTHR24369:SF222 ANTIGEN BSP, PUTATIVE-RELATED SUBFAMILY NOT NAMED cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC121833547|UniProtKB=A0ACM8FLS3 A0ACM8FLS3 LOC121833547 PTHR12101:SF1 POPEYE DOMAIN CONTAINING PROTEIN BVES ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;striated muscle cell differentiation#GO:0051146;developmental process#GO:0032502;multicellular organismal process#GO:0032501;heart development#GO:0007507;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154;muscle cell differentiation#GO:0042692 apical junction complex#GO:0043296;anchoring junction#GO:0070161;cell junction#GO:0030054;sarcolemma#GO:0042383;tight junction#GO:0070160;cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115313993|UniProtKB=A0ACM8DTR3 A0ACM8DTR3 LOC115313993 PTHR21706:SF15 TRANSMEMBRANE PROTEIN 65 LP09246P intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8023533|UniProtKB=A0ACM8EDL5 A0ACM8EDL5 LOC8023533 PTHR19848:SF10 WD40 REPEAT PROTEIN NOTCHLESS PROTEIN HOMOLOG 1 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115314093|UniProtKB=A0ACM8DTB8 A0ACM8DTB8 LOC115314093 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050534|UniProtKB=A0ACM8EE14 A0ACM8EE14 LOC8050534 PTHR46896:SF3 SENTRIN-SPECIFIC PROTEASE FI06413P-RELATED protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115317796|UniProtKB=A0ACM8ES50 A0ACM8ES50 LOC115317796 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115308210|UniProtKB=A0ACM8EBY7 A0ACM8EBY7 LOC115308210 PTHR10106:SF24 CYTOCHROME B561-RELATED NO EXTENDED MEMORY, ISOFORM A catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8027009|UniProtKB=A0ACM8DPH2 A0ACM8DPH2 PTHR11309:SF90 FRIZZLED FRIZZLED-8 transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515 canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;non-canonical Wnt signaling pathway#GO:0035567;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Wnt signaling pathway#P00057>Frizzled#P01428;Cadherin signaling pathway#P00012>Frizzled#P00475;Angiogenesis#P00005>Fzd#P00189 IXOSC|EnsemblGenome=LOC8038438|UniProtKB=A0ACM8FI56 A0ACM8FI56 LOC8038438 PTHR13707:SF23 KETOACID-COENZYME A TRANSFERASE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8030520|UniProtKB=A0ACM8G3P4 A0ACM8G3P4 LOC8030520 PTHR31781:SF1 UNC80 PROTEIN UNC-80 HOMOLOG monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;sodium ion transport#GO:0006814;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;homeostatic process#GO:0042592;metal ion transport#GO:0030001;regulation of cellular process#GO:0050794;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of system process#GO:0044057;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion homeostasis#GO:0050801;monoatomic ion transmembrane transport#GO:0034220;regulation of multicellular organismal process#GO:0051239;monoatomic cation transmembrane transport#GO:0098655;biological regulation#GO:0065007 axon#GO:0030424;cation channel complex#GO:0034703;sodium channel complex#GO:0034706;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;neuron projection#GO:0043005;membrane protein complex#GO:0098796;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8037017|UniProtKB=A0ACM8E7L7 A0ACM8E7L7 LOC8037017 PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 transporter#PC00227 IXOSC|EnsemblGenome=LOC115308878|UniProtKB=A0ACM8EN09 A0ACM8EN09 LOC115308878 PTHR13318:SF165 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX_LRR-REPEAT PROTEIN FBXL-1 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 IXOSC|EnsemblGenome=LOC115314907|UniProtKB=A0ACM8DUR8 A0ACM8DUR8 LOC115314907 PTHR12001:SF55 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;ketone biosynthetic process#GO:0042181;ubiquinone biosynthetic process#GO:0006744;primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;isoprenoid metabolic process#GO:0006720;isoprenoid biosynthetic process#GO:0008299;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8031708|UniProtKB=A0ACM8DIL5 A0ACM8DIL5 ND-B8 PTHR12878:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B8 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 2 membrane#GO:0016020;oxidoreductase complex#GO:1990204;membrane protein complex#GO:0098796;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;respiratory chain complex I#GO:0045271;catalytic complex#GO:1902494;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8028358|UniProtKB=A0ACM8DSP6 A0ACM8DSP6 LOC8028358 PTHR11183:SF204 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN GLUCOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glucosyltransferase activity#GO:0035251;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;glucosyltransferase activity#GO:0046527 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8042792|UniProtKB=A0ACM8DPD4 A0ACM8DPD4 Cdc16 PTHR12558:SF9 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 16 HOMOLOG enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of mitotic cell cycle#GO:0007346;positive regulation of cellular process#GO:0048522;positive regulation of mitotic cell cycle#GO:0045931;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of mitotic nuclear division#GO:0007088;regulation of mitotic sister chromatid separation#GO:0010965;macromolecule metabolic process#GO:0043170;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;cell division#GO:0051301;modification-dependent protein catabolic process#GO:0019941;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of cell cycle phase transition#GO:1901987;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;regulation of chromosome separation#GO:1905818;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;regulation of organelle organization#GO:0033043;protein modification by small protein conjugation#GO:0032446;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;positive regulation of organelle organization#GO:0010638;regulation of mitotic cell cycle phase transition#GO:1901990;modification-dependent macromolecule catabolic process#GO:0043632;anaphase-promoting complex-dependent catabolic process#GO:0031145;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647 anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8038097|UniProtKB=A0ACM8DN62 A0ACM8DN62 Hmt-1 PTHR24221:SF664 ATP-BINDING CASSETTE SUB-FAMILY B ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 6 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115309698|UniProtKB=A0ACM8DP37 A0ACM8DP37 LOC115309698 PTHR14464:SF4 EXONUCLEASE V EXONUCLEASE V DNA exonuclease activity#GO:0004529;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on DNA#GO:0140097;exonuclease activity#GO:0004527;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;5'-3' exonuclease activity#GO:0008409;hydrolase activity#GO:0016787 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;interstrand cross-link repair#GO:0036297;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8034168|UniProtKB=A0ACM8DRD4 A0ACM8DRD4 PAN3 PTHR12272:SF11 DEADENYLATION COMPLEX SUBUNIT PAN3 PAN2-PAN3 DEADENYLATION COMPLEX SUBUNIT PAN3 nucleic acid binding#GO:0003676;binding#GO:0005488;poly(A) binding#GO:0008143;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC8041688|UniProtKB=A0ACM8E7G9 A0ACM8E7G9 LOC8041688 PTHR15508:SF8 RIBOSOMAL PROTEIN S6 KINASE LD24550P protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8034467|UniProtKB=A0ACM8DJD2 A0ACM8DJD2 bonsai PTHR46685:SF1 28S RIBOSOMAL PROTEIN S15, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN US15M protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121834582|UniProtKB=A0ACM8FP66 A0ACM8FP66 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115326848|UniProtKB=A0ACM8EYW9 A0ACM8EYW9 LOC115326848 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8030823|UniProtKB=A0ACM8FXG7 A0ACM8FXG7 LOC8030823 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121834790|UniProtKB=A0ACM8FR45 A0ACM8FR45 LOC121834790 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029552|UniProtKB=A0ACM8E158 A0ACM8E158 LOC8029552 PTHR23199:SF19 NEUROTROPHIN 1-RELATED SPAETZLE DOMAIN-CONTAINING PROTEIN receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;central nervous system development#GO:0007417;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;developmental process#GO:0032502;multicellular organism development#GO:0007275;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;multicellular organismal process#GO:0032501;defense response to other organism#GO:0098542;nervous system development#GO:0007399;response to other organism#GO:0051707 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8034743|UniProtKB=A0ACM8DX67 A0ACM8DX67 LOC8034743 PTHR10082:SF60 INTEGRIN BETA SUBUNIT INTEGRIN BETA-PS cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;signal transduction#GO:0007165;cellular process#GO:0009987;cell migration#GO:0016477;biological regulation#GO:0065007;cell adhesion mediated by integrin#GO:0033627;cell surface receptor signaling pathway#GO:0007166;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell motility#GO:0048870;signaling#GO:0023052;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell communication#GO:0007154;cell-substrate adhesion#GO:0031589 protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cell surface#GO:0009986;signaling receptor complex#GO:0043235;anchoring junction#GO:0070161;integrin complex#GO:0008305;cell junction#GO:0030054 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 IXOSC|EnsemblGenome=LOC120837689|UniProtKB=A0ACM8FR03 A0ACM8FR03 BBS8 PTHR44177:SF1 TETRATRICOPEPTIDE REPEAT PROTEIN 8 TETRATRICOPEPTIDE REPEAT PROTEIN 8 cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;cilium assembly#GO:0060271 microtubule cytoskeleton#GO:0015630;BBSome#GO:0034464;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intracellular organelle#GO:0043229;cilium#GO:0005929;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115317725|UniProtKB=A0ACM8F6B5 A0ACM8F6B5 LOC115317725 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843569|UniProtKB=A0ACM8FG31 A0ACM8FG31 LOC120843569 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC115317877|UniProtKB=A0ACM8EQI1 A0ACM8EQI1 LOC115317877 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027242|UniProtKB=A0ACM8E3W7 A0ACM8E3W7 Stim PTHR15136:SF5 STROMAL INTERACTION MOLECULE HOMOLOG STROMAL INTERACTION MOLECULE HOMOLOG molecular function regulator activity#GO:0098772;calcium channel regulator activity#GO:0005246;ion channel regulator activity#GO:0099106;cation binding#GO:0043169;channel regulator activity#GO:0016247;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;transporter regulator activity#GO:0141108;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;monoatomic ion homeostasis#GO:0050801;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120851178|UniProtKB=A0ACM8FSS0 A0ACM8FSS0 LOC120851178 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8050569|UniProtKB=A0ACM8FNY7 A0ACM8FNY7 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme regulator activity#GO:0030234;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755 positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of protein ubiquitination#GO:0031398;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8036674|UniProtKB=A0ACM8E3J6 A0ACM8E3J6 LOC8036674 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8035989|UniProtKB=A0ACM8EBZ8 A0ACM8EBZ8 PTHR12300:SF197 HVA22-LIKE PROTEINS LP05237P-RELATED microtubule binding#GO:0008017;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 endomembrane system organization#GO:0010256;endoplasmic reticulum tubular network organization#GO:0071786;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum organization#GO:0007029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic microtubule#GO:0005881;microtubule#GO:0005874;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;supramolecular complex#GO:0099080;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;endoplasmic reticulum tubular network#GO:0071782;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;cytoskeleton#GO:0005856;endoplasmic reticulum#GO:0005783 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8023330|UniProtKB=A0ACM8DZY1 A0ACM8DZY1 PTHR12688:SF5 DYNEIN LIGHT INTERMEDIATE CHAIN DYNEIN LIGHT INTERMEDIATE CHAIN protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;dynein complex#GO:0030286;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 IXOSC|EnsemblGenome=LOC121835488|UniProtKB=A0ACM8FUC3 A0ACM8FUC3 LOC121835488 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8040902|UniProtKB=A0ACM8EZA1 A0ACM8EZA1 LOC8040902 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165 reductase#PC00198 IXOSC|EnsemblGenome=LOC8052282|UniProtKB=A0ACM8EH54 A0ACM8EH54 LOC8052282 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;heme binding#GO:0020037 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;steroid metabolic process#GO:0008202;response to stimulus#GO:0050896;response to chemical#GO:0042221;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121833933|UniProtKB=A0ACM8FNN9 A0ACM8FNN9 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030253|UniProtKB=A0ACM8EUN9 A0ACM8EUN9 Tmf PTHR46515:SF1 TATA ELEMENT MODULATORY FACTOR TMF1 TATA ELEMENT MODULATORY FACTOR cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8028363|UniProtKB=A0ACM8FLA5 A0ACM8FLA5 LOC8028363 PTHR10110:SF98 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER metal cation:proton antiporter activity#GO:0051139;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324 homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8053544|UniProtKB=A0ACM8DL99 A0ACM8DL99 Non3 PTHR12728:SF0 BRIX DOMAIN CONTAINING PROTEIN RIBOSOME PRODUCTION FACTOR 2 HOMOLOG nucleic acid binding#GO:0003676;binding#GO:0005488;rRNA binding#GO:0019843;RNA binding#GO:0003723 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8043852|UniProtKB=A0ACM8E0X8 A0ACM8E0X8 LOC8043852 PTHR12822:SF2 PROTEIN YIPF PROTEIN YIPF Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8037513|UniProtKB=A0ACM8EZQ8 A0ACM8EZQ8 LOC8037513 PTHR10098:SF108 RAPSYN-RELATED TETRATRICOPEPTIDE REPEAT PROTEIN 28 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115328910|UniProtKB=A0ACM8E999 A0ACM8E999 LOC115328910 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028153|UniProtKB=A0ACM8E0J8 A0ACM8E0J8 LOC8028153 PTHR11132:SF238 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER H1 active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;antiporter activity#GO:0015297 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;nitrogen compound transport#GO:0071705;nucleotide-sugar transmembrane transport#GO:0015780;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;cis-Golgi network#GO:0005801;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115322025|UniProtKB=A0ACM8ENC0 A0ACM8ENC0 LOC115322025 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115324926|UniProtKB=A0ACM8G0X5 A0ACM8G0X5 LOC115324926 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325155|UniProtKB=A0ACM8ESJ2 A0ACM8ESJ2 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024264|UniProtKB=A0ACM8F3D4 A0ACM8F3D4 LOC8024264 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035186|UniProtKB=A0ACM8DJP2 A0ACM8DJP2 LOC8035186 PTHR23292:SF6 LIPOPOLYSACCHARIDE-INDUCED TUMOR NECROSIS FACTOR-ALPHA FACTOR FI16602P1-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;zinc ion binding#GO:0008270;transition metal ion binding#GO:0046914 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121835778|UniProtKB=A0ACM8FWW7 A0ACM8FWW7 LOC121835778 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317878|UniProtKB=A0ACM8DY14 A0ACM8DY14 LOC115317878 PTHR45695:SF42 LEUCOKININ RECEPTOR-RELATED GALANIN-LIKE G PROTEIN-COUPLED RECEPTOR NPR-9 transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8030419|UniProtKB=A0ACM8E4U9 A0ACM8E4U9 dally PTHR10822:SF29 GLYPICAN DIVISION ABNORMALLY DELAYED PROTEIN positive regulation of signaling#GO:0023056;regulation of protein localization#GO:0032880;regulation of signaling#GO:0023051;cell motility#GO:0048870;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of localization#GO:0032879;regulation of response to stimulus#GO:0048583;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical Wnt signaling pathway#GO:0060828;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987 extracellular region#GO:0005576;cell surface#GO:0009986;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120846640|UniProtKB=A0ACM8F2T4 A0ACM8F2T4 LOC120846640 PTHR46481:SF16 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 BED-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846187|UniProtKB=A0ACM8FH02 A0ACM8FH02 LOC120846187 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315782|UniProtKB=A0ACM8DVM9 A0ACM8DVM9 LOC115315782 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8025114|UniProtKB=A0ACM8F6E0 A0ACM8F6E0 LOC8025114 PTHR14950:SF82 DICER-RELATED ENDORIBONUCLEASE DICER catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;RNA binding#GO:0003723;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;binding#GO:0005488;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cell death#GO:0008219;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;apoptotic DNA fragmentation#GO:0006309;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;siRNA processing#GO:0030422;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;DNA catabolic process#GO:0006308;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;cellular component disassembly#GO:0022411;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555 IXOSC|EnsemblGenome=LOC120838729|UniProtKB=A0ACM8ELE9 A0ACM8ELE9 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029521|UniProtKB=A0ACM8FIF9 A0ACM8FIF9 LOC8029521 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8032428|UniProtKB=A0ACM8E5G5 A0ACM8E5G5 LOC8032428 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121835199|UniProtKB=A0ACM8FTU7 A0ACM8FTU7 LOC121835199 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;small molecule catabolic process#GO:0044282;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8042888|UniProtKB=A0ACM8EAN0 A0ACM8EAN0 LOC8042888 PTHR15398:SF4 BROMODOMAIN-CONTAINING PROTEIN 8 BROMODOMAIN-CONTAINING PROTEIN 8 IXOSC|EnsemblGenome=LOC8036962|UniProtKB=A0ACM8F420 A0ACM8F420 LOC8036962 PTHR13610:SF9 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN ATP SYNTHASE SUBUNIT C LYSINE N-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278 biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120841203|UniProtKB=A0ACM8FXD7 A0ACM8FXD7 LOC120841203 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031589|UniProtKB=A0ACM8DNR8 A0ACM8DNR8 LOC8031589 PTHR48407:SF1 CRANIOFACIAL DEVELOPMENT PROTEIN 1 HETEROCHROMATIN-STABILIZING PROTEIN CFDP1 cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338 ATPase complex#GO:1904949;intracellular organelle#GO:0043229;Swr1 complex#GO:0000812;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8040513|UniProtKB=A0ACM8DKI9 A0ACM8DKI9 LOC8040513 PTHR24340:SF82 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN VND double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC121835146|UniProtKB=A0ACM8FTL7 A0ACM8FTL7 LOC121835146 PTHR24241:SF190 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CARDIOACCELERATORY PEPTIDE RECEPTOR-LIKE PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8036601|UniProtKB=A0ACM8EMT2 A0ACM8EMT2 LOC8036601 PTHR42985:SF51 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER LD47995P-RELATED secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC121837404|UniProtKB=A0ACM8G4I0 A0ACM8G4I0 LOC121837404 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312010|UniProtKB=A0ACM8DRJ8 A0ACM8DRJ8 LOC115312010 PTHR45036:SF1 METHYLTRANSFERASE LIKE 7B THIOL METHYLTRANSFERASE 1A transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121837282|UniProtKB=A0ACM8G411 A0ACM8G411 LOC121837282 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120840414|UniProtKB=A0ACM8G0A3 A0ACM8G0A3 LOC120840414 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8031351|UniProtKB=A0ACM8DUL1 A0ACM8DUL1 LOC8031351 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8052467|UniProtKB=A0ACM8E7C1 A0ACM8E7C1 Mfe2 PTHR45024:SF2 DEHYDROGENASES, SHORT CHAIN SCP2 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;carbon-oxygen lyase activity#GO:0016835;oxidoreductase activity#GO:0016491;lyase activity#GO:0016829;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;hydro-lyase activity#GO:0016836 monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121048149|UniProtKB=A0ACM8FKH8 A0ACM8FKH8 LOC121048149 PTHR23235:SF183 KRUEPPEL-LIKE TRANSCRIPTION FACTOR DENDRITIC ARBOR REDUCTION PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8030534|UniProtKB=A0ACM8DH86 A0ACM8DH86 LOC8030534 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121837562|UniProtKB=A0ACM8G3Z3 A0ACM8G3Z3 LOC121837562 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846131|UniProtKB=A0ACM8F2J1 A0ACM8F2J1 LOC120846131 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115333102|UniProtKB=A0ACM8EHW4 A0ACM8EHW4 LOC115333102 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8023778|UniProtKB=A0ACM8EM51 A0ACM8EM51 Ncc69 PTHR11827:SF103 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS SODIUM CHLORIDE COTRANSPORTER 69, ISOFORM E chloride transmembrane transporter activity#GO:0015108;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;transport#GO:0006810;chloride transport#GO:0006821;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120836243|UniProtKB=A0ACM8ETU5 A0ACM8ETU5 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850159|UniProtKB=A0ACM8F9F2 A0ACM8F9F2 LOC120850159 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120845701|UniProtKB=A0ACM8FQW0 A0ACM8FQW0 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115323692|UniProtKB=A0ACM8E3W2 A0ACM8E3W2 LOC115323692 PTHR23098:SF16 AGAP001331-PA-RELATED GT1 DOMAIN-CONTAINING PROTEIN nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8023654|UniProtKB=A0ACM8E1P2 A0ACM8E1P2 LOC8023654 PTHR10972:SF141 OXYSTEROL-BINDING PROTEIN-RELATED PH DOMAIN-CONTAINING PROTEIN steroid binding#GO:0005496;lipid binding#GO:0008289;binding#GO:0005488;sterol binding#GO:0032934 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120838344|UniProtKB=A0ACM8FVD7 A0ACM8FVD7 LOC120838344 PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;citrate transmembrane transporter activity#GO:0015137;C4-dicarboxylate transmembrane transporter activity#GO:0015556 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;tricarboxylic acid transport#GO:0006842;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;C4-dicarboxylate transport#GO:0015740;citrate transport#GO:0015746;dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8051772|UniProtKB=A0ACM8E520 A0ACM8E520 LOC8051772 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8052742|UniProtKB=A0ACM8DM03 A0ACM8DM03 LOC8052742 PTHR19303:SF80 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8024647|UniProtKB=A0ACM8DIG6 A0ACM8DIG6 LOC8024647 PTHR13016:SF0 AMMECR1 HOMOLOG AMME SYNDROME CANDIDATE GENE 1 PROTEIN IXOSC|EnsemblGenome=LOC8027304|UniProtKB=A0ACM8FHM0 A0ACM8FHM0 LOC8027304 PTHR45902:SF7 LATROPHILIN RECEPTOR-LIKE PROTEIN A G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115319493|UniProtKB=A0ACM8ERJ3 A0ACM8ERJ3 LOC115319493 PTHR46697:SF1 FORMIN-BINDING PROTEIN 4 FORMIN-BINDING PROTEIN 4 IXOSC|EnsemblGenome=LOC120845811|UniProtKB=A0ACM8F0W1 A0ACM8F0W1 LOC120845811 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840351|UniProtKB=A0ACM8FEK4 A0ACM8FEK4 LOC120840351 PTHR31912:SF38 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037658|UniProtKB=A0ACM8DMA1 A0ACM8DMA1 LOC8037658 PTHR46027:SF1 PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR PEROXISOMAL TARGETING SIGNAL 2 RECEPTOR signal sequence receptor activity#GO:0005048 protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;organelle organization#GO:0006996;macromolecule localization#GO:0033036;peroxisome organization#GO:0007031;protein transport#GO:0015031;peroxisomal transport#GO:0043574;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;cellular component organization#GO:0016043;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;cytosol#GO:0005829;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;microbody#GO:0042579 IXOSC|EnsemblGenome=LOC120836324|UniProtKB=A0ACM8F1L8 A0ACM8F1L8 LOC120836324 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115310744|UniProtKB=A0ACM8DQ30 A0ACM8DQ30 Rnf146 PTHR13417:SF2 E3 UBIQUITIN-PROTEIN LIGASE RNF146 E3 UBIQUITIN-PROTEIN LIGASE RNF146 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;carbohydrate derivative binding#GO:0097367;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787 ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8026266|UniProtKB=A0ACM8DVM2 A0ACM8DVM2 LOC8026266 PTHR43968:SF6 FAMILY NOT NAMED GLUTATHIONE S-TRANSFERASE OMEGA oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;antioxidant activity#GO:0016209;disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8028393|UniProtKB=A0ACM8EXR0 A0ACM8EXR0 LOC8028393 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028521|UniProtKB=A0ACM8EPJ9 A0ACM8EPJ9 Rpb7 PTHR12709:SF4 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB7 DNA-templated transcription initiation#GO:0006352;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366 organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC120846656|UniProtKB=A0ACM8FUX9 A0ACM8FUX9 LOC120846656 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC120840439|UniProtKB=A0ACM8EQ49 A0ACM8EQ49 LOC120840439 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC115322291|UniProtKB=A0ACM8EKU9 A0ACM8EKU9 LOC115322291 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040083|UniProtKB=A0ACM8F4C7 A0ACM8F4C7 LOC8040083 PTHR45712:SF36 AGAP008170-PA PODOCAN ISOFORM X1 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC115333062|UniProtKB=A0ACM8F3G5 A0ACM8F3G5 LOC115333062 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115312056|UniProtKB=A0ACM8DRV8 A0ACM8DRV8 LOC115312056 PTHR11409:SF43 ADENOSINE DEAMINASE ADENOSINE DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;deaminase activity#GO:0019239;adenosine deaminase activity#GO:0004000;catalytic activity#GO:0003824 carbohydrate derivative catabolic process#GO:1901136;small molecule catabolic process#GO:0044282;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;nucleobase-containing small molecule catabolic process#GO:0034656;nucleoside catabolic process#GO:0009164;purine nucleoside metabolic process#GO:0042278;purine-containing compound biosynthetic process#GO:0072522;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;adenosine metabolic process#GO:0046085;glycosyl compound catabolic process#GO:1901658;nucleobase-containing compound catabolic process#GO:0034655;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside catabolic process#GO:0006152;carbohydrate derivative biosynthetic process#GO:1901137;purine-containing compound catabolic process#GO:0072523;purine nucleobase metabolic process#GO:0006144;small molecule biosynthetic process#GO:0044283;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 deaminase#PC00088 Adenine and hypoxanthine salvage pathway#P02723>Deoxyadenosine deaminase#P02807;Adenine and hypoxanthine salvage pathway#P02723>Adenosine deaminase#P02811 IXOSC|EnsemblGenome=LOC8033279|UniProtKB=A0ACM8E7I0 A0ACM8E7I0 LOC8033279 PTHR12914:SF2 PARTNER OF SLD5 DNA REPLICATION COMPLEX GINS PROTEIN PSF1 cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle process#GO:0022402;DNA replication#GO:0006260;mitotic cell cycle#GO:0000278;DNA strand elongation involved in DNA replication#GO:0006271;DNA-templated DNA replication#GO:0006261;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;cell cycle DNA replication#GO:0044786;DNA metabolic process#GO:0006259;nuclear DNA replication#GO:0033260;mitotic DNA replication#GO:1902969;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047 GINS complex#GO:0000811;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;DNA replication preinitiation complex#GO:0031261;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;CMG complex#GO:0071162;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8032524|UniProtKB=A0ACM8FD96 A0ACM8FD96 LOC8032524 PTHR13483:SF11 BOX C_D SNORNA PROTEIN 1-RELATED ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 3 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;cellular component assembly#GO:0022607;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115328311|UniProtKB=A0ACM8F3C8 A0ACM8F3C8 LOC115328311 PTHR15079:SF3 MYD88 MYELOID DIFFERENTIATION PRIMARY RESPONSE PROTEIN MYD88 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 cell surface receptor signaling pathway#GO:0007166;positive regulation of response to external stimulus#GO:0032103;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;defense response to symbiont#GO:0140546;positive regulation of immune system process#GO:0002684;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;regulation of response to external stimulus#GO:0032101;defense response to other organism#GO:0098542;defense response to bacterium#GO:0042742;immune system process#GO:0002376;immune response-regulating signaling pathway#GO:0002764;defense response to Gram-positive bacterium#GO:0050830;regulation of biological process#GO:0050789;signaling#GO:0023052;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;defense response#GO:0006952;pattern recognition receptor signaling pathway#GO:0002221;response to external stimulus#GO:0009605;positive regulation of response to biotic stimulus#GO:0002833;innate immune response#GO:0045087;regulation of innate immune response#GO:0045088;positive regulation of innate immune response#GO:0045089;immune response#GO:0006955;activation of innate immune response#GO:0002218;response to other organism#GO:0051707;toll-like receptor 4 signaling pathway#GO:0034142;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;response to bacterium#GO:0009617;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;innate immune response-activating signaling pathway#GO:0002758;regulation of response to biotic stimulus#GO:0002831;immune response-activating cell surface receptor signaling pathway#GO:0002429;response to external biotic stimulus#GO:0043207;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>MyD88#P01377;Toll pathway-drosophila#P06217>MyD88#P06346 IXOSC|EnsemblGenome=LOC115321899|UniProtKB=A0ACM8EI95 A0ACM8EI95 LOC115321899 PTHR15574:SF43 WD REPEAT DOMAIN-CONTAINING FAMILY DDB1- AND CUL4-ASSOCIATED FACTOR 5 negative regulation of metabolic process#GO:0009892;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of lipid biosynthetic process#GO:0046890;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;negative regulation of biological process#GO:0048519;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;regulation of lipid metabolic process#GO:0019216 cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120839923|UniProtKB=A0ACM8END3 A0ACM8END3 LOC120839923 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041747|UniProtKB=A0ACM8FV46 A0ACM8FV46 LOC8041747 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8025480|UniProtKB=A0ACM8DJB2 A0ACM8DJB2 Hs2st PTHR12129:SF17 HEPARAN SULFATE 2-O-SULFOTRANSFERASE HEPARAN SULFATE 2-O-SULFOTRANSFERASE 1 sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 proteoglycan metabolic process#GO:0006029;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8025820|UniProtKB=A0ACM8FLQ4 A0ACM8FLQ4 LOC8025820 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121048350|UniProtKB=A0ACM8FHY7 A0ACM8FHY7 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025812|UniProtKB=A0ACM8DQ97 A0ACM8DQ97 LOC8025812 PTHR10972:SF136 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN steroid binding#GO:0005496;lipid binding#GO:0008289;binding#GO:0005488;sterol binding#GO:0032934 cytosol#GO:0005829;membrane#GO:0016020;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115310190|UniProtKB=A0ACM8DPG7 A0ACM8DPG7 LOC115310190 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein ligase activity#GO:0061659 protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;metabolic process#GO:0008152;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;protein sumoylation#GO:0016925;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 IXOSC|EnsemblGenome=LOC8023663|UniProtKB=A0ACM8FQG0 A0ACM8FQG0 LOC8023663 PTHR10256:SF0 SELENIDE, WATER DIKINASE INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835478|UniProtKB=A0ACM8FUY9 A0ACM8FUY9 LOC121835478 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838265|UniProtKB=A0ACM8EK63 A0ACM8EK63 LOC120838265 PTHR11177:SF144 CHITINASE CHITINASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;chitin metabolic process#GO:0006030 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115308528|UniProtKB=A0ACM8DMJ6 A0ACM8DMJ6 LOC115308528 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC120845394|UniProtKB=A0ACM8FGQ9 A0ACM8FGQ9 LOC120845394 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115328183|UniProtKB=A0ACM8FL69 A0ACM8FL69 LOC115328183 PTHR15999:SF2 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115315790|UniProtKB=A0ACM8F8L7 A0ACM8F8L7 LOC115315790 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 IXOSC|EnsemblGenome=LOC115312705|UniProtKB=A0ACM8DS39 A0ACM8DS39 LOC115312705 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC115316272|UniProtKB=A0ACM8EQZ9 A0ACM8EQZ9 LOC115316272 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120841065|UniProtKB=A0ACM8ERV0 A0ACM8ERV0 LOC120841065 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120842889|UniProtKB=A0ACM8EVY5 A0ACM8EVY5 LOC120842889 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321842|UniProtKB=A0ACM8EJ40 A0ACM8EJ40 LOC115321842 PTHR33066:SF6 INTEGRASE_SAM-LIKE_N DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025777|UniProtKB=A0ACM8DQM7 A0ACM8DQM7 LOC8025777 PTHR19317:SF0 PRENYLATED RAB ACCEPTOR 1-RELATED PRENYLATED RAB ACCEPTOR PROTEIN 1 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8042033|UniProtKB=A0ACM8DKV0 A0ACM8DKV0 SmE PTHR11193:SF0 SMALL NUCLEAR RIBONUCLEOPROTEIN E SMALL NUCLEAR RIBONUCLEOPROTEIN E spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;U5 snRNP#GO:0005682;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;U1 snRNP#GO:0005685;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;U4 snRNP#GO:0005687;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC115314322|UniProtKB=A0ACM8DTM5 A0ACM8DTM5 LOC115314322 PTHR11306:SF0 NIEMANN PICK TYPE C2 PROTEIN NPC2-RELATED LP08842P-RELATED binding#GO:0005488;sterol binding#GO:0032934;lipid binding#GO:0008289;steroid binding#GO:0005496 macromolecule localization#GO:0033036;lipid transport#GO:0006869;lipid localization#GO:0010876;transport#GO:0006810;localization#GO:0051179;sterol transport#GO:0015918;establishment of localization#GO:0051234;organic hydroxy compound transport#GO:0015850 IXOSC|EnsemblGenome=LOC121836806|UniProtKB=A0ACM8G0Q7 A0ACM8G0Q7 LOC121836806 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8023245|UniProtKB=A0ACM8FK32 A0ACM8FK32 LOC8023245 PTHR15116:SF16 DNA-BINDING PROTEIN SATB FAMILY MEMBER DEFECTIVE PROVENTRICULUS, ISOFORM A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;Lambda repressor-like transcription factor#PC00245 IXOSC|EnsemblGenome=LOC115310957|UniProtKB=A0ACM8F0J3 A0ACM8F0J3 LOC115310957 PTHR23235:SF130 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 367 transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120836249|UniProtKB=A0ACM8FMB4 A0ACM8FMB4 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833192|UniProtKB=A0ACM8FJV3 A0ACM8FJV3 LOC121833192 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8035978|UniProtKB=A0ACM8ELA7 A0ACM8ELA7 LOC8035978 PTHR22997:SF0 PIH1 DOMAIN-CONTAINING PROTEIN 1 PIH1 DOMAIN-CONTAINING PROTEIN 1 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;protein-containing complex assembly#GO:0065003;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular component assembly#GO:0022607;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribonucleoprotein complex#GO:1990904 IXOSC|EnsemblGenome=LOC120846787|UniProtKB=A0ACM8F303 A0ACM8F303 LOC120846787 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC115323234|UniProtKB=A0ACM8F2Z8 A0ACM8F2Z8 LOC115323234 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035320|UniProtKB=A0ACM8DXD0 A0ACM8DXD0 LOC8035320 PTHR43948:SF10 DNAJ HOMOLOG SUBFAMILY B MRJ, ISOFORM E binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120840895|UniProtKB=A0ACM8G7Y6 A0ACM8G7Y6 Fmr1 PTHR10603:SF7 FRAGILE X MENTAL RETARDATION SYNDROME-RELATED PROTEIN FRAGILE X MESSENGER RIBONUCLEOPROTEIN 1 HOMOLOG RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 positive regulation of cell differentiation#GO:0045597;animal organ development#GO:0048513;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;regulation of protein metabolic process#GO:0051246;positive regulation of cell development#GO:0010720;regulation of multicellular organismal process#GO:0051239;positive regulation of macromolecule metabolic process#GO:0010604;regulation of trans-synaptic signaling#GO:0099177;positive regulation of protein metabolic process#GO:0051247;regulation of signaling#GO:0023051;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of multicellular organismal process#GO:0051240;regulation of multicellular organismal development#GO:2000026;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;positive regulation of nervous system development#GO:0051962;developmental process#GO:0032502;positive regulation of developmental process#GO:0051094;transport#GO:0006810;regulation of cell differentiation#GO:0045595;regulation of synaptic plasticity#GO:0048167;post-transcriptional regulation of gene expression#GO:0010608;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of neuronal synaptic plasticity#GO:0048168;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;positive regulation of translation#GO:0045727;regulation of RNA metabolic process#GO:0051252;localization#GO:0051179;positive regulation of biosynthetic process#GO:0009891;nucleic acid transport#GO:0050657;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of neurogenesis#GO:0050767;mRNA transport#GO:0051028;modulation of chemical synaptic transmission#GO:0050804;regulation of developmental process#GO:0050793;establishment of RNA localization#GO:0051236;regulation of cell communication#GO:0010646;positive regulation of neurogenesis#GO:0050769;regulation of macromolecule metabolic process#GO:0060255;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;regulation of cellular process#GO:0050794;RNA transport#GO:0050658 neuron projection#GO:0043005;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation factor#PC00223 IXOSC|EnsemblGenome=LOC8031865|UniProtKB=A0ACM8FT96 A0ACM8FT96 LOC8031865 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808 cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120842944|UniProtKB=A0ACM8EW40 A0ACM8EW40 LOC120842944 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121838337|UniProtKB=A0ACM8G7H9 A0ACM8G7H9 LOC121838337 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120843222|UniProtKB=A0ACM8EVM2 A0ACM8EVM2 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8039036|UniProtKB=A0ACM8DS48 A0ACM8DS48 LOC8039036 PTHR45902:SF6 LATROPHILIN RECEPTOR-LIKE PROTEIN A G-PROTEIN COUPLED RECEPTOR MTH 12-RELATED transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121835273|UniProtKB=A0ACM8FS89 A0ACM8FS89 LOC121835273 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8042518|UniProtKB=A0ACM8DKY7 A0ACM8DKY7 LOC8042518 PTHR10340:SF63 SPHINGOMYELIN PHOSPHODIESTERASE METALLOPHOS DOMAIN-CONTAINING PROTEIN phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121836108|UniProtKB=A0ACM8G4N8 A0ACM8G4N8 LOC121837685 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8051684|UniProtKB=A0ACM8E690 A0ACM8E690 LOC8051684 PTHR13847:SF294 SARCOSINE DEHYDROGENASE-RELATED FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 1 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;mitochondrial respiratory chain complex I assembly#GO:0032981;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120836763|UniProtKB=A0ACM8G263 A0ACM8G263 LOC120836763 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;polyamine biosynthetic process#GO:0006596;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;amine metabolic process#GO:0009308;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC120840810|UniProtKB=A0ACM8G8E8 A0ACM8G8E8 LOC120840810 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837990|UniProtKB=A0ACM8G740 A0ACM8G740 LOC121837990 PTHR16442:SF1 RING FINGER PROTEIN 17 RING FINGER PROTEIN 17 IXOSC|EnsemblGenome=LOC8030512|UniProtKB=A0ACM8EFI0 A0ACM8EFI0 LOC8030512 PTHR10408:SF8 STEROL O-ACYLTRANSFERASE O-ACYLTRANSFERASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;steroid metabolic process#GO:0008202;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cholesterol metabolic process#GO:0008203;lipid metabolic process#GO:0006629;sterol metabolic process#GO:0016125 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8032280|UniProtKB=A0ACM8DJC9 A0ACM8DJC9 LOC8032280 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052;cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056 hydrolase#PC00121;galactosidase#PC00104 IXOSC|EnsemblGenome=LOC121047603|UniProtKB=A0ACM8FGA0 A0ACM8FGA0 LOC121047603 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024479|UniProtKB=A0ACM8DIC6 A0ACM8DIC6 LOC8024479 PTHR12970:SF1 PROTEASOME ASSEMBLY CHAPERONE 2 PROTEASOME ASSEMBLY CHAPERONE 2 protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8038186|UniProtKB=A0ACM8E5B5 A0ACM8E5B5 LOC8038186 PTHR48038:SF6 RIBONUCLEOPROTEIN RB97D RIBONUCLEOPROTEIN RB97D IXOSC|EnsemblGenome=LOC8050806|UniProtKB=A0ACM8DLU4 A0ACM8DLU4 LOC8050806 PTHR22761:SF10 CHARGED MULTIVESICULAR BODY PROTEIN BCDNA.GH08385-RELATED late endosome to vacuole transport#GO:0045324;membrane assembly#GO:0071709;cellular component organization#GO:0016043;localization#GO:0051179;cellular localization#GO:0051641;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endosomal transport#GO:0016197;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;nuclear envelope organization#GO:0006998;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907 cytoplasmic side of membrane#GO:0098562;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;side of membrane#GO:0098552;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasmic side of plasma membrane#GO:0009898;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115310647|UniProtKB=A0ACM8DPZ0 A0ACM8DPZ0 LOC115310647 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC121048479|UniProtKB=A0ACM8FSQ2 A0ACM8FSQ2 LOC121048479 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8028959|UniProtKB=A0ACM8E108 A0ACM8E108 LOC8028959 PTHR12260:SF6 DAMAGE-CONTROL PHOSPHATASE ARMT1 DAMAGE-CONTROL PHOSPHATASE 1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8024509|UniProtKB=A0ACM8DID3 A0ACM8DID3 Atg101 PTHR13292:SF0 AUTOPHAGY-RELATED PROTEIN 101 AUTOPHAGY-RELATED PROTEIN 101 kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 metabolic process#GO:0008152;organelle assembly#GO:0070925;autophagosome assembly#GO:0000045;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization or biogenesis#GO:0071840;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;macroautophagy#GO:0016236;catabolic process#GO:0009056;cellular component assembly#GO:0022607 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8052466|UniProtKB=A0ACM8E7E8 A0ACM8E7E8 Su(var)2-10 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I acyltransferase activity#GO:0016746;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;protein sumoylation#GO:0016925;regulation of gene expression#GO:0010468 intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 IXOSC|EnsemblGenome=LOC115326703|UniProtKB=A0ACM8E6Y5 A0ACM8E6Y5 LOC115326703 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120837516|UniProtKB=A0ACM8EH40 A0ACM8EH40 LOC120837516 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter#PC00227 IXOSC|EnsemblGenome=LOC8043546|UniProtKB=A0ACM8E5P7 A0ACM8E5P7 LOC8043546 PTHR24346:SF49 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE NIM1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signal transduction#GO:0035556;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8037915|UniProtKB=A0ACM8DK26 A0ACM8DK26 LOC8037915 PTHR11559:SF370 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE-RELATED esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 IXOSC|EnsemblGenome=LOC8035937|UniProtKB=A0ACM8DP97 A0ACM8DP97 LOC8035937 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8042388|UniProtKB=A0ACM8FLC8 A0ACM8FLC8 LOC8042388 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;response to heat#GO:0009408;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to stimulus#GO:0050896;protein folding#GO:0006457;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC120846166|UniProtKB=A0ACM8F2M1 A0ACM8F2M1 LOC120846166 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838196|UniProtKB=A0ACM8G6K4 A0ACM8G6K4 LOC120838196 PTHR22974:SF23 MIXED LINEAGE PROTEIN KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 cell cycle#GO:0007049;chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8028499|UniProtKB=A0ACM8E0G8 A0ACM8E0G8 LOC8028499 PTHR13568:SF6 FAM11A, B PROTEIN TRANSMEMBRANE PROTEIN 185B IXOSC|EnsemblGenome=LOC115326284|UniProtKB=A0ACM8F0M2 A0ACM8F0M2 LOC115326284 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115331158|UniProtKB=A0ACM8ED69 A0ACM8ED69 PTHR22889:SF0 WD REPEAT-CONTAINING PROTEIN 89 WD REPEAT-CONTAINING PROTEIN 89 IXOSC|EnsemblGenome=LOC8042896|UniProtKB=A0ACM8DKX7 A0ACM8DKX7 PTHR28616:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 125 COILED-COIL DOMAIN-CONTAINING PROTEIN 125 regulation of cellular process#GO:0050794;regulation of Rho protein signal transduction#GO:0035023;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;regulation of cell motility#GO:2000145;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of locomotion#GO:0040012;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8043518|UniProtKB=A0ACM8E5X1 A0ACM8E5X1 LOC8043518 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115309522|UniProtKB=A0ACM8F6B4 A0ACM8F6B4 LOC115309522 PTHR24366:SF140 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS KEKKON 1, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121837317|UniProtKB=A0ACM8G364 A0ACM8G364 LOC121837317 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836031|UniProtKB=A0ACM8FWA1 A0ACM8FWA1 LOC121836031 PTHR16184:SF6 ELONGATOR COMPLEX PROTEIN 6 ELONGATOR COMPLEX PROTEIN 6 elongator holoenzyme complex#GO:0033588;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC115320459|UniProtKB=A0ACM8EVW1 A0ACM8EVW1 LOC115320459 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030881|UniProtKB=A0ACM8EJV8 A0ACM8EJV8 LOC8030881 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC8030676|UniProtKB=A0ACM8E8F7 A0ACM8E8F7 LOC8030676 PTHR11590:SF40 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE HEMOCYTE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 transferase#PC00220 IXOSC|EnsemblGenome=LOC121048527|UniProtKB=A0ACM8FIM1 A0ACM8FIM1 LOC121048527 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8052164|UniProtKB=A0ACM8ED43 A0ACM8ED43 LOC8052164 PTHR21404:SF3 HEN1 SMALL RNA 2'-O-METHYLTRANSFERASE IXOSC|EnsemblGenome=LOC121834129|UniProtKB=A0ACM8FNZ9 A0ACM8FNZ9 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034118|UniProtKB=A0ACM8ECD1 A0ACM8ECD1 LOC8034118 PTHR13229:SF2 PROTEIN KISH-A PROTEIN KISH-A export from cell#GO:0140352;macromolecule localization#GO:0033036;protein localization to extracellular region#GO:0071692;cellular process#GO:0009987;establishment of protein localization#GO:0045184;secretion#GO:0046903;establishment of localization#GO:0051234;localization#GO:0051179;protein secretion#GO:0009306;protein transport#GO:0015031;establishment of protein localization to extracellular region#GO:0035592;secretion by cell#GO:0032940;intracellular protein localization#GO:0008104;transport#GO:0006810 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120840948|UniProtKB=A0ACM8EQ84 A0ACM8EQ84 LOC120840948 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8042573|UniProtKB=A0ACM8DWA3 A0ACM8DWA3 LOC8042573 PTHR43564:SF2 KYNURENINE FORMAMIDASE-LIKE PROTEIN BLR6059 PROTEIN IXOSC|EnsemblGenome=LOC8028202|UniProtKB=A0ACM8EE86 A0ACM8EE86 Dp PTHR12548:SF9 TRANSCRIPTION FACTOR DP TRANSCRIPTION FACTOR DP nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC115327428|UniProtKB=A0ACM8EUJ1 A0ACM8EUJ1 LOC115327428 PTHR43226:SF4 XAA-PRO AMINOPEPTIDASE 3 XAA-PRO AMINOPEPTIDASE 3 catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115323609|UniProtKB=A0ACM8E3T8 A0ACM8E3T8 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115331551|UniProtKB=A0ACM8EKR6 A0ACM8EKR6 LOC115331551 PTHR11986:SF126 AMINOTRANSFERASE CLASS III ORNITHINE AMINOTRANSFERASE, MITOCHONDRIAL transferase activity#GO:0016740;catalytic activity#GO:0003824;transaminase activity#GO:0008483 proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;arginine metabolic process#GO:0006525;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739 transaminase#PC00216 IXOSC|EnsemblGenome=LOC120837061|UniProtKB=A0ACM8FL66 A0ACM8FL66 LOC120837061 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8041599|UniProtKB=A0ACM8DKR0 A0ACM8DKR0 LOC8041599 PTHR19853:SF0 WD REPEAT CONTAINING PROTEIN 3 WDR3 WD REPEAT-CONTAINING PROTEIN 3 RNA binding#GO:0003723;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8053527|UniProtKB=A0ACM8E3I2 A0ACM8E3I2 LOC8053527 PTHR24135:SF30 SH3 AND MULTIPLE ANKYRIN REPEAT DOMAINS PROTEIN LD13733P binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor complex adaptor activity#GO:0030159;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;signaling adaptor activity#GO:0035591;protein binding#GO:0005515 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;cell junction#GO:0030054;postsynapse#GO:0098794;dendritic spine#GO:0043197;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuron spine#GO:0044309;plasma membrane bounded cell projection#GO:0120025;dendrite#GO:0030425;postsynaptic membrane#GO:0045211;dendritic tree#GO:0097447;postsynaptic density#GO:0014069 scaffold/adaptor protein#PC00226 Ionotropic glutamate receptor pathway#P00037>PSD95#P00999 IXOSC|EnsemblGenome=LOC8029369|UniProtKB=A0ACM8G8X4 A0ACM8G8X4 Polr3E PTHR12069:SF0 DNA-DIRECTED RNA POLYMERASES III 80 KDA POLYPEPTIDE RNA POLYMERASE III SUBUNIT 5 DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC5 protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666 DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC8036621|UniProtKB=A0ACM8EWY7 A0ACM8EWY7 LOC8036621 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC121046466|UniProtKB=A0ACM8G217 A0ACM8G217 LOC121046466 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035631|UniProtKB=A0ACM8FCT6 A0ACM8FCT6 LOC8035631 PTHR16222:SF45 ADP-RIBOSYLGLYCOHYDROLASE DISEASE RESISTANCE R13L4_SHOC-2-LIKE LRR DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;hydrolase activity#GO:0016787 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115317165|UniProtKB=A0ACM8DWT3 A0ACM8DWT3 LOC115317165 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8031887|UniProtKB=A0ACM8DYA7 A0ACM8DYA7 LOC8031887 PTHR23235:SF139 KRUEPPEL-LIKE TRANSCRIPTION FACTOR HUCKEBEIN transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120838821|UniProtKB=A0ACM8ELE1 A0ACM8ELE1 LOC120838821 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8028971|UniProtKB=A0ACM8EI33 A0ACM8EI33 LOC8028971 PTHR48083:SF6 MEDIUM-CHAIN SPECIFIC ACYL-COA DEHYDROGENASE, MITOCHONDRIAL-RELATED ACYL-COA DEHYDROGENASE 6 catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;lipid modification#GO:0030258;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;fatty acid oxidation#GO:0019395 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120836811|UniProtKB=A0ACM8EGH4 A0ACM8EGH4 LOC120836811 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043682|UniProtKB=A0ACM8F0X5 A0ACM8F0X5 LOC8043682 PTHR19305:SF14 SYNAPTOSOMAL ASSOCIATED PROTEIN SYNAPTOSOMAL-ASSOCIATED PROTEIN-RELATED binding#GO:0005488;SNARE binding#GO:0000149;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;syntaxin binding#GO:0019905;SNAP receptor activity#GO:0005484;protein binding#GO:0005515 establishment of localization#GO:0051234;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;cell-cell signaling#GO:0007267;membrane organization#GO:0061024;biological regulation#GO:0065007;neurotransmitter secretion#GO:0007269;membrane fusion#GO:0061025;synaptic vesicle membrane organization#GO:0048499;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;synaptic vesicle fusion to presynaptic active zone membrane#GO:0031629;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;vesicle fusion#GO:0006906;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;exocytosis#GO:0006887;protein-containing complex organization#GO:0043933;vesicle organization#GO:0016050;cellular component organization or biogenesis#GO:0071840;vesicle-mediated transport in synapse#GO:0099003;exocytic process#GO:0140029;vesicle fusion to plasma membrane#GO:0099500;regulated exocytosis#GO:0045055;endomembrane system organization#GO:0010256;neurotransmitter transport#GO:0006836;organelle membrane fusion#GO:0090174;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;synaptic vesicle exocytosis#GO:0016079;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;synaptic signaling#GO:0099536;secretion by cell#GO:0032940;cellular localization#GO:0051641;export from cell#GO:0140352;signaling#GO:0023052;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796 SNARE protein#PC00034;membrane traffic protein#PC00150 Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;Alpha adrenergic receptor signaling pathway#P00002>SNARE#P00074;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;Adrenaline and noradrenaline biosynthesis#P00001>SNARE#P00072;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;Ionotropic glutamate receptor pathway#P00037>SNARE Complex#P01013;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Synaptic vesicle trafficking#P05734>SNAP-25#P05778;Metabotropic glutamate receptor group III pathway#P00039>SNARE Complex#P01042;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>SNARE Complex#P01066;Metabotropic glutamate receptor group II pathway#P00040>SNARE Complex#P01049 IXOSC|EnsemblGenome=LOC115314574|UniProtKB=A0ACM8F8M2 A0ACM8F8M2 LOC115314574 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transporter#PC00227 IXOSC|EnsemblGenome=LOC115329223|UniProtKB=A0ACM8EA74 A0ACM8EA74 LOC115329223 PTHR11685:SF371 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF14 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;transferase complex#GO:1990234 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8033523|UniProtKB=A0ACM8E723 A0ACM8E723 LOC8033523 PTHR24057:SF82 GLYCOGEN SYNTHASE KINASE-3 ALPHA PROTEIN KINASE SHAGGY-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;regulation of microtubule cytoskeleton organization#GO:0070507;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;regulation of microtubule-based process#GO:0032886;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;cell communication#GO:0007154;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Insulin/IGF pathway-protein kinase B signaling cascade#P00033>GSK-3#P00902;PDGF signaling pathway#P00047>GSK3#P01153;Angiogenesis#P00005>GSK3beta#P00211;Alzheimer disease-presenilin pathway#P00004>GSK-3beta#P00175 IXOSC|EnsemblGenome=LOC115325115|UniProtKB=A0ACM8F9V8 A0ACM8F9V8 LOC115325115 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8029595|UniProtKB=A0ACM8FYI2 A0ACM8FYI2 LOC8029595 PTHR21257:SF61 DELTA(14)-STEROL REDUCTASE LAMIN-B RECEPTOR catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;lipid biosynthetic process#GO:0008610;cholesterol biosynthetic process#GO:0006695;biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;small molecule biosynthetic process#GO:0044283;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;secondary alcohol biosynthetic process#GO:1902653;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;nuclear inner membrane#GO:0005637;nuclear membrane#GO:0031965;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;membrane#GO:0016020;organelle inner membrane#GO:0019866;nucleus#GO:0005634 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8026455|UniProtKB=A0ACM8DHT2 A0ACM8DHT2 Gart PTHR10520:SF12 TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3-RELATED TRIFUNCTIONAL PURINE BIOSYNTHETIC PROTEIN ADENOSINE-3 ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-nitrogen bonds#GO:0016879 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine nucleobase metabolic process#GO:0006144;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 De novo purine biosynthesis#P02738>Phosphoribosylamine glycine ligase#P02908 IXOSC|EnsemblGenome=LOC8052110|UniProtKB=A0ACM8DUC5 A0ACM8DUC5 LOC8052110 PTHR19282:SF551 TETRASPANIN TETRASPANIN-RELATED cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120842301|UniProtKB=A0ACM8EUJ7 A0ACM8EUJ7 LOC120842301 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121836174|UniProtKB=A0ACM8FXR9 A0ACM8FXR9 LOC121836174 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8034047|UniProtKB=A0ACM8DIT7 A0ACM8DIT7 LOC8034047 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120842635|UniProtKB=A0ACM8EU90 A0ACM8EU90 LOC120842635 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8032653|UniProtKB=A0ACM8FJD8 A0ACM8FJD8 mib1 PTHR24202:SF53 E3 UBIQUITIN-PROTEIN LIGASE MIB2 E3 UBIQUITIN-PROTEIN LIGASE MIB1 acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 signal transduction#GO:0007165;cellular process#GO:0009987;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;transport#GO:0006810;macromolecule metabolic process#GO:0043170;import into cell#GO:0098657;establishment of localization#GO:0051234;Notch signaling pathway#GO:0007219;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;endocytosis#GO:0006897;regulation of cellular process#GO:0050794;signaling#GO:0023052;protein modification by small protein conjugation or removal#GO:0070647;localization#GO:0051179;cell communication#GO:0007154;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120840229|UniProtKB=A0ACM8ENL3 A0ACM8ENL3 LOC120840229 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8051101|UniProtKB=A0ACM8EAT5 A0ACM8EAT5 Hacd1 PTHR11035:SF3 VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE VERY-LONG-CHAIN (3R)-3-HYDROXYACYL-COA DEHYDRATASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835 fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436 membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 dehydratase#PC00091 IXOSC|EnsemblGenome=LOC115331498|UniProtKB=A0ACM8EM96 A0ACM8EM96 LOC115331498 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051831|UniProtKB=A0ACM8EBJ7 A0ACM8EBJ7 LOC8051831 PTHR10465:SF6 TRANSMEMBRANE GTPASE FZO1 SARCALUMENIN IXOSC|EnsemblGenome=LOC8023478|UniProtKB=A0ACM8DPW9 A0ACM8DPW9 LOC8023478 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC8030773|UniProtKB=A0ACM8E6N3 A0ACM8E6N3 LOC8030773 PTHR32428:SF5 TARGET OF RAPAMYCIN COMPLEX 2 SUBUNIT BIT61-RELATED PROLINE-RICH PROTEIN 5-LIKE ISOFORM X1 enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 TORC2 signaling#GO:0038203;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;intracellular signal transduction#GO:0035556;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;TOR signaling#GO:0031929;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583 intracellular protein-containing complex#GO:0140535;TOR complex#GO:0038201;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8024836|UniProtKB=A0ACM8ECE1 A0ACM8ECE1 LOC8024836 PTHR46376:SF7 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 KELCH DOMAIN-CONTAINING PROTEIN 3 ISOFORM X1 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC120839992|UniProtKB=A0ACM8EP51 A0ACM8EP51 LOC120839992 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039559|UniProtKB=A0ACM8DYR0 A0ACM8DYR0 LOC8039559 PTHR43462:SF1 ALANYL-TRNA EDITING PROTEIN ALANYL-TRNA EDITING PROTEIN AARSD1 deacylase activity#GO:0160215;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101 regulation of biological quality#GO:0065008;biological regulation#GO:0065007 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121047559|UniProtKB=A0ACM8FHB4 A0ACM8FHB4 LOC121047559 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038895|UniProtKB=A0ACM8EE29 A0ACM8EE29 LOC8038895 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121836584|UniProtKB=A0ACM8G061 A0ACM8G061 LOC121836584 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036455|UniProtKB=A0ACM8E8S2 A0ACM8E8S2 LOC8036455 PTHR31531:SF2 E3 UBIQUITIN-PROTEIN LIGASE E3D FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE E3D ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;cyclin binding#GO:0030332;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115319185|UniProtKB=A0ACM8DYW4 A0ACM8DYW4 Sgf29 PTHR21539:SF0 SAGA-ASSOCIATED FACTOR 29 SAGA-ASSOCIATED FACTOR 29 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;SAGA-type complex#GO:0070461;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;SAGA complex#GO:0000124;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234 IXOSC|EnsemblGenome=LOC8039880|UniProtKB=A0ACM8E3D4 A0ACM8E3D4 PTHR45879:SF3 CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN B cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;intracellular signaling cassette#GO:0141124;regulation of nucleobase-containing compound metabolic process#GO:0019219 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 basic leucine zipper transcription factor#PC00056;DNA-binding transcription factor#PC00218 Transcription regulation by bZIP transcription factor#P00055>CREB#P01383;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713 IXOSC|EnsemblGenome=LOC115311847|UniProtKB=A0ACM8DRB4 A0ACM8DRB4 LOC115311847 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115326101|UniProtKB=A0ACM8E5J1 A0ACM8E5J1 LOC115326101 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8023926|UniProtKB=A0ACM8DHS3 A0ACM8DHS3 LOC8023926 PTHR12223:SF28 VESICULAR MANNOSE-BINDING LECTIN LECTIN, MANNOSE BINDING 1 LIKE carbohydrate binding#GO:0030246;monosaccharide binding#GO:0048029;binding#GO:0005488;small molecule binding#GO:0036094 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8029059|UniProtKB=A0ACM8EHS5 A0ACM8EHS5 LOC8029059 PTHR12763:SF28 FAMILY NOT NAMED GEO10507P1-RELATED IXOSC|EnsemblGenome=LOC121045782|UniProtKB=A0ACM8FAZ0 A0ACM8FAZ0 LOC121045782 PTHR10983:SF73 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cellular process#GO:0009987;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121832935|UniProtKB=A0ACM8FT44 A0ACM8FT44 LOC121832935 PTHR11804:SF84 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED SACCHAROLYSIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115320096|UniProtKB=A0ACM8FNG1 A0ACM8FNG1 PTHR11267:SF212 T-BOX PROTEIN-RELATED LP04777P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 developmental process#GO:0032502;cell fate specification#GO:0001708;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;heart development#GO:0007507;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;circulatory system development#GO:0072359;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 Rel homology transcription factor#PC00252;immunoglobulin fold transcription factor#PC00251 IXOSC|EnsemblGenome=LOC115331760|UniProtKB=A0ACM8ESC0 A0ACM8ESC0 LOC115331760 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115330847|UniProtKB=A0ACM8FR77 A0ACM8FR77 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121834292|UniProtKB=A0ACM8FQS2 A0ACM8FQS2 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323545|UniProtKB=A0ACM8F268 A0ACM8F268 LOC115323545 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121837505|UniProtKB=A0ACM8G525 A0ACM8G525 LOC121837505 PTHR12733:SF3 MITOCHONDRIAL ATP SYNTHASE B CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT B, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;proton channel activity#GO:0015252;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;ligase activity#GO:0016874;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate biosynthetic process#GO:1901293;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP biosynthetic process#GO:0006754;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;cellular process#GO:0009987 organelle membrane#GO:0031090;transporter complex#GO:1990351;proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;respiratory chain complex#GO:0098803;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796 primary active transporter#PC00068;ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC115327577|UniProtKB=A0ACM8E7W0 A0ACM8E7W0 LOC115327577 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8025531|UniProtKB=A0ACM8F490 A0ACM8F490 VhaAC45 PTHR12471:SF7 VACUOLAR ATP SYNTHASE SUBUNIT S1 V-TYPE PROTON ATPASE SUBUNIT S1 intracellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;biological regulation#GO:0065007;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cation-transporting ATPase complex#GO:0090533;membrane#GO:0016020;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494 primary active transporter#PC00068;ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC120837297|UniProtKB=A0ACM8EH20 A0ACM8EH20 LOC120837297 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8024168|UniProtKB=A0ACM8DYQ2 A0ACM8DYQ2 LOC8024168 PTHR31624:SF4 UPF0472 PROTEIN C16ORF72 HUWE1 ASSOCIATED PROTEIN MODIFYING STRESS RESPONSES IXOSC|EnsemblGenome=LOC115321878|UniProtKB=A0ACM8ELT2 A0ACM8ELT2 LOC115321878 PTHR45620:SF44 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTOR, ORPHAN-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8035895|UniProtKB=A0ACM8FIN6 A0ACM8FIN6 LOC8035895 PTHR45636:SF54 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED TWIN OF EYELESS, ISOFORM D RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 central nervous system development#GO:0007417;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;brain development#GO:0007420;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;head development#GO:0060322;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;regulation of gene expression#GO:0010468;sensory organ development#GO:0007423;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC115309531|UniProtKB=A0ACM8DNR7 A0ACM8DNR7 LOC115309531 PTHR24264:SF91 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120844939|UniProtKB=A0ACM8F045 A0ACM8F045 LOC120844939 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120847768|UniProtKB=A0ACM8F4T4 A0ACM8F4T4 LOC120847768 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115327800|UniProtKB=A0ACM8FI40 A0ACM8FI40 jar PTHR13140:SF870 MYOSIN MYOSIN HEAVY CHAIN 95F cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;microfilament motor activity#GO:0000146;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;actin filament-based movement#GO:0030048;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cell periphery#GO:0071944;membrane#GO:0016020;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;actin cytoskeleton#GO:0015629;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC120850222|UniProtKB=A0ACM8F8C7 A0ACM8F8C7 LOC120850222 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025560|UniProtKB=A0ACM8DJC0 A0ACM8DJC0 Snx3 PTHR45963:SF2 RE52028P SORTING NEXIN-3 IXOSC|EnsemblGenome=LOC8039566|UniProtKB=A0ACM8FXA4 A0ACM8FXA4 LOC8039566 PTHR11690:SF305 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sodium channel activity#GO:0005272;ligand-gated monoatomic cation channel activity#GO:0099094;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8041021|UniProtKB=A0ACM8E9X8 A0ACM8E9X8 LOC8041021 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115315561|UniProtKB=A0ACM8EHI9 A0ACM8EHI9 CstF50 PTHR44133:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 CLEAVAGE STIMULATION FACTOR SUBUNIT 1 nucleus#GO:0005634;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121836717|UniProtKB=A0ACM8FZI7 A0ACM8FZI7 LOC121836717 PTHR45659:SF24 HOMEOBOX PROTEIN HOX HOMEOTIC PROTEIN ANTENNAPEDIA-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120843930|UniProtKB=A0ACM8EX94 A0ACM8EX94 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115310039|UniProtKB=A0ACM8F2V2 A0ACM8F2V2 LOC115310039 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115309283|UniProtKB=A0ACM8DNG1 A0ACM8DNG1 LOC115309283 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029480|UniProtKB=A0ACM8ERF1 A0ACM8ERF1 LOC8029480 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115331096|UniProtKB=A0ACM8F3T5 A0ACM8F3T5 LOC115331096 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8025173|UniProtKB=A0ACM8EHK0 A0ACM8EHK0 LOC8025173 PTHR11863:SF241 STEROL DESATURASE FATTY ACID HYDROXYLASE DOMAIN-CONTAINING PROTEIN 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 oxidase#PC00175 IXOSC|EnsemblGenome=LOC8034812|UniProtKB=A0ACM8DPE9 A0ACM8DPE9 LOC8034812 PTHR44019:SF20 WD REPEAT-CONTAINING PROTEIN 55 WD REPEAT-CONTAINING PROTEIN 55 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8035311|UniProtKB=A0ACM8DJT3 A0ACM8DJT3 Srp9 PTHR12834:SF12 SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN SIGNAL RECOGNITION PARTICLE 9 KDA PROTEIN cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting#GO:0006605;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612;protein targeting to ER#GO:0045047;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121835725|UniProtKB=A0ACM8FVK2 A0ACM8FVK2 LOC121835725 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329374|UniProtKB=A0ACM8ERX3 A0ACM8ERX3 LOC115329374 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8042447|UniProtKB=A0ACM8DKU7 A0ACM8DKU7 LOC8042447 PTHR16082:SF2 AP-5 COMPLEX SUBUNIT MU-1 AP-5 COMPLEX SUBUNIT MU-1 transport#GO:0006810;intracellular transport#GO:0046907;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117;coated membrane#GO:0048475;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;vacuole#GO:0005773;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;cytosol#GO:0005829;AP-type membrane coat adaptor complex#GO:0030119;lytic vacuole#GO:0000323 IXOSC|EnsemblGenome=LOC8030240|UniProtKB=A0ACM8DGH8 A0ACM8DGH8 Sec63 PTHR24075:SF0 SEC63 DOMAIN-CONTAINING TRANSLOCATION PROTEIN SEC63 HOMOLOG RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605;post-translational protein targeting to endoplasmic reticulum membrane#GO:0006620;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting to membrane#GO:0006612;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;protein targeting to ER#GO:0045047 cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane protein complex#GO:0098796;rough endoplasmic reticulum membrane#GO:0030867;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;rough endoplasmic reticulum#GO:0005791;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120846209|UniProtKB=A0ACM8FH07 A0ACM8FH07 LOC120846209 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;microbody#GO:0042579 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC120841457|UniProtKB=A0ACM8ERJ2 A0ACM8ERJ2 PTHR24161:SF128 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PALMITOYLTRANSFERASE HIP14 palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 trans-synaptic signaling#GO:0099537;signal release#GO:0023061;secretion#GO:0046903;cellular localization#GO:0051641;cell communication#GO:0007154;localization#GO:0051179;secretion by cell#GO:0032940;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;export from cell#GO:0140352;regulated exocytosis#GO:0045055;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;vesicle-mediated transport in synapse#GO:0099003;establishment of localization#GO:0051234;exocytosis#GO:0006887;synaptic signaling#GO:0099536;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;synaptic vesicle exocytosis#GO:0016079;vesicle-mediated transport#GO:0016192;neurotransmitter secretion#GO:0007269;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;neurotransmitter transport#GO:0006836 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8040758|UniProtKB=A0ACM8DH30 A0ACM8DH30 LOC8040758 PTHR24243:SF237 G-PROTEIN COUPLED RECEPTOR PYROKININ-1 RECEPTOR neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8051709|UniProtKB=A0ACM8EKK8 A0ACM8EKK8 LOC8051709 PTHR11616:SF332 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;chloride transmembrane transporter activity#GO:0015108;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;sodium ion transport#GO:0006814;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;amino acid transport#GO:0006865;transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8035003|UniProtKB=A0ACM8E3H9 A0ACM8E3H9 okr PTHR45629:SF17 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54-LIKE DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 damaged DNA-binding protein#PC00086 IXOSC|EnsemblGenome=LOC120840396|UniProtKB=A0ACM8FWE6 A0ACM8FWE6 LOC120840396 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120843739|UniProtKB=A0ACM8EXW9 A0ACM8EXW9 LOC120843739 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8027904|UniProtKB=A0ACM8ECP6 A0ACM8ECP6 ClC-a PTHR45720:SF10 CHLORIDE CHANNEL PROTEIN 2 CHLORIDE CHANNEL PROTEIN 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;chloride channel activity#GO:0005254;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic anion channel activity#GO:0008308;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;voltage-gated channel activity#GO:0022832;monoatomic anion channel activity#GO:0005253 transport#GO:0006810;chloride transport#GO:0006821;monoatomic anion transport#GO:0006820;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;establishment of localization#GO:0051234;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC120849319|UniProtKB=A0ACM8F6M1 A0ACM8F6M1 LOC120849319 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840308|UniProtKB=A0ACM8EPQ1 A0ACM8EPQ1 LOC120840308 PTHR24238:SF83 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121834781|UniProtKB=A0ACM8FS12 A0ACM8FS12 LOC121834781 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030894|UniProtKB=A0ACM8ED23 A0ACM8ED23 LOC8030894 PTHR23340:SF0 ARGININE/SERINE RICH SPLICING FACTOR SF4/14 SURP AND G-PATCH DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120844395|UniProtKB=A0ACM8EZN6 A0ACM8EZN6 LOC120844395 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115310141|UniProtKB=A0ACM8FKS0 A0ACM8FKS0 LOC115310141 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837899|UniProtKB=A0ACM8EI29 A0ACM8EI29 LOC120837899 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841901|UniProtKB=A0ACM8ESD1 A0ACM8ESD1 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8042151|UniProtKB=A0ACM8FWX3 A0ACM8FWX3 LOC8042151 PTHR10048:SF111 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 3-KINASE AGE-1 phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773 glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;organophosphate metabolic process#GO:0019637;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;cell motility#GO:0048870;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phosphatidylinositol phosphate biosynthetic process#GO:0046854;intracellular signal transduction#GO:0035556;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154 cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;extrinsic component of membrane#GO:0019898 kinase#PC00137 Angiogenesis#P00005>PI3K#P00236;Endothelin signaling pathway#P00019>PI3K#P00577;p53 pathway#P00059>PI3K#P04609;EGF receptor signaling pathway#P00018>PI3K#P00557;Hypoxia response via HIF activation#P00030>PI3K#P00823;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Ras Pathway#P04393>PI3K#P04567;p53 pathway feedback loops 2#P04398>PI3K#P04661;FGF signaling pathway#P00021>PI3K#P00640;Integrin signalling pathway#P00034>PI3K#P00936;VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363 IXOSC|EnsemblGenome=LOC8036077|UniProtKB=A0ACM8DXE3 A0ACM8DXE3 Set PTHR11875:SF49 TESTIS-SPECIFIC Y-ENCODED PROTEIN PROTEIN SET protein binding#GO:0005515;histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8043805|UniProtKB=A0ACM8DGY2 A0ACM8DGY2 PTHR22572:SF104 SUGAR-1-PHOSPHATE GUANYL TRANSFERASE MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE REGULATORY SUBUNIT ALPHA transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 Mannose metabolism#P02752>Mannose 1-P guanylyl transferase#P03018 IXOSC|EnsemblGenome=LOC8050749|UniProtKB=A0ACM8DLT2 A0ACM8DLT2 LOC8050749 PTHR10656:SF70 CELL FATE DETERMINING PROTEIN MAB21-RELATED PROTEIN MAB-21-LIKE transferase#PC00220;nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC8053590|UniProtKB=A0ACM8ESU7 A0ACM8ESU7 LOC8053590 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115324228|UniProtKB=A0ACM8EW00 A0ACM8EW00 LOC115324228 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115331623|UniProtKB=A0ACM8F0P9 A0ACM8F0P9 LOC115331623 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120838024|UniProtKB=A0ACM8EJP7 A0ACM8EJP7 LOC120838024 PTHR36943:SF2 CCHC-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042882|UniProtKB=A0ACM8FUM0 A0ACM8FUM0 LOC8042882 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120850531|UniProtKB=A0ACM8FA73 A0ACM8FA73 LOC120850531 PTHR21348:SF4 FAMILY NOT NAMED SULFIREDOXIN-1 oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;cellular response to oxidative stress#GO:0034599;response to stimulus#GO:0050896;response to chemical#GO:0042221;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC115333165|UniProtKB=A0ACM8EEL3 A0ACM8EEL3 Usp12-46 PTHR24006:SF733 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 12_46 HOMOLOG deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 regulation of biological quality#GO:0065008;biological regulation#GO:0065007;regulation of protein stability#GO:0031647 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8050986|UniProtKB=A0ACM8E596 A0ACM8E596 LOC8050986 PTHR23424:SF34 SERUM AMYLOID A LD40680P intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 apolipoprotein#PC00052;transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121835877|UniProtKB=A0ACM8FW67 A0ACM8FW67 LOC121835877 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326062|UniProtKB=A0ACM8E650 A0ACM8E650 Chrac-16 PTHR10252:SF153 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED CHROMATIN ACCESSIBILITY COMPLEX PROTEIN 1 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA replication#GO:0006260;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139 ISWI-type complex#GO:0031010;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleus#GO:0005634;chromatin#GO:0000785 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8028385|UniProtKB=A0ACM8EIY7 A0ACM8EIY7 LOC8028385 PTHR11532:SF96 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D-LIKE PROTEIN peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 IXOSC|EnsemblGenome=LOC115330848|UniProtKB=A0ACM8ECD2 A0ACM8ECD2 LOC115330848 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115313089|UniProtKB=A0ACM8DSE8 A0ACM8DSE8 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331968|UniProtKB=A0ACM8EDN7 A0ACM8EDN7 LOC115331968 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121835898|UniProtKB=A0ACM8FXE5 A0ACM8FXE5 LOC121835898 PTHR47969:SF15 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;microtubule motor activity#GO:0003777;isomerase activity#GO:0016853;cytoskeletal motor activity#GO:0003774 microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;cellular process#GO:0009987;organelle organization#GO:0006996 organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 microtubule binding motor protein#PC00156;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8036017|UniProtKB=A0ACM8DWQ5 A0ACM8DWQ5 PTHR23280:SF21 4.1 G PROTEIN PROTEIN 4.1 HOMOLOG cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC8027264|UniProtKB=A0ACM8DIW4 A0ACM8DIW4 LOC8027264 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115325646|UniProtKB=A0ACM8EZ99 A0ACM8EZ99 LOC115325646 PTHR23301:SF106 CHITIN BINDING PERITROPHIN-A CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8039071|UniProtKB=A0ACM8DK82 A0ACM8DK82 LOC8039071 PTHR23235:SF164 KRUEPPEL-LIKE TRANSCRIPTION FACTOR CABUT, ISOFORM A sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8023845|UniProtKB=A0ACM8DW16 A0ACM8DW16 LOC8023845 PTHR10629:SF61 CYTOSINE-SPECIFIC METHYLTRANSFERASE DNA (CYTOSINE-5)-METHYLTRANSFERASE 1 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on DNA#GO:0140097;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA methyltransferase#PC00013 IXOSC|EnsemblGenome=LOC8030152|UniProtKB=A0ACM8DJC3 A0ACM8DJC3 LOC8030152 PTHR13177:SF4 DEATH-ASSOCIATED PROTEIN 1 GEO09647P1 binding#GO:0005488;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of gene expression#GO:0010629;regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;negative regulation of translation#GO:0017148;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;apoptotic signaling pathway#GO:0097190;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of autophagy#GO:0010507;programmed cell death#GO:0012501;cell death#GO:0008219;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;cell communication#GO:0007154;negative regulation of catabolic process#GO:0009895 IXOSC|EnsemblGenome=LOC120845311|UniProtKB=A0ACM8G6I2 A0ACM8G6I2 LOC121838069 PTHR46599:SF9 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED 4-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115308871|UniProtKB=A0ACM8DN42 A0ACM8DN42 mon2 PTHR10663:SF333 GUANYL-NUCLEOTIDE EXCHANGE FACTOR PROTEIN MON2 HOMOLOG localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;protein localization to vacuole#GO:0072665;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;cytosolic transport#GO:0016482;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;vacuolar transport#GO:0007034;intracellular protein transport#GO:0006886;transport#GO:0006810;vesicle-mediated transport#GO:0016192;retrograde transport, endosome to Golgi#GO:0042147;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;membrane#GO:0016020;vesicle membrane#GO:0012506 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC115331660|UniProtKB=A0ACM8EDB3 A0ACM8EDB3 LOC115331660 PTHR24338:SF14 HOMEOBOX PROTEIN MSX HOMEOBOX DOMAIN-CONTAINING PROTEIN homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC121837508|UniProtKB=A0ACM8G4R5 A0ACM8G4R5 LOC121837508 PTHR13651:SF1 PROTEIN ABITRAM PROTEIN ABITRAM actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin monomer binding#GO:0003785;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cell morphogenesis#GO:0000902;regulation of plasma membrane bounded cell projection assembly#GO:0120032;regulation of cellular component organization#GO:0051128;cell differentiation#GO:0030154;cell projection organization#GO:0030030;regulation of cellular component biogenesis#GO:0044087;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;dendrite development#GO:0016358;neuron development#GO:0048666;regulation of biological quality#GO:0065008;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of actin filament length#GO:0030832;regulation of actin cytoskeleton organization#GO:0032956;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;regulation of anatomical structure size#GO:0090066;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;dendrite morphogenesis#GO:0048813;regulation of supramolecular fiber organization#GO:1902903;anatomical structure development#GO:0048856;regulation of cell projection assembly#GO:0060491;system development#GO:0048731;multicellular organismal process#GO:0032501;regulation of actin filament polymerization#GO:0030833;plasma membrane bounded cell projection organization#GO:0120036;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament organization#GO:0110053;cellular developmental process#GO:0048869;regulation of plasma membrane bounded cell projection organization#GO:0120035;neurogenesis#GO:0022008;regulation of filopodium assembly#GO:0051489;regulation of actin filament-based process#GO:0032970;regulation of cell projection organization#GO:0031344;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502 intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;filopodium#GO:0030175;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;nucleus#GO:0005634;neuron projection#GO:0043005;cell leading edge#GO:0031252;intracellular membraneless organelle#GO:0043232;somatodendritic compartment#GO:0036477;lamellipodium#GO:0030027 IXOSC|EnsemblGenome=LOC8035849|UniProtKB=A0ACM8E494 A0ACM8E494 LOC8035849 PTHR12243:SF75 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115327320|UniProtKB=A0ACM8E7J7 A0ACM8E7J7 PTHR24072:SF398 RHO FAMILY GTPASE RAS-LIKE GTP-BINDING PROTEIN RHO1 purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of organelle organization#GO:0033043;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;actin cytoskeleton organization#GO:0030036;cell motility#GO:0048870;regulation of cellular process#GO:0050794;signaling#GO:0023052;actin filament-based process#GO:0030029;cell communication#GO:0007154;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;signal transduction#GO:0007165;cellular process#GO:0009987;cell migration#GO:0016477;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944 small GTPase#PC00208;G-protein#PC00020 Ras Pathway#P04393>Rho#P04578;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507 IXOSC|EnsemblGenome=LOC8031012|UniProtKB=A0ACM8ELV4 A0ACM8ELV4 LOC8031012 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8038969|UniProtKB=A0ACM8DWK2 A0ACM8DWK2 LOC8038969 PTHR11630:SF47 DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER DNA REPLICATION LICENSING FACTOR REC cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8030225|UniProtKB=A0ACM8DSQ6 A0ACM8DSQ6 LOC8030225 PTHR45418:SF8 CANCER/TESTIS ANTIGEN 55 RNA HELICASE MOV10L1 IXOSC|EnsemblGenome=LOC115317556|UniProtKB=A0ACM8DXN3 A0ACM8DXN3 LOC115317556 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328022|UniProtKB=A0ACM8F813 A0ACM8F813 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025482|UniProtKB=A0ACM8DJA5 A0ACM8DJA5 LOC8025482 PTHR33562:SF27 ATILLA, ISOFORM B-RELATED-RELATED FI02817P-RELATED IXOSC|EnsemblGenome=LOC121835469|UniProtKB=A0ACM8FU57 A0ACM8FU57 LOC121835469 PTHR36943:SF3 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031952|UniProtKB=A0ACM8EEU4 A0ACM8EEU4 LOC8031952 PTHR12460:SF0 CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN CID DOMAIN-CONTAINING PROTEIN-RELATED protein binding#GO:0005515;RNA polymerase II complex binding#GO:0000993;RNA polymerase core enzyme binding#GO:0043175;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 protein-binding activity modulator#PC00095;kinase inhibitor#PC00139 IXOSC|EnsemblGenome=LOC115319536|UniProtKB=A0ACM8DZX2 A0ACM8DZX2 LOC115319536 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8042435|UniProtKB=A0ACM8DTT8 A0ACM8DTT8 LOC8042435 PTHR23048:SF66 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN 2 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8039865|UniProtKB=A0ACM8DWY3 A0ACM8DWY3 LOC8039865 PTHR47679:SF3 PROTEIN TORNADO 1 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115320083|UniProtKB=A0ACM8FLH9 A0ACM8FLH9 LOC115320083 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8050775|UniProtKB=A0ACM8E780 A0ACM8E780 LOC8050775 PTHR31735:SF1 VACUOLAR MEMBRANE PROTEIN YPL162C VACUOLAR MEMBRANE PROTEIN YPL162C membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120841758|UniProtKB=A0ACM8G5F5 A0ACM8G5F5 LOC120841758 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032087|UniProtKB=A0ACM8FUW5 A0ACM8FUW5 LOC8032087 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC121837211|UniProtKB=A0ACM8G2T9 A0ACM8G2T9 LOC121837211 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120843138|UniProtKB=A0ACM8EVA8 A0ACM8EVA8 LOC120843138 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115311474|UniProtKB=A0ACM8DQT7 A0ACM8DQT7 LOC115311474 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121835751|UniProtKB=A0ACM8FUZ9 A0ACM8FUZ9 LOC121835751 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120851077|UniProtKB=A0ACM8FBE1 A0ACM8FBE1 LOC120851077 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8040437|UniProtKB=A0ACM8F3D7 A0ACM8F3D7 LOC8040437 PTHR45729:SF4 RABPHILIN, ISOFORM A RAB EFFECTOR NOC2 biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of secretion by cell#GO:1903532;positive regulation of cellular process#GO:0048522;regulation of vesicle-mediated transport#GO:0060627;positive regulation of transport#GO:0051050;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;regulation of secretion#GO:0051046;positive regulation of secretion#GO:0051047 IXOSC|EnsemblGenome=LOC8032009|UniProtKB=A0ACM8DJ28 A0ACM8DJ28 LOC8032009 PTHR44090:SF1 WD REPEAT-CONTAINING PROTEIN 61 SUPERKILLER COMPLEX PROTEIN 8 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115330265|UniProtKB=A0ACM8FIM9 A0ACM8FIM9 LOC115330265 PTHR24346:SF112 MAP/MICROTUBULE AFFINITY-REGULATING KINASE TESTIS-SPECIFIC SERINE_THREONINE-PROTEIN KINASE 1 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;microtubule cytoskeleton organization#GO:0000226;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121837261|UniProtKB=A0ACM8G300 A0ACM8G300 LOC121837261 PTHR24238:SF57 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR 83 neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;neuropeptide signaling pathway#GO:0007218;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121837563|UniProtKB=A0ACM8G5B2 A0ACM8G5B2 LOC121837563 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC121048059|UniProtKB=A0ACM8FHH7 A0ACM8FHH7 LOC121048059 PTHR45080:SF8 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE 1 ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell junction organization#GO:0034330;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;synapse organization#GO:0050808;cell adhesion#GO:0007155 axon#GO:0030424;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cell body#GO:0044297 IXOSC|EnsemblGenome=LOC115316820|UniProtKB=A0ACM8DWG0 A0ACM8DWG0 LOC115316820 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC121833187|UniProtKB=A0ACM8FJJ8 A0ACM8FJJ8 LOC121833187 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033729|UniProtKB=A0ACM8F094 A0ACM8F094 RhoBTB PTHR24072:SF156 RHO FAMILY GTPASE RHO-RELATED BTB DOMAIN CONTAINING, ISOFORM B GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;protein kinase binding#GO:0019901;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;kinase binding#GO:0019900;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 actin filament-based process#GO:0030029;cortical cytoskeleton organization#GO:0030865;establishment or maintenance of cell polarity#GO:0007163;regulation of biological quality#GO:0065008;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of cell shape#GO:0008360;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of developmental process#GO:0050793;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of actin filament-based process#GO:0032970;actin filament organization#GO:0007015;regulation of anatomical structure morphogenesis#GO:0022603;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007 intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC115308268|UniProtKB=A0ACM8DMB3 A0ACM8DMB3 LOC115308268 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024616|UniProtKB=A0ACM8EE62 A0ACM8EE62 LOC8024616 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8033679|UniProtKB=A0ACM8DI55 A0ACM8DI55 LOC8033679 PTHR46359:SF2 GEO07743P1 GEO07743P1 IXOSC|EnsemblGenome=LOC120846753|UniProtKB=A0ACM8F345 A0ACM8F345 LOC120846753 PTHR12349:SF2 ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2 PALMITOYLTRANSFERASE ZDHHC8 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 IXOSC|EnsemblGenome=LOC8038522|UniProtKB=A0ACM8DZA7 A0ACM8DZA7 LOC8038522 PTHR48068:SF4 TAF9 RNA POLYMERASE II, TATA BOX-BINDING PROTEIN (TBP)-ASSOCIATED FACTOR TATA-BOX BINDING PROTEIN ASSOCIATED FACTOR 9 structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;protein-DNA complex assembly#GO:0065004;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 chromatin#GO:0000785;SAGA complex#GO:0000124;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;histone acetyltransferase complex#GO:0000123;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;acetyltransferase complex#GO:1902493;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;peptidase complex#GO:1905368;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;nuclear DNA-directed RNA polymerase complex#GO:0055029;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461 Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription regulation#P00023>TBP-associated factors#P00658 IXOSC|EnsemblGenome=LOC8028596|UniProtKB=A0ACM8F4M5 A0ACM8F4M5 LOC8028596 PTHR23199:SF18 NEUROTROPHIN 1-RELATED PROTEIN SPAETZLE-RELATED growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515 anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;central nervous system development#GO:0007417;response to stimulus#GO:0050896;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;anatomical structure morphogenesis#GO:0009653;innate immune response#GO:0045087;multicellular organism development#GO:0007275;defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;response to external stimulus#GO:0009605;developmental process#GO:0032502;multicellular organismal process#GO:0032501;defense response to other organism#GO:0098542;response to other organism#GO:0051707;nervous system development#GO:0007399;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response to symbiont#GO:0140546;immune response#GO:0006955 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Toll pathway-drosophila#P06217>SPZ#P06349;Toll pathway-drosophila#P06217>SPZ full length#P06347 IXOSC|EnsemblGenome=LOC8037928|UniProtKB=A0ACM8DIC5 A0ACM8DIC5 mof PTHR10615:SF82 HISTONE ACETYLTRANSFERASE HISTONE ACETYLTRANSFERASE KAT8 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone acetyltransferase activity#GO:0004402;histone modifying activity#GO:0140993;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746 transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;NuA4 histone acetyltransferase complex#GO:0035267;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;NSL complex#GO:0044545;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115310662|UniProtKB=A0ACM8DQ04 A0ACM8DQ04 PTHR11254:SF429 HECT DOMAIN UBIQUITIN-PROTEIN LIGASE E3 UBIQUITIN-PROTEIN LIGASE SU(DX) catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8041094|UniProtKB=A0ACM8DKM4 A0ACM8DKM4 mts PTHR45619:SF12 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE PP2A phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824 cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein phosphatase#PC00195;protein modifying enzyme#PC00260 p53 pathway feedback loops 2#P04398>PP2A-C#P04659;Wnt signaling pathway#P00057>PP2A#P01438;FGF signaling pathway#P00021>PP2A#P00629;p53 pathway#P00059>PP2A#P04630;EGF receptor signaling pathway#P00018>PP2A#P00547;p53 pathway by glucose deprivation#P04397>PP2A-C#P04643 IXOSC|EnsemblGenome=LOC8031259|UniProtKB=A0ACM8DZT1 A0ACM8DZT1 LOC8031259 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER FI24011P1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115322047|UniProtKB=A0ACM8EXY6 A0ACM8EXY6 LOC115322047 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8025299|UniProtKB=A0ACM8DX93 A0ACM8DX93 Cdk12 PTHR24056:SF597 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 12 catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of transcription elongation by RNA polymerase II#GO:0034243;regulation of DNA-templated transcription elongation#GO:0032784;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of DNA-templated transcription, elongation#GO:0032786 organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120848077|UniProtKB=A0ACM8F4B4 A0ACM8F4B4 LOC120848077 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121046097|UniProtKB=A0ACM8FD46 A0ACM8FD46 LOC121046097 PTHR45902:SF3 LATROPHILIN RECEPTOR-LIKE PROTEIN A METHUSELAH 15-LIKE PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115315214|UniProtKB=A0ACM8EZV4 A0ACM8EZV4 LOC115315214 PTHR33776:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834306|UniProtKB=A0ACM8FNI3 A0ACM8FNI3 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838397|UniProtKB=A0ACM8DUA3 A0ACM8DUA3 LOC8040305 PTHR47960:SF17 DEAD-BOX ATP-DEPENDENT RNA HELICASE 50 ATP-DEPENDENT RNA HELICASE DDX6-RELATED RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 negative regulation of translation#GO:0017148;organelle assembly#GO:0070925;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;cytoplasmic stress granule assembly#GO:0034063;regulation of macromolecule metabolic process#GO:0060255;P-body assembly#GO:0033962;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular component biogenesis#GO:0044085;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115314013|UniProtKB=A0ACM8ETE7 A0ACM8ETE7 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8054079|UniProtKB=A0ACM8EB66 A0ACM8EB66 LOC8054079 PTHR13608:SF3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 ARMADILLO-LIKE HELICAL DOMAIN-CONTAINING PROTEIN 3 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8031487|UniProtKB=A0ACM8EE98 A0ACM8EE98 Sod1 PTHR10003:SF71 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN]-RELATED catalytic activity#GO:0003824;copper ion binding#GO:0005507;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 cellular response to stimulus#GO:0051716;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular detoxification#GO:1990748;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;response to stress#GO:0006950;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;response to reactive oxygen species#GO:0000302;superoxide metabolic process#GO:0006801;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837144|UniProtKB=A0ACM8EGC5 A0ACM8EGC5 LOC120837144 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121835214|UniProtKB=A0ACM8FRZ9 A0ACM8FRZ9 LOC121835214 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034777|UniProtKB=A0ACM8DZN8 A0ACM8DZN8 LOC8034777 PTHR10887:SF550 DNA2/NAM7 HELICASE FAMILY HELICASE SEN1 N-TERMINAL DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;cytosol#GO:0005829;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8041319|UniProtKB=A0ACM8FZX2 A0ACM8FZX2 LOC8041319 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121834679|UniProtKB=A0ACM8FRL5 A0ACM8FRL5 PTHR28052:SF1 UPF0545 PROTEIN C22ORF39 SYNAPTIC PLASTICITY REGULATOR PANTS IXOSC|EnsemblGenome=LOC115322298|UniProtKB=A0ACM8FQ61 A0ACM8FQ61 LOC115322298 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043890|UniProtKB=A0ACM8DWX4 A0ACM8DWX4 LOC8043890 PTHR46117:SF3 FI24210P1 FI24210P1 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8027820|UniProtKB=A0ACM8DNT1 A0ACM8DNT1 LOC8027820 PTHR10160:SF19 NAD(P) TRANSHYDROGENASE NAD(P) TRANSHYDROGENASE, MITOCHONDRIAL heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;purine nucleotide binding#GO:0017076;small molecule binding#GO:0036094 NADP+ metabolic process#GO:0006739;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing small molecule metabolic process#GO:0055086;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;NADPH regeneration#GO:0006740;pyridine-containing compound metabolic process#GO:0072524;nucleotide metabolic process#GO:0009117 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121833099|UniProtKB=A0ACM8FI80 A0ACM8FI80 LOC121833099 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115326984|UniProtKB=A0ACM8FHW1 A0ACM8FHW1 LOC115326984 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8051999|UniProtKB=A0ACM8E0G2 A0ACM8E0G2 LOC8051999 PTHR43899:SF40 RH59310P INACTIVE HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 1 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120837613|UniProtKB=A0ACM8EIV2 A0ACM8EIV2 LOC120837614 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC8023266|UniProtKB=A0ACM8E7D5 A0ACM8E7D5 Tif-IA PTHR12790:SF0 TRANSCRIPTION INITIATION FACTOR IA RRN3 RNA POLYMERASE I-SPECIFIC TRANSCRIPTION INITIATION FACTOR RRN3-RELATED DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;DNA-templated transcription initiation#GO:0006352;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;transcription initiation at RNA polymerase I promoter#GO:0006361;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 General transcription by RNA polymerase I#P00022>RNA Polymerase I Complex#P00652 IXOSC|EnsemblGenome=LOC8050455|UniProtKB=A0ACM8DV12 A0ACM8DV12 LOC8050455 PTHR43908:SF3 AT29763P-RELATED AT29763P-RELATED protein binding#GO:0005515;Hsp70 protein binding#GO:0030544;protein-folding chaperone binding#GO:0051087;binding#GO:0005488;heat shock protein binding#GO:0031072 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;cellular response to misfolded protein#GO:0071218;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;response to misfolded protein#GO:0051788;protein folding#GO:0006457;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 IXOSC|EnsemblGenome=LOC8039476|UniProtKB=A0ACM8EEC1 A0ACM8EEC1 LOC8039476 PTHR15678:SF6 ANTIGEN MLAA-22-RELATED BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2 IXOSC|EnsemblGenome=LOC8024684|UniProtKB=A0ACM8DVQ7 A0ACM8DVQ7 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115324688|UniProtKB=A0ACM8FKR4 A0ACM8FKR4 LOC115324688 PTHR13124:SF12 39S RIBOSOMAL PROTEIN L46, MITOCHONDRIAL PRECURSOR-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN ML46 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115315085|UniProtKB=A0ACM8EI27 A0ACM8EI27 Art1 PTHR11006:SF124 PROTEIN ARGININE N-METHYLTRANSFERASE ARGININE METHYLTRANSFERASE 9-RELATED histone modifying activity#GO:0140993;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8039608|UniProtKB=A0ACM8G3H0 A0ACM8G3H0 LOC8039608 PTHR24058:SF12 DUAL SPECIFICITY PROTEIN KINASE DUAL SPECIFICITY TYROSINE-PHOSPHORYLATION-REGULATED KINASE 1B kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115318285|UniProtKB=A0ACM8FWT1 A0ACM8FWT1 LOC115318285 PTHR46118:SF4 PROTEIN ABHD11 SN-1-SPECIFIC DIACYLGLYCEROL LIPASE ABHD11 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120844181|UniProtKB=A0ACM8EY49 A0ACM8EY49 LOC120844181 PTHR12463:SF1 OXYGENASE-RELATED 2-OXOGLUTARATE AND FE-DEPENDENT OXYGENASE FAMILY PROTEIN oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120840821|UniProtKB=A0ACM8EQB8 A0ACM8EQB8 LOC120840821 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8039829|UniProtKB=A0ACM8E3A0 A0ACM8E3A0 LOC8039829 PTHR35578:SF6 PROLINE-RICH TRANSMEMBRANE PROTEIN 4-RELATED PROLINE-RICH TRANSMEMBRANE PROTEIN 4 IXOSC|EnsemblGenome=LOC121836519|UniProtKB=A0ACM8G0A4 A0ACM8G0A4 LOC121836519 PTHR43767:SF1 LONG-CHAIN-FATTY-ACID--COA LIGASE NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC115316865|UniProtKB=A0ACM8F659 A0ACM8F659 LOC115316865 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120849530|UniProtKB=A0ACM8F8Y0 A0ACM8F8Y0 LOC120849530 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC115323074|UniProtKB=A0ACM8E2P3 A0ACM8E2P3 LOC115323074 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8051521|UniProtKB=A0ACM8EX19 A0ACM8EX19 LOC8051521 PTHR24256:SF579 TRYPTASE-RELATED WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120846959|UniProtKB=A0ACM8F3K4 A0ACM8F3K4 LOC120846959 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8030156|UniProtKB=A0ACM8DJB5 A0ACM8DJB5 LOC8030156 PTHR12948:SF3 NEDD8 ULTIMATE BUSTER-1 BS4 PROTEIN NEDD8 ULTIMATE BUSTER 1 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of catabolic process#GO:0009894;regulation of protein catabolic process#GO:0042176 IXOSC|EnsemblGenome=LOC8043963|UniProtKB=A0ACM8DL66 A0ACM8DL66 LOC8043963 PTHR32094:SF5 FANCONI ANEMIA GROUP E PROTEIN FANCONI ANEMIA GROUP E PROTEIN nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;Fanconi anaemia nuclear complex#GO:0043240;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8040582|UniProtKB=A0ACM8DSX7 A0ACM8DSX7 LOC8040582 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120849110|UniProtKB=A0ACM8G7A9 A0ACM8G7A9 LOC120849110 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8039104|UniProtKB=A0ACM8DQ85 A0ACM8DQ85 PTHR16195:SF16 ZINC FINGER CCHC DOMAIN CONTAINING PROTEIN ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 14 IXOSC|EnsemblGenome=LOC120849512|UniProtKB=A0ACM8DLP6 A0ACM8DLP6 LOC120849512 PTHR11893:SF40 INNEXIN INNEXIN SHAKING-B wide pore channel activity#GO:0022829;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 gap junction#PC00105 IXOSC|EnsemblGenome=LOC121833609|UniProtKB=A0ACM8FKK8 A0ACM8FKK8 LOC121833609 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026042|UniProtKB=A0ACM8E0W5 A0ACM8E0W5 LOC8026042 PTHR24198:SF196 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ZU5 DOMAIN-CONTAINING PROTEIN intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120838581|UniProtKB=A0ACM8EJJ6 A0ACM8EJJ6 LOC120838581 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC115329501|UniProtKB=A0ACM8EAI1 A0ACM8EAI1 LOC115329501 PTHR42643:SF49 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC RECEPTOR transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8034149|UniProtKB=A0ACM8EEQ3 A0ACM8EEQ3 Ube3a PTHR45700:SF8 UBIQUITIN-PROTEIN LIGASE E3C UBIQUITIN-PROTEIN LIGASE E3A protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E3#P01490;EGF receptor signaling pathway#P00018>RKIP#P00548 IXOSC|EnsemblGenome=LOC8036413|UniProtKB=A0ACM8FTH6 A0ACM8FTH6 LOC8036413 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8053304|UniProtKB=A0ACM8DL65 A0ACM8DL65 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121046075|UniProtKB=A0ACM8FBS7 A0ACM8FBS7 LOC121046075 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837194|UniProtKB=A0ACM8G2Q5 A0ACM8G2Q5 LOC121837194 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8040280|UniProtKB=A0ACM8DKH6 A0ACM8DKH6 LOC8040280 PTHR24238:SF47 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115313172|UniProtKB=A0ACM8DST9 A0ACM8DST9 LOC115313172 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8051457|UniProtKB=A0ACM8DQ53 A0ACM8DQ53 LOC8051457 PTHR11960:SF18 EUKARYOTIC TRANSLATION INITIATION FACTOR 4E RELATED EUKARYOTIC TRANSLATION INITIATION FACTOR 4E HOMOLOGOUS PROTEIN, ISOFORM B translation initiation factor activity#GO:0003743;RNA binding#GO:0003723;translation factor activity#GO:0180051;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC115316630|UniProtKB=A0ACM8FTA4 A0ACM8FTA4 LOC115316630 PTHR11177:SF410 CHITINASE HISTIDINE-RICH CARBOXYL TERMINUS PROTEIN 1 ISOFORM X1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;aminoglycan catabolic process#GO:0006026;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041047|UniProtKB=A0ACM8EFD6 A0ACM8EFD6 LOC8041047 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115321262|UniProtKB=A0ACM8E0Z6 A0ACM8E0Z6 LOC115321262 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115317193|UniProtKB=A0ACM8F3B2 A0ACM8F3B2 LOC115317193 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8029625|UniProtKB=A0ACM8E2C3 A0ACM8E2C3 LOC8029625 PTHR43333:SF1 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8043692|UniProtKB=A0ACM8FJ29 A0ACM8FJ29 LOC8043692 PTHR24049:SF22 CRUMBS FAMILY MEMBER DELTA-LIKE PROTEIN cellular process#GO:0009987;heterophilic cell-cell adhesion#GO:0007157;cell-cell adhesion#GO:0098609;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8036651|UniProtKB=A0ACM8EPL5 A0ACM8EPL5 LOC8036651 PTHR11351:SF21 ACYL-COA DESATURASE GH07782P-RELATED metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;unsaturated fatty acid metabolic process#GO:0033559;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;unsaturated fatty acid biosynthetic process#GO:0006636;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;oxoacid metabolic process#GO:0043436;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC8041828|UniProtKB=A0ACM8EER4 A0ACM8EER4 LOC8041828 PTHR13531:SF0 GEO07735P1-RELATED-RELATED GEO07735P1-RELATED organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036 cilium#GO:0005929;ciliary transition zone#GO:0035869;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115310677|UniProtKB=A0ACM8F527 A0ACM8F527 LOC115310677 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040009|UniProtKB=A0ACM8F710 A0ACM8F710 LOC8040009 PTHR11730:SF60 AMMONIUM TRANSPORTER RH50, ISOFORM D channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 homeostatic process#GO:0042592;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;chemical homeostasis#GO:0048878 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC115316224|UniProtKB=A0ACM8F2Y2 A0ACM8F2Y2 LOC115316224 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039504|UniProtKB=A0ACM8DNP7 A0ACM8DNP7 PTHR19818:SF178 ZINC FINGER PROTEIN ZIC AND GLI PAIR-RULE PROTEIN ODD-PAIRED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120843090|UniProtKB=A0ACM8EVB1 A0ACM8EVB1 LOC120843090 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121047413|UniProtKB=A0ACM8FKJ3 A0ACM8FKJ3 LOC121047413 PTHR31815:SF1 AGAP005329-PA TRANSMEMBRANE PROTEIN 200C IXOSC|EnsemblGenome=LOC8035681|UniProtKB=A0ACM8EWV6 A0ACM8EWV6 LOC8035681 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8026479|UniProtKB=A0ACM8DUY8 A0ACM8DUY8 LOC8026479 PTHR21641:SF0 TRANSLATION INITIATION FACTOR-RELATED RNA-BINDING PROTEIN EIF1AD-RELATED nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC8030433|UniProtKB=A0ACM8DH35 A0ACM8DH35 LOC8030433 PTHR23110:SF118 BTB DOMAIN TRANSCRIPTION FACTOR PROTEIN TRAMTRACK, ALPHA ISOFORM regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8041985|UniProtKB=A0ACM8E3C4 A0ACM8E3C4 LOC8041985 PTHR46468:SF1 SENTRIN-SPECIFIC PROTEASE 8 SENTRIN-SPECIFIC PROTEASE 8 peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170 protease#PC00190 IXOSC|EnsemblGenome=LOC115332727|UniProtKB=A0ACM8EX58 A0ACM8EX58 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115321902|UniProtKB=A0ACM8E249 A0ACM8E249 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120849924|UniProtKB=A0ACM8F7N1 A0ACM8F7N1 LOC120849924 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;system development#GO:0048731;neurogenesis#GO:0022008;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8041443|UniProtKB=A0ACM8DRK8 A0ACM8DRK8 LOC8041443 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121836538|UniProtKB=A0ACM8FZ09 A0ACM8FZ09 LOC121836538 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030489|UniProtKB=A0ACM8EMX7 A0ACM8EMX7 LOC8030489 PTHR18902:SF31 NUCLEAR MITOTIC APPARATUS PROTEIN 1-RELATED GOLGIN SUBFAMILY A MEMBER 3-LIKE cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8029710|UniProtKB=A0ACM8F9J0 A0ACM8F9J0 LOC8029710 PTHR12883:SF0 ADIPOCYTE-SPECIFIC PROTEIN 4-RELATED PAT COMPLEX SUBUNIT CCDC47 intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;macromolecule localization#GO:0033036;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization#GO:0016043 membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;protein folding chaperone complex#GO:0101031;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 IXOSC|EnsemblGenome=LOC8032973|UniProtKB=A0ACM8ELH4 A0ACM8ELH4 IntS8 PTHR13350:SF1 INTEGRATOR COMPLEX SUBUNIT 8 INTEGRATOR COMPLEX SUBUNIT 8 snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;integrator complex#GO:0032039;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8034130|UniProtKB=A0ACM8ECK9 A0ACM8ECK9 LOC8034130 PTHR12300:SF161 HVA22-LIKE PROTEINS RECEPTOR EXPRESSION-ENHANCING PROTEIN membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8036328|UniProtKB=A0ACM8G3T0 A0ACM8G3T0 LOC8036328 PTHR24264:SF91 TRYPSIN-RELATED PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120839007|UniProtKB=A0ACM8ELU7 A0ACM8ELU7 LOC120839007 PTHR16840:SF3 GROWTH ARREST-SPECIFIC PROTEIN 1 GROWTH ARREST-SPECIFIC PROTEIN 1 regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;biological regulation#GO:0065007;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of cellular process#GO:0050794 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115315334|UniProtKB=A0ACM8EUH2 A0ACM8EUH2 LOC115315334 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=ISCI003308|UniProtKB=B7PBI5 B7PBI5 ISCW003308 PTHR12592:SF0 ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE FAMILY MEMBER ATP-DEPENDENT (S)-NAD(P)H-HYDRATE DEHYDRATASE hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 IXOSC|EnsemblGenome=LOC115324250|UniProtKB=A0ACM8E4G9 A0ACM8E4G9 LOC115324250 PTHR46179:SF25 ZINC FINGER PROTEIN METAL RESPONSE ELEMENT-BINDING TRANSCRIPTION FACTOR-1, ISOFORM C regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120839491|UniProtKB=A0ACM8ELT8 A0ACM8ELT8 LOC120839491 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121046477|UniProtKB=A0ACM8FE45 A0ACM8FE45 LOC121046477 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8030866|UniProtKB=A0ACM8DN67 A0ACM8DN67 LOC8030866 PTHR13058:SF19 THREE PRIME REPAIR EXONUCLEASE 1, 2 LD40940P exonuclease activity#GO:0004527;hydrolase activity#GO:0016787;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;DNA catabolic process#GO:0006308;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8036751|UniProtKB=A0ACM8DSW1 A0ACM8DSW1 LOC8036751 PTHR11777:SF9 ALANYL-TRNA SYNTHETASE ALANINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;deacylase activity#GO:0160215;catalytic activity#GO:0003824;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8030623|UniProtKB=A0ACM8DS28 A0ACM8DS28 LOC8030623 PTHR14152:SF5 SQUAMOUS CELL CARCINOMA ANTIGEN RECOGNISED BY CYTOTOXIC T LYMPHOCYTES U4_U6.U5 TRI-SNRNP-ASSOCIATED PROTEIN 1 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;precatalytic spliceosome#GO:0071011;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8036887|UniProtKB=A0ACM8ED39 A0ACM8ED39 LOC8036887 PTHR10621:SF0 UV EXCISION REPAIR PROTEIN RAD23 UV EXCISION REPAIR PROTEIN RAD23 protein-containing complex binding#GO:0044877;protein binding#GO:0005515;ubiquitin binding#GO:0043130;polyubiquitin modification-dependent protein binding#GO:0031593;binding#GO:0005488;modification-dependent protein binding#GO:0140030 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 IXOSC|EnsemblGenome=LOC115318884|UniProtKB=A0ACM8EWS9 A0ACM8EWS9 LOC115318884 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8032072|UniProtKB=A0ACM8E559 A0ACM8E559 LOC8032072 PTHR24241:SF161 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089 cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to chemical#GO:0042221;biological regulation#GO:0065007;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115321560|UniProtKB=A0ACM8F2L9 A0ACM8F2L9 LOC115321560 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115322872|UniProtKB=A0ACM8E3F7 A0ACM8E3F7 LOC115322872 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120839099|UniProtKB=A0ACM8EMC7 A0ACM8EMC7 LOC120839099 PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488;U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;preribosome#GO:0030684 IXOSC|EnsemblGenome=LOC8028662|UniProtKB=A0ACM8DNC1 A0ACM8DNC1 Atac1 PTHR22705:SF0 ZINC FINGER, ZZ DOMAIN CONTAINING 3 ZZ-TYPE ZINC FINGER-CONTAINING PROTEIN 3 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115325067|UniProtKB=A0ACM8E5W2 A0ACM8E5W2 LOC115325067 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836684|UniProtKB=A0ACM8FZL4 A0ACM8FZL4 LOC121836684 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121832911|UniProtKB=A0ACM8FTR4 A0ACM8FTR4 LOC121832911 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847347|UniProtKB=A0ACM8F3Y8 A0ACM8F3Y8 LOC120847347 PTHR36943:SF2 CCHC-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040038|UniProtKB=A0ACM8FMY9 A0ACM8FMY9 PTHR24027:SF452 CADHERIN-23 NEURAL-CADHERIN 2-RELATED cell adhesion molecule binding#GO:0050839;binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609;cell migration#GO:0016477;cell motility#GO:0048870 extrinsic component of membrane#GO:0019898;extrinsic component of plasma membrane#GO:0019897;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069;cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 IXOSC|EnsemblGenome=LOC115314677|UniProtKB=A0ACM8EUV6 A0ACM8EUV6 LOC115314677 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8032007|UniProtKB=A0ACM8EAK0 A0ACM8EAK0 LOC8032007 PTHR10218:SF365 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA Q SUBUNIT-RELATED molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular response to nitrogen compound#GO:1901699;response to chemical#GO:0042221;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698 extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796 G-protein#PC00020;heterotrimeric G-protein#PC00117 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Endothelin signaling pathway#P00019>Gq#P00586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Wnt signaling pathway#P00057>Galpha#P01451;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057 IXOSC|EnsemblGenome=LOC115309984|UniProtKB=A0ACM8DPC4 A0ACM8DPC4 LOC115309984 PTHR14650:SF1 PROLYL HYDROXYLASE-RELATED 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 3 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120843099|UniProtKB=A0ACM8EV81 A0ACM8EV81 LOC120843099 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC115327547|UniProtKB=A0ACM8EW26 A0ACM8EW26 LOC115327547 PTHR11808:SF15 TRANS-SULFURATION ENZYME FAMILY MEMBER CYSTATHIONINE GAMMA-LYASE carbon-sulfur lyase activity#GO:0016846;lyase activity#GO:0016829;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;homocysteine metabolic process#GO:0050667;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 lyase#PC00144;metabolite interconversion enzyme#PC00262 Methionine biosynthesis#P02753>O-Succinyl homoserine lyase#P03026 IXOSC|EnsemblGenome=LOC115313992|UniProtKB=A0ACM8DTM4 A0ACM8DTM4 LOC115313992 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115321580|UniProtKB=A0ACM8F4D9 A0ACM8F4D9 LOC115321580 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC120847376|UniProtKB=A0ACM8FNE5 A0ACM8FNE5 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8037882|UniProtKB=A0ACM8F460 A0ACM8F460 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579 IXOSC|EnsemblGenome=LOC120850505|UniProtKB=A0ACM8FAA9 A0ACM8FAA9 LOC120850505 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115316102|UniProtKB=A0ACM8ES68 A0ACM8ES68 LOC115316102 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120841785|UniProtKB=A0ACM8FZS3 A0ACM8FZS3 RpL11 PTHR11994:SF8 60S RIBOSOMAL PROTEIN L11-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL5 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8024330|UniProtKB=A0ACM8DI63 A0ACM8DI63 LOC8024330 PTHR45617:SF165 LEUCINE RICH REPEAT FAMILY PROTEIN COMMON DPR-INTERACTING PROTEIN-RELATED scaffold/adaptor protein#PC00226 Toll receptor signaling pathway#P00054>TLR#P01346 IXOSC|EnsemblGenome=LOC121834999|UniProtKB=A0ACM8FRQ5 A0ACM8FRQ5 LOC121834999 PTHR45623:SF14 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094 cellular component organization#GO:0016043;cellular process#GO:0009987;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121834189|UniProtKB=A0ACM8FP56 A0ACM8FP56 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;reproductive process#GO:0022414;homologous recombination#GO:0035825;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8038343|UniProtKB=A0ACM8FQ09 A0ACM8FQ09 LOC8038343 PTHR23043:SF39 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA DYSFUSION, ISOFORM D DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121048099|UniProtKB=A0ACM8FHP0 A0ACM8FHP0 LOC121048099 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC121837931|UniProtKB=A0ACM8G6S4 A0ACM8G6S4 LOC121837931 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8041052|UniProtKB=A0ACM8DKL6 A0ACM8DKL6 LOC8041052 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8028507|UniProtKB=A0ACM8E126 A0ACM8E126 LOC8028507 PTHR11452:SF95 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 metabolic process#GO:0008152;oligosaccharide metabolic process#GO:0009311;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;glycosyl compound catabolic process#GO:1901658;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121;galactosidase#PC00104 IXOSC|EnsemblGenome=LOC115311724|UniProtKB=A0ACM8FU77 A0ACM8FU77 LOC115311724 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8024355|UniProtKB=A0ACM8EK73 A0ACM8EK73 LOC8024355 PTHR10404:SF84 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG catalytic activity#GO:0003824;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8039281|UniProtKB=A0ACM8FDK0 A0ACM8FDK0 Zasp52 PTHR24214:SF38 PDZ AND LIM DOMAIN PROTEIN ZASP PDZ AND LIM DOMAIN PROTEIN ZASP-RELATED protein binding#GO:0005515;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 cellular component organization or biogenesis#GO:0071840;anatomical structure development#GO:0048856;developmental process#GO:0032502;actin filament-based process#GO:0030029;animal gross anatomical part developmental process#GO:0160108;cytoskeleton organization#GO:0007010;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cell-cell junction#GO:0005911;actomyosin#GO:0042641;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;stress fiber#GO:0001725;actin filament#GO:0005884;cell junction#GO:0030054;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;adherens junction#GO:0005912;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC121047280|UniProtKB=A0ACM8FEL7 A0ACM8FEL7 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832853|UniProtKB=A0ACM8E3M4 A0ACM8E3M4 LOC121832853 PTHR12507:SF3 REDUCED GROWTH PHENOTYPE 1 RGP1, YEAST -RELATED RAB6A-GEF COMPLEX PARTNER PROTEIN 2 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;endomembrane system#GO:0012505;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;organelle membrane#GO:0031090;intracellular protein-containing complex#GO:0140535;bounding membrane of organelle#GO:0098588 IXOSC|EnsemblGenome=LOC8032440|UniProtKB=A0ACM8DJG7 A0ACM8DJG7 LOC8032440 PTHR21040:SF8 BCDNA.GH04120 HEXOSAMINIDASE D hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8040450|UniProtKB=A0ACM8G1F4 A0ACM8G1F4 LOC8040450 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120850327|UniProtKB=A0ACM8F8K0 A0ACM8F8K0 LOC120850327 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8025292|UniProtKB=A0ACM8E197 A0ACM8E197 LOC8025292 PTHR16001:SF4 ANGEL WING family ECTO-NOX DISULFIDE-THIOL EXCHANGER 1-RELATED oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120849077|UniProtKB=A0ACM8F649 A0ACM8F649 LOC120849077 PTHR45080:SF8 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE 1 ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987;cell junction organization#GO:0034330;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840 neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;membrane#GO:0016020;neuronal cell body#GO:0043025;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;axon#GO:0030424 IXOSC|EnsemblGenome=LOC8033554|UniProtKB=A0ACM8DTF7 A0ACM8DTF7 LOC8033554 PTHR13052:SF3 NFRKB-RELATED NUCLEAR FACTOR RELATED TO KAPPA-B-BINDING PROTEIN protein binding#GO:0005515;protease binding#GO:0002020;enzyme binding#GO:0019899;binding#GO:0005488 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115316892|UniProtKB=A0ACM8DWW8 A0ACM8DWW8 LOC115316892 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8024757|UniProtKB=A0ACM8E1P9 A0ACM8E1P9 LOC8024757 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838089|UniProtKB=A0ACM8G6D1 A0ACM8G6D1 LOC121838089 PTHR11675:SF143 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 3 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8053492|UniProtKB=A0ACM8G4B7 A0ACM8G4B7 LOC8053492 PTHR11473:SF46 AROMATIC AMINO ACID HYDROXYLASE PROTEIN HENNA oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497 proteinogenic amino acid biosynthetic process#GO:0170038;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;biogenic amine metabolic process#GO:0006576;amine metabolic process#GO:0009308;phenol-containing compound biosynthetic process#GO:0046189;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;catecholamine metabolic process#GO:0006584;serotonin metabolic process#GO:0042428;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;serotonin biosynthetic process#GO:0042427;small molecule catabolic process#GO:0044282;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;aromatic amino acid biosynthetic process#GO:0009073;indole-containing compound metabolic process#GO:0042430;carboxylic acid biosynthetic process#GO:0046394;phenol-containing compound metabolic process#GO:0018958 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120836400|UniProtKB=A0ACM8G8U3 A0ACM8G8U3 LOC120836400 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115308200|UniProtKB=A0ACM8E2H5 A0ACM8E2H5 LOC115308200 PTHR13222:SF5 RB1-INDUCIBLE COILED-COIL RB1-INDUCIBLE COILED-COIL PROTEIN 1 enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;protein binding#GO:0005515 catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;glycogen metabolic process#GO:0005977;vacuole organization#GO:0007033;energy reserve metabolic process#GO:0006112;organelle assembly#GO:0070925;macroautophagy#GO:0016236;reticulophagy#GO:0061709;glycogen catabolic process#GO:0005980;energy derivation by oxidation of organic compounds#GO:0015980;pexophagy#GO:0000425;macromolecule metabolic process#GO:0043170;autophagy of mitochondrion#GO:0000422;generation of precursor metabolites and energy#GO:0006091;polysaccharide metabolic process#GO:0005976;glucan catabolic process#GO:0009251;cellular component organization#GO:0016043;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;carbohydrate catabolic process#GO:0016052;process utilizing autophagic mechanism#GO:0061919;cellular component assembly#GO:0022607;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;phagophore assembly site#GO:0000407;catalytic complex#GO:1902494;transferase complex#GO:1990234;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8051766|UniProtKB=A0ACM8DXB7 A0ACM8DXB7 LOC8051766 PTHR12560:SF0 LONGEVITY ASSURANCE FACTOR 1 LAG1 LD18904P transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;ceramide metabolic process#GO:0006672 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8030504|UniProtKB=A0ACM8DS51 A0ACM8DS51 Sras PTHR13046:SF0 PROTEASE U48 CAAX PRENYL PROTEASE RCE1 CAAX PRENYL PROTEASE 2 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8028201|UniProtKB=A0ACM8DJL5 A0ACM8DJL5 Epg5 PTHR31139:SF4 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG ECTOPIC P GRANULES PROTEIN 5 HOMOLOG lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;lysosome#GO:0005764 IXOSC|EnsemblGenome=LOC8050641|UniProtKB=A0ACM8DUQ7 A0ACM8DUQ7 LOC8050641 PTHR24104:SF47 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED THIN, ISOFORM C catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8052798|UniProtKB=A0ACM8FVT3 A0ACM8FVT3 LOC8052798 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115324394|UniProtKB=A0ACM8E533 A0ACM8E533 LOC115324394 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838555|UniProtKB=A0ACM8G964 A0ACM8G964 LOC121838555 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 transferase#PC00220 IXOSC|EnsemblGenome=LOC115330949|UniProtKB=A0ACM8FFD6 A0ACM8FFD6 LOC115330949 PTHR10165:SF35 LIPID PHOSPHATE PHOSPHATASE RE23632P phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid dephosphorylation#GO:0046839;phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;dephosphorylation#GO:0016311;lipid modification#GO:0030258;metabolic process#GO:0008152;lipid metabolic process#GO:0006629 cellular anatomical structure#GO:0110165;membrane#GO:0016020 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120849002|UniProtKB=A0ACM8FH50 A0ACM8FH50 LOC120849002 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8038252|UniProtKB=A0ACM8E8J4 A0ACM8E8J4 LOC8038252 PTHR12358:SF112 SPHINGOSINE KINASE SPHINGOSINE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;sphingoid biosynthetic process#GO:0046520;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 kinase#PC00137;metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8041436|UniProtKB=A0ACM8ELS8 A0ACM8ELS8 Delta PTHR24044:SF488 NOTCH LIGAND FAMILY MEMBER DELTA-LIKE PROTEIN binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 negative regulation of cellular process#GO:0048523;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;negative regulation of Notch signaling pathway#GO:0045746;Notch signaling pathway#GO:0007219;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signaling#GO:0023057;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8042708|UniProtKB=A0ACM8E2C8 A0ACM8E2C8 LOC8042708 PTHR11730:SF58 AMMONIUM TRANSPORTER AMMONIUM TRANSPORTER transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 homeostatic process#GO:0042592;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC120845940|UniProtKB=A0ACM8F0E4 A0ACM8F0E4 LOC120845940 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC121832964|UniProtKB=A0ACM8FQN0 A0ACM8FQN0 PTHR22426:SF2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 IXOSC|EnsemblGenome=LOC115329929|UniProtKB=A0ACM8G043 A0ACM8G043 LOC115329929 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121837623|UniProtKB=A0ACM8G3Z2 A0ACM8G3Z2 LOC121837623 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115313199|UniProtKB=A0ACM8F8B5 A0ACM8F8B5 LOC115313199 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8028815|UniProtKB=A0ACM8EV01 A0ACM8EV01 LOC8028815 PTHR23345:SF38 VITELLOGENIN-RELATED APOLIPOPROTEIN LIPID TRANSFER PARTICLE lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 storage protein#PC00210 IXOSC|EnsemblGenome=LOC8024769|UniProtKB=A0ACM8E9U5 A0ACM8E9U5 LOC8024769 PTHR11749:SF3 RIBULOSE-5-PHOSPHATE-3-EPIMERASE RIBULOSE-PHOSPHATE 3-EPIMERASE isomerase activity#GO:0016853;racemase and epimerase activity#GO:0016854;catalytic activity#GO:0003824;racemase and epimerase activity, acting on carbohydrates and derivatives#GO:0016857;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;D-ribulose-phosphate 3-epimerase activity#GO:0004750 nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;carbohydrate derivative metabolic process#GO:1901135;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;glyceraldehyde-3-phosphate metabolic process#GO:0019682;NADPH regeneration#GO:0006740;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;pentose-phosphate shunt, non-oxidative branch#GO:0009052;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Ascorbate degradation#P02729>L-xylulose-5-phosphate-3-epimerase#P02852 IXOSC|EnsemblGenome=LOC121837484|UniProtKB=A0ACM8G3A8 A0ACM8G3A8 LOC121837484 PTHR47526:SF4 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8031585|UniProtKB=A0ACM8E4F5 A0ACM8E4F5 LOC8031585 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;organelle membrane contact site#GO:0044232 IXOSC|EnsemblGenome=LOC8050408|UniProtKB=A0ACM8EEU1 A0ACM8EEU1 PTHR22780:SF5 ADAPTIN, ALPHA/GAMMA/EPSILON AP-1 COMPLEX SUBUNIT GAMMA cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;Golgi to endosome transport#GO:0006895;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641 intracellular vesicle#GO:0097708;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;organelle#GO:0043226;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular organelle#GO:0043229;coated membrane#GO:0048475;coated vesicle#GO:0030135;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;vesicle coat#GO:0030120;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;membrane coat#GO:0030117;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;transport vesicle#GO:0030133;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi-associated vesicle#GO:0005798;organelle membrane#GO:0031090 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115315610|UniProtKB=A0ACM8EKF0 A0ACM8EKF0 LOC115315610 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8044135|UniProtKB=A0ACM8E860 A0ACM8E860 LOC8044135 PTHR11588:SF501 TUBULIN TUBULIN ALPHA CHAIN carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 tubulin#PC00228;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8037571|UniProtKB=A0ACM8DK38 A0ACM8DK38 eIF3j PTHR21681:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT J translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of translational initiation#GO:0006446;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 eukaryotic translation initiation factor 3 complex#GO:0005852;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC120838411|UniProtKB=A0ACM8EJ74 A0ACM8EJ74 LOC120838411 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115325023|UniProtKB=A0ACM8F081 A0ACM8F081 LOC115325023 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8051983|UniProtKB=A0ACM8E4C8 A0ACM8E4C8 LOC8051983 PTHR11680:SF28 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, MITOCHONDRIAL transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;carboxylic acid biosynthetic process#GO:0046394;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 IXOSC|EnsemblGenome=LOC115325816|UniProtKB=A0ACM8E643 A0ACM8E643 LOC115325816 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850673|UniProtKB=A0ACM8FBF9 A0ACM8FBF9 LOC120850673 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8041779|UniProtKB=A0ACM8E9Z6 A0ACM8E9Z6 LOC8041779 PTHR19845:SF0 KATANIN P80 SUBUNIT KATANIN P80 WD40 REPEAT-CONTAINING SUBUNIT B1 protein-containing complex disassembly#GO:0032984;cytoskeleton organization#GO:0007010;protein depolymerization#GO:0051261;microtubule depolymerization#GO:0007019;cellular process#GO:0009987;microtubule polymerization or depolymerization#GO:0031109;organelle organization#GO:0006996;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cellular component disassembly#GO:0022411 microtubule cytoskeleton#GO:0015630;organelle#GO:0043226;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121836619|UniProtKB=A0ACM8FYX1 A0ACM8FYX1 LOC121836619 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8053328|UniProtKB=A0ACM8DL82 A0ACM8DL82 LOC8053328 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 IXOSC|EnsemblGenome=LOC121046846|UniProtKB=A0ACM8FDR2 A0ACM8FDR2 LOC121046846 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120835943|UniProtKB=A0ACM8F2S2 A0ACM8F2S2 LOC120835943 PTHR11208:SF45 RNA-BINDING PROTEIN RELATED SPLICING FACTOR 1 RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA cis splicing, via spliceosome#GO:0045292;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8051112|UniProtKB=A0ACM8DLD4 A0ACM8DLD4 LOC8051112 PTHR23504:SF1 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 10 GH21943P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC115319455|UniProtKB=A0ACM8ELA2 A0ACM8ELA2 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120839711|UniProtKB=A0ACM8FZA2 A0ACM8FZA2 LOC120839711 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8023528|UniProtKB=A0ACM8EEY8 A0ACM8EEY8 LOC8023528 PTHR13318:SF265 PARTNER OF PAIRED, ISOFORM B-RELATED F-BOX DOMAIN-CONTAINING PROTEIN catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 IXOSC|EnsemblGenome=LOC8030712|UniProtKB=A0ACM8DHF1 A0ACM8DHF1 LOC8030712 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8027059|UniProtKB=A0ACM8DZU4 A0ACM8DZU4 Sulf1 PTHR43108:SF16 N-ACETYLGLUCOSAMINE-6-SULFATASE FAMILY MEMBER EXTRACELLULAR SULFATASE SULF-1 HOMOLOG catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;positive regulation of cell communication#GO:0010647;positive regulation of cytokine production#GO:0001819;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;carbohydrate derivative catabolic process#GO:1901136;protein metabolic process#GO:0019538;positive regulation of biosynthetic process#GO:0009891;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of cytokine production#GO:0001817;carbohydrate derivative metabolic process#GO:1901135;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;negative regulation of biological process#GO:0048519;positive regulation of multicellular organismal process#GO:0051240;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of signal transduction#GO:0009968;regulation of multicellular organismal process#GO:0051239;regulation of fibroblast growth factor receptor signaling pathway#GO:0040036;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan metabolic process#GO:0006029 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;cell surface#GO:0009986 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8033194|UniProtKB=A0ACM8DHJ8 A0ACM8DHJ8 LOC8033194 PTHR34929:SF1 ZGC:153157 INAF MOTIF CONTAINING 2 IXOSC|EnsemblGenome=LOC8024758|UniProtKB=A0ACM8E2D1 A0ACM8E2D1 LOC8024758 PTHR13451:SF0 CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81 STRUCTURE-SPECIFIC ENDONUCLEASE SUBUNIT MUS81 DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 DNA damage checkpoint signaling#GO:0000077;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;double-strand break repair via break-induced replication#GO:0000727;DNA integrity checkpoint signaling#GO:0031570;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;resolution of meiotic recombination intermediates#GO:0000712;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;homologous recombination#GO:0035825;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;reciprocal homologous recombination#GO:0140527;organelle fission#GO:0048285;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;signal transduction#GO:0007165;cellular component organization or biogenesis#GO:0071840;negative regulation of cell cycle#GO:0045786;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;cellular component organization#GO:0016043;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;negative regulation of biological process#GO:0048519;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;negative regulation of mitotic cell cycle#GO:0045930;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endonuclease complex#GO:1905348 IXOSC|EnsemblGenome=LOC8026177|UniProtKB=A0ACM8FYJ7 A0ACM8FYJ7 LOC8026177 PTHR14320:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 COILED-COIL DOMAIN-CONTAINING PROTEIN 181 IXOSC|EnsemblGenome=LOC8036384|UniProtKB=A0ACM8EF41 A0ACM8EF41 LOC8036384 PTHR16024:SF28 XK-RELATED PROTEIN XK-RELATED PROTEIN anatomical structure development#GO:0048856;localization#GO:0051179;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cell death#GO:0008219;programmed cell death#GO:0012501;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;transport#GO:0006810;developmental process#GO:0032502;phagocytosis#GO:0006909;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007;phospholipid translocation#GO:0045332;lipid transport#GO:0006869;macromolecule localization#GO:0033036;regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;lipid localization#GO:0010876;endocytosis#GO:0006897;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;cellular component organization#GO:0016043;import into cell#GO:0098657;apoptotic cell clearance#GO:0043277;cellular component organization or biogenesis#GO:0071840;phagocytosis, engulfment#GO:0006911;membrane invagination#GO:0010324;endomembrane system organization#GO:0010256;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120837155|UniProtKB=A0ACM8EHE8 A0ACM8EHE8 LOC120837155 PTHR15633:SF2 NUCLEOLAR PROTEIN 11 NUCLEOLAR PROTEIN 11 ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC121836427|UniProtKB=A0ACM8FZX3 A0ACM8FZX3 LOC121836427 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310426|UniProtKB=A0ACM8DPQ4 A0ACM8DPQ4 LOC115310426 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115309934|UniProtKB=A0ACM8F5S5 A0ACM8F5S5 LOC115309934 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC8025590|UniProtKB=A0ACM8DTQ7 A0ACM8DTQ7 LOC8025590 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8033747|UniProtKB=A0ACM8DIA4 A0ACM8DIA4 LOC8033747 PTHR13271:SF163 UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE ACTIN-HISTIDINE N-METHYLTRANSFERASE lysine N-methyltransferase activity#GO:0016278;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC115325242|UniProtKB=A0ACM8E5G4 A0ACM8E5G4 LOC115325242 PTHR15627:SF8 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 TRNA-URIDINE AMINOCARBOXYPROPYLTRANSFERASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8050438|UniProtKB=A0ACM8FC55 A0ACM8FC55 LOC8050438 PTHR10772:SF67 10 KDA HEAT SHOCK PROTEIN 10 KDA HEAT SHOCK PROTEIN, MITOCHONDRIAL cation binding#GO:0043169;protein binding#GO:0005515;metal ion binding#GO:0046872;ion binding#GO:0043167;protein-folding chaperone binding#GO:0051087;small molecule binding#GO:0036094;binding#GO:0005488 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 chaperonin#PC00073 IXOSC|EnsemblGenome=LOC121046550|UniProtKB=A0ACM8FEF1 A0ACM8FEF1 LOC121046550 PTHR33064:SF47 POL PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036867|UniProtKB=A0ACM8EUM9 A0ACM8EUM9 LOC8036867 PTHR46344:SF27 OS02G0202900 PROTEIN KELCH REPEAT SUPERFAMILY PROTEIN IXOSC|EnsemblGenome=LOC115312966|UniProtKB=A0ACM8FNG6 A0ACM8FNG6 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837944|UniProtKB=A0ACM8G6R0 A0ACM8G6R0 LOC120837944 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8024128|UniProtKB=A0ACM8G7M9 A0ACM8G7M9 LOC8024128 PTHR23138:SF190 RAN BINDING PROTEIN E3 SUMO-PROTEIN LIGASE RANBP2 aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;NLS-bearing protein import into nucleus#GO:0006607;nuclear export#GO:0051168;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913 membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle envelope#GO:0031967 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8035882|UniProtKB=A0ACM8E6H5 A0ACM8E6H5 LOC8035882 PTHR47533:SF4 PROTEIN CBG21859 AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047454|UniProtKB=A0ACM8G3Q3 A0ACM8G3Q3 LOC121047454 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8026741|UniProtKB=A0ACM8G7Q2 A0ACM8G7Q2 LOC8026741 PTHR22916:SF73 GLYCOSYLTRANSFERASE QUEUOSINE-TRNA GALACTOSYLTRANSFERASE galactosyltransferase activity#GO:0008378;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194;hexosyltransferase activity#GO:0016758;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740 tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8032860|UniProtKB=A0ACM8E624 A0ACM8E624 ric8a PTHR12425:SF5 SYNEMBRYN CHAPERONE RIC-8 nucleoside-triphosphatase regulator activity#GO:0060589;protein binding#GO:0005515;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120847578|UniProtKB=A0ACM8F4B2 A0ACM8F4B2 LOC120847578 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850300|UniProtKB=A0ACM8F8G7 A0ACM8F8G7 LOC120850300 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8042424|UniProtKB=A0ACM8DQM4 A0ACM8DQM4 LOC8042424 PTHR23063:SF63 PHOSPHOLIPID ACYLTRANSFERASE LYSOPHOSPHATIDYLCHOLINE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115321705|UniProtKB=A0ACM8FKP9 A0ACM8FKP9 LOC115321705 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC8025593|UniProtKB=A0ACM8DJD0 A0ACM8DJD0 LOC8025593 PTHR14224:SF37 SIMILAR TO PREFERENTIALLY EXPRESSED ANTIGEN IN MELANOMA-LIKE 3 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 14 IXOSC|EnsemblGenome=LOC8039840|UniProtKB=A0ACM8FVC1 A0ACM8FVC1 LOC8039840 PTHR18952:SF283 CARBONIC ANHYDRASE CARBONIC ANHYDRASE XB-RELATED dehydratase#PC00091;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835364|UniProtKB=A0ACM8FUA1 A0ACM8FUA1 LOC121835364 PTHR46358:SF1 TONSOKU-LIKE PROTEIN TONSOKU-LIKE PROTEIN nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;response to stress#GO:0006950;cellular process#GO:0009987;replication fork processing#GO:0031297;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8031520|UniProtKB=A0ACM8FTA0 A0ACM8FTA0 LOC8031520 PTHR16317:SF2 INTEGRIN ALPHA REPEAT DOMAIN-CONTAINING INTEGRIN ALPHA FG-GAP REPEAT CONTAINING 2 integrin#PC00126 IXOSC|EnsemblGenome=LOC8031765|UniProtKB=A0ACM8DUX8 A0ACM8DUX8 LOC8031765 PTHR45843:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 4 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8035753|UniProtKB=A0ACM8DZF1 A0ACM8DZF1 LOC8035753 PTHR11214:SF378 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 4 transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120838345|UniProtKB=A0ACM8EKB8 A0ACM8EKB8 LOC120838345 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8034967|UniProtKB=A0ACM8FXZ3 A0ACM8FXZ3 LOC8034967 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115311169|UniProtKB=A0ACM8EVU9 A0ACM8EVU9 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121837065|UniProtKB=A0ACM8G2Y2 A0ACM8G2Y2 LOC121837065 PTHR46481:SF16 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 BED-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836375|UniProtKB=A0ACM8EET6 A0ACM8EET6 LOC120836375 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8024748|UniProtKB=A0ACM8EAM5 A0ACM8EAM5 LOC8024748 PTHR10037:SF293 VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 sodium channel activity#GO:0005272;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;sodium ion transmembrane transporter activity#GO:0015081;monoatomic cation channel activity#GO:0005261;channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated sodium channel activity#GO:0005248;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832 transport#GO:0006810;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;regulation of biological quality#GO:0065008;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;calcium ion import#GO:0070509;action potential#GO:0001508;biological regulation#GO:0065007;membrane depolarization#GO:0051899;metal ion transport#GO:0030001 membrane protein complex#GO:0098796;membrane#GO:0016020;neuron projection#GO:0043005;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;sodium channel complex#GO:0034706 voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC115321617|UniProtKB=A0ACM8EVN9 A0ACM8EVN9 LOC115321617 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041162|UniProtKB=A0ACM8DKM6 A0ACM8DKM6 LOC8041162 PTHR13293:SF6 AKIRIN-RELATED AKIRIN-RELATED transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 positive regulation of macromolecule metabolic process#GO:0010604;regulation of response to external stimulus#GO:0032101;positive regulation of immune system process#GO:0002684;positive regulation of biological process#GO:0048518;positive regulation of response to external stimulus#GO:0032103;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of response to stimulus#GO:0048584;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of innate immune response#GO:0045089;regulation of innate immune response#GO:0045088;regulation of biosynthetic process#GO:0009889;positive regulation of response to biotic stimulus#GO:0002833;regulation of gene expression#GO:0010468;regulation of response to stress#GO:0080134;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stimulus#GO:0048583;regulation of macromolecule metabolic process#GO:0060255;regulation of immune system process#GO:0002682;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of response to biotic stimulus#GO:0002831;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of immune response#GO:0050776;regulation of defense response#GO:0031347 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC115326730|UniProtKB=A0ACM8E6C2 A0ACM8E6C2 LOC115326730 PTHR21236:SF7 GOLGI MEMBRANE PROTEIN YIP1 PROTEIN YIPF4 intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;vesicle organization#GO:0016050;organelle organization#GO:0006996;membrane fusion#GO:0061025;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle fusion#GO:0048284;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular component organization#GO:0016043;Golgi organization#GO:0007030;vesicle fusion#GO:0006906 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 structural protein#PC00211 IXOSC|EnsemblGenome=LOC120850255|UniProtKB=A0ACM8F9L3 A0ACM8F9L3 LOC120850255 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838824|UniProtKB=A0ACM8G1X9 A0ACM8G1X9 LOC120838824 PTHR24027:SF422 CADHERIN-23 CADHERIN protein binding#GO:0005515;beta-catenin binding#GO:0008013;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;cellular component assembly#GO:0022607;cell migration#GO:0016477;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;cell-cell junction assembly#GO:0007043;cellular component organization or biogenesis#GO:0071840;anatomical structure morphogenesis#GO:0009653;cell junction assembly#GO:0034329;adherens junction organization#GO:0034332;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cell motility#GO:0048870;cell morphogenesis#GO:0000902;cell adhesion#GO:0007155;anatomical structure development#GO:0048856 anchoring junction#GO:0070161;adherens junction#GO:0005912;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cell junction#GO:0030054;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;cell-cell junction#GO:0005911;membrane#GO:0016020;membrane protein complex#GO:0098796 cadherin#PC00057;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8052237|UniProtKB=A0ACM8DM16 A0ACM8DM16 LOC8052237 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121836870|UniProtKB=A0ACM8G116 A0ACM8G116 LOC121836870 PTHR16515:SF21 PR DOMAIN ZINC FINGER PROTEIN PR DOMAIN ZINC FINGER PROTEIN 13 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8051791|UniProtKB=A0ACM8DLP0 A0ACM8DLP0 LOC8051791 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8038235|UniProtKB=A0ACM8DY24 A0ACM8DY24 elgi PTHR15315:SF26 RING FINGER PROTEIN 41, 151 E3 UBIQUITIN-PROTEIN LIGASE NRDP1 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 IXOSC|EnsemblGenome=ISCI009002|UniProtKB=B7PY76 B7PY76 ISCW009002 PTHR19855:SF11 WD40 REPEAT PROTEIN 12, 37 RIBOSOME BIOGENESIS PROTEIN WDR12 HOMOLOG IXOSC|EnsemblGenome=LOC8030054|UniProtKB=A0ACM8DJ71 A0ACM8DJ71 LOC8030054 PTHR12101:SF1 POPEYE DOMAIN CONTAINING PROTEIN BVES nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleotide binding#GO:0000166;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ribonucleotide binding#GO:0032553 multicellular organismal process#GO:0032501;heart development#GO:0007507;biological regulation#GO:0065007;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cellular developmental process#GO:0048869;animal organ development#GO:0048513;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;striated muscle cell differentiation#GO:0051146;developmental process#GO:0032502;muscle structure development#GO:0061061;cell differentiation#GO:0030154;circulatory system development#GO:0072359;muscle cell differentiation#GO:0042692;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155 anchoring junction#GO:0070161;cell junction#GO:0030054;sarcolemma#GO:0042383;tight junction#GO:0070160;apical junction complex#GO:0043296;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 IXOSC|EnsemblGenome=LOC8039418|UniProtKB=A0ACM8G2U3 A0ACM8G2U3 LOC8039418 PTHR22589:SF14 CARNITINE O-ACYLTRANSFERASE CHOLINE O-ACETYLTRANSFERASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cellular process#GO:0009987;regulation of biological process#GO:0050789;anterograde trans-synaptic signaling#GO:0098916;signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;biosynthetic process#GO:0009058;neuromuscular synaptic transmission#GO:0007274;trans-synaptic signaling#GO:0099537;metabolic process#GO:0008152;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC115329054|UniProtKB=A0ACM8G4N7 A0ACM8G4N7 LOC115329054 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8038623|UniProtKB=A0ACM8FWL6 A0ACM8FWL6 LOC8038623 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8053067|UniProtKB=A0ACM8FPQ2 A0ACM8FPQ2 PTHR16228:SF7 DIVALENT CATION TRANSPORTER SOLUTE CARRIER FAMILY 41 SLC41A_MGTE INTEGRAL MEMBRANE DOMAIN-CONTAINING PROTEIN plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8039121|UniProtKB=A0ACM8E1G8 A0ACM8E1G8 LOC8039121 PTHR14773:SF0 WD REPEAT-CONTAINING PROTEIN 76 WD REPEAT-CONTAINING PROTEIN 76 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of cell cycle phase transition#GO:1901987;regulation of cell cycle#GO:0051726;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of response to stress#GO:0080134;regulation of intracellular signal transduction#GO:1902531;regulation of cellular response to stress#GO:0080135 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;heterochromatin#GO:0000792;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8043273|UniProtKB=A0ACM8DYN5 A0ACM8DYN5 LOC8043273 PTHR13303:SF0 PREFOLDIN SUBUNIT 2 PREFOLDIN SUBUNIT 2 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 protein-containing complex#GO:0032991 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115310266|UniProtKB=A0ACM8G576 A0ACM8G576 LOC115310266 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836893|UniProtKB=A0ACM8EGP3 A0ACM8EGP3 LOC120836893 PTHR23098:SF16 AGAP001331-PA-RELATED GT1 DOMAIN-CONTAINING PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115309345|UniProtKB=A0ACM8DNM3 A0ACM8DNM3 LOC115309345 PTHR47217:SF1 GLOBIN-LIKE PROTEIN GLOBIN-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8042173|UniProtKB=A0ACM8DZL9 A0ACM8DZL9 LOC8042173 PTHR10328:SF3 PROTEIN MAX MYC-ASSOCIATED FACTOR X PROTEIN MAX transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 basic helix-loop-helix transcription factor#PC00055;DNA-binding transcription factor#PC00218 Oxidative stress response#P00046>Max#P01133 IXOSC|EnsemblGenome=LOC115310273|UniProtKB=A0ACM8DPK8 A0ACM8DPK8 LOC115310273 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115331897|UniProtKB=A0ACM8EDL6 A0ACM8EDL6 LOC115331897 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8036499|UniProtKB=A0ACM8DUQ9 A0ACM8DUQ9 ttv PTHR48261:SF3 ACETYLGLUCOSAMINYLTRANSFERASE N-ACETYLGLUCOSAMINYL-PROTEOGLYCAN 4-BETA-GLUCURONOSYLTRANSFERASE IXOSC|EnsemblGenome=LOC120843100|UniProtKB=A0ACM8EVB7 A0ACM8EVB7 LOC120843100 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035342|UniProtKB=A0ACM8DME0 A0ACM8DME0 LOC8035342 PTHR19211:SF15 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 2 ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;ATP binding#GO:0005524;small molecule binding#GO:0036094 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC8036207|UniProtKB=A0ACM8FXG6 A0ACM8FXG6 SmD3 PTHR23338:SF17 SMALL NUCLEAR RIBONUCLEOPROTEIN SM SMALL NUCLEAR RIBONUCLEOPROTEIN SM D3 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;spliceosomal snRNP assembly#GO:0000387;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;cellular component assembly#GO:0022607;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;cytoplasm#GO:0005737;U1 snRNP#GO:0005685;protein-containing complex#GO:0032991;U2 snRNP#GO:0005686;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U4 snRNP#GO:0005687;U2-type spliceosomal complex#GO:0005684;cellular anatomical structure#GO:0110165;organelle#GO:0043226;spliceosomal tri-snRNP complex#GO:0097526;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;SMN-Sm protein complex#GO:0034719;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525 RNA processing factor#PC00147;RNA splicing factor#PC00148;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120843922|UniProtKB=A0ACM8FEY9 A0ACM8FEY9 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115315186|UniProtKB=A0ACM8F029 A0ACM8F029 LOC115315186 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC115325788|UniProtKB=A0ACM8E6I1 A0ACM8E6I1 LOC115325788 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115330502|UniProtKB=A0ACM8FB72 A0ACM8FB72 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8037828|UniProtKB=A0ACM8F704 A0ACM8F704 LOC8037828 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8050492|UniProtKB=A0ACM8FFZ6 A0ACM8FFZ6 Reck PTHR13487:SF4 SERINE PROTEASE INHIBITOR FI21605P1 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678 regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular component organization#GO:0016043;regulation of canonical Wnt signaling pathway#GO:0060828;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;extracellular matrix organization#GO:0030198;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;extracellular structure organization#GO:0043062 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115331738|UniProtKB=A0ACM8ECX7 A0ACM8ECX7 LOC115331738 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846925|UniProtKB=A0ACM8FLE6 A0ACM8FLE6 LOC120846925 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120846289|UniProtKB=A0ACM8F1Y6 A0ACM8F1Y6 LOC120846289 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8036002|UniProtKB=A0ACM8FXR4 A0ACM8FXR4 LOC8036002 PTHR31804:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15 intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847 IXOSC|EnsemblGenome=LOC8026496|UniProtKB=A0ACM8EH83 A0ACM8EH83 LOC8026496 PTHR11475:SF147 OXIDASE/PEROXIDASE PEROXIDASIN peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037176|UniProtKB=A0ACM8E5J2 A0ACM8E5J2 LOC8037176 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052510|UniProtKB=A0ACM8DP75 A0ACM8DP75 LOC8052510 PTHR34093:SF1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 CHLORIDE CHANNEL CLIC-LIKE PROTEIN 1 channel activity#GO:0015267;monoatomic anion channel activity#GO:0005253;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;calcium ion homeostasis#GO:0055074;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8041614|UniProtKB=A0ACM8E652 A0ACM8E652 LOC8041614 PTHR45862:SF1 PROTEIN SGT1 HOMOLOG PROTEIN SGT1 HOMOLOG IXOSC|EnsemblGenome=LOC120839035|UniProtKB=A0ACM8EL48 A0ACM8EL48 LOC120839035 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115320776|UniProtKB=A0ACM8E1J4 A0ACM8E1J4 LOC115320776 PTHR12888:SF0 PEROXISOME ASSEMBLY PROTEIN 12 PEROXIN-12 PEROXISOME ASSEMBLY PROTEIN 12 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;peroxisome organization#GO:0007031 peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115324168|UniProtKB=A0ACM8F0E8 A0ACM8F0E8 LOC115324168 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115323228|UniProtKB=A0ACM8E2U2 A0ACM8E2U2 LOC115323228 PTHR31733:SF1 RIBONUCLEASE KAPPA RIBONUCLEASE KAPPA localization#GO:0051179;monoatomic cation transport#GO:0006812;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 transporter complex#GO:1990351;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;proton-transporting two-sector ATPase complex#GO:0016469;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533 endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC120836473|UniProtKB=A0ACM8EG28 A0ACM8EG28 LOC120836473 PTHR10174:SF208 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED CRAL-TRIO DOMAIN-CONTAINING PROTEIN DDB_G0278031 phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8023771|UniProtKB=A0ACM8DPR6 A0ACM8DPR6 RpS17 PTHR10732:SF0 40S RIBOSOMAL PROTEIN S17 SMALL RIBOSOMAL SUBUNIT PROTEIN ES17 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8036802|UniProtKB=A0ACM8DV38 A0ACM8DV38 CCT5 PTHR11353:SF94 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT EPSILON metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;protein folding#GO:0006457;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829;chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 IXOSC|EnsemblGenome=LOC8027815|UniProtKB=A0ACM8DVV3 A0ACM8DVV3 LOC8027815 PTHR47679:SF3 PROTEIN TORNADO 1 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121833218|UniProtKB=A0ACM8FKV4 A0ACM8FKV4 LOC121833218 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033146|UniProtKB=A0ACM8EAK5 A0ACM8EAK5 LOC8033146 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115316116|UniProtKB=A0ACM8EU53 A0ACM8EU53 LOC115316116 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847592|UniProtKB=A0ACM8FLK5 A0ACM8FLK5 LOC120847593 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8043849|UniProtKB=A0ACM8E0X2 A0ACM8E0X2 LOC8043849 PTHR44027:SF8 DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG DNAJ HOMOLOG SUBFAMILY C MEMBER 5 HOMOLOG regulation of trans-synaptic signaling#GO:0099177;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of signaling#GO:0023051 axon terminus#GO:0043679;cell junction#GO:0030054;axon#GO:0030424;neuron projection terminus#GO:0044306;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;terminal bouton#GO:0043195;distal axon#GO:0150034;synapse#GO:0045202;cellular anatomical structure#GO:0110165;presynapse#GO:0098793;neuron projection#GO:0043005 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115332811|UniProtKB=A0ACM8EEN5 A0ACM8EEN5 LOC115332811 PTHR13234:SF82 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE-LIKE PROTEIN catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115331836|UniProtKB=A0ACM8EDX1 A0ACM8EDX1 LOC115331836 PTHR11165:SF24 SKP1 S-PHASE KINASE-ASSOCIATED PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488 catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115329107|UniProtKB=A0ACM8F2Y3 A0ACM8F2Y3 LOC115329107 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028699|UniProtKB=A0ACM8G280 A0ACM8G280 LOC8028699 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC120850364|UniProtKB=A0ACM8FAP7 A0ACM8FAP7 LOC120850364 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115314446|UniProtKB=A0ACM8FLB2 A0ACM8FLB2 LOC115314446 PTHR11662:SF462 SOLUTE CARRIER FAMILY 17 FI19708P1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115333126|UniProtKB=A0ACM8F0S7 A0ACM8F0S7 LOC115333126 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8025463|UniProtKB=A0ACM8FCK4 A0ACM8FCK4 LOC8025463 PTHR23359:SF70 NUCLEOTIDE KINASE ADENYLATE KINASE ISOENZYME 1 phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleobase-containing compound kinase activity#GO:0019205;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 IXOSC|EnsemblGenome=LOC115330653|UniProtKB=A0ACM8EBH4 A0ACM8EBH4 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8029830|UniProtKB=A0ACM8EBN9 A0ACM8EBN9 LOC8029830 PTHR46621:SF1 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 SNRNA-ACTIVATING PROTEIN COMPLEX SUBUNIT 4 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 snRNA metabolic process#GO:0016073;snRNA transcription by RNA polymerase III#GO:0042796;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;snRNA transcription#GO:0009301;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC120848682|UniProtKB=A0ACM8FL35 A0ACM8FL35 LOC120848682 PTHR10509:SF14 O-METHYLTRANSFERASE-RELATED CATECHOL O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115329648|UniProtKB=A0ACM8E9X7 A0ACM8E9X7 LOC115329648 PTHR47526:SF6 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120844155|UniProtKB=A0ACM8G712 A0ACM8G712 LOC120844155 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED serine-type peptidase activity#GO:0008236;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120841229|UniProtKB=A0ACM8ERD7 A0ACM8ERD7 LOC120841229 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8027974|UniProtKB=A0ACM8G2I9 A0ACM8G2I9 LOC8027974 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115314287|UniProtKB=A0ACM8DU03 A0ACM8DU03 LOC115314287 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8050864|UniProtKB=A0ACM8DLL5 A0ACM8DLL5 LOC8050864 PTHR12052:SF5 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4A RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397 Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991;U4/U6 x U5 tri-snRNP complex#GO:0046540;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8029839|UniProtKB=A0ACM8DMX8 A0ACM8DMX8 LOC8029839 PTHR12693:SF3 MENIN MENIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;regulation of gene expression#GO:0010468;positive regulation of gene expression#GO:0010628;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;biosynthetic process#GO:0009058;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 CCKR signaling map#P06959>MEN1#P07084 IXOSC|EnsemblGenome=LOC8030131|UniProtKB=A0ACM8EKV9 A0ACM8EKV9 LOC8030131 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081 organophosphate catabolic process#GO:0046434;ceramide metabolic process#GO:0006672;phosphorus metabolic process#GO:0006793;sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;lipid catabolic process#GO:0016042;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;sphingomyelin metabolic process#GO:0006684;lipid biosynthetic process#GO:0008610 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;lysosome#GO:0005764;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121835101|UniProtKB=A0ACM8FRG8 A0ACM8FRG8 LOC121835101 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8041475|UniProtKB=A0ACM8G5S8 A0ACM8G5S8 LOC8041475 PTHR44086:SF14 THIOSULFATE SULFURTRANSFERASE RDL2, MITOCHONDRIAL-RELATED RHODANESE DOMAIN-CONTAINING PROTEIN sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 transferase#PC00220 IXOSC|EnsemblGenome=LOC121836183|UniProtKB=A0ACM8FXT1 A0ACM8FXT1 LOC121836183 PTHR11727:SF30 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transcription regulator activity#GO:0140110;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a rRNA#GO:0140102;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 mitochondrial RNA metabolic process#GO:0000959;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;mitochondrial gene expression#GO:0140053;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;mitochondrial transcription#GO:0006390;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;methylation#GO:0032259;RNA metabolic process#GO:0016070;rRNA modification#GO:0000154;DNA-templated transcription initiation#GO:0006352;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115312145|UniProtKB=A0ACM8EPG9 A0ACM8EPG9 LOC115312145 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120847965|UniProtKB=A0ACM8FPT6 A0ACM8FPT6 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318771|UniProtKB=A0ACM8FTL8 A0ACM8FTL8 LOC115318771 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=LOC121047135|UniProtKB=A0ACM8FFL3 A0ACM8FFL3 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8029609|UniProtKB=A0ACM8EPM4 A0ACM8EPM4 LOC8029609 PTHR22115:SF4 C3ORF6 PROTEIN-RELATED COILED-COIL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843996|UniProtKB=A0ACM8FPF8 A0ACM8FPF8 PTHR23339:SF109 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE TYR_PHOSPHATASE_2 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC115331867|UniProtKB=A0ACM8EKN8 A0ACM8EKN8 LOC115331867 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8029069|UniProtKB=A0ACM8DHJ3 A0ACM8DHJ3 LOC8029069 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8031716|UniProtKB=A0ACM8EXW6 A0ACM8EXW6 LOC8031716 PTHR24289:SF24 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 21-HYDROXYLASE oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;regulation of biological quality#GO:0065008;regulation of hormone levels#GO:0010817;cellular process#GO:0009987;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;biological regulation#GO:0065007;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;steroid metabolic process#GO:0008202;hormone metabolic process#GO:0042445 IXOSC|EnsemblGenome=LOC120847633|UniProtKB=A0ACM8G0J1 A0ACM8G0J1 LOC120847633 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8031705|UniProtKB=A0ACM8EFK3 A0ACM8EFK3 LOC8031705 PTHR23077:SF12 AAA-FAMILY ATPASE PEROXISOMAL ATPASE PEX1 ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;macromolecule localization#GO:0033036;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;intracellular protein transmembrane transport#GO:0065002;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;protein import into peroxisome matrix#GO:0016558;protein localization to organelle#GO:0033365;peroxisome organization#GO:0007031;protein transport#GO:0015031;peroxisomal transport#GO:0043574;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;microbody#GO:0042579;cytosol#GO:0005829;peroxisome#GO:0005777;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8039183|UniProtKB=A0ACM8FN11 A0ACM8FN11 LOC8039183 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034315|UniProtKB=A0ACM8F594 A0ACM8F594 LOC8034315 PTHR11360:SF251 MONOCARBOXYLATE TRANSPORTER KARMOISIN, ISOFORM B carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monocarboxylic acid transmembrane transporter activity#GO:0008028 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC120835958|UniProtKB=A0ACM8FBB2 A0ACM8FBB2 PTHR23117:SF13 GUANYLATE KINASE-RELATED GUANYLATE KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleobase-containing compound kinase activity#GO:0019205;phosphotransferase activity, phosphate group as acceptor#GO:0016776 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;purine ribonucleoside diphosphate metabolic process#GO:0009179;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;purine-containing compound biosynthetic process#GO:0072522;nucleoside diphosphate metabolic process#GO:0009132;purine nucleotide biosynthetic process#GO:0006164 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 kinase#PC00137;transferase#PC00220 De novo purine biosynthesis#P02738>Guanylate kinase#P02904 IXOSC|EnsemblGenome=LOC120836713|UniProtKB=A0ACM8EF98 A0ACM8EF98 LOC120836713 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027052|UniProtKB=A0ACM8DZB7 A0ACM8DZB7 LOC8027052 PTHR13580:SF14 TGF-BETA INDUCED APOPTOSIS PROTEIN CYSTEINE_SERINE-RICH NUCLEAR PROTEIN N-TERMINAL DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120847013|UniProtKB=A0ACM8F2X7 A0ACM8F2X7 LOC120847013 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 IXOSC|EnsemblGenome=LOC120840898|UniProtKB=A0ACM8EQB9 A0ACM8EQB9 LOC120840898 PTHR14221:SF72 WD REPEAT DOMAIN 44 WD REPEAT-CONTAINING PROTEIN 44 cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;cellular component assembly#GO:0022607;plasma membrane bounded cell projection assembly#GO:0120031;regulation of transport#GO:0051049;regulation of localization#GO:0032879;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627;cellular component organization#GO:0016043;cilium assembly#GO:0060271;regulation of cellular process#GO:0050794;cell projection organization#GO:0030030;organelle assembly#GO:0070925;cilium organization#GO:0044782 cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008 IXOSC|EnsemblGenome=LOC8024732|UniProtKB=A0ACM8E1J8 A0ACM8E1J8 LOC8024732 PTHR14738:SF29 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 14 RNA binding#GO:0003723;single-stranded RNA binding#GO:0003727;binding#GO:0005488;nucleic acid binding#GO:0003676;poly(A) binding#GO:0008143 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA stability#GO:0043488;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;regulation of biological quality#GO:0065008 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115315166|UniProtKB=A0ACM8EHC0 A0ACM8EHC0 LOC115315166 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8027700|UniProtKB=A0ACM8F8U3 A0ACM8F8U3 LOC8027700 PTHR24350:SF34 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;microtubule cytoskeleton organization#GO:0000226;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;cytoskeleton organization#GO:0007010;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 chromosome#GO:0005694;spindle pole#GO:0000922;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;spindle microtubule#GO:0005876;microtubule#GO:0005874;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120846283|UniProtKB=A0ACM8F1X7 A0ACM8F1X7 LOC120846283 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039868|UniProtKB=A0ACM8ES67 A0ACM8ES67 LOC8039868 PTHR11506:SF45 LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEIN 5 establishment of protein localization#GO:0045184;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;establishment of localization#GO:0051234 late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;lysosomal membrane#GO:0005765;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708;lytic vacuole membrane#GO:0098852;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC120842611|UniProtKB=A0ACM8EU03 A0ACM8EU03 LOC120842611 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8038099|UniProtKB=A0ACM8DIG7 A0ACM8DIG7 LOC8038099 PTHR46596:SF1 SORTING NEXIN-4 SORTING NEXIN-4 phosphatidylinositol-3-phosphate binding#GO:0032266;lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;binding#GO:0005488;phospholipid binding#GO:0005543 transport#GO:0006810;regulation of catabolic process#GO:0009894;intracellular protein localization#GO:0008104;regulation of macroautophagy#GO:0016241;establishment of localization#GO:0051234;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;establishment of protein localization#GO:0045184;regulation of organelle assembly#GO:1902115;regulation of metabolic process#GO:0019222;positive regulation of autophagy#GO:0010508;macromolecule localization#GO:0033036;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of cellular component organization#GO:0051130;regulation of autophagosome assembly#GO:2000785;protein transport#GO:0015031;positive regulation of organelle organization#GO:0010638;localization#GO:0051179;positive regulation of metabolic process#GO:0009893;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of autophagy#GO:0010506;regulation of cellular component biogenesis#GO:0044087;positive regulation of macroautophagy#GO:0016239;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;cell periphery#GO:0071944;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;early endosome membrane#GO:0031901 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120843957|UniProtKB=A0ACM8EXB2 A0ACM8EXB2 LOC120843957 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8038526|UniProtKB=A0ACM8DYK9 A0ACM8DYK9 wus PTHR44733:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 DNAJ HOMOLOG SUBFAMILY C MEMBER 22 cellular anatomical structure#GO:0110165;membrane#GO:0016020 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115320091|UniProtKB=A0ACM8F3Z3 A0ACM8F3Z3 LOC115320091 PTHR15301:SF12 INSULIN-INDUCED GENE 1 INSULIN-INDUCED GENE PROTEIN negative regulation of intracellular signal transduction#GO:1902532;regulation of cellular response to stress#GO:0080135;regulation of intracellular signal transduction#GO:1902531;cellular response to stress#GO:0033554;response to oxygen-containing compound#GO:1901700;small molecule metabolic process#GO:0044281;cellular response to endogenous stimulus#GO:0071495;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;metabolic process#GO:0008152;response to lipid#GO:0033993;response to chemical#GO:0042221;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;response to stress#GO:0006950;response to hormone#GO:0009725;cell communication#GO:0007154;localization#GO:0051179;intracellular signal transduction#GO:0035556;response to nitrogen compound#GO:1901698;cellular response to peptide hormone stimulus#GO:0071375;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;intracellular protein localization#GO:0008104;regulation of response to stress#GO:0080134;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;macromolecule localization#GO:0033036;cellular localization#GO:0051641;negative regulation of cell communication#GO:0010648;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;cellular response to hormone stimulus#GO:0032870;response to stimulus#GO:0050896;secondary alcohol metabolic process#GO:1902652;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;alcohol metabolic process#GO:0006066;cellular response to lipid#GO:0071396;cholesterol biosynthetic process#GO:0006695;negative regulation of signal transduction#GO:0009968;cellular process#GO:0009987;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;alcohol biosynthetic process#GO:0046165;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;secondary alcohol biosynthetic process#GO:1902653;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;cholesterol metabolic process#GO:0008203;cellular response to insulin stimulus#GO:0032869;lipid biosynthetic process#GO:0008610;negative regulation of response to stimulus#GO:0048585;response to peptide hormone#GO:0043434;SREBP signaling pathway#GO:0032933;biosynthetic process#GO:0009058;biological regulation#GO:0065007 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115330455|UniProtKB=A0ACM8EMG3 A0ACM8EMG3 LOC115330455 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8031796|UniProtKB=A0ACM8FW56 A0ACM8FW56 LOC8031796 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8039881|UniProtKB=A0ACM8DKG7 A0ACM8DKG7 PTHR46771:SF5 DETERIN DETERIN spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;chromosome segregation#GO:0007059;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;negative regulation of programmed cell death#GO:0043069;microtubule cytoskeleton organization#GO:0000226;cytoskeleton-dependent cytokinesis#GO:0061640;cytokinesis#GO:0000910;mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;mitotic cell cycle#GO:0000278;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;cell cycle#GO:0007049;cell division#GO:0051301;cell cycle process#GO:0022402;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;membraneless organelle#GO:0043228;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8030652|UniProtKB=A0ACM8DHC5 A0ACM8DHC5 LOC8030652 PTHR38926:SF87 F-BOX DOMAIN CONTAINING PROTEIN, EXPRESSED F-BOX AND LEUCINE-RICH REPEAT PROTEIN 6 binding#GO:0005488;protein-containing complex binding#GO:0044877 IXOSC|EnsemblGenome=LOC121836670|UniProtKB=A0ACM8G0H6 A0ACM8G0H6 LOC121836670 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120851096|UniProtKB=A0ACM8FB38 A0ACM8FB38 LOC120851096 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120848877|UniProtKB=A0ACM8G3X9 A0ACM8G3X9 LOC120848877 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837720|UniProtKB=A0ACM8G666 A0ACM8G666 LOC121837720 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121835521|UniProtKB=A0ACM8FVM7 A0ACM8FVM7 LOC121835521 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;heterochromatin organization#GO:0070828;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;cellular localization#GO:0051641;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;membrane organization#GO:0061024;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;organelle localization#GO:0051640;localization within membrane#GO:0051668;localization#GO:0051179 organelle#GO:0043226;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;intracellular organelle#GO:0043229 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC8042312|UniProtKB=A0ACM8ESD5 A0ACM8ESD5 LOC8042312 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310604|UniProtKB=A0ACM8F1Q0 A0ACM8F1Q0 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115326221|UniProtKB=A0ACM8ELZ5 A0ACM8ELZ5 LOC115326221 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121838028|UniProtKB=A0ACM8G7K0 A0ACM8G7K0 LOC121838028 PTHR11439:SF463 GAG-POL-RELATED RETROTRANSPOSON INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115321551|UniProtKB=A0ACM8F905 A0ACM8F905 LOC115321551 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8028736|UniProtKB=A0ACM8DN38 A0ACM8DN38 Naus PTHR23166:SF5 FILAMIN/GPBP-INTERACTING PROTEIN CTTNBP2 N-TERMINAL-LIKE PROTEIN localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to cytoskeleton#GO:0044380 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8041306|UniProtKB=A0ACM8FLJ0 A0ACM8FLJ0 PTHR12585:SF27 SCC1 / RAD21 FAMILY MEMBER MEIOTIC RECOMBINATION PROTEIN REC8 HOMOLOG binding#GO:0005488;chromatin binding#GO:0003682 response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;sister chromatid cohesion#GO:0007062;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;response to stress#GO:0006950;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694 IXOSC|EnsemblGenome=LOC8023126|UniProtKB=A0ACM8E393 A0ACM8E393 LOC8023126 PTHR12700:SF12 ATP SYNTHASE SUBUNIT D, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT D, MITOCHONDRIAL transporter activity#GO:0005215;ligase activity#GO:0016874;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;catalytic activity#GO:0003824;proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267 nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;organophosphate biosynthetic process#GO:0090407;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;small molecule metabolic process#GO:0044281;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793 proton-transporting two-sector ATPase complex#GO:0016469;cation channel complex#GO:0034703;transporter complex#GO:1990351;organelle membrane#GO:0031090;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;respiratory chain complex#GO:0098803;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;proton-transporting ATP synthase complex#GO:0045259;intracellular membrane-bounded organelle#GO:0043231 ATP synthase#PC00002;transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8026467|UniProtKB=A0ACM8DQI6 A0ACM8DQI6 LOC8026467 PTHR22576:SF37 MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1 cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC115309322|UniProtKB=A0ACM8DNQ0 A0ACM8DNQ0 LOC115309322 PTHR46830:SF2 TRANSFERASE, PUTATIVE-RELATED ALPHA-1,4-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase#PC00220 IXOSC|EnsemblGenome=LOC8030749|UniProtKB=A0ACM8E656 A0ACM8E656 LOC8030749 PTHR31918:SF2 TRANSMEMBRANE PROTEIN 181 TRANSMEMBRANE PROTEIN 181 regulation of signaling#GO:0023051;positive regulation of secretion#GO:0051047;positive regulation of signaling#GO:0023056;regulation of secretion#GO:0051046;regulation of secretion by cell#GO:1903530;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of protein secretion#GO:0050708;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of cell communication#GO:0010646;positive regulation of protein secretion#GO:0050714;regulation of transport#GO:0051049;regulation of localization#GO:0032879;positive regulation of secretion by cell#GO:1903532;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;biological regulation#GO:0065007 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC121833239|UniProtKB=A0ACM8FIQ1 A0ACM8FIQ1 LOC121833239 PTHR47027:SF32 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052446|UniProtKB=A0ACM8EDA6 A0ACM8EDA6 Gpdh1 PTHR11728:SF8 GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLYCEROL-3-PHOSPHATE DEHYDROGENASE [NAD(+)]-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8038817|UniProtKB=A0ACM8DY05 A0ACM8DY05 LOC8038817 PTHR11941:SF179 ENOYL-COA HYDRATASE-RELATED ENOYL-COA HYDRATASE, MITOCHONDRIAL oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 lyase#PC00144;hydratase#PC00120;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8044074|UniProtKB=A0ACM8DQD2 A0ACM8DQD2 LOC8044074 PTHR31872:SF4 TRANSMEMBRANE PROTEIN 179 TRANSMEMBRANE PROTEIN 179 IXOSC|EnsemblGenome=LOC8053354|UniProtKB=A0ACM8DPW7 A0ACM8DPW7 mus201 PTHR16171:SF7 DNA REPAIR PROTEIN COMPLEMENTING XP-G CELLS-RELATED XPG (XERODERMA PIGMENTOSUM GROUP G) DNA REPAIR GENE HOMOLOG endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stimulus#GO:0050896 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;nucleotide-excision repair complex#GO:0000109;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8043292|UniProtKB=A0ACM8DL41 A0ACM8DL41 LOC8043292 PTHR45902:SF7 LATROPHILIN RECEPTOR-LIKE PROTEIN A G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115322555|UniProtKB=A0ACM8E3E0 A0ACM8E3E0 LOC115322555 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115325027|UniProtKB=A0ACM8E5B2 A0ACM8E5B2 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8031244|UniProtKB=A0ACM8DI26 A0ACM8DI26 LOC8031244 PTHR14725:SF0 RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED RIBOSOME-BINDING FACTOR A, MITOCHONDRIAL-RELATED IXOSC|EnsemblGenome=LOC120850874|UniProtKB=A0ACM8F9X4 A0ACM8F9X4 LOC120850874 PTHR22970:SF14 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ATPase complex#GO:1904949;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8034211|UniProtKB=A0ACM8EFF4 A0ACM8EFF4 LOC8034211 PTHR45867:SF3 PURPLE ACID PHOSPHATASE ACID PHOSPHATASE TYPE 7 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8051318|UniProtKB=A0ACM8DPH1 A0ACM8DPH1 ATP6AP2 PTHR13351:SF1 RENIN RECEPTOR RENIN RECEPTOR regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;positive regulation of signal transduction#GO:0009967;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;positive regulation of Wnt signaling pathway#GO:0030177;positive regulation of response to stimulus#GO:0048584;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 membrane#GO:0016020;cell periphery#GO:0071944;external side of plasma membrane#GO:0009897;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8026257|UniProtKB=A0ACM8EKD6 A0ACM8EKD6 PTHR15067:SF5 E3 UBIQUITIN-PROTEIN LIGASE RNF8 E3 UBIQUITIN-PROTEIN LIGASE AMFR transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 protein ubiquitination#GO:0016567;response to stress#GO:0006950;signal transduction#GO:0007165;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;response to unfolded protein#GO:0006986;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein K48-linked ubiquitination#GO:0070936;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8031583|UniProtKB=A0ACM8ELD9 A0ACM8ELD9 MED21 PTHR13381:SF0 RNA POLYMERASE II HOLOENZYME COMPONENT SRB7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 21 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8053115|UniProtKB=A0ACM8E8P4 A0ACM8E8P4 LOC8053115 PTHR10334:SF578 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC120850417|UniProtKB=A0ACM8FAS4 A0ACM8FAS4 LOC120850417 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8052323|UniProtKB=A0ACM8F910 A0ACM8F910 LOC8052323 PTHR45625:SF2 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 3 peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8027161|UniProtKB=A0ACM8FNK2 A0ACM8FNK2 PTHR13609:SF4 UBIQUITIN DOMAIN CONTAINING 1 PROTEIN-RELATED RE42193P ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120843005|UniProtKB=A0ACM8EV49 A0ACM8EV49 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8038485|UniProtKB=A0ACM8G3S5 A0ACM8G3S5 LOC8038485 PTHR46379:SF1 ZINC FINGER MYND DOMAIN-CONTAINING ZINC FINGER MYND DOMAIN-CONTAINING PROTEIN 11 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;histone H3 reader activity#GO:0140006;protein-macromolecule adaptor activity#GO:0030674 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;transcription by RNA polymerase II#GO:0006366;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription elongation#GO:0006354;chromatin organization#GO:0006325;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC8030389|UniProtKB=A0ACM8FFE9 A0ACM8FFE9 LOC8030389 PTHR10799:SF964 SNF2/RAD54 HELICASE FAMILY SWI_SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A CONTAINING DEAD_H BOX 1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;chromatin binding#GO:0003682;ATP-dependent activity#GO:0140657;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677;ATP-dependent activity, acting on DNA#GO:0008094 heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;double-strand break repair#GO:0006302;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;positive regulation of transcription by RNA polymerase II#GO:0045944;metabolic process#GO:0008152;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to stress#GO:0033554;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;DNA double-strand break processing#GO:0000729;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;heterochromatin formation#GO:0031507;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8029513|UniProtKB=A0ACM8E3G8 A0ACM8E3G8 B9d1 PTHR12968:SF1 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 1 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030 membrane-bounded organelle#GO:0043227;ciliary transition zone#GO:0035869;cilium#GO:0005929;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 structural protein#PC00211 IXOSC|EnsemblGenome=LOC120838215|UniProtKB=A0ACM8EIS9 A0ACM8EIS9 LOC120838215 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115332980|UniProtKB=A0ACM8EEC0 A0ACM8EEC0 LOC115332980 PTHR13005:SF4 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC121836113|UniProtKB=A0ACM8FYL1 A0ACM8FYL1 LOC121836113 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC8040799|UniProtKB=A0ACM8EC70 A0ACM8EC70 LOC8040799 PTHR14624:SF0 DFG10 PROTEIN POLYPRENAL REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8029027|UniProtKB=A0ACM8E199 A0ACM8E199 ArfGAP3 PTHR45686:SF4 ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H-RELATED ADP-RIBOSYLATION FACTOR GTPASE ACTIVATING PROTEIN 3, ISOFORM H Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024 GTPase-activating protein#PC00257;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC121832869|UniProtKB=A0ACM8FZZ0 A0ACM8FZZ0 LOC121832869 PTHR19303:SF82 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120849961|UniProtKB=A0ACM8F8S1 A0ACM8F8S1 LOC120849961 PTHR10590:SF24 SODIUM/NUCLEOSIDE COTRANSPORTER CONCENTRATIVE NUCLEOSIDE TRANSPORTER 1-RELATED secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;nucleoside transmembrane transporter activity#GO:0005337;symporter activity#GO:0015293;monoatomic cation transmembrane transporter activity#GO:0008324;carbohydrate derivative transmembrane transporter activity#GO:1901505;solute:sodium symporter activity#GO:0015370;nucleobase-containing compound transmembrane transporter activity#GO:0015932 nucleobase-containing compound transport#GO:0015931;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8035074|UniProtKB=A0ACM8E8C4 A0ACM8E8C4 LOC8035074 PTHR16458:SF2 GLYCINE N-METHYLTRANSFERASE GLYCINE N-METHYLTRANSFERASE N-methyltransferase activity#GO:0008170;transferase activity#GO:0016740;catalytic activity#GO:0003824;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;oxoacid metabolic process#GO:0043436;purine nucleoside metabolic process#GO:0042278;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115330504|UniProtKB=A0ACM8EWL4 A0ACM8EWL4 LOC115330504 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC121833441|UniProtKB=A0ACM8FL43 A0ACM8FL43 LOC121833441 PTHR11537:SF289 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAB transporter regulator activity#GO:0141108;potassium channel regulator activity#GO:0015459;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772 cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;transport#GO:0006810;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;action potential#GO:0001508;metal ion transport#GO:0030001;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 ion channel#PC00133;voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC8033145|UniProtKB=A0ACM8G0H9 A0ACM8G0H9 LOC8033145 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8026889|UniProtKB=A0ACM8DIJ7 A0ACM8DIJ7 LOC8026889 PTHR11588:SF504 TUBULIN TUBULIN BETA-1 CHAIN-RELATED ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 cell cycle#GO:0007049;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017 microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874 cytoskeletal protein#PC00085;tubulin#PC00228 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 IXOSC|EnsemblGenome=LOC8051154|UniProtKB=A0ACM8DNU3 A0ACM8DNU3 LOC8051154 PTHR13559:SF1 INTRACELLULAR TRAFFIC PROTEIN-RELATED PROTEIN FUZZY HOMOLOG organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component organization or biogenesis#GO:0071840;non-motile cilium assembly#GO:1905515;cilium organization#GO:0044782;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection assembly#GO:0030031;cellular process#GO:0009987;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036 IXOSC|EnsemblGenome=LOC8051603|UniProtKB=A0ACM8DTZ1 A0ACM8DTZ1 LOC8051603 PTHR46024:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;heterochromatin organization#GO:0070828;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8024530|UniProtKB=A0ACM8FUR2 A0ACM8FUR2 LOC8024530 PTHR10288:SF347 KH DOMAIN CONTAINING RNA BINDING PROTEIN MUSHROOM-BODY EXPRESSED, ISOFORM K RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8038369|UniProtKB=A0ACM8EBG3 A0ACM8EBG3 LOC8038369 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;alpha-glucosidase activity#GO:0090599;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;catalytic activity#GO:0003824 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC8034764|UniProtKB=A0ACM8EI61 A0ACM8EI61 Nipped-A PTHR11139:SF1 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;DNA damage response#GO:0006974;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987 SAGA complex#GO:0000124;nucleus#GO:0005634;chromatin#GO:0000785;NuA4 histone acetyltransferase complex#GO:0035267;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;peptidase complex#GO:1905368;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;SAGA-type complex#GO:0070461;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8039106|UniProtKB=A0ACM8DKB0 A0ACM8DKB0 PTHR12814:SF2 RNA-BINDING PROTEIN NOB1 RNA-BINDING PROTEIN NOB1 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;RNA nuclease activity#GO:0004540;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;biosynthetic process#GO:0009058;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC120837626|UniProtKB=A0ACM8EHU1 A0ACM8EHU1 LOC120837626 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028301|UniProtKB=A0ACM8G0E9 A0ACM8G0E9 LOC8028301 PTHR24211:SF37 LIM DOMAIN-CONTAINING PROTEIN PROTEIN ESPINAS-LIKE PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115325330|UniProtKB=A0ACM8FAI7 A0ACM8FAI7 LOC115325330 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053309|UniProtKB=A0ACM8EB79 A0ACM8EB79 LOC8053309 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;ornithine decarboxylase activity#GO:0004586;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC115324150|UniProtKB=A0ACM8FAY5 A0ACM8FAY5 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC121833595|UniProtKB=A0ACM8FLT0 A0ACM8FLT0 LOC121833595 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052727|UniProtKB=A0ACM8DQ90 A0ACM8DQ90 PTHR16222:SF24 ADP-RIBOSYLGLYCOHYDROLASE ADP-RIBOSYLHYDROLASE ARH3 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;response to reactive oxygen species#GO:0000302;metabolic process#GO:0008152;response to chemical#GO:0042221;cellular response to oxidative stress#GO:0034599;response to stress#GO:0006950;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;mitochondrion#GO:0005739 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120840075|UniProtKB=A0ACM8ENQ4 A0ACM8ENQ4 LOC120840075 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC115327980|UniProtKB=A0ACM8E859 A0ACM8E859 LOC115327980 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8036527|UniProtKB=A0ACM8DUP4 A0ACM8DUP4 LOC8036527 PTHR18947:SF40 HOOK PROTEINS GIRDIN, ISOFORM A protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cellular component organization#GO:0016043;cytoplasmic microtubule organization#GO:0031122;supramolecular fiber organization#GO:0097435;cellular localization#GO:0051641;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115314960|UniProtKB=A0ACM8ERH3 A0ACM8ERH3 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121046804|UniProtKB=A0ACM8FV45 A0ACM8FV45 LOC121046804 PTHR13371:SF0 GLYCINE-, GLUTAMATE-, THIENYLCYCLOHEXYLPIPERIDINE-BINDING PROTEIN CENTROSOMAL PROTEIN OF 104 KDA cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 IXOSC|EnsemblGenome=LOC8043348|UniProtKB=A0ACM8DL51 A0ACM8DL51 LOC8043348 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;protein folding#GO:0006457;response to stimulus#GO:0050896;protein refolding#GO:0042026;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to heat#GO:0009408;response to stress#GO:0006950;response to temperature stimulus#GO:0009266;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC115330545|UniProtKB=A0ACM8F4G2 A0ACM8F4G2 LOC115330545 PTHR10943:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;endopeptidase complex#GO:1905369;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;nucleus#GO:0005634;proteasome complex#GO:0000502 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC115311099|UniProtKB=A0ACM8DQG9 A0ACM8DQG9 Ccz1 PTHR13056:SF0 VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED VACUOLAR FUSION PROTEIN CCZ1 HOMOLOG-RELATED nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179 cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;late endosome#GO:0005770;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;guanyl-nucleotide exchange factor complex#GO:0032045 IXOSC|EnsemblGenome=LOC8029740|UniProtKB=A0ACM8E485 A0ACM8E485 LOC8029740 PTHR21448:SF0 SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115318301|UniProtKB=A0ACM8DYA8 A0ACM8DYA8 LOC115318301 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121835577|UniProtKB=A0ACM8FUZ8 A0ACM8FUZ8 LOC121835577 PTHR24133:SF60 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT AND SOCS BOX-CONTAINING 3 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120845273|UniProtKB=A0ACM8F1D8 A0ACM8F1D8 LOC120845273 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309645|UniProtKB=A0ACM8DNW6 A0ACM8DNW6 LOC115309645 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152;cellular process#GO:0009987;carnitine metabolic process#GO:0009437 peroxisome#GO:0005777;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8030228|UniProtKB=A0ACM8DGH4 A0ACM8DGH4 Dph3 PTHR21454:SF31 DPH3 HOMOLOG-RELATED DIPHTHAMIDE BIOSYNTHESIS PROTEIN 3 ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;iron ion binding#GO:0005506;cation binding#GO:0043169 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8028533|UniProtKB=A0ACM8F2C6 A0ACM8F2C6 LOC8028533 PTHR19288:SF93 4-NITROPHENYLPHOSPHATASE-RELATED FI11325P-RELATED phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120836322|UniProtKB=A0ACM8F1S6 A0ACM8F1S6 LOC120836322 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120848518|UniProtKB=A0ACM8F670 A0ACM8F670 LOC120848518 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842457|UniProtKB=A0ACM8ETV8 A0ACM8ETV8 LOC120842457 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308980|UniProtKB=A0ACM8G647 A0ACM8G647 LOC115308980 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120845846|UniProtKB=A0ACM8F0Y9 A0ACM8F0Y9 LOC120845846 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8030905|UniProtKB=A0ACM8E5Y0 A0ACM8E5Y0 nst PTHR45955:SF1 PHOSPHOACETYLGLUCOSAMINE MUTASE PHOSPHOACETYLGLUCOSAMINE MUTASE isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;intramolecular phosphotransferase activity#GO:0016868 nucleotide-sugar metabolic process#GO:0009225;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;amino sugar metabolic process#GO:0006040;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate biosynthetic process#GO:0090407;UDP-N-acetylglucosamine metabolic process#GO:0006047;UDP-N-acetylglucosamine biosynthetic process#GO:0006048 mutase#PC00160;isomerase#PC00135 IXOSC|EnsemblGenome=LOC8028919|UniProtKB=A0ACM8E967 A0ACM8E967 LOC8028919 PTHR22742:SF2 EXPANSION, ISOFORM A-RELATED EXPANSION, ISOFORM A-RELATED IXOSC|EnsemblGenome=LOC8024636|UniProtKB=A0ACM8E7P3 A0ACM8E7P3 LOC8024636 PTHR22792:SF140 LUPUS LA PROTEIN-RELATED ACHILLES, ISOFORM A nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121047566|UniProtKB=A0ACM8FHC3 A0ACM8FHC3 LOC121047566 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8031492|UniProtKB=A0ACM8EE93 A0ACM8EE93 LOC8031492 PTHR14222:SF1 CONDENSIN CONDENSIN-2 COMPLEX SUBUNIT D3 protein binding#GO:0005515;histone binding#GO:0042393;binding#GO:0005488 chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;chromosome organization involved in meiotic cell cycle#GO:0070192;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;sexual reproduction#GO:0019953;nuclear division#GO:0000280;chromosome condensation#GO:0030261;mitotic chromosome condensation#GO:0007076;organelle fission#GO:0048285;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;sister chromatid segregation#GO:0000819;cell cycle#GO:0007049;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;condensin complex#GO:0000796;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8023930|UniProtKB=A0ACM8E128 A0ACM8E128 LOC8023930 PTHR39952:SF1 FI02073P SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115320838|UniProtKB=A0ACM8G4Q8 A0ACM8G4Q8 LOC115320838 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115308294|UniProtKB=A0ACM8DMC4 A0ACM8DMC4 LOC115308294 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030759|UniProtKB=A0ACM8E495 A0ACM8E495 LOC8030759 PTHR23024:SF574 ARYLACETAMIDE DEACETYLASE KYNURENINE FORMAMIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid catabolic process#GO:0046395;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 deacetylase#PC00087 IXOSC|EnsemblGenome=LOC8037793|UniProtKB=A0ACM8EBT5 A0ACM8EBT5 LOC8037793 PTHR47961:SF6 DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED DEXH-BOX ATP-DEPENDENT RNA HELICASE DEXH15 CHLOROPLASTIC recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;double-strand break repair via single-strand annealing#GO:0045002;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115312734|UniProtKB=A0ACM8G706 A0ACM8G706 LOC115312734 PTHR10822:SF30 GLYPICAN DALLY-LIKE, ISOFORM A regulation of biological process#GO:0050789;regulation of protein localization to membrane#GO:1905475;cellular process#GO:0009987;biological regulation#GO:0065007;cell migration#GO:0016477;regulation of cellular process#GO:0050794;cell motility#GO:0048870;regulation of localization#GO:0032879;regulation of protein localization#GO:0032880 cell junction#GO:0030054;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;synapse#GO:0045202;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120841554|UniProtKB=A0ACM8ESW6 A0ACM8ESW6 LOC120841554 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318063|UniProtKB=A0ACM8EFW8 A0ACM8EFW8 RpL37a PTHR10768:SF0 60S RIBOSOMAL PROTEIN L37 RIBOSOMAL PROTEIN L37 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115316754|UniProtKB=A0ACM8DWC3 A0ACM8DWC3 LOC115316754 PTHR24241:SF190 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR CARDIOACCELERATORY PEPTIDE RECEPTOR-LIKE PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8041797|UniProtKB=A0ACM8ED33 A0ACM8ED33 LOC8041797 PTHR19282:SF252 TETRASPANIN TETRASPANIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120836984|UniProtKB=A0ACM8EGC4 A0ACM8EGC4 LOC120836984 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035322|UniProtKB=A0ACM8DY50 A0ACM8DY50 LOC8035322 PTHR46010:SF1 PROTEIN IWS1 HOMOLOG PROTEIN IWS1 HOMOLOG establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;metabolic process#GO:0008152;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;macromolecule metabolic process#GO:0043170;poly(A)+ mRNA export from nucleus#GO:0016973;establishment of localization#GO:0051234;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC120838267|UniProtKB=A0ACM8EIV6 A0ACM8EIV6 LOC120838267 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036371|UniProtKB=A0ACM8FTM6 A0ACM8FTM6 LOC8036371 PTHR46180:SF1 VINCULIN VINCULIN binding#GO:0005488;beta-catenin binding#GO:0008013;protein binding#GO:0005515 cell adhesion#GO:0007155;cellular process#GO:0009987 cytoskeleton#GO:0005856;cell-cell contact zone#GO:0044291;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;organelle#GO:0043226 Gonadotropin-releasing hormone receptor pathway#P06664>Vinculin#P06771;Integrin signalling pathway#P00034>Vinculin#P00937 IXOSC|EnsemblGenome=LOC120846745|UniProtKB=A0ACM8F2B1 A0ACM8F2B1 LOC120846745 PTHR18952:SF278 CARBONIC ANHYDRASE CARBONIC ANHYDRASE catalytic activity#GO:0003824;hydro-lyase activity#GO:0016836;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 IXOSC|EnsemblGenome=LOC120844840|UniProtKB=A0ACM8EZT0 A0ACM8EZT0 PTHR22984:SF33 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE 1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cellular process#GO:0050794;negative regulation of apoptotic process#GO:0043066;regulation of mitotic cell cycle#GO:0007346;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8039530|UniProtKB=A0ACM8E4B0 A0ACM8E4B0 Ssadh PTHR43353:SF14 SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 Gamma-aminobutyric acid synthesis#P04384>Succinic semialdehyde dehydrogenase#P04481;Aminobutyrate degradation#P02726>Succinate semi-aldehyde dehydrogenase#P02824 IXOSC|EnsemblGenome=LOC8042377|UniProtKB=A0ACM8E2X1 A0ACM8E2X1 LOC8042377 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8029346|UniProtKB=A0ACM8FKI2 A0ACM8FKI2 LOC8029346 PTHR14396:SF10 CLASPIN CLASPIN IXOSC|EnsemblGenome=LOC8024571|UniProtKB=A0ACM8EC76 A0ACM8EC76 slgA PTHR13914:SF0 PROLINE OXIDASE PROLINE DEHYDROGENASE-RELATED anion binding#GO:0043168;flavin adenine dinucleotide binding#GO:0050660;small molecule binding#GO:0036094;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidase#PC00175 Huntington disease#P00029>Proline oxidase#G01529 IXOSC|EnsemblGenome=LOC120839543|UniProtKB=A0ACM8ELY9 A0ACM8ELY9 LOC120839543 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115314396|UniProtKB=A0ACM8DU17 A0ACM8DU17 LOC115314396 PTHR12812:SF0 HEPARAN SULFATE 6-O-SULFOTRANSFERASE 3 HEPARAN-SULFATE 6-O-SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteoglycan metabolic process#GO:0006029;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058 transferase#PC00220 IXOSC|EnsemblGenome=LOC8033969|UniProtKB=A0ACM8DIM6 A0ACM8DIM6 LOC8033969 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC121046393|UniProtKB=A0ACM8FE23 A0ACM8FE23 LOC121046393 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115311428|UniProtKB=A0ACM8FVR3 A0ACM8FVR3 LOC115311428 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039963|UniProtKB=A0ACM8F6A3 A0ACM8F6A3 PTHR48051:SF52 FAMILY NOT NAMED LEUCINE-RICH REPEAT PROTEIN 1 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8054029|UniProtKB=A0ACM8DVK5 A0ACM8DVK5 LOC8054029 PTHR18945:SF898 NEUROTRANSMITTER GATED ION CHANNEL GLUTAMATE-GATED CHLORIDE CHANNEL channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8041489|UniProtKB=A0ACM8ECV5 A0ACM8ECV5 orb PTHR12566:SF9 CYTOPLASMIC POLYADENYLATION ELEMENT BINDING PROTEIN CPEB CYTOPLASMIC POLYADENYLATION ELEMENT-BINDING PROTEIN 1 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021;translation factor activity#GO:0180051;mRNA 3'-UTR binding#GO:0003730;translation regulator activity#GO:0045182 negative regulation of translation#GO:0017148;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558 organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;intracellular membrane-bounded organelle#GO:0043231;plasma membrane bounded cell projection#GO:0120025;cytoplasm#GO:0005737;neuron projection#GO:0043005;nucleus#GO:0005634;cell junction#GO:0030054;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC120851156|UniProtKB=A0ACM8FL20 A0ACM8FL20 LOC120851156 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8036023|UniProtKB=A0ACM8FT91 A0ACM8FT91 LOC8036023 PTHR46957:SF3 CYTOKINE RECEPTOR PROTEIN-TYROSINE-PHOSPHATASE transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121837189|UniProtKB=A0ACM8G400 A0ACM8G400 LOC121837189 PTHR45168:SF3 DNAJ HOMOLOG SUBFAMILY B MEMBER 2 DNAJ HOMOLOG SUBFAMILY B MEMBER 6-LIKE ISOFORM X1 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8051871|UniProtKB=A0ACM8EAT4 A0ACM8EAT4 LOC8051871 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120847684|UniProtKB=A0ACM8F4G5 A0ACM8F4G5 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8025717|UniProtKB=A0ACM8DNE8 A0ACM8DNE8 PTHR24082:SF473 NUCLEAR HORMONE RECEPTOR ECDYSONE-INDUCED PROTEIN 75B, ISOFORM B sequence-specific DNA binding#GO:0043565;signaling receptor activity#GO:0038023;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676 cellular response to stimulus#GO:0051716;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;response to endogenous stimulus#GO:0009719;negative regulation of metabolic process#GO:0009892;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to chemical stimulus#GO:0070887;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;hormone-mediated signaling pathway#GO:0009755;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;response to hormone#GO:0009725;negative regulation of macromolecule biosynthetic process#GO:0010558;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C4 zinc finger nuclear receptor#PC00169 IXOSC|EnsemblGenome=LOC115327010|UniProtKB=A0ACM8FK35 A0ACM8FK35 LOC115327010 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8039938|UniProtKB=A0ACM8DRI8 A0ACM8DRI8 LOC8039938 PTHR11920:SF335 GUANYLYL CYCLASE GUANYLATE CYCLASE lyase activity#GO:0016829;molecular transducer activity#GO:0060089;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;peptide receptor activity#GO:0001653 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanylate cyclase#PC00114;lyase#PC00144 IXOSC|EnsemblGenome=LOC8028152|UniProtKB=A0ACM8E0F6 A0ACM8E0F6 LOC8028152 PTHR10177:SF344 CYCLINS G1_S-SPECIFIC CYCLIN-E enzyme regulator activity#GO:0030234;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle process#GO:1903047;positive regulation of mitotic cell cycle#GO:0045931;positive regulation of cell cycle G1/S phase transition#GO:1902808;G1/S transition of mitotic cell cycle#GO:0000082;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;positive regulation of cell cycle#GO:0045787;positive regulation of biological process#GO:0048518;cell cycle G1/S phase transition#GO:0044843;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of G1/S transition of mitotic cell cycle#GO:2000045;mitotic cell cycle phase transition#GO:0044772;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;cell cycle process#GO:0022402;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554 kinase activator#PC00138 p53 pathway feedback loops 2#P04398>cyclin E#P04664;Cell cycle#P00013>Cyclin E#P00483;Cell cycle#P00013>CdkC#P00489;p53 pathway#P00059>Cyclin E#P04610 IXOSC|EnsemblGenome=LOC115329017|UniProtKB=A0ACM8E9W9 A0ACM8E9W9 LOC115329017 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115326194|UniProtKB=A0ACM8E5M3 A0ACM8E5M3 LOC115326194 PTHR10857:SF106 COPINE NICOTINIC RECEPTOR-ASSOCIATED PROTEIN 1 lipid binding#GO:0008289;binding#GO:0005488;phospholipid binding#GO:0005543 response to chemical#GO:0042221;response to stimulus#GO:0050896;response to calcium ion#GO:0051592;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to metal ion#GO:0010038 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC115318551|UniProtKB=A0ACM8FVP1 A0ACM8FVP1 LOC115318551 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121046067|UniProtKB=A0ACM8FDX8 A0ACM8FDX8 LOC121046067 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833521|UniProtKB=A0ACM8FLH6 A0ACM8FLH6 LOC121833521 PTHR23048:SF66 MYOSIN LIGHT CHAIN 1, 3 CALMODULIN 2 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;myosin complex#GO:0016459;actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC115326314|UniProtKB=A0ACM8EIE8 A0ACM8EIE8 LOC115326314 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838226|UniProtKB=A0ACM8G6W4 A0ACM8G6W4 LOC121838226 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330634|UniProtKB=A0ACM8EU12 A0ACM8EU12 LOC115330634 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029321|UniProtKB=A0ACM8E2L0 A0ACM8E2L0 LOC8029321 PTHR10913:SF13 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 1 cellular developmental process#GO:0048869;cell differentiation#GO:0030154;cellular process#GO:0009987;developmental process#GO:0032502 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 Cadherin signaling pathway#P00012>Wnt#P00474;Wnt signaling pathway#P00057>Wnt#P01444;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142 IXOSC|EnsemblGenome=LOC121837831|UniProtKB=A0ACM8G5B5 A0ACM8G5B5 LOC121837831 PTHR11590:SF40 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE HEMOCYTE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 transferase#PC00220 IXOSC|EnsemblGenome=LOC121834629|UniProtKB=A0ACM8FRF8 A0ACM8FRF8 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115322472|UniProtKB=A0ACM8ERB7 A0ACM8ERB7 LOC115322472 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041556|UniProtKB=A0ACM8EL81 A0ACM8EL81 LOC8041556 PTHR10404:SF84 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8031117|UniProtKB=A0ACM8DVB0 A0ACM8DVB0 LOC8031117 PTHR11532:SF73 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180 primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 IXOSC|EnsemblGenome=LOC120838552|UniProtKB=A0ACM8EK18 A0ACM8EK18 LOC120838552 PTHR19282:SF478 TETRASPANIN TETRASPANIN cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8052150|UniProtKB=A0ACM8G1I4 A0ACM8G1I4 LOC8052150 PTHR10913:SF14 FOLLISTATIN-RELATED FOLLISTATIN-RELATED PROTEIN 5-LIKE PROTEIN cellular process#GO:0009987;developmental process#GO:0032502;cellular developmental process#GO:0048869;cell differentiation#GO:0030154 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8026728|UniProtKB=A0ACM8EUY7 A0ACM8EUY7 LOC8026728 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8034316|UniProtKB=A0ACM8FSM8 A0ACM8FSM8 LOC8034316 PTHR12231:SF278 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN KAPPA, ISOFORM A cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155;synapse organization#GO:0050808 neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253;cell junction#GO:0030054 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115318080|UniProtKB=A0ACM8FH20 A0ACM8FH20 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844505|UniProtKB=A0ACM8EYJ3 A0ACM8EYJ3 LOC120844505 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115314635|UniProtKB=A0ACM8DUJ9 A0ACM8DUJ9 LOC115314635 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844729|UniProtKB=A0ACM8EZD2 A0ACM8EZD2 LOC120844729 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8034511|UniProtKB=A0ACM8DSU1 A0ACM8DSU1 LOC8034511 PTHR28593:SF3 METEORIN-LIKE PROTEIN METEORIN-LIKE PROTEIN signaling receptor activator activity#GO:0030546;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC121834650|UniProtKB=A0ACM8FQB4 A0ACM8FQB4 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332824|UniProtKB=A0ACM8FYR7 A0ACM8FYR7 LOC115332824 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;monoatomic cation transmembrane transporter activity#GO:0008324 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8042683|UniProtKB=A0ACM8F6L3 A0ACM8F6L3 LOC8042683 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121835087|UniProtKB=A0ACM8FS88 A0ACM8FS88 LOC121835087 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837684|UniProtKB=A0ACM8EHZ6 A0ACM8EHZ6 LOC120837684 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121833684|UniProtKB=A0ACM8FN56 A0ACM8FN56 LOC121833684 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8030511|UniProtKB=A0ACM8DXD5 A0ACM8DXD5 LOC8030511 PTHR10024:SF364 SYNAPTOTAGMIN C2 DOMAIN-CONTAINING PROTEIN phospholipid binding#GO:0005543;binding#GO:0005488;SNARE binding#GO:0000149;molecular sensor activity#GO:0140299;lipid binding#GO:0008289;molecular function regulator activity#GO:0098772;protein binding#GO:0005515 biological regulation#GO:0065007;vesicle-mediated transport#GO:0016192;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of exocytosis#GO:0017157;regulation of secretion by cell#GO:1903530;localization#GO:0051179;regulation of secretion#GO:0051046;establishment of localization#GO:0051234;transport#GO:0006810 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cell periphery#GO:0071944;secretory vesicle#GO:0099503;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;endomembrane system#GO:0012505;transport vesicle#GO:0030133 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8026701|UniProtKB=A0ACM8F562 A0ACM8F562 LOC8026701 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8043478|UniProtKB=A0ACM8EGW7 A0ACM8EGW7 LOC8043478 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115331389|UniProtKB=A0ACM8EG03 A0ACM8EG03 LOC115331389 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8032135|UniProtKB=A0ACM8DTP3 A0ACM8DTP3 LOC8032135 PTHR15696:SF0 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 TELOMERASE-BINDING PROTEIN EST1A DNA binding#GO:0003677;RNA binding#GO:0003723;telomeric repeat DNA binding#GO:0042162;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676 primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115320444|UniProtKB=A0ACM8E047 A0ACM8E047 LOC115320444 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8041557|UniProtKB=A0ACM8DZD0 A0ACM8DZD0 mRpL14 PTHR21037:SF3 39S RIBOSOMAL PROTEIN L14, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL14M intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120840459|UniProtKB=A0ACM8EPK5 A0ACM8EPK5 LOC120840459 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115317640|UniProtKB=A0ACM8DXT2 A0ACM8DXT2 LOC115317640 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC115323878|UniProtKB=A0ACM8EJ77 A0ACM8EJ77 LOC115323878 PTHR11096:SF0 RNA 3' TERMINAL PHOSPHATE CYCLASE RNA 3'-TERMINAL PHOSPHATE CYCLASE cyclase activity#GO:0009975;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8036124|UniProtKB=A0ACM8DYN0 A0ACM8DYN0 LOC8036124 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC115316328|UniProtKB=A0ACM8EYU8 A0ACM8EYU8 LOC115316328 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8030713|UniProtKB=A0ACM8DUJ7 A0ACM8DUJ7 LOC8030713 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8035519|UniProtKB=A0ACM8DJU7 A0ACM8DJU7 LOC8035519 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115320338|UniProtKB=A0ACM8E0P8 A0ACM8E0P8 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024945|UniProtKB=A0ACM8DIU3 A0ACM8DIU3 ari-1 PTHR11685:SF475 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE ARIH1 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;binding#GO:0005488;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;enzyme binding#GO:0019899;ubiquitin-like protein transferase activity#GO:0019787 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8029791|UniProtKB=A0ACM8DIT6 A0ACM8DIT6 LOC8029791 PTHR11595:SF92 EF-HAND AND COILED-COIL DOMAIN-CONTAINING FAMILY MEMBER ELONGATION FACTOR 1-BETA molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC120838011|UniProtKB=A0ACM8FNI2 A0ACM8FNI2 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029600|UniProtKB=A0ACM8EPV6 A0ACM8EPV6 LOC8029600 PTHR13832:SF883 PROTEIN PHOSPHATASE 2C INTEGRIN-LINKED KINASE-ASSOCIATED SERINE_THREONINE PHOSPHATASE 2C catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC115318820|UniProtKB=A0ACM8EP58 A0ACM8EP58 LOC115318820 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8041501|UniProtKB=A0ACM8DKQ0 A0ACM8DKQ0 LOC8041501 PTHR22961:SF16 SER/THR PROTEIN KINASE-TRB SERINE_THREONINE-PROTEIN KINASE 40 regulation of intracellular signal transduction#GO:1902531;regulation of MAPK cascade#GO:0043408;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120846730|UniProtKB=A0ACM8F325 A0ACM8F325 LOC120846730 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029653|UniProtKB=A0ACM8EEQ4 A0ACM8EEQ4 LOC8029653 PTHR19303:SF78 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115320384|UniProtKB=A0ACM8E069 A0ACM8E069 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121835974|UniProtKB=A0ACM8FWK7 A0ACM8FWK7 LOC121835974 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120841556|UniProtKB=A0ACM8ERS5 A0ACM8ERS5 LOC120841556 PTHR21016:SF1 BETA-AMYLOID BINDING PROTEIN-RELATED TM2 DOMAIN-CONTAINING PROTEIN 1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 positive regulation of signaling#GO:0023056;cell communication#GO:0007154;regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;positive regulation of Notch signaling pathway#GO:0045747;regulation of cell communication#GO:0010646;signaling#GO:0023052;programmed cell death#GO:0012501;positive regulation of signal transduction#GO:0009967;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219;regulation of biological process#GO:0050789;apoptotic signaling pathway#GO:0097190;regulation of response to stimulus#GO:0048583;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8029095|UniProtKB=A0ACM8EDA8 A0ACM8EDA8 betaggt-I PTHR11774:SF4 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-1 SUBUNIT BETA catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120839368|UniProtKB=A0ACM8EMD6 A0ACM8EMD6 LOC120839368 PTHR11093:SF6 RUVB-RELATED REPTIN AND PONTIN RUVB-LIKE 1 ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545 cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;cellular component biogenesis#GO:0044085;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8043157|UniProtKB=A0ACM8EBS5 A0ACM8EBS5 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8052085|UniProtKB=A0ACM8FAF5 A0ACM8FAF5 LOC8052085 PTHR45639:SF38 HSC70CB, ISOFORM G-RELATED HEAT SHOCK 70 KDA PROTEIN 14 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 IXOSC|EnsemblGenome=LOC120838000|UniProtKB=A0ACM8EIC3 A0ACM8EIC3 LOC120838000 PTHR11645:SF0 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281 metabolite interconversion enzyme#PC00262;reductase#PC00198 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 IXOSC|EnsemblGenome=LOC8051711|UniProtKB=A0ACM8DLA4 A0ACM8DLA4 LOC8051711 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115315811|UniProtKB=A0ACM8DVB6 A0ACM8DVB6 LOC115315811 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8039894|UniProtKB=A0ACM8E6E1 A0ACM8E6E1 LOC8039894 PTHR22763:SF191 RING ZINC FINGER PROTEIN RING FINGER PROTEIN 145 HOMOLOG catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8024614|UniProtKB=A0ACM8EYS1 A0ACM8EYS1 Rme-8 PTHR36983:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 DNAJ HOMOLOG SUBFAMILY C MEMBER 13 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 vesicle-mediated transport#GO:0016192;endocytosis#GO:0006897;cellular process#GO:0009987;receptor-mediated endocytosis#GO:0006898;import into cell#GO:0098657;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120836372|UniProtKB=A0ACM8FS90 A0ACM8FS90 LOC120836372 PTHR45715:SF23 ATPASE H+-TRANSPORTING V1 SUBUNIT E1A-RELATED ATPASE H+ TRANSPORTING V1 SUBUNIT E1 ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 monoatomic ion transport#GO:0006811;proton transmembrane transport#GO:1902600;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987 proton-transporting two-sector ATPase complex#GO:0016469;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting V-type ATPase complex#GO:0033176;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;protein-containing complex#GO:0032991;vacuole#GO:0005773;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;vacuolar proton-transporting V-type ATPase complex#GO:0016471;ATPase complex#GO:1904949;transmembrane transporter complex#GO:1902495;membrane-bounded organelle#GO:0043227;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115312227|UniProtKB=A0ACM8DRN3 A0ACM8DRN3 LOC115312227 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120841200|UniProtKB=A0ACM8G283 A0ACM8G283 LOC120841200 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8039498|UniProtKB=A0ACM8EXZ5 A0ACM8EXZ5 LOC8039498 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8041595|UniProtKB=A0ACM8DKQ9 A0ACM8DKQ9 LOC8041595 PTHR12768:SF4 BECLIN 1 BECLIN-1 binding#GO:0005488;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;phosphatidylinositol 3-kinase binding#GO:0043548;protein binding#GO:0005515 response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;organelle assembly#GO:0070925;localization#GO:0051179;vacuole organization#GO:0007033;response to nutrient levels#GO:0031667;macroautophagy#GO:0016236;cellular response to starvation#GO:0009267;intracellular transport#GO:0046907;autophagy of mitochondrion#GO:0000422;cellular response to nutrient levels#GO:0031669;vacuolar transport#GO:0007034;transport#GO:0006810;mitophagy#GO:0000423;establishment of localization#GO:0051234;cellular component organization#GO:0016043;response to stimulus#GO:0050896;late endosome to vacuole transport#GO:0045324;cellular response to stress#GO:0033554;cellular localization#GO:0051641;process utilizing autophagic mechanism#GO:0061919;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;membrane protein complex#GO:0098796;extrinsic component of membrane#GO:0019898;intracellular anatomical structure#GO:0005622;transferase complex, transferring phosphorus-containing groups#GO:0061695;phosphatidylinositol 3-kinase complex, class III#GO:0035032;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;catalytic complex#GO:1902494 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115316876|UniProtKB=A0ACM8DX44 A0ACM8DX44 LOC115316876 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115311128|UniProtKB=A0ACM8FJ53 A0ACM8FJ53 LOC115311128 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121047734|UniProtKB=A0ACM8FGN4 A0ACM8FGN4 LOC121047734 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115331967|UniProtKB=A0ACM8EE13 A0ACM8EE13 LOC115331967 PTHR11929:SF194 ALPHA- 1,3 -FUCOSYLTRANSFERASE GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 3 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120850679|UniProtKB=A0ACM8FAL6 A0ACM8FAL6 LOC120850679 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313254|UniProtKB=A0ACM8G8T5 A0ACM8G8T5 LOC115313254 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837110|UniProtKB=A0ACM8EHA1 A0ACM8EHA1 LOC120837110 PTHR46289:SF21 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028242|UniProtKB=A0ACM8DWW3 A0ACM8DWW3 LOC8028242 PTHR24416:SF317 TYROSINE-PROTEIN KINASE RECEPTOR MUSCLE, SKELETAL RECEPTOR TYROSINE-PROTEIN KINASE transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;Wnt-protein binding#GO:0017147;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169 signaling receptor complex#GO:0043235;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115316895|UniProtKB=A0ACM8G0B7 A0ACM8G0B7 LOC115316895 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8023737|UniProtKB=A0ACM8DTU5 A0ACM8DTU5 LOC8023737 PTHR11021:SF1 SMALL NUCLEAR RIBONUCLEOPROTEIN F SNRNP-F U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM6 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribosome biogenesis#GO:0042254;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA splicing#GO:0008380;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 P-body#GO:0000932;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;spliceosomal tri-snRNP complex#GO:0097526;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;cytoplasmic ribonucleoprotein granule#GO:0036464;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U6 snRNP#GO:0005688;membraneless organelle#GO:0043228;Sm-like protein family complex#GO:0120114;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;U4/U6 x U5 tri-snRNP complex#GO:0046540;ribonucleoprotein granule#GO:0035770;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120848687|UniProtKB=A0ACM8FLW6 A0ACM8FLW6 LOC120848687 PTHR10816:SF15 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120843399|UniProtKB=A0ACM8FW27 A0ACM8FW27 LOC120843399 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115324203|UniProtKB=A0ACM8E3N5 A0ACM8E3N5 LOC115324203 PTHR47679:SF3 PROTEIN TORNADO 1 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8044032|UniProtKB=A0ACM8ED97 A0ACM8ED97 LOC8044032 PTHR14523:SF1 UNCHARACTERIZED PROTEIN C17ORF53 HOMOLOG HOMOLOGOUS RECOMBINATION OB-FOLD PROTEIN IXOSC|EnsemblGenome=LOC120842396|UniProtKB=A0ACM8ETN5 A0ACM8ETN5 LOC120842396 PTHR47501:SF5 TRANSPOSASE-RELATED BED-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115321314|UniProtKB=A0ACM8EUF4 A0ACM8EUF4 LOC115321314 PTHR19300:SF66 BETA-1,4-GALACTOSYLTRANSFERASE BETA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE A transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121834654|UniProtKB=A0ACM8FQX6 A0ACM8FQX6 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120839275|UniProtKB=A0ACM8G031 A0ACM8G031 LOC120839275 PTHR23140:SF4 RNA PROCESSING PROTEIN LD23810P INSULATOR SU(HW) MRNA ADAPTOR, ISOFORM B nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC121833460|UniProtKB=A0ACM8FJV6 A0ACM8FJV6 LOC121833460 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115316193|UniProtKB=A0ACM8DWA8 A0ACM8DWA8 LOC115316193 PTHR13710:SF166 DNA HELICASE RECQ FAMILY MEMBER BIFUNCTIONAL 3'-5' EXONUCLEASE_ATP-DEPENDENT HELICASE WRN ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545 cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;double-strand break repair#GO:0006302;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;telomere organization#GO:0032200;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260 membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165 DNA helicase#PC00011;DNA metabolism protein#PC00009 p53 pathway#P00059>WRN#P04617 IXOSC|EnsemblGenome=LOC115310998|UniProtKB=A0ACM8ERY6 A0ACM8ERY6 LOC115310998 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323724|UniProtKB=A0ACM8E372 A0ACM8E372 LOC115323724 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;cellular process#GO:0009987 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8053453|UniProtKB=A0ACM8DT75 A0ACM8DT75 LOC8053453 PTHR24320:SF285 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 14 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120838730|UniProtKB=A0ACM8EL59 A0ACM8EL59 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC115319644|UniProtKB=A0ACM8F3K7 A0ACM8F3K7 LOC115319644 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833028|UniProtKB=A0ACM8FIY2 A0ACM8FIY2 LOC121833028 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8039950|UniProtKB=A0ACM8DYI9 A0ACM8DYI9 LOC8039950 PTHR13398:SF0 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 GDP-FUCOSE PROTEIN O-FUCOSYLTRANSFERASE 2 fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;catalytic activity, acting on a protein#GO:0140096 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8040329|UniProtKB=A0ACM8DVC8 A0ACM8DVC8 LOC8040329 PTHR11447:SF16 CELLULAR TUMOR ANTIGEN P53 P53, ISOFORM B RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;response to stress#GO:0006950;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;regulation of apoptotic process#GO:0042981;positive regulation of transcription by RNA polymerase II#GO:0045944;signaling#GO:0023052;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;intrinsic apoptotic signaling pathway#GO:0097193;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;cellular response to stress#GO:0033554;signal transduction by p53 class mediator#GO:0072331;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator#GO:0042771;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891 chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 P53-like transcription factor#PC00253;gene-specific transcriptional regulator#PC00264 Huntington disease#P00029>p53#P00797 IXOSC|EnsemblGenome=LOC115321125|UniProtKB=A0ACM8E0Y0 A0ACM8E0Y0 LOC115321125 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847009|UniProtKB=A0ACM8FPE8 A0ACM8FPE8 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834693|UniProtKB=A0ACM8FQQ1 A0ACM8FQQ1 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835947|UniProtKB=A0ACM8FWH5 A0ACM8FWH5 LOC121835947 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121833284|UniProtKB=A0ACM8FK62 A0ACM8FK62 LOC121833284 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8034227|UniProtKB=A0ACM8E7X5 A0ACM8E7X5 LOC8034227 PTHR12442:SF22 DYNEIN INTERMEDIATE CHAIN CYTOPLASMIC DYNEIN 1 INTERMEDIATE CHAIN-RELATED protein binding#GO:0005515;binding#GO:0005488 microtubule-based process#GO:0007017;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;microtubule-based transport#GO:0099111;intracellular transport#GO:0046907;microtubule-based movement#GO:0007018;cytoskeleton-dependent intracellular transport#GO:0030705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 IXOSC|EnsemblGenome=LOC8023716|UniProtKB=A0ACM8DZP7 A0ACM8DZP7 LOC8023716 PTHR45949:SF2 SORTING NEXIN-4 SORTING NEXIN-4 transport#GO:0006810;autophagy of mitochondrion#GO:0000422;intracellular transport#GO:0046907;metabolic process#GO:0008152;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;mitophagy#GO:0000423;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;establishment of localization in cell#GO:0051649;reticulophagy#GO:0061709;macromolecule localization#GO:0033036;macroautophagy#GO:0016236;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;process utilizing autophagic mechanism#GO:0061919;protein transport#GO:0015031;cellular localization#GO:0051641;localization#GO:0051179;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;endocytic recycling#GO:0032456 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;phagophore assembly site#GO:0000407;intracellular organelle#GO:0043229;endosome#GO:0005768;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8050520|UniProtKB=A0ACM8E8V0 A0ACM8E8V0 LOC8050520 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120838565|UniProtKB=A0ACM8EJI9 A0ACM8EJI9 LOC120838565 PTHR24322:SF755 PKSB RETINOL DEHYDROGENASE 10 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC115327340|UniProtKB=A0ACM8E7X4 A0ACM8E7X4 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152 glycosidase#PC00110;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115328748|UniProtKB=A0ACM8E8L5 A0ACM8E8L5 LOC115328748 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8038441|UniProtKB=A0ACM8FX24 A0ACM8FX24 LOC8038441 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;steroid hydroxylase activity#GO:0008395;binding#GO:0005488 steroid metabolic process#GO:0008202;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8026687|UniProtKB=A0ACM8ECB2 A0ACM8ECB2 LOC8026687 PTHR11804:SF86 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED LD37516P hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC121833312|UniProtKB=A0ACM8FKF5 A0ACM8FKF5 LOC121833312 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115327237|UniProtKB=A0ACM8F9Z7 A0ACM8F9Z7 LOC115327237 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC chromatin binding#GO:0003682;binding#GO:0005488 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 transferase complex#GO:1990234;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8031167|UniProtKB=A0ACM8G2D3 A0ACM8G2D3 LOC8031167 PTHR23206:SF8 MASK PROTEIN ANKYRIN REPEAT AND KH DOMAIN-CONTAINING PROTEIN 1 ISOFORM X1 defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;immune system process#GO:0002376;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC121048564|UniProtKB=A0ACM8FIP4 A0ACM8FIP4 LOC121048564 PTHR37558:SF1 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN TRICHOHYALIN IXOSC|EnsemblGenome=LOC115329911|UniProtKB=A0ACM8FCB1 A0ACM8FCB1 LOC115329911 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8027647|UniProtKB=A0ACM8DJ89 A0ACM8DJ89 LOC8027647 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 IXOSC|EnsemblGenome=LOC8029128|UniProtKB=A0ACM8EIF6 A0ACM8EIF6 LOC8029128 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8051121|UniProtKB=A0ACM8EB41 A0ACM8EB41 LOC8051121 PTHR12560:SF0 LONGEVITY ASSURANCE FACTOR 1 LAG1 LD18904P transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;ceramide metabolic process#GO:0006672 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115321102|UniProtKB=A0ACM8EH23 A0ACM8EH23 LOC115321102 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 IXOSC|EnsemblGenome=LOC120845820|UniProtKB=A0ACM8FH08 A0ACM8FH08 LOC120845820 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8028777|UniProtKB=A0ACM8E702 A0ACM8E702 LOC8028777 PTHR36170:SF1 CENTROSOMAL PROTEIN OF 89 KDA CENTROSOMAL PROTEIN OF 89 KDA mitochondrion organization#GO:0007005;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;ciliary transition fiber#GO:0097539;microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121836050|UniProtKB=A0ACM8FWZ4 A0ACM8FWZ4 LOC121836050 PTHR21184:SF6 MENORIN (DENDRITIC BRANCHING PROTEIN) MENORIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115332473|UniProtKB=A0ACM8EDI5 A0ACM8EDI5 LOC115332473 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847632|UniProtKB=A0ACM8FYS7 A0ACM8FYS7 LOC120847632 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838419|UniProtKB=A0ACM8EKK4 A0ACM8EKK4 LOC120838419 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323065|UniProtKB=A0ACM8ENX8 A0ACM8ENX8 LOC115323065 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029601|UniProtKB=A0ACM8DVF0 A0ACM8DVF0 bor PTHR23075:SF0 PUTATIVE ATP-ASE ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3A mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120843974|UniProtKB=A0ACM8EYF4 A0ACM8EYF4 LOC120843974 PTHR43615:SF1 PHOSPHOENOLPYRUVATE SYNTHASE-RELATED PHOSPHOENOLPYRUVATE SYNTHASE IXOSC|EnsemblGenome=LOC121834491|UniProtKB=A0ACM8FNT6 A0ACM8FNT6 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8051195|UniProtKB=A0ACM8DLY7 A0ACM8DLY7 ND-B15 PTHR15469:SF0 NADH-UBIQUINONE OXIDOREDUCTASE B15 SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 4 catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8037141|UniProtKB=A0ACM8E1Y0 A0ACM8E1Y0 LOC8037141 PTHR13112:SF0 UPF3 REGULATOR OF NONSENSE TRANSCRIPTS-LIKE PROTEIN FI21285P1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of translation#GO:0045727;positive regulation of biosynthetic process#GO:0009891;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;positive regulation of protein metabolic process#GO:0051247;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120846116|UniProtKB=A0ACM8F0W2 A0ACM8F0W2 LOC120846116 PTHR11845:SF13 5'-DEOXYNUCLEOTIDASE HDDC2 5'-DEOXYNUCLEOTIDASE HDDC2 hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;5'-nucleotidase activity#GO:0008253;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115323847|UniProtKB=A0ACM8G4F2 A0ACM8G4F2 LOC115323847 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC120847951|UniProtKB=A0ACM8F4X6 A0ACM8F4X6 LOC120847951 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320376|UniProtKB=A0ACM8E0Q3 A0ACM8E0Q3 LOC115320376 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8034193|UniProtKB=A0ACM8EPU7 A0ACM8EPU7 LOC8034193 PTHR24006:SF943 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE PUF hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115308426|UniProtKB=A0ACM8DMF2 A0ACM8DMF2 RpL23 PTHR11761:SF8 50S/60S RIBOSOMAL PROTEIN L14/L23 LARGE RIBOSOMAL SUBUNIT PROTEIN UL14 rRNA binding#GO:0019843;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;RNA binding#GO:0003723;structural molecule activity#GO:0005198 cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8025601|UniProtKB=A0ACM8G5C9 A0ACM8G5C9 Ppat-Dpck PTHR10695:SF62 DEPHOSPHO-COA KINASE-RELATED CYTIDYLTRANSFERASE-LIKE DOMAIN-CONTAINING PROTEIN phosphotransferase activity, alcohol group as acceptor#GO:0016773;adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793 metabolite interconversion enzyme#PC00262;kinase#PC00137 IXOSC|EnsemblGenome=LOC120842414|UniProtKB=A0ACM8FRI6 A0ACM8FRI6 LOC120842414 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121046964|UniProtKB=A0ACM8FFD5 A0ACM8FFD5 PTHR11920:SF462 GUANYLYL CYCLASE GUANYLATE CYCLASE peptide receptor activity#GO:0001653;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;lyase activity#GO:0016829;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cyclic nucleotide biosynthetic process#GO:0009190;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cell communication#GO:0007154;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanylate cyclase#PC00114;lyase#PC00144 IXOSC|EnsemblGenome=LOC115325446|UniProtKB=A0ACM8ER83 A0ACM8ER83 LOC115325446 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121048460|UniProtKB=A0ACM8FIF7 A0ACM8FIF7 LOC121048460 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8042460|UniProtKB=A0ACM8DZ61 A0ACM8DZ61 Hrd3 PTHR11102:SF147 SEL-1-LIKE PROTEIN PROTEIN SEL-1 HOMOLOG 1 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8050684|UniProtKB=A0ACM8FXF4 A0ACM8FXF4 LOC8050684 PTHR11532:SF96 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D-LIKE PROTEIN metallopeptidase activity#GO:0008237;carboxypeptidase activity#GO:0004180;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 IXOSC|EnsemblGenome=LOC120840591|UniProtKB=A0ACM8EPT2 A0ACM8EPT2 LOC120840591 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121836496|UniProtKB=A0ACM8G072 A0ACM8G072 LOC121836496 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040338|UniProtKB=A0ACM8DKL1 A0ACM8DKL1 Pdss2 PTHR12001:SF55 GERANYLGERANYL PYROPHOSPHATE SYNTHASE ALL TRANS-POLYPRENYL-DIPHOSPHATE SYNTHASE PDSS2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987;primary metabolic process#GO:0044238;ketone metabolic process#GO:0042180;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;isoprenoid biosynthetic process#GO:0008299;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;isoprenoid metabolic process#GO:0006720 mitochondrion#GO:0005739;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033216|UniProtKB=A0ACM8EAS7 A0ACM8EAS7 LOC8033216 PTHR18874:SF10 CMF/LEK/CENP CELL DIVISION-RELATED CENTROMERE PROTEIN F IXOSC|EnsemblGenome=LOC121045780|UniProtKB=A0ACM8FM81 A0ACM8FM81 LOC121045780 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041093|UniProtKB=A0ACM8E160 A0ACM8E160 Rack1 PTHR19868:SF0 RECEPTOR FOR ACTIVATED PROTEIN KINASE C RACK1 SMALL RIBOSOMAL SUBUNIT PROTEIN RACK1 binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;translation#GO:0006412;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;metabolic process#GO:0008152;translational elongation#GO:0006414;cellular component organization or biogenesis#GO:0071840;regulation of protein metabolic process#GO:0051246;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular process#GO:0009987;gene expression#GO:0010467;negative regulation of translation#GO:0017148;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;rescue of stalled cytosolic ribosome#GO:0072344;regulation of biological process#GO:0050789;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;negative regulation of metabolic process#GO:0009892 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC121833395|UniProtKB=A0ACM8FKH1 A0ACM8FKH1 LOC121833395 PTHR13742:SF17 RETINOBLASTOMA-ASSOCIATED PROTEIN RB -RELATED RE32990P-RELATED double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of cell cycle#GO:0045786;cellular developmental process#GO:0048869;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;negative regulation of cell cycle process#GO:0010948;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;regulation of G1/S transition of mitotic cell cycle#GO:2000045;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of cell cycle G1/S phase transition#GO:1902806;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of biological process#GO:0050789 transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115317376|UniProtKB=A0ACM8G2P4 A0ACM8G2P4 LOC115317376 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115320119|UniProtKB=A0ACM8ESY5 A0ACM8ESY5 LOC115320119 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120841117|UniProtKB=A0ACM8EQK0 A0ACM8EQK0 LOC120841117 PTHR22930:SF269 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115312632|UniProtKB=A0ACM8DSD7 A0ACM8DSD7 LOC115312632 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121834815|UniProtKB=A0ACM8FRQ4 A0ACM8FRQ4 LOC121834815 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052797|UniProtKB=A0ACM8FWI9 A0ACM8FWI9 LOC8052797 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8051927|UniProtKB=A0ACM8E714 A0ACM8E714 LOC8051927 PTHR22894:SF5 RING-TYPE DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE RNF170 IXOSC|EnsemblGenome=LOC115333087|UniProtKB=A0ACM8EE23 A0ACM8EE23 LOC115333087 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 transferase#PC00220 IXOSC|EnsemblGenome=LOC115324821|UniProtKB=A0ACM8E585 A0ACM8E585 LOC115324821 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8028527|UniProtKB=A0ACM8EF03 A0ACM8EF03 PTHR31937:SF3 TRANSMEMBRANE PROTEIN 163 CONSERVED INTEGRAL MEMBRANE PROTEIN-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120848337|UniProtKB=A0ACM8F6L0 A0ACM8F6L0 LOC120848337 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331832|UniProtKB=A0ACM8ED11 A0ACM8ED11 LOC115331832 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121833930|UniProtKB=A0ACM8FMA3 A0ACM8FMA3 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8031204|UniProtKB=A0ACM8F0J1 A0ACM8F0J1 LOC8031204 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120846318|UniProtKB=A0ACM8F1B3 A0ACM8F1B3 LOC120846318 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027653|UniProtKB=A0ACM8E8V3 A0ACM8E8V3 LOC8027653 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120845451|UniProtKB=A0ACM8F1N4 A0ACM8F1N4 LOC120846441 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8039967|UniProtKB=A0ACM8ETL8 A0ACM8ETL8 LOC8039967 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC120844198|UniProtKB=A0ACM8EY24 A0ACM8EY24 LOC120844198 PTHR34072:SF52 ENZYMATIC POLYPROTEIN-RELATED REVERSE TRANSCRIPTASE_RETROTRANSPOSON-DERIVED PROTEIN RNASE H-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051938|UniProtKB=A0ACM8DYX6 A0ACM8DYX6 LOC8051938 PTHR11671:SF5 V-TYPE ATP SYNTHASE SUBUNIT D V-TYPE PROTON ATPASE SUBUNIT D primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;proton transmembrane transporter activity#GO:0015078;monoatomic cation transmembrane transporter activity#GO:0008324;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657 monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;biological regulation#GO:0065007;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;cellular homeostasis#GO:0019725;regulation of biological quality#GO:0065008;intracellular chemical homeostasis#GO:0055082;vacuolar acidification#GO:0007035 cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;membrane#GO:0016020;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;proton-transporting two-sector ATPase complex#GO:0016469;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;proton-transporting V-type ATPase complex#GO:0033176;vacuolar membrane#GO:0005774;transporter complex#GO:1990351 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC8029865|UniProtKB=A0ACM8FA65 A0ACM8FA65 LOC8029865 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120846345|UniProtKB=A0ACM8F247 A0ACM8F247 Bdp1 PTHR22929:SF0 RNA POLYMERASE III TRANSCRIPTION INITIATION FACTOR B TRANSCRIPTION FACTOR TFIIIB COMPONENT B'' HOMOLOG RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC115327885|UniProtKB=A0ACM8F468 A0ACM8F468 LOC120847515 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8027768|UniProtKB=A0ACM8DJD3 A0ACM8DJD3 LOC8027768 PTHR15069:SF1 PROTEASOME ASSEMBLY CHAPERONE 1 PROTEASOME ASSEMBLY CHAPERONE 1 binding#GO:0005488;protein-containing complex binding#GO:0044877 chaperone-mediated protein complex assembly#GO:0051131;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;protein folding chaperone complex#GO:0101031;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;nucleus#GO:0005634;cytosol#GO:0005829 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8032121|UniProtKB=A0ACM8DSU3 A0ACM8DSU3 LOC8032121 PTHR43038:SF3 ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 ABC TRANSPORTER G FAMILY MEMBER 23 ISOFORM X1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8026766|UniProtKB=A0ACM8DQZ4 A0ACM8DQZ4 LOC8026766 PTHR19849:SF1 PHOSPHOLIPASE A-2-ACTIVATING PROTEIN F-BOX_WD REPEAT-CONTAINING PROTEIN 7 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 macroautophagy#GO:0016236;proteasomal protein catabolic process#GO:0010498;autophagy#GO:0006914;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Sel 10#P01102;Parkinson disease#P00049>hSel10#P01240 IXOSC|EnsemblGenome=LOC8028552|UniProtKB=A0ACM8FBD7 A0ACM8FBD7 LOC8028552 PTHR23355:SF68 RIBONUCLEASE DIS3-LIKE EXONUCLEASE 2 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC8036440|UniProtKB=A0ACM8E0K8 A0ACM8E0K8 LOC8036440 PTHR47827:SF3 AHD DOMAIN-CONTAINING PROTEIN YEATS DOMAIN-CONTAINING PROTEIN binding#GO:0005488;chromatin binding#GO:0003682 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604 intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC8025779|UniProtKB=A0ACM8DGE6 A0ACM8DGE6 LOC8025779 PTHR12411:SF992 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN O catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121836053|UniProtKB=A0ACM8FY68 A0ACM8FY68 LOC121836053 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8050710|UniProtKB=A0ACM8DTQ1 A0ACM8DTQ1 LOC8050710 PTHR22948:SF79 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115330430|UniProtKB=A0ACM8ENP9 A0ACM8ENP9 LOC115330430 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE alpha-glucosidase activity#GO:0090599;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC120844468|UniProtKB=A0ACM8FF96 A0ACM8FF96 LOC120844468 PTHR37162:SF11 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8029211|UniProtKB=A0ACM8DPD1 A0ACM8DPD1 LOC8029211 PTHR23359:SF234 NUCLEOTIDE KINASE ADENYLATE KINASE 2, MITOCHONDRIAL phosphotransferase activity, phosphate group as acceptor#GO:0016776;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824 ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside diphosphate metabolic process#GO:0009185;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine nucleoside diphosphate metabolic process#GO:0009135;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;nucleoside phosphate biosynthetic process#GO:1901293;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;nucleoside diphosphate metabolic process#GO:0009132;organophosphate biosynthetic process#GO:0090407 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 nucleotide kinase#PC00172;kinase#PC00137 De novo purine biosynthesis#P02738>Adenylate kinase#P02896 IXOSC|EnsemblGenome=LOC8027948|UniProtKB=A0ACM8EBU1 A0ACM8EBU1 LOC8027948 PTHR44080:SF1 E3 UBIQUITIN-PROTEIN LIGASE COP1 E3 UBIQUITIN-PROTEIN LIGASE COP1 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 P53 pathway feedback loops 1#P04392>Cop-1#P04540;P53 pathway feedback loops 1#P04392>Cop-1#G04683 IXOSC|EnsemblGenome=LOC8042363|UniProtKB=A0ACM8ECY2 A0ACM8ECY2 LOC8042363 PTHR11592:SF135 GLUTATHIONE PEROXIDASE GLUTATHIONE PEROXIDASE catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887;response to oxidative stress#GO:0006979;cellular response to chemical stress#GO:0062197;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to oxidative stress#GO:0034599 peroxidase#PC00180;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836714|UniProtKB=A0ACM8G005 A0ACM8G005 LOC121836714 PTHR12474:SF0 P53 REGULATED PA26 NUCLEAR PROTEIN SESTRIN SESTRIN HOMOLOG amino acid binding#GO:0016597;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;organic acid binding#GO:0043177;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;carboxylic acid binding#GO:0031406;cation binding#GO:0043169;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 regulation of autophagy#GO:0010506;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cellular response to amino acid stimulus#GO:0071230;positive regulation of macroautophagy#GO:0016239;regulation of intracellular signal transduction#GO:1902531;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;negative regulation of intracellular signal transduction#GO:1902532;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;response to stress#GO:0006950;positive regulation of autophagy#GO:0010508;regulation of TOR signaling#GO:0032006;cellular process#GO:0009987;response to acid chemical#GO:0001101;cellular response to oxygen-containing compound#GO:1901701;positive regulation of biological process#GO:0048518;cellular response to amino acid starvation#GO:0034198;response to chemical#GO:0042221;negative regulation of signal transduction#GO:0009968;negative regulation of TORC1 signaling#GO:1904262;regulation of macroautophagy#GO:0016241;response to starvation#GO:0042594;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;response to nitrogen compound#GO:1901698;regulation of metabolic process#GO:0019222;response to nutrient levels#GO:0031667;positive regulation of cellular process#GO:0048522;negative regulation of response to stimulus#GO:0048585;cellular response to nitrogen compound#GO:1901699;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267;regulation of response to stimulus#GO:0048583;cellular response to nutrient levels#GO:0031669;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of TORC1 signaling#GO:1903432 peroxidase#PC00180;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8032028|UniProtKB=A0ACM8EI18 A0ACM8EI18 LOC8032028 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115324873|UniProtKB=A0ACM8FSN7 A0ACM8FSN7 LOC115324873 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115314898|UniProtKB=A0ACM8FSU6 A0ACM8FSU6 LOC115314898 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC8034702|UniProtKB=A0ACM8DXE8 A0ACM8DXE8 LOC8034702 PTHR34094:SF1 FAMILY NOT NAMED PROTEIN FAM185A IXOSC|EnsemblGenome=LOC8042563|UniProtKB=A0ACM8DKZ3 A0ACM8DKZ3 LOC8042563 PTHR21860:SF2 TRANSCRIPTION INITIATION FACTOR IIIC TFIIIC , POLYPEPTIDE 6-RELATED GENERAL TRANSCRIPTION FACTOR 3C POLYPEPTIDE 6 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;transcription by RNA polymerase III#GO:0006383;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleic acid biosynthetic process#GO:0141187;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 transcription regulator complex#GO:0005667;transcription factor TFIIIC complex#GO:0000127;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC120844377|UniProtKB=A0ACM8FK59 A0ACM8FK59 LOC120844377 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115318489|UniProtKB=A0ACM8EFU0 A0ACM8EFU0 LOC115318489 PTHR48598:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8038726|UniProtKB=A0ACM8F6K2 A0ACM8F6K2 LOC8038726 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849772|UniProtKB=A0ACM8F8B4 A0ACM8F8B4 LOC120849772 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8029021|UniProtKB=A0ACM8EWY0 A0ACM8EWY0 LOC8029021 PTHR21483:SF18 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 RNA POLYMERASE II-ASSOCIATED PROTEIN 1 IXOSC|EnsemblGenome=LOC115321248|UniProtKB=A0ACM8EXJ1 A0ACM8EXJ1 LOC115321248 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843925|UniProtKB=A0ACM8G3J2 A0ACM8G3J2 LOC120843925 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120846577|UniProtKB=A0ACM8F3L0 A0ACM8F3L0 LOC8041146 PTHR24068:SF126 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 S acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;catabolic process#GO:0009056;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 IXOSC|EnsemblGenome=LOC8031058|UniProtKB=A0ACM8FEX6 A0ACM8FEX6 LOC8031058 PTHR24356:SF450 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TRICORNERED protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 establishment or maintenance of cell polarity#GO:0007163;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120848654|UniProtKB=A0ACM8G8H5 A0ACM8G8H5 LOC120848654 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115314449|UniProtKB=A0ACM8FKD6 A0ACM8FKD6 LOC115314449 PTHR24394:SF62 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8031379|UniProtKB=A0ACM8EN13 A0ACM8EN13 LOC8031379 PTHR16967:SF1 LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG LEYDIG CELL TUMOR 10 KDA PROTEIN HOMOLOG biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of cell population proliferation#GO:0008284 IXOSC|EnsemblGenome=LOC8029077|UniProtKB=A0ACM8DYT1 A0ACM8DYT1 LOC8029077 PTHR11377:SF5 N-MYRISTOYL TRANSFERASE GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 localization#GO:0051179;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657;localization within membrane#GO:0051668;cellular process#GO:0009987 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220 IXOSC|EnsemblGenome=LOC120844855|UniProtKB=A0ACM8EZW1 A0ACM8EZW1 LOC120844855 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 IXOSC|EnsemblGenome=LOC8023397|UniProtKB=A0ACM8DGW4 A0ACM8DGW4 LOC8023397 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8035807|UniProtKB=A0ACM8EPH0 A0ACM8EPH0 LOC8035807 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364 glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC120847014|UniProtKB=A0ACM8G5H4 A0ACM8G5H4 LOC120847014 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115323233|UniProtKB=A0ACM8E3Q8 A0ACM8E3Q8 LOC115323233 PTHR23415:SF48 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT/60S RIBOSOME SUBUNIT BIOGENESIS PROTEIN NIP7 CYCLIN-DEPENDENT KINASES REGULATORY SUBUNIT 2 kinase activator activity#GO:0019209;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;protein kinase activator activity#GO:0030295;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;protein kinase regulator activity#GO:0019887;cyclin-dependent protein kinase regulator activity#GO:0019914 cell cycle process#GO:0022402;cellular process#GO:0009987;cell cycle#GO:0007049;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770 cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;nucleus#GO:0005634;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;SCF ubiquitin ligase complex#GO:0019005;organelle#GO:0043226;cellular anatomical structure#GO:0110165;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115325061|UniProtKB=A0ACM8F1J1 A0ACM8F1J1 LOC115325061 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328222|UniProtKB=A0ACM8F1P8 A0ACM8F1P8 LOC115328222 PTHR33198:SF22 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034697|UniProtKB=A0ACM8DZQ5 A0ACM8DZQ5 LOC8034697 PTHR15036:SF85 PIKACHURIN-LIKE PROTEIN LAMININ G DOMAIN-CONTAINING PROTEIN signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120843196|UniProtKB=A0ACM8EWL5 A0ACM8EWL5 LOC120843196 PTHR11562:SF17 CATION EFFLUX PROTEIN/ ZINC TRANSPORTER LD05335P transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;transport#GO:0006810;transition metal ion transport#GO:0000041;zinc ion transmembrane transport#GO:0071577 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115310068|UniProtKB=A0ACM8FEL4 A0ACM8FEL4 LOC115310068 PTHR24346:SF51 MAP/MICROTUBULE AFFINITY-REGULATING KINASE PAS DOMAIN-CONTAINING SERINE_THREONINE-PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 signaling#GO:0023052;regulation of carbohydrate biosynthetic process#GO:0043255;negative regulation of metabolic process#GO:0009892;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of polysaccharide metabolic process#GO:0032881;signal transduction#GO:0007165;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of biosynthetic process#GO:0009889;regulation of glycogen biosynthetic process#GO:0005979;negative regulation of cellular process#GO:0048523;regulation of carbohydrate metabolic process#GO:0006109 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8040669|UniProtKB=A0ACM8DH13 A0ACM8DH13 LOC8040669 PTHR11839:SF1 UDP/ADP-SUGAR PYROPHOSPHATASE ADP-SUGAR PYROPHOSPHATASE hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;pyrophosphatase#PC00196 IXOSC|EnsemblGenome=LOC115309194|UniProtKB=A0ACM8EQX4 A0ACM8EQX4 LOC115309194 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115323589|UniProtKB=A0ACM8ELN6 A0ACM8ELN6 LOC115323589 PTHR10336:SF196 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN PHOSPHOINOSITIDE PHOSPHOLIPASE C lipase activity#GO:0016298;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of cell communication#GO:0010646;signaling#GO:0023052;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;cell-cell signaling#GO:0007267;cellular process#GO:0009987;regulation of biological process#GO:0050789;cell communication#GO:0007154;regulation of signaling#GO:0023051 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;lipase#PC00143 5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581 IXOSC|EnsemblGenome=LOC115316681|UniProtKB=A0ACM8ELW8 A0ACM8ELW8 LOC115316681 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8053156|UniProtKB=A0ACM8DXA6 A0ACM8DXA6 LOC8053156 PTHR46144:SF6 ZINC FINGER PROTEIN 385B-LIKE U1-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038777|UniProtKB=A0ACM8DK85 A0ACM8DK85 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121046457|UniProtKB=A0ACM8FZL0 A0ACM8FZL0 LOC121046457 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8051043|UniProtKB=A0ACM8ECL8 A0ACM8ECL8 LOC8051043 PTHR11309:SF47 FRIZZLED FRIZZLED signaling receptor activity#GO:0038023;Wnt-protein binding#GO:0017147;molecular transducer activity#GO:0060089;protein binding#GO:0005515;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488 cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;cell surface receptor signaling pathway#GO:0007166;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;non-canonical Wnt signaling pathway#GO:0035567 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 Wnt signaling pathway#P00057>Frizzled#P01428;Alzheimer disease-presenilin pathway#P00004>Frizzled#P00119;Angiogenesis#P00005>Fzd#P00189;Cadherin signaling pathway#P00012>Frizzled#P00475 IXOSC|EnsemblGenome=LOC8023653|UniProtKB=A0ACM8E5P5 A0ACM8E5P5 LOC8023653 PTHR45695:SF38 LEUCOKININ RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 83 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120851109|UniProtKB=A0ACM8FBA4 A0ACM8FBA4 LOC120851109 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8023438|UniProtKB=A0ACM8DH22 A0ACM8DH22 Hsc70Cb PTHR45639:SF4 HSC70CB, ISOFORM G-RELATED HSC70CB, ISOFORM G nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 Hsp70 family chaperone#PC00027;chaperone#PC00072 IXOSC|EnsemblGenome=LOC115311396|UniProtKB=A0ACM8DQZ8 A0ACM8DQZ8 LOC115311396 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120850176|UniProtKB=A0ACM8F9H0 A0ACM8F9H0 LOC120850176 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8025469|UniProtKB=A0ACM8DTK7 A0ACM8DTK7 Uch-L5 PTHR10589:SF51 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE ISOZYME L5 catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005 regulation of chromosome organization#GO:0033044;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8039226|UniProtKB=A0ACM8EYL4 A0ACM8EYL4 LOC8039226 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC-RELATED protein binding#GO:0005515;binding#GO:0005488 microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;dynein complex#GO:0030286;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 IXOSC|EnsemblGenome=LOC115326092|UniProtKB=A0ACM8F3E5 A0ACM8F3E5 LOC115326092 PTHR15627:SF14 NATURAL KILLER CELL-SPECIFIC ANTIGEN KLIP1 PROTEIN YIPF3 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121832879|UniProtKB=A0ACM8G8V2 A0ACM8G8V2 LOC121832879 PTHR11959:SF16 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE 4-HYDROXYPHENYLPYRUVATE DIOXYGENASE dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;catalytic activity#GO:0003824 carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8040630|UniProtKB=A0ACM8DXQ9 A0ACM8DXQ9 LOC8040630 PTHR24241:SF83 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G PROTEIN-COUPLED RECEPTOR 150-RELATED G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120842041|UniProtKB=A0ACM8EU18 A0ACM8EU18 LOC120842041 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115324097|UniProtKB=A0ACM8ELM2 A0ACM8ELM2 LOC115324097 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8037354|UniProtKB=A0ACM8E7N8 A0ACM8E7N8 LOC8037354 PTHR46184:SF5 UNCONVENTIONAL MYOSIN-IXB-LIKE PROTEIN UNCONVENTIONAL MYOSIN-IXA-LIKE catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal protein binding#GO:0008092;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;binding#GO:0005488;actin binding#GO:0003779;ATP-dependent activity#GO:0140657;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;actin cytoskeleton#GO:0015629 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC115327260|UniProtKB=A0ACM8G2H0 A0ACM8G2H0 LOC115327260 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121836506|UniProtKB=A0ACM8FZV8 A0ACM8FZV8 LOC121836506 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318467|UniProtKB=A0ACM8FKR1 A0ACM8FKR1 LOC115318467 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8041373|UniProtKB=A0ACM8DRI4 A0ACM8DRI4 LOC8041373 PTHR12708:SF0 DNA POLYMERASE EPSILON SUBUNIT B DNA POLYMERASE EPSILON SUBUNIT 2 nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;DNA synthesis involved in DNA replication#GO:0090592;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;translesion synthesis#GO:0019985 chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;epsilon DNA polymerase complex#GO:0008622;membraneless organelle#GO:0043228 DNA-directed DNA polymerase#PC00018 IXOSC|EnsemblGenome=LOC120849119|UniProtKB=A0ACM8F671 A0ACM8F671 LOC120849119 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840872|UniProtKB=A0ACM8EQN1 A0ACM8EQN1 LOC120840872 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848795|UniProtKB=A0ACM8F6D6 A0ACM8F6D6 LOC120848795 PTHR47160:SF11 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040878|UniProtKB=A0ACM8FLV1 A0ACM8FLV1 LOC8040878 PTHR11707:SF28 L-ASPARAGINASE 60 KDA LYSOPHOSPHOLIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;amidase activity#GO:0004040;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8041672|UniProtKB=A0ACM8DKS1 A0ACM8DKS1 LOC8041672 PTHR31809:SF0 BUD13 HOMOLOG BUD13 HOMOLOG cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115321948|UniProtKB=A0ACM8E1I5 A0ACM8E1I5 LOC115321948 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115314025|UniProtKB=A0ACM8ER06 A0ACM8ER06 LOC115314025 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;enzyme regulator activity#GO:0030234 cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC115323838|UniProtKB=A0ACM8E3D5 A0ACM8E3D5 LOC115323838 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8043260|UniProtKB=A0ACM8E8Z6 A0ACM8E8Z6 LOC8043260 PTHR24014:SF6 2-OXOGLUTARATE AND IRON-DEPENDENT OXYGENASE DOMAIN-CONTAINING PROTEIN 2 PENTATRICOPEPTIDE REPEAT-CONTAINING PROTEIN 1, MITOCHONDRIAL binding#GO:0005488;nucleic acid binding#GO:0003676;tRNA binding#GO:0000049;RNA binding#GO:0003723 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;RNA 3'-end processing#GO:0031123;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;tRNA 3'-end processing#GO:0042780;mitochondrial RNA modification#GO:1900864;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8032441|UniProtKB=A0ACM8F9W8 A0ACM8F9W8 Csl4 PTHR12686:SF8 3'-5' EXORIBONUCLEASE CSL4-RELATED EXOSOME COMPLEX COMPONENT CSL4 ribosome biogenesis#GO:0042254;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of gene expression#GO:0010629;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;maturation of 5.8S rRNA#GO:0000460;mRNA metabolic process#GO:0016071;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;RNA 3'-end processing#GO:0031123;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA biosynthetic process#GO:0032774;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA metabolism protein#PC00031;exoribonuclease#PC00099 IXOSC|EnsemblGenome=LOC120842394|UniProtKB=A0ACM8ETG1 A0ACM8ETG1 LOC120842394 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8033891|UniProtKB=A0ACM8DW74 A0ACM8DW74 LOC8033891 PTHR43975:SF6 ZGC:101858 EG:BACR7A4.14 PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115312041|UniProtKB=A0ACM8DRI2 A0ACM8DRI2 LOC115312041 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;monoatomic cation channel activity#GO:0005261;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;localization#GO:0051179;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, cholinergic#GO:0007271;transport#GO:0006810;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC121836189|UniProtKB=A0ACM8FYR8 A0ACM8FYR8 LOC121836189 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115312451|UniProtKB=A0ACM8G333 A0ACM8G333 LOC115312451 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8052709|UniProtKB=A0ACM8DGJ9 A0ACM8DGJ9 LOC8052709 PTHR31800:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030 IXOSC|EnsemblGenome=LOC121048063|UniProtKB=A0ACM8FG63 A0ACM8FG63 LOC121048063 PTHR39069:SF11 ECDYSONE-INDUCIBLE GENE E1, ISOFORM A EB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321319|UniProtKB=A0ACM8E1U4 A0ACM8E1U4 LOC115321319 PTHR46880:SF5 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8054045|UniProtKB=A0ACM8DXQ5 A0ACM8DXQ5 Sps1 PTHR10256:SF0 SELENIDE, WATER DIKINASE INACTIVE SELENIDE, WATER DIKINASE-LIKE PROTEIN-RELATED transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8033400|UniProtKB=A0ACM8F8H7 A0ACM8F8H7 LOC8033400 PTHR13199:SF11 GH03947P PROTEIN ATOSSA IXOSC|EnsemblGenome=LOC8025402|UniProtKB=A0ACM8EAH1 A0ACM8EAH1 Tmx3 PTHR46426:SF2 PROTEIN DISULFIDE-ISOMERASE TMX3 LD24073P endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8030281|UniProtKB=A0ACM8DWE0 A0ACM8DWE0 Mdh1 PTHR23382:SF34 MALATE DEHYDROGENASE MALATE DEHYDROGENASE, CYTOPLASMIC oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;pyridine-containing compound metabolic process#GO:0072524;oxoacid metabolic process#GO:0043436;nucleotide metabolic process#GO:0009117;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 dehydrogenase#PC00092 TCA cycle#P00051>Malate Dehydrogenase#P01270 IXOSC|EnsemblGenome=LOC120849755|UniProtKB=A0ACM8F7B8 A0ACM8F7B8 LOC120849755 PTHR22838:SF28 WD REPEAT PROTEIN 26-RELATED WD REPEAT-CONTAINING PROTEIN 26 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC115316933|UniProtKB=A0ACM8DX58 A0ACM8DX58 LOC115316933 PTHR23510:SF16 INNER MEMBRANE TRANSPORT PROTEIN YAJR MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8036491|UniProtKB=A0ACM8DZE6 A0ACM8DZE6 Prp3 PTHR14212:SF0 U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398 intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;U4/U6 x U5 tri-snRNP complex#GO:0046540;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA splicing factor#PC00148 mRNA splicing#P00058>U6#P01473;mRNA splicing#P00058>U4#P01476 IXOSC|EnsemblGenome=LOC121833902|UniProtKB=A0ACM8FPG2 A0ACM8FPG2 PTHR11224:SF10 MAKORIN-RELATED RING-TYPE E3 UBIQUITIN TRANSFERASE catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120842143|UniProtKB=A0ACM8ET80 A0ACM8ET80 LOC120842143 PTHR11473:SF15 AROMATIC AMINO ACID HYDROXYLASE TYROSINE 3-MONOOXYGENASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 reproductive process#GO:0022414;signaling#GO:0023052;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;multicellular organismal reproductive process#GO:0048609;cell communication#GO:0007154;nervous system process#GO:0050877;cognition#GO:0050890;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;synaptic transmission, dopaminergic#GO:0001963;cellular process#GO:0009987;synaptic signaling#GO:0099536;system process#GO:0003008 neuron projection#GO:0043005;cell body#GO:0044297;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;axon#GO:0030424;intracellular anatomical structure#GO:0005622;perikaryon#GO:0043204 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 Dopamine receptor mediated signaling pathway#P05912>TH#P05970;Adrenaline and noradrenaline biosynthesis#P00001>TH#P00062 IXOSC|EnsemblGenome=LOC120841189|UniProtKB=A0ACM8ES61 A0ACM8ES61 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8025955|UniProtKB=A0ACM8E7C0 A0ACM8E7C0 LOC8025955 PTHR12274:SF3 GRANULIN GRANULIN PRECURSOR extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120836567|UniProtKB=A0ACM8EFY1 A0ACM8EFY1 LOC120836567 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324738|UniProtKB=A0ACM8E487 A0ACM8E487 LOC115324738 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115327570|UniProtKB=A0ACM8E776 A0ACM8E776 LOC115327570 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035487|UniProtKB=A0ACM8EYZ6 A0ACM8EYZ6 LOC8035487 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115309426|UniProtKB=A0ACM8F2V8 A0ACM8F2V8 LOC115309426 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8028895|UniProtKB=A0ACM8DHB8 A0ACM8DHB8 LSm7 PTHR10553:SF44 SMALL NUCLEAR RIBONUCLEOPROTEIN U6 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM7 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 protein-containing complex#GO:0032991;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U12-type spliceosomal complex#GO:0005689;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;Sm-like protein family complex#GO:0120114;U6 snRNP#GO:0005688;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;spliceosomal complex#GO:0005681;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8042092|UniProtKB=A0ACM8F8S6 A0ACM8F8S6 LOC8042092 PTHR11850:SF108 HOMEOBOX PROTEIN TRANSCRIPTION FACTORS HOMEOBOX PROTEIN EXTRADENTICLE sequence-specific double-stranded DNA binding#GO:1990837;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216 embryonic organ development#GO:0048568;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;animal organ morphogenesis#GO:0009887;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;neuron development#GO:0048666;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;cell development#GO:0048468;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;neuron differentiation#GO:0030182;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;embryo development#GO:0009790;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC120838378|UniProtKB=A0ACM8EJ39 A0ACM8EJ39 LOC120838378 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115327648|UniProtKB=A0ACM8G5U6 A0ACM8G5U6 LOC115327648 PTHR13964:SF27 RBP-RELATED HAT-TRICK, ISOFORM D sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC115319183|UniProtKB=A0ACM8DZG6 A0ACM8DZG6 LOC115319183 PTHR11601:SF62 CYSTEINE DESULFURYLASE FAMILY MEMBER SELENOCYSTEINE LYASE lyase#PC00144;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8039110|UniProtKB=A0ACM8DQ15 A0ACM8DQ15 PTHR31017:SF2 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED DENN DOMAIN-CONTAINING PROTEIN 11 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121837804|UniProtKB=A0ACM8G4V7 A0ACM8G4V7 LOC121837804 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322097|UniProtKB=A0ACM8E1Q9 A0ACM8E1Q9 PTHR43995:SF1 PRE-MRNA-PROCESSING FACTOR 19 PRE-MRNA-PROCESSING FACTOR 19 aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;cytoplasm#GO:0005737 RNA processing factor#PC00147;RNA metabolism protein#PC00031 mRNA splicing#P00058>U4#P01476 IXOSC|EnsemblGenome=LOC120846361|UniProtKB=A0ACM8F1F2 A0ACM8F1F2 LOC120846361 PTHR15092:SF50 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 POLY(A)-SPECIFIC RIBONUCLEASE PNLDC1 nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;RNA binding#GO:0003723;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540 regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulatory ncRNA-mediated gene silencing#GO:0031047;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC120847800|UniProtKB=A0ACM8G3P6 A0ACM8G3P6 LOC120847800 PTHR10751:SF144 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 heterotrimeric G-protein#PC00117;G-protein#PC00020 IXOSC|EnsemblGenome=LOC121048204|UniProtKB=A0ACM8G813 A0ACM8G813 LOC121048204 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8040935|UniProtKB=A0ACM8F6U1 A0ACM8F6U1 LOC8040935 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC115312574|UniProtKB=A0ACM8EM75 A0ACM8EM75 LOC115312574 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;peptidase activity#GO:0008233 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule catabolic process#GO:0044282;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120850599|UniProtKB=A0ACM8FB78 A0ACM8FB78 LOC120850599 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8042420|UniProtKB=A0ACM8E2H1 A0ACM8E2H1 LOC8042420 PTHR14308:SF0 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 regulation of cell growth#GO:0001558;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of growth#GO:0040008 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC115312680|UniProtKB=A0ACM8EYP1 A0ACM8EYP1 LOC115312680 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8037829|UniProtKB=A0ACM8DX64 A0ACM8DX64 LOC8037829 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8027168|UniProtKB=A0ACM8F2I2 A0ACM8F2I2 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115318259|UniProtKB=A0ACM8FTK0 A0ACM8FTK0 LOC115318259 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318736|UniProtKB=A0ACM8DY79 A0ACM8DY79 LOC115318736 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8051461|UniProtKB=A0ACM8EBK8 A0ACM8EBK8 LOC8051461 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034502|UniProtKB=A0ACM8EHN3 A0ACM8EHN3 dare PTHR11938:SF151 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE NADPH:ADRENODOXIN OXIDOREDUCTASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 steroid metabolic process#GO:0008202;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;primary metabolic process#GO:0044238;steroid biosynthetic process#GO:0006694;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>FdxR#P04604 IXOSC|EnsemblGenome=LOC121837266|UniProtKB=A0ACM8G3Z7 A0ACM8G3Z7 LOC121837266 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8037608|UniProtKB=A0ACM8EAI2 A0ACM8EAI2 Oseg2 PTHR15722:SF2 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 172 HOMOLOG organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary transport#GO:0042073;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;cilium organization#GO:0044782 ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;membraneless organelle#GO:0043228;ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intraciliary transport particle B#GO:0030992;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;axoneme#GO:0005930;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929 structural protein#PC00211 IXOSC|EnsemblGenome=LOC8036516|UniProtKB=A0ACM8DUP8 A0ACM8DUP8 LOC8036516 PTHR23152:SF38 2-OXOGLUTARATE DEHYDROGENASE 2-OXOADIPATE DEHYDROGENASE COMPLEX COMPONENT E1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;cellular process#GO:0009987 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120836181|UniProtKB=A0ACM8EG22 A0ACM8EG22 LOC120836190 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308388|UniProtKB=A0ACM8DMC5 A0ACM8DMC5 LOC115308388 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8054076|UniProtKB=A0ACM8F595 A0ACM8F595 LOC8054076 PTHR12263:SF0 VACUOLAR ATP SYNTHASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;proton transmembrane transport#GO:1902600;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773;proton-transporting two-sector ATPase complex#GO:0016469;vacuolar membrane#GO:0005774;transporter complex#GO:1990351;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;membrane protein complex#GO:0098796;cation-transporting ATPase complex#GO:0090533;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transmembrane transporter complex#GO:1902495;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 primary active transporter#PC00068;ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC121838408|UniProtKB=A0ACM8G838 A0ACM8G838 LOC121838408 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115327000|UniProtKB=A0ACM8EML2 A0ACM8EML2 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024262|UniProtKB=A0ACM8DUL7 A0ACM8DUL7 LOC8024262 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120840161|UniProtKB=A0ACM8EMT4 A0ACM8EMT4 LOC120840161 PTHR11547:SF38 ARGININE OR CREATINE KINASE ARGININE KINASE 1-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8042381|UniProtKB=A0ACM8F8B7 A0ACM8F8B7 LOC8042381 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120846217|UniProtKB=A0ACM8F1R8 A0ACM8F1R8 LOC120846217 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 nuclear body#GO:0016604;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC115324519|UniProtKB=A0ACM8F6V1 A0ACM8F6V1 LOC115324519 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120840319|UniProtKB=A0ACM8ENN2 A0ACM8ENN2 LOC120840319 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121837588|UniProtKB=A0ACM8G446 A0ACM8G446 LOC121837588 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8024682|UniProtKB=A0ACM8DVP5 A0ACM8DVP5 LOC8024682 PTHR12681:SF0 ZINC FINGER-CONTAINING PROTEIN P48ZNF ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121836478|UniProtKB=A0ACM8FYT8 A0ACM8FYT8 LOC121836478 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8037192|UniProtKB=A0ACM8DZW0 A0ACM8DZW0 LOC8037192 PTHR18939:SF4 RIBOSOME BINDING PROTEIN-1 RIBOSOME-BINDING PROTEIN 1 endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8037518|UniProtKB=A0ACM8DWM3 A0ACM8DWM3 LOC8037518 PTHR13382:SF88 MITOCHONDRIAL ATP SYNTHASE COUPLING FACTOR B F-BOX DOMAIN-CONTAINING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;cytoplasm#GO:0005737;SCF ubiquitin ligase complex#GO:0019005;cullin-RING ubiquitin ligase complex#GO:0031461;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC120848804|UniProtKB=A0ACM8F6E1 A0ACM8F6E1 LOC120848804 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120835990|UniProtKB=A0ACM8FBX7 A0ACM8FBX7 LOC120835990 PTHR31198:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 84 CENTROSOMAL AT-AC SPLICING FACTOR IXOSC|EnsemblGenome=LOC120842676|UniProtKB=A0ACM8EU91 A0ACM8EU91 LOC120842676 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838338|UniProtKB=A0ACM8G8Q9 A0ACM8G8Q9 LOC121838338 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034297|UniProtKB=A0ACM8ED76 A0ACM8ED76 LOC8034297 PTHR13763:SF0 BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1 BRCT DOMAIN-CONTAINING PROTEIN acyltransferase activity#GO:0016746;binding#GO:0005488;nucleic acid binding#GO:0003676;ubiquitin-like protein transferase activity#GO:0019787;DNA binding#GO:0003677;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;damaged DNA binding#GO:0003684;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;recombinational repair#GO:0000725;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;negative regulation of mitotic cell cycle phase transition#GO:1901991;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;regulation of biological process#GO:0050789 condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;DNA repair complex#GO:1990391;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120839236|UniProtKB=A0ACM8ELR6 A0ACM8ELR6 LOC120839236 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120837873|UniProtKB=A0ACM8EI04 A0ACM8EI04 LOC120837873 PTHR11616:SF334 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1 amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;metal ion transmembrane transporter activity#GO:0046873;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283 nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;establishment of localization#GO:0051234;import into cell#GO:0098657;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;glycine transport#GO:0015816;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8051083|UniProtKB=A0ACM8E4D3 A0ACM8E4D3 LOC8051083 PTHR48041:SF144 ABC TRANSPORTER G FAMILY MEMBER 28 LD11139P lipid transfer activity#GO:0120013;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;cholesterol transfer activity#GO:0120020;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;sterol transfer activity#GO:0120015 establishment of localization#GO:0051234;sterol transport#GO:0015918;cholesterol homeostasis#GO:0042632;chemical homeostasis#GO:0048878;transport#GO:0006810;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cholesterol transport#GO:0030301;cholesterol efflux#GO:0033344;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;organic hydroxy compound transport#GO:0015850;lipid localization#GO:0010876;homeostatic process#GO:0042592;lipid homeostasis#GO:0055088 ATP-binding cassette (ABC) transporter complex#GO:0043190;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ATPase dependent transmembrane transport complex#GO:0098533;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8035734|UniProtKB=A0ACM8DRQ4 A0ACM8DRQ4 LOC8035734 PTHR45695:SF44 LEUCOKININ RECEPTOR-RELATED SOMATOSTATIN RECEPTOR TYPE 3 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8034828|UniProtKB=A0ACM8DJK6 A0ACM8DJK6 LOC8034828 PTHR13093:SF0 ZINC FINGER HIT DOMAIN CONTAINING PROTEIN 1 ZINC FINGER HIT DOMAIN-CONTAINING PROTEIN 1 nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;chromatin binding#GO:0003682;binding#GO:0005488 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular anatomical structure#GO:0005622;INO80-type complex#GO:0097346;membrane-bounded organelle#GO:0043227;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;Swr1 complex#GO:0000812;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8038807|UniProtKB=A0ACM8ELF3 A0ACM8ELF3 LOC8038807 PTHR24241:SF117 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE S RECEPTOR-LIKE signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 response to hormone#GO:0009725;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120849426|UniProtKB=A0ACM8FKT1 A0ACM8FKT1 LOC120849426 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120850343|UniProtKB=A0ACM8FAM9 A0ACM8FAM9 LOC120850343 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115329373|UniProtKB=A0ACM8EIT0 A0ACM8EIT0 LOC115329373 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120841915|UniProtKB=A0ACM8ESS8 A0ACM8ESS8 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8034811|UniProtKB=A0ACM8DPK5 A0ACM8DPK5 LOC8034811 PTHR43176:SF38 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL deacylase activity#GO:0160215;catalytic activity#GO:0003824;fatty acyl-CoA hydrolase activity#GO:0047617;acyl-CoA hydrolase activity#GO:0016289;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;hydrolase activity#GO:0016787 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8034802|UniProtKB=A0ACM8DJJ5 A0ACM8DJJ5 LOC8034802 PTHR28607:SF4 EXPRESSED PROTEIN MEMBRANE PROTEIN FAM174-LIKE IXOSC|EnsemblGenome=LOC8035834|UniProtKB=A0ACM8EAD7 A0ACM8EAD7 LOC8035834 PTHR24223:SF470 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER SUR transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121832871|UniProtKB=A0ACM8FKY7 A0ACM8FKY7 LOC121832871 PTHR11638:SF93 ATP-DEPENDENT CLP PROTEASE MITOCHONDRIAL DISAGGREGASE hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787 response to heat#GO:0009408;cellular response to heat#GO:0034605;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8030418|UniProtKB=A0ACM8E4I2 A0ACM8E4I2 LOC8030418 PTHR21346:SF0 FUN14 DOMAIN CONTAINING RE45833P cellular process#GO:0009987;autophagy#GO:0006914;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;process utilizing autophagic mechanism#GO:0061919;catabolic process#GO:0009056 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741 IXOSC|EnsemblGenome=LOC8039752|UniProtKB=A0ACM8E7M4 A0ACM8E7M4 LOC8039752 PTHR22988:SF85 MYOTONIC DYSTROPHY S/T KINASE-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 actin cytoskeleton organization#GO:0030036;actomyosin structure organization#GO:0031032;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;actin filament-based process#GO:0030029 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8038594|UniProtKB=A0ACM8FY96 A0ACM8FY96 LOC8038594 PTHR46756:SF29 TRANSGELIN GAS2-LIKE PROTEIN PICKLED EGGS binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular process#GO:0009987;macromolecule localization#GO:0033036;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule cytoskeleton organization#GO:0070507;protein localization to microtubule cytoskeleton#GO:0072698;actin filament organization#GO:0007015;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;regulation of microtubule polymerization or depolymerization#GO:0031110;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;protein localization to cytoskeleton#GO:0044380;cellular component organization#GO:0016043;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component organization#GO:0051128;protein localization to organelle#GO:0033365;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;microtubule bundle formation#GO:0001578;actin filament-based process#GO:0030029;regulation of microtubule-based process#GO:0032886;supramolecular fiber organization#GO:0097435;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226 microtubule plus-end#GO:0035371;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;stress fiber#GO:0001725;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;microtubule cytoskeleton#GO:0015630;actomyosin#GO:0042641;microtubule#GO:0005874;actin filament bundle#GO:0032432;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;microtubule end#GO:1990752 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8038837|UniProtKB=A0ACM8E4E9 A0ACM8E4E9 LOC8038837 PTHR18952:SF283 CARBONIC ANHYDRASE CARBONIC ANHYDRASE XB-RELATED dehydratase#PC00091;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033142|UniProtKB=A0ACM8DHH6 A0ACM8DHH6 LOC8033142 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120844725|UniProtKB=A0ACM8EZK5 A0ACM8EZK5 LOC120844725 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120850528|UniProtKB=A0ACM8FAD5 A0ACM8FAD5 LOC120850528 PTHR21348:SF4 FAMILY NOT NAMED SULFIREDOXIN-1 oxidoreductase activity#GO:0016491;antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to oxidative stress#GO:0034599;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979;cellular response to stress#GO:0033554;cellular response to chemical stimulus#GO:0070887 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC115331860|UniProtKB=A0ACM8ECV6 A0ACM8ECV6 LOC115331860 PTHR24404:SF116 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8042097|UniProtKB=A0ACM8FX46 A0ACM8FX46 LOC8042097 PTHR11640:SF136 NEPHRIN NEPHRIN protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;anchoring junction#GO:0070161;plasma membrane#GO:0005886 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121833147|UniProtKB=A0ACM8FKK4 A0ACM8FKK4 LOC121833147 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8029913|UniProtKB=A0ACM8DJ35 A0ACM8DJ35 LOC8029913 PTHR12626:SF15 PROGRAMMED CELL DEATH 4 PROGRAMMED CELL DEATH PROTEIN 4 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 translation factor#PC00223 IXOSC|EnsemblGenome=LOC121834231|UniProtKB=A0ACM8FPA7 A0ACM8FPA7 PTHR23248:SF9 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 regulation of biological quality#GO:0065008;plasma membrane organization#GO:0007009;localization#GO:0051179;lipid localization#GO:0010876;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of membrane lipid distribution#GO:0097035;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;phospholipid transport#GO:0015914;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8025487|UniProtKB=A0ACM8DT00 A0ACM8DT00 LOC8025487 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8036795|UniProtKB=A0ACM8DUY1 A0ACM8DUY1 LOC8036795 PTHR21716:SF4 TRANSMEMBRANE PROTEIN TRANSMEMBRANE PROTEIN 245 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8040499|UniProtKB=A0ACM8DZA5 A0ACM8DZA5 LOC8040499 PTHR11785:SF531 AMINO ACID TRANSPORTER LARGE NEUTRAL AMINO ACIDS TRANSPORTER SMALL SUBUNIT 1 L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;amino acid transmembrane transporter activity#GO:0015171 transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;establishment of localization#GO:0051234;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120843146|UniProtKB=A0ACM8EVE1 A0ACM8EVE1 LOC120843146 PTHR43272:SF113 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;long-chain fatty acid metabolic process#GO:0001676;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 ligase#PC00142 IXOSC|EnsemblGenome=LOC8031839|UniProtKB=A0ACM8DQH4 A0ACM8DQH4 Clc PTHR10639:SF46 CLATHRIN LIGHT CHAIN CLATHRIN LIGHT CHAIN clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 transport#GO:0006810;receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;clathrin-dependent endocytosis#GO:0072583;cellular process#GO:0009987;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192 presynapse#GO:0098793;secretory vesicle#GO:0099503;cytoplasm#GO:0005737;vesicle coat#GO:0030120;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;clathrin vesicle coat#GO:0030125;bounding membrane of organelle#GO:0098588;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;cellular anatomical structure#GO:0110165;clathrin coat#GO:0030118;synapse#GO:0045202;organelle#GO:0043226;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;coated vesicle#GO:0030135;coated membrane#GO:0048475;cell periphery#GO:0071944;membrane#GO:0016020;vesicle membrane#GO:0012506;plasma membrane#GO:0005886;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;synaptic vesicle#GO:0008021;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane coat#GO:0030117 membrane traffic protein#PC00150;vesicle coat protein#PC00235 Huntington disease#P00029>Clathrin#P00798;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 IXOSC|EnsemblGenome=LOC8033190|UniProtKB=A0ACM8E618 A0ACM8E618 LOC8033190 PTHR12370:SF8 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE PHOSPHOLIPASE B-LIKE 3-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC120841799|UniProtKB=A0ACM8ETJ3 A0ACM8ETJ3 LOC120841799 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315005|UniProtKB=A0ACM8DV22 A0ACM8DV22 LOC115315005 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121838405|UniProtKB=A0ACM8G851 A0ACM8G851 LOC121838405 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837590|UniProtKB=A0ACM8G540 A0ACM8G540 LOC121837590 PTHR10068:SF14 BONE MARROW PROTEOGLYCAN ESX-1 SECRETION-ASSOCIATED PROTEIN ESPK extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8037624|UniProtKB=A0ACM8G4P7 A0ACM8G4P7 LOC8037624 PTHR31746:SF3 TRANSMEMBRANE PROTEIN 229 FAMILY MEMBER TRANSMEMBRANE PROTEIN 229B IXOSC|EnsemblGenome=LOC8031668|UniProtKB=A0ACM8DXT9 A0ACM8DXT9 Smn PTHR39267:SF1 SURVIVAL MOTOR NEURON-LIKE PROTEIN 1 SURVIVAL OF MOTOR NEURON IXOSC|EnsemblGenome=LOC115310885|UniProtKB=A0ACM8DQE1 A0ACM8DQE1 PTHR14758:SF1 AGAP005440-PA CENTROSOME-ASSOCIATED FAM110 C-TERMINAL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040419|UniProtKB=A0ACM8EYH4 A0ACM8EYH4 LOC8040419 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;lipid metabolic process#GO:0006629 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC8034361|UniProtKB=A0ACM8DPM8 A0ACM8DPM8 PTHR45747:SF21 HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) HISTONE-LYSINE N-METHYLTRANSFERASE E(Z) catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;histone H3 methyltransferase activity#GO:0140938;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;chromatin binding#GO:0003682;N-methyltransferase activity#GO:0008170;binding#GO:0005488;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253 histone methyltransferase complex#GO:0035097;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;PcG protein complex#GO:0031519;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;methyltransferase complex#GO:0034708 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8040731|UniProtKB=A0ACM8E1U7 A0ACM8E1U7 LOC8040731 PTHR13161:SF15 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;cellular process#GO:0009987;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;alternative mRNA splicing, via spliceosome#GO:0000380;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;ribonucleoprotein complex biogenesis#GO:0022613;mRNA metabolic process#GO:0016071;mRNA cis splicing, via spliceosome#GO:0045292;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8035733|UniProtKB=A0ACM8E544 A0ACM8E544 LOC8035733 PTHR11214:SF314 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8025904|UniProtKB=A0ACM8G7D1 A0ACM8G7D1 LOC8025904 PTHR39077:SF1 DUF4793 DOMAIN-CONTAINING PROTEIN E3 UBIQUITIN-PROTEIN LIGASE APD1-4 MIDDLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849139|UniProtKB=A0ACM8F777 A0ACM8F777 LOC120849139 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8037979|UniProtKB=A0ACM8DK48 A0ACM8DK48 LOC8037979 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115332192|UniProtKB=A0ACM8F1T8 A0ACM8F1T8 LOC115332192 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8031537|UniProtKB=A0ACM8FPR0 A0ACM8FPR0 LOC8031537 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121837832|UniProtKB=A0ACM8G503 A0ACM8G503 LOC121837832 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115318942|UniProtKB=A0ACM8FB58 A0ACM8FB58 LOC115318942 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317656|UniProtKB=A0ACM8F343 A0ACM8F343 LOC115317656 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120847883|UniProtKB=A0ACM8F416 A0ACM8F416 LOC120847883 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120839989|UniProtKB=A0ACM8ENI2 A0ACM8ENI2 LOC120839989 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848218|UniProtKB=A0ACM8FV71 A0ACM8FV71 LOC120848218 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8037100|UniProtKB=A0ACM8FP98 A0ACM8FP98 LOC8037100 PTHR15715:SF47 CENTROSOMAL PROTEIN OF 170 KDA CENTROSOMAL PROTEIN OF 170 KDA-LIKE ISOFORM X1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule anchoring#GO:0034453;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule anchoring at microtubule organizing center#GO:0072393;microtubule-based process#GO:0007017 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8029832|UniProtKB=A0ACM8ECV2 A0ACM8ECV2 Art4 PTHR11006:SF10 PROTEIN ARGININE N-METHYLTRANSFERASE HISTONE-ARGININE METHYLTRANSFERASE CARMER-RELATED protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a protein#GO:0140096;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;regulation of biological process#GO:0050789 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8053896|UniProtKB=A0ACM8FVF0 A0ACM8FVF0 LOC8053896 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8052570|UniProtKB=A0ACM8FHF9 A0ACM8FHF9 LOC8052570 PTHR14196:SF0 ODD-SKIPPED - RELATED PROTEIN ODD-SKIPPED-RELATED 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;anatomical structure development#GO:0048856;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;pattern specification process#GO:0007389;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8029840|UniProtKB=A0ACM8DIX8 A0ACM8DIX8 LOC8029840 PTHR10510:SF11 CYTOCHROME C OXIDASE POLYPEPTIDE 7A CYTOCHROME C OXIDASE SUBUNIT 7A, MITOCHONDRIAL molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;oxidative phosphorylation#GO:0006119;cellular process#GO:0009987;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial envelope#GO:0005740;respiratory chain complex#GO:0098803;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;organelle envelope#GO:0031967 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC115332999|UniProtKB=A0ACM8EJI1 A0ACM8EJI1 LOC115332999 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753 intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777 IXOSC|EnsemblGenome=LOC121836140|UniProtKB=A0ACM8FYT6 A0ACM8FYT6 LOC121836140 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037772|UniProtKB=A0ACM8F1Q4 A0ACM8F1Q4 LOC8037772 PTHR24404:SF128 ZINC FINGER PROTEIN KLUMPFUSS, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115315718|UniProtKB=A0ACM8EGU7 A0ACM8EGU7 LOC115315718 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC115315047|UniProtKB=A0ACM8DUK2 A0ACM8DUK2 LOC115315047 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC121837524|UniProtKB=A0ACM8G551 A0ACM8G551 LOC121837524 PTHR46473:SF28 GH08155P ELRR (EXTRACELLULAR LEUCINE-RICH REPEAT) ONLY IXOSC|EnsemblGenome=LOC115309350|UniProtKB=A0ACM8FR38 A0ACM8FR38 PTHR47333:SF9 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN EGF-CONTAINING FIBULIN-LIKE EXTRACELLULAR MATRIX PROTEIN 1 ISOFORM X1 IXOSC|EnsemblGenome=LOC8027681|UniProtKB=A0ACM8DJA3 A0ACM8DJA3 Trs23 PTHR23249:SF15 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 4 guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192 protein-containing complex#GO:0032991;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;TRAPP complex#GO:0030008 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121838553|UniProtKB=A0ACM8G963 A0ACM8G963 LOC121838553 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220 IXOSC|EnsemblGenome=LOC8031530|UniProtKB=A0ACM8F504 A0ACM8F504 LOC8031530 PTHR19964:SF92 MULTIPLE PDZ DOMAIN PROTEIN PATJ HOMOLOG scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115315757|UniProtKB=A0ACM8FG26 A0ACM8FG26 LOC115315757 PTHR24126:SF14 ANKYRIN REPEAT, PH AND SEC7 DOMAIN CONTAINING PROTEIN SECG-RELATED ANK_REP_REGION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316340|UniProtKB=A0ACM8F9E8 A0ACM8F9E8 LOC115316340 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115311977|UniProtKB=A0ACM8F1F4 A0ACM8F1F4 LOC115311977 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8027928|UniProtKB=A0ACM8E7R2 A0ACM8E7R2 LOC8027928 PTHR13379:SF0 UNCHARACTERIZED DUF1308 UPF0415 PROTEIN C7ORF25 IXOSC|EnsemblGenome=LOC120838445|UniProtKB=A0ACM8EKM9 A0ACM8EKM9 LOC120838445 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310635|UniProtKB=A0ACM8DPZ4 A0ACM8DPZ4 LOC115310635 PTHR13173:SF10 WW DOMAIN BINDING PROTEIN 4 WW DOMAIN-BINDING PROTEIN 4 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 IXOSC|EnsemblGenome=LOC8043449|UniProtKB=A0ACM8E561 A0ACM8E561 LOC8043449 PTHR43658:SF14 SHORT-CHAIN DEHYDROGENASE/REDUCTASE 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING], MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;fatty acid oxidation#GO:0019395;lipid modification#GO:0030258;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;monocarboxylic acid catabolic process#GO:0072329 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8026738|UniProtKB=A0ACM8DVU2 A0ACM8DVU2 LOC8026738 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;isomerase activity#GO:0016853;cis-trans isomerase activity#GO:0016859 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;glutathione metabolic process#GO:0006749;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 isomerase#PC00135 IXOSC|EnsemblGenome=LOC120841686|UniProtKB=A0ACM8ERU4 A0ACM8ERU4 LOC120841686 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121834778|UniProtKB=A0ACM8FR20 A0ACM8FR20 LOC121834778 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115319268|UniProtKB=A0ACM8G3X0 A0ACM8G3X0 LOC115319268 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8053424|UniProtKB=A0ACM8DLT4 A0ACM8DLT4 LOC8053424 PTHR23035:SF1 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97-RELATED CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 97 IXOSC|EnsemblGenome=LOC115319674|UniProtKB=A0ACM8G548 A0ACM8G548 LOC115319674 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120837765|UniProtKB=A0ACM8EHR6 A0ACM8EHR6 LOC120837765 PTHR12316:SF17 NINJURIN-RELATED NINJURIN-A protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632;binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839 cell adhesion#GO:0007155;cellular process#GO:0009987;cell death#GO:0008219;programmed cell death#GO:0012501 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8032869|UniProtKB=A0ACM8EDS9 A0ACM8EDS9 LOC8032869 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8033118|UniProtKB=A0ACM8DNY9 A0ACM8DNY9 LOC8033118 PTHR12918:SF1 CYSTEINE DIOXYGENASE CYSTEINE DIOXYGENASE TYPE 1 cation binding#GO:0043169;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;ferrous iron binding#GO:0008198 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;sulfur compound catabolic process#GO:0044273 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121834019|UniProtKB=A0ACM8FMJ6 A0ACM8FMJ6 PTHR23080:SF153 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315246|UniProtKB=A0ACM8DV28 A0ACM8DV28 LOC115315246 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120841494|UniProtKB=A0ACM8ERC7 A0ACM8ERC7 LOC120841494 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC115317024|UniProtKB=A0ACM8EVH4 A0ACM8EVH4 LOC115317024 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052815|UniProtKB=A0ACM8FIH1 A0ACM8FIH1 LOC8052815 PTHR13357:SF1 SH3 ADAPTER PROTEIN SPIN90 NCK INTERACTING PROTEIN WITH SH3 DOMAIN NCK-INTERACTING PROTEIN WITH SH3 DOMAIN binding#GO:0005488;protein-containing complex binding#GO:0044877 transport#GO:0006810;import into cell#GO:0098657;establishment of localization#GO:0051234;endocytosis#GO:0006897;localization#GO:0051179 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8043034|UniProtKB=A0ACM8E170 A0ACM8E170 LOC8043034 PTHR10738:SF0 PROTEIN ARGININE N-METHYLTRANSFERASE 5 PROTEIN ARGININE N-METHYLTRANSFERASE 5 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120838279|UniProtKB=A0ACM8FTA3 A0ACM8FTA3 LOC120838279 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024525|UniProtKB=A0ACM8DIE3 A0ACM8DIE3 PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;cation binding#GO:0043169;metal ion binding#GO:0046872 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8027745|UniProtKB=A0ACM8FU49 A0ACM8FU49 Gip PTHR11610:SF204 LIPASE PHOSPHOLIPASE A1 1-LIKE PROTEIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120847491|UniProtKB=A0ACM8F3B7 A0ACM8F3B7 LOC120847491 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311803|UniProtKB=A0ACM8G6A0 A0ACM8G6A0 LOC115311803 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120836290|UniProtKB=A0ACM8FCG7 A0ACM8FCG7 LOC120836290 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329991|UniProtKB=A0ACM8FLE4 A0ACM8FLE4 mahj PTHR13129:SF4 VPRBP PROTEIN-RELATED PROTEIN MAHJONG cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 IXOSC|EnsemblGenome=LOC121836147|UniProtKB=A0ACM8FXL7 A0ACM8FXL7 LOC121836147 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC115328623|UniProtKB=A0ACM8E8D4 A0ACM8E8D4 Rpt5 PTHR23073:SF7 26S PROTEASOME REGULATORY SUBUNIT 26S PROTEASOME REGULATORY SUBUNIT 6A isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657 proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proteasome complex#GO:0000502;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC8039362|UniProtKB=A0ACM8EP01 A0ACM8EP01 LOC8039362 PTHR11412:SF166 MACROGLOBULIN / COMPLEMENT OPHIOPHAGUS VENOM FACTOR-LIKE signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;cytokine activity#GO:0005125;protein binding#GO:0005515;chemokine receptor binding#GO:0042379;molecular function activator activity#GO:0140677 immune system process#GO:0002376;innate immune response#GO:0045087;defense response#GO:0006952;response to external stimulus#GO:0009605;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;immune response#GO:0006955;defense response to symbiont#GO:0140546;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121834797|UniProtKB=A0ACM8FRJ7 A0ACM8FRJ7 LOC121834797 PTHR10264:SF136 BAND 7 PROTEIN-RELATED BAND 7 DOMAIN-CONTAINING PROTEIN molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;transporter regulator activity#GO:0141108;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120840445|UniProtKB=A0ACM8ENN3 A0ACM8ENN3 LOC120840445 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate catabolic process#GO:0016052;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318;cellular process#GO:0009987 hydrolase#PC00121;galactosidase#PC00104 IXOSC|EnsemblGenome=LOC115311066|UniProtKB=A0ACM8F9A5 A0ACM8F9A5 LOC115311066 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8027695|UniProtKB=A0ACM8E522 A0ACM8E522 LOC8027695 PTHR24276:SF98 POLYSERASE-RELATED AT20289P-RELATED protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8041687|UniProtKB=A0ACM8E6H2 A0ACM8E6H2 LOC8041687 PTHR46480:SF1 F20B24.22 VOLTAGE-GATED HYDROGEN CHANNEL 1 gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;proton transmembrane transporter activity#GO:0015078;voltage-gated monoatomic cation channel activity#GO:0022843;proton channel activity#GO:0015252;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;proton transmembrane transport#GO:1902600;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC115310270|UniProtKB=A0ACM8DPS3 A0ACM8DPS3 LOC115310270 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8041877|UniProtKB=A0ACM8G1G1 A0ACM8G1G1 LOC8041877 PTHR11699:SF269 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL-LIKE PROTEIN aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 aldehyde metabolic process#GO:0006081;cellular process#GO:0009987;metabolic process#GO:0008152;aldehyde catabolic process#GO:0046185;catabolic process#GO:0009056 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC120847083|UniProtKB=A0ACM8FPP2 A0ACM8FPP2 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053044|UniProtKB=A0ACM8DQ66 A0ACM8DQ66 LOC8053044 PTHR12111:SF1 SPLICING FACTOR YJU2 SPLICING FACTOR YJU2 nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8044123|UniProtKB=A0ACM8F4J9 A0ACM8F4J9 PTHR11360:SF93 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER 7-LIKE PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC121836019|UniProtKB=A0ACM8FW76 A0ACM8FW76 LOC121836019 PTHR10183:SF379 CALPAIN CALPAIN-A-RELATED protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 IXOSC|EnsemblGenome=LOC120850397|UniProtKB=A0ACM8F9X1 A0ACM8F9X1 rudimentary PTHR11405:SF5 CARBAMOYLTRANSFERASE FAMILY MEMBER MULTIFUNCTIONAL PROTEIN CAD ligase activity#GO:0016874;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;ligase activity, forming carbon-nitrogen bonds#GO:0016879;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;pyrimidine nucleobase metabolic process#GO:0006206;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 ligase#PC00142;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Carbamoyl phosphate synthetase#P02925;Arginine biosynthesis#P02728>Carbamoyl phosphate synthase#P02845 IXOSC|EnsemblGenome=LOC120842154|UniProtKB=A0ACM8FSV6 A0ACM8FSV6 LOC120842154 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8032828|UniProtKB=A0ACM8FCQ0 A0ACM8FCQ0 PTHR46283:SF2 E3 UBIQUITIN-PROTEIN LIGASE MARCH5 E3 UBIQUITIN-PROTEIN LIGASE MARCHF5 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;protein modification process#GO:0036211;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;regulation of mitochondrion organization#GO:0010821;protein modification by small protein conjugation#GO:0032446;regulation of organelle organization#GO:0033043;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of anatomical structure morphogenesis#GO:0022603;metabolic process#GO:0008152 mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;membrane#GO:0016020;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;mitochondrial outer membrane#GO:0005741;mitochondrion#GO:0005739;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115329488|UniProtKB=A0ACM8G3D0 A0ACM8G3D0 LOC115329488 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120849673|UniProtKB=A0ACM8FRP7 A0ACM8FRP7 LOC120849673 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;heart development#GO:0007507;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 IXOSC|EnsemblGenome=LOC8052649|UniProtKB=A0ACM8F456 A0ACM8F456 LOC8052649 PTHR11256:SF64 BCL-2 RELATED AT16536P passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cellular process#GO:0050794;cell death#GO:0008219;cellular response to stimulus#GO:0051716;programmed cell death#GO:0012501;apoptotic signaling pathway#GO:0097190;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;positive regulation of cellular process#GO:0048522;intrinsic apoptotic signaling pathway#GO:0097193;cellular response to stress#GO:0033554;signaling#GO:0023052;response to stimulus#GO:0050896;extrinsic apoptotic signaling pathway#GO:0097191;release of cytochrome c from mitochondria#GO:0001836;positive regulation of programmed cell death#GO:0043068;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;cell surface receptor signaling pathway#GO:0007166;regulation of apoptotic process#GO:0042981;mitochondrion organization#GO:0007005;apoptotic mitochondrial changes#GO:0008637;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;negative regulation of programmed cell death#GO:0043069;cellular process#GO:0009987;intrinsic apoptotic signaling pathway in response to DNA damage#GO:0008630;organelle organization#GO:0006996;response to stress#GO:0006950 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 IXOSC|EnsemblGenome=LOC121834814|UniProtKB=A0ACM8FS87 A0ACM8FS87 LOC121834814 PTHR11686:SF77 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115322922|UniProtKB=A0ACM8E390 A0ACM8E390 LOC115322922 PTHR10336:SF80 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN C2 DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;lipase activity#GO:0016298;hydrolase activity#GO:0016787 regulation of cellular process#GO:0050794;phospholipid metabolic process#GO:0006644;metal ion transport#GO:0030001;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;monoatomic cation transport#GO:0006812;localization#GO:0051179;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;establishment of localization#GO:0051234;transport#GO:0006810;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;signal transduction#GO:0007165;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816;metabolic process#GO:0008152 lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115330595|UniProtKB=A0ACM8EBY8 A0ACM8EBY8 LOC115330595 PTHR10915:SF1 SYNDECAN SYNDECAN cell surface#GO:0009986;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8024201|UniProtKB=A0ACM8DI13 A0ACM8DI13 LOC8024201 PTHR13021:SF8 PRE-MRNA-SPLICING FACTOR ISY1 PRE-MRNA-SPLICING FACTOR ISY1 HOMOLOG protein-containing complex organization#GO:0043933;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043 spliceosomal complex#GO:0005681;post-mRNA release spliceosomal complex#GO:0071014;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8037663|UniProtKB=A0ACM8DM71 A0ACM8DM71 MED7 PTHR21428:SF11 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 7 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 RNA polymerase II transcription regulator complex#GO:0090575;core mediator complex#GO:0070847;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8043995|UniProtKB=A0ACM8EIJ5 A0ACM8EIJ5 LOC8043995 PTHR12323:SF0 SR-RELATED CTD ASSOCIATED FACTOR 6 CALCIUM HOMEOSTASIS ENDOPLASMIC RETICULUM PROTEIN homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;calcium ion homeostasis#GO:0055074;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003 cellular anatomical structure#GO:0110165;perinuclear region of cytoplasm#GO:0048471;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115318018|UniProtKB=A0ACM8FD11 A0ACM8FD11 LOC115318018 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8050748|UniProtKB=A0ACM8FVN5 A0ACM8FVN5 LOC8050748 PTHR13743:SF162 BEIGE/BEACH-RELATED NEUROBEACHIN kinase binding#GO:0019900;binding#GO:0005488;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;protein binding#GO:0005515 cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 membrane#GO:0016020;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115326115|UniProtKB=A0ACM8EHA4 A0ACM8EHA4 LOC115326115 PTHR20908:SF1 LD15586P LD15586P IXOSC|EnsemblGenome=LOC115309512|UniProtKB=A0ACM8DNW8 A0ACM8DNW8 LOC115309512 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121045556|UniProtKB=A0ACM8FCH2 A0ACM8FCH2 LOC121045556 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8052154|UniProtKB=A0ACM8DNI2 A0ACM8DNI2 l(2)k14505 PTHR21013:SF10 ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2/ATP12 PROTEIN, MITOCHONDRIAL PRECURSOR ATP SYNTHASE MITOCHONDRIAL F1 COMPLEX ASSEMBLY FACTOR 2 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120840501|UniProtKB=A0ACM8EQB5 A0ACM8EQB5 LOC120840501 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041511|UniProtKB=A0ACM8DKN3 A0ACM8DKN3 LOC8041511 PTHR11848:SF263 TGF-BETA FAMILY PROTEIN DECAPENTAPLEGIC signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;cytokine activity#GO:0005125 cell surface receptor signaling pathway#GO:0007166;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 DPP signaling pathway#P06213>DPP#P06285;DPP-SCW signaling pathway#P06212>DPP full length#P06273;BMP/activin signaling pathway-drosophila#P06211>Full-length BMP orthologous ligand#P06256;BMP/activin signaling pathway-drosophila#P06211>BMP/activin orthologous ligand#P06251;TGF-beta signaling pathway#P00052>TGFbeta#P01286;DPP-SCW signaling pathway#P06212>DPP#P06272;DPP signaling pathway#P06213>DPP full length#P06282 IXOSC|EnsemblGenome=LOC120843074|UniProtKB=A0ACM8EV15 A0ACM8EV15 LOC120843074 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8037702|UniProtKB=A0ACM8DK21 A0ACM8DK21 LOC8037702 PTHR11142:SF33 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE SYNTHASE-LIKE 1 catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824 tRNA modification#GO:0006400;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA modification#GO:0016556;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 lyase#PC00144 IXOSC|EnsemblGenome=LOC115319397|UniProtKB=A0ACM8G820 A0ACM8G820 LOC115319397 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039535|UniProtKB=A0ACM8F901 A0ACM8F901 LOC8039535 PTHR11835:SF60 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;carboxylic acid metabolic process#GO:0019752;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;aerobic respiration#GO:0009060;alcohol metabolic process#GO:0006066;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8023888|UniProtKB=A0ACM8G6A1 A0ACM8G6A1 LOC8023888 PTHR24320:SF285 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 14 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity#GO:0016491;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8027771|UniProtKB=A0ACM8DJC1 A0ACM8DJC1 LOC8027771 PTHR10055:SF1 TRYPTOPHANYL-TRNA SYNTHETASE TRYPTOPHAN--TRNA LIGASE, CYTOPLASMIC catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8050870|UniProtKB=A0ACM8DLL8 A0ACM8DLL8 eRF3 PTHR23115:SF36 TRANSLATION FACTOR G1 TO S PHASE TRANSITION 2 hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;translational termination#GO:0006415;translation#GO:0006412;protein metabolic process#GO:0019538;cellular component disassembly#GO:0022411;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;protein-containing complex disassembly#GO:0032984 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 translation factor#PC00223 IXOSC|EnsemblGenome=LOC115333210|UniProtKB=A0ACM8EED6 A0ACM8EED6 LOC115333210 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120836770|UniProtKB=A0ACM8EFD0 A0ACM8EFD0 LOC120836770 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850650|UniProtKB=A0ACM8FAI3 A0ACM8FAI3 LOC120850650 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121046537|UniProtKB=A0ACM8FE56 A0ACM8FE56 LOC121046537 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120846075|UniProtKB=A0ACM8G7F2 A0ACM8G7F2 LOC120846075 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC115319333|UniProtKB=A0ACM8DZY8 A0ACM8DZY8 LOC115319333 PTHR24031:SF89 RNA HELICASE ATP-DEPENDENT DNA HELICASE DDX31 cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC115315750|UniProtKB=A0ACM8EFQ3 A0ACM8EFQ3 LOC115315750 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115318024|UniProtKB=A0ACM8EZI3 A0ACM8EZI3 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8031595|UniProtKB=A0ACM8DML6 A0ACM8DML6 LOC8031595 PTHR11954:SF49 D-DOPACHROME DECARBOXYLASE MACROPHAGE MIGRATION INHIBITORY FACTOR catalytic activity#GO:0003824;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lyase#PC00144;decarboxylase#PC00089 IXOSC|EnsemblGenome=LOC8041834|UniProtKB=A0ACM8EDR3 A0ACM8EDR3 LOC8041834 PTHR15093:SF1 PROSTATE APOPTOSIS RESPONSE PROTEIN PAR-4 PRKC APOPTOSIS WT1 REGULATOR PROTEIN biological regulation#GO:0065007;regulation of neuron apoptotic process#GO:0043523;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;cellular process#GO:0009987;positive regulation of apoptotic process#GO:0043065;apoptotic signaling pathway#GO:0097190;positive regulation of neuron apoptotic process#GO:0043525;regulation of apoptotic process#GO:0042981;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;signaling#GO:0023052;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;regulation of biological process#GO:0050789;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;cell death#GO:0008219;cell communication#GO:0007154 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115315208|UniProtKB=A0ACM8EWD8 A0ACM8EWD8 LOC115315208 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8029053|UniProtKB=A0ACM8DHI4 A0ACM8DHI4 LOC8029053 PTHR11727:SF30 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 1, MITOCHONDRIAL RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102;N-methyltransferase activity#GO:0008170;transcription regulator activity#GO:0140110;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 DNA-templated transcription initiation#GO:0006352;ribonucleoprotein complex biogenesis#GO:0022613;rRNA modification#GO:0000154;methylation#GO:0032259;RNA metabolic process#GO:0016070;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;mitochondrial gene expression#GO:0140053;rRNA processing#GO:0006364;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mitochondrial transcription#GO:0006390;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8025610|UniProtKB=A0ACM8DTL0 A0ACM8DTL0 LOC8025610 PTHR31661:SF1 SIMILAR TO CDNA SEQUENCE BC052040 CDAN1-INTERACTING NUCLEASE 1 IXOSC|EnsemblGenome=LOC121835091|UniProtKB=A0ACM8FRF3 A0ACM8FRF3 LOC121835091 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC8026409|UniProtKB=A0ACM8EA10 A0ACM8EA10 LOC8026409 PTHR22406:SF7 NASCENT POLYPEPTIDE-ASSOCIATED COMPLEX SUBUNIT ALPHA, MUSCLE-SPECIFIC FORM FLOCCULATION PROTEIN FLO11 microtubule polymerization#GO:0046785;regulation of microtubule polymerization or depolymerization#GO:0031110;microtubule polymerization or depolymerization#GO:0031109;positive regulation of cellular process#GO:0048522;positive regulation of protein polymerization#GO:0032273;biological regulation#GO:0065007;regulation of microtubule-based process#GO:0032886;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;cellular component assembly#GO:0022607;regulation of microtubule cytoskeleton organization#GO:0070507;cytoskeleton organization#GO:0007010;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of microtubule polymerization#GO:0031113;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;microtubule nucleation#GO:0007020;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cytoplasmic microtubule organization#GO:0031122;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087 microtubule cytoskeleton#GO:0015630;microtubule end#GO:1990752;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512 IXOSC|EnsemblGenome=LOC115317158|UniProtKB=A0ACM8EFS5 A0ACM8EFS5 LOC115317158 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121835798|UniProtKB=A0ACM8FWM4 A0ACM8FWM4 LOC121835798 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024504|UniProtKB=A0ACM8EB84 A0ACM8EB84 LOC8024504 PTHR47958:SF11 ATP-DEPENDENT RNA HELICASE DBP3 RNA HELICASE helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657 cellular process involved in reproduction in multicellular organism#GO:0022412;reproductive process#GO:0022414;cell development#GO:0048468;gamete generation#GO:0007276;cell differentiation#GO:0030154;cellular process#GO:0009987;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006;multicellular organismal reproductive process#GO:0048609;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;sexual reproduction#GO:0019953;developmental process#GO:0032502 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;P granule#GO:0043186;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8039678|UniProtKB=A0ACM8E7E4 A0ACM8E7E4 LOC8039678 PTHR24394:SF64 ZINC FINGER PROTEIN CENTROSOME-ASSOCIATED ZINC FINGER PROTEIN CP190 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8028659|UniProtKB=A0ACM8DN71 A0ACM8DN71 Tgs1 PTHR14741:SF32 S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED TRIMETHYLGUANOSINE SYNTHASE transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA methylation#GO:0001510;methylation#GO:0032259;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC115331194|UniProtKB=A0ACM8F2N0 A0ACM8F2N0 LOC115331194 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8040572|UniProtKB=A0ACM8DN04 A0ACM8DN04 Pcyt2 PTHR10739:SF13 CYTIDYLYLTRANSFERASE CHOLINE-PHOSPHATE CYTIDYLYLTRANSFERASE phosphatidylcholine binding#GO:0031210;nucleotidyltransferase activity#GO:0016779;transferase activity#GO:0016740;catalytic activity#GO:0003824;phospholipid binding#GO:0005543;transferase activity, transferring phosphorus-containing groups#GO:0016772;lipid binding#GO:0008289;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488 transferase#PC00220 IXOSC|EnsemblGenome=LOC115320401|UniProtKB=A0ACM8E0R7 A0ACM8E0R7 LOC115320401 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8052873|UniProtKB=A0ACM8E7N3 A0ACM8E7N3 LOC8052873 PTHR24412:SF513 KELCH PROTEIN SUBFAMILY NOT NAMED enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115320298|UniProtKB=A0ACM8EKP7 A0ACM8EKP7 LOC115320298 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834493|UniProtKB=A0ACM8FPU7 A0ACM8FPU7 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115311092|UniProtKB=A0ACM8G7D6 A0ACM8G7D6 LOC115311092 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8034871|UniProtKB=A0ACM8DTF4 A0ACM8DTF4 LOC8034871 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8032558|UniProtKB=A0ACM8FD93 A0ACM8FD93 LOC8032558 PTHR14255:SF4 CEREBLON PROTEIN CEREBLON ubiquitin-like ligase-substrate adaptor activity#GO:1990756;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;protein metabolic process#GO:0019538;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;proteasomal protein catabolic process#GO:0010498;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular membrane-bounded organelle#GO:0043231 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8026284|UniProtKB=A0ACM8FF58 A0ACM8FF58 LOC8026284 PTHR12052:SF4 THIOREDOXIN-LIKE PROTEN 4A, 4B THIOREDOXIN-LIKE PROTEIN 4B RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 spliceosomal complex#GO:0005681;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;spliceosomal tri-snRNP complex#GO:0097526;spliceosomal snRNP complex#GO:0097525;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small nuclear ribonucleoprotein complex#GO:0030532;nucleus#GO:0005634;U4/U6 x U5 tri-snRNP complex#GO:0046540;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120842111|UniProtKB=A0ACM8EU69 A0ACM8EU69 LOC120842111 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319976|UniProtKB=A0ACM8G379 A0ACM8G379 LOC115319976 PTHR11183:SF204 GLYCOGENIN SUBFAMILY MEMBER GLYCOGENIN GLUCOSYLTRANSFERASE glucosyltransferase activity#GO:0046527;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;UDP-glucosyltransferase activity#GO:0035251;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8041380|UniProtKB=A0ACM8ECR5 A0ACM8ECR5 LOC8041380 PTHR11616:SF303 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER INE metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;nitrogen compound transport#GO:0071705;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;import into cell#GO:0098657;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;import across plasma membrane#GO:0098739;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8040811|UniProtKB=A0ACM8E663 A0ACM8E663 LOC8040811 PTHR13667:SF5 HOMOLOC-13 WD REPEAT-CONTAINING AND PLANAR CELL POLARITY EFFECTOR PROTEIN FRITZ HOMOLOG IXOSC|EnsemblGenome=LOC115318171|UniProtKB=A0ACM8F1Q1 A0ACM8F1Q1 LOC115318171 PTHR10643:SF2 KINETOCHORE PROTEIN NDC80 KINETOCHORE PROTEIN NDC80 HOMOLOG attachment of mitotic spindle microtubules to kinetochore#GO:0051315;nuclear division#GO:0000280;organelle localization#GO:0051640;organelle fission#GO:0048285;localization#GO:0051179;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;mitotic metaphase chromosome alignment#GO:0007080;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;chromosome segregation#GO:0007059;metaphase chromosome alignment#GO:0051310;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;attachment of spindle microtubules to kinetochore#GO:0008608;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;chromosome localization#GO:0050000 intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;outer kinetochore#GO:0000940;membraneless organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC121837547|UniProtKB=A0ACM8G4Y1 A0ACM8G4Y1 LOC121837547 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030636|UniProtKB=A0ACM8DHA8 A0ACM8DHA8 Saysd1 PTHR13527:SF0 SAYSVFN DOMAIN-CONTAINING PROTEIN 1 SAYSVFN DOMAIN-CONTAINING PROTEIN 1 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 gene expression#GO:0010467;biosynthetic process#GO:0009058;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cytoplasmic translation#GO:0002181;protein quality control for misfolded or incompletely synthesized proteins#GO:0006515;catabolic process#GO:0009056;protein biosynthetic process#GO:0160307;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;rescue of stalled cytosolic ribosome#GO:0072344;organelle disassembly#GO:1903008;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;translation#GO:0006412 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8025741|UniProtKB=A0ACM8ES34 A0ACM8ES34 LOC8025741 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC120844876|UniProtKB=A0ACM8EZT9 A0ACM8EZT9 LOC120844876 PTHR10844:SF19 CAVEOLIN CAVEOLIN-2 cellular component organization or biogenesis#GO:0071840;plasma membrane organization#GO:0007009;membrane assembly#GO:0071709;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component assembly#GO:0022607 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8024753|UniProtKB=A0ACM8DUB1 A0ACM8DUB1 LOC8024753 PTHR46024:SF1 HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS HISTONE-LYSINE N-METHYLTRANSFERASE EGGLESS catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170 negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8033257|UniProtKB=A0ACM8DVZ7 A0ACM8DVZ7 PTHR46724:SF3 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 9-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8050686|UniProtKB=A0ACM8DVC5 A0ACM8DVC5 LOC8050686 PTHR46190:SF1 SI:CH211-201H21.5-RELATED SI:CH211-201H21.5 IXOSC|EnsemblGenome=LOC8024868|UniProtKB=A0ACM8E1H5 A0ACM8E1H5 LOC8024868 PTHR24409:SF448 ZINC FINGER PROTEIN 142 C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120837311|UniProtKB=A0ACM8EI11 A0ACM8EI11 LOC120837311 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115330169|UniProtKB=A0ACM8F3A0 A0ACM8F3A0 LOC115330169 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8024269|UniProtKB=A0ACM8E3M9 A0ACM8E3M9 CCT3 PTHR11353:SF24 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT GAMMA macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 chaperonin-containing T-complex#GO:0005832;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein folding chaperone complex#GO:0101031;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperonin#PC00073 IXOSC|EnsemblGenome=LOC8053786|UniProtKB=A0ACM8E5W9 A0ACM8E5W9 LOC8053786 PTHR24025:SF23 DESMOGLEIN FAMILY MEMBER NEURAL-CADHERIN cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell-cell junction#GO:0005911;anchoring junction#GO:0070161;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 cadherin#PC00057 Cadherin signaling pathway#P00012>Cadherin#P00471;Wnt signaling pathway#P00057>Cadherin#P01440 IXOSC|EnsemblGenome=LOC8023555|UniProtKB=A0ACM8FDM6 A0ACM8FDM6 LOC8023555 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115320516|UniProtKB=A0ACM8FRN6 A0ACM8FRN6 Ctu1 PTHR11807:SF12 ATPASES OF THE PP SUPERFAMILY-RELATED CYTOPLASMIC TRNA 2-THIOLATION PROTEIN 1 nucleic acid binding#GO:0003676;binding#GO:0005488;tRNA binding#GO:0000049;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble position uridine thiolation#GO:0002143;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;sulfurtransferase complex#GO:1990228;cytoplasm#GO:0005737;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC115318922|UniProtKB=A0ACM8DZ38 A0ACM8DZ38 Alg7 PTHR10571:SF0 UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE UDP-N-ACETYLGLUCOSAMINE--DOLICHYL-PHOSPHATE N-ACETYLGLUCOSAMINEPHOSPHOTRANSFERASE phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115317670|UniProtKB=A0ACM8EUU8 A0ACM8EUU8 PpD3 PTHR45668:SF5 SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 5 phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;hydrolase activity#GO:0016787 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC121835415|UniProtKB=A0ACM8FTT8 A0ACM8FTT8 LOC121835415 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120842590|UniProtKB=A0ACM8FUE5 A0ACM8FUE5 LOC120842590 PTHR31475:SF5 UPF0462 PROTEIN UPF0462 PROTEIN C4ORF33 HOMOLOG IXOSC|EnsemblGenome=LOC8043420|UniProtKB=A0ACM8EQY4 A0ACM8EQY4 LOC8043420 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115313160|UniProtKB=A0ACM8EQL5 A0ACM8EQL5 LOC115313160 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8036192|UniProtKB=A0ACM8DH97 A0ACM8DH97 Rad1 PTHR10870:SF0 CELL CYCLE CHECKPOINT PROTEIN RAD1 CELL CYCLE CHECKPOINT PROTEIN RAD1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;cellular response to stress#GO:0033554;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;negative regulation of cell cycle#GO:0045786;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of cell cycle phase transition#GO:1901987;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;DNA integrity checkpoint signaling#GO:0031570;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;condensed chromosome#GO:0000793;condensed nuclear chromosome#GO:0000794;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 IXOSC|EnsemblGenome=LOC8041260|UniProtKB=A0ACM8DRJ7 A0ACM8DRJ7 l(2)09851 PTHR45903:SF1 GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1 GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;ribosome biogenesis#GO:0042254;cellular component biogenesis#GO:0044085 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120849653|UniProtKB=A0ACM8F754 A0ACM8F754 LOC120849653 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN system development#GO:0048731;animal organ development#GO:0048513;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;post-embryonic development#GO:0009791;cell adhesion#GO:0007155;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;circulatory system development#GO:0072359;heart development#GO:0007507;cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 IXOSC|EnsemblGenome=LOC8029837|UniProtKB=A0ACM8DM90 A0ACM8DM90 LOC8029837 PTHR46360:SF1 DISKS LARGE HOMOLOG 5 DISKS LARGE HOMOLOG 5 negative regulation of cell communication#GO:0010648;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of hippo signaling#GO:0035330;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8029701|UniProtKB=A0ACM8ELY7 A0ACM8ELY7 LOC8029701 PTHR48021:SF47 FAMILY NOT NAMED GH17672P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8031670|UniProtKB=A0ACM8DXA5 A0ACM8DXA5 Mob4 PTHR22599:SF1 MPS ONE BINDER KINASE ACTIVATOR-LIKE MOB MOB-LIKE PROTEIN PHOCEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC120849270|UniProtKB=A0ACM8F7I1 A0ACM8F7I1 LOC120849270 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8050797|UniProtKB=A0ACM8DRM4 A0ACM8DRM4 LOC8050797 PTHR21215:SF0 LD36024P LD36024P IXOSC|EnsemblGenome=LOC120847727|UniProtKB=A0ACM8G1Y9 A0ACM8G1Y9 rin PTHR10693:SF88 RAS GTPASE-ACTIVATING PROTEIN-BINDING PROTEIN AT27578P nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729;RNA binding#GO:0003723 organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607 cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;cytosol#GO:0005829 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115321090|UniProtKB=A0ACM8E1N2 A0ACM8E1N2 LOC115321090 PTHR23033:SF14 BETA1,3-GALACTOSYLTRANSFERASE GLYCOPROTEIN-N-ACETYLGALACTOSAMINE 3-BETA-GALACTOSYLTRANSFERASE 1-RELATED catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;galactosyltransferase activity#GO:0008378;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 transferase#PC00220 IXOSC|EnsemblGenome=LOC121837497|UniProtKB=A0ACM8G3C2 A0ACM8G3C2 LOC121837497 PTHR24329:SF585 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;neuron differentiation#GO:0030182;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115314101|UniProtKB=A0ACM8DTR0 A0ACM8DTR0 LOC115314101 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115310832|UniProtKB=A0ACM8EXJ2 A0ACM8EXJ2 LOC115310832 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115309617|UniProtKB=A0ACM8DNV3 A0ACM8DNV3 LOC115309617 PTHR16007:SF15 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B-LIKE IXOSC|EnsemblGenome=LOC121837938|UniProtKB=A0ACM8G5G8 A0ACM8G5G8 LOC121837938 PTHR11195:SF13 DESTABILASE-RELATED LYSOZYME lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;peptidoglycan muralytic activity#GO:0061783 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8053821|UniProtKB=A0ACM8F0C3 A0ACM8F0C3 EMC4 PTHR19315:SF9 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 ER MEMBRANE PROTEIN COMPLEX SUBUNIT 4 protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029 endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;endoplasmic reticulum protein-containing complex#GO:0140534;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121048282|UniProtKB=A0ACM8FI32 A0ACM8FI32 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029938|UniProtKB=A0ACM8E0B1 A0ACM8E0B1 LOC8029938 PTHR24207:SF2 ZYX102 PROTEIN ZYX102 PROTEIN cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 membraneless organelle#GO:0043228;actin filament bundle#GO:0032432;cell junction#GO:0030054;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;stress fiber#GO:0001725;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;focal adhesion#GO:0005925;cell-substrate junction#GO:0030055;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629;actomyosin#GO:0042641 kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC121836079|UniProtKB=A0ACM8FWK1 A0ACM8FWK1 LOC121836079 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8026346|UniProtKB=A0ACM8EHJ2 A0ACM8EHJ2 LOC8026346 PTHR43520:SF35 ATP7, ISOFORM B P-TYPE CU(+) TRANSPORTER transmembrane transporter activity#GO:0022857;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ion binding#GO:0043167;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;cation binding#GO:0043169;copper ion binding#GO:0005507;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;metal ion transmembrane transporter activity#GO:0046873;transition metal ion transmembrane transporter activity#GO:0046915;binding#GO:0005488;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;metal ion binding#GO:0046872;monoatomic cation transmembrane transporter activity#GO:0008324 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;copper ion transmembrane transport#GO:0035434;metal ion transport#GO:0030001;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115328468|UniProtKB=A0ACM8FDS9 A0ACM8FDS9 LOC115328468 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115325934|UniProtKB=A0ACM8E5C7 A0ACM8E5C7 LOC115325934 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115317545|UniProtKB=A0ACM8EYK9 A0ACM8EYK9 LOC115317545 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120844735|UniProtKB=A0ACM8EZL5 A0ACM8EZL5 LOC120844735 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8052756|UniProtKB=A0ACM8EHJ5 A0ACM8EHJ5 Sos PTHR23113:SF363 GUANINE NUCLEOTIDE EXCHANGE FACTOR PROTEIN SON OF SEVENLESS guanyl-nucleotide exchange factor activity#GO:0005085;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;Ras protein signal transduction#GO:0007265;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 Ras Pathway#P04393>SOS#P04552;Integrin signalling pathway#P00034>SOS#P00920;PDGF signaling pathway#P00047>SOS#P01159;EGF receptor signaling pathway#P00018>SOS#P00558;Angiogenesis#P00005>SOS-1#P00193;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>SOS#P00883;FGF signaling pathway#P00021>SOS#P00641 IXOSC|EnsemblGenome=LOC121047945|UniProtKB=A0ACM8FI63 A0ACM8FI63 LOC121047945 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313467|UniProtKB=A0ACM8EP61 A0ACM8EP61 Graf PTHR12552:SF1 OLIGOPHRENIN 1 RHO GTPASE-ACTIVATING PROTEIN GRAF enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 IXOSC|EnsemblGenome=LOC121833852|UniProtKB=A0ACM8FNJ3 A0ACM8FNJ3 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097 organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;homologous recombination#GO:0035825;reproductive process#GO:0022414;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8024483|UniProtKB=A0ACM8E9U0 A0ACM8E9U0 LOC8024483 PTHR45877:SF2 E3 UBIQUITIN-PROTEIN LIGASE SIAH2 E3 UBIQUITIN-PROTEIN LIGASE SINA-RELATED ubiquitin-protein ligase#PC00234 Wnt signaling pathway#P00057>SIAH-1#P01433 IXOSC|EnsemblGenome=LOC8042304|UniProtKB=A0ACM8ECN7 A0ACM8ECN7 Vav PTHR45818:SF3 PROTEIN VAV PROTEIN VAV molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;guanyl-nucleotide exchange factor activity#GO:0005085 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;cell motility#GO:0048870;regulation of cellular process#GO:0050794;cell migration#GO:0016477 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 PDGF signaling pathway#P00047>Vav#P01169 IXOSC|EnsemblGenome=LOC120844618|UniProtKB=A0ACM8EZ86 A0ACM8EZ86 LOC120844618 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120848640|UniProtKB=A0ACM8FGX1 A0ACM8FGX1 LOC120848640 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837919|UniProtKB=A0ACM8G5C1 A0ACM8G5C1 LOC121837919 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763 biosynthetic process#GO:0009058;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152 IXOSC|EnsemblGenome=LOC8036157|UniProtKB=A0ACM8DMI6 A0ACM8DMI6 PTHR43173:SF28 ABC1 FAMILY PROTEIN AARF DOMAIN CONTAINING KINASE 5 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121836099|UniProtKB=A0ACM8FYH8 A0ACM8FYH8 LOC121836099 PTHR36694:SF11 PASIFLORA 1, ISOFORM A-RELATED LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4B-LIKE ISOFORM X1 IXOSC|EnsemblGenome=LOC120838190|UniProtKB=A0ACM8EJD5 A0ACM8EJD5 LOC120838190 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8025706|UniProtKB=A0ACM8EK57 A0ACM8EK57 LOC8025706 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791 nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC8050765|UniProtKB=A0ACM8G218 A0ACM8G218 LOC8050765 PTHR13058:SF19 THREE PRIME REPAIR EXONUCLEASE 1, 2 LD40940P catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA exonuclease activity#GO:0004529;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;exonuclease activity#GO:0004527;hydrolase activity#GO:0016787;3'-5'-DNA exonuclease activity#GO:0008296;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;nuclease activity#GO:0004518 nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA catabolic process#GO:0006308 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115331745|UniProtKB=A0ACM8EDU1 A0ACM8EDU1 LOC115331745 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8052041|UniProtKB=A0ACM8EE21 A0ACM8EE21 LOC8052041 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281 peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC120836011|UniProtKB=A0ACM8F4N4 A0ACM8F4N4 LOC120836011 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8025640|UniProtKB=A0ACM8E2Y0 A0ACM8E2Y0 LOC8025640 PTHR48034:SF40 TRANSFORMER-2 SEX-DETERMINING PROTEIN-RELATED SERINE AND ARGININE RICH SPLICING FACTOR 10 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8052010|UniProtKB=A0ACM8DLH6 A0ACM8DLH6 RpL12 PTHR11661:SF2 60S RIBOSOMAL PROTEIN L12 LARGE RIBOSOMAL SUBUNIT PROTEIN UL11 binding#GO:0005488;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121047071|UniProtKB=A0ACM8FFE4 A0ACM8FFE4 LOC121047071 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030235|UniProtKB=A0ACM8DXK3 A0ACM8DXK3 LOC8030235 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC-RELATED binding#GO:0005488;protein binding#GO:0005515 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;cellular anatomical structure#GO:0110165;organelle#GO:0043226;dynein complex#GO:0030286;cytoplasmic dynein complex#GO:0005868;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 IXOSC|EnsemblGenome=LOC115329666|UniProtKB=A0ACM8ELH5 A0ACM8ELH5 LOC115329666 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8043975|UniProtKB=A0ACM8FKL0 A0ACM8FKL0 pck PTHR21284:SF13 EG:80H7.2 PROTEIN EG:80H7.2 PROTEIN cellular component organization#GO:0016043;cell junction assembly#GO:0034329;cell junction organization#GO:0034330;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;cell-cell junction assembly#GO:0007043;developmental process#GO:0032502;cell-cell junction organization#GO:0045216;regulation of anatomical structure size#GO:0090066;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840 anchoring junction#GO:0070161;tight junction#GO:0070160;cellular anatomical structure#GO:0110165;cell junction#GO:0030054;cell-cell junction#GO:0005911;apical junction complex#GO:0043296 IXOSC|EnsemblGenome=LOC120847802|UniProtKB=A0ACM8F4W1 A0ACM8F4W1 LOC120847802 PTHR10751:SF144 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824 heterotrimeric G-protein#PC00117;G-protein#PC00020 IXOSC|EnsemblGenome=LOC115311481|UniProtKB=A0ACM8DR07 A0ACM8DR07 mRpL47 PTHR21183:SF18 RIBOSOMAL PROTEIN L47, MITOCHONDRIAL-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL29M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8036586|UniProtKB=A0ACM8ECA0 A0ACM8ECA0 LOC8036586 PTHR11036:SF127 SEMAPHORIN SEMAPHORIN-1A protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;response to stimulus#GO:0050896;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;signaling#GO:0023052;cellular component organization#GO:0016043;positive regulation of cell motility#GO:2000147;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cell projection morphogenesis#GO:0048858;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;taxis#GO:0042330;response to chemical#GO:0042221;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;anatomical structure development#GO:0048856;cell communication#GO:0007154;regulation of cell motility#GO:2000145;system development#GO:0048731;chemotaxis#GO:0006935;regulation of cellular process#GO:0050794;locomotion#GO:0040011;cellular response to stimulus#GO:0051716;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neuron projection morphogenesis#GO:0048812;regulation of cell migration#GO:0030334;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;biological regulation#GO:0065007;axon development#GO:0061564;axon guidance#GO:0007411;positive regulation of cell migration#GO:0030335;positive regulation of cellular process#GO:0048522 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane-bound signaling molecule#PC00152 IXOSC|EnsemblGenome=LOC120836371|UniProtKB=A0ACM8FX17 A0ACM8FX17 LOC120836371 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8030317|UniProtKB=A0ACM8G334 A0ACM8G334 LOC8030317 PTHR24353:SF161 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE SUBFAMILY NOT NAMED biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cell surface receptor signaling pathway#GO:0007166 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKG#P00567 IXOSC|EnsemblGenome=LOC8041568|UniProtKB=A0ACM8EBI8 A0ACM8EBI8 LOC8041568 PTHR23101:SF104 RAB GDP/GTP EXCHANGE FACTOR PROTEIN SPRINT molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme binding#GO:0019899;binding#GO:0005488;guanyl-nucleotide exchange factor activity#GO:0005085;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 vesicle#GO:0031982;intracellular vesicle#GO:0097708;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227 guanyl-nucleotide exchange factor#PC00113;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8040864|UniProtKB=A0ACM8DR64 A0ACM8DR64 LOC8040864 PTHR47977:SF90 RAS-RELATED PROTEIN RAB RAS AND EF-HAND DOMAIN-CONTAINING PROTEIN HOMOLOG ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;small molecule binding#GO:0036094;anion binding#GO:0043168;GTPase activity#GO:0003924;ion binding#GO:0043167;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265 localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;transport#GO:0006810;cellular process#GO:0009987 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC115308488|UniProtKB=A0ACM8DMJ3 A0ACM8DMJ3 LOC115308488 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837072|UniProtKB=A0ACM8G2Y7 A0ACM8G2Y7 LOC121837072 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8025288|UniProtKB=A0ACM8E1R9 A0ACM8E1R9 LOC8025288 PTHR13395:SF6 SISTER CHROMATID COHESION PROTEIN DCC1-RELATED SISTER CHROMATID COHESION PROTEIN DCC1 cellular component organization or biogenesis#GO:0071840;sister chromatid cohesion#GO:0007062;chromosome organization#GO:0051276;mitotic sister chromatid cohesion#GO:0007064;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;chromosome, centromeric region#GO:0000775;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;replication origin binding protein#PC00199 IXOSC|EnsemblGenome=LOC8024860|UniProtKB=A0ACM8E0P1 A0ACM8E0P1 LOC8024860 PTHR22988:SF77 MYOTONIC DYSTROPHY S/T KINASE-RELATED PARAMYOSIN, LONG FORM protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 regulation of actin filament length#GO:0030832;actin filament-based process#GO:0030029;regulation of biological quality#GO:0065008;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle#GO:0007049;cellular component organization#GO:0016043;actomyosin structure organization#GO:0031032;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of anatomical structure size#GO:0090066;regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of actin polymerization or depolymerization#GO:0008064;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of actin cytoskeleton organization#GO:0032956 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115317073|UniProtKB=A0ACM8EGF8 A0ACM8EGF8 LOC115317073 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115332118|UniProtKB=A0ACM8FRQ1 A0ACM8FRQ1 LOC115332118 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320260|UniProtKB=A0ACM8F6U6 A0ACM8F6U6 LOC115320260 PTHR10336:SF80 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN C2 DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620 primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;metal ion transport#GO:0030001;phospholipid metabolic process#GO:0006644;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;localization#GO:0051179;intracellular signal transduction#GO:0035556;organophosphate metabolic process#GO:0019637;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;transport#GO:0006810;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629;establishment of localization#GO:0051234;phosphorus metabolic process#GO:0006793;calcium ion transmembrane transport#GO:0070588;regulation of biological process#GO:0050789;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;release of sequestered calcium ion into cytosol#GO:0051209;signal transduction#GO:0007165;glycerophospholipid metabolic process#GO:0006650;monoatomic cation transmembrane transport#GO:0098655;metabolic process#GO:0008152;calcium ion transmembrane import into cytosol#GO:0097553;calcium ion transport#GO:0006816 lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120846537|UniProtKB=A0ACM8FJG5 A0ACM8FJG5 LOC120846537 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8023732|UniProtKB=A0ACM8DTG4 A0ACM8DTG4 LOC8023732 PTHR24171:SF10 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8029929|UniProtKB=A0ACM8G6M6 A0ACM8G6M6 LOC8029929 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC8040917|UniProtKB=A0ACM8E0V7 A0ACM8E0V7 LOC8040917 PTHR13510:SF44 FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED RABENOSYN-5 IXOSC|EnsemblGenome=LOC8033661|UniProtKB=A0ACM8DUP2 A0ACM8DUP2 LOC8033661 PTHR36562:SF5 SERINE/ARGININE REPETITIVE MATRIX 2 SERINE_ARGININE REPETITIVE MATRIX 2 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8051536|UniProtKB=A0ACM8EYD0 A0ACM8EYD0 LOC8051536 PTHR43157:SF72 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED RETINOL DEHYDROGENASE 14-LIKE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8036000|UniProtKB=A0ACM8E8L3 A0ACM8E8L3 LOC8036000 PTHR13140:SF679 MYOSIN UNCONVENTIONAL MYOSIN IC microfilament motor activity#GO:0000146;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657;macromolecular conformation isomerase activity#GO:0120543;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 transport#GO:0006810;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;import into cell#GO:0098657;actin filament-based movement#GO:0030048;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cytoskeleton organization#GO:0007010;endocytosis#GO:0006897;actin cytoskeleton organization#GO:0030036 intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microvillus#GO:0005902;actin-based cell projection#GO:0098858;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cell periphery#GO:0071944;membrane#GO:0016020 actin binding motor protein#PC00040 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC8041650|UniProtKB=A0ACM8EC14 A0ACM8EC14 LOC8041650 PTHR23043:SF17 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA PROTEIN SIMILAR DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;response to decreased oxygen levels#GO:0036293;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;cellular response to hypoxia#GO:0071456;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of biosynthetic process#GO:0009889;intracellular chemical homeostasis#GO:0055082;response to hypoxia#GO:0001666;cellular homeostasis#GO:0019725;regulation of gene expression#GO:0010468;chemical homeostasis#GO:0048878;regulation of nucleobase-containing compound metabolic process#GO:0019219;response to chemical#GO:0042221;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;response to stress#GO:0006950;cellular process#GO:0009987 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8031641|UniProtKB=A0ACM8DIH4 A0ACM8DIH4 Lsm12a PTHR13542:SF0 LSM12 HOMOLOG PROTEIN LSM12 IXOSC|EnsemblGenome=LOC121838428|UniProtKB=A0ACM8G885 A0ACM8G885 LOC121838428 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121836775|UniProtKB=A0ACM8G0I0 A0ACM8G0I0 LOC121836775 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8051879|UniProtKB=A0ACM8EE56 A0ACM8EE56 LOC8051879 PTHR46551:SF1 SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN SAP DOMAIN-CONTAINING RIBONUCLEOPROTEIN RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115324247|UniProtKB=A0ACM8E4G3 A0ACM8E4G3 Dlish PTHR46037:SF8 PROTEIN ENHANCER OF SEVENLESS 2B SH3 DOMAIN-CONTAINING PROTEIN DLISH-LIKE protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;growth factor receptor binding#GO:0070851 cell communication#GO:0007154;regulation of MAPK cascade#GO:0043408;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;cell periphery#GO:0071944;nucleus#GO:0005634;COP9 signalosome#GO:0008180;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC8042177|UniProtKB=A0ACM8FY39 A0ACM8FY39 LOC8042177 PTHR13859:SF11 ATROPHIN-RELATED GRUNGE, ISOFORM J transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8023159|UniProtKB=A0ACM8DGH0 A0ACM8DGH0 LOC8023159 PTHR45888:SF18 HL01030P-RELATED PHD FINGER PROTEIN 10 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 IXOSC|EnsemblGenome=LOC115313916|UniProtKB=A0ACM8EJ90 A0ACM8EJ90 Rcd1 PTHR13136:SF16 TESTIS DEVELOPMENT PROTEIN PRTD KAT8 REGULATORY NSL COMPLEX SUBUNIT 3 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604 chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;NSL complex#GO:0044545;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC8027504|UniProtKB=A0ACM8EH84 A0ACM8EH84 LOC8027504 PTHR11552:SF147 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE GLUCOSE-METHANOL-CHOLINE OXIDOREDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115328467|UniProtKB=A0ACM8E858 A0ACM8E858 LOC115328467 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036206|UniProtKB=A0ACM8EAI8 A0ACM8EAI8 LOC8036206 PTHR24223:SF447 ATP-BINDING CASSETTE SUB-FAMILY C MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 5 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cellular anatomical structure#GO:0110165;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8026407|UniProtKB=A0ACM8EA60 A0ACM8EA60 LOC8026407 PTHR13526:SF8 TRANSCRIPTION FACTOR SPT20 HOMOLOG SPT20 HOMOLOG, SAGA COMPLEX COMPONENT-RELATED transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein acetyltransferase complex#GO:0031248;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;SAGA-type complex#GO:0070461;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;chromatin#GO:0000785;SAGA complex#GO:0000124;peptidase complex#GO:1905368;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8040267|UniProtKB=A0ACM8E065 A0ACM8E065 LOC8040267 PTHR12162:SF0 NIBRIN-RELATED NIBRIN DNA binding#GO:0003677;damaged DNA binding#GO:0003684;nucleic acid binding#GO:0003676;binding#GO:0005488 DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;mitotic G2/M transition checkpoint#GO:0044818;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;recombinational repair#GO:0000725;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;mitotic DNA damage checkpoint signaling#GO:0044773;cellular response to stimulus#GO:0051716;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;negative regulation of cell cycle G2/M phase transition#GO:1902750;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;signal transduction in response to DNA damage#GO:0042770;regulation of biological process#GO:0050789;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;signaling#GO:0023052;response to stimulus#GO:0050896 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 IXOSC|EnsemblGenome=LOC8052146|UniProtKB=A0ACM8DYT4 A0ACM8DYT4 LOC8052146 PTHR24412:SF489 KELCH PROTEIN RING CANAL KELCH PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115323834|UniProtKB=A0ACM8E431 A0ACM8E431 LOC115323834 PTHR46569:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRAIP E3 UBIQUITIN-PROTEIN LIGASE TRAIP acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;replication fork processing#GO:0031297;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation#GO:0032446;DNA replication#GO:0006260;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification by small protein conjugation or removal#GO:0070647;DNA-templated DNA replication#GO:0006261;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115330141|UniProtKB=A0ACM8EP49 A0ACM8EP49 PTHR45842:SF33 SYNAPTIC ADHESION-LIKE MOLECULE SALM LEUCINE-RICH REPEATS AND IMMUNOGLOBULIN-LIKE DOMAINS 3 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC115325239|UniProtKB=A0ACM8E4M1 A0ACM8E4M1 LOC115325239 PTHR21330:SF1 E3 SUMO-PROTEIN LIGASE NSE2 E3 SUMO-PROTEIN LIGASE NSE2 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659 cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;double-strand break repair#GO:0006302;protein sumoylation#GO:0016925;macromolecule metabolic process#GO:0043170;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;protein modification by small protein conjugation#GO:0032446;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121834091|UniProtKB=A0ACM8FNX2 A0ACM8FNX2 PTHR19818:SF157 ZINC FINGER PROTEIN ZIC AND GLI ZINC FINGER PROTEIN 84-LIKE sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120848106|UniProtKB=A0ACM8F572 A0ACM8F572 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115313134|UniProtKB=A0ACM8EH45 A0ACM8EH45 LOC115313134 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8028192|UniProtKB=A0ACM8E8N6 A0ACM8E8N6 LOC8028192 PTHR12881:SF10 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 1 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8031391|UniProtKB=A0ACM8E2H9 A0ACM8E2H9 shot PTHR11915:SF459 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN PH DOMAIN-CONTAINING PROTEIN actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8031456|UniProtKB=A0ACM8DQY1 A0ACM8DQY1 PTHR11871:SF0 PROTEIN PHOSPHATASE PP2A REGULATORY SUBUNIT B PROTEIN PHOSPHATASE PP2A 55 KDA REGULATORY SUBUNIT molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytosol#GO:0005829 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 IXOSC|EnsemblGenome=LOC115320464|UniProtKB=A0ACM8FWE1 A0ACM8FWE1 l(1)G0196 PTHR12750:SF25 DIPHOSPHOINOSITOL PENTAKISPHOSPHATE KINASE INOSITOL HEXAKISPHOSPHATE AND DIPHOSPHOINOSITOL-PENTAKISPHOSPHATE KINASE phosphotransferase activity, phosphate group as acceptor#GO:0016776;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 nucleotide kinase#PC00172;kinase#PC00137 IXOSC|EnsemblGenome=LOC120836087|UniProtKB=A0ACM8G4Q5 A0ACM8G4Q5 LOC120836087 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042163|UniProtKB=A0ACM8E5Z2 A0ACM8E5Z2 LOC8042163 PTHR10681:SF180 THIOREDOXIN PEROXIDASE PEROXIREDOXIN-4 catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;oxidoreductase activity#GO:0016491 cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to oxidative stress#GO:0006979;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular process#GO:0009987;response to stress#GO:0006950 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;peroxidase#PC00180 IXOSC|EnsemblGenome=LOC8026298|UniProtKB=A0ACM8DW00 A0ACM8DW00 LOC8026298 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8032525|UniProtKB=A0ACM8DJI8 A0ACM8DJI8 LOC8032525 PTHR24364:SF18 LP06937P LP06937P membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120842537|UniProtKB=A0ACM8FVK7 A0ACM8FVK7 LOC120842537 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC120842799|UniProtKB=A0ACM8EUG8 A0ACM8EUG8 LOC120842799 PTHR11699:SF211 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1 aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC115332974|UniProtKB=A0ACM8G776 A0ACM8G776 LOC115332974 PTHR18976:SF34 APOLIPOPROTEIN LIPID-BINDING PROTEIN apolipoprotein#PC00052;transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8034050|UniProtKB=A0ACM8DIS5 A0ACM8DIS5 Gnpnat PTHR13355:SF11 GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE GLUCOSAMINE 6-PHOSPHATE N-ACETYLTRANSFERASE glucosamine 6-phosphate N-acetyltransferase activity#GO:0004343;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;catalytic activity#GO:0003824 acetyltransferase#PC00038;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835845|UniProtKB=A0ACM8FVD1 A0ACM8FVD1 LOC121835845 PTHR24248:SF187 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR OCTOPAMINE RECEPTOR BETA-2R signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;adrenergic receptor signaling pathway#GO:0071875;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8023083|UniProtKB=A0ACM8DGE4 A0ACM8DGE4 LOC8023083 PTHR43721:SF2 ELONGATION FACTOR TU-RELATED ELONGATION FACTOR TU, MITOCHONDRIAL translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;mitochondrial gene expression#GO:0140053;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC8030853|UniProtKB=A0ACM8DHL6 A0ACM8DHL6 LOC8030853 PTHR43861:SF1 TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC120838770|UniProtKB=A0ACM8ELJ6 A0ACM8ELJ6 LOC120838771 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;enzyme regulator activity#GO:0030234 positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell cycle#GO:0051726;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of programmed cell death#GO:0043069;positive regulation of protein ubiquitination#GO:0031398;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of apoptotic process#GO:0043066;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8050565|UniProtKB=A0ACM8F9Q9 A0ACM8F9Q9 PTHR10736:SF69 BESTROPHIN BESTROPHIN HOMOLOG monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267;chloride channel activity#GO:0005254;passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;chloride transmembrane transport#GO:1902476;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8025945|UniProtKB=A0ACM8DVW0 A0ACM8DVW0 LOC8025945 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139 microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8029154|UniProtKB=A0ACM8EXQ5 A0ACM8EXQ5 LOC8029154 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;small molecule binding#GO:0036094;catalytic activity#GO:0003824;binding#GO:0005488;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120843985|UniProtKB=A0ACM8EYG4 A0ACM8EYG4 LOC120843985 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115322227|UniProtKB=A0ACM8E1W8 A0ACM8E1W8 LOC115322227 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 IXOSC|EnsemblGenome=LOC8038910|UniProtKB=A0ACM8DTU3 A0ACM8DTU3 LOC8038910 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;cell communication#GO:0007154;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537;synaptic transmission, cholinergic#GO:0007271;monoatomic ion transmembrane transport#GO:0034220;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC121833583|UniProtKB=A0ACM8FLG9 A0ACM8FLG9 LOC121833583 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120851159|UniProtKB=A0ACM8FB96 A0ACM8FB96 LOC120851159 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8042991|UniProtKB=A0ACM8E024 A0ACM8E024 LOC8042991 PTHR10032:SF271 ZINC FINGER PROTEIN WITH KRAB AND SCAN DOMAINS RH12261P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;epithelium development#GO:0060429;regulation of nucleobase-containing compound metabolic process#GO:0019219;epithelial cell differentiation#GO:0030855;epidermal cell differentiation#GO:0009913;tissue development#GO:0009888;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;epidermis development#GO:0008544;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8029103|UniProtKB=A0ACM8EDK9 A0ACM8EDK9 LOC8029103 PTHR45623:SF14 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER CHD1 binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;protein binding#GO:0005515;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;DNA binding#GO:0003677;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular process#GO:0009987;cellular component organization#GO:0016043 nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115320125|UniProtKB=A0ACM8FXD4 A0ACM8FXD4 LOC115320125 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115322682|UniProtKB=A0ACM8FUZ3 A0ACM8FUZ3 LOC115322682 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120848769|UniProtKB=A0ACM8FMG0 A0ACM8FMG0 LOC120848769 PTHR16024:SF28 XK-RELATED PROTEIN XK-RELATED PROTEIN cellular component organization#GO:0016043;apoptotic process#GO:0006915;execution phase of apoptosis#GO:0097194;endocytosis#GO:0006897;lipid localization#GO:0010876;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;cellular process#GO:0009987;endomembrane system organization#GO:0010256;membrane invagination#GO:0010324;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;apoptotic cell clearance#GO:0043277;phagocytosis, engulfment#GO:0006911;programmed cell death#GO:0012501;cell death#GO:0008219;organophosphate ester transport#GO:0015748;lipid translocation#GO:0034204;plasma membrane phospholipid scrambling#GO:0017121;anatomical structure development#GO:0048856;localization#GO:0051179;macromolecule localization#GO:0033036;lipid transport#GO:0006869;biological regulation#GO:0065007;membrane organization#GO:0061024;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;phagocytosis#GO:0006909;transport#GO:0006810;developmental process#GO:0032502;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8024919|UniProtKB=A0ACM8DN15 A0ACM8DN15 LOC8024919 PTHR11056:SF0 HOMOGENTISATE 1,2-DIOXYGENASE HOMOGENTISATE 1,2-DIOXYGENASE catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;dioxygenase activity#GO:0051213;oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8033973|UniProtKB=A0ACM8F6N5 A0ACM8F6N5 LOC8033973 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC115319184|UniProtKB=A0ACM8FYU9 A0ACM8FYU9 LOC115319184 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8026394|UniProtKB=A0ACM8F491 A0ACM8F491 LOC8026394 PTHR10202:SF27 PRESENILIN PRESENILIN HOMOLOG catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 cell communication#GO:0007154;protein metabolic process#GO:0019538;proteolysis#GO:0006508;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219;metabolic process#GO:0008152;cell surface receptor signaling pathway#GO:0007166;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;membrane protein ectodomain proteolysis#GO:0006509;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;signal transduction#GO:0007165;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 catalytic complex#GO:1902494;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;membrane#GO:0016020 aspartic protease#PC00053;protease#PC00190 Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Notch signaling pathway#P00045>Presenilin#P01110 IXOSC|EnsemblGenome=LOC120844075|UniProtKB=A0ACM8EXR5 A0ACM8EXR5 LOC120844075 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC120840020|UniProtKB=A0ACM8EP71 A0ACM8EP71 LOC120840023 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120844391|UniProtKB=A0ACM8G1N1 A0ACM8G1N1 LOC120844391 PTHR45938:SF14 ACP24A4-RELATED IXOLARIS IXOSC|EnsemblGenome=LOC8040036|UniProtKB=A0ACM8E3B8 A0ACM8E3B8 PTHR11006:SF4 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 7 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;histone modifying activity#GO:0140993;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054 cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120843398|UniProtKB=A0ACM8EX45 A0ACM8EX45 LOC120843398 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033939|UniProtKB=A0ACM8E434 A0ACM8E434 LOC8033939 PTHR15335:SF7 PROTEIN TFG PROTEIN TFG vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8042297|UniProtKB=A0ACM8G7N3 A0ACM8G7N3 LOC8042297 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120841323|UniProtKB=A0ACM8FF84 A0ACM8FF84 LOC120841323 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115313876|UniProtKB=A0ACM8FPJ8 A0ACM8FPJ8 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8024563|UniProtKB=A0ACM8DIF1 A0ACM8DIF1 LOC8024563 PTHR11586:SF43 TRNA-AMINOACYLATION COFACTOR ARC1 FAMILY MEMBER TYROSINE--TRNA LIGASE, CYTOPLASMIC catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 translational protein#PC00263 IXOSC|EnsemblGenome=LOC8053432|UniProtKB=A0ACM8F9G4 A0ACM8F9G4 LOC8053432 PTHR11849:SF190 ETS ETS-DOMAIN PROTEIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115322796|UniProtKB=A0ACM8FT40 A0ACM8FT40 LOC121835032 PTHR22876:SF5 ZGC:101016 CHROMOSOME 9 OPEN READING FRAME 85 IXOSC|EnsemblGenome=LOC8028334|UniProtKB=A0ACM8DNL7 A0ACM8DNL7 LOC8028334 PTHR22807:SF30 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE(4447)-C(5))-METHYLTRANSFERASE catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;cellular process#GO:0009987;rRNA base methylation#GO:0070475;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;rRNA methylation#GO:0031167;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8052202|UniProtKB=A0ACM8DYV1 A0ACM8DYV1 mEFG1 PTHR43636:SF2 ELONGATION FACTOR G, MITOCHONDRIAL ELONGATION FACTOR G, MITOCHONDRIAL translation elongation factor activity#GO:0003746;ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;translational elongation#GO:0006414;biosynthetic process#GO:0009058;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC8033421|UniProtKB=A0ACM8DQH3 A0ACM8DQH3 LOC8033421 PTHR11390:SF21 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-ALPHA catalytic activity, acting on DNA#GO:0140097;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 cellular response to stress#GO:0033554;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;nucleus#GO:0005634;DNA helicase complex#GO:0033202;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121048330|UniProtKB=A0ACM8FJ28 A0ACM8FJ28 LOC121048330 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8051593|UniProtKB=A0ACM8DM13 A0ACM8DM13 LOC8051593 PTHR22911:SF6 ACYL-MALONYL CONDENSING ENZYME-RELATED RH69884P membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC120838825|UniProtKB=A0ACM8EKJ8 A0ACM8EKJ8 LOC120838825 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121834529|UniProtKB=A0ACM8FR69 A0ACM8FR69 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8036607|UniProtKB=A0ACM8EVQ5 A0ACM8EVQ5 LOC8036607 PTHR13030:SF15 NUDIX HYDROLASE NUDIX HYDROLASE DOMAIN-CONTAINING PROTEIN pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034021|UniProtKB=A0ACM8EQ90 A0ACM8EQ90 Zmynd8 PTHR46453:SF5 PROTEIN KINASE C-BINDING PROTEIN 1 MYND-TYPE ZINC FINGER-CONTAINING CHROMATIN READER ZMYND8 ISOFORM X1-RELATED transcription regulator activity#GO:0140110;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8033975|UniProtKB=A0ACM8E2Q5 A0ACM8E2Q5 LOC8033975 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115330523|UniProtKB=A0ACM8EBB5 A0ACM8EBB5 LOC115330523 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8043758|UniProtKB=A0ACM8DGX3 A0ACM8DGX3 LOC8043758 PTHR13593:SF113 FAMILY NOT NAMED PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C X DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115322242|UniProtKB=A0ACM8EZN2 A0ACM8EZN2 LOC115322242 PTHR24252:SF35 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 5-RELATED serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115309024|UniProtKB=A0ACM8DN94 A0ACM8DN94 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320768|UniProtKB=A0ACM8FES0 A0ACM8FES0 LOC115320768 PTHR34105:SF1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 PROLINE-, GLUTAMIC ACID- AND LEUCINE-RICH PROTEIN 1 cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8031558|UniProtKB=A0ACM8E4X5 A0ACM8E4X5 LOC8031558 PTHR23245:SF44 TRNA METHYLTRANSFERASE TRNA (GUANINE(37)-N(1))-METHYLTRANSFERASE methyltransferase activity#GO:0008168;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098;tRNA methyltransferase activity#GO:0008175 mitochondrial RNA modification#GO:1900864;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;tRNA methylation#GO:0030488;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC121048334|UniProtKB=A0ACM8FHX9 A0ACM8FHX9 LOC121048334 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115312499|UniProtKB=A0ACM8EUE3 A0ACM8EUE3 LOC115312499 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318116|UniProtKB=A0ACM8F8Z2 A0ACM8F8Z2 LOC115318116 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC chromatin binding#GO:0003682;binding#GO:0005488 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122 protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519;intracellular protein-containing complex#GO:0140535;PRC1 complex#GO:0035102;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8039789|UniProtKB=A0ACM8EV23 A0ACM8EV23 LOC8039789 PTHR45938:SF14 ACP24A4-RELATED IXOLARIS IXOSC|EnsemblGenome=LOC8041238|UniProtKB=A0ACM8DKN5 A0ACM8DKN5 LOC8041238 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741;transferase activity#GO:0016740;catalytic activity#GO:0003824 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8032589|UniProtKB=A0ACM8DZT9 A0ACM8DZT9 Usp14 PTHR43982:SF1 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 14 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;protein-containing complex binding#GO:0044877;hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;binding#GO:0005488 negative regulation of response to stimulus#GO:0048585;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;regulation of catabolic process#GO:0009894;regulation of response to stress#GO:0080134;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of protein metabolic process#GO:0051248;negative regulation of proteasomal protein catabolic process#GO:1901799;negative regulation of metabolic process#GO:0009892;regulation of ERAD pathway#GO:1904292;negative regulation of biological process#GO:0048519;regulation of response to endoplasmic reticulum stress#GO:1905897;regulation of biological process#GO:0050789;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895;regulation of cellular response to stress#GO:0080135 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8040138|UniProtKB=A0ACM8F6D0 A0ACM8F6D0 LOC8040138 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8040364|UniProtKB=A0ACM8FAH5 A0ACM8FAH5 LOC8040364 PTHR11616:SF334 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1 monoatomic cation transmembrane transporter activity#GO:0008324;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;carboxylic acid transmembrane transporter activity#GO:0046943;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 glycine transport#GO:0015816;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;import into cell#GO:0098657;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC115325129|UniProtKB=A0ACM8EZ15 A0ACM8EZ15 LOC115325129 PTHR30543:SF21 CHROMATE REDUCTASE NAD(P)H-DEPENDENT FMN REDUCTASE LOT6 oxidoreductase activity#GO:0016491;NAD(P)H dehydrogenase (quinone) activity#GO:0003955;oxidoreductase activity, acting on NAD(P)H#GO:0016651;oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor#GO:0016655;catalytic activity#GO:0003824 response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to oxidative stress#GO:0034599;cellular response to chemical stimulus#GO:0070887;cellular response to stress#GO:0033554;cellular response to chemical stress#GO:0062197;response to oxidative stress#GO:0006979 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115317645|UniProtKB=A0ACM8F5F0 A0ACM8F5F0 LOC120848101 PTHR23077:SF202 AAA-FAMILY ATPASE TRANSITIONAL ENDOPLASMIC RETICULUM ATPASE TER94 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;polyubiquitin modification-dependent protein binding#GO:0031593;ribonucleoside triphosphate phosphatase activity#GO:0017111;ATP-dependent activity#GO:0140657;binding#GO:0005488;modification-dependent protein binding#GO:0140030;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515 response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;cytoskeleton organization#GO:0007010;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;autophagy#GO:0006914;establishment of protein localization#GO:0045184;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;mitotic spindle organization#GO:0007052;response to stimulus#GO:0050896;cellular component organization#GO:0016043;cell cycle process#GO:0022402;cellular component disassembly#GO:0022411;organelle disassembly#GO:1903008;protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;macroautophagy#GO:0016236;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;spindle organization#GO:0007051;ubiquitin-dependent protein catabolic process#GO:0006511;mitotic cell cycle process#GO:1903047;intracellular protein localization#GO:0008104;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;autophagosome maturation#GO:0097352;transport#GO:0006810;catabolic process#GO:0009056;mitotic cell cycle#GO:0000278;protein-containing complex disassembly#GO:0032984;primary metabolic process#GO:0044238;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;cytosol#GO:0005829;membrane#GO:0016020;nucleus#GO:0005634;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;membrane protein complex#GO:0098796;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121838009|UniProtKB=A0ACM8G670 A0ACM8G670 LOC121838009 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038374|UniProtKB=A0ACM8DK73 A0ACM8DK73 CCT8 PTHR11353:SF19 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT THETA ISOFORM X1 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;chaperonin-containing T-complex#GO:0005832;protein folding chaperone complex#GO:0101031 chaperonin#PC00073 IXOSC|EnsemblGenome=LOC8025930|UniProtKB=A0ACM8FAQ2 A0ACM8FAQ2 LOC8025930 PTHR23110:SF118 BTB DOMAIN TRANSCRIPTION FACTOR PROTEIN TRAMTRACK, ALPHA ISOFORM regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8024453|UniProtKB=A0ACM8E1X6 A0ACM8E1X6 Gdh PTHR11606:SF13 GLUTAMATE DEHYDROGENASE GLUTAMATE DEHYDROGENASE 1, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 Glutamine glutamate conversion#P02745>Glutamate Dehydrogenase#P02967 IXOSC|EnsemblGenome=LOC115332115|UniProtKB=A0ACM8ED25 A0ACM8ED25 LOC115332115 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835823|UniProtKB=A0ACM8FWQ4 A0ACM8FWQ4 LOC121835823 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313867|UniProtKB=A0ACM8ESU3 A0ACM8ESU3 LOC121838339 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024116|UniProtKB=A0ACM8G2K0 A0ACM8G2K0 LOC8024116 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115330291|UniProtKB=A0ACM8EBK5 A0ACM8EBK5 LOC115330291 PTHR22967:SF105 SERINE/THREONINE PROTEIN KINASE CYCLIN-G-ASSOCIATED KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8051683|UniProtKB=A0ACM8DL92 A0ACM8DL92 LOC8051683 PTHR20917:SF1 PNAS-RELATED CALCIUM LOAD-ACTIVATED CALCIUM CHANNEL calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262 chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8041789|UniProtKB=A0ACM8FVK1 A0ACM8FVK1 LOC8041789 PTHR21646:SF14 UBIQUITIN CARBOXYL-TERMINAL HYDROLASE UBIQUITINYL HYDROLASE 1 cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783;deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787 regulation of protein stability#GO:0031647;regulation of biological quality#GO:0065008;biological regulation#GO:0065007 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115318774|UniProtKB=A0ACM8FXS9 A0ACM8FXS9 LOC115318774 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8033380|UniProtKB=A0ACM8E1G4 A0ACM8E1G4 LOC8033380 PTHR23308:SF66 NUCLEAR INHIBITOR OF PROTEIN PHOSPHATASE-1 KANADAPTIN molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120850655|UniProtKB=A0ACM8FC24 A0ACM8FC24 LOC120850655 PTHR46393:SF7 SUSHI DOMAIN-CONTAINING PROTEIN C3_C5 CONVERTASE IXOSC|EnsemblGenome=LOC115332141|UniProtKB=A0ACM8EDU9 A0ACM8EDU9 Dph2 PTHR10762:SF2 DIPHTHAMIDE BIOSYNTHESIS PROTEIN 2-(3-AMINO-3-CARBOXYPROPYL)HISTIDINE SYNTHASE SUBUNIT 2 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;metabolic process#GO:0008152;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC8036103|UniProtKB=A0ACM8DMZ9 A0ACM8DMZ9 LOC8036103 PTHR23255:SF100 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transforming growth factor beta receptor activity#GO:0005024;transferase activity#GO:0016740;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089 cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;cellular response to BMP stimulus#GO:0071773;response to BMP#GO:0071772;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944 serine/threonine protein kinase receptor#PC00205 BMP/activin signaling pathway-drosophila#P06211>TGFbetaR II#P06255;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;MYO signaling pathway#P06215>WIT#P06316;GBB signaling pathway#P06214>WIT#P06306 IXOSC|EnsemblGenome=LOC120851185|UniProtKB=A0ACM8FBN0 A0ACM8FBN0 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 IXOSC|EnsemblGenome=LOC115311867|UniProtKB=A0ACM8DRM3 A0ACM8DRM3 LOC115311867 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC121048573|UniProtKB=A0ACM8FHD6 A0ACM8FHD6 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314770|UniProtKB=A0ACM8DUH3 A0ACM8DUH3 LOC115314770 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031192|UniProtKB=A0ACM8DWR8 A0ACM8DWR8 LOC8031192 PTHR16089:SF28 REST COREPRESSOR COREST PROTEIN-RELATED REST COREPRESSOR transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714 negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8030708|UniProtKB=A0ACM8DHF8 A0ACM8DHF8 LOC8030708 PTHR23430:SF50 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 negative regulation of cellular process#GO:0048523;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120845797|UniProtKB=A0ACM8F0S2 A0ACM8F0S2 LOC120845797 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8034797|UniProtKB=A0ACM8EKQ8 A0ACM8EKQ8 LOC8034797 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC115324115|UniProtKB=A0ACM8FRP0 A0ACM8FRP0 LOC115324115 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8024131|UniProtKB=A0ACM8G642 A0ACM8G642 LOC8024131 PTHR16484:SF17 PARTITIONING DEFECTIVE 3 RELATED BAZOOKA, ISOFORM B ion binding#GO:0043167;phosphatidylinositol binding#GO:0035091;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;cellular component organization#GO:0016043;establishment of cell polarity#GO:0030010;establishment or maintenance of cell polarity#GO:0007163;establishment or maintenance of apical/basal cell polarity#GO:0035088;cell adhesion#GO:0007155;establishment or maintenance of bipolar cell polarity#GO:0061245;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;microtubule cytoskeleton organization#GO:0000226 apical plasma membrane#GO:0016324;membrane#GO:0016020;cell-cell junction#GO:0005911;cell cortex#GO:0005938;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;apical junction complex#GO:0043296;apical part of cell#GO:0045177;cell junction#GO:0030054;adherens junction#GO:0005912;intracellular anatomical structure#GO:0005622;anchoring junction#GO:0070161 IXOSC|EnsemblGenome=LOC120848771|UniProtKB=A0ACM8F6F4 A0ACM8F6F4 LOC120848771 PTHR13902:SF177 SERINE/THREONINE-PROTEIN KINASE WNK WITH NO LYSINE -RELATED SERINE_THREONINE-PROTEIN KINASE WNK channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;potassium channel regulator activity#GO:0015459;transporter regulator activity#GO:0141108;protein serine/threonine kinase activity#GO:0004674;molecular function regulator activity#GO:0098772;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of monoatomic ion transport#GO:0043269;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;regulation of monoatomic ion transmembrane transport#GO:0034765;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of transport#GO:0051050;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of monoatomic cation transmembrane transport#GO:1904062;chemical homeostasis#GO:0048878;regulation of cellular process#GO:0050794;regulation of metal ion transport#GO:0010959;negative regulation of transport#GO:0051051;response to stimulus#GO:0050896;signaling#GO:0023052;homeostatic process#GO:0042592;regulation of transmembrane transport#GO:0034762;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121047065|UniProtKB=A0ACM8FU93 A0ACM8FU93 LOC121047065 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179;transport#GO:0006810;lipid localization#GO:0010876;macromolecule localization#GO:0033036 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120837828|UniProtKB=A0ACM8EJE1 A0ACM8EJE1 LOC120837828 PTHR10041:SF11 COLIPASE SUBFAMILY NOT NAMED protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120846561|UniProtKB=A0ACM8F2Q2 A0ACM8F2Q2 PTHR46169:SF15 DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A DNA REPLICATION-RELATED ELEMENT FACTOR, ISOFORM A regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8051191|UniProtKB=A0ACM8DLW5 A0ACM8DLW5 Not10 PTHR12979:SF5 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 10 negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of translation#GO:0017148;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of protein metabolic process#GO:0051248;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;CCR4-NOT complex#GO:0030014 IXOSC|EnsemblGenome=LOC8035216|UniProtKB=A0ACM8DVN3 A0ACM8DVN3 LOC8035216 PTHR12619:SF5 RFX TRANSCRIPTION FACTOR FAMILY RFX, ISOFORM H sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8033618|UniProtKB=A0ACM8ECQ2 A0ACM8ECQ2 LOC8033618 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8023741|UniProtKB=A0ACM8DSQ1 A0ACM8DSQ1 Ttc19 PTHR13143:SF6 TETRATRICOPEPTIDE REPEAT PROTEIN 19 TETRATRICOPEPTIDE REPEAT PROTEIN 19, MITOCHONDRIAL cytochrome complex assembly#GO:0017004;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex III assembly#GO:0034551;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115314153|UniProtKB=A0ACM8ELB6 A0ACM8ELB6 LOC115314153 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120838786|UniProtKB=A0ACM8EJY4 A0ACM8EJY4 LOC120838786 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850408|UniProtKB=A0ACM8F9S9 A0ACM8F9S9 LOC120850408 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052661|UniProtKB=A0ACM8DZ07 A0ACM8DZ07 LOC8052661 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 IXOSC|EnsemblGenome=ISCI010050|UniProtKB=B7Q1Q9 B7Q1Q9 IscW_ISCW010050 PTHR10966:SF0 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 2 binding#GO:0005488;transcription factor binding#GO:0008134;protein binding#GO:0005515 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component assembly#GO:0022607;gene expression#GO:0010467;protein-DNA complex assembly#GO:0065004;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein-containing complex assembly#GO:0065003;DNA-templated transcription initiation#GO:0006352;RNA biosynthetic process#GO:0032774;RNA polymerase II preinitiation complex assembly#GO:0051123;DNA-templated transcription#GO:0006351 membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259 General transcription regulation#P00023>TFIIA complex#P00662;Transcription regulation by bZIP transcription factor#P00055>TFIIA complex#P01390 IXOSC|EnsemblGenome=LOC8052981|UniProtKB=A0ACM8DWC9 A0ACM8DWC9 LOC8052981 PTHR22981:SF85 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED 3-HYDROXYISOBUTYRATE DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120842248|UniProtKB=A0ACM8ETC6 A0ACM8ETC6 LOC120842248 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053545|UniProtKB=A0ACM8EBS6 A0ACM8EBS6 rad50 PTHR18867:SF12 RAD50 DNA REPAIR PROTEIN RAD50 single-stranded DNA binding#GO:0003697;binding#GO:0005488;nucleic acid binding#GO:0003676;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;telomeric repeat DNA binding#GO:0042162;DNA binding#GO:0003677 telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;RNA-templated DNA biosynthetic process#GO:0006278;DNA repair#GO:0006281;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;telomere organization#GO:0032200;sexual reproduction#GO:0019953;mitotic recombination#GO:0006312;reproductive process#GO:0022414;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;chromosome organization involved in meiotic cell cycle#GO:0070192;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;telomere maintenance via telomere lengthening#GO:0010833;telomere maintenance via telomerase#GO:0007004;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897;response to stress#GO:0006950;organelle organization#GO:0006996;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;chromosome#GO:0005694;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;condensed nuclear chromosome#GO:0000794;condensed chromosome#GO:0000793;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120840907|UniProtKB=A0ACM8ERH9 A0ACM8ERH9 LOC120840907 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115308811|UniProtKB=A0ACM8DMZ1 A0ACM8DMZ1 LOC115308811 PTHR10151:SF131 ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE GLYCEROPHOSPHOCHOLINE CHOLINEPHOSPHODIESTERASE catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121837968|UniProtKB=A0ACM8G623 A0ACM8G623 LOC121837968 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121833049|UniProtKB=A0ACM8FJB1 A0ACM8FJB1 LOC121833049 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023136|UniProtKB=A0ACM8E750 A0ACM8E750 INTS7 PTHR13322:SF2 C1ORF73 PROTEIN INTEGRATOR COMPLEX SUBUNIT 7 macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;nucleobase-containing compound catabolic process#GO:0034655;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription initiation#GO:0006352;catabolic process#GO:0009056;DNA-templated transcription#GO:0006351;snRNA 3'-end processing#GO:0034472;RNA biosynthetic process#GO:0032774 integrator complex#GO:0032039;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121048203|UniProtKB=A0ACM8G2T3 A0ACM8G2T3 LOC121048203 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120837745|UniProtKB=A0ACM8G486 A0ACM8G486 LOC120837745 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046213|UniProtKB=A0ACM8FDE8 A0ACM8FDE8 LOC121046213 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842657|UniProtKB=A0ACM8EU40 A0ACM8EU40 LOC120842657 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8032039|UniProtKB=A0ACM8DJ24 A0ACM8DJ24 LOC8032039 PTHR11008:SF9 PROTEIN TAKEOUT-LIKE PROTEIN FI04421P IXOSC|EnsemblGenome=LOC8026656|UniProtKB=A0ACM8FNP6 A0ACM8FNP6 PTHR10332:SF80 EQUILIBRATIVE NUCLEOSIDE TRANSPORTER EQUILIBRATIVE NUCLEOSIDE TRANSPORTER 2, ISOFORM A transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleobase-containing compound transmembrane transporter activity#GO:0015932;nucleoside transmembrane transporter activity#GO:0005337 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8038748|UniProtKB=A0ACM8FMD3 A0ACM8FMD3 Pka-R2 PTHR11635:SF152 CAMP-DEPENDENT PROTEIN KINASE REGULATORY CHAIN CAMP-DEPENDENT PROTEIN KINASE TYPE I REGULATORY SUBUNIT-RELATED cell communication#GO:0007154;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 kinase modulator#PC00140;protein-binding activity modulator#PC00095 Cell cycle#P00013>Protein kinase subunit#P00482;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Hedgehog signaling pathway#P00025>PKA#P00682;Transcription regulation by bZIP transcription factor#P00055>PKA#P01384;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;GABA-B receptor II signaling#P05731>PKA#P05752;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Endothelin signaling pathway#P00019>PKA#P00570;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Enkephalin release#P05913>PKA#P05972;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035 IXOSC|EnsemblGenome=LOC8053956|UniProtKB=A0ACM8E9L0 A0ACM8E9L0 LOC8053956 PTHR23057:SF0 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 JUXTAPOSED WITH ANOTHER ZINC FINGER PROTEIN 1 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115320726|UniProtKB=A0ACM8E1G7 A0ACM8E1G7 LOC115320726 PTHR15666:SF1 COMM DOMAIN CONTAINING PROTEIN 5 COMM DOMAIN-CONTAINING PROTEIN 5 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC121046765|UniProtKB=A0ACM8G2S9 A0ACM8G2S9 LOC121046765 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8036310|UniProtKB=A0ACM8DHC7 A0ACM8DHC7 LOC8036310 PTHR12789:SF0 DENSITY-REGULATED PROTEIN HOMOLOG DENSITY-REGULATED PROTEIN binding#GO:0005488;ribonucleoprotein complex binding#GO:0043021;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877 translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8031261|UniProtKB=A0ACM8DI29 A0ACM8DI29 LOC8031261 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8037779|UniProtKB=A0ACM8DI95 A0ACM8DI95 LOC8037779 PTHR46021:SF2 ARF-GAP WITH DUAL PH DOMAIN-CONTAINING PROTEIN 1-LIKE PROTEIN CENTAURIN ALPHA phosphatidylinositol phosphate binding#GO:1901981;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;phospholipid binding#GO:0005543;enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;lipid binding#GO:0008289;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8029434|UniProtKB=A0ACM8EE20 A0ACM8EE20 LOC8029434 PTHR15256:SF6 INTEGRAL MEMBRANE PROTEIN DGCR2/IDD INTEGRAL MEMBRANE PROTEIN DGCR2_IDD cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8029240|UniProtKB=A0ACM8E6V8 A0ACM8E6V8 LOC8029240 PTHR14136:SF17 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 BTB_POZ DOMAIN-CONTAINING PROTEIN KCTD9 IXOSC|EnsemblGenome=LOC115331642|UniProtKB=A0ACM8ECH4 A0ACM8ECH4 LOC115331642 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC115312841|UniProtKB=A0ACM8DSJ4 A0ACM8DSJ4 LOC115312841 PTHR47103:SF6 DNA-BINDING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314655|UniProtKB=A0ACM8EMT6 A0ACM8EMT6 LOC115314655 PTHR43816:SF1 NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;glycosyltransferase activity#GO:0016757 nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115320721|UniProtKB=A0ACM8E115 A0ACM8E115 Vha14-1 PTHR13861:SF2 VACUOLAR ATP SYNTHASE SUBUNIT F V-TYPE PROTON ATPASE SUBUNIT F membrane#GO:0016020;cellular anatomical structure#GO:0110165 ATP synthase#PC00002;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120838533|UniProtKB=A0ACM8FJQ1 A0ACM8FJQ1 LOC120838533 PTHR19282:SF570 TETRASPANIN TETRASPANIN TSPA-RELATED scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8025471|UniProtKB=A0ACM8DJ93 A0ACM8DJ93 LOC8025471 PTHR43884:SF47 ACYL-COA DEHYDROGENASE ISOVALERYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8050754|UniProtKB=A0ACM8DLT9 A0ACM8DLT9 MSBP PTHR10281:SF106 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED IP06960P-RELATED membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115308212|UniProtKB=A0ACM8FGM1 A0ACM8FGM1 LOC115308212 PTHR10579:SF178 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-LIKE ion channel#PC00133 IXOSC|EnsemblGenome=LOC8051437|UniProtKB=A0ACM8DS44 A0ACM8DS44 LOC8051437 PTHR23113:SF374 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS-GEF DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of signaling#GO:0023051;Ras protein signal transduction#GO:0007265;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8023548|UniProtKB=A0ACM8DSJ8 A0ACM8DSJ8 LOC8023548 PTHR21812:SF1 INO80 COMPLEX SUBUNIT E INO80 COMPLEX SUBUNIT E regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;regulation of DNA replication#GO:0006275;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;cellular component organization#GO:0016043;regulation of DNA metabolic process#GO:0051052;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;chromatin remodeling#GO:0006338 nucleus#GO:0005634;chromatin#GO:0000785;membrane-enclosed lumen#GO:0031974;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;Ino80 complex#GO:0031011;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346 IXOSC|EnsemblGenome=LOC115318253|UniProtKB=A0ACM8EHA2 A0ACM8EHA2 LOC115318253 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314300|UniProtKB=A0ACM8DU50 A0ACM8DU50 LOC115314300 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8036646|UniProtKB=A0ACM8G3W0 A0ACM8G3W0 LOC8036646 PTHR11351:SF21 ACYL-COA DESATURASE GH07782P-RELATED ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506 small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;oxoacid metabolic process#GO:0043436;lipid biosynthetic process#GO:0008610;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 IXOSC|EnsemblGenome=LOC8024125|UniProtKB=A0ACM8DHZ1 A0ACM8DHZ1 LOC8024125 PTHR30615:SF8 UNCHARACTERIZED PROTEIN YJBQ-RELATED UPF0047 PROTEIN C4A8.02C IXOSC|EnsemblGenome=LOC121837649|UniProtKB=A0ACM8G4F1 A0ACM8G4F1 LOC121837649 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115315072|UniProtKB=A0ACM8EQL4 A0ACM8EQL4 LOC115315072 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8023474|UniProtKB=A0ACM8DPS7 A0ACM8DPS7 LOC8023474 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120836345|UniProtKB=A0ACM8FBA5 A0ACM8FBA5 LOC120836345 PTHR31400:SF1 GUANYLYL CYCLASE DOMAIN CONTAINING PROTEIN 1 GUCD1 PROTEIN GUCD1 guanylate cyclase#PC00114 IXOSC|EnsemblGenome=LOC115320255|UniProtKB=A0ACM8E006 A0ACM8E006 LOC115320255 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332859|UniProtKB=A0ACM8G018 A0ACM8G018 LOC115332859 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;transporter activity#GO:0005215;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC121836402|UniProtKB=A0ACM8FY24 A0ACM8FY24 LOC121836402 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115331873|UniProtKB=A0ACM8EDY7 A0ACM8EDY7 LOC115331873 PTHR12243:SF60 MADF DOMAIN TRANSCRIPTION FACTOR MADF DOMAIN-CONTAINING PROTEIN regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121833939|UniProtKB=A0ACM8FNE1 A0ACM8FNE1 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051426|UniProtKB=A0ACM8DPP4 A0ACM8DPP4 LOC8051426 PTHR31711:SF1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 ARGININE AND GLUTAMATE-RICH PROTEIN 1 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC115319841|UniProtKB=A0ACM8FAC7 A0ACM8FAC7 LOC115319841 PTHR11412:SF166 MACROGLOBULIN / COMPLEMENT OPHIOPHAGUS VENOM FACTOR-LIKE receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;signaling receptor binding#GO:0005102;cytokine receptor binding#GO:0005126;binding#GO:0005488;cytokine activity#GO:0005125;chemokine receptor binding#GO:0042379;protein binding#GO:0005515;molecular function activator activity#GO:0140677 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 extracellular region#GO:0005576;extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8041733|UniProtKB=A0ACM8E550 A0ACM8E550 LOC8041733 PTHR47086:SF4 BTB DOMAIN-CONTAINING PROTEIN BTB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320330|UniProtKB=A0ACM8FLN8 A0ACM8FLN8 LOC121833527 PTHR23098:SF16 AGAP001331-PA-RELATED GT1 DOMAIN-CONTAINING PROTEIN membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120839975|UniProtKB=A0ACM8G4U0 A0ACM8G4U0 LOC120839975 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;nucleobase-containing compound metabolic process#GO:0006139;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637 intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8028232|UniProtKB=A0ACM8DJL7 A0ACM8DJL7 LOC8028232 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8034826|UniProtKB=A0ACM8E657 A0ACM8E657 LOC8034826 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8024639|UniProtKB=A0ACM8E8A6 A0ACM8E8A6 LOC8024639 PTHR11008:SF9 PROTEIN TAKEOUT-LIKE PROTEIN FI04421P IXOSC|EnsemblGenome=LOC8030275|UniProtKB=A0ACM8DZQ7 A0ACM8DZQ7 LOC8030275 PTHR15141:SF76 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 3 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;transcription by RNA polymerase II#GO:0006366;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;DNA-templated transcription elongation#GO:0006354;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8043607|UniProtKB=A0ACM8E8K8 A0ACM8E8K8 LOC8043607 PTHR45627:SF30 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 3 lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849 organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;signal transduction#GO:0007165;ribose phosphate biosynthetic process#GO:0046390 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 adenylate cyclase#PC00043 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719;Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 IXOSC|EnsemblGenome=LOC115321657|UniProtKB=A0ACM8EYA2 A0ACM8EYA2 LOC115321657 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032400|UniProtKB=A0ACM8DZZ2 A0ACM8DZZ2 boca PTHR17600:SF2 MESODERM DEVELOPMENT CANDIDATE 2 LRP CHAPERONE MESD IXOSC|EnsemblGenome=LOC8040125|UniProtKB=A0ACM8DKI0 A0ACM8DKI0 LOC8040125 PTHR16140:SF0 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 NON-STRUCTURAL MAINTENANCE OF CHROMOSOMES ELEMENT 4 macromolecule metabolic process#GO:0043170;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121837913|UniProtKB=A0ACM8G5N6 A0ACM8G5N6 LOC121837913 PTHR10030:SF37 ALPHA-L-FUCOSIDASE TISSUE ALPHA-L-FUCOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;carbohydrate metabolic process#GO:0005975;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115321342|UniProtKB=A0ACM8EZZ7 A0ACM8EZZ7 LOC115321342 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8033768|UniProtKB=A0ACM8G2H3 A0ACM8G2H3 LOC8033768 PTHR11893:SF40 INNEXIN INNEXIN SHAKING-B passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;wide pore channel activity#GO:0022829;channel activity#GO:0015267 cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;anchoring junction#GO:0070161;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 gap junction#PC00105 IXOSC|EnsemblGenome=LOC8031320|UniProtKB=A0ACM8DI41 A0ACM8DI41 LOC8031320 PTHR46680:SF3 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR CACTUS transcription factor binding#GO:0008134;binding#GO:0005488;molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297 negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;regulation of canonical NF-kappaB signal transduction#GO:0043122 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Toll pathway-drosophila#P06217>CACT#P06342 IXOSC|EnsemblGenome=LOC115318283|UniProtKB=A0ACM8ER66 A0ACM8ER66 LOC115318283 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120835986|UniProtKB=A0ACM8EXR9 A0ACM8EXR9 LOC120835986 PTHR11360:SF251 MONOCARBOXYLATE TRANSPORTER KARMOISIN, ISOFORM B monocarboxylic acid transmembrane transporter activity#GO:0008028;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC121046095|UniProtKB=A0ACM8FVP9 A0ACM8FVP9 LOC121046095 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8027667|UniProtKB=A0ACM8EJ18 A0ACM8EJ18 LOC8027667 PTHR10974:SF77 FI08016P-RELATED FI08016P-RELATED IXOSC|EnsemblGenome=LOC8031829|UniProtKB=A0ACM8DIT1 A0ACM8DIT1 LOC8031829 PTHR11472:SF41 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER ATP-DEPENDENT DNA HELICASE DDX11-RELATED ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853 cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;cell cycle process#GO:0022402;sister chromatid cohesion#GO:0007062;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA helicase#PC00011;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115323582|UniProtKB=A0ACM8E333 A0ACM8E333 LOC115323582 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8053584|UniProtKB=A0ACM8ECE0 A0ACM8ECE0 LOC8053584 PTHR24068:SF33 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120838743|UniProtKB=A0ACM8EL69 A0ACM8EL69 LOC120838743 PTHR10221:SF22 TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6 TAF6-LIKE RNA POLYMERASE II P300_CBP-ASSOCIATED FACTOR-ASSOCIATED FACTOR 65 KDA SUBUNIT 6L protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA polymerase II preinitiation complex assembly#GO:0051123;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;transcription by RNA polymerase II#GO:0006366;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;DNA-templated transcription initiation#GO:0006352;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;cellular component biogenesis#GO:0044085;protein-DNA complex assembly#GO:0065004;gene expression#GO:0010467;cellular component assembly#GO:0022607 chromosome#GO:0005694;nuclear DNA-directed RNA polymerase complex#GO:0055029;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;RNA polymerase II, holoenzyme#GO:0016591;SAGA-type complex#GO:0070461;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;peptidase complex#GO:1905368;transferase complex#GO:1990234;membraneless organelle#GO:0043228;intracellular protein-containing complex#GO:0140535;transcription regulator complex#GO:0005667;organelle lumen#GO:0043233;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;acetyltransferase complex#GO:1902493;SAGA complex#GO:0000124;chromatin#GO:0000785;protein-containing complex#GO:0032991;transcription factor TFIID complex#GO:0005669;intracellular membraneless organelle#GO:0043232;nuclear protein-containing complex#GO:0140513;histone acetyltransferase complex#GO:0000123 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC115313891|UniProtKB=A0ACM8EXV9 A0ACM8EXV9 LOC115313891 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115317510|UniProtKB=A0ACM8ENS0 A0ACM8ENS0 LOC115317510 PTHR11547:SF38 ARGININE OR CREATINE KINASE ARGININE KINASE 1-RELATED kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 amino acid kinase#PC00045;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8028707|UniProtKB=A0ACM8EAL4 A0ACM8EAL4 RfC38 PTHR11669:SF1 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 3 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity#GO:0140657 response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;replication fork#GO:0005657;nucleus#GO:0005634;chromosome#GO:0005694 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 IXOSC|EnsemblGenome=LOC121835761|UniProtKB=A0ACM8FVR4 A0ACM8FVR4 LOC121835761 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8030938|UniProtKB=A0ACM8FMN8 A0ACM8FMN8 LOC8030938 PTHR43038:SF3 ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 ABC TRANSPORTER G FAMILY MEMBER 23 ISOFORM X1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120850023|UniProtKB=A0ACM8F911 A0ACM8F911 LOC120850023 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034154|UniProtKB=A0ACM8DJ01 A0ACM8DJ01 LOC8034154 PTHR43681:SF3 TRANSMEMBRANE GTPASE FZO SARCALUMENIN monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810 protein-binding activity modulator#PC00095;G-protein#PC00020 IXOSC|EnsemblGenome=LOC8042322|UniProtKB=A0ACM8E5T7 A0ACM8E5T7 LOC8042322 PTHR12939:SF10 SARCOGLYCAN SARCOGLYCAN COMPLEX SUBUNIT PROTEIN cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC115322027|UniProtKB=A0ACM8EFX0 A0ACM8EFX0 LOC115322027 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8023940|UniProtKB=A0ACM8ENK1 A0ACM8ENK1 LOC8023940 PTHR12353:SF31 DISKS LARGE-ASSOCIATED PROTEIN DAP SAP90/PSD-95-ASSOCIATED PROTEIN LD44824P regulation of cell communication#GO:0010646;biological regulation#GO:0065007;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789 organelle#GO:0043226;postsynaptic specialization#GO:0099572;cell junction#GO:0030054;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;postsynapse#GO:0098794 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8042699|UniProtKB=A0ACM8DKY4 A0ACM8DKY4 LOC8042699 PTHR24253:SF153 TRANSMEMBRANE PROTEASE SERINE PEPTIDASE S1 DOMAIN-CONTAINING PROTEIN protein modifying enzyme#PC00260;protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8050980|UniProtKB=A0ACM8E6Q9 A0ACM8E6Q9 LOC8050980 PTHR12758:SF25 APOPTOSIS INHIBITOR 5-RELATED APOPTOSIS INHIBITOR 5 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of biological process#GO:0050789;negative regulation of programmed cell death#GO:0043069 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120839161|UniProtKB=A0ACM8ELM0 A0ACM8ELM0 LOC120839161 PTHR46880:SF5 RAS-ASSOCIATING DOMAIN-CONTAINING PROTEIN HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043540|UniProtKB=A0ACM8DGM9 A0ACM8DGM9 Bet1 PTHR12791:SF64 GOLGI SNARE BET1-RELATED BET1 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 vesicle fusion#GO:0006906;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;membrane fusion#GO:0061025;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 membrane protein complex#GO:0098796;membrane#GO:0016020;SNARE complex#GO:0031201;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 SNARE protein#PC00034 IXOSC|EnsemblGenome=LOC121047034|UniProtKB=A0ACM8FGA2 A0ACM8FGA2 LOC121047034 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8051828|UniProtKB=A0ACM8DLM8 A0ACM8DLM8 LOC8051828 PTHR13410:SF9 PROTEIN PBDC1 PROTEIN PBDC1 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;protein folding#GO:0006457;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 IXOSC|EnsemblGenome=LOC120842227|UniProtKB=A0ACM8ETA8 A0ACM8ETA8 LOC120842227 PTHR10485:SF0 MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM-17 AT05822P-RELATED transmembrane protein transporter activity#GO:0008320;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane transport#GO:0071806;mitochondrial protein import pathway#GO:7770058;protein import into mitochondrial matrix#GO:0030150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;transmembrane transport#GO:0055085;protein transport#GO:0015031;mitochondrial transmembrane transport#GO:1990542;mitochondrial transport#GO:0006839;protein localization to organelle#GO:0033365;protein localization to mitochondrion#GO:0070585 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800 transporter#PC00227 IXOSC|EnsemblGenome=LOC8037595|UniProtKB=A0ACM8F966 A0ACM8F966 LOC8037595 PTHR11567:SF211 ACID PHOSPHATASE-RELATED ACID PHOSPHATASE catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8023177|UniProtKB=A0ACM8EEJ9 A0ACM8EEJ9 LOC8023177 PTHR14614:SF167 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN HISTONE-ARGININE METHYLTRANSFERASE METTL23 histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;protein methyltransferase activity#GO:0008276 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;epigenetic regulation of gene expression#GO:0040029;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;biological regulation#GO:0065007;chromatin organization#GO:0006325 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115322978|UniProtKB=A0ACM8E3H7 A0ACM8E3H7 LOC115322978 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8034716|UniProtKB=A0ACM8DXU6 A0ACM8DXU6 Ack-like PTHR24418:SF444 TYROSINE-PROTEIN KINASE ACTIVATED CDC42 KINASE-LIKE catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 non-receptor tyrosine protein kinase#PC00168 IXOSC|EnsemblGenome=LOC120838018|UniProtKB=A0ACM8EJP2 A0ACM8EJP2 LOC120838018 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121833629|UniProtKB=A0ACM8FLY9 A0ACM8FLY9 LOC121833629 PTHR36943:SF2 CCHC-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327803|UniProtKB=A0ACM8E8D1 A0ACM8E8D1 LOC115327803 PTHR12197:SF251 HISTONE-LYSINE N-METHYLTRANSFERASE SMYD EG:BACR7C10.4 PROTEIN catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone modifying activity#GO:0140993;lysine N-methyltransferase activity#GO:0016278;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8040453|UniProtKB=A0ACM8DX06 A0ACM8DX06 mRpS18B PTHR13329:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN S18B SMALL RIBOSOMAL SUBUNIT PROTEIN MS40 membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121836716|UniProtKB=A0ACM8G036 A0ACM8G036 LOC121836716 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115316212|UniProtKB=A0ACM8G7M4 A0ACM8G7M4 LOC115316212 PTHR24329:SF585 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;cell development#GO:0048468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;neuron development#GO:0048666;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC115326514|UniProtKB=A0ACM8E626 A0ACM8E626 LOC115326514 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8025774|UniProtKB=A0ACM8EY97 A0ACM8EY97 LOC8025774 PTHR24394:SF64 ZINC FINGER PROTEIN CENTROSOME-ASSOCIATED ZINC FINGER PROTEIN CP190 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8037438|UniProtKB=A0ACM8FZT7 A0ACM8FZT7 LOC8037438 PTHR22727:SF15 PROTEIN CBG13728 MRH DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8053829|UniProtKB=A0ACM8FX60 A0ACM8FX60 Lim1 PTHR24208:SF105 LIM/HOMEOBOX PROTEIN LHX DLIM1 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;nervous system development#GO:0007399;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8039809|UniProtKB=A0ACM8DXG9 A0ACM8DXG9 LOC8039809 PTHR45726:SF8 LEUKOTRIENE A-4 HYDROLASE LEUKOTRIENE A(4) HYDROLASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;ether hydrolase activity#GO:0016803;peptidase activity#GO:0008233;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824 metabolic process#GO:0008152;peptide catabolic process#GO:0043171;cellular process#GO:0009987;catabolic process#GO:0009056;peptide metabolic process#GO:0006518 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8025606|UniProtKB=A0ACM8EXU4 A0ACM8EXU4 LOC8025606 PTHR23316:SF28 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 IXOSC|EnsemblGenome=LOC121836560|UniProtKB=A0ACM8G0F2 A0ACM8G0F2 LOC121836560 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115321633|UniProtKB=A0ACM8EK67 A0ACM8EK67 LOC115321633 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121835883|UniProtKB=A0ACM8FXD0 A0ACM8FXD0 LOC121835883 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8037254|UniProtKB=A0ACM8DK36 A0ACM8DK36 LOC8037254 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transporter#PC00227 IXOSC|EnsemblGenome=LOC120840285|UniProtKB=A0ACM8EPN1 A0ACM8EPN1 LOC120840285 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8044153|UniProtKB=A0ACM8F3U8 A0ACM8F3U8 LOC8044153 PTHR23121:SF9 SODIUM-DEPENDENT GLUCOSE TRANSPORTER 1 SOLUTE CARRIER FAMILY 60 MEMBER 2 transporter#PC00227 IXOSC|EnsemblGenome=LOC8035929|UniProtKB=A0ACM8E4M5 A0ACM8E4M5 fwd PTHR10048:SF22 PHOSPHATIDYLINOSITOL KINASE PHOSPHATIDYLINOSITOL 4-KINASE BETA phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;transferase activity#GO:0016740;catalytic activity#GO:0003824 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid metabolic process#GO:0006644;signaling#GO:0023052;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;phospholipid biosynthetic process#GO:0008654;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;biological regulation#GO:0065007;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;signal transduction#GO:0007165;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637 membrane#GO:0016020;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 IXOSC|EnsemblGenome=LOC8042738|UniProtKB=A0ACM8EBN5 A0ACM8EBN5 wupA PTHR13738:SF43 TROPONIN I TROPONIN I binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 multicellular organismal process#GO:0032501;system process#GO:0003008;muscle system process#GO:0003012;muscle contraction#GO:0006936 actin cytoskeleton#GO:0015629;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;myofibril#GO:0030016;contractile muscle fiber#GO:0043292;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;sarcomere#GO:0030017 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC121835430|UniProtKB=A0ACM8FV31 A0ACM8FV31 LOC121835430 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8026270|UniProtKB=A0ACM8EYM7 A0ACM8EYM7 LOC8026270 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;small molecule binding#GO:0036094;catalytic activity#GO:0003824;binding#GO:0005488;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8024166|UniProtKB=A0ACM8FT14 A0ACM8FT14 LOC8024166 PTHR24418:SF421 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE SHARK catalytic activity, acting on a protein#GO:0140096;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 non-receptor tyrosine protein kinase#PC00168 IXOSC|EnsemblGenome=LOC115329333|UniProtKB=A0ACM8FHT5 A0ACM8FHT5 LOC115329333 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839880|UniProtKB=A0ACM8EMZ0 A0ACM8EMZ0 LOC120839880 PTHR23150:SF37 SULFATASE MODIFYING FACTOR 1, 2 FORMYLGLYCINE-GENERATING ENZYME oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8036043|UniProtKB=A0ACM8E940 A0ACM8E940 Gasp PTHR23301:SF100 CHITIN BINDING PERITROPHIN-A GASP, ISOFORM A carbohydrate derivative binding#GO:0097367;binding#GO:0005488 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312 IXOSC|EnsemblGenome=LOC8051792|UniProtKB=A0ACM8ECD7 A0ACM8ECD7 LOC8051792 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8027878|UniProtKB=A0ACM8FKR2 A0ACM8FKR2 LOC8027878 PTHR11685:SF225 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF144B aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;protein binding#GO:0005515;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;binding#GO:0005488 modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;ubiquitin ligase complex#GO:0000151;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8043170|UniProtKB=A0ACM8FGG4 A0ACM8FGG4 LOC8043170 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8036290|UniProtKB=A0ACM8DTL2 A0ACM8DTL2 LOC8036290 PTHR11328:SF51 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 12 L-amino acid transmembrane transporter activity#GO:0015179;amino acid transmembrane transporter activity#GO:0015171;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943 neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;carboxylic acid transmembrane transport#GO:1905039;L-alpha-amino acid transmembrane transport#GO:1902475;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8041314|UniProtKB=A0ACM8G2U0 A0ACM8G2U0 LOC8041314 PTHR21290:SF27 SPHINGOMYELIN SYNTHETASE PHOSPHATIDYLCHOLINE:CERAMIDE CHOLINEPHOSPHOTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, for other substituted phosphate groups#GO:0016780 phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;ceramide metabolic process#GO:0006672;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;sphingomyelin metabolic process#GO:0006684;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8028368|UniProtKB=A0ACM8E8R9 A0ACM8E8R9 Mfap1 PTHR15327:SF0 MICROFIBRIL-ASSOCIATED PROTEIN MICROFIBRILLAR-ASSOCIATED PROTEIN 1 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 U2-type spliceosomal complex#GO:0005684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;spliceosomal complex#GO:0005681;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC115319418|UniProtKB=A0ACM8F3Z7 A0ACM8F3Z7 LOC115319418 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8051979|UniProtKB=A0ACM8E595 A0ACM8E595 LOC8051979 PTHR24173:SF88 ANKYRIN REPEAT CONTAINING ANKYRIN REPEAT AND SOCS BOX PROTEIN 7 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8030249|UniProtKB=A0ACM8ESZ9 A0ACM8ESZ9 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058;cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;microbody#GO:0042579;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115316764|UniProtKB=A0ACM8FRE9 A0ACM8FRE9 LOC115316764 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8038676|UniProtKB=A0ACM8FRJ6 A0ACM8FRJ6 LOC8038676 PTHR39947:SF1 IP19862P IP19862P IXOSC|EnsemblGenome=LOC8036677|UniProtKB=A0ACM8DMS0 A0ACM8DMS0 LOC8036677 PTHR22883:SF147 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096 protein targeting#GO:0006605;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization within membrane#GO:0051668;protein targeting to membrane#GO:0006612 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8023189|UniProtKB=A0ACM8G4E0 A0ACM8G4E0 LOC8023189 PTHR10584:SF166 SUGAR KINASE RIBOKINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;carbohydrate kinase activity#GO:0019200;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 carbohydrate kinase#PC00065;kinase#PC00137 IXOSC|EnsemblGenome=LOC115313277|UniProtKB=A0ACM8F066 A0ACM8F066 LOC115313277 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835789|UniProtKB=A0ACM8FVT4 A0ACM8FVT4 LOC121835789 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041199|UniProtKB=A0ACM8DNP0 A0ACM8DNP0 LOC8041199 PTHR24192:SF3 ANKYRIN REPEAT DOMAIN 40 ANKYRIN REPEAT DOMAIN 40 IXOSC|EnsemblGenome=LOC120848915|UniProtKB=A0ACM8F6M3 A0ACM8F6M3 LOC120848915 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121834285|UniProtKB=A0ACM8FQQ7 A0ACM8FQQ7 PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509 Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115317859|UniProtKB=A0ACM8DY33 A0ACM8DY33 LOC115317859 PTHR23301:SF113 CHITIN BINDING PERITROPHIN-A MUCIN RELATED 89F, ISOFORM B carbohydrate derivative binding#GO:0097367;binding#GO:0005488 external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115313675|UniProtKB=A0ACM8G1S7 A0ACM8G1S7 LOC115313675 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120841111|UniProtKB=A0ACM8ER51 A0ACM8ER51 LOC120841111 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8041204|UniProtKB=A0ACM8DNJ0 A0ACM8DNJ0 eIF3l PTHR13242:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT L translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translational initiation#GO:0006413;translation#GO:0006412 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;eukaryotic translation initiation factor 3 complex#GO:0005852 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC121834568|UniProtKB=A0ACM8FRB4 A0ACM8FRB4 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8035508|UniProtKB=A0ACM8DJR5 A0ACM8DJR5 pasi2 PTHR36694:SF4 PASIFLORA 1, ISOFORM A-RELATED LD42595P cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neurogenesis#GO:0022008;gliogenesis#GO:0042063;regulation of anatomical structure size#GO:0090066;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216;developmental process#GO:0032502;glial cell differentiation#GO:0010001;multicellular organismal process#GO:0032501;cellular component assembly#GO:0022607;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;anatomical structure development#GO:0048856;regulation of biological quality#GO:0065008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell junction organization#GO:0034330;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;cell junction assembly#GO:0034329 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8028528|UniProtKB=A0ACM8DWK9 A0ACM8DWK9 PTHR10972:SF221 OXYSTEROL-BINDING PROTEIN-RELATED OXYSTEROL-BINDING PROTEIN cholesterol binding#GO:0015485;lipid binding#GO:0008289;steroid binding#GO:0005496;alcohol binding#GO:0043178;sterol binding#GO:0032934;small molecule binding#GO:0036094;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;plasma membrane#GO:0005886;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cell periphery#GO:0071944;cytosol#GO:0005829;membrane#GO:0016020 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115311323|UniProtKB=A0ACM8EH10 A0ACM8EH10 LOC120846054 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115322294|UniProtKB=A0ACM8E2K7 A0ACM8E2K7 LOC115322294 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC8038961|UniProtKB=A0ACM8E2T5 A0ACM8E2T5 LOC8038961 PTHR11804:SF84 PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED SACCHAROLYSIN catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8025109|UniProtKB=A0ACM8DUZ3 A0ACM8DUZ3 LOC8025109 PTHR48277:SF1 MITOCHONDRIAL RIBOSOMAL PROTEIN S5 SMALL RIBOSOMAL SUBUNIT PROTEIN US5M IXOSC|EnsemblGenome=LOC115320774|UniProtKB=A0ACM8EIQ1 A0ACM8EIQ1 LOC115320774 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;cellular process#GO:0009987 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC120844101|UniProtKB=A0ACM8EXV6 A0ACM8EXV6 LOC120844101 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8033785|UniProtKB=A0ACM8DRA6 A0ACM8DRA6 LOC8033785 PTHR24355:SF18 G PROTEIN-COUPLED RECEPTOR KINASE/RIBOSOMAL PROTEIN S6 KINASE G PROTEIN-COUPLED RECEPTOR KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;G protein-coupled receptor binding#GO:0001664;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 cell communication#GO:0007154;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;G protein-coupled receptor signaling pathway#GO:0007186;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;signaling#GO:0023052;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 non-receptor serine/threonine protein kinase#PC00167 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GPRK#P00701;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GPRK#P00741;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Rhodopsin kinase#P00750;Parkinson disease#P00049>GRK#P01234;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>GRK3#P05941 IXOSC|EnsemblGenome=LOC115310016|UniProtKB=A0ACM8F607 A0ACM8F607 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120835985|UniProtKB=A0ACM8EG98 A0ACM8EG98 LOC120835985 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;microbody#GO:0042579;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8052120|UniProtKB=A0ACM8FJ94 A0ACM8FJ94 LOC8052120 PTHR12815:SF18 SORTING AND ASSEMBLY MACHINERY SAMM50 PROTEIN FAMILY MEMBER SORTING AND ASSEMBLY MACHINERY COMPONENT 50 HOMOLOG protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein insertion into mitochondrial outer membrane#GO:0045040;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;protein insertion into membrane#GO:0051205;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594 outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial outer membrane translocase complex#GO:0005742;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;organelle outer membrane#GO:0031968 IXOSC|EnsemblGenome=LOC8032746|UniProtKB=A0ACM8EAW7 A0ACM8EAW7 Ttd14 PTHR34932:SF2 TRPL TRANSLOCATION DEFECT PROTEIN 14 TRPL TRANSLOCATION DEFECT PROTEIN 14 GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;lipid binding#GO:0008289;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;nucleotide binding#GO:0000166;phospholipid binding#GO:0005543;phosphatidylinositol binding#GO:0035091 retina homeostasis#GO:0001895;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;tissue homeostasis#GO:0001894;multicellular organismal-level homeostasis#GO:0048871 IXOSC|EnsemblGenome=LOC115329189|UniProtKB=A0ACM8EA46 A0ACM8EA46 LOC115329189 PTHR20990:SF1 PEROXISOMAL BIOGENESIS FACTOR 11 PEROXISOMAL MEMBRANE PROTEIN 11C peroxisome organization#GO:0007031;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8039827|UniProtKB=A0ACM8DKG8 A0ACM8DKG8 LOC8039827 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 isomerase#PC00135 IXOSC|EnsemblGenome=LOC115308600|UniProtKB=A0ACM8DMP8 A0ACM8DMP8 Cap-G PTHR14418:SF5 CONDENSIN COMPLEX SUBUNIT 3-RELATED CONDENSIN COMPLEX SUBUNIT 3 cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;chromosome segregation#GO:0007059;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular process#GO:0009987;organelle fission#GO:0048285;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402 chromosome#GO:0005694;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;condensin complex#GO:0000796;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC121833669|UniProtKB=A0ACM8FM24 A0ACM8FM24 LOC121833669 PTHR19856:SF8 WD-REPEATCONTAINING PROTEIN WDR1 WD REPEAT-CONTAINING PROTEIN 1 protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;actin filament depolymerization#GO:0030042;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular anatomical entity morphogenesis#GO:0032989;cellular component organization or biogenesis#GO:0071840;striated muscle cell differentiation#GO:0051146;protein-containing complex organization#GO:0043933;anatomical structure formation involved in morphogenesis#GO:0048646;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;anatomical structure morphogenesis#GO:0009653;cell differentiation#GO:0030154;actomyosin structure organization#GO:0031032;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;striated muscle cell development#GO:0055002;cellular component disassembly#GO:0022411;actin polymerization or depolymerization#GO:0008154;protein depolymerization#GO:0051261;developmental process#GO:0032502;cellular developmental process#GO:0048869;actin filament organization#GO:0007015;muscle cell development#GO:0055001;myofibril assembly#GO:0030239;muscle cell differentiation#GO:0042692;actin cytoskeleton organization#GO:0030036;muscle structure development#GO:0061061;protein-containing complex disassembly#GO:0032984;organelle assembly#GO:0070925;cellular component assembly involved in morphogenesis#GO:0010927;actin filament-based process#GO:0030029;sarcomere organization#GO:0045214;anatomical structure development#GO:0048856;supramolecular fiber organization#GO:0097435 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC121837345|UniProtKB=A0ACM8G391 A0ACM8G391 LOC121837345 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8030431|UniProtKB=A0ACM8E4U5 A0ACM8E4U5 LOC8030431 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8025626|UniProtKB=A0ACM8DS40 A0ACM8DS40 LOC8025626 PTHR12106:SF27 SORTILIN RELATED PDZ DOMAIN-CONTAINING PROTEIN membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8051920|UniProtKB=A0ACM8DR56 A0ACM8DR56 Smg5 PTHR15696:SF7 SMG-7 SUPPRESSOR WITH MORPHOLOGICAL EFFECT ON GENITALIA PROTEIN 7 NONSENSE-MEDIATED MRNA DECAY FACTOR RNA binding#GO:0003723;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;nucleic acid binding#GO:0003676;binding#GO:0005488 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121835309|UniProtKB=A0ACM8FU94 A0ACM8FU94 LOC121835309 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8040971|UniProtKB=A0ACM8EFD9 A0ACM8EFD9 LOC8040971 PTHR17985:SF28 SER/THR-RICH PROTEIN T10 IN DGCR REGION TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG cellular component organization#GO:0016043;protein localization to extracellular region#GO:0071692;Golgi organization#GO:0007030;export from cell#GO:0140352;secretion#GO:0046903;protein secretion#GO:0009306;localization#GO:0051179;protein transport#GO:0015031;secretion by cell#GO:0032940;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;endomembrane system organization#GO:0010256;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120839868|UniProtKB=A0ACM8ENV2 A0ACM8ENV2 PTHR16466:SF6 TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 telomere organization#GO:0032200;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;telomere maintenance via telomere lengthening#GO:0010833;cellular process#GO:0009987;telomere capping#GO:0016233;organelle organization#GO:0006996;response to stress#GO:0006950 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;nuclear telomere cap complex#GO:0000783;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;chromosome, telomeric region#GO:0000781;protein-containing complex#GO:0032991;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC115318452|UniProtKB=A0ACM8ES41 A0ACM8ES41 LOC115318452 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024960|UniProtKB=A0ACM8DQ20 A0ACM8DQ20 LOC8024960 PTHR45632:SF3 LD33804P KELCH-LIKE PROTEIN DIABLO ubiquitin-like ligase-substrate adaptor activity#GO:1990756;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767 ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul3-RING ubiquitin ligase complex#GO:0031463;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;catalytic complex#GO:1902494;transferase complex#GO:1990234 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120840107|UniProtKB=A0ACM8G2V0 A0ACM8G2V0 LOC120840107 PTHR11792:SF17 ARRESTIN KURTZ ARRESTIN protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;binding#GO:0005488;signaling receptor binding#GO:0005102 localization#GO:0051179;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;sensory perception#GO:0007600;nervous system process#GO:0050877;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;negative regulation of G protein-coupled receptor signaling pathway#GO:0045744;regulation of biological process#GO:0050789;establishment of localization#GO:0051234;import into cell#GO:0098657;receptor-mediated endocytosis#GO:0006898;system process#GO:0003008;negative regulation of cellular process#GO:0048523;regulation of G protein-coupled receptor signaling pathway#GO:0008277;transport#GO:0006810;regulation of response to stimulus#GO:0048583;multicellular organismal process#GO:0032501;negative regulation of response to stimulus#GO:0048585;vesicle-mediated transport#GO:0016192;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;receptor internalization#GO:0031623;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>beta-arrestin#P00880;Wnt signaling pathway#P00057>beta-arrestin#P01456;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>beta-arrestin#P00723 IXOSC|EnsemblGenome=LOC8033806|UniProtKB=A0ACM8G4C1 A0ACM8G4C1 B9d2 PTHR12968:SF2 B9 DOMAIN-CONTAINING B9 DOMAIN-CONTAINING PROTEIN 2 cellular component organization#GO:0016043;cilium assembly#GO:0060271;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cilium#GO:0005929;ciliary transition zone#GO:0035869 structural protein#PC00211 IXOSC|EnsemblGenome=LOC120840502|UniProtKB=A0ACM8ENU2 A0ACM8ENU2 LOC120840502 PTHR23074:SF83 AAA DOMAIN-CONTAINING VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 4A hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular localization#GO:0051641;protein metabolic process#GO:0019538;localization#GO:0051179;vacuole organization#GO:0007033;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;endosomal transport#GO:0016197;intracellular transport#GO:0046907;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;transport#GO:0006810;vesicle-mediated transport#GO:0016192;ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway#GO:0043162;endosome transport via multivesicular body sorting pathway#GO:0032509;organelle organization#GO:0006996;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vesicle#GO:0031982;intracellular vesicle#GO:0097708 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC120848418|UniProtKB=A0ACM8F4U5 A0ACM8F4U5 LOC120848418 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313073|UniProtKB=A0ACM8EYX3 A0ACM8EYX3 LOC115313073 PTHR12472:SF1 RAB3-GAP REGULATORY DOMAIN RAB3 GTPASE-ACTIVATING PROTEIN NON-CATALYTIC SUBUNIT binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;molecular function regulator activity#GO:0098772 metabolic process#GO:0008152;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;autophagy#GO:0006914;synaptic signaling#GO:0099536;establishment of protein localization to membrane#GO:0090150;macroautophagy#GO:0016236;establishment of protein localization to endoplasmic reticulum#GO:0072599;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;localization within membrane#GO:0051668;process utilizing autophagic mechanism#GO:0061919;cellular localization#GO:0051641;localization#GO:0051179;cell communication#GO:0007154;regulation of biological process#GO:0050789;signaling#GO:0023052;catabolic process#GO:0009056 synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;presynapse#GO:0098793;plasma membrane region#GO:0098590;presynaptic membrane#GO:0042734;cytoplasm#GO:0005737;plasma membrane#GO:0005886;vacuole#GO:0005773;autophagosome#GO:0005776;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC115331657|UniProtKB=A0ACM8F7E4 A0ACM8F7E4 LOC115331657 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8040692|UniProtKB=A0ACM8FJI6 A0ACM8FJI6 LOC8040692 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310613|UniProtKB=A0ACM8EJS4 A0ACM8EJS4 LOC115310613 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115316013|UniProtKB=A0ACM8EWZ6 A0ACM8EWZ6 LOC115316013 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8027268|UniProtKB=A0ACM8DPE8 A0ACM8DPE8 LOC8027268 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120843557|UniProtKB=A0ACM8FET8 A0ACM8FET8 LOC120843557 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120840848|UniProtKB=A0ACM8EQL0 A0ACM8EQL0 LOC120840848 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8053149|UniProtKB=A0ACM8G696 A0ACM8G696 LOC8053149 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=LOC8034950|UniProtKB=A0ACM8EYB5 A0ACM8EYB5 LOC8034950 PTHR23088:SF55 NITRILASE-RELATED NITRILASE AND FRAGILE HISTIDINE TRIAD FUSION PROTEIN NITFHIT catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;metabolic process#GO:0008152;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121833800|UniProtKB=A0ACM8FLQ5 A0ACM8FLQ5 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115331183|UniProtKB=A0ACM8FCV1 A0ACM8FCV1 MED9 PTHR20844:SF0 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION, SUBUNIT 9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 9 core mediator complex#GO:0070847;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC115324977|UniProtKB=A0ACM8E592 A0ACM8E592 LOC115324977 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053877|UniProtKB=A0ACM8E2D0 A0ACM8E2D0 LOC8053877 PTHR33538:SF1 PROTEIN GAMETE EXPRESSED 1 PROTEIN BRAMBLEBERRY organelle fusion#GO:0048284;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle membrane fusion#GO:0090174;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;single fertilization#GO:0007338;cellular process#GO:0009987;nuclear membrane organization#GO:0071763;cellular component organization or biogenesis#GO:0071840;nucleus organization#GO:0006997;mitotic cell cycle process#GO:1903047;nuclear envelope organization#GO:0006998;mitotic cell cycle#GO:0000278;reproductive process#GO:0022414;fertilization#GO:0009566;cell cycle#GO:0007049;cellular component organization#GO:0016043;membrane assembly#GO:0071709;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;organelle fission#GO:0048285;nuclear division#GO:0000280;sexual reproduction#GO:0019953 IXOSC|EnsemblGenome=LOC121046498|UniProtKB=A0ACM8FKE9 A0ACM8FKE9 LOC121046498 PTHR10983:SF73 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE EPSILON acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;phospholipid metabolic process#GO:0006644;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987;metabolic process#GO:0008152;phosphatidylinositol metabolic process#GO:0046488;lipid metabolic process#GO:0006629 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120837934|UniProtKB=A0ACM8EJC7 A0ACM8EJC7 LOC120837934 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039442|UniProtKB=A0ACM8E2B4 A0ACM8E2B4 LOC8039442 PTHR18945:SF945 NEUROTRANSMITTER GATED ION CHANNEL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-LIKE 1 monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;gated channel activity#GO:0022836;postsynaptic neurotransmitter receptor activity#GO:0098960;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 anterograde trans-synaptic signaling#GO:0098916;metal ion transport#GO:0030001;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;trans-synaptic signaling#GO:0099537;synaptic transmission, cholinergic#GO:0007271;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;calcium ion transport#GO:0006816;transport#GO:0006810 cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ligand-gated ion channel#PC00141 Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC120843088|UniProtKB=A0ACM8EVA5 A0ACM8EVA5 LOC120843088 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8034035|UniProtKB=A0ACM8DQA0 A0ACM8DQA0 LOC8034035 PTHR43247:SF1 PHOSPHOSERINE AMINOTRANSFERASE PHOSPHOSERINE AMINOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;heterocyclic compound binding#GO:1901363;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;transaminase activity#GO:0008483 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;proteinogenic amino acid biosynthetic process#GO:0170038 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transaminase#PC00216 Vitamin B6 metabolism#P02787>Phosphoserine transaminase#P03227;Serine glycine biosynthesis#P02776>Phosphoserine aminotransferase#P03157;Pyridoxal-5-phosphate biosynthesis#P02759>Phosphohydroxythreonine aminotransferase#P03058 IXOSC|EnsemblGenome=LOC8052257|UniProtKB=A0ACM8FMG6 A0ACM8FMG6 PTHR46669:SF1 LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL LEUCINE-RICH PPR MOTIF-CONTAINING PROTEIN, MITOCHONDRIAL RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8051100|UniProtKB=A0ACM8F5Z1 A0ACM8F5Z1 LOC8051100 PTHR23516:SF23 SAM (S-ADENOSYL METHIONINE) TRANSPORTER MOLYBDATE-ANION TRANSPORTER transporter#PC00227 IXOSC|EnsemblGenome=LOC8040017|UniProtKB=A0ACM8FR31 A0ACM8FR31 PTHR11920:SF462 GUANYLYL CYCLASE GUANYLATE CYCLASE cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;lyase activity#GO:0016829 regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cGMP biosynthetic process#GO:0006182;organophosphate biosynthetic process#GO:0090407;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;ribose phosphate biosynthetic process#GO:0046390;receptor guanylyl cyclase signaling pathway#GO:0007168;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 lyase#PC00144;guanylate cyclase#PC00114 IXOSC|EnsemblGenome=LOC8027346|UniProtKB=A0ACM8DIX4 A0ACM8DIX4 LOC8027346 PTHR11178:SF1 IRON-SULFUR CLUSTER SCAFFOLD PROTEIN NFU-RELATED NFU1 IRON-SULFUR CLUSTER SCAFFOLD HOMOLOG, MITOCHONDRIAL iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8039098|UniProtKB=A0ACM8E6N0 A0ACM8E6N0 LOC8039098 PTHR10183:SF379 CALPAIN CALPAIN-A-RELATED protease#PC00190;cysteine protease#PC00081 Huntington disease#P00029>Calpain#P00788 IXOSC|EnsemblGenome=LOC8044156|UniProtKB=A0ACM8DL77 A0ACM8DL77 LOC8044156 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121835641|UniProtKB=A0ACM8FUI3 A0ACM8FUI3 LOC121835641 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC115327123|UniProtKB=A0ACM8G1Y3 A0ACM8G1Y3 LOC115327123 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8037446|UniProtKB=A0ACM8EQQ6 A0ACM8EQQ6 LOC8037446 PTHR12411:SF917 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L, LIKE-RELATED catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC115313248|UniProtKB=A0ACM8FPV2 A0ACM8FPV2 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034699|UniProtKB=A0ACM8DXX0 A0ACM8DXX0 LOC8034699 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC120841216|UniProtKB=A0ACM8ES77 A0ACM8ES77 LOC120841216 PTHR11214:SF391 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE BRE-2-RELATED glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121834080|UniProtKB=A0ACM8FNW1 A0ACM8FNW1 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850557|UniProtKB=A0ACM8FA91 A0ACM8FA91 LOC120850557 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8026215|UniProtKB=A0ACM8DHE7 A0ACM8DHE7 LOC8026215 PTHR31525:SF1 HEME TRANSPORTER HRG1 HEME TRANSPORTER HRG1 tetrapyrrole binding#GO:0046906;binding#GO:0005488;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;heme binding#GO:0020037 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;iron coordination entity transport#GO:1901678;iron ion transport#GO:0006826;transport#GO:0006810;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;nitrogen compound transport#GO:0071705 lytic vacuole#GO:0000323;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;cell periphery#GO:0071944;lysosomal membrane#GO:0005765;vacuole#GO:0005773;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227 IXOSC|EnsemblGenome=LOC121838554|UniProtKB=A0ACM8G8G5 A0ACM8G8G5 LOC121838554 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220 IXOSC|EnsemblGenome=LOC120842698|UniProtKB=A0ACM8EUA2 A0ACM8EUA2 LOC120842698 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843229|UniProtKB=A0ACM8G891 A0ACM8G891 LOC120843229 PTHR24381:SF486 ZINC FINGER PROTEIN ADULT ENHANCER FACTOR 1-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8030768|UniProtKB=A0ACM8DYQ7 A0ACM8DYQ7 LOC8030768 PTHR10177:SF629 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B3 cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887 mitotic cell cycle process#GO:1903047;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC120838273|UniProtKB=A0ACM8EKF7 A0ACM8EKF7 LOC120838273 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8038271|UniProtKB=A0ACM8E2C6 A0ACM8E2C6 LOC8038271 PTHR46040:SF3 HIGH MOBILITY GROUP PROTEIN 2 HIGH MOBILITY GROUP PROTEIN 2 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8033349|UniProtKB=A0ACM8EN90 A0ACM8EN90 LOC8033349 PTHR23324:SF66 SEC14 RELATED PROTEIN PROTEIN REAL-TIME cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120839329|UniProtKB=A0ACM8ELM5 A0ACM8ELM5 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC120843251|UniProtKB=A0ACM8EVL6 A0ACM8EVL6 LOC120843251 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8025063|UniProtKB=A0ACM8FR13 A0ACM8FR13 LOC8025063 PTHR11188:SF17 ARRESTIN DOMAIN CONTAINING PROTEIN LD44267P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8030084|UniProtKB=A0ACM8DJ85 A0ACM8DJ85 LOC8030084 PTHR11886:SF35 DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN 1, CYTOPLASMIC-RELATED binding#GO:0005488;protein binding#GO:0005515 microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule or microtubule-binding cytoskeletal protein#PC00157 Huntington disease#P00029>Dynein complex#P00774 IXOSC|EnsemblGenome=LOC120843583|UniProtKB=A0ACM8EW84 A0ACM8EW84 LOC120843583 PTHR33147:SF39 DEFENSIN-LIKE PROTEIN 1 DEFENSIN-LIKE PROTEIN 98 response to stress#GO:0006950;response to stimulus#GO:0050896;defense response#GO:0006952 antimicrobial response protein#PC00051 IXOSC|EnsemblGenome=LOC8024191|UniProtKB=A0ACM8FRH6 A0ACM8FRH6 LOC8024191 PTHR46420:SF1 BETA-1,4-GLUCURONYLTRANSFERASE 1 BETA-1,4-GLUCURONYLTRANSFERASE 1 transferase activity#GO:0016740;glucuronosyltransferase activity#GO:0015020;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757 protein O-linked glycosylation via mannose#GO:0035269;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 transferase#PC00220 IXOSC|EnsemblGenome=LOC121838191|UniProtKB=A0ACM8G717 A0ACM8G717 LOC121838191 PTHR22883:SF511 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 developmental process#GO:0032502;protein targeting to membrane#GO:0006612;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;synaptic vesicle maturation#GO:0016188;cellular process#GO:0009987;establishment of protein localization#GO:0045184;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;developmental maturation#GO:0021700;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular component organization#GO:0016043;protein targeting#GO:0006605 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8037831|UniProtKB=A0ACM8EB98 A0ACM8EB98 PMCA PTHR24093:SF535 CATION TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 regulation of cytosolic calcium ion concentration#GO:0051480;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;calcium ion homeostasis#GO:0055074;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082 membrane#GO:0016020;cell periphery#GO:0071944;organelle#GO:0043226;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC121836403|UniProtKB=A0ACM8FYK4 A0ACM8FYK4 LOC121836403 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8034885|UniProtKB=A0ACM8ESX3 A0ACM8ESX3 Grip163 PTHR19302:SF70 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 6 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;spindle assembly#GO:0051225;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;microtubule polymerization#GO:0046785;meiotic cell cycle#GO:0051321;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;cytoplasmic microtubule organization#GO:0031122;reproductive process#GO:0022414;cell cycle#GO:0007049;microtubule nucleation#GO:0007020;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein polymerization#GO:0051258;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;organelle assembly#GO:0070925;sexual reproduction#GO:0019953 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC115323237|UniProtKB=A0ACM8E2U7 A0ACM8E2U7 LOC115323237 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843926|UniProtKB=A0ACM8EWX1 A0ACM8EWX1 LOC120843926 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115317550|UniProtKB=A0ACM8EX21 A0ACM8EX21 LOC115317550 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840047|UniProtKB=A0ACM8ENN1 A0ACM8ENN1 LOC120840047 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115321649|UniProtKB=A0ACM8FSP6 A0ACM8FSP6 LOC115321649 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120843889|UniProtKB=A0ACM8EWU1 A0ACM8EWU1 LOC120843889 PTHR37162:SF13 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834733|UniProtKB=A0ACM8FRU1 A0ACM8FRU1 LOC121834733 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121833008|UniProtKB=A0ACM8FJZ0 A0ACM8FJZ0 LOC121833008 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309914|UniProtKB=A0ACM8DP95 A0ACM8DP95 LOC115309914 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC121047661|UniProtKB=A0ACM8G629 A0ACM8G629 LOC121047661 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC121833381|UniProtKB=A0ACM8FJC6 A0ACM8FJC6 LOC121833381 PTHR33426:SF52 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8025361|UniProtKB=A0ACM8EWI6 A0ACM8EWI6 LOC8025361 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transporter#PC00227 IXOSC|EnsemblGenome=LOC121048124|UniProtKB=A0ACM8FHN2 A0ACM8FHN2 LOC121048124 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120851093|UniProtKB=A0ACM8FC33 A0ACM8FC33 LOC120851093 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8052023|UniProtKB=A0ACM8F5H7 A0ACM8F5H7 LOC8052023 PTHR12231:SF275 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 cellular process#GO:0009987;cell adhesion#GO:0007155;cell-cell adhesion#GO:0098609 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cell junction#GO:0030054 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115326458|UniProtKB=A0ACM8E7E5 A0ACM8E7E5 LOC115326458 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 transferase#PC00220 IXOSC|EnsemblGenome=LOC121835468|UniProtKB=A0ACM8FUW6 A0ACM8FUW6 LOC121835468 PTHR43568:SF1 P PROTEIN CITRATE TRANSPORTER-LIKE DOMAIN-CONTAINING PROTEIN-RELATED transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8026331|UniProtKB=A0ACM8DMP9 A0ACM8DMP9 LOC8026331 PTHR24072:SF398 RHO FAMILY GTPASE RAS-LIKE GTP-BINDING PROTEIN RHO1 ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;protein binding#GO:0005515;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 signaling#GO:0023052;regulation of cellular process#GO:0050794;cell motility#GO:0048870;actin cytoskeleton organization#GO:0030036;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of cytoskeleton organization#GO:0051493;regulation of organelle organization#GO:0033043;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;supramolecular fiber organization#GO:0097435;cell communication#GO:0007154;actin filament-based process#GO:0030029;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cell migration#GO:0016477;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;regulation of actin filament-based process#GO:0032970 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 small GTPase#PC00208;G-protein#PC00020 Ras Pathway#P04393>Rho#P04578;Axon guidance mediated by Slit/Robo#P00008>Rho#P00355;Integrin signalling pathway#P00034>Rho#P00948;Angiogenesis#P00005>GTPase#P00254;Cytoskeletal regulation by Rho GTPase#P00016>Rho#P00507 IXOSC|EnsemblGenome=LOC8052222|UniProtKB=A0ACM8E803 A0ACM8E803 Nsun5 PTHR22807:SF4 NOP2 YEAST -RELATED NOL1/NOP2/FMU SUN DOMAIN-CONTAINING 28S RRNA (CYTOSINE-C(5))-METHYLTRANSFERASE methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a rRNA#GO:0140102;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;RNA methyltransferase activity#GO:0008173;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098 positive regulation of biosynthetic process#GO:0009891;macromolecule modification#GO:0043412;RNA methylation#GO:0001510;positive regulation of translation#GO:0045727;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;post-transcriptional regulation of gene expression#GO:0010608;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;ribosome biogenesis#GO:0042254;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;positive regulation of protein metabolic process#GO:0051247;RNA modification#GO:0009451;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;methylation#GO:0032259;RNA metabolic process#GO:0016070;rRNA modification#GO:0000154;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;cellular component biogenesis#GO:0044085;regulation of protein metabolic process#GO:0051246;positive regulation of biological process#GO:0048518;rRNA base methylation#GO:0070475;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;RNA processing#GO:0006396 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC121836659|UniProtKB=A0ACM8G0G7 A0ACM8G0G7 LOC121836659 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC8036233|UniProtKB=A0ACM8E3S2 A0ACM8E3S2 ATPsynO PTHR11910:SF1 ATP SYNTHASE DELTA CHAIN ATP SYNTHASE PERIPHERAL STALK SUBUNIT OSCP, MITOCHONDRIAL proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;proton channel activity#GO:0015252;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligase activity#GO:0016874 nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137;ATP biosynthetic process#GO:0006754;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;ATP metabolic process#GO:0046034;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;energy derivation by oxidation of organic compounds#GO:0015980;nucleoside phosphate biosynthetic process#GO:1901293;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;nucleoside triphosphate biosynthetic process#GO:0009142;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;oxidative phosphorylation#GO:0006119;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;proton motive force-driven ATP synthesis#GO:0015986;purine nucleoside triphosphate biosynthetic process#GO:0009145;purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 primary active transporter#PC00068;transporter#PC00227;ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC121045535|UniProtKB=A0ACM8FNZ6 A0ACM8FNZ6 PTHR24416:SF619 TYROSINE-PROTEIN KINASE RECEPTOR NT-3 GROWTH FACTOR RECEPTOR-RELATED transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein kinase activity#GO:0004672;protein binding#GO:0005515;growth factor binding#GO:0019838;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity#GO:0016740;signaling receptor activity#GO:0038023 response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cellular response to growth factor stimulus#GO:0071363;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to nerve growth factor stimulus#GO:1990090;cell surface receptor signaling pathway#GO:0007166 axon#GO:0030424;signaling receptor complex#GO:0043235;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115317939|UniProtKB=A0ACM8FN71 A0ACM8FN71 PTHR20855:SF152 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097;cytokine-mediated signaling pathway#GO:0019221;cellular response to chemical stimulus#GO:0070887;response to peptide#GO:1901652;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115312541|UniProtKB=A0ACM8DS03 A0ACM8DS03 LOC115312541 PTHR19375:SF565 HEAT SHOCK PROTEIN 70KDA HEAT SHOCK COGNATE 71 KDA PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;heat shock protein binding#GO:0031072;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP-dependent activity#GO:0140657;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein refolding#GO:0042026;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC115309198|UniProtKB=A0ACM8FAX1 A0ACM8FAX1 LOC115309198 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8051842|UniProtKB=A0ACM8DT62 A0ACM8DT62 LOC8051842 PTHR22760:SF2 GLYCOSYLTRANSFERASE ALPHA-1,2-MANNOSYLTRANSFERASE ALG9 glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;glycoprotein biosynthetic process#GO:0009101 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120847772|UniProtKB=A0ACM8F5K7 A0ACM8F5K7 LOC120847772 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326368|UniProtKB=A0ACM8FF41 A0ACM8FF41 spict PTHR12570:SF92 DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_5G07070)-RELATED SPICHTHYIN, ISOFORM B transport#GO:0006810;magnesium ion transport#GO:0015693;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115309967|UniProtKB=A0ACM8DP51 A0ACM8DP51 LOC115309967 PTHR43605:SF17 ACYL-COENZYME A SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;transferase activity#GO:0016740;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;organophosphate metabolic process#GO:0019637;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;monocarboxylic acid biosynthetic process#GO:0072330;purine-containing compound metabolic process#GO:0072521;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041583|UniProtKB=A0ACM8E782 A0ACM8E782 LOC8041583 PTHR46754:SF1 MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN MKI67 FHA DOMAIN-INTERACTING NUCLEOLAR PHOSPHOPROTEIN RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121834692|UniProtKB=A0ACM8FQG9 A0ACM8FQG9 PTHR47969:SF41 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED KINESIN-LIKE PROTEIN KIF21A ISOFORM X1 macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;polypeptide conformation or assembly isomerase activity#GO:0120544;isomerase activity#GO:0016853;microtubule motor activity#GO:0003777;cytoskeletal motor activity#GO:0003774 chromosome segregation#GO:0007059;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 microtubule binding motor protein#PC00156;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8027391|UniProtKB=A0ACM8E5W7 A0ACM8E5W7 TyrRS-m PTHR11766:SF0 TYROSYL-TRNA SYNTHETASE TYROSINE--TRNA LIGASE, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8024829|UniProtKB=A0ACM8DIQ5 A0ACM8DIQ5 LOC8024829 PTHR15375:SF26 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN CHIFFON kinase activator#PC00138;kinase modulator#PC00140 IXOSC|EnsemblGenome=LOC8036689|UniProtKB=A0ACM8EMC0 A0ACM8EMC0 LOC8036689 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332173|UniProtKB=A0ACM8FV85 A0ACM8FV85 LOC115332173 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120838934|UniProtKB=A0ACM8EL36 A0ACM8EL36 LOC120838934 PTHR23427:SF15 SURFEIT LOCUS PROTEIN SURFEIT LOCUS PROTEIN 1 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component organization or biogenesis#GO:0071840;respiratory chain complex IV assembly#GO:0008535;protein-containing complex organization#GO:0043933 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115323735|UniProtKB=A0ACM8G3M8 A0ACM8G3M8 LOC115323735 PTHR24393:SF175 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8026892|UniProtKB=A0ACM8DIJ0 A0ACM8DIJ0 LOC8026892 PTHR11588:SF504 TUBULIN TUBULIN BETA-1 CHAIN-RELATED heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;ribonucleotide binding#GO:0032553;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;guanyl nucleotide binding#GO:0019001;nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;cellular process#GO:0009987;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017 intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;organelle#GO:0043226;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630 tubulin#PC00228;cytoskeletal protein#PC00085 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 IXOSC|EnsemblGenome=LOC121837118|UniProtKB=A0ACM8G2A1 A0ACM8G2A1 LOC121837118 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8031519|UniProtKB=A0ACM8EEC7 A0ACM8EEC7 LOC8031519 PTHR31350:SF21 SI:DKEY-261L7.2 F-BOX ONLY PROTEIN 21 IXOSC|EnsemblGenome=LOC120844333|UniProtKB=A0ACM8EYA5 A0ACM8EYA5 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025591|UniProtKB=A0ACM8FJF3 A0ACM8FJF3 LOC8025591 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115320727|UniProtKB=A0ACM8ERU8 A0ACM8ERU8 LOC115320727 PTHR11113:SF14 N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;deacylase activity#GO:0160215;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;deacetylase activity#GO:0019213;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;amino sugar catabolic process#GO:0046348;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 metabolite interconversion enzyme#PC00262;deacetylase#PC00087 N-acetylglucosamine metabolism#P02756>N-acetylglucosamine-6-phosphate deacetylase#P03036 IXOSC|EnsemblGenome=LOC8038853|UniProtKB=A0ACM8ESW4 A0ACM8ESW4 LOC8038853 PTHR20992:SF9 AT15442P-RELATED AT15442P-RELATED IXOSC|EnsemblGenome=LOC121834176|UniProtKB=A0ACM8FQB6 A0ACM8FQB6 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844104|UniProtKB=A0ACM8EYY6 A0ACM8EYY6 LOC120844104 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115319828|UniProtKB=A0ACM8EFM7 A0ACM8EFM7 LOC115319828 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120844781|UniProtKB=A0ACM8EZN9 A0ACM8EZN9 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120846782|UniProtKB=A0ACM8F395 A0ACM8F395 LOC120846782 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115311960|UniProtKB=A0ACM8DRE8 A0ACM8DRE8 LOC115311960 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120841259|UniProtKB=A0ACM8EQW3 A0ACM8EQW3 LOC120841259 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317434|UniProtKB=A0ACM8FBM1 A0ACM8FBM1 LOC115317434 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8031488|UniProtKB=A0ACM8DIB4 A0ACM8DIB4 eIF1A PTHR21668:SF0 EIF-1A EUKARYOTIC TRANSLATION INITIATION FACTOR 4C translation factor activity#GO:0180051;translation initiation factor activity#GO:0003743 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translational protein#PC00263;translation factor#PC00223;translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8040590|UniProtKB=A0ACM8G4F7 A0ACM8G4F7 LOC8040590 PTHR10736:SF65 BESTROPHIN BESTROPHIN 1, ISOFORM C-RELATED monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;chloride channel activity#GO:0005254;chloride transmembrane transporter activity#GO:0015108;passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8031245|UniProtKB=A0ACM8DI24 A0ACM8DI24 LOC8031245 PTHR16134:SF18 F-BOX/TPR REPEAT PROTEIN POF3 F-BOX_LRR-REPEAT PROTEIN 17 enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;photoperiodism#GO:0009648;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;response to external stimulus#GO:0009605;cellular process#GO:0009987;response to radiation#GO:0009314;regulation of circadian rhythm#GO:0042752;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to light stimulus#GO:0009416 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8031993|UniProtKB=A0ACM8FUR9 A0ACM8FUR9 LOC8031993 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion homeostasis#GO:0050801 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC115312659|UniProtKB=A0ACM8DSB9 A0ACM8DSB9 mRpS21 PTHR21109:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S21 SMALL RIBOSOMAL SUBUNIT PROTEIN BS21M ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC121834698|UniProtKB=A0ACM8FPI4 A0ACM8FPI4 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;binding#GO:0005488;catalytic activity#GO:0003824;small molecule binding#GO:0036094;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8050681|UniProtKB=A0ACM8FYB2 A0ACM8FYB2 LOC8050681 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120844038|UniProtKB=A0ACM8EYP4 A0ACM8EYP4 LOC120844038 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052972|UniProtKB=A0ACM8EVE2 A0ACM8EVE2 Zip48C PTHR11040:SF211 ZINC/IRON TRANSPORTER ZINC TRANSPORTER ZIP11 metal ion transmembrane transporter activity#GO:0046873;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;zinc ion transmembrane transporter activity#GO:0005385;transition metal ion transmembrane transporter activity#GO:0046915 transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8027832|UniProtKB=A0ACM8EV36 A0ACM8EV36 LOC8027832 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115316281|UniProtKB=A0ACM8ERI5 A0ACM8ERI5 LOC115316281 PTHR43564:SF2 KYNURENINE FORMAMIDASE-LIKE PROTEIN BLR6059 PROTEIN IXOSC|EnsemblGenome=LOC8042592|UniProtKB=A0ACM8DKY5 A0ACM8DKY5 SF2 PTHR23147:SF76 SERINE/ARGININE RICH SPLICING FACTOR LD40489P membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear speck#GO:0016607;organelle lumen#GO:0043233 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8024807|UniProtKB=A0ACM8FUG8 A0ACM8FUG8 HERC2 PTHR22870:SF398 REGULATOR OF CHROMOSOME CONDENSATION E3 UBIQUITIN-PROTEIN LIGASE HERC2 ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8052610|UniProtKB=A0ACM8DM24 A0ACM8DM24 PTHR24339:SF67 HOMEOBOX PROTEIN EMX-RELATED GNOT2 HOMEODOMAIN PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC115324877|UniProtKB=A0ACM8FPZ9 A0ACM8FPZ9 LOC115324877 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120841507|UniProtKB=A0ACM8ERD9 A0ACM8ERD9 LOC120841507 PTHR21508:SF5 MITOGUARDIN MITOGUARDIN cellular component organization#GO:0016043;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005 IXOSC|EnsemblGenome=LOC115314554|UniProtKB=A0ACM8EXQ2 A0ACM8EXQ2 LOC115314554 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032555|UniProtKB=A0ACM8FSY3 A0ACM8FSY3 LOC8032555 PTHR20937:SF3 IP14615P IP14615P transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;mesoderm development#GO:0007498;multicellular organism development#GO:0007275;embryonic morphogenesis#GO:0048598;anatomical structure formation involved in morphogenesis#GO:0048646;regulation of gene expression#GO:0010468;developmental process#GO:0032502;multicellular organismal process#GO:0032501;tissue development#GO:0009888;mesoderm formation#GO:0001707;regulation of nucleobase-containing compound metabolic process#GO:0019219;embryo development#GO:0009790;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;tissue morphogenesis#GO:0048729;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;formation of primary germ layer#GO:0001704;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;gastrulation#GO:0007369;mesoderm morphogenesis#GO:0048332;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120849933|UniProtKB=A0ACM8F932 A0ACM8F932 LOC120849933 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8024888|UniProtKB=A0ACM8DIR3 A0ACM8DIR3 LOC8024888 PTHR10516:SF443 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FK506-BINDING PROTEIN 59 cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein folding#GO:0006457;gene expression#GO:0010467;protein maturation#GO:0051604 chaperone#PC00072 TGF-beta signaling pathway#P00052>FKBP12#P01288 IXOSC|EnsemblGenome=LOC115333213|UniProtKB=A0ACM8EES8 A0ACM8EES8 LOC115333213 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 oxoacid metabolic process#GO:0043436;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;small molecule metabolic process#GO:0044281;very long-chain fatty acid metabolic process#GO:0000038;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8041073|UniProtKB=A0ACM8E8C6 A0ACM8E8C6 Elp1 PTHR12747:SF0 ELONGATOR COMPLEX PROTEIN 1 ELONGATOR COMPLEX PROTEIN 1 tRNA binding#GO:0000049;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble base modification#GO:0002097;tRNA wobble uridine modification#GO:0002098;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;cytoplasm#GO:0005737;elongator holoenzyme complex#GO:0033588;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytosol#GO:0005829 general transcription factor#PC00259 PDGF signaling pathway#P00047>Ikk#P01146 IXOSC|EnsemblGenome=LOC120836072|UniProtKB=A0ACM8FDZ3 A0ACM8FDZ3 LOC8033351 PTHR23423:SF21 ORGANIC SOLUTE TRANSPORTER-RELATED ORGANIC SOLUTE TRANSPORTER SUBUNIT ALPHA transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115312825|UniProtKB=A0ACM8EU61 A0ACM8EU61 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042564|UniProtKB=A0ACM8FX48 A0ACM8FX48 LOC8042564 PTHR24060:SF179 METABOTROPIC GLUTAMATE RECEPTOR MANGETOUT, ISOFORM G signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066 cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115315600|UniProtKB=A0ACM8G0K0 A0ACM8G0K0 Polr3K PTHR11239:SF12 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC10 transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098 DNA-templated transcription termination#GO:0006353;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;transcription by RNA polymerase III#GO:0006383;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513 DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC8030311|UniProtKB=A0ACM8FJF9 A0ACM8FJF9 LOC8030311 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC8031162|UniProtKB=A0ACM8EUC4 A0ACM8EUC4 LOC8031162 PTHR12904:SF23 FAMILY NOT NAMED PROTEIN ZER-1 HOMOLOG ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC121838206|UniProtKB=A0ACM8G739 A0ACM8G739 LOC121838206 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030287|UniProtKB=A0ACM8DYC4 A0ACM8DYC4 Ets97D PTHR11849:SF195 ETS GA-BINDING PROTEIN ALPHA CHAIN DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of biological process#GO:0050789;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 PDGF signaling pathway#P00047>Ets#P01167 IXOSC|EnsemblGenome=LOC115308429|UniProtKB=A0ACM8ELT7 A0ACM8ELT7 LOC115308429 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041424|UniProtKB=A0ACM8E6D1 A0ACM8E6D1 LOC8041424 PTHR15073:SF19 MICROTUBULE-ASSOCIATED PROTEIN ENSCONSIN, ISOFORM F regulation of biological process#GO:0050789;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of microtubule-based movement#GO:0060632;regulation of cellular process#GO:0050794;microtubule bundle formation#GO:0001578;regulation of microtubule-based process#GO:0032886;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC8031700|UniProtKB=A0ACM8DIK8 A0ACM8DIK8 LOC8031700 PTHR44873:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL DNAJ HOMOLOG SUBFAMILY C MEMBER 30, MITOCHONDRIAL chaperone#PC00072 IXOSC|EnsemblGenome=LOC120844095|UniProtKB=A0ACM8EXX7 A0ACM8EXX7 LOC120844095 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC121835932|UniProtKB=A0ACM8FX75 A0ACM8FX75 LOC121835932 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8023297|UniProtKB=A0ACM8EQI8 A0ACM8EQI8 LOC8023297 PTHR42693:SF47 ARYLSULFATASE FAMILY MEMBER N-ACETYLGALACTOSAMINE-6-SULFATASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121836462|UniProtKB=A0ACM8FZP8 A0ACM8FZP8 LOC121836462 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8032980|UniProtKB=A0ACM8F4H7 A0ACM8F4H7 LOC8032980 PTHR45793:SF5 HOMEOBOX PROTEIN HOMEOTIC PROTEIN OCELLILESS transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 cell fate specification#GO:0001708;neuron differentiation#GO:0030182;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;neuron fate commitment#GO:0048663;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;cell fate commitment#GO:0045165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8050512|UniProtKB=A0ACM8DLA1 A0ACM8DLA1 LOC8050512 PTHR21528:SF0 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT NUS1 catalytic activity#GO:0003824;transferase activity#GO:0016740;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycoprotein metabolic process#GO:0009100;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;protein metabolic process#GO:0019538 organelle membrane#GO:0031090;transferase complex#GO:1990234;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121834145|UniProtKB=A0ACM8FMX0 A0ACM8FMX0 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC115327728|UniProtKB=A0ACM8F031 A0ACM8F031 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121835113|UniProtKB=A0ACM8FTG1 A0ACM8FTG1 LOC121835113 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115329958|UniProtKB=A0ACM8EA63 A0ACM8EA63 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;fucosyltransferase activity#GO:0008417;glycosyltransferase activity#GO:0016757 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=LOC115330889|UniProtKB=A0ACM8ESC6 A0ACM8ESC6 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8040860|UniProtKB=A0ACM8DY70 A0ACM8DY70 Ca-alpha1T PTHR45628:SF22 VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1 VOLTAGE-DEPENDENT T-TYPE CALCIUM CHANNEL SUBUNIT ALPHA channel activity#GO:0015267;voltage-gated calcium channel activity#GO:0005245;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;voltage-gated channel activity#GO:0022832;transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075 transport#GO:0006810;inorganic cation import across plasma membrane#GO:0098659;calcium ion transport#GO:0006816;import into cell#GO:0098657;calcium ion transmembrane import into cytosol#GO:0097553;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;calcium ion import#GO:0070509;calcium ion transmembrane transport#GO:0070588;inorganic ion import across plasma membrane#GO:0099587;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739 voltage-gated calcium channel complex#GO:0005891;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;calcium channel complex#GO:0034704;cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cation channel complex#GO:0034703;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC115326008|UniProtKB=A0ACM8FFM1 A0ACM8FFM1 LOC115326008 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC120842297|UniProtKB=A0ACM8EUI6 A0ACM8EUI6 LOC120842297 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115331332|UniProtKB=A0ACM8F3D9 A0ACM8F3D9 LOC115331332 PTHR24256:SF575 TRYPTASE-RELATED LD47230P-RELATED serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8024927|UniProtKB=A0ACM8DIT4 A0ACM8DIT4 LOC8024927 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8030416|UniProtKB=A0ACM8DS14 A0ACM8DS14 PTHR46089:SF2 ALSIN HOMOLOG ALSIN HOMOLOG molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme binding#GO:0019899;guanyl-nucleotide exchange factor activity#GO:0005085;binding#GO:0005488;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121834249|UniProtKB=A0ACM8FPV3 A0ACM8FPV3 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8052408|UniProtKB=A0ACM8FC43 A0ACM8FC43 PTHR45623:SF62 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED KISMET, ISOFORM C nucleic acid binding#GO:0003676;chromatin binding#GO:0003682;hydrolase activity#GO:0016787;DNA binding#GO:0003677;ATP hydrolysis activity#GO:0016887;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;histone binding#GO:0042393;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097 regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8035152|UniProtKB=A0ACM8FY30 A0ACM8FY30 LOC8035152 PTHR33332:SF55 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8052596|UniProtKB=A0ACM8E464 A0ACM8E464 LOC8052596 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC115308586|UniProtKB=A0ACM8EP29 A0ACM8EP29 ArfGAP1 PTHR46395:SF1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 ADP-RIBOSYLATION FACTOR GTPASE-ACTIVATING PROTEIN 1 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 regulation of intracellular signal transduction#GO:1902531;regulation of endocytosis#GO:0030100;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of biological process#GO:0050789;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 GTPase-activating protein#PC00257;G-protein modulator#PC00022 Integrin signalling pathway#P00034>ASAP1#P00909 IXOSC|EnsemblGenome=LOC8053092|UniProtKB=A0ACM8DLK9 A0ACM8DLK9 l(3)72Ab PTHR24075:SF5 SEC63 DOMAIN-CONTAINING U5 SMALL NUCLEAR RIBONUCLEOPROTEIN 200 KDA HELICASE RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187 ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115319607|UniProtKB=A0ACM8E042 A0ACM8E042 LOC115319607 PTHR45999:SF4 UNC-13-4A, ISOFORM B UNC-13-4A, ISOFORM B IXOSC|EnsemblGenome=LOC115311700|UniProtKB=A0ACM8F5E9 A0ACM8F5E9 LOC115311700 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115330743|UniProtKB=A0ACM8EC72 A0ACM8EC72 vib PTHR10658:SF11 PHOSPHATIDYLINOSITOL TRANSFER PROTEIN VIBRATOR, ISOFORM B transporter#PC00227 IXOSC|EnsemblGenome=LOC8051761|UniProtKB=A0ACM8DXQ4 A0ACM8DXQ4 LOC8051761 PTHR45998:SF9 SERINE/THREONINE-PROTEIN KINASE 16 SERINE_THREONINE-PROTEIN KINASE 16 protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8028569|UniProtKB=A0ACM8EBV6 A0ACM8EBV6 LOC8028569 PTHR13422:SF12 SIN3-HDAC COMPLEX-ASSOCIATED FACTOR SIN3-HDAC COMPLEX-ASSOCIATED FACTOR regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of locomotion#GO:0040013;negative regulation of cell motility#GO:2000146;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cellular process#GO:0050794;regulation of cell migration#GO:0030334;negative regulation of cell migration#GO:0030336;negative regulation of cellular process#GO:0048523;regulation of cell motility#GO:2000145 protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;Sin3-type complex#GO:0070822;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115314897|UniProtKB=A0ACM8EJP1 A0ACM8EJP1 LOC115314897 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115310952|UniProtKB=A0ACM8EEM1 A0ACM8EEM1 LOC115310952 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115315958|UniProtKB=A0ACM8EVG4 A0ACM8EVG4 LOC115315958 PTHR18945:SF908 NEUROTRANSMITTER GATED ION CHANNEL HISTAMINE-GATED CHLORIDE CHANNEL ALPHA1 SUBUNIT monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC120843762|UniProtKB=A0ACM8G7C3 A0ACM8G7C3 LOC120843762 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051037|UniProtKB=A0ACM8EAT0 A0ACM8EAT0 LOC8051037 PTHR23507:SF1 ZGC:174356 FI18259P1-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569 IXOSC|EnsemblGenome=LOC120839844|UniProtKB=A0ACM8G8J8 A0ACM8G8J8 LOC120839844 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046763|UniProtKB=A0ACM8FFS2 A0ACM8FFS2 LOC121046763 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115312783|UniProtKB=A0ACM8ER59 A0ACM8ER59 LOC115312783 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120846061|UniProtKB=A0ACM8F0P6 A0ACM8F0P6 LOC120846061 PTHR45656:SF4 PROTEIN CBR-CLEC-78 COMPLEMENT COMPONENT RECEPTOR 1-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8035964|UniProtKB=A0ACM8FC25 A0ACM8FC25 LOC8035964 PTHR43895:SF164 CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE-RELATED CALCIUM_CALMODULIN-DEPENDENT PROTEIN KINASE KINASE catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;biological regulation#GO:0065007;signaling#GO:0023052;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 IXOSC|EnsemblGenome=LOC8042477|UniProtKB=A0ACM8E100 A0ACM8E100 LOC8042477 PTHR12317:SF0 DIACYLGLYCEROL O-ACYLTRANSFERASE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 neutral lipid metabolic process#GO:0006638;lipid metabolic process#GO:0006629;triglyceride metabolic process#GO:0006641;acylglycerol metabolic process#GO:0006639;metabolic process#GO:0008152;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;triglyceride biosynthetic process#GO:0019432;glycerolipid metabolic process#GO:0046486;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC115318905|UniProtKB=A0ACM8G082 A0ACM8G082 LOC115318905 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120846793|UniProtKB=A0ACM8F2F7 A0ACM8F2F7 LOC120846793 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;purine-containing compound catabolic process#GO:0072523;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate catabolic process#GO:1901292;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;purine nucleotide catabolic process#GO:0006195;ribonucleotide metabolic process#GO:0009259;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 hydrolase#PC00121;phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC120844177|UniProtKB=A0ACM8EY20 A0ACM8EY20 LOC120844177 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120843271|UniProtKB=A0ACM8EVR3 A0ACM8EVR3 LOC120843271 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051102|UniProtKB=A0ACM8EB27 A0ACM8EB27 LOC8051102 PTHR22734:SF3 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 RIBOSOME PRODUCTION FACTOR 1 binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;nucleic acid biosynthetic process#GO:0141187;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;preribosome, large subunit precursor#GO:0030687;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8024124|UniProtKB=A0ACM8DHY5 A0ACM8DHY5 LOC8024124 PTHR12315:SF1 BICOID-INTERACTING PROTEIN RELATED RNA 5'-MONOPHOSPHATE METHYLTRANSFERASE O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;RNA methyltransferase activity#GO:0008173;catalytic activity, acting on RNA#GO:0140098 positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of gene silencing by regulatory ncRNA#GO:0060966;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of biological process#GO:0048518;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of macromolecule metabolic process#GO:0010604 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115308361|UniProtKB=A0ACM8DMB7 A0ACM8DMB7 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329552|UniProtKB=A0ACM8G2H6 A0ACM8G2H6 LOC115329552 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291 sodium ion transport#GO:0006814;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8028983|UniProtKB=A0ACM8E357 A0ACM8E357 LOC8028983 PTHR22984:SF33 SERINE/THREONINE-PROTEIN KINASE PIM SERINE_THREONINE-PROTEIN KINASE 1 catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 negative regulation of programmed cell death#GO:0043069;regulation of biological process#GO:0050789;regulation of mitotic cell cycle#GO:0007346;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of cell cycle#GO:0051726;biological regulation#GO:0065007;negative regulation of apoptotic process#GO:0043066;regulation of cellular process#GO:0050794;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8026600|UniProtKB=A0ACM8E695 A0ACM8E695 LOC8026600 PTHR11675:SF143 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 3 polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;catalytic activity, acting on a protein#GO:0140096;UDP-glycosyltransferase activity#GO:0008194;acetylgalactosaminyltransferase activity#GO:0008376;glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8039346|UniProtKB=A0ACM8E1W1 A0ACM8E1W1 LOC8039346 PTHR46047:SF3 TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 61F phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;kinase binding#GO:0019900;binding#GO:0005488;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787;protein binding#GO:0005515 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of MAPK cascade#GO:0043409;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cellular process#GO:0050794;regulation of MAPK cascade#GO:0043408;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of ERK1 and ERK2 cascade#GO:0070373;regulation of ERK1 and ERK2 cascade#GO:0070372;negative regulation of response to stimulus#GO:0048585 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115325521|UniProtKB=A0ACM8EQF6 A0ACM8EQF6 LOC115325521 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8039337|UniProtKB=A0ACM8EDX9 A0ACM8EDX9 Faf2 PTHR23322:SF1 FAS-ASSOCIATED PROTEIN FAS-ASSOCIATED FACTOR 2 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120845796|UniProtKB=A0ACM8F1S1 A0ACM8F1S1 LOC120845796 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023937|UniProtKB=A0ACM8DMF9 A0ACM8DMF9 LOC8023937 PTHR45915:SF9 TRANSCRIPTION INTERMEDIARY FACTOR TOUTATIS, ISOFORM E transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ISWI-type complex#GO:0031010;nucleus#GO:0005634;chromatin#GO:0000785;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8037014|UniProtKB=A0ACM8E8M9 A0ACM8E8M9 LOC8037014 PTHR11712:SF362 POLYKETIDE SYNTHASE-RELATED 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330 IXOSC|EnsemblGenome=LOC8027630|UniProtKB=A0ACM8G111 A0ACM8G111 LOC8027630 PTHR44755:SF8 NATRIURETIC PEPTIDE RECEPTOR 3-RELATED RECEPTOR LIGAND BINDING REGION DOMAIN-CONTAINING PROTEIN peptide hormone binding#GO:0017046;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;hormone binding#GO:0042562;binding#GO:0005488 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8031557|UniProtKB=A0ACM8DID5 A0ACM8DID5 LOC8031557 PTHR31551:SF1 PRE-MRNA-SPLICING FACTOR CWF18 COILED-COIL DOMAIN-CONTAINING PROTEIN 12 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;post-mRNA release spliceosomal complex#GO:0071014;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC115316758|UniProtKB=A0ACM8DWC8 A0ACM8DWC8 LOC115316758 PTHR21359:SF1 DUF5577 DOMAIN-CONTAINING PROTEIN DUF5577 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324092|UniProtKB=A0ACM8E6F6 A0ACM8E6F6 LOC115326113 PTHR33936:SF24 PROTEIN CBG17840 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030226|UniProtKB=A0ACM8DGH3 A0ACM8DGH3 LOC8030226 PTHR21669:SF28 CAPZ-INTERACTING PROTEIN AND RELATED PROTEINS YEMANUCLEIN cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8052705|UniProtKB=A0ACM8EG50 A0ACM8EG50 LOC8052705 PTHR31800:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 COILED-COIL DOMAIN-CONTAINING PROTEIN 32 plasma membrane bounded cell projection organization#GO:0120036;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cell projection organization#GO:0030030;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 IXOSC|EnsemblGenome=LOC121838227|UniProtKB=A0ACM8G878 A0ACM8G878 LOC121838227 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047329|UniProtKB=A0ACM8G7F0 A0ACM8G7F0 LOC121047329 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC120844199|UniProtKB=A0ACM8EY64 A0ACM8EY64 LOC120844199 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8034703|UniProtKB=A0ACM8E9M0 A0ACM8E9M0 PTHR43655:SF2 ATP-DEPENDENT PROTEASE AFG3 LIKE MATRIX AAA PEPTIDASE SUBUNIT 2, ISOFORM A metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120851150|UniProtKB=A0ACM8FA61 A0ACM8FA61 LOC120851150 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887;heart development#GO:0007507;circulatory system development#GO:0072359;animal gross anatomical part developmental process#GO:0160108;post-embryonic development#GO:0009791;cell adhesion#GO:0007155;developmental process#GO:0032502;anatomical structure development#GO:0048856;animal organ development#GO:0048513;multicellular organism development#GO:0007275;system development#GO:0048731 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 IXOSC|EnsemblGenome=LOC115308338|UniProtKB=A0ACM8DMD7 A0ACM8DMD7 LOC115308338 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120838363|UniProtKB=A0ACM8EKN0 A0ACM8EKN0 LOC120838363 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8053856|UniProtKB=A0ACM8E2C1 A0ACM8E2C1 RpS6 PTHR11502:SF6 40S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN ES6 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8028088|UniProtKB=A0ACM8E3B2 A0ACM8E3B2 LOC8028088 PTHR24060:SF136 METABOTROPIC GLUTAMATE RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 3 PROFILE DOMAIN-CONTAINING PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;glutamate receptor activity#GO:0008066;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640 cell surface receptor signaling pathway#GO:0007166;signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;G protein-coupled receptor signaling pathway#GO:0007186;glutamate receptor signaling pathway#GO:0007215;regulation of synaptic transmission, glutamatergic#GO:0051966;cell communication#GO:0007154;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 cell junction#GO:0030054;synaptic membrane#GO:0097060;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;cell periphery#GO:0071944;membrane#GO:0016020;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;organelle#GO:0043226;asymmetric synapse#GO:0032279;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8038010|UniProtKB=A0ACM8FWX4 A0ACM8FWX4 LOC8038010 PTHR14139:SF2 CALSYNTENIN CALSYNTENIN-1 binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;cell-cell adhesion mediator activity#GO:0098632 regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;positive regulation of multicellular organismal process#GO:0051240;regulation of developmental process#GO:0050793;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;positive regulation of nervous system development#GO:0051962;regulation of cellular process#GO:0050794;positive regulation of cellular component organization#GO:0051130;cell adhesion#GO:0007155;regulation of cell junction assembly#GO:1901888;regulation of synapse organization#GO:0050807;regulation of biological quality#GO:0065008;regulation of synapse structure or activity#GO:0050803;regulation of nervous system development#GO:0051960;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;regulation of multicellular organismal process#GO:0051239;regulation of synapse assembly#GO:0051963;positive regulation of cellular component biogenesis#GO:0044089;positive regulation of developmental process#GO:0051094;positive regulation of synapse assembly#GO:0051965 postsynaptic density membrane#GO:0098839;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;asymmetric synapse#GO:0032279;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;postsynapse#GO:0098794;cell junction#GO:0030054;synaptic membrane#GO:0097060;cell surface#GO:0009986;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115326716|UniProtKB=A0ACM8E798 A0ACM8E798 Tomosyn PTHR10241:SF25 LETHAL 2 GIANT LARVAE PROTEIN TOMOSYN, ISOFORM C cytoskeletal protein binding#GO:0008092;myosin binding#GO:0017022;SNARE binding#GO:0000149;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;binding#GO:0005488;syntaxin binding#GO:0019905;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 cellular process#GO:0009987;export from cell#GO:0140352;Golgi to plasma membrane transport#GO:0006893;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;Golgi vesicle transport#GO:0048193;transport#GO:0006810;secretion by cell#GO:0032940;vesicle-mediated transport to the plasma membrane#GO:0098876;post-Golgi vesicle-mediated transport#GO:0006892;exocytosis#GO:0006887;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;cellular localization#GO:0051641 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC115315097|UniProtKB=A0ACM8ESV6 A0ACM8ESV6 LOC115323795 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115323788|UniProtKB=A0ACM8E3Z2 A0ACM8E3Z2 LOC115323788 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC121836430|UniProtKB=A0ACM8FY59 A0ACM8FY59 LOC121836430 PTHR45080:SF8 CONTACTIN 5 NEURAL CELL ADHESION MOLECULE 1 ISOFORM X1 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;cell junction organization#GO:0034330;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;cell projection#GO:0042995;neuronal cell body#GO:0043025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell body#GO:0044297;cell periphery#GO:0071944;axon#GO:0030424 IXOSC|EnsemblGenome=LOC115325462|UniProtKB=A0ACM8E4U0 A0ACM8E4U0 Prosbeta6 PTHR32194:SF2 METALLOPROTEASE TLDD PROTEASOME SUBUNIT BETA TYPE-1 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;proteasome complex#GO:0000502;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peptidase complex#GO:1905368;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 metalloprotease#PC00153 Parkinson disease#P00049>20S proteasome#P01227 IXOSC|EnsemblGenome=LOC8033671|UniProtKB=A0ACM8DVI0 A0ACM8DVI0 sud1 PTHR12117:SF0 HISTONE ACETYLTRANSFERASE COMPLEX PROLYL 3-HYDROXYLASE OGFOD1 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of protein-containing complex disassembly#GO:0043244;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular component organization#GO:0051128;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chromatin/chromatin-binding, or -regulatory protein#PC00077;histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC121833995|UniProtKB=A0ACM8FPU1 A0ACM8FPU1 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034916|UniProtKB=A0ACM8DYT8 A0ACM8DYT8 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120839648|UniProtKB=A0ACM8ELN7 A0ACM8ELN7 LOC120839648 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038280|UniProtKB=A0ACM8EHT8 A0ACM8EHT8 LOC8038280 PTHR10264:SF134 BAND 7 PROTEIN-RELATED BAND 7 DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC115318365|UniProtKB=A0ACM8ELC7 A0ACM8ELC7 LOC115318365 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115323494|UniProtKB=A0ACM8F9M2 A0ACM8F9M2 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8037271|UniProtKB=A0ACM8EXD6 A0ACM8EXD6 LOC8037271 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8035314|UniProtKB=A0ACM8DJQ2 A0ACM8DJQ2 LOC8035314 PTHR12205:SF0 CENTROMERE/KINETOCHORE PROTEIN ZW10 CENTROMERE_KINETOCHORE PROTEIN ZW10 HOMOLOG negative regulation of chromosome organization#GO:2001251;cell communication#GO:0007154;localization#GO:0051179;organelle fission#GO:0048285;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular signal transduction#GO:0035556;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;regulation of chromosome organization#GO:0033044;negative regulation of cell cycle process#GO:0010948;regulation of mitotic sister chromatid separation#GO:0010965;establishment of localization#GO:0051234;regulation of mitotic nuclear division#GO:0007088;mitotic sister chromatid segregation#GO:0000070;regulation of mitotic cell cycle#GO:0007346;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;Golgi vesicle transport#GO:0048193;negative regulation of cell cycle#GO:0045786;mitotic spindle assembly checkpoint signaling#GO:0007094;cell cycle checkpoint signaling#GO:0000075;regulation of cell cycle process#GO:0010564;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;chromosome organization#GO:0051276;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;nuclear division#GO:0000280;cellular localization#GO:0051641;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of mitotic sister chromatid segregation#GO:0033048;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046;establishment of localization in cell#GO:0051649;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of chromosome separation#GO:1905818;negative regulation of mitotic cell cycle phase transition#GO:1901991;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;kinetochore#GO:0000776;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;endoplasmic reticulum protein-containing complex#GO:0140534;vesicle tethering complex#GO:0099023;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC120840275|UniProtKB=A0ACM8EP24 A0ACM8EP24 LOC120840275 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115325136|UniProtKB=A0ACM8F267 A0ACM8F267 LOC115325136 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120837666|UniProtKB=A0ACM8EIY9 A0ACM8EIY9 LOC120837666 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8035254|UniProtKB=A0ACM8FWJ9 A0ACM8FWJ9 LOC8035254 PTHR46925:SF5 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8040029|UniProtKB=A0ACM8FAR8 A0ACM8FAR8 PTHR32059:SF2 RAB11-BINDING PROTEIN RELCH RAB11-BINDING PROTEIN RELCH establishment of localization#GO:0051234;cellular localization#GO:0051641;sterol transport#GO:0015918;localization#GO:0051179;organic hydroxy compound transport#GO:0015850;intracellular transport#GO:0046907;lipid localization#GO:0010876;transport#GO:0006810;lipid transport#GO:0006869;intracellular sterol transport#GO:0032366;cholesterol transport#GO:0030301;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037 IXOSC|EnsemblGenome=LOC8024767|UniProtKB=A0ACM8FDW7 A0ACM8FDW7 LOC8024767 PTHR11375:SF0 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 ACIDIC LEUCINE-RICH NUCLEAR PHOSPHOPROTEIN 32 FAMILY MEMBER A histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121836709|UniProtKB=A0ACM8FZF2 A0ACM8FZF2 LOC121836709 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040825|UniProtKB=A0ACM8FNE0 A0ACM8FNE0 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 IXOSC|EnsemblGenome=LOC8053997|UniProtKB=A0ACM8FFZ2 A0ACM8FFZ2 ash1 PTHR46147:SF3 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 HISTONE-LYSINE N-METHYLTRANSFERASE ASH1 catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;histone H3K4 methyltransferase activity#GO:0042800;lysine N-methyltransferase activity#GO:0016278;histone H3 methyltransferase activity#GO:0140938;histone modifying activity#GO:0140993;histone methyltransferase activity#GO:0042054;protein-lysine N-methyltransferase activity#GO:0016279;N-methyltransferase activity#GO:0008170;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 histone modifying enzyme#PC00261;chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8026660|UniProtKB=A0ACM8DI44 A0ACM8DI44 Fnta PTHR11129:SF1 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT PROTEIN FARNESYLTRANSFERASE_GERANYLGERANYLTRANSFERASE TYPE-1 SUBUNIT ALPHA transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 catalytic complex#GO:1902494;transferase complex#GO:1990234;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120849053|UniProtKB=A0ACM8F6V7 A0ACM8F6V7 PTHR12234:SF0 FORMIMINOTRANSFERASE-CYCLODEAMINASE FORMIMIDOYLTRANSFERASE-CYCLODEAMINASE lyase activity#GO:0016829;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120850667|UniProtKB=A0ACM8F9D3 A0ACM8F9D3 LOC120850667 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043244|UniProtKB=A0ACM8E9T6 A0ACM8E9T6 RpL13 PTHR11722:SF0 60S RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN EL13 structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;structural constituent of ribosome#GO:0003735;nucleic acid binding#GO:0003676 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8025890|UniProtKB=A0ACM8DGM6 A0ACM8DGM6 LOC8025890 PTHR22978:SF44 B-CELL TRANSLOCATION GENE PROTEIN BTG3-LIKE PROTEIN organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8039361|UniProtKB=A0ACM8EPM3 A0ACM8EPM3 LOC8039361 PTHR47767:SF3 ADHESION G PROTEIN-COUPLED RECEPTOR G7 ADHESION G PROTEIN-COUPLED RECEPTOR E2 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115332589|UniProtKB=A0ACM8EER8 A0ACM8EER8 LOC115332589 PTHR24406:SF26 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120843626|UniProtKB=A0ACM8EWM1 A0ACM8EWM1 LOC120843626 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120837965|UniProtKB=A0ACM8G2G0 A0ACM8G2G0 LOC120837965 PTHR13856:SF137 VHS DOMAIN CONTAINING PROTEIN FAMILY GH05942P protein binding#GO:0005515;clathrin binding#GO:0030276;binding#GO:0005488 cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 membrane#GO:0016020;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8034948|UniProtKB=A0ACM8EXY8 A0ACM8EXY8 LOC8034948 PTHR23199:SF19 NEUROTROPHIN 1-RELATED SPAETZLE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;molecular function activator activity#GO:0140677;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545 nervous system development#GO:0007399;response to other organism#GO:0051707;multicellular organismal process#GO:0032501;defense response to other organism#GO:0098542;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;anatomical structure formation involved in morphogenesis#GO:0048646;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;multicellular organism development#GO:0007275;developmental process#GO:0032502;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;response to stimulus#GO:0050896;central nervous system development#GO:0007417;anatomical structure morphogenesis#GO:0009653;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC121837158|UniProtKB=A0ACM8G258 A0ACM8G258 LOC121837158 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120841220|UniProtKB=A0ACM8EQT8 A0ACM8EQT8 LOC120841220 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120848457|UniProtKB=A0ACM8F5T6 A0ACM8F5T6 LOC120848457 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837173|UniProtKB=A0ACM8G3K2 A0ACM8G3K2 LOC121837173 PTHR46331:SF2 VALACYCLOVIR HYDROLASE SERINE HYDROLASE BPHL catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8030988|UniProtKB=A0ACM8FYN4 A0ACM8FYN4 LOC8030988 PTHR11267:SF181 T-BOX PROTEIN-RELATED OPTOMOTOR-BLIND PROTEIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 IXOSC|EnsemblGenome=LOC8036703|UniProtKB=A0ACM8FYW3 A0ACM8FYW3 tll PTHR24083:SF189 NUCLEAR HORMONE RECEPTOR PROTEIN TAILLESS nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8043983|UniProtKB=A0ACM8DUL2 A0ACM8DUL2 LOC8043983 PTHR45867:SF3 PURPLE ACID PHOSPHATASE ACID PHOSPHATASE TYPE 7 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115310104|UniProtKB=A0ACM8G1J2 A0ACM8G1J2 LOC115310104 PTHR22880:SF225 FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS HOMEOTIC PROTEIN FEMALE STERILE-RELATED histone reader activity#GO:0140566;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;chromatin-protein adaptor activity#GO:0140463 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8024071|UniProtKB=A0ACM8DV92 A0ACM8DV92 LOC8024071 PTHR22903:SF8 PLEKHH PROTEIN PH DOMAIN-CONTAINING PROTEIN Axon guidance mediated by netrin#P00009>MAX-1#P00365 IXOSC|EnsemblGenome=LOC8025952|UniProtKB=A0ACM8DGV3 A0ACM8DGV3 LOC8025952 PTHR11247:SF81 PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 PALMITOYL-PROTEIN THIOESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity, acting on a protein#GO:0140096;palmitoyl hydrolase activity#GO:0098599;hydrolase activity#GO:0016787 system development#GO:0048731;import into cell#GO:0098657;anatomical structure development#GO:0048856;establishment of localization#GO:0051234;multicellular organism development#GO:0007275;localization#GO:0051179;transport#GO:0006810;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;endocytosis#GO:0006897;multicellular organismal process#GO:0032501 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115311228|UniProtKB=A0ACM8EL37 A0ACM8EL37 LOC115311228 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115322773|UniProtKB=A0ACM8EI48 A0ACM8EI48 LOC115322773 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120846323|UniProtKB=A0ACM8F230 A0ACM8F230 LOC120846323 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8030972|UniProtKB=A0ACM8EC77 A0ACM8EC77 LOC8030972 PTHR10699:SF11 NEUROMODULIN IGLOO, ISOFORM A protein binding#GO:0005515;binding#GO:0005488;calmodulin binding#GO:0005516 IXOSC|EnsemblGenome=LOC121838486|UniProtKB=A0ACM8G941 A0ACM8G941 LOC121838486 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842095|UniProtKB=A0ACM8ET18 A0ACM8ET18 LOC120842095 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8035826|UniProtKB=A0ACM8E1H2 A0ACM8E1H2 LOC8035826 PTHR13808:SF1 CBP/P300-RELATED HISTONE ACETYLTRANSFERASE protein N-acetyltransferase activity#GO:0034212;transcription coactivator activity#GO:0003713;transferase activity#GO:0016740;protein N-acyltransferase activity#GO:0140186;histone modifying activity#GO:0140993;acetyltransferase activity#GO:0016407;binding#GO:0005488;transcription regulator activity#GO:0140110;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712;chromatin DNA binding#GO:0031490;DNA binding#GO:0003677;histone acetyltransferase activity#GO:0004402;nucleic acid binding#GO:0003676;protein-lysine-acetyltransferase activity#GO:0061733;acyltransferase activity#GO:0016746;chromatin binding#GO:0003682;N-acetyltransferase activity#GO:0008080 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;transcription regulator complex#GO:0005667;membraneless organelle#GO:0043228;transferase complex#GO:1990234;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785 histone modifying enzyme#PC00261 Wnt signaling pathway#P00057>CBP#P01448;BMP/activin signaling pathway-drosophila#P06211>NEJ#P06246;DPP-SCW signaling pathway#P06212>NEJ#P06260;p53 pathway#P00059>CBP#P04623;Huntington disease#P00029>CBP#P00777;TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;DPP signaling pathway#P06213>NEJ#P06284;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>CREB#P00713;SCW signaling pathway#P06216>NEJ#P06328;GBB signaling pathway#P06214>NEJ#P06295 IXOSC|EnsemblGenome=LOC8029842|UniProtKB=A0ACM8DMV5 A0ACM8DMV5 LOC8029842 PTHR11223:SF2 EXPORTIN 1/5 EXPORTIN-1 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;ribosomal subunit export from nucleus#GO:0000054;intracellular transport#GO:0046907;transport#GO:0006810;cellular component biogenesis#GO:0044085;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;ribosome biogenesis#GO:0042254;organelle localization#GO:0051640;ribosome localization#GO:0033750;nucleocytoplasmic transport#GO:0006913;ribosomal small subunit export from nucleus#GO:0000056;establishment of organelle localization#GO:0051656;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit export from nucleus#GO:0000055 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115313091|UniProtKB=A0ACM8DSM5 A0ACM8DSM5 LOC115313091 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8038783|UniProtKB=A0ACM8G3E5 A0ACM8G3E5 LOC8038783 PTHR19290:SF102 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED TRANSCRIPTION FACTOR ATOH8 RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;sensory organ development#GO:0007423;developmental process#GO:0032502;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC120839972|UniProtKB=A0ACM8G6G6 A0ACM8G6G6 LOC120839972 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8043918|UniProtKB=A0ACM8FA16 A0ACM8FA16 LOC8043918 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8051600|UniProtKB=A0ACM8EN97 A0ACM8EN97 LOC8051600 PTHR37402:SF1 GRAM DOMAIN-CONTAINING PROTEIN 4 GRAM DOMAIN-CONTAINING PROTEIN 4 negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of apoptotic process#GO:0042981;positive regulation of apoptotic process#GO:0043065;regulation of innate immune response#GO:0045088;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of response to external stimulus#GO:0032101;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;negative regulation of immune system process#GO:0002683;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of immune response#GO:0050776;regulation of signaling#GO:0023051;regulation of defense response#GO:0031347;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;positive regulation of programmed cell death#GO:0043068;regulation of cell communication#GO:0010646;regulation of response to biotic stimulus#GO:0002831 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8033846|UniProtKB=A0ACM8DN53 A0ACM8DN53 LOC8033846 PTHR11070:SF30 UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER F-BOX DNA HELICASE 1 ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;3'-5' DNA helicase activity#GO:0043138;isomerase activity#GO:0016853 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;DNA-templated DNA replication#GO:0006261;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8023401|UniProtKB=A0ACM8E9L1 A0ACM8E9L1 LOC8023401 PTHR21315:SF2 APRATAXIN AND PNK-LIKE FACTOR-RELATED APRATAXIN AND PNK-LIKE FACTOR catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896 site of double-strand break#GO:0035861;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115316590|UniProtKB=A0ACM8DW20 A0ACM8DW20 Herc4 PTHR45622:SF76 UBIQUITIN-PROTEIN LIGASE E3A-RELATED HECT AND RLD DOMAIN CONTAINING E3 UBIQUITIN LIGASE 4, ISOFORM C ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121046339|UniProtKB=A0ACM8FDX2 A0ACM8FDX2 LOC121046339 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836331|UniProtKB=A0ACM8F735 A0ACM8F735 LOC120836331 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC121045838|UniProtKB=A0ACM8FC70 A0ACM8FC70 LOC121045838 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120850682|UniProtKB=A0ACM8FWB5 A0ACM8FWB5 LOC120850682 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8039398|UniProtKB=A0ACM8ECG7 A0ACM8ECG7 LOC8039398 PTHR20933:SF3 F-BOX ONLY PROTEIN 33 F-BOX ONLY PROTEIN 33 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of protein modification by small protein conjugation or removal#GO:1903320;positive regulation of metabolic process#GO:0009893;regulation of post-translational protein modification#GO:1901873;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of protein modification process#GO:0031399;regulation of protein ubiquitination#GO:0031396 IXOSC|EnsemblGenome=LOC8041194|UniProtKB=A0ACM8E6I5 A0ACM8E6I5 LOC8041194 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121048575|UniProtKB=A0ACM8FNC4 A0ACM8FNC4 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8035800|UniProtKB=A0ACM8DMB1 A0ACM8DMB1 IntS14 PTHR13532:SF3 FAMILY NOT NAMED INTEGRATOR COMPLEX SUBUNIT 14 IXOSC|EnsemblGenome=LOC8035879|UniProtKB=A0ACM8FKC5 A0ACM8FKC5 LOC8035879 PTHR45635:SF14 ADP,ATP CARRIER PROTEIN 1-RELATED-RELATED ADP_ATP TRANSLOCASE active transmembrane transporter activity#GO:0022804;purine nucleotide transmembrane transporter activity#GO:0015216;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297;carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932 nitrogen compound transport#GO:0071705;carbohydrate derivative transport#GO:1901264;cellular process#GO:0009987;nucleobase-containing compound transport#GO:0015931;regulation of membrane permeability#GO:0090559;organophosphate ester transport#GO:0015748;regulation of mitochondrial membrane permeability#GO:0046902;biological regulation#GO:0065007;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of biological quality#GO:0065008 organelle membrane#GO:0031090;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8052272|UniProtKB=A0ACM8DM28 A0ACM8DM28 LOC8052272 PTHR43612:SF3 TRIFUNCTIONAL ENZYME SUBUNIT ALPHA TRIFUNCTIONAL ENZYME SUBUNIT ALPHA, MITOCHONDRIAL oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;transferase complex#GO:1990234;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8034128|UniProtKB=A0ACM8EC43 A0ACM8EC43 LOC8034128 PTHR23325:SF1 SERUM RESPONSE FACTOR-BINDING SERUM RESPONSE FACTOR-BINDING PROTEIN 1 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;maturation of SSU-rRNA#GO:0030490;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;ribosomal small subunit biogenesis#GO:0042274;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070 ribonucleoprotein complex#GO:1990904;90S preribosome#GO:0030686;preribosome#GO:0030684;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120843479|UniProtKB=A0ACM8EWA9 A0ACM8EWA9 LOC120843479 PTHR11439:SF463 GAG-POL-RELATED RETROTRANSPOSON INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115315384|UniProtKB=A0ACM8DV79 A0ACM8DV79 LOC115315384 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8042302|UniProtKB=A0ACM8G3T8 A0ACM8G3T8 LOC8042302 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310162|UniProtKB=A0ACM8ET56 A0ACM8ET56 LOC115310162 PTHR23065:SF11 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 SYNDAPIN, ISOFORM C phospholipid binding#GO:0005543;binding#GO:0005488;lipid binding#GO:0008289 regulation of endocytosis#GO:0030100;regulation of transport#GO:0051049;regulation of localization#GO:0032879;plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;biological regulation#GO:0065007;membrane organization#GO:0061024;cytoskeleton organization#GO:0007010;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128 membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane#GO:0016020;vesicle#GO:0031982;cell periphery#GO:0071944 actin or actin-binding cytoskeletal protein#PC00041;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120844034|UniProtKB=A0ACM8EYN7 A0ACM8EYN7 LOC120844034 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317160|UniProtKB=A0ACM8DXD7 A0ACM8DXD7 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120850835|UniProtKB=A0ACM8FXX3 A0ACM8FXX3 LOC120850835 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;sodium ion transport#GO:0006814;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8028069|UniProtKB=A0ACM8E2Z8 A0ACM8E2Z8 LOC8028069 PTHR10983:SF24 1-ACYLGLYCEROL-3-PHOSPHATE ACYLTRANSFERASE-RELATED 1-ACYLGLYCEROL-3-PHOSPHATE O-ACYLTRANSFERASE 3, ISOFORM E-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8032401|UniProtKB=A0ACM8FBQ9 A0ACM8FBQ9 LOC8032401 PTHR47965:SF120 ASPARTYL PROTEASE-RELATED BETA-SECRETASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;aspartic-type endopeptidase activity#GO:0004190 biosynthetic process#GO:0009058;membrane protein ectodomain proteolysis#GO:0006509;protein maturation#GO:0051604;gene expression#GO:0010467;membrane protein proteolysis#GO:0033619;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794 protease#PC00190 IXOSC|EnsemblGenome=LOC115317486|UniProtKB=A0ACM8F6D5 A0ACM8F6D5 LOC115317486 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8023418|UniProtKB=A0ACM8F551 A0ACM8F551 PTHR14633:SF3 LITTLE ELONGATION COMPLEX SUBUNIT 2 LITTLE ELONGATION COMPLEX SUBUNIT 2 positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;transcription by RNA polymerase II#GO:0006366;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;snRNA transcription by RNA polymerase II#GO:0042795;nucleic acid metabolic process#GO:0090304;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;snRNA transcription by RNA polymerase III#GO:0042796;snRNA metabolic process#GO:0016073;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;snRNA transcription#GO:0009301;regulation of biological process#GO:0050789;transcription by RNA polymerase III#GO:0006383;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 IXOSC|EnsemblGenome=LOC8033622|UniProtKB=A0ACM8DI53 A0ACM8DI53 Pdhb PTHR11624:SF116 DEHYDROGENASE RELATED PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT BETA, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;oxidoreductase activity#GO:0016491 purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980 acetyltransferase complex#GO:1902493;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115325041|UniProtKB=A0ACM8FKN6 A0ACM8FKN6 LOC115325041 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8042899|UniProtKB=A0ACM8DKZ9 A0ACM8DKZ9 Tsen34 PTHR13070:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34-RELATED TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN34 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;phosphorus-oxygen lyase activity#GO:0016849;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;lyase activity#GO:0016829;catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518 gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031;endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC115314388|UniProtKB=A0ACM8EJN6 A0ACM8EJN6 LOC115314388 PTHR24381:SF486 ZINC FINGER PROTEIN ADULT ENHANCER FACTOR 1-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8053674|UniProtKB=A0ACM8E476 A0ACM8E476 LOC8053674 PTHR22911:SF144 ACYL-MALONYL CONDENSING ENZYME-RELATED SOLUTE CARRIER FAMILY 35 MEMBER G2A-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8036128|UniProtKB=A0ACM8E327 A0ACM8E327 tup PTHR24204:SF8 INSULIN GENE ENHANCER PROTEIN INSULIN GENE ENHANCER PROTEIN ISL-1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;axon development#GO:0061564;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;neuron fate commitment#GO:0048663;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;cell development#GO:0048468;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;axonogenesis#GO:0007409;cell fate commitment#GO:0045165;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;positive regulation of transcription by RNA polymerase II#GO:0045944;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell fate specification#GO:0001708;neuron differentiation#GO:0030182;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115319588|UniProtKB=A0ACM8DZG3 A0ACM8DZG3 LOC115319588 PTHR11544:SF148 COLD SHOCK DOMAIN CONTAINING PROTEINS LD37574P nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121836460|UniProtKB=A0ACM8FYV1 A0ACM8FYV1 LOC121836460 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039583|UniProtKB=A0ACM8DKE2 A0ACM8DKE2 LOC8039583 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120837327|UniProtKB=A0ACM8EGM2 A0ACM8EGM2 LOC120837327 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023162|UniProtKB=A0ACM8DGG8 A0ACM8DGG8 ATPsynF PTHR13080:SF20 ATP SYNTHASE F CHAIN, MITOCHONDRIAL-RELATED ATP SYNTHASE SUBUNIT F, MITOCHONDRIAL-RELATED monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;proton channel activity#GO:0015252;catalytic activity#GO:0003824;proton transmembrane transporter activity#GO:0015078;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;ligase activity#GO:0016874;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933 purine nucleoside triphosphate metabolic process#GO:0009144;primary metabolic process#GO:0044238;proton motive force-driven ATP synthesis#GO:0015986;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;purine nucleoside triphosphate biosynthetic process#GO:0009145;aerobic respiration#GO:0009060;oxidative phosphorylation#GO:0006119;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;generation of precursor metabolites and energy#GO:0006091;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;purine nucleotide metabolic process#GO:0006163;proton motive force-driven mitochondrial ATP synthesis#GO:0042776;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;small molecule metabolic process#GO:0044281;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ATP metabolic process#GO:0046034;ribose phosphate biosynthetic process#GO:0046390;ATP biosynthetic process#GO:0006754;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;ribonucleoside triphosphate biosynthetic process#GO:0009201;carbohydrate derivative biosynthetic process#GO:1901137 transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;catalytic complex#GO:1902494;proton-transporting two-sector ATPase complex#GO:0016469;proton-transporting ATP synthase complex#GO:0045259;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803 ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC115310315|UniProtKB=A0ACM8F298 A0ACM8F298 LOC115310315 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121832845|UniProtKB=A0ACM8FJN0 A0ACM8FJN0 LOC121832845 PTHR24198:SF196 ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN ZU5 DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8036648|UniProtKB=A0ACM8DK04 A0ACM8DK04 LOC8036648 PTHR11351:SF21 ACYL-COA DESATURASE GH07782P-RELATED oxidoreductase activity#GO:0016491;iron ion binding#GO:0005506;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;cation binding#GO:0043169;metal ion binding#GO:0046872;transition metal ion binding#GO:0046914;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;unsaturated fatty acid biosynthetic process#GO:0006636;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;unsaturated fatty acid metabolic process#GO:0033559;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8034264|UniProtKB=A0ACM8DJ61 A0ACM8DJ61 mRpL55 PTHR34095:SF1 39S RIBOSOMAL PROTEIN L55, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML55 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8040147|UniProtKB=A0ACM8F790 A0ACM8F790 LOC8040147 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115320139|UniProtKB=A0ACM8EP66 A0ACM8EP66 LOC115320139 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8025773|UniProtKB=A0ACM8DGE5 A0ACM8DGE5 RpL10 PTHR11726:SF10 60S RIBOSOMAL PROTEIN L10 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8039474|UniProtKB=A0ACM8ED05 A0ACM8ED05 skd PTHR48249:SF3 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 13 transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8032831|UniProtKB=A0ACM8DH07 A0ACM8DH07 LOC8032831 PTHR12170:SF2 MACROPHAGE ERYTHROBLAST ATTACHER-RELATED E3 UBIQUITIN-PROTEIN TRANSFERASE MAEA ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234 IXOSC|EnsemblGenome=LOC120847969|UniProtKB=A0ACM8FQ25 A0ACM8FQ25 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317005|UniProtKB=A0ACM8FQS9 A0ACM8FQS9 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115322970|UniProtKB=A0ACM8EQ27 A0ACM8EQ27 LOC115322970 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115324437|UniProtKB=A0ACM8E3W4 A0ACM8E3W4 LOC115324437 PTHR21556:SF2 TRESLIN TRESLIN chromatin binding#GO:0003682;binding#GO:0005488 mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of DNA replication#GO:0006275;cellular response to stress#GO:0033554;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of DNA metabolic process#GO:0051052;mitotic DNA replication checkpoint signaling#GO:0033314;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;regulation of DNA-templated DNA replication initiation#GO:0030174;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of macromolecule metabolic process#GO:0060255;regulation of DNA-templated DNA replication#GO:0090329;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;DNA damage checkpoint signaling#GO:0000077;mitotic DNA integrity checkpoint signaling#GO:0044774;regulation of mitotic cell cycle#GO:0007346;mitotic G2/M transition checkpoint#GO:0044818;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121836389|UniProtKB=A0ACM8FY14 A0ACM8FY14 LOC121836389 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8051788|UniProtKB=A0ACM8EDW3 A0ACM8EDW3 PTHR21054:SF2 ZINC METALLOPROTEINASE-RELATED MIP04191P metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8023557|UniProtKB=A0ACM8DHA0 A0ACM8DHA0 Rpn9 PTHR10539:SF0 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 13 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;cytoplasm#GO:0005737;cytosol#GO:0005829;proteasome complex#GO:0000502;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369 protein modifying enzyme#PC00260;protease#PC00190 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Parkinson disease#P00049>19S proteasome#P01209 IXOSC|EnsemblGenome=LOC115323585|UniProtKB=A0ACM8E348 A0ACM8E348 LOC115323585 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8042795|UniProtKB=A0ACM8FD52 A0ACM8FD52 kuz PTHR45702:SF2 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 membrane protein ectodomain proteolysis#GO:0006509;membrane protein proteolysis#GO:0033619;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 IXOSC|EnsemblGenome=LOC8051630|UniProtKB=A0ACM8E2U4 A0ACM8E2U4 Spt-I PTHR13693:SF2 CLASS II AMINOTRANSFERASE/8-AMINO-7-OXONONANOATE SYNTHASE SERINE PALMITOYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;palmitoyltransferase activity#GO:0016409 ceramide metabolic process#GO:0006672;sphingoid biosynthetic process#GO:0046520;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;alcohol metabolic process#GO:0006066;ceramide biosynthetic process#GO:0046513;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 transaminase#PC00216 IXOSC|EnsemblGenome=LOC115316518|UniProtKB=A0ACM8F3F8 A0ACM8F3F8 LOC115316518 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042678|UniProtKB=A0ACM8FF45 A0ACM8FF45 LOC8042678 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8040056|UniProtKB=A0ACM8E4V9 A0ACM8E4V9 LOC8040056 PTHR12766:SF11 DEATH DOMAIN-ASSOCIATED PROTEIN 6 DAXX DAXX HISTONE-BINDING DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115332486|UniProtKB=A0ACM8EEM0 A0ACM8EEM0 LOC115332486 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120838159|UniProtKB=A0ACM8EJ54 A0ACM8EJ54 LOC120838159 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848763|UniProtKB=A0ACM8F6F0 A0ACM8F6F0 LOC120848763 PTHR11532:SF96 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE D-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190 IXOSC|EnsemblGenome=LOC8027002|UniProtKB=A0ACM8G8H9 A0ACM8G8H9 LOC8027002 PTHR20852:SF57 GLUTAMINE SYNTHETASE GLUTAMINE SYNTHETASE 2 CYTOPLASMIC ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 proteinogenic amino acid biosynthetic process#GO:0170038;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 ligase#PC00142 Glutamine glutamate conversion#P02745>Glutamine synthase#P04483;Glutamine glutamate conversion#P02745>Glutamine synthetase#P02968 IXOSC|EnsemblGenome=LOC8043285|UniProtKB=A0ACM8DTG1 A0ACM8DTG1 LOC8043285 PTHR12231:SF278 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN DPR-INTERACTING PROTEIN KAPPA, ISOFORM A binding#GO:0005488;cell adhesion mediator activity#GO:0098631;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515 cellular process#GO:0009987;cell adhesion#GO:0007155;synapse organization#GO:0050808;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 cell projection membrane#GO:0031253;cell junction#GO:0030054;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8040819|UniProtKB=A0ACM8EX11 A0ACM8EX11 LOC8040819 PTHR43903:SF30 NEUROLIGIN NEUROLIGIN 3, ISOFORM B signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;protein binding#GO:0005515 cell junction assembly#GO:0034329;cellular component organization#GO:0016043;membrane assembly#GO:0071709;regulation of biological process#GO:0050789;endocytosis#GO:0006897;synapse assembly#GO:0007416;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;regulation of signaling#GO:0023051;cellular localization#GO:0051641;cellular component biogenesis#GO:0044085;synaptic signaling#GO:0099536;cell-cell adhesion#GO:0098609;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;vesicle-mediated transport#GO:0016192;regulation of trans-synaptic signaling#GO:0099177;nervous system development#GO:0007399;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;vesicle-mediated transport in synapse#GO:0099003;import into cell#GO:0098657;synaptic vesicle endocytosis#GO:0048488;chemical synaptic transmission#GO:0007268;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;cell junction organization#GO:0034330;postsynapse organization#GO:0099173;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;trans-synaptic signaling#GO:0099537;synapse organization#GO:0050808;cell communication#GO:0007154;localization#GO:0051179;anatomical structure development#GO:0048856;system development#GO:0048731;multicellular organismal process#GO:0032501;synaptic vesicle recycling#GO:0036465;biological regulation#GO:0065007;membrane organization#GO:0061024;cell-cell signaling#GO:0007267;developmental process#GO:0032502;synaptic vesicle cycle#GO:0099504;transport#GO:0006810;establishment of localization#GO:0051234 synaptic membrane#GO:0097060;postsynaptic membrane#GO:0045211;cell junction#GO:0030054;cell periphery#GO:0071944;postsynapse#GO:0098794;membrane#GO:0016020;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell surface#GO:0009986;plasma membrane region#GO:0098590 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8052000|UniProtKB=A0ACM8E0P9 A0ACM8E0P9 Cln3 PTHR10981:SF0 BATTENIN BATTENIN transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;receptor-mediated endocytosis#GO:0006898;intracellular chemical homeostasis#GO:0055082;vesicle cytoskeletal trafficking#GO:0099518;intracellular transport#GO:0046907;vesicle transport along microtubule#GO:0047496;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;vacuolar transport#GO:0007034;cytoskeleton-dependent intracellular transport#GO:0030705;biological regulation#GO:0065007;vesicle localization#GO:0051648;Golgi to vacuole transport#GO:0006896;localization#GO:0051179;organelle localization#GO:0051640;regulation of pH#GO:0006885;regulation of intracellular pH#GO:0051453;microtubule-based movement#GO:0007018;homeostatic process#GO:0042592;import into cell#GO:0098657;microtubule-based process#GO:0007017;Golgi vesicle transport#GO:0048193;chemical homeostasis#GO:0048878;amino acid transport#GO:0006865;vesicle-mediated transport#GO:0016192;organelle transport along microtubule#GO:0072384;establishment of vesicle localization#GO:0051650;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;post-Golgi vesicle-mediated transport#GO:0006892;lysosomal transport#GO:0007041;microtubule-based transport#GO:0099111;endocytosis#GO:0006897;establishment of organelle localization#GO:0051656;cytosolic transport#GO:0016482;intracellular monoatomic ion homeostasis#GO:0006873 cytoplasm#GO:0005737;vacuole#GO:0005773;late endosome#GO:0005770;endomembrane system#GO:0012505;Golgi apparatus#GO:0005794;lytic vacuole#GO:0000323;lysosome#GO:0005764;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC115330001|UniProtKB=A0ACM8G2S0 A0ACM8G2S0 LOC115330001 PTHR13633:SF3 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 MITOCHONDRIAL TRANSCRIPTION RESCUE FACTOR 1 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC120849538|UniProtKB=A0ACM8F7Y9 A0ACM8F7Y9 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8041731|UniProtKB=A0ACM8E4S9 A0ACM8E4S9 sau PTHR12704:SF2 TRANS-GOLGI PROTEIN GMX33 GOLGI PHOSPHOPROTEIN 3 HOMOLOG SAURON IXOSC|EnsemblGenome=LOC115314854|UniProtKB=A0ACM8EHX1 A0ACM8EHX1 LOC115314854 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313811|UniProtKB=A0ACM8F2S4 A0ACM8F2S4 LOC115313811 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8023683|UniProtKB=A0ACM8FE97 A0ACM8FE97 LOC8023683 PTHR18898:SF8 NUCLEOPROTEIN TPR-RELATED NUCLEOPROTEIN TPR structural molecule activity#GO:0005198;structural constituent of nuclear pore#GO:0017056 metabolic process#GO:0008152;regulation of mitotic spindle assembly#GO:1901673;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;regulation of microtubule cytoskeleton organization#GO:0070507;regulation of cell cycle process#GO:0010564;gene expression#GO:0010467;regulation of mitotic spindle organization#GO:0060236;regulation of spindle assembly#GO:0090169;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component biogenesis#GO:0044087;regulation of cell cycle#GO:0051726;regulation of cellular component organization#GO:0051128;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;regulation of organelle assembly#GO:1902115;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleocytoplasmic transport#GO:0006913;regulation of microtubule-based process#GO:0032886;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleic acid transport#GO:0050657;localization#GO:0051179;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA transport#GO:0050658;RNA localization#GO:0006403;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;regulation of spindle organization#GO:0090224;nucleobase-containing compound transport#GO:0015931 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 primary active transporter#PC00068 Nicotinic acetylcholine receptor signaling pathway#P00044>Myosin#P01097 IXOSC|EnsemblGenome=LOC8041242|UniProtKB=A0ACM8G6P1 A0ACM8G6P1 LOC8041242 PTHR43563:SF26 AMINE OXIDASE AMINE OXIDASE [FLAVIN-CONTAINING] oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 phenol-containing compound metabolic process#GO:0018958;cellular process#GO:0009987;indole-containing compound metabolic process#GO:0042430;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;catabolic process#GO:0009056;amine catabolic process#GO:0009310;metabolic process#GO:0008152;serotonin metabolic process#GO:0042428 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxidase#PC00175 Adrenaline and noradrenaline biosynthesis#P00001>MAO#P00067;Dopamine receptor mediated signaling pathway#P05912>MAO#P05963;5-Hydroxytryptamine degredation#P04372>Monoamine Oxidase#P04401 IXOSC|EnsemblGenome=LOC8033255|UniProtKB=A0ACM8DHK7 A0ACM8DHK7 PTHR31728:SF6 ABRAXAS FAMILY MEMBER BRISC COMPLEX SUBUNIT ABRO1-LIKE PROTEIN microtubule binding#GO:0008017;binding#GO:0005488;modification-dependent protein binding#GO:0140030;polyubiquitin modification-dependent protein binding#GO:0031593;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;protein binding#GO:0005515 organelle localization#GO:0051640;organelle assembly#GO:0070925;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;spindle organization#GO:0007051;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;mitotic sister chromatid segregation#GO:0000070;mitotic spindle assembly#GO:0090307;nuclear division#GO:0000280;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic spindle organization#GO:0007052;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;spindle assembly#GO:0051225;attachment of spindle microtubules to kinetochore#GO:0008608;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120841881|UniProtKB=A0ACM8ESM9 A0ACM8ESM9 LOC120841881 PTHR24373:SF417 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LAMBIK signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8035028|UniProtKB=A0ACM8DPG5 A0ACM8DPG5 PTHR22761:SF10 CHARGED MULTIVESICULAR BODY PROTEIN BCDNA.GH08385-RELATED transport#GO:0006810;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;vesicle organization#GO:0016050;vesicle budding from membrane#GO:0006900;nuclear envelope organization#GO:0006998;endosomal transport#GO:0016197;establishment of localization#GO:0051234;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;multivesicular body sorting pathway#GO:0071985;late endosome to vacuole transport via multivesicular body sorting pathway#GO:0032511;nuclear membrane organization#GO:0071763;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;endosome transport via multivesicular body sorting pathway#GO:0032509;cellular localization#GO:0051641;localization#GO:0051179;membrane assembly#GO:0071709;cellular component organization#GO:0016043;late endosome to vacuole transport#GO:0045324 cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;nuclear envelope#GO:0005635;membrane#GO:0016020;vesicle membrane#GO:0012506;nucleus#GO:0005634;cell periphery#GO:0071944;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic side of plasma membrane#GO:0009898;organelle envelope#GO:0031967;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115312512|UniProtKB=A0ACM8F4Q1 A0ACM8F4Q1 LOC115312512 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115332280|UniProtKB=A0ACM8F6F8 A0ACM8F6F8 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC120840934|UniProtKB=A0ACM8EQG0 A0ACM8EQG0 LOC120840934 PTHR47507:SF6 BARRIER TO AUTOINTEGRATION FACTOR 2 BARRIER-TO-AUTOINTEGRATION FACTOR DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840 chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;condensed chromosome#GO:0000793;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120846862|UniProtKB=A0ACM8F3D5 A0ACM8F3D5 SCCRO PTHR12281:SF32 RP42 RELATED DCN1-LIKE PROTEIN 1 acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;protein binding#GO:0005515;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of protein modification process#GO:0031399;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;positive regulation of protein metabolic process#GO:0051247;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;positive regulation of macromolecule metabolic process#GO:0010604;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of metabolic process#GO:0019222;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8023139|UniProtKB=A0ACM8E8K6 A0ACM8E8K6 Sce PTHR46076:SF3 E3 UBIQUITIN-PROTEIN LIGASE RING1 / RING 2 FAMILY MEMBER E3 UBIQUITIN-PROTEIN LIGASE RING1 catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;chromatin binding#GO:0003682;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;PcG protein complex#GO:0031519 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121836736|UniProtKB=A0ACM8G155 A0ACM8G155 LOC121836736 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8027561|UniProtKB=A0ACM8EH66 A0ACM8EH66 mRpL13 PTHR11545:SF45 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13M structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 negative regulation of translation#GO:0017148;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of protein metabolic process#GO:0051248;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8032733|UniProtKB=A0ACM8FDQ3 A0ACM8FDQ3 LOC8032733 PTHR24331:SF0 DBX DBX regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 IXOSC|EnsemblGenome=LOC8024979|UniProtKB=A0ACM8E3C1 A0ACM8E3C1 LOC8024979 PTHR28598:SF1 STAGA COMPLEX 65 SUBUNIT GAMMA STAGA COMPLEX 65 SUBUNIT GAMMA transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 IXOSC|EnsemblGenome=LOC8031144|UniProtKB=A0ACM8EFN0 A0ACM8EFN0 LOC8031144 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836694|UniProtKB=A0ACM8FZ70 A0ACM8FZ70 LOC121836694 PTHR12358:SF111 SPHINGOSINE KINASE CERAMIDE KINASE, ISOFORM A lipid kinase activity#GO:0001727;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 IXOSC|EnsemblGenome=LOC120849864|UniProtKB=A0ACM8F8H9 A0ACM8F8H9 LOC120849864 PTHR12286:SF5 SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247 intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8038196|UniProtKB=A0ACM8DGQ0 A0ACM8DGQ0 Tsen2 PTHR21227:SF0 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 TRNA-SPLICING ENDONUCLEASE SUBUNIT SEN2 catalytic activity, acting on a tRNA#GO:0140101;nuclease activity#GO:0004518;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA splicing, via endonucleolytic cleavage and ligation#GO:0006388;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;RNA splicing#GO:0008380;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555 endodeoxyribonuclease#PC00093;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8053777|UniProtKB=A0ACM8DLQ6 A0ACM8DLQ6 LOC8053777 PTHR11132:SF250 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E3 organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8030931|UniProtKB=A0ACM8DT93 A0ACM8DT93 LOC8030931 PTHR21780:SF0 TRANSMEMBRANE PROTEIN 209 TRANSMEMBRANE PROTEIN 209 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8031039|UniProtKB=A0ACM8FG02 A0ACM8FG02 LOC8031039 PTHR47219:SF32 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE TBC1 DOMAIN FAMILY MEMBER 12 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC115325961|UniProtKB=A0ACM8E6A7 A0ACM8E6A7 LOC115325961 PTHR46066:SF2 CHITINASE DOMAIN-CONTAINING PROTEIN 1 FAMILY MEMBER CHITINASE DOMAIN-CONTAINING PROTEIN 1 oligosaccharide binding#GO:0070492;binding#GO:0005488;carbohydrate binding#GO:0030246 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8039807|UniProtKB=A0ACM8DWW4 A0ACM8DWW4 LOC8039807 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115326152|UniProtKB=A0ACM8E6Y0 A0ACM8E6Y0 CRIF PTHR31761:SF1 GROWTH ARREST AND DNA DAMAGE-INDUCIBLE PROTEINS-INTERACTING PROTEIN 1 GADD45GIP1 LARGE RIBOSOMAL SUBUNIT PROTEIN ML64 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8050678|UniProtKB=A0ACM8FD86 A0ACM8FD86 LOC8050678 PTHR11566:SF212 DYNAMIN DYNAMIN ribonucleoside triphosphate phosphatase activity#GO:0017111;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;tubulin binding#GO:0015631;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;protein binding#GO:0005515;microtubule binding#GO:0008017;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;microtubule cytoskeleton#GO:0015630 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121837811|UniProtKB=A0ACM8G580 A0ACM8G580 LOC121837811 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115308169|UniProtKB=A0ACM8FJA5 A0ACM8FJA5 Mrm2 PTHR10920:SF18 RIBOSOMAL RNA METHYLTRANSFERASE RRNA METHYLTRANSFERASE 2, MITOCHONDRIAL catalytic activity, acting on a rRNA#GO:0140102;O-methyltransferase activity#GO:0008171;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;rRNA methyltransferase activity#GO:0008649;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640 ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;ribosome assembly#GO:0042255;RNA modification#GO:0009451;macromolecule methylation#GO:0043414;nucleic acid biosynthetic process#GO:0141187;methylation#GO:0032259;RNA metabolic process#GO:0016070;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;rRNA modification#GO:0000154;ribonucleoprotein complex biogenesis#GO:0022613;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;rRNA methylation#GO:0031167;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;RNA processing#GO:0006396;organelle assembly#GO:0070925;protein-RNA complex assembly#GO:0022618;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC120842242|UniProtKB=A0ACM8EUF3 A0ACM8EUF3 LOC120842242 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 IXOSC|EnsemblGenome=LOC8036680|UniProtKB=A0ACM8FUQ2 A0ACM8FUQ2 LOC8036680 PTHR11633:SF1 PLATELET-DERIVED GROWTH FACTOR LD28763P growth factor receptor binding#GO:0070851;binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 positive regulation of cell motility#GO:2000147;positive regulation of cell population proliferation#GO:0008284;regulation of biological process#GO:0050789;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cell migration#GO:0030335;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;regulation of cell migration#GO:0030334;regulation of cell population proliferation#GO:0042127;regulation of cell motility#GO:2000145;positive regulation of locomotion#GO:0040017 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 growth factor#PC00112 IXOSC|EnsemblGenome=LOC8024351|UniProtKB=A0ACM8EK81 A0ACM8EK81 Neurl4 PTHR12429:SF14 NEURALIZED NEURALIZED-LIKE PROTEIN 4 acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Notch signaling pathway#P00045>Neuralized#P01117 IXOSC|EnsemblGenome=LOC115319105|UniProtKB=A0ACM8FU03 A0ACM8FU03 LOC115319105 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120849682|UniProtKB=A0ACM8F898 A0ACM8F898 LOC120849682 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029846|UniProtKB=A0ACM8DMV4 A0ACM8DMV4 LOC8029846 PTHR23090:SF9 NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE ligase activity, forming carbon-nitrogen bonds#GO:0016879;ligase activity#GO:0016874;catalytic activity#GO:0003824 nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;oxoacid metabolic process#GO:0043436;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;indole-containing compound metabolic process#GO:0042430;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;nicotinamide nucleotide metabolic process#GO:0046496;NAD+ metabolic process#GO:0019674;organophosphate metabolic process#GO:0019637 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ligase#PC00142 IXOSC|EnsemblGenome=LOC8053276|UniProtKB=A0ACM8FWR9 A0ACM8FWR9 LOC8053276 PTHR14234:SF19 RIM BINDING PROTEIN-RELATED RIM-BINDING PROTEIN, ISOFORM F scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115326943|UniProtKB=A0ACM8E7Y4 A0ACM8E7Y4 LOC115326943 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8051454|UniProtKB=A0ACM8DQ18 A0ACM8DQ18 LOC8051454 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE-LIKE transferase#PC00220 IXOSC|EnsemblGenome=LOC8041250|UniProtKB=A0ACM8G3J9 A0ACM8G3J9 LOC8041250 PTHR11849:SF191 ETS ECDYSONE-INDUCED PROTEIN 74EF ISOFORM B transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 IXOSC|EnsemblGenome=LOC115313438|UniProtKB=A0ACM8EH96 A0ACM8EH96 LOC115313438 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115329218|UniProtKB=A0ACM8FT50 A0ACM8FT50 LOC115329218 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026342|UniProtKB=A0ACM8DHN1 A0ACM8DHN1 LOC8026342 PTHR14735:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 COILED-COIL DOMAIN-CONTAINING PROTEIN 134 molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115309406|UniProtKB=A0ACM8FAX6 A0ACM8FAX6 LOC115309406 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8044110|UniProtKB=A0ACM8DL80 A0ACM8DL80 LOC8044110 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115314533|UniProtKB=A0ACM8DTY1 A0ACM8DTY1 LOC115314533 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC121045775|UniProtKB=A0ACM8FLA9 A0ACM8FLA9 LOC121045775 PTHR24377:SF1039 IP01015P-RELATED SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8043778|UniProtKB=A0ACM8EG06 A0ACM8EG06 LOC8043778 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8030307|UniProtKB=A0ACM8DRP9 A0ACM8DRP9 LOC8030307 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115325588|UniProtKB=A0ACM8FCR6 A0ACM8FCR6 LOC115325588 PTHR11814:SF272 SULFATE TRANSPORTER SOLUTE CARRIER FAMILY 26 MEMBER 10P-RELATED monoatomic anion transmembrane transporter activity#GO:0008509;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;bicarbonate transmembrane transporter activity#GO:0015106;chloride transmembrane transporter activity#GO:0015108;dicarboxylic acid transmembrane transporter activity#GO:0005310;monoatomic ion transmembrane transporter activity#GO:0015075;carboxylic acid transmembrane transporter activity#GO:0046943 monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;localization#GO:0051179;chloride transmembrane transport#GO:1902476;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transport#GO:0006821;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8037708|UniProtKB=A0ACM8FEE9 A0ACM8FEE9 LOC8037708 PTHR10306:SF17 SYNAPTOPHYSIN MARVEL DOMAIN-CONTAINING PROTEIN intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;transport vesicle#GO:0030133;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;cytoplasm#GO:0005737 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC120843275|UniProtKB=A0ACM8EVT2 A0ACM8EVT2 LOC120843275 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8026793|UniProtKB=A0ACM8E4Q6 A0ACM8E4Q6 LOC8026793 PTHR11587:SF11 ARGININOSUCCINATE SYNTHASE ARGININOSUCCINATE SYNTHASE catalytic activity#GO:0003824;ligase activity#GO:0016874;ligase activity, forming carbon-nitrogen bonds#GO:0016879 proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;arginine metabolic process#GO:0006525;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid biosynthetic process#GO:0170038;L-arginine biosynthetic process#GO:0006526;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;ligase#PC00142 Arginine biosynthesis#P02728>Argininosuccinate synthase#P02840 IXOSC|EnsemblGenome=LOC115308428|UniProtKB=A0ACM8DMG3 A0ACM8DMG3 LOC115308428 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115323491|UniProtKB=A0ACM8EFI3 A0ACM8EFI3 LOC115323491 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC121046511|UniProtKB=A0ACM8FE84 A0ACM8FE84 LOC121046511 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331433|UniProtKB=A0ACM8EGT5 A0ACM8EGT5 LOC115331433 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040900|UniProtKB=A0ACM8FST4 A0ACM8FST4 LOC8040900 PTHR22950:SF244 AMINO ACID TRANSPORTER NEUTRAL AMINO ACID TRANSPORTER 9 carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 transport#GO:0006810;amino acid transport#GO:0006865;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;lysosomal membrane#GO:0005765;vacuolar membrane#GO:0005774;lytic vacuole#GO:0000323;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;lytic vacuole membrane#GO:0098852;lysosome#GO:0005764;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 secondary carrier transporter#PC00258;amino acid transporter#PC00046 IXOSC|EnsemblGenome=LOC120842245|UniProtKB=A0ACM8ETC1 A0ACM8ETC1 LOC120842245 PTHR23055:SF69 CALCIUM BINDING PROTEINS NEURONAL CALCIUM SENSOR 2 metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC115319212|UniProtKB=A0ACM8ETH7 A0ACM8ETH7 LOC115319212 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to chemical#GO:0042221;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115323296|UniProtKB=A0ACM8FVJ1 A0ACM8FVJ1 LOC115323296 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120843104|UniProtKB=A0ACM8EV85 A0ACM8EV85 LOC120843104 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121835454|UniProtKB=A0ACM8FU22 A0ACM8FU22 LOC121835454 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120841325|UniProtKB=A0ACM8ERF2 A0ACM8ERF2 LOC120841325 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842362|UniProtKB=A0ACM8EUQ1 A0ACM8EUQ1 PTHR37162:SF10 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323521|UniProtKB=A0ACM8FBN4 A0ACM8FBN4 LOC115323521 PTHR10900:SF126 PERIOSTIN-RELATED MUCIN-5AC-RELATED protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120848766|UniProtKB=A0ACM8F5J5 A0ACM8F5J5 LOC120848766 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8039817|UniProtKB=A0ACM8EC51 A0ACM8EC51 LOC8039817 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115311418|UniProtKB=A0ACM8DQY8 A0ACM8DQY8 Coq9 PTHR21427:SF19 UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL UBIQUINONE BIOSYNTHESIS PROTEIN COQ9, MITOCHONDRIAL binding#GO:0005488;lipid binding#GO:0008289 metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;ketone metabolic process#GO:0042180;ubiquinone biosynthetic process#GO:0006744;ketone biosynthetic process#GO:0042181;cellular process#GO:0009987 mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120844779|UniProtKB=A0ACM8EZS3 A0ACM8EZS3 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024115|UniProtKB=A0ACM8ECC5 A0ACM8ECC5 LOC8024115 PTHR13958:SF3 CENTROSOME-ASSOCIATED PROTEIN 350 CAP-GLY DOMAIN-CONTAINING PROTEIN-RELATED non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC120838375|UniProtKB=A0ACM8FK92 A0ACM8FK92 LOC120838375 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8052874|UniProtKB=A0ACM8FZQ6 A0ACM8FZQ6 LOC8052874 PTHR47537:SF6 CUBILIN CUB DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC115317099|UniProtKB=A0ACM8EK39 A0ACM8EK39 LOC115317099 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115312625|UniProtKB=A0ACM8FRY2 A0ACM8FRY2 LOC115312625 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120841564|UniProtKB=A0ACM8ES07 A0ACM8ES07 PTHR33064:SF47 POL PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843835|UniProtKB=A0ACM8EX20 A0ACM8EX20 LOC120843835 PTHR33964:SF10 RE45066P-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115311322|UniProtKB=A0ACM8DQL9 A0ACM8DQL9 LOC115311322 PTHR46331:SF2 VALACYCLOVIR HYDROLASE SERINE HYDROLASE BPHL hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121838151|UniProtKB=A0ACM8G6Z6 A0ACM8G6Z6 LOC121838151 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC121835203|UniProtKB=A0ACM8FSQ4 A0ACM8FSQ4 LOC121835203 PTHR24350:SF34 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;regulation of cell cycle#GO:0051726;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794;mitotic spindle organization#GO:0007052;regulation of cell division#GO:0051302;regulation of cytokinesis#GO:0032465;microtubule cytoskeleton organization#GO:0000226;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 kinetochore#GO:0000776;spindle pole#GO:0000922;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;chromosomal region#GO:0098687;spindle midzone#GO:0051233;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;spindle microtubule#GO:0005876;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;centrosome#GO:0005813;spindle#GO:0005819;microtubule organizing center#GO:0005815;condensed chromosome#GO:0000793;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8043761|UniProtKB=A0ACM8ELE2 A0ACM8ELE2 LOC8043761 PTHR16768:SF5 DOWN REGULATED IN RENAL CARCINOMA 1/TU3A FI14214P IXOSC|EnsemblGenome=LOC8043278|UniProtKB=A0ACM8DL43 A0ACM8DL43 LOC8043278 PTHR10293:SF16 GLUTAREDOXIN FAMILY MEMBER GLUTAREDOXIN-RELATED PROTEIN 5, MITOCHONDRIAL disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120850618|UniProtKB=A0ACM8F971 A0ACM8F971 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121834098|UniProtKB=A0ACM8FMU6 A0ACM8FMU6 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8036920|UniProtKB=A0ACM8DP71 A0ACM8DP71 Mitf PTHR45776:SF2 MIP04163P MIP04163P sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8035302|UniProtKB=A0ACM8DW87 A0ACM8DW87 Ada2b PTHR12374:SF63 TRANSCRIPTIONAL ADAPTOR 2 ADA2 -RELATED TRANSCRIPTIONAL ADAPTER 2-BETA transcription coactivator activity#GO:0003713;binding#GO:0005488;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;SAGA-type complex#GO:0070461;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8035246|UniProtKB=A0ACM8EAL2 A0ACM8EAL2 LOC8035246 PTHR24322:SF755 PKSB RETINOL DEHYDROGENASE 10 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 intracellular anatomical structure#GO:0005622;intracellular membraneless organelle#GO:0043232;lipid droplet#GO:0005811;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120837166|UniProtKB=A0ACM8EGT3 A0ACM8EGT3 LOC120837166 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047830|UniProtKB=A0ACM8FGZ2 A0ACM8FGZ2 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120851153|UniProtKB=A0ACM8FBJ6 A0ACM8FBJ6 PTHR46814:SF1 EGALITARIAN, ISOFORM B EGALITARIAN, ISOFORM B RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA localization#GO:0006403;localization#GO:0051179;macromolecule localization#GO:0033036 IXOSC|EnsemblGenome=LOC8023593|UniProtKB=A0ACM8DHC1 A0ACM8DHC1 Cpsf73 PTHR11203:SF11 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;RNA binding#GO:0003723 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;mRNA cleavage factor complex#GO:0005849;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8030101|UniProtKB=A0ACM8F7B5 A0ACM8F7B5 LOC8030101 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121833124|UniProtKB=A0ACM8FJL5 A0ACM8FJL5 LOC121833124 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC115328812|UniProtKB=A0ACM8G423 A0ACM8G423 LOC115328812 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8037710|UniProtKB=A0ACM8EEI3 A0ACM8EEI3 LOC8037710 PTHR22748:SF4 AP ENDONUCLEASE DNA-(APURINIC OR APYRIMIDINIC SITE) ENDONUCLEASE 2 hydrolase activity#GO:0016787;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA endonuclease activity#GO:0004520;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;exonuclease activity#GO:0004527;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;DNA exonuclease activity#GO:0004529 macromolecule metabolic process#GO:0043170;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8026654|UniProtKB=A0ACM8DI47 A0ACM8DI47 LOC8026654 PTHR28637:SF1 DNA REPLICATION FACTOR CDT1 DNA REPLICATION FACTOR CDT1 binding#GO:0005488;nucleic acid binding#GO:0003676;enzyme binding#GO:0019899;protein binding#GO:0005515;DNA binding#GO:0003677 negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;DNA replication checkpoint signaling#GO:0000076;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;DNA integrity checkpoint signaling#GO:0031570;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of DNA-templated DNA replication initiation#GO:0030174;cell cycle checkpoint signaling#GO:0000075;regulation of nucleobase-containing compound metabolic process#GO:0019219;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of DNA replication#GO:0006275;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;cellular response to stimulus#GO:0051716;regulation of DNA-templated DNA replication#GO:0090329;negative regulation of biological process#GO:0048519;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of cell cycle phase transition#GO:1901988;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of macromolecule metabolic process#GO:0060255;mitotic cell cycle#GO:0000278;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115323754|UniProtKB=A0ACM8F0V2 A0ACM8F0V2 LOC115323754 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8036504|UniProtKB=A0ACM8DJZ9 A0ACM8DJZ9 LOC8036504 PTHR22809:SF5 METHYLTRANSFERASE-RELATED TRNA N(3)-CYTIDINE METHYLTRANSFERASE METTL6 methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8051843|UniProtKB=A0ACM8FFF3 A0ACM8FFF3 LOC8051843 PTHR31395:SF26 SHISA GEO05642P1-RELATED scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115312062|UniProtKB=A0ACM8EFT6 A0ACM8EFT6 LOC115312062 PTHR21220:SF0 DNA-DEPENDENT METALLOPROTEASE SPRTN DNA-DEPENDENT METALLOPROTEASE SPRTN endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 DNA synthesis involved in DNA replication#GO:0090592;cellular response to stress#GO:0033554;nucleic acid biosynthetic process#GO:0141187;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;translesion synthesis#GO:0019985;DNA biosynthetic process#GO:0071897;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to stress#GO:0006950 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120840042|UniProtKB=A0ACM8EN46 A0ACM8EN46 LOC120840042 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;cellular process#GO:0009987;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8024167|UniProtKB=A0ACM8EAD0 A0ACM8EAD0 LOC8024167 PTHR12299:SF17 HYALURONIC ACID-BINDING PROTEIN 4 AT19571P-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8042115|UniProtKB=A0ACM8ENG8 A0ACM8ENG8 LOC8042115 PTHR45819:SF5 CENTAURIN-GAMMA-1A CENTAURIN-GAMMA-1A molecular function activator activity#GO:0140677;hydrolase activity#GO:0016787;enzyme regulator activity#GO:0030234;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;hydrolase activity, acting on acid anhydrides#GO:0016817;enzyme activator activity#GO:0008047;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC8032303|UniProtKB=A0ACM8E5A5 A0ACM8E5A5 LOC8032303 PTHR14625:SF3 MICROCEPHALIN MICROCEPHALIN cell cycle#GO:0007049;cellular process#GO:0009987;mitotic cell cycle#GO:0000278 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8053160|UniProtKB=A0ACM8DM14 A0ACM8DM14 LOC8053160 PTHR14386:SF2 PROTEIN FAM204A PROTEIN FAM204A IXOSC|EnsemblGenome=LOC115314706|UniProtKB=A0ACM8EY31 A0ACM8EY31 LOC115314706 PTHR45625:SF1 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED RING-TYPE E3 UBIQUITIN-PROTEIN LIGASE PPIL2 cis-trans isomerase activity#GO:0016859;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;catalytic activity#GO:0003824;transferase activity#GO:0016740 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8032238|UniProtKB=A0ACM8EUG9 A0ACM8EUG9 LOC8032238 PTHR43767:SF1 LONG-CHAIN-FATTY-ACID--COA LIGASE NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC115322726|UniProtKB=A0ACM8G1K4 A0ACM8G1K4 LOC115322726 PTHR43333:SF1 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC8034408|UniProtKB=A0ACM8FSL4 A0ACM8FSL4 LOC8034408 PTHR14319:SF3 FIVE-SPAN TRANSMEMBRANE PROTEIN M83 TRANSMEMBRANE PROTEIN-LIKE PROTEIN cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8034848|UniProtKB=A0ACM8FB85 A0ACM8FB85 LOC8034848 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311212|UniProtKB=A0ACM8FAU2 A0ACM8FAU2 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 localization#GO:0051179;organelle localization#GO:0051640;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;nucleus organization#GO:0006997;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;membrane organization#GO:0061024;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;protein localization to nucleus#GO:0034504;epigenetic regulation of gene expression#GO:0040029;macromolecule localization#GO:0033036;negative regulation of macromolecule metabolic process#GO:0010605;cellular localization#GO:0051641;establishment of organelle localization#GO:0051656;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC8025110|UniProtKB=A0ACM8DUT3 A0ACM8DUT3 LOC8025110 PTHR11468:SF13 GLYCOGEN PHOSPHORYLASE GLYCOGEN PHOSPHORYLASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 carbohydrate catabolic process#GO:0016052;energy reserve metabolic process#GO:0006112;catabolic process#GO:0009056;polysaccharide metabolic process#GO:0005976;carbohydrate metabolic process#GO:0005975;glucan catabolic process#GO:0009251;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;glucan metabolic process#GO:0044042;polysaccharide catabolic process#GO:0000272;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;generation of precursor metabolites and energy#GO:0006091;glycogen catabolic process#GO:0005980;cellular process#GO:0009987 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120842829|UniProtKB=A0ACM8EUJ3 A0ACM8EUJ3 LOC120842829 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;circulatory system development#GO:0072359;heart development#GO:0007507;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 IXOSC|EnsemblGenome=LOC8031597|UniProtKB=A0ACM8ENS7 A0ACM8ENS7 LOC8031597 PTHR11686:SF9 GAMMA GLUTAMYL TRANSPEPTIDASE GAMMA-GLUTAMYL TRANSPEPTIDASE, ISOFORM A catalytic activity#GO:0003824;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 catabolic process#GO:0009056;sulfur compound catabolic process#GO:0044273;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC120850177|UniProtKB=A0ACM8FAB7 A0ACM8FAB7 LOC120850177 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120841744|UniProtKB=A0ACM8ETE2 A0ACM8ETE2 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8051846|UniProtKB=A0ACM8DLZ0 A0ACM8DLZ0 l(2)k10201 PTHR21354:SF0 ZINC FINGER PROTEIN 511 ZINC FINGER PROTEIN 511 IXOSC|EnsemblGenome=LOC120841052|UniProtKB=A0ACM8FVL5 A0ACM8FVL5 LOC120841052 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115328094|UniProtKB=A0ACM8EJ75 A0ACM8EJ75 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121048451|UniProtKB=A0ACM8FIG3 A0ACM8FIG3 LOC121048451 PTHR19303:SF82 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053705|UniProtKB=A0ACM8DQW2 A0ACM8DQW2 LOC8053705 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC8024768|UniProtKB=A0ACM8EA99 A0ACM8EA99 Mlc-c PTHR23048:SF0 MYOSIN LIGHT CHAIN 1, 3 FI08416P-RELATED intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;myosin complex#GO:0016459;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC120840761|UniProtKB=A0ACM8EPN0 A0ACM8EPN0 LOC120840761 PTHR12830:SF9 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 ANAPHASE-PROMOTING COMPLEX SUBUNIT 5 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of chromosome segregation#GO:0051983;positive regulation of mitotic nuclear division#GO:0045840;regulation of chromosome separation#GO:1905818;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;positive regulation of cell cycle#GO:0045787;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mitotic cell cycle phase transition#GO:1901990;positive regulation of organelle organization#GO:0010638;protein modification by small protein conjugation or removal#GO:0070647;anaphase-promoting complex-dependent catabolic process#GO:0031145;positive regulation of cellular component organization#GO:0051130;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;protein K11-linked ubiquitination#GO:0070979;positive regulation of cell cycle process#GO:0090068;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;regulation of organelle organization#GO:0033043;macromolecule metabolic process#GO:0043170;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of mitotic cell cycle#GO:0045931;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;regulation of chromosome organization#GO:0033044;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nuclear division#GO:0051783;positive regulation of cellular process#GO:0048522;regulation of mitotic cell cycle#GO:0007346;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;catabolic process#GO:0009056;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cellular process#GO:0050794;regulation of cell cycle phase transition#GO:1901987;primary metabolic process#GO:0044238;protein modification process#GO:0036211;modification-dependent protein catabolic process#GO:0019941 intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152 IXOSC|EnsemblGenome=LOC121838147|UniProtKB=A0ACM8G6K8 A0ACM8G6K8 LOC121838147 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8026740|UniProtKB=A0ACM8DMS3 A0ACM8DMS3 Rpn5 PTHR10855:SF1 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12/COP9 SIGNALOSOME COMPLEX SUBUNIT 4 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 12 proteasome complex#GO:0000502;cytoplasm#GO:0005737;peptidase complex#GO:1905368;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;endopeptidase complex#GO:1905369;proteasome regulatory particle, lid subcomplex#GO:0008541;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 protease#PC00190 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 IXOSC|EnsemblGenome=LOC121835654|UniProtKB=A0ACM8FUJ8 A0ACM8FUJ8 LOC121835654 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120849124|UniProtKB=A0ACM8F831 A0ACM8F831 LOC120849124 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8039243|UniProtKB=A0ACM8G237 A0ACM8G237 LOC8039243 PTHR14233:SF4 DUF914-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F2 IXOSC|EnsemblGenome=LOC120850684|UniProtKB=A0ACM8G777 A0ACM8G777 LOC120850684 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8028851|UniProtKB=A0ACM8DWA6 A0ACM8DWA6 LOC8028851 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032750|UniProtKB=A0ACM8EBW6 A0ACM8EBW6 LOC8032750 PTHR19384:SF17 NITRIC OXIDE SYNTHASE-RELATED NADPH--CYTOCHROME P450 REDUCTASE oxidoreductase activity, acting on NAD(P)H#GO:0016651;binding#GO:0005488;small molecule binding#GO:0036094;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;catalytic activity#GO:0003824;carbohydrate derivative binding#GO:0097367 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Vitamin D metabolism and pathway#P04396>P450 reductase#P04605 IXOSC|EnsemblGenome=LOC115308567|UniProtKB=A0ACM8DMN2 A0ACM8DMN2 LOC115308567 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034612|UniProtKB=A0ACM8E0B4 A0ACM8E0B4 LOC8034612 PTHR10985:SF77 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED PROTEIN HAIRY DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 pattern specification process#GO:0007389;regulation of nervous system development#GO:0051960;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of neurogenesis#GO:0050767;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;multicellular organism development#GO:0007275;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of multicellular organismal process#GO:0051239 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 IXOSC|EnsemblGenome=LOC8032094|UniProtKB=A0ACM8G6F1 A0ACM8G6F1 LOC8032094 PTHR11011:SF129 MALE STERILITY PROTEIN 2-RELATED FATTY ACYL-COA REDUCTASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620 acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793 organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8029448|UniProtKB=A0ACM8EA65 A0ACM8EA65 LOC8029448 PTHR22914:SF42 CHITIN SYNTHASE CHITIN SYNTHASE acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;chitin metabolic process#GO:0006030;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;aminoglycan biosynthetic process#GO:0006023;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;biosynthetic process#GO:0009058 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transferase#PC00220 IXOSC|EnsemblGenome=LOC8041128|UniProtKB=A0ACM8F3D1 A0ACM8F3D1 LOC8041128 PTHR11654:SF678 OLIGOPEPTIDE TRANSPORTER-RELATED PEPTIDE TRANSPORTER FAMILY 1 dipeptide transmembrane transporter activity#GO:0071916;oligopeptide transmembrane transporter activity#GO:0035673;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 oligopeptide transmembrane transport#GO:0035672;cellular process#GO:0009987;peptide transport#GO:0015833;nitrogen compound transport#GO:0071705;import across plasma membrane#GO:0098739;transport#GO:0006810;oligopeptide transport#GO:0006857;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;import into cell#GO:0098657;dipeptide transport#GO:0042938 apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115316746|UniProtKB=A0ACM8DWA5 A0ACM8DWA5 LOC115316746 PTHR48522:SF1 MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN MUTATOR-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837319|UniProtKB=A0ACM8G2T7 A0ACM8G2T7 LOC121837319 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8044030|UniProtKB=A0ACM8DL71 A0ACM8DL71 Lipt2 PTHR10993:SF7 OCTANOYLTRANSFERASE OCTANOYL-[ACYL-CARRIER-PROTEIN]:PROTEIN N-OCTANOYLTRANSFERASE LIPT2, MITOCHONDRIAL acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 transferase#PC00220 Lipoate_biosynthesis#P02750>Lipoyl-protein ligase#P03003 IXOSC|EnsemblGenome=LOC120849567|UniProtKB=A0ACM8E3V4 A0ACM8E3V4 LOC8026610 PTHR11384:SF59 ATP-BINDING CASSETTE, SUB-FAMILY D MEMBER LYSOSOMAL COBALAMIN TRANSPORTER ABCD4 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657 ATP-binding cassette (ABC) transporter#PC00003;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8029193|UniProtKB=A0ACM8E3N0 A0ACM8E3N0 rictor PTHR13298:SF11 CYTOSOLIC REGULATOR PIANISSIMO RAPAMYCIN-INSENSITIVE COMPANION OF MTOR structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 regulation of response to stimulus#GO:0048583;positive regulation of intracellular signal transduction#GO:1902533;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;TOR signaling#GO:0031929;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;intracellular signal transduction#GO:0035556;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;TORC2 signaling#GO:0038203;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;response to stimulus#GO:0050896;positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051897 protein-containing complex#GO:0032991;TOR complex#GO:0038201;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC115325762|UniProtKB=A0ACM8F119 A0ACM8F119 LOC115325762 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8027942|UniProtKB=A0ACM8DJI3 A0ACM8DJI3 LOC8027942 PTHR11075:SF54 PEPTIDE CHAIN RELEASE FACTOR LARGE RIBOSOMAL SUBUNIT PROTEIN ML62 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;translation factor activity#GO:0180051;catalytic activity, acting on RNA#GO:0140098;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;catalytic activity, acting on a tRNA#GO:0140101 translation release factor#PC00225 IXOSC|EnsemblGenome=LOC121047591|UniProtKB=A0ACM8G1W2 A0ACM8G1W2 LOC121047591 PTHR11920:SF335 GUANYLYL CYCLASE GUANYLATE CYCLASE cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849;catalytic activity#GO:0003824;signaling receptor activity#GO:0038023;guanylate cyclase activity#GO:0004383;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;lyase activity#GO:0016829 cyclic nucleotide metabolic process#GO:0009187;nucleoside phosphate biosynthetic process#GO:1901293;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cGMP metabolic process#GO:0046068;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cell communication#GO:0007154;cGMP biosynthetic process#GO:0006182;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;cyclic purine nucleotide metabolic process#GO:0052652;cell surface receptor signaling pathway#GO:0007166;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;ribose phosphate biosynthetic process#GO:0046390;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;ribonucleotide metabolic process#GO:0009259;cyclic nucleotide biosynthetic process#GO:0009190;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide biosynthetic process#GO:0009165;phosphorus metabolic process#GO:0006793;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 lyase#PC00144;guanylate cyclase#PC00114 IXOSC|EnsemblGenome=LOC121047564|UniProtKB=A0ACM8FG75 A0ACM8FG75 LOC121047564 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034134|UniProtKB=A0ACM8E422 A0ACM8E422 LOC8034134 PTHR31017:SF1 LATE SECRETORY PATHWAY PROTEIN AVL9-RELATED LATE SECRETORY PATHWAY PROTEIN AVL9 HOMOLOG cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8052203|UniProtKB=A0ACM8DWT4 A0ACM8DWT4 LOC8052203 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027441|UniProtKB=A0ACM8EEI7 A0ACM8EEI7 LOC8027441 PTHR14186:SF27 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-RELATED INSULIN-LIKE GROWTH FACTOR-BINDING PROTEIN 7 signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121837457|UniProtKB=A0ACM8G392 A0ACM8G392 LOC121837457 PTHR13817:SF166 TITIN MYOMESIN AND MYOSIN BINDING PROTEIN structural protein#PC00211 IXOSC|EnsemblGenome=LOC120841800|UniProtKB=A0ACM8FZQ5 A0ACM8FZQ5 LOC120841800 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120844903|UniProtKB=A0ACM8EZH9 A0ACM8EZH9 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8037736|UniProtKB=A0ACM8DMF7 A0ACM8DMF7 LOC8037736 PTHR24329:SF585 HOMEOBOX PROTEIN ARISTALESS FI01017P-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;neuron development#GO:0048666;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;cell development#GO:0048468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8036468|UniProtKB=A0ACM8DK08 A0ACM8DK08 LOC8036468 PTHR12224:SF0 BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;glycosyltransferase activity#GO:0016757 amino sugar metabolic process#GO:0006040;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115329684|UniProtKB=A0ACM8EBE5 A0ACM8EBE5 LOC115329684 PTHR44229:SF4 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] CHAIN DEHYDROGENASE_REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02990)-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8052809|UniProtKB=A0ACM8EN93 A0ACM8EN93 LOC8052809 PTHR31389:SF4 LD39211P LD39211P IXOSC|EnsemblGenome=LOC120843936|UniProtKB=A0ACM8EX84 A0ACM8EX84 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter#PC00227 IXOSC|EnsemblGenome=LOC121832873|UniProtKB=A0ACM8FRZ4 A0ACM8FRZ4 LOC121832873 PTHR45712:SF36 AGAP008170-PA PODOCAN ISOFORM X1 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8053723|UniProtKB=A0ACM8ERN6 A0ACM8ERN6 Ptpa PTHR10012:SF0 SERINE/THREONINE-PROTEIN PHOSPHATASE 2A REGULATORY SUBUNIT B SERINE_THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR protein phosphatase regulator activity#GO:0019888;cis-trans isomerase activity#GO:0016859;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;isomerase activity#GO:0016853;phosphatase activator activity#GO:0019211;molecular function regulator activity#GO:0098772;phosphatase regulator activity#GO:0019208;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047 cytoskeleton organization#GO:0007010;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;cellular process#GO:0009987;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;organelle organization#GO:0006996;cell cycle#GO:0007049;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization#GO:0000226;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 phosphatase activator#PC00182 IXOSC|EnsemblGenome=LOC120840858|UniProtKB=A0ACM8EQ89 A0ACM8EQ89 LOC120840858 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC121046900|UniProtKB=A0ACM8FG39 A0ACM8FG39 LOC121046900 PTHR46609:SF6 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN EXONUCLEASE, PHAGE-TYPE_RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121045901|UniProtKB=A0ACM8FCD6 A0ACM8FCD6 LOC121045901 PTHR24356:SF450 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TRICORNERED protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;establishment or maintenance of cell polarity#GO:0007163;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8027084|UniProtKB=A0ACM8FRU3 A0ACM8FRU3 LOC8027084 PTHR15319:SF1 TATA BOX-BINDING PROTEIN ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C TATA BOX-BINDING PROTEIN-ASSOCIATED FACTOR RNA POLYMERASE I SUBUNIT C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046 nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 General transcription by RNA polymerase I#P00022>SL1 complex#P00653;Transcription regulation by bZIP transcription factor#P00055>TBP-associated factors#P01385;General transcription by RNA polymerase I#P00022>TAF-IC#P00649;General transcription regulation#P00023>TBP-associated factors#P00658 IXOSC|EnsemblGenome=LOC120836445|UniProtKB=A0ACM8EF36 A0ACM8EF36 LOC120836445 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029864|UniProtKB=A0ACM8EBJ3 A0ACM8EBJ3 LOC8029864 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121833854|UniProtKB=A0ACM8FPB8 A0ACM8FPB8 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853 nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;cell cycle process#GO:0022402;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA damage response#GO:0006974;DNA repair#GO:0006281;reproductive process#GO:0022414;homologous recombination#GO:0035825;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC115313409|UniProtKB=A0ACM8G791 A0ACM8G791 LOC115313409 PTHR10704:SF44 CARBOHYDRATE SULFOTRANSFERASE LD35051P-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;amino sugar metabolic process#GO:0006040 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8024821|UniProtKB=A0ACM8DWA4 A0ACM8DWA4 LOC8024821 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 oxidoreductase complex#GO:1990204;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121836638|UniProtKB=A0ACM8FZJ4 A0ACM8FZJ4 LOC121836638 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120847820|UniProtKB=A0ACM8F4X4 A0ACM8F4X4 LOC120847820 PTHR10751:SF144 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 heterotrimeric G-protein#PC00117;G-protein#PC00020 IXOSC|EnsemblGenome=LOC120839291|UniProtKB=A0ACM8ELU6 A0ACM8ELU6 LOC120839291 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC121835859|UniProtKB=A0ACM8FX95 A0ACM8FX95 LOC121835859 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8029361|UniProtKB=A0ACM8G912 A0ACM8G912 LOC8029361 PTHR48041:SF78 ABC TRANSPORTER G FAMILY MEMBER 28 ABC TRANSPORTER EXPRESSED IN TRACHEA, ISOFORM A primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATPase-coupled transmembrane transporter activity#GO:0042626 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;primary active transporter#PC00068;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8027966|UniProtKB=A0ACM8E7Q8 A0ACM8E7Q8 Swt1 PTHR16161:SF0 TRANSCRIPTIONAL PROTEIN SWT1 TRANSCRIPTIONAL PROTEIN SWT1 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540 regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;nuclear mRNA surveillance#GO:0071028;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115315538|UniProtKB=A0ACM8EKN4 A0ACM8EKN4 LOC115315538 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121836872|UniProtKB=A0ACM8G2D6 A0ACM8G2D6 LOC121836872 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115320194|UniProtKB=A0ACM8E032 A0ACM8E032 LOC115320194 PTHR12428:SF70 OXA1 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977;molecular carrier activity#GO:0140104 protein-containing complex assembly#GO:0065003;protein localization to mitochondrion#GO:0070585;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;respiratory chain complex IV assembly#GO:0008535;localization#GO:0051179;cellular localization#GO:0051641;mitochondrial membrane organization#GO:0007006;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;cytochrome complex assembly#GO:0017004;mitochondrial respiratory chain complex IV assembly#GO:0033617;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966 transporter#PC00227 IXOSC|EnsemblGenome=LOC8042400|UniProtKB=A0ACM8DSJ9 A0ACM8DSJ9 LOC8042400 PTHR23310:SF77 ACYL-COA-BINDING PROTEIN, ACBP LD25952P lipid binding#GO:0008289;heterocyclic compound binding#GO:1901363;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;small molecule metabolic process#GO:0044281 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115322778|UniProtKB=A0ACM8EWL2 A0ACM8EWL2 LOC115322778 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115328324|UniProtKB=A0ACM8FP83 A0ACM8FP83 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028850|UniProtKB=A0ACM8FMD2 A0ACM8FMD2 LOC8028850 PTHR46273:SF4 MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED AT19640P molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115315739|UniProtKB=A0ACM8DV56 A0ACM8DV56 LOC115315739 PTHR15577:SF2 ZINC FINGER CONTAINING PROTEIN ZINC FINGER PROTEIN 318 negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121047096|UniProtKB=A0ACM8G4R2 A0ACM8G4R2 LOC121047096 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115311080|UniProtKB=A0ACM8ET15 A0ACM8ET15 LOC115311080 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043083|UniProtKB=A0ACM8EPG6 A0ACM8EPG6 LOC8043083 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115309146|UniProtKB=A0ACM8F1F5 A0ACM8F1F5 LOC115309146 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120850220|UniProtKB=A0ACM8F9D2 A0ACM8F9D2 LOC120850220 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120840920|UniProtKB=A0ACM8EQE5 A0ACM8EQE5 LOC120840920 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8035392|UniProtKB=A0ACM8DJQ6 A0ACM8DJQ6 LOC8035392 PTHR14211:SF7 GLIOMA SUPPRESSOR CANDIDATE REGION GENE 2 RIBOSOME BIOGENESIS PROTEIN NOP53 RNA binding#GO:0003723;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;protein-containing complex assembly#GO:0065003;RNA metabolic process#GO:0016070;ribosome assembly#GO:0042255;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;protein-containing complex organization#GO:0043933;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein-RNA complex assembly#GO:0022618;rRNA processing#GO:0006364;organelle assembly#GO:0070925;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribosomal large subunit assembly#GO:0000027;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;rRNA metabolic process#GO:0016072 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 IXOSC|EnsemblGenome=LOC120843602|UniProtKB=A0ACM8EXL1 A0ACM8EXL1 LOC120843602 PTHR17985:SF28 SER/THR-RICH PROTEIN T10 IN DGCR REGION TRANSPORT AND GOLGI ORGANIZATION PROTEIN 2 HOMOLOG cellular component organization#GO:0016043;protein localization to extracellular region#GO:0071692;Golgi organization#GO:0007030;export from cell#GO:0140352;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;protein transport#GO:0015031;secretion by cell#GO:0032940;organelle organization#GO:0006996;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;endomembrane system organization#GO:0010256;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 IXOSC|EnsemblGenome=LOC8037187|UniProtKB=A0ACM8E478 A0ACM8E478 LOC8037187 PTHR10125:SF31 P2X PURINOCEPTOR P2X RECEPTOR E monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276 monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;calcium ion transport#GO:0006816;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC115316178|UniProtKB=A0ACM8DWA2 A0ACM8DWA2 LOC115316178 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836505|UniProtKB=A0ACM8FJ48 A0ACM8FJ48 LOC120836505 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8026095|UniProtKB=A0ACM8FTU0 A0ACM8FTU0 Pka-C1 PTHR24353:SF153 CYCLIC NUCLEOTIDE-DEPENDENT PROTEIN KINASE CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT 1 protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cell communication#GO:0007154;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 nucleus#GO:0005634;cytosol#GO:0005829;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>PKA#P01075;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PKA#P00862;Histamine H2 receptor mediated signaling pathway#P04386>PKA#P04491;Metabotropic glutamate receptor group I pathway#P00041>PKA#P01059;Dopamine receptor mediated signaling pathway#P05912>PKA#P05946;Metabotropic glutamate receptor group II pathway#P00040>PKA#P01050;Beta2 adrenergic receptor signaling pathway#P04378>PKA#P04444;Endothelin signaling pathway#P00019>PKA#P00570;5HT1 type receptor mediated signaling pathway#P04373>PKA#P04403;Metabotropic glutamate receptor group III pathway#P00039>PKA#P01035;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>PKA#P00746;Beta1 adrenergic receptor signaling pathway#P04377>PKA#P04437;Enkephalin release#P05913>PKA#P05972 IXOSC|EnsemblGenome=LOC8038209|UniProtKB=A0ACM8E6B2 A0ACM8E6B2 LOC8038209 PTHR13299:SF0 PEROXISOMAL MEMBRANE PROTEIN PEX16 PEROXISOMAL MEMBRANE PROTEIN PEX16 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;peroxisome organization#GO:0007031;cellular component organization or biogenesis#GO:0071840 peroxisome#GO:0005777;membrane#GO:0016020;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC120840586|UniProtKB=A0ACM8FDB6 A0ACM8FDB6 LOC120840586 PTHR46060:SF3 MARINER MOS1 TRANSPOSASE-LIKE PROTEIN PROTEIN GVQW3 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8050826|UniProtKB=A0ACM8EH05 A0ACM8EH05 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121048254|UniProtKB=A0ACM8FHS0 A0ACM8FHS0 LOC121048254 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121833050|UniProtKB=A0ACM8FJ11 A0ACM8FJ11 LOC121833050 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8029247|UniProtKB=A0ACM8FV88 A0ACM8FV88 LOC8029247 PTHR22907:SF54 GH04558P GH04558P IXOSC|EnsemblGenome=LOC115315026|UniProtKB=A0ACM8EHG2 A0ACM8EHG2 LOC115315026 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115320811|UniProtKB=A0ACM8FC31 A0ACM8FC31 LOC115320811 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115327679|UniProtKB=A0ACM8E8Q1 A0ACM8E8Q1 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8032994|UniProtKB=A0ACM8F5J2 A0ACM8F5J2 LOC8032994 PTHR46925:SF5 G-PROTEIN COUPLED RECEPTOR TKR-1-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;neuropeptide receptor activity#GO:0008188;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120836854|UniProtKB=A0ACM8FB51 A0ACM8FB51 LOC120836854 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121046013|UniProtKB=A0ACM8FCN7 A0ACM8FCN7 LOC121046013 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313762|UniProtKB=A0ACM8F5U3 A0ACM8F5U3 LOC115313762 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053105|UniProtKB=A0ACM8FRT0 A0ACM8FRT0 LOC8053105 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8035108|UniProtKB=A0ACM8E837 A0ACM8E837 LOC8035108 PTHR22846:SF2 WD40 REPEAT PROTEIN F-BOX-LIKE_WD REPEAT-CONTAINING PROTEIN EBI binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of cellular process#GO:0048523;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;transcription repressor complex#GO:0017053;protein-containing complex#GO:0032991;nucleus#GO:0005634;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974 Wnt signaling pathway#P00057>Ebi#P01453 IXOSC|EnsemblGenome=LOC120843126|UniProtKB=A0ACM8FLD4 A0ACM8FLD4 LOC120843126 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115308773|UniProtKB=A0ACM8DMY7 A0ACM8DMY7 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120846351|UniProtKB=A0ACM8F1D9 A0ACM8F1D9 RpL15 PTHR11847:SF4 RIBOSOMAL PROTEIN L15 LARGE RIBOSOMAL SUBUNIT PROTEIN EL15 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8038590|UniProtKB=A0ACM8EZ95 A0ACM8EZ95 LOC8038590 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8033649|UniProtKB=A0ACM8FAA1 A0ACM8FAA1 LOC8033649 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8035180|UniProtKB=A0ACM8E6U2 A0ACM8E6U2 LOC8035180 PTHR45727:SF11 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 cholesterol binding#GO:0015485;steroid binding#GO:0005496;lipid binding#GO:0008289;alcohol binding#GO:0043178;sterol binding#GO:0032934;small molecule binding#GO:0036094;binding#GO:0005488 homeostatic process#GO:0042592;multicellular organismal process#GO:0032501;digestion#GO:0007586;lipid transport#GO:0006869;lipid homeostasis#GO:0055088;macromolecule localization#GO:0033036;system process#GO:0003008;organic hydroxy compound transport#GO:0015850;sterol transport#GO:0015918;establishment of localization#GO:0051234;cholesterol homeostasis#GO:0042632;localization#GO:0051179;chemical homeostasis#GO:0048878;transport#GO:0006810;lipid localization#GO:0010876 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8040230|UniProtKB=A0ACM8DPI2 A0ACM8DPI2 LOC8040230 PTHR24339:SF28 HOMEOBOX PROTEIN EMX-RELATED E5-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;animal organ development#GO:0048513;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;nervous system development#GO:0007399;head development#GO:0060322;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;central nervous system development#GO:0007417;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC120844237|UniProtKB=A0ACM8EZ98 A0ACM8EZ98 LOC120844237 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115312031|UniProtKB=A0ACM8FSH8 A0ACM8FSH8 LOC115312031 PTHR19278:SF9 OROTATE PHOSPHORIBOSYLTRANSFERASE URIDINE 5'-MONOPHOSPHATE SYNTHASE carbon-carbon lyase activity#GO:0016830;pentosyltransferase activity#GO:0016763;catalytic activity#GO:0003824;transferase activity#GO:0016740;carboxy-lyase activity#GO:0016831;lyase activity#GO:0016829;glycosyltransferase activity#GO:0016757 nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;nucleoside monophosphate biosynthetic process#GO:0009124;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleobase-containing small molecule metabolic process#GO:0055086;pyrimidine nucleobase metabolic process#GO:0006206;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;pyrimidine-containing compound metabolic process#GO:0072527;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637 transferase#PC00220;metabolite interconversion enzyme#PC00262 De novo pyrimidine ribonucleotides biosythesis#P02740>Orotate phosphoribosyltransferase#P02922 IXOSC|EnsemblGenome=LOC8041999|UniProtKB=A0ACM8DU73 A0ACM8DU73 LOC8041999 PTHR24320:SF285 RETINOL DEHYDROGENASE RETINOL DEHYDROGENASE 14 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106 organophosphate biosynthetic process#GO:0090407;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120837782|UniProtKB=A0ACM8EIZ9 A0ACM8EIZ9 LOC120837782 PTHR11439:SF463 GAG-POL-RELATED RETROTRANSPOSON INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120841552|UniProtKB=A0ACM8ERY9 A0ACM8ERY9 LOC120841552 PTHR10579:SF178 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-LIKE ion channel#PC00133 IXOSC|EnsemblGenome=LOC8053363|UniProtKB=A0ACM8DQ07 A0ACM8DQ07 LOC8053363 PTHR23512:SF13 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 1 LYSOSOMAL DIPEPTIDE TRANSPORTER MFSD1 intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120843522|UniProtKB=A0ACM8EWB8 A0ACM8EWB8 LOC120843522 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC115331631|UniProtKB=A0ACM8F3H5 A0ACM8F3H5 LOC115331631 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115327458|UniProtKB=A0ACM8EGQ4 A0ACM8EGQ4 LOC115327458 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121833793|UniProtKB=A0ACM8FN19 A0ACM8FN19 PTHR14340:SF22 MICROFIBRIL-ASSOCIATED GLYCOPROTEIN 3 IG-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028872|UniProtKB=A0ACM8EI39 A0ACM8EI39 LOC8028872 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8029044|UniProtKB=A0ACM8EM82 A0ACM8EM82 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8028974|UniProtKB=A0ACM8FTC3 A0ACM8FTC3 LOC8028974 PTHR34008:SF2 REPETITIVE PROLINE-RICH CELL WALL PROTEIN 1 REPETITIVE PROLINE-RICH CELL WALL PROTEIN 1 IXOSC|EnsemblGenome=LOC115314451|UniProtKB=A0ACM8EN87 A0ACM8EN87 LOC115314451 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120839113|UniProtKB=A0ACM8EMD5 A0ACM8EMD5 LOC120839113 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8030462|UniProtKB=A0ACM8DH44 A0ACM8DH44 LOC8030462 PTHR11963:SF23 LEUCINE AMINOPEPTIDASE-RELATED CYTOSOL AMINOPEPTIDASE catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8024050|UniProtKB=A0ACM8E1L0 A0ACM8E1L0 Mcad PTHR43884:SF43 ACYL-COA DEHYDROGENASE GLUCURONOSYLTRANSFERASE oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;fatty acid catabolic process#GO:0009062;short-chain fatty acid catabolic process#GO:0019626;lipid oxidation#GO:0034440;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;fatty acid oxidation#GO:0019395;fatty acid beta-oxidation#GO:0006635;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid modification#GO:0030258;carboxylic acid catabolic process#GO:0046395;lipid catabolic process#GO:0016042;cellular process#GO:0009987;monocarboxylic acid catabolic process#GO:0072329 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8031226|UniProtKB=A0ACM8EBB9 A0ACM8EBB9 LOC8031226 PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;C4-dicarboxylate transmembrane transporter activity#GO:0015556;citrate transmembrane transporter activity#GO:0015137;succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310 cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;tricarboxylic acid transport#GO:0006842;citrate transport#GO:0015746;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8039335|UniProtKB=A0ACM8EDF4 A0ACM8EDF4 LOC8039335 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115320196|UniProtKB=A0ACM8FBL6 A0ACM8FBL6 spz4 PTHR23199:SF5 NEUROTROPHIN 1-RELATED PROTEIN SPAETZLE 4 molecular function activator activity#GO:0140677;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;receptor ligand activity#GO:0048018;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545 developmental process#GO:0032502;anatomical structure formation involved in morphogenesis#GO:0048646;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087;multicellular organism development#GO:0007275;immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;defense response to other organism#GO:0098542;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;system development#GO:0048731;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;central nervous system development#GO:0007417;response to stimulus#GO:0050896 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8035835|UniProtKB=A0ACM8FV55 A0ACM8FV55 Rdl PTHR18945:SF856 NEUROTRANSMITTER GATED ION CHANNEL GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT BETA excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;channel activity#GO:0015267 monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transport#GO:0006810;chloride transport#GO:0006821;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656;cellular process#GO:0009987;monoatomic anion transport#GO:0006820 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8024431|UniProtKB=A0ACM8FW26 A0ACM8FW26 LOC8024431 PTHR46698:SF3 CROSSVEINLESS 2 VWFC DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC121838183|UniProtKB=A0ACM8G732 A0ACM8G732 LOC121838183 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8029798|UniProtKB=A0ACM8ETR7 A0ACM8ETR7 LOC8029798 PTHR47666:SF6 PROTEIN VASCULAR ASSOCIATED DEATH 1, CHLOROPLASTIC TBC1 DOMAIN FAMILY MEMBER 9 IXOSC|EnsemblGenome=LOC120847837|UniProtKB=A0ACM8F4N5 A0ACM8F4N5 purple PTHR12589:SF10 PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE 6-PYRUVOYL TETRAHYDROBIOPTERIN SYNTHASE catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829 biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120848741|UniProtKB=A0ACM8F6C6 A0ACM8F6C6 LOC120848741 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120838538|UniProtKB=A0ACM8EK76 A0ACM8EK76 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836702|UniProtKB=A0ACM8G107 A0ACM8G107 LOC121836702 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8024928|UniProtKB=A0ACM8DNN0 A0ACM8DNN0 LOC8024928 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120850337|UniProtKB=A0ACM8F8K8 A0ACM8F8K8 LOC120850337 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309812|UniProtKB=A0ACM8EQ24 A0ACM8EQ24 LOC115309812 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8051912|UniProtKB=A0ACM8EJD9 A0ACM8EJD9 LOC8051912 PTHR13544:SF0 SELENOPROTEIN T THIOREDOXIN REDUCTASE-LIKE SELENOPROTEIN T antioxidant activity#GO:0016209;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 cellular homeostasis#GO:0019725;cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 IXOSC|EnsemblGenome=LOC8026464|UniProtKB=A0ACM8DHS4 A0ACM8DHS4 LOC8026464 PTHR42912:SF80 METHYLTRANSFERASE METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8037549|UniProtKB=A0ACM8DTQ9 A0ACM8DTQ9 IntS3 PTHR13587:SF7 INTEGRATOR COMPLEX SUBUNIT 3 INTEGRATOR COMPLEX SUBUNIT 3 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8053899|UniProtKB=A0ACM8DUY9 A0ACM8DUY9 LOC8053899 PTHR23065:SF7 PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 NOSTRIN, ISOFORM H membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886 cytoskeletal protein#PC00085;actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC121047409|UniProtKB=A0ACM8FGA5 A0ACM8FGA5 LOC121047409 PTHR12482:SF5 LIPASE ROG1-RELATED-RELATED DUF676 DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC115314312|UniProtKB=A0ACM8F0L7 A0ACM8F0L7 LOC115314312 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046296|UniProtKB=A0ACM8FTV7 A0ACM8FTV7 LOC121046296 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848216|UniProtKB=A0ACM8F5N3 A0ACM8F5N3 LOC120848216 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318985|UniProtKB=A0ACM8EQI5 A0ACM8EQI5 PhKgamma PTHR44167:SF18 OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED PHOSPHORYLASE KINASE protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 IXOSC|EnsemblGenome=LOC8051125|UniProtKB=A0ACM8EC34 A0ACM8EC34 Rab3 PTHR47980:SF19 LD44762P RAS-RELATED PROTEIN RAB-3 myosin binding#GO:0017022;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;establishment of localization#GO:0051234;cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192 secretory vesicle#GO:0099503;membrane#GO:0016020;presynapse#GO:0098793;cell periphery#GO:0071944;transport vesicle#GO:0030133;endomembrane system#GO:0012505;plasma membrane#GO:0005886;cytoplasm#GO:0005737;cell junction#GO:0030054;intracellular vesicle#GO:0097708;vesicle#GO:0031982;synaptic vesicle#GO:0008021;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;exocytic vesicle#GO:0070382;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120845775|UniProtKB=A0ACM8F1Q6 A0ACM8F1Q6 LOC120845775 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 macromolecule localization#GO:0033036;protein localization to Golgi apparatus#GO:0034067;intracellular protein localization#GO:0008104;localization#GO:0051179;protein localization to organelle#GO:0033365 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115328458|UniProtKB=A0ACM8E946 A0ACM8E946 Megf8 PTHR46376:SF5 LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1 MULTIPLE EPIDERMAL GROWTH FACTOR DOMAINS 8-LIKE PROTEIN DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC8028771|UniProtKB=A0ACM8FWZ1 A0ACM8FWZ1 LOC8028771 PTHR45638:SF7 CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A CYCLIC NUCLEOTIDE-GATED ION CHANNEL-LIKE, ISOFORM E ligand-gated ion channel#PC00141;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8044096|UniProtKB=A0ACM8E374 A0ACM8E374 LOC8044096 PTHR12271:SF140 POLY A POLYMERASE CID PAP -RELATED POLY(A) RNA POLYMERASE GLD2 transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;adenylyltransferase activity#GO:0070566;catalytic activity, acting on RNA#GO:0140098 regulation of mRNA metabolic process#GO:1903311;RNA 3'-end processing#GO:0031123;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;RNA processing#GO:0006396;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;RNA destabilization#GO:0050779;mRNA processing#GO:0006397;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;modification-dependent macromolecule catabolic process#GO:0043632;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;regulation of mRNA stability#GO:0043488;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;positive regulation of RNA metabolic process#GO:0051254;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;positive regulation of mRNA catabolic process#GO:0061014;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC115310672|UniProtKB=A0ACM8FKP7 A0ACM8FKP7 LOC115310672 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8053275|UniProtKB=A0ACM8E389 A0ACM8E389 LOC8053275 PTHR10199:SF100 THROMBOSPONDIN THROMBOSPONDIN, ISOFORM A extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8031049|UniProtKB=A0ACM8DMK5 A0ACM8DMK5 LOC8031049 PTHR11089:SF30 GTP-BINDING PROTEIN-RELATED GUANINE NUCLEOTIDE-BINDING PROTEIN-LIKE 3 HOMOLOG intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8034073|UniProtKB=A0ACM8DIV3 A0ACM8DIV3 LOC8034073 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;oxoacid metabolic process#GO:0043436;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8024086|UniProtKB=A0ACM8DHY3 A0ACM8DHY3 LOC8024086 PTHR11055:SF79 BIFUNCTIONAL 3'-PHOSPHOADENOSINE 5'-PHOSPHOSULFATE SYNTHASE PAPS SYNTHETASE, ISOFORM D phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate derivative metabolic process#GO:1901135;sulfur compound metabolic process#GO:0006790;ribose phosphate biosynthetic process#GO:0046390;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleotide biosynthetic process#GO:0009165;organophosphate biosynthetic process#GO:0090407;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;oxoacid metabolic process#GO:0043436 Sulfate assimilation#P02778>Sulfate adenylyltransferase#P03167 IXOSC|EnsemblGenome=LOC121834045|UniProtKB=A0ACM8FP90 A0ACM8FP90 LOC121834045 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8039660|UniProtKB=A0ACM8EEY0 A0ACM8EEY0 LOC8039660 PTHR42780:SF1 SOLEUCYL-TRNA SYNTHETASE ISOLEUCINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070 cytosol#GO:0005829;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC115329186|UniProtKB=A0ACM8E972 A0ACM8E972 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8038011|UniProtKB=A0ACM8EUU4 A0ACM8EUU4 LOC8038011 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120841783|UniProtKB=A0ACM8ESC9 A0ACM8ESC9 LOC120841783 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121837255|UniProtKB=A0ACM8G3Y4 A0ACM8G3Y4 LOC121837255 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040447|UniProtKB=A0ACM8DWN4 A0ACM8DWN4 LOC8040447 PTHR21245:SF2 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN RNA-BINDING PROTEIN 18-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8028066|UniProtKB=A0ACM8G8L1 A0ACM8G8L1 LOC8028066 PTHR12450:SF26 DENTIN MATRIX PROTEIN 4 PROTEIN FAM20 EXTRACELLULAR SERINE_THREONINE PROTEIN CG31145 transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;extracellular region#GO:0005576;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8037725|UniProtKB=A0ACM8DMG4 A0ACM8DMG4 LOC8037725 PTHR12305:SF100 PHOSPHATASE WITH HOMOLOGY TO TENSIN PHOSPHATIDYLINOSITOL 3,4,5-TRISPHOSPHATE 3-PHOSPHATASE AND DUAL-SPECIFICITY PROTEIN PHOSPHATASE PTEN phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cell cycle#GO:0051726;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0051896 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;cell projection#GO:0042995;membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;nucleus#GO:0005634 protein phosphatase#PC00195;protein modifying enzyme#PC00260 Hypoxia response via HIF activation#P00030>PTEN#P00824;p53 pathway#P00059>PTEN#G01579;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#G04675;p53 pathway#P00059>PTEN#P01480;PI3 kinase pathway#P00048>PTEN#P01189;p53 pathway feedback loops 2#P04398>PTEN#G04714;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PTEN#P00905;p53 pathway feedback loops 2#P04398>PTEN#P04658 IXOSC|EnsemblGenome=LOC8026587|UniProtKB=A0ACM8DSZ3 A0ACM8DSZ3 Taz PTHR12497:SF8 TAZ PROTEIN TAFAZZIN TAFAZZIN acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phosphatidylglycerol metabolic process#GO:0046471;cellular component organization#GO:0016043;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;mitochondrion organization#GO:0007005;membrane organization#GO:0061024;glycerophospholipid metabolic process#GO:0006650;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;mitochondrial membrane organization#GO:0007006;organelle organization#GO:0006996;organophosphate metabolic process#GO:0019637 mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121838508|UniProtKB=A0ACM8G8I0 A0ACM8G8I0 LOC121838508 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121838426|UniProtKB=A0ACM8G8X6 A0ACM8G8X6 Arl4 PTHR11711:SF186 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 11 nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein#PC00020 Huntington disease#P00029>ARF#P00786 IXOSC|EnsemblGenome=LOC8042136|UniProtKB=A0ACM8DKV4 A0ACM8DKV4 LOC8042136 PTHR28080:SF1 PEROXISOMAL BIOGENESIS FACTOR 3 PEROXISOMAL BIOGENESIS FACTOR 3 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein localization to membrane#GO:0072657;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;peroxisome organization#GO:0007031;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;peroxisomal transport#GO:0043574;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization to membrane#GO:0090150;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8031950|UniProtKB=A0ACM8EE44 A0ACM8EE44 LOC8031950 PTHR21258:SF61 DOCKING PROTEIN RELATED DOCKING PROTEIN 5-LIKE ISOFORM X1 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8050863|UniProtKB=A0ACM8E703 A0ACM8E703 LOC8050863 PTHR45906:SF1 ALPHA-N-ACETYL-NEURAMINYL-2,3-BETA-GALACTOSYL-1, 3-N-ACETYL-GALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE-LIKE ALPHA-N-ACETYL-NEURAMINYL-2,3-BETA-GALACTOSYL-1, 3-N-ACETYL-GALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE-LIKE ISOFORM X1 IXOSC|EnsemblGenome=LOC115316329|UniProtKB=A0ACM8FB20 A0ACM8FB20 LOC115316329 PTHR24264:SF87 TRYPSIN-RELATED SERINE PROTEASE 30 ISOFORM X1 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8053686|UniProtKB=A0ACM8EPI5 A0ACM8EPI5 LOC8053686 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC121837874|UniProtKB=A0ACM8G6U1 A0ACM8G6U1 LOC121837874 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115328622|UniProtKB=A0ACM8E8G0 A0ACM8E8G0 mre11 PTHR10139:SF9 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 DOUBLE-STRAND BREAK REPAIR PROTEIN MRE11 hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 negative regulation of cell cycle G2/M phase transition#GO:1902750;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;negative regulation of mitotic cell cycle phase transition#GO:1901991;cellular process#GO:0009987;signal transduction#GO:0007165;meiotic DNA double-strand break formation#GO:0042138;organelle organization#GO:0006996;mitotic intra-S DNA damage checkpoint signaling#GO:0031573;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;telomere organization#GO:0032200;regulation of G2/M transition of mitotic cell cycle#GO:0010389;sexual reproduction#GO:0019953;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;double-strand break repair#GO:0006302;negative regulation of cell cycle#GO:0045786;DNA recombination#GO:0006310;metabolic process#GO:0008152;regulation of cell cycle process#GO:0010564;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;response to stress#GO:0006950;mitotic G2 DNA damage checkpoint signaling#GO:0007095;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;cellular response to stress#GO:0033554;signaling#GO:0023052;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;telomere maintenance#GO:0000723;double-strand break repair via nonhomologous end joining#GO:0006303;negative regulation of cell cycle process#GO:0010948;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;DNA damage checkpoint signaling#GO:0000077;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;mitotic G2/M transition checkpoint#GO:0044818;regulation of cell cycle G2/M phase transition#GO:1902749;DNA integrity checkpoint signaling#GO:0031570;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;mitotic DNA damage checkpoint signaling#GO:0044773;nucleic acid metabolic process#GO:0090304;mitotic cell cycle checkpoint signaling#GO:0007093 chromosome#GO:0005694;site of double-strand break#GO:0035861;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115320217|UniProtKB=A0ACM8FE59 A0ACM8FE59 LOC115320217 PTHR13563:SF13 TRNA (GUANINE-9-) METHYLTRANSFERASE TRNA (GUANINE(9)-N(1))-METHYLTRANSFERASE TRMT10A RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115325732|UniProtKB=A0ACM8E515 A0ACM8E515 LOC115325732 PTHR31635:SF196 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120837610|UniProtKB=A0ACM8EHW8 A0ACM8EHW8 LOC120837610 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC121047269|UniProtKB=A0ACM8FEL2 A0ACM8FEL2 LOC121047269 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8031022|UniProtKB=A0ACM8FE40 A0ACM8FE40 LOC8031022 PTHR10606:SF44 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;transferase activity#GO:0016740;catalytic activity#GO:0003824;carbohydrate kinase activity#GO:0019200;phosphoric ester hydrolase activity#GO:0042578;sugar-phosphatase activity#GO:0050308;phosphotransferase activity, alcohol group as acceptor#GO:0016773;hydrolase activity#GO:0016787 phosphorus metabolic process#GO:0006793;metabolic process#GO:0008152;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 phosphatase#PC00181;hydrolase#PC00121;carbohydrate phosphatase#PC00066 IXOSC|EnsemblGenome=LOC8027049|UniProtKB=A0ACM8FDS7 A0ACM8FDS7 knk PTHR24036:SF16 SKELETOR-RELATED KNICKKOPF transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8031616|UniProtKB=A0ACM8FUA4 A0ACM8FUA4 LOC8031616 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836380|UniProtKB=A0ACM8FY04 A0ACM8FY04 LOC121836380 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8038589|UniProtKB=A0ACM8DK76 A0ACM8DK76 LOC8038589 PTHR21051:SF4 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 CAMP-RESPONSIVE ELEMENT-BINDING PROTEIN-LIKE 2 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8037845|UniProtKB=A0ACM8E7U5 A0ACM8E7U5 LOC8037845 PTHR16830:SF24 SH2 CONTAINING ADAPTOR PRAM-1 RELATED FYN-BINDING PROTEIN 1 immune system process#GO:0002376;cellular localization#GO:0051641;immune response-regulating signaling pathway#GO:0002764;regulation of biological process#GO:0050789;integrin-mediated signaling pathway#GO:0007229;protein localization to membrane#GO:0072657;signaling#GO:0023052;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;protein localization to cell periphery#GO:1990778;immune response-activating signaling pathway#GO:0002757;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;activation of immune response#GO:0002253;positive regulation of immune system process#GO:0002684;antigen receptor-mediated signaling pathway#GO:0050851;regulation of immune response#GO:0050776;localization within membrane#GO:0051668;localization#GO:0051179;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;protein localization to plasma membrane#GO:0072659;immune response-activating cell surface receptor signaling pathway#GO:0002429;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;positive regulation of immune response#GO:0050778;T cell receptor signaling pathway#GO:0050852;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;immune response-regulating cell surface receptor signaling pathway#GO:0002768;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8043854|UniProtKB=A0ACM8DL62 A0ACM8DL62 LOC8043854 PTHR45695:SF9 LEUCOKININ RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8038356|UniProtKB=A0ACM8EEM2 A0ACM8EEM2 MCU PTHR13462:SF10 CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL CALCIUM UNIPORTER PROTEIN, MITOCHONDRIAL secondary active transmembrane transporter activity#GO:0015291;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;calcium ion transmembrane transporter activity#GO:0015085 inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;homeostatic process#GO:0042592;metal ion transport#GO:0030001;mitochondrial calcium ion homeostasis#GO:0051560;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;calcium channel complex#GO:0034704;mitochondrion#GO:0005739;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;monoatomic ion channel complex#GO:0034702;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle membrane#GO:0031090;transporter complex#GO:1990351;inner mitochondrial membrane protein complex#GO:0098800;cation channel complex#GO:0034703 IXOSC|EnsemblGenome=LOC8031452|UniProtKB=A0ACM8DQV4 A0ACM8DQV4 PTHR23289:SF2 CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 HEME A SYNTHASE COX15 chaperone#PC00072 Vitamin D metabolism and pathway#P04396>FDX#P04607 IXOSC|EnsemblGenome=LOC115316227|UniProtKB=A0ACM8DVT2 A0ACM8DVT2 LOC115316227 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC8038720|UniProtKB=A0ACM8FLY1 A0ACM8FLY1 LOC8038720 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8053728|UniProtKB=A0ACM8DW97 A0ACM8DW97 LOC8053728 PTHR21461:SF83 GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN GLYCOSYLTRANSFERASE FAMILY 92 PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8053349|UniProtKB=A0ACM8EXU2 A0ACM8EXU2 LOC8053349 PTHR11640:SF31 NEPHRIN MIP08606P cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 cell-cell junction#GO:0005911;membrane#GO:0016020;cell periphery#GO:0071944;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;anchoring junction#GO:0070161 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8053231|UniProtKB=A0ACM8ESU8 A0ACM8ESU8 LOC8053231 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;sodium ion transport#GO:0006814;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8053863|UniProtKB=A0ACM8FNB0 A0ACM8FNB0 LOC8053863 PTHR23043:SF26 HYPOXIA-INDUCIBLE FACTOR 1 ALPHA PROTEIN TRACHEALESS sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8053551|UniProtKB=A0ACM8EBJ8 A0ACM8EBJ8 RpS18 PTHR10871:SF3 30S RIBOSOMAL PROTEIN S13/40S RIBOSOMAL PROTEIN S18 SMALL RIBOSOMAL SUBUNIT PROTEIN US13 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8051591|UniProtKB=A0ACM8ES02 A0ACM8ES02 LOC8051591 PTHR18945:SF908 NEUROTRANSMITTER GATED ION CHANNEL HISTAMINE-GATED CHLORIDE CHANNEL ALPHA1 SUBUNIT extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;chloride transmembrane transport#GO:1902476;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698;chloride transport#GO:0006821;transport#GO:0006810;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transport#GO:0006820;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC8024827|UniProtKB=A0ACM8FCR7 A0ACM8FCR7 LOC8024827 PTHR10071:SF337 TRANSCRIPTION FACTOR GATA FAMILY MEMBER BOX A-BINDING FACTOR-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell fate commitment#GO:0045165;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8043661|UniProtKB=A0ACM8DWU0 A0ACM8DWU0 LOC8043661 PTHR15681:SF1 MAD2L1-BINDING PROTEIN MAD2L1-BINDING PROTEIN intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120840790|UniProtKB=A0ACM8EQE8 A0ACM8EQE8 LOC120840790 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832856|UniProtKB=A0ACM8FQG2 A0ACM8FQG2 PTHR22891:SF111 EUKARYOTIC TRANSLATION INITIATION FACTOR 2C PROTEIN ARGONAUTE-3 RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA binding#GO:0003723;nuclease activity#GO:0004518;binding#GO:0005488;nucleic acid binding#GO:0003676 negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 intracellular organelle#GO:0043229;P granule#GO:0043186;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;supramolecular complex#GO:0099080 translational protein#PC00263;translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC115333056|UniProtKB=A0ACM8EFB5 A0ACM8EFB5 LOC115333056 PTHR11042:SF185 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED WEE1-LIKE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;protein tyrosine kinase activity#GO:0004713;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115319715|UniProtKB=A0ACM8F6F1 A0ACM8F6F1 LOC115319715 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8034507|UniProtKB=A0ACM8DSK9 A0ACM8DSK9 LOC8034507 PTHR14149:SF14 RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF CALPONIN-HOMOLOGY (CH) DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;calmodulin binding#GO:0005516;cytoskeletal protein binding#GO:0008092 supramolecular fiber organization#GO:0097435;cytoskeleton-dependent cytokinesis#GO:0061640;cortical actin cytoskeleton organization#GO:0030866;mitotic cytokinetic process#GO:1902410;cytokinetic process#GO:0032506;actin filament-based process#GO:0030029;cytokinesis#GO:0000910;cortical cytoskeleton organization#GO:0030865;actomyosin structure organization#GO:0031032;mitotic cell cycle#GO:0000278;mitotic cytokinesis#GO:0000281;actin cytoskeleton organization#GO:0030036;cell cycle process#GO:0022402;cell division#GO:0051301;cell cycle#GO:0007049;cellular component organization#GO:0016043;actin filament organization#GO:0007015;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;actomyosin contractile ring assembly#GO:0000915 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cell cortex#GO:0005938;cell periphery#GO:0071944 GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC120844082|UniProtKB=A0ACM8EXV1 A0ACM8EXV1 LOC120844082 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8029952|UniProtKB=A0ACM8DZM9 A0ACM8DZM9 LOC8029952 PTHR11902:SF1 ENOLASE ENOLASE carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824;phosphopyruvate hydratase activity#GO:0004634 purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleoside diphosphate metabolic process#GO:0009132;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;primary metabolic process#GO:0044238;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;pyruvate metabolic process#GO:0006090;pyridine nucleotide catabolic process#GO:0019364;small molecule metabolic process#GO:0044281;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;carboxylic acid metabolic process#GO:0019752;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;purine-containing compound catabolic process#GO:0072523;ADP catabolic process#GO:0046032;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496 cytosol#GO:0005829;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;lyase#PC00144 Glycolysis#P00024>Enolase#P00678 IXOSC|EnsemblGenome=LOC8024759|UniProtKB=A0ACM8E1R8 A0ACM8E1R8 LOC8024759 PTHR28631:SF1 UPF0692 PROTEIN C19ORF54 ACTIN MATURATION PROTEASE catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;aminopeptidase activity#GO:0004177 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 IXOSC|EnsemblGenome=LOC120841647|UniProtKB=A0ACM8ES04 A0ACM8ES04 LOC120841647 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029406|UniProtKB=A0ACM8FL04 A0ACM8FL04 LOC8029406 PTHR48023:SF6 D-XYLOSE-PROTON SYMPORTER-LIKE 2 D-XYLOSE-PROTON SYMPORTER-LIKE 3, CHLOROPLASTIC transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119 carbohydrate transport#GO:0008643;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;D-glucose transmembrane transport#GO:1904659;cellular process#GO:0009987;carbohydrate transmembrane transport#GO:0034219 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8028427|UniProtKB=A0ACM8EZM4 A0ACM8EZM4 LOC8028427 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE nucleotidase activity#GO:0008252;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;purine ribonucleoside monophosphate metabolic process#GO:0009167;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine ribonucleotide catabolic process#GO:0009154;purine-containing compound metabolic process#GO:0072521;purine-containing compound catabolic process#GO:0072523;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC8052961|UniProtKB=A0ACM8DN91 A0ACM8DN91 LOC8052961 PTHR44269:SF2 DEHYDROGENASE/REDUCTASE SDR FAMILY MEMBER 7-RELATED IP05441P catalytic activity#GO:0003824;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8052335|UniProtKB=A0ACM8DM26 A0ACM8DM26 LOC8052335 PTHR20842:SF0 PROTEASE S51 ALPHA-ASPARTYL DIPEPTIDASE DIPEPTIDASE E serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8025125|UniProtKB=A0ACM8DUH0 A0ACM8DUH0 mtTFB2 PTHR11727:SF13 DIMETHYLADENOSINE TRANSFERASE DIMETHYLADENOSINE TRANSFERASE 2, MITOCHONDRIAL transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;rRNA methyltransferase activity#GO:0008649;RNA methyltransferase activity#GO:0008173;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;N-methyltransferase activity#GO:0008170;transcription regulator activity#GO:0140110;rRNA (adenine) methyltransferase activity#GO:0016433;catalytic activity, acting on a rRNA#GO:0140102 mitochondrial RNA metabolic process#GO:0000959;RNA methylation#GO:0001510;macromolecule modification#GO:0043412;mitochondrial gene expression#GO:0140053;rRNA processing#GO:0006364;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;rRNA metabolic process#GO:0016072;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mitochondrial transcription#GO:0006390;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;RNA modification#GO:0009451;methylation#GO:0032259;RNA metabolic process#GO:0016070;rRNA modification#GO:0000154;DNA-templated transcription initiation#GO:0006352;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;rRNA methylation#GO:0031167;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396 intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 RNA methyltransferase#PC00033;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120846310|UniProtKB=A0ACM8F1A4 A0ACM8F1A4 LOC120846310 PTHR22666:SF3 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 MYB_SANT-LIKE DNA-BINDING DOMAIN-CONTAINING PROTEIN 1 regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121048703|UniProtKB=A0ACM8FJ15 A0ACM8FJ15 LOC121048703 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8029220|UniProtKB=A0ACM8G8Q8 A0ACM8G8Q8 LOC8029220 PTHR11177:SF399 CHITINASE CHITINASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115318769|UniProtKB=A0ACM8DYD8 A0ACM8DYD8 LOC115318769 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8025283|UniProtKB=A0ACM8DJ50 A0ACM8DJ50 Ipp PTHR43028:SF3 3'(2'),5'-BISPHOSPHATE NUCLEOTIDASE 1 INOSITOL POLYPHOSPHATE 1-PHOSPHATASE hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 signaling#GO:0023052;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;anterograde trans-synaptic signaling#GO:0098916;regulation of biological process#GO:0050789;cellular process#GO:0009987;synaptic signaling#GO:0099536;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8031824|UniProtKB=A0ACM8EFA3 A0ACM8EFA3 LOC8031824 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115325278|UniProtKB=A0ACM8EVA4 A0ACM8EVA4 LOC115325278 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115312155|UniProtKB=A0ACM8FG59 A0ACM8FG59 LOC115312155 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844394|UniProtKB=A0ACM8EYL9 A0ACM8EYL9 LOC120844394 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115315461|UniProtKB=A0ACM8F089 A0ACM8F089 RpI1 PTHR19376:SF11 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA1 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleolar large rRNA transcription by RNA polymerase I#GO:0042790;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;transcription by RNA polymerase I#GO:0006360;rRNA transcription#GO:0009303 RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115325517|UniProtKB=A0ACM8EN70 A0ACM8EN70 LOC115325517 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8031246|UniProtKB=A0ACM8DI20 A0ACM8DI20 LOC8031246 PTHR43146:SF1 CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE CANCER-RELATED NUCLEOSIDE-TRIPHOSPHATASE phosphatase#PC00181;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8037887|UniProtKB=A0ACM8DZK1 A0ACM8DZK1 Rcc1 PTHR45982:SF1 REGULATOR OF CHROMOSOME CONDENSATION HDC11342-RELATED regulation of microtubule-based process#GO:0032886;regulation of spindle assembly#GO:0090169;regulation of mitotic spindle organization#GO:0060236;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;regulation of cell cycle#GO:0051726;regulation of cellular component biogenesis#GO:0044087;regulation of spindle organization#GO:0090224;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular process#GO:0050794;regulation of mitotic spindle assembly#GO:1901673;regulation of organelle assembly#GO:1902115;regulation of mitotic cell cycle#GO:0007346;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of microtubule cytoskeleton organization#GO:0070507 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8053581|UniProtKB=A0ACM8DL84 A0ACM8DL84 LOC8053581 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8052303|UniProtKB=A0ACM8E278 A0ACM8E278 beta-PheRS PTHR10947:SF0 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 PHENYLALANINE--TRNA LIGASE BETA SUBUNIT catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8052641|UniProtKB=A0ACM8FHJ1 A0ACM8FHJ1 LOC8052641 PTHR46560:SF14 CYPHER, ISOFORM B MINIATURE developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;anatomical structure development#GO:0048856;cell morphogenesis#GO:0000902 plasma membrane#GO:0005886;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;apical part of cell#GO:0045177;cell periphery#GO:0071944;apical plasma membrane#GO:0016324;membrane#GO:0016020 IXOSC|EnsemblGenome=ISCI013552|UniProtKB=B7QIN3 B7QIN3 ISCW013552 PTHR28622:SF1 SMALL INTEGRAL MEMBRANE PROTEIN 7 SMALL INTEGRAL MEMBRANE PROTEIN 7 IXOSC|EnsemblGenome=LOC121837827|UniProtKB=A0ACM8G6C5 A0ACM8G6C5 LOC121837827 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC8036679|UniProtKB=A0ACM8FUT0 A0ACM8FUT0 LOC8036679 PTHR10177:SF584 CYCLINS CYCLIN G cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;kinase regulator activity#GO:0019207;molecular function regulator activity#GO:0098772;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC120843887|UniProtKB=A0ACM8G8I2 A0ACM8G8I2 LOC120843887 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849472|UniProtKB=A0ACM8F8U2 A0ACM8F8U2 LOC120849472 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120838083|UniProtKB=A0ACM8EK08 A0ACM8EK08 LOC120838083 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8029507|UniProtKB=A0ACM8DI84 A0ACM8DI84 LOC8029507 PTHR12604:SF4 KU AUTOANTIGEN DNA HELICASE DNA REPAIR PROTEIN KU80 nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162 cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;telomere organization#GO:0032200;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;double-strand break repair via nonhomologous end joining#GO:0006303;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC115326565|UniProtKB=A0ACM8E6W5 A0ACM8E6W5 Ilk PTHR44329:SF57 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED SCAFFOLD PROTEIN ILK catalytic activity#GO:0003824;transferase activity#GO:0016740;molecular adaptor activity#GO:0060090;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity, acting on a protein#GO:0140096;binding#GO:0005488;signaling receptor binding#GO:0005102;protein-macromolecule adaptor activity#GO:0030674;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 signal transduction#GO:0007165;cellular process#GO:0009987;biological regulation#GO:0065007;developmental process#GO:0032502;substrate adhesion-dependent cell spreading#GO:0034446;cell surface receptor signaling pathway#GO:0007166;cellular developmental process#GO:0048869;integrin-mediated signaling pathway#GO:0007229;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;cell adhesion#GO:0007155;cell-matrix adhesion#GO:0007160;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154 anchoring junction#GO:0070161;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Integrin signalling pathway#P00034>ILK#P00935 IXOSC|EnsemblGenome=LOC115325301|UniProtKB=A0ACM8G4H8 A0ACM8G4H8 LOC115325301 PTHR46599:SF9 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED 4-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115330547|UniProtKB=A0ACM8F7B6 A0ACM8F7B6 LOC115330547 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120845302|UniProtKB=A0ACM8G7W0 A0ACM8G7W0 LOC120845302 PTHR33426:SF52 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028714|UniProtKB=A0ACM8ECK7 A0ACM8ECK7 LOC8028714 PTHR23302:SF24 TRANSMEMBRANE CHANNEL-RELATED TMC DOMAIN-CONTAINING PROTEIN gated channel activity#GO:0022836;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ion channel#PC00133 IXOSC|EnsemblGenome=LOC8029108|UniProtKB=A0ACM8E2C4 A0ACM8E2C4 LOC8029108 PTHR10985:SF77 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED PROTEIN HAIRY sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cell development#GO:0060284;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of cell differentiation#GO:0045595;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;regulation of developmental process#GO:0050793;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of neurogenesis#GO:0050767;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;pattern specification process#GO:0007389;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;anterior/posterior pattern specification#GO:0009952;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of multicellular organismal development#GO:2000026;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 IXOSC|EnsemblGenome=LOC8042454|UniProtKB=A0ACM8EIR4 A0ACM8EIR4 LOC8042454 PTHR23055:SF167 CALCIUM BINDING PROTEINS EF-HAND DOMAIN-CONTAINING PROTEIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC120847535|UniProtKB=A0ACM8F4E0 A0ACM8F4E0 LOC120847535 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 IXOSC|EnsemblGenome=LOC8031426|UniProtKB=A0ACM8DMP6 A0ACM8DMP6 Tfb4 PTHR12831:SF0 TRANSCRIPTION INITIATION FACTOR IIH TFIIH , POLYPEPTIDE 3-RELATED GENERAL TRANSCRIPTION FACTOR IIH SUBUNIT 3 macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA repair#GO:0006281;transcription by RNA polymerase II#GO:0006366;DNA damage response#GO:0006974;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;transcription initiation at RNA polymerase II promoter#GO:0006367;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;DNA-templated transcription initiation#GO:0006352;response to stimulus#GO:0050896;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716 transferase complex#GO:1990234;transcription factor TFIIH core complex#GO:0000439;intracellular protein-containing complex#GO:0140535;protein kinase complex#GO:1902911;transcription regulator complex#GO:0005667;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;RNA polymerase II transcription regulator complex#GO:0090575;membrane-enclosed lumen#GO:0031974;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transcription factor TFIIH holo complex#GO:0005675;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 general transcription factor#PC00259;RNA metabolism protein#PC00031 Transcription regulation by bZIP transcription factor#P00055>TFIIH complex#P01392;General transcription regulation#P00023>TFIIH complex#P00664 IXOSC|EnsemblGenome=LOC8026674|UniProtKB=A0ACM8DYS7 A0ACM8DYS7 LOC8026674 PTHR21017:SF17 NIPSNAP-RELATED PROTEIN NIPSNAP IXOSC|EnsemblGenome=LOC115311394|UniProtKB=A0ACM8FZ60 A0ACM8FZ60 LOC115311394 PTHR43372:SF4 FATTY-ACID AMIDE HYDROLASE FATTY-ACID AMIDE HYDROLASE 2 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120847016|UniProtKB=A0ACM8F2Y1 A0ACM8F2Y1 LOC120847016 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8052500|UniProtKB=A0ACM8FHT9 A0ACM8FHT9 Shmt PTHR11680:SF59 SERINE HYDROXYMETHYLTRANSFERASE SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;heterocyclic compound binding#GO:1901363;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167 cellular process#GO:0009987;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;proteinogenic amino acid biosynthetic process#GO:0170038;carboxylic acid biosynthetic process#GO:0046394;modified amino acid metabolic process#GO:0006575;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;tetrahydrofolate metabolic process#GO:0046653 nucleus#GO:0005634;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 Serine glycine biosynthesis#P02776>Glycine hydroxymethyltransferase#P03158 IXOSC|EnsemblGenome=LOC8050981|UniProtKB=A0ACM8E5D4 A0ACM8E5D4 veli PTHR14063:SF10 PROTEIN LIN-7 HOMOLOG PROTEIN LIN-7 HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 regulation of biological process#GO:0050789;signaling#GO:0023052;export from cell#GO:0140352;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;establishment of organelle localization#GO:0051656;regulation of synapse organization#GO:0050807;secretion by cell#GO:0032940;regulation of biological quality#GO:0065008;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic vesicle transport#GO:0048489;neurotransmitter transport#GO:0006836;establishment of vesicle localization#GO:0051650;synaptic vesicle localization#GO:0097479;regulation of growth#GO:0040008;chemical synaptic transmission#GO:0007268;signal release from synapse#GO:0099643;regulation of developmental process#GO:0050793;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of cell junction assembly#GO:1901888;signal release#GO:0023061;trans-synaptic signaling#GO:0099537;organelle localization#GO:0051640;cell communication#GO:0007154;localization#GO:0051179;secretion#GO:0046903;regulation of synapse structure or activity#GO:0050803;vesicle localization#GO:0051648;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;neurotransmitter secretion#GO:0007269;regulation of synapse assembly#GO:0051963;transport#GO:0006810;establishment of localization#GO:0051234 cell periphery#GO:0071944;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;synapse#GO:0045202;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161;cell junction#GO:0030054 cell junction protein#PC00070 IXOSC|EnsemblGenome=LOC8029894|UniProtKB=A0ACM8EBB6 A0ACM8EBB6 LOC8029894 PTHR43720:SF2 2-AMINOMUCONIC SEMIALDEHYDE DEHYDROGENASE ALDEHYDE DEHYDROGENASE DOMAIN-CONTAINING PROTEIN oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC8028347|UniProtKB=A0ACM8DU48 A0ACM8DU48 MFS10 PTHR11662:SF462 SOLUTE CARRIER FAMILY 17 FI19708P1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8029273|UniProtKB=A0ACM8DHW0 A0ACM8DHW0 LOC8029273 PTHR45751:SF11 COPINE FAMILY PROTEIN 1 COPINE FAMILY PROTEIN 1 acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842 post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC8040050|UniProtKB=A0ACM8E261 A0ACM8E261 PTHR16056:SF16 REGULATOR OF MICROTUBULE DYNAMICS PROTEIN REGULATOR OF MICROTUBULE DYNAMICS PROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 mitochondrion#GO:0005739;spindle pole#GO:0000922;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;spindle microtubule#GO:0005876;microtubule#GO:0005874;mitotic spindle pole#GO:0097431;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoskeleton#GO:0005856;spindle#GO:0005819;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC120840301|UniProtKB=A0ACM8EN53 A0ACM8EN53 LOC120840301 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115309147|UniProtKB=A0ACM8F6M5 A0ACM8F6M5 LOC115309147 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC115311139|UniProtKB=A0ACM8FLS4 A0ACM8FLS4 LOC115311139 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314119|UniProtKB=A0ACM8DTG2 A0ACM8DTG2 LOC115314119 PTHR11177:SF408 CHITINASE ACIDIC MAMMALIAN CHITINASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;chitin catabolic process#GO:0006032;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115309271|UniProtKB=A0ACM8EIE6 A0ACM8EIE6 LOC115309271 PTHR11785:SF516 AMINO ACID TRANSPORTER AMINO ACID PERMEASE_ SLC12A DOMAIN-CONTAINING PROTEIN carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;amino acid transmembrane transporter activity#GO:0015171;L-amino acid transmembrane transporter activity#GO:0015179 amino acid transport#GO:0006865;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8051292|UniProtKB=A0ACM8E1F4 A0ACM8E1F4 Prp4k PTHR24058:SF103 DUAL SPECIFICITY PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PRP4 HOMOLOG protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120840842|UniProtKB=A0ACM8EQE2 A0ACM8EQE2 LOC120840842 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8053519|UniProtKB=A0ACM8EBZ7 A0ACM8EBZ7 LOC8053519 PTHR11640:SF154 NEPHRIN IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule binding#GO:0050839;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;anchoring junction#GO:0070161;cell junction#GO:0030054;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8035795|UniProtKB=A0ACM8E033 A0ACM8E033 LOC8035795 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120842326|UniProtKB=A0ACM8ETJ0 A0ACM8ETJ0 LOC120842326 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850182|UniProtKB=A0ACM8F9N9 A0ACM8F9N9 LOC120850182 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839839|UniProtKB=A0ACM8ENS8 A0ACM8ENS8 LOC120839839 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;microbody#GO:0042579;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115311088|UniProtKB=A0ACM8EX01 A0ACM8EX01 LOC115311088 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8041549|UniProtKB=A0ACM8DKQ5 A0ACM8DKQ5 LOC8041549 PTHR14107:SF24 WD REPEAT PROTEIN WD REPEAT-CONTAINING PROTEIN 20 HOMOLOG enzyme activator activity#GO:0008047;peptidase activator activity#GO:0016504;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of protein catabolic process#GO:0042177;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;negative regulation of cellular process#GO:0048523;regulation of catabolic process#GO:0009894;negative regulation of ubiquitin-dependent protein catabolic process#GO:2000059;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121833106|UniProtKB=A0ACM8FI90 A0ACM8FI90 LOC121833106 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308955|UniProtKB=A0ACM8G0J6 A0ACM8G0J6 LOC115308955 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8024204|UniProtKB=A0ACM8DYI3 A0ACM8DYI3 LOC8024204 PTHR28624:SF1 COILED-COIL DOMAIN-CONTAINING PROTEIN 51 MITOCHONDRIAL POTASSIUM CHANNEL IXOSC|EnsemblGenome=LOC115319052|UniProtKB=A0ACM8DZI5 A0ACM8DZI5 LOC115319052 PTHR10969:SF37 MICROTUBULE-ASSOCIATED PROTEINS 1A/1B LIGHT CHAIN 3-RELATED PROTEIN LGG-2 ubiquitin-like protein ligase binding#GO:0044389;phospholipid binding#GO:0005543;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;ubiquitin protein ligase binding#GO:0031625;binding#GO:0005488;microtubule binding#GO:0008017;enzyme binding#GO:0019899;protein binding#GO:0005515;lipid binding#GO:0008289 cellular response to stress#GO:0033554;organelle assembly#GO:0070925;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component disassembly#GO:0022411;cellular response to stimulus#GO:0051716;cellular component organization#GO:0016043;response to starvation#GO:0042594;protein-containing complex disassembly#GO:0032984;catabolic process#GO:0009056;response to stimulus#GO:0050896;cellular response to nutrient levels#GO:0031669;autophagosome maturation#GO:0097352;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;cellular response to starvation#GO:0009267;protein-containing complex organization#GO:0043933;autophagosome assembly#GO:0000045;mitophagy#GO:0000423;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;autophagosome organization#GO:1905037;autophagy#GO:0006914;response to stress#GO:0006950;cellular component biogenesis#GO:0044085;response to nutrient levels#GO:0031667;organelle organization#GO:0006996;macroautophagy#GO:0016236;cellular component assembly#GO:0022607 membrane#GO:0016020;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;autophagosome membrane#GO:0000421;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;vacuolar membrane#GO:0005774 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166;microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC121047473|UniProtKB=A0ACM8FEW9 A0ACM8FEW9 LOC121047473 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8052689|UniProtKB=A0ACM8DT91 A0ACM8DT91 PTHR12611:SF0 PUR-TRANSCRIPTIONAL ACTIVATOR PURINE-RICH BINDING PROTEIN-ALPHA, ISOFORM B DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8027036|UniProtKB=A0ACM8ELC1 A0ACM8ELC1 LOC8027036 PTHR48097:SF9 L-THREONINE ALDOLASE-RELATED L-THREONINE ALDOLASE catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830;lyase activity#GO:0016829;aldehyde-lyase activity#GO:0016832 proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 lyase#PC00144;aldolase#PC00044 IXOSC|EnsemblGenome=LOC8032470|UniProtKB=A0ACM8DYY6 A0ACM8DYY6 LOC8032470 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120849373|UniProtKB=A0ACM8F7M9 A0ACM8F7M9 LOC120849373 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811 cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120836111|UniProtKB=A0ACM8EUI8 A0ACM8EUI8 LOC120836111 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120842996|UniProtKB=A0ACM8EV45 A0ACM8EV45 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035542|UniProtKB=A0ACM8FXI7 A0ACM8FXI7 LOC8035542 PTHR23189:SF48 RNA RECOGNITION MOTIF-CONTAINING MSX2-INTERACTING PROTEIN mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of RNA splicing#GO:0043484;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120836226|UniProtKB=A0ACM8FUX5 A0ACM8FUX5 LOC120836226 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8042181|UniProtKB=A0ACM8E0X6 A0ACM8E0X6 LOC8042181 PTHR45630:SF23 CATION-TRANSPORTING ATPASE-RELATED CATION-TRANSPORTING ATPASE polyamine transmembrane transporter activity#GO:0015203;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;transmembrane transport#GO:0055085;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;nitrogen compound transport#GO:0071705;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8026196|UniProtKB=A0ACM8FKG3 A0ACM8FKG3 LOC8026196 PTHR45627:SF1 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE TYPE 8 catalytic activity#GO:0003824;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;lyase activity#GO:0016829;adenylate cyclase activity#GO:0004016 carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;signal transduction#GO:0007165;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleotide metabolic process#GO:0006163;regulation of biological process#GO:0050789;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;G protein-coupled receptor signaling pathway#GO:0007186;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;purine ribonucleotide biosynthetic process#GO:0009152 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 adenylate cyclase#PC00043 Endothelin signaling pathway#P00019>Adenylate cyclase#P00569;GABA-B receptor II signaling#P05731>AC#P05760;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>cAMP cyclase#P00719 IXOSC|EnsemblGenome=LOC8036331|UniProtKB=A0ACM8E224 A0ACM8E224 LOC8036331 PTHR21521:SF0 AMUN, ISOFORM A AMUN, ISOFORM A IXOSC|EnsemblGenome=LOC115322475|UniProtKB=A0ACM8F9M7 A0ACM8F9M7 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC121835608|UniProtKB=A0ACM8FW88 A0ACM8FW88 LOC121835608 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC115320756|UniProtKB=A0ACM8EP04 A0ACM8EP04 LOC115320756 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8032326|UniProtKB=A0ACM8E2B1 A0ACM8E2B1 LOC8032326 PTHR11266:SF131 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 FI08002P-RELATED intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115318040|UniProtKB=A0ACM8FM05 A0ACM8FM05 LOC115318040 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833011|UniProtKB=A0ACM8FJZ5 A0ACM8FJZ5 LOC121833011 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 transferase#PC00220 IXOSC|EnsemblGenome=LOC8053423|UniProtKB=A0ACM8E3E9 A0ACM8E3E9 Tango4 PTHR19923:SF0 WD40 REPEAT PROTEINPRL1/PRL2-RELATED PLEIOTROPIC REGULATOR 1 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 spliceosomal complex#GO:0005681;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;Prp19 complex#GO:0000974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8039900|UniProtKB=A0ACM8E655 A0ACM8E655 PTHR16017:SF0 GASTRULATION DEFECTIVE PROTEIN 1-RELATED WD REPEAT-CONTAINING PROTEIN 70 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;site of double-strand break#GO:0035861;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115315068|UniProtKB=A0ACM8EX95 A0ACM8EX95 LOC115315068 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8053012|UniProtKB=A0ACM8DR31 A0ACM8DR31 LOC8053012 PTHR10836:SF76 GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE-RELATED oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;oxidoreductase activity#GO:0016491;glyceraldehyde-3-phosphate dehydrogenase (phosphorylating, [NAD(P)+] ) activity#GO:0043891 phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;pyridine-containing compound catabolic process#GO:0072526;purine-containing compound metabolic process#GO:0072521;ribonucleoside diphosphate metabolic process#GO:0009185;purine nucleotide metabolic process#GO:0006163;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;oxoacid metabolic process#GO:0043436;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;ATP metabolic process#GO:0046034;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;nicotinamide nucleotide metabolic process#GO:0046496;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ADP catabolic process#GO:0046032;purine-containing compound catabolic process#GO:0072523;purine nucleoside diphosphate catabolic process#GO:0009137;nucleobase-containing small molecule metabolic process#GO:0055086;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside diphosphate catabolic process#GO:0009134;purine ribonucleotide catabolic process#GO:0009154;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;nucleoside triphosphate metabolic process#GO:0009141;nucleoside phosphate metabolic process#GO:0006753;carbohydrate metabolic process#GO:0005975;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;cellular respiration#GO:0045333;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;purine ribonucleoside triphosphate metabolic process#GO:0009205;glycolytic process#GO:0006096;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;purine ribonucleoside diphosphate metabolic process#GO:0009179;generation of precursor metabolites and energy#GO:0006091;energy derivation by oxidation of organic compounds#GO:0015980;ADP metabolic process#GO:0046031 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Huntington disease#P00029>GAPDH#P00810;Glycolysis#P00024>Glyceraldehyde 3-phosphate dehydrogenase#P00676 IXOSC|EnsemblGenome=LOC121838187|UniProtKB=A0ACM8G826 A0ACM8G826 LOC121838187 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115329281|UniProtKB=A0ACM8G2D7 A0ACM8G2D7 LOC115329281 PTHR13139:SF54 RING FINGER AND CCCH-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN RING-TYPE E3 UBIQUITIN TRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;binding#GO:0005488;nucleic acid binding#GO:0003676;acyltransferase activity#GO:0016746;mRNA binding#GO:0003729;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;double-stranded RNA binding#GO:0003725;RNA binding#GO:0003723;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;RNA catabolic process#GO:0006401;protein catabolic process#GO:0030163;positive regulation of macromolecule metabolic process#GO:0010604;protein ubiquitination#GO:0016567;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;regulation of mRNA metabolic process#GO:1903311;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein modification process#GO:0036211;positive regulation of mRNA catabolic process#GO:0061014;modification-dependent protein catabolic process#GO:0019941;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-translational protein modification#GO:0043687;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of catabolic process#GO:0009896;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080 IXOSC|EnsemblGenome=LOC8035202|UniProtKB=A0ACM8E2H0 A0ACM8E2H0 Dd PTHR12210:SF70 DULLARD PROTEIN PHOSPHATASE CTD NUCLEAR ENVELOPE PHOSPHATASE 1 hydrolase activity#GO:0016787;phosphoprotein phosphatase activity#GO:0004721;protein serine/threonine phosphatase activity#GO:0004722;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC115310240|UniProtKB=A0ACM8FSI2 A0ACM8FSI2 LOC115310240 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115331031|UniProtKB=A0ACM8EC42 A0ACM8EC42 LOC115331031 PTHR37984:SF30 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039717|UniProtKB=A0ACM8DKG3 A0ACM8DKG3 nsl1 PTHR22443:SF18 NON-SPECIFIC LETHAL 1, ISOFORM M NON-SPECIFIC LETHAL 1, ISOFORM M binding#GO:0005488;enzyme binding#GO:0019899;protein binding#GO:0005515 chromatin#GO:0000785;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;transferase complex#GO:1990234;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;NSL complex#GO:0044545;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120842732|UniProtKB=A0ACM8EUH5 A0ACM8EUH5 LOC120842732 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120842999|UniProtKB=A0ACM8EV10 A0ACM8EV10 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850873|UniProtKB=A0ACM8FBY5 A0ACM8FBY5 LOC120850873 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8028676|UniProtKB=A0ACM8E9Y5 A0ACM8E9Y5 LOC8028676 PTHR22722:SF14 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED MEGALIN, ISOFORM A hormone binding#GO:0042562;binding#GO:0005488 receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987 cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590 IXOSC|EnsemblGenome=LOC115308805|UniProtKB=A0ACM8EZ12 A0ACM8EZ12 LOC115308805 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308518|UniProtKB=A0ACM8ERV8 A0ACM8ERV8 LOC115308518 PTHR11129:SF2 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 transferase complex#GO:1990234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8053706|UniProtKB=A0ACM8E8X6 A0ACM8E8X6 LOC8053706 PTHR24064:SF316 SOLUTE CARRIER FAMILY 22 MEMBER MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8039454|UniProtKB=A0ACM8FQY1 A0ACM8FQY1 LOC8039454 PTHR42752:SF1 IMIDAZOLONEPROPIONASE IMIDAZOLONEPROPIONASE-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8033292|UniProtKB=A0ACM8DHN6 A0ACM8DHN6 LOC8033292 PTHR21398:SF6 AGAP007094-PA SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115327491|UniProtKB=A0ACM8F803 A0ACM8F803 LOC115327491 PTHR22950:SF646 AMINO ACID TRANSPORTER SOLUTE CARRIER FAMILY 38 MEMBER 10 L-amino acid transmembrane transporter activity#GO:0015179;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 IXOSC|EnsemblGenome=LOC120846160|UniProtKB=A0ACM8F2L3 A0ACM8F2L3 LOC120846160 PTHR24223:SF485 ATP-BINDING CASSETTE SUB-FAMILY C ABC-TYPE GLUTATHIONE-S-CONJUGATE TRANSPORTER localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8023627|UniProtKB=A0ACM8DYT2 A0ACM8DYT2 LOC8023627 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC120837904|UniProtKB=A0ACM8EII7 A0ACM8EII7 LOC120837904 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8034986|UniProtKB=A0ACM8FUJ5 A0ACM8FUJ5 LOC8034986 PTHR45656:SF4 PROTEIN CBR-CLEC-78 COMPLEMENT COMPONENT RECEPTOR 1-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120838972|UniProtKB=A0ACM8ELS5 A0ACM8ELS5 LOC120838972 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8028046|UniProtKB=A0ACM8EKQ2 A0ACM8EKQ2 LOC8028046 PTHR46356:SF1 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC115321683|UniProtKB=A0ACM8E1Y6 A0ACM8E1Y6 LOC115321683 PTHR22227:SF6 FAMILY WITH SEQUENCE SIMILARITY 122B ISOFORM X1 PROTEIN FAM122B ISOFORM X1 molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;protein phosphatase inhibitor activity#GO:0004864;protein phosphatase regulator activity#GO:0019888;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;protein serine/threonine phosphatase inhibitor activity#GO:0004865 regulation of proteasomal protein catabolic process#GO:0061136;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436;biological regulation#GO:0065007;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of proteasomal protein catabolic process#GO:1901800;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of biological process#GO:0050789;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;positive regulation of metabolic process#GO:0009893;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of protein metabolic process#GO:0051247 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC121835792|UniProtKB=A0ACM8FWY6 A0ACM8FWY6 LOC121835792 PTHR12429:SF6 NEURALIZED PROTEIN NEURALIZED ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824 regulation of Notch signaling pathway#GO:0008593;regulation of signaling#GO:0023051;protein transport#GO:0015031;localization#GO:0051179;regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;transport#GO:0006810;regulation of response to stimulus#GO:0048583;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;import into cell#GO:0098657;establishment of protein localization to organelle#GO:0072594;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115321133|UniProtKB=A0ACM8F1W7 A0ACM8F1W7 LOC115321133 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC121833753|UniProtKB=A0ACM8FMS0 A0ACM8FMS0 LOC121833753 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8034106|UniProtKB=A0ACM8DMW1 A0ACM8DMW1 LOC8034106 PTHR16470:SF0 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 UBIQUITIN DOMAIN-CONTAINING PROTEIN UBFD1 IXOSC|EnsemblGenome=LOC8035248|UniProtKB=A0ACM8FP18 A0ACM8FP18 PTHR18966:SF411 IONOTROPIC GLUTAMATE RECEPTOR IONOTROPIC RECEPTOR 25A transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;glutamate receptor activity#GO:0008066;transmembrane transporter activity#GO:0022857;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315 biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268 postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;synapse#GO:0045202;cellular anatomical structure#GO:0110165;asymmetric synapse#GO:0032279;organelle#GO:0043226;synaptic membrane#GO:0097060;cell junction#GO:0030054;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115330843|UniProtKB=A0ACM8EBL7 A0ACM8EBL7 LOC115330843 PTHR11662:SF465 SOLUTE CARRIER FAMILY 17 SIALIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8023884|UniProtKB=A0ACM8DHQ2 A0ACM8DHQ2 fl(2)d PTHR15217:SF0 WILMS' TUMOR 1-ASSOCIATING PROTEIN PRE-MRNA-SPLICING REGULATOR WTAP enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774;regulation of RNA metabolic process#GO:0051252;mRNA processing#GO:0006397;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of alternative mRNA splicing, via spliceosome#GO:0000381 intracellular membrane-bounded organelle#GO:0043231;methyltransferase complex#GO:0034708;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121835353|UniProtKB=A0ACM8FTN1 A0ACM8FTN1 LOC121835353 PTHR15228:SF37 SPERMATHECAL PHYSIOLOGY VARIANT F-BAR DOMAIN-CONTAINING PROTEIN enzyme activator activity#GO:0008047;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;regulation of small GTPase mediated signal transduction#GO:0051056;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523 GTPase-activating protein#PC00257;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120841369|UniProtKB=A0ACM8ERM4 A0ACM8ERM4 LOC120841369 PTHR47980:SF23 LD44762P SMALL MONOMERIC GTPASE intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;exocytosis#GO:0006887;endosomal transport#GO:0016197;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;localization within membrane#GO:0051668;secretion#GO:0046903;cellular localization#GO:0051641;localization#GO:0051179;secretion by cell#GO:0032940;endocytic recycling#GO:0032456;export from cell#GO:0140352 endomembrane system#GO:0012505;cytoplasm#GO:0005737;secretory vesicle#GO:0099503;membrane#GO:0016020;recycling endosome#GO:0055037;Golgi apparatus#GO:0005794;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 TGF-beta signaling pathway#P00052>Ras-GTP#P01280;TGF-beta signaling pathway#P00052>Ras-GDP#P01291 IXOSC|EnsemblGenome=LOC8028503|UniProtKB=A0ACM8DGJ7 A0ACM8DGJ7 LOC8028503 PTHR11452:SF95 ALPHA-GALACTOSIDASE/ALPHA-N-ACETYLGALACTOSAMINIDASE ALPHA-GALACTOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 oligosaccharide metabolic process#GO:0009311;metabolic process#GO:0008152;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;carbohydrate derivative catabolic process#GO:1901136;glycosyl compound catabolic process#GO:1901658;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120850324|UniProtKB=A0ACM8F8J4 A0ACM8F8J4 LOC120850324 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=ISCI019144|UniProtKB=B7PP17 B7PP17 ISCW019144 PTHR13273:SF14 ANAMORSIN ANAMORSIN cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120842103|UniProtKB=A0ACM8ET24 A0ACM8ET24 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121833159|UniProtKB=A0ACM8FIF6 A0ACM8FIF6 LOC121833159 PTHR35555:SF4 ENDONUCLEASE-REVERSE TRANSCRIPTASE TRANSMEMBRANE PROTEIN IXOSC|EnsemblGenome=LOC8043197|UniProtKB=A0ACM8ED46 A0ACM8ED46 LOC8043197 PTHR43963:SF4 CARBONYL REDUCTASE 1-RELATED CARBONYL REDUCTASE (NADPH) oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8025112|UniProtKB=A0ACM8DUD3 A0ACM8DUD3 Trmt6 PTHR12945:SF0 TRANSLATION INITIATION FACTOR EIF3-RELATED TRNA (ADENINE(58)-N(1))-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT TRM6 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;methyltransferase complex#GO:0034708;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494 translation initiation factor#PC00224 IXOSC|EnsemblGenome=LOC8041770|UniProtKB=A0ACM8E1S0 A0ACM8E1S0 LOC8041770 PTHR20855:SF15 ADIPOR/PROGESTIN RECEPTOR-RELATED PROGESTIN AND ADIPOQ RECEPTOR FAMILY MEMBER 3 molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 macromolecule localization#GO:0033036;protein localization to Golgi apparatus#GO:0034067;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115316090|UniProtKB=A0ACM8DW50 A0ACM8DW50 slbo PTHR23334:SF75 CCAAT/ENHANCER BINDING PROTEIN CCAAT_ENHANCER-BINDING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC121838400|UniProtKB=A0ACM8G8Y8 A0ACM8G8Y8 LOC121838400 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115312855|UniProtKB=A0ACM8EK85 A0ACM8EK85 LOC115312855 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050860|UniProtKB=A0ACM8FTD1 A0ACM8FTD1 LOC8050860 PTHR43730:SF1 BETA-MANNOSIDASE BETA-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;protein catabolic process#GO:0030163;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120851079|UniProtKB=A0ACM8FW87 A0ACM8FW87 LOC120851079 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC121833506|UniProtKB=A0ACM8FMB2 A0ACM8FMB2 LOC121833506 PTHR42760:SF133 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER 3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8032199|UniProtKB=A0ACM8FRW8 A0ACM8FRW8 LOC8032199 PTHR15565:SF0 AATF PROTEIN APOPTOSIS ANTAGONIZING TRANSCRIPTION FACTOR PROTEIN AATF gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120839752|UniProtKB=A0ACM8EMR3 A0ACM8EMR3 LOC120839752 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8026123|UniProtKB=A0ACM8E064 A0ACM8E064 LOC8026123 PTHR10174:SF166 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED LD40136P phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121837353|UniProtKB=A0ACM8G4L0 A0ACM8G4L0 LOC121837353 PTHR24251:SF55 OVOCHYMASE-RELATED SCAVENGER RECEPTOR CYSTEINE-RICH DOMAIN-CONTAINING PROTEIN DMBT1 ISOFORM X1 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8042850|UniProtKB=A0ACM8F311 A0ACM8F311 LOC8042850 PTHR10745:SF0 GLYCYL-TRNA SYNTHETASE/DNA POLYMERASE SUBUNIT GAMMA-2 GLYCINE--TRNA LIGASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8052957|UniProtKB=A0ACM8DUE4 A0ACM8DUE4 LOC8052957 PTHR46209:SF3 PX DOMAIN-CONTAINING PROTEIN PX DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;phosphatidylinositol phosphate binding#GO:1901981;phospholipid binding#GO:0005543;binding#GO:0005488 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 IXOSC|EnsemblGenome=LOC8034751|UniProtKB=A0ACM8E5P4 A0ACM8E5P4 LOC8034751 PTHR12447:SF31 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 13 LD31969P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 biological regulation#GO:0065007;regulation of receptor-mediated endocytosis#GO:0048259;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;regulation of vesicle-mediated transport#GO:0060627;regulation of biological process#GO:0050789;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of endocytosis#GO:0030100 plasma membrane#GO:0005886;cytoplasm#GO:0005737;endomembrane system#GO:0012505;late endosome#GO:0005770;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121834094|UniProtKB=A0ACM8FQ46 A0ACM8FQ46 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838272|UniProtKB=A0ACM8G743 A0ACM8G743 LOC121838272 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8041652|UniProtKB=A0ACM8DTN2 A0ACM8DTN2 RpL7A PTHR23105:SF1 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER LARGE RIBOSOMAL SUBUNIT PROTEIN EL8 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of LSU-rRNA#GO:0000470;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115332205|UniProtKB=A0ACM8EDF9 A0ACM8EDF9 LOC115332205 PTHR20913:SF7 TBC1 DOMAIN FAMILY MEMBER 20/GTPASE RE60063P enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme regulator activity#GO:0030234 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular component organization#GO:0016043;organelle organization#GO:0006996;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;establishment of localization#GO:0051234;cellular localization#GO:0051641;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8030704|UniProtKB=A0ACM8EGF7 A0ACM8EGF7 GCC88 PTHR23157:SF25 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115309144|UniProtKB=A0ACM8F1H1 A0ACM8F1H1 LOC115309144 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8032695|UniProtKB=A0ACM8DGI4 A0ACM8DGI4 PTHR11117:SF2 SUCCINYL-COA LIGASE SUBUNIT ALPHA SUCCINATE--COA LIGASE [ADP_GDP-FORMING] SUBUNIT ALPHA, MITOCHONDRIAL ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 aerobic respiration#GO:0009060;cellular respiration#GO:0045333;energy derivation by oxidation of organic compounds#GO:0015980;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;cellular process#GO:0009987;tricarboxylic acid cycle#GO:0006099;primary metabolic process#GO:0044238 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;ligase#PC00142 TCA cycle#P00051>Succinyl CoA Synthetase#P01274 IXOSC|EnsemblGenome=LOC8044076|UniProtKB=A0ACM8DL76 A0ACM8DL76 LOC8044076 PTHR15375:SF26 ACTIVATOR OF S-PHASE KINASE-RELATED PROTEIN CHIFFON kinase modulator#PC00140;kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8041551|UniProtKB=A0ACM8EKN1 A0ACM8EKN1 LOC8041551 PTHR14217:SF1 INOSITOL-TETRAKISPHOSPHATE 1-KINASE INOSITOL-TETRAKISPHOSPHATE 1-KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137 IXOSC|EnsemblGenome=LOC120841882|UniProtKB=A0ACM8ETP9 A0ACM8ETP9 LOC120841882 PTHR15955:SF8 RWD DOMAIN CONTAINING PROTEIN 2 RWD DOMAIN-CONTAINING PROTEIN 2B ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8026416|UniProtKB=A0ACM8DHQ8 A0ACM8DHQ8 Sap30 PTHR13286:SF6 SAP30 HISTONE DEACETYLASE COMPLEX SUBUNIT SAP30L transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8023112|UniProtKB=A0ACM8DGF7 A0ACM8DGF7 LOC8023112 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120846493|UniProtKB=A0ACM8G2P9 A0ACM8G2P9 LOC120846493 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115329803|UniProtKB=A0ACM8FBX2 A0ACM8FBX2 LOC115329803 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115309649|UniProtKB=A0ACM8DP26 A0ACM8DP26 LOC115309649 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8028812|UniProtKB=A0ACM8FLL7 A0ACM8FLL7 LOC8028812 PTHR23339:SF109 TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE TYR_PHOSPHATASE_2 DOMAIN-CONTAINING PROTEIN hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115329597|UniProtKB=A0ACM8EAS3 A0ACM8EAS3 LOC115329597 PTHR23235:SF182 KRUEPPEL-LIKE TRANSCRIPTION FACTOR KRUEPPEL-LIKE FACTOR 2 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120835975|UniProtKB=A0ACM8G0D3 A0ACM8G0D3 LOC120835975 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050519|UniProtKB=A0ACM8FW28 A0ACM8FW28 LOC8050519 PTHR24166:SF67 ROLLING PEBBLES, ISOFORM B ANKYRIN REPEAT PROTEIN 1 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8035315|UniProtKB=A0ACM8DXZ8 A0ACM8DXZ8 LOC8035315 PTHR22870:SF335 REGULATOR OF CHROMOSOME CONDENSATION RCC1 AND BTB DOMAIN CONTAINING PROTEIN 2 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8037218|UniProtKB=A0ACM8EAJ9 A0ACM8EAJ9 LOC8037218 PTHR10736:SF70 BESTROPHIN BESTROPHIN HOMOLOG passive transmembrane transporter activity#GO:0022803;chloride transmembrane transporter activity#GO:0015108;chloride channel activity#GO:0005254;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic anion transmembrane transporter activity#GO:0008509;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic anion channel activity#GO:0005253;channel activity#GO:0015267 transport#GO:0006810;chloride transport#GO:0006821;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;chloride transmembrane transport#GO:1902476;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;monoatomic anion transport#GO:0006820;monoatomic ion transmembrane transport#GO:0034220;monoatomic anion transmembrane transport#GO:0098656 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC121835738|UniProtKB=A0ACM8FWQ3 A0ACM8FWQ3 LOC121835738 PTHR33198:SF22 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332842|UniProtKB=A0ACM8EDQ5 A0ACM8EDQ5 LOC115332842 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120838067|UniProtKB=A0ACM8EJ38 A0ACM8EJ38 LOC120838067 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8028603|UniProtKB=A0ACM8E0P5 A0ACM8E0P5 LOC8028603 PTHR11878:SF76 SODIUM/CALCIUM EXCHANGER CALX-BETA DOMAIN-CONTAINING PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075 monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;establishment of localization#GO:0051234;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;homeostatic process#GO:0042592;export from cell#GO:0140352;metal ion transport#GO:0030001;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8023482|UniProtKB=A0ACM8DPP1 A0ACM8DPP1 LOC8023482 PTHR16515:SF85 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8039848|UniProtKB=A0ACM8E0Z7 A0ACM8E0Z7 LOC8039848 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;monoatomic ion homeostasis#GO:0050801;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC115332568|UniProtKB=A0ACM8FYX2 A0ACM8FYX2 LOC115332568 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834264|UniProtKB=A0ACM8FPD3 A0ACM8FPD3 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120846315|UniProtKB=A0ACM8F211 A0ACM8F211 LOC120846315 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120841583|UniProtKB=A0ACM8FIK2 A0ACM8FIK2 LOC120841583 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC8037325|UniProtKB=A0ACM8FND4 A0ACM8FND4 PTHR12932:SF9 P25 ALPHA-RELATED TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488 positive regulation of cellular component biogenesis#GO:0044089;positive regulation of protein polymerization#GO:0032273;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;microtubule polymerization#GO:0046785;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of protein polymerization#GO:0032271;regulation of cellular component biogenesis#GO:0044087;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;protein polymerization#GO:0051258;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;microtubule bundle formation#GO:0001578;positive regulation of cellular component organization#GO:0051130 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;cellular anatomical structure#GO:0110165;organelle#GO:0043226;supramolecular complex#GO:0099080 non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC8051660|UniProtKB=A0ACM8ET72 A0ACM8ET72 LOC8051660 PTHR10751:SF144 GUANYLATE BINDING PROTEIN GUANYLATE-BINDING PROTEIN ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924 G-protein#PC00020;heterotrimeric G-protein#PC00117 IXOSC|EnsemblGenome=LOC120844203|UniProtKB=A0ACM8EY69 A0ACM8EY69 LOC120844203 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024088|UniProtKB=A0ACM8DHY4 A0ACM8DHY4 Sec22 PTHR45837:SF3 VESICLE-TRAFFICKING PROTEIN SEC22B VESICLE-TRAFFICKING PROTEIN SEC22B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;SNAP receptor activity#GO:0005484 endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;Golgi organization#GO:0007030;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;vesicle organization#GO:0016050;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;organelle organization#GO:0006996;membrane fusion#GO:0061025;organelle membrane fusion#GO:0090174;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284 vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;ER to Golgi transport vesicle membrane#GO:0012507;Golgi apparatus#GO:0005794;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;SNARE complex#GO:0031201;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;COPII-coated ER to Golgi transport vesicle#GO:0030134;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endoplasmic reticulum#GO:0005783;Golgi membrane#GO:0000139;bounding membrane of organelle#GO:0098588;intracellular vesicle#GO:0097708;coated vesicle membrane#GO:0030662;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135 IXOSC|EnsemblGenome=LOC8034009|UniProtKB=A0ACM8EAJ1 A0ACM8EAJ1 Esyt2 PTHR45761:SF1 EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C EXTENDED SYNAPTOTAGMIN-LIKE PROTEIN 2, ISOFORM C phosphatidylinositol binding#GO:0035091;phospholipid binding#GO:0005543;phosphatidylcholine binding#GO:0031210;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169;lipid binding#GO:0008289 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC120842953|UniProtKB=A0ACM8EUZ4 A0ACM8EUZ4 LOC120842953 PTHR10322:SF23 DNA POLYMERASE CATALYTIC SUBUNIT DNA POLYMERASE DELTA CATALYTIC SUBUNIT DNA-directed DNA polymerase activity#GO:0003887;hydrolase activity#GO:0016787;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;exonuclease activity#GO:0004527;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;DNA exonuclease activity#GO:0004529;transferase activity#GO:0016740;3'-5' exonuclease activity#GO:0008408;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097 nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base-excision repair#GO:0006284;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;protein-DNA complex#GO:0032993;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;replisome#GO:0030894;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;DNA polymerase complex#GO:0042575;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634 DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 IXOSC|EnsemblGenome=LOC121833285|UniProtKB=A0ACM8FIV4 A0ACM8FIV4 LOC121833285 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120848422|UniProtKB=A0ACM8F6N2 A0ACM8F6N2 LOC120848422 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8025570|UniProtKB=A0ACM8FR59 A0ACM8FR59 LOC8025570 PTHR23113:SF376 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAS GUANINE NUCLEOTIDE EXCHANGE FACTOR C guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;Ras protein signal transduction#GO:0007265;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC115312873|UniProtKB=A0ACM8EU52 A0ACM8EU52 LOC115312873 PTHR19865:SF0 U3 SMALL NUCLEOLAR RNA INTERACTING PROTEIN 2 U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 RNA binding#GO:0003723;U3 snoRNA binding#GO:0034511;nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254 small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC115328903|UniProtKB=A0ACM8FEK9 A0ACM8FEK9 LOC115328903 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115323664|UniProtKB=A0ACM8FG08 A0ACM8FG08 holn1 PTHR13138:SF3 PROTEIN LIN1 CD2 ANTIGEN CYTOPLASMIC TAIL-BINDING PROTEIN 2 mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;protein-containing complex organization#GO:0043933;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;mRNA splicing, via spliceosome#GO:0000398;protein-containing complex assembly#GO:0065003;spliceosomal snRNP assembly#GO:0000387;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;U5 snRNP#GO:0005682;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC115316581|UniProtKB=A0ACM8DWH7 A0ACM8DWH7 LOC115316581 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115325326|UniProtKB=A0ACM8F7D6 A0ACM8F7D6 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120850791|UniProtKB=A0ACM8FAX7 A0ACM8FAX7 LOC120850791 PTHR21974:SF2 RE15880P RE15880P cilium#GO:0005929;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115310973|UniProtKB=A0ACM8EPP9 A0ACM8EPP9 LOC115310973 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051337|UniProtKB=A0ACM8FF48 A0ACM8FF48 LOC8051337 PTHR15860:SF0 UNCHARACTERIZED RING FINGER-CONTAINING PROTEIN LP20373P catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 IXOSC|EnsemblGenome=LOC8035099|UniProtKB=A0ACM8E6Q6 A0ACM8E6Q6 LOC8035099 PTHR43448:SF2 PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659 biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014;cellular process#GO:0009987;heme biosynthetic process#GO:0006783;pigment metabolic process#GO:0042440;porphyrin-containing compound biosynthetic process#GO:0006779;porphyrin-containing compound metabolic process#GO:0006778;pigment biosynthetic process#GO:0046148;metabolic process#GO:0008152;tetrapyrrole metabolic process#GO:0033013 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 acyltransferase#PC00042;transferase#PC00220;metabolite interconversion enzyme#PC00262 Heme biosynthesis#P02746>Protoheme IX farnesyl transferase#P02982 IXOSC|EnsemblGenome=LOC8028397|UniProtKB=A0ACM8EQ72 A0ACM8EQ72 LOC8028397 PTHR34008:SF2 REPETITIVE PROLINE-RICH CELL WALL PROTEIN 1 REPETITIVE PROLINE-RICH CELL WALL PROTEIN 1 IXOSC|EnsemblGenome=LOC120845939|UniProtKB=A0ACM8F140 A0ACM8F140 LOC120845939 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8053619|UniProtKB=A0ACM8DM42 A0ACM8DM42 RpL13A PTHR11545:SF3 RIBOSOMAL PROTEIN L13 LARGE RIBOSOMAL SUBUNIT PROTEIN UL13 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of translation#GO:0006417;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of translation#GO:0017148 ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120837193|UniProtKB=A0ACM8EHT6 A0ACM8EHT6 LOC120837193 PTHR23428:SF386 HISTONE H2B HISTONE H2B 1-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115332159|UniProtKB=A0ACM8FJA7 A0ACM8FJA7 LOC115332159 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115322427|UniProtKB=A0ACM8E398 A0ACM8E398 LOC115322427 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115319327|UniProtKB=A0ACM8DZQ6 A0ACM8DZQ6 LOC115319327 PTHR10083:SF390 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED PAPILIN endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8024858|UniProtKB=A0ACM8FTF3 A0ACM8FTF3 LOC8024858 PTHR13723:SF275 ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE STALL, ISOFORM C endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;extracellular matrix organization#GO:0030198;protein metabolic process#GO:0019538;cellular process#GO:0009987;cellular component organization#GO:0016043;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8043787|UniProtKB=A0ACM8DGZ1 A0ACM8DGZ1 LOC8043787 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC120848170|UniProtKB=A0ACM8F5C0 A0ACM8F5C0 LOC120848170 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8023303|UniProtKB=A0ACM8FBA9 A0ACM8FBA9 LOC8023303 PTHR11552:SF233 GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE FI02019P oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8043029|UniProtKB=A0ACM8FAT0 A0ACM8FAT0 LOC8043029 PTHR24384:SF189 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8023892|UniProtKB=A0ACM8DHP9 A0ACM8DHP9 LOC8023892 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120845837|UniProtKB=A0ACM8F0P2 A0ACM8F0P2 LOC120845837 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039455|UniProtKB=A0ACM8FD82 A0ACM8FD82 LOC8039455 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8030423|UniProtKB=A0ACM8G6A3 A0ACM8G6A3 LOC8030423 PTHR12620:SF4 U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT ZINC FINGER (CCCH TYPE), RNA-BINDING MOTIF AND SERINE_ARGININE RICH 2 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;pre-mRNA binding#GO:0036002 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8038112|UniProtKB=A0ACM8EC22 A0ACM8EC22 LOC8038112 PTHR24338:SF0 HOMEOBOX PROTEIN MSX MUSCLE SEGMENTATION HOMEOBOX transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;embryo development#GO:0009790;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of gene expression#GO:0010468;embryonic morphogenesis#GO:0048598;multicellular organism development#GO:0007275;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC121838131|UniProtKB=A0ACM8G6W8 A0ACM8G6W8 LOC121838131 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838406|UniProtKB=A0ACM8ELB9 A0ACM8ELB9 LOC8024030 PTHR11043:SF0 ZETA-COAT PROTEIN COATOMER SUBUNIT ZETA establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;vesicle-mediated transport#GO:0016192;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;intra-Golgi vesicle-mediated transport#GO:0006891 vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;coated membrane#GO:0048475;membrane coat#GO:0030117;vesicle membrane#GO:0012506;membrane#GO:0016020;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 vesicle coat protein#PC00235;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115308854|UniProtKB=A0ACM8FAR9 A0ACM8FAR9 LOC115308854 PTHR47978:SF66 FAMILY NOT NAMED RAB, MEMBER OF RAS ONCO FAMILY-LIKE 2A ion binding#GO:0043167;GTPase activity#GO:0003924;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8043178|UniProtKB=A0ACM8G196 A0ACM8G196 LOC8043178 PTHR11347:SF20 CYCLIC NUCLEOTIDE PHOSPHODIESTERASE PHOSPHODIESTERASE cyclic-nucleotide phosphodiesterase activity#GO:0004112;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of cellular process#GO:0048523;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;negative regulation of response to stimulus#GO:0048585 phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8034720|UniProtKB=A0ACM8DYH3 A0ACM8DYH3 Ssrp PTHR45849:SF7 FACT COMPLEX SUBUNIT SSRP1 FACT COMPLEX SUBUNIT SSRP1 histone binding#GO:0042393;chromatin binding#GO:0003682;binding#GO:0005488;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of chromatin organization#GO:1902275 chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;chromosome#GO:0005694;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC121046123|UniProtKB=A0ACM8FE69 A0ACM8FE69 LOC121046123 PTHR19303:SF82 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115310103|UniProtKB=A0ACM8DPH0 A0ACM8DPH0 LOC115310103 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115326704|UniProtKB=A0ACM8E692 A0ACM8E692 Cdk9 PTHR24056:SF233 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 9 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;cyclin-dependent protein kinase activity#GO:0097472;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein serine/threonine kinase activity#GO:0004693 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;transcription elongation by RNA polymerase II#GO:0006368;gene expression#GO:0010467;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121837120|UniProtKB=A0ACM8G399 A0ACM8G399 LOC121837120 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8023556|UniProtKB=A0ACM8DH88 A0ACM8DH88 LOC8023556 PTHR46041:SF2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 MITOCHONDRIAL INNER MEMBRANE PROTEASE SUBUNIT 2 peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 protein localization to mitochondrion#GO:0070585;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;protein localization to organelle#GO:0033365;localization#GO:0051179 organelle membrane#GO:0031090;endopeptidase complex#GO:1905369;inner mitochondrial membrane protein complex#GO:0098800;peptidase complex#GO:1905368;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane protein complex#GO:0098796;organelle envelope#GO:0031967 protease#PC00190 IXOSC|EnsemblGenome=LOC120847785|UniProtKB=A0ACM8F4U6 A0ACM8F4U6 LOC120847785 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8025091|UniProtKB=A0ACM8E646 A0ACM8E646 LOC8025091 PTHR23067:SF14 DOUBLE-STRANDED RNA-BINDING ZINC FINGER PROTEIN SUBFAMILY NOT NAMED nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8036252|UniProtKB=A0ACM8E8N2 A0ACM8E8N2 LOC8036252 PTHR15933:SF20 PROTEIN CBG16327 F-BOX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040103|UniProtKB=A0ACM8DKI6 A0ACM8DKI6 LOC8040103 PTHR48438:SF3 ALPHA-(1,3)-FUCOSYLTRANSFERASE C-RELATED FUCOSYLTRANSFERASE IXOSC|EnsemblGenome=LOC8039620|UniProtKB=A0ACM8G857 A0ACM8G857 LOC8039620 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC120849915|UniProtKB=A0ACM8F9L9 A0ACM8F9L9 LOC120849915 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8038184|UniProtKB=A0ACM8DGN6 A0ACM8DGN6 LOC8038184 PTHR45985:SF6 FAMILY NOT NAMED FI03450P IXOSC|EnsemblGenome=LOC120839933|UniProtKB=A0ACM8ENZ9 A0ACM8ENZ9 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121837179|UniProtKB=A0ACM8G2N3 A0ACM8G2N3 LOC121837179 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033322|UniProtKB=A0ACM8EJ27 A0ACM8EJ27 LOC8033322 PTHR10131:SF138 TNF RECEPTOR ASSOCIATED FACTOR TNF RECEPTOR-ASSOCIATED FACTOR 3_5 RING DOMAIN-CONTAINING PROTEIN protein-macromolecule adaptor activity#GO:0030674;cytokine receptor binding#GO:0005126;signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515;signaling adaptor activity#GO:0035591;molecular adaptor activity#GO:0060090;tumor necrosis factor receptor superfamily binding#GO:0032813 signal transduction#GO:0007165;cellular process#GO:0009987;regulation of canonical NF-kappaB signal transduction#GO:0043122;response to tumor necrosis factor#GO:0034612;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;response to cytokine#GO:0034097;response to chemical#GO:0042221;regulation of response to stimulus#GO:0048583;cell surface receptor signaling pathway#GO:0007166;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;cellular response to stimulus#GO:0051716;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;cytokine-mediated signaling pathway#GO:0019221;regulation of intracellular signal transduction#GO:1902531;response to peptide#GO:1901652;cell communication#GO:0007154;tumor necrosis factor-mediated signaling pathway#GO:0033209 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8051441|UniProtKB=A0ACM8DNS0 A0ACM8DNS0 Orc2 PTHR14052:SF0 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 ORIGIN RECOGNITION COMPLEX SUBUNIT 2 DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;DNA replication origin binding#GO:0003688;binding#GO:0005488;nucleic acid binding#GO:0003676 macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;DNA replication initiation#GO:0006270;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;DNA replication#GO:0006260;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;origin recognition complex#GO:0000808;nuclear protein-containing complex#GO:0140513;heterochromatin#GO:0000792;membraneless organelle#GO:0043228;nuclear origin of replication recognition complex#GO:0005664 replication origin binding protein#PC00199 IXOSC|EnsemblGenome=LOC8030797|UniProtKB=A0ACM8DHI2 A0ACM8DHI2 LOC8030797 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8053553|UniProtKB=A0ACM8DL91 A0ACM8DL91 LOC8053553 PTHR11711:SF21 ADP RIBOSYLATION FACTOR-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 6 guanyl nucleotide binding#GO:0019001;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 cellular component organization#GO:0016043;cilium assembly#GO:0060271;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;organelle assembly#GO:0070925;protein transport#GO:0015031;cilium organization#GO:0044782;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;ciliary plasm#GO:0097014;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;cytoplasm#GO:0005737;plasma membrane bounded cell projection#GO:0120025;membraneless organelle#GO:0043228;axoneme#GO:0005930;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;cilium#GO:0005929;intracellular organelle#GO:0043229 G-protein#PC00020 IXOSC|EnsemblGenome=LOC8038296|UniProtKB=A0ACM8E8F0 A0ACM8E8F0 LOC8038296 PTHR10851:SF0 PYRIDOXINE-5-PHOSPHATE OXIDASE PYRIDOXINE-5'-PHOSPHATE OXIDASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;aldehyde metabolic process#GO:0006081;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;pyridine-containing compound metabolic process#GO:0072524;organophosphate biosynthetic process#GO:0090407 mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 oxidase#PC00175;oxidoreductase#PC00176 Vitamin B6 metabolism#P02787>Pyridoxamine phosphate oxidase#P03236;Pyridoxal phosphate salvage pathway#P02770>Pyridoxamine-5-phosphate oxidase#P03120;Pyridoxal phosphate salvage pathway#P02770>Pyridoxine-5-phosphate oxidase#P03123;Pyridoxal-5-phosphate biosynthesis#P02759>Pyridoxine-5-phosphate oxidase#P03061 IXOSC|EnsemblGenome=LOC8035886|UniProtKB=A0ACM8FL81 A0ACM8FL81 shaker PTHR11537:SF113 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAKER metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267 monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;metal ion transport#GO:0030001;action potential#GO:0001508;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transport#GO:0006813;cellular process#GO:0009987 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076 ion channel#PC00133;voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC120838764|UniProtKB=A0ACM8EJW8 A0ACM8EJW8 LOC120838764 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8037289|UniProtKB=A0ACM8DK01 A0ACM8DK01 Polr1C PTHR11800:SF13 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;transferase complex, transferring phosphorus-containing groups#GO:0061695;RNA polymerase I complex#GO:0005736;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;RNA polymerase III complex#GO:0005666;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC120837406|UniProtKB=A0ACM8EHD9 A0ACM8EHD9 LOC120837406 PTHR47772:SF17 ZINC FINGER PROTEIN 200 C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835850|UniProtKB=A0ACM8FW21 A0ACM8FW21 LOC121835850 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8027543|UniProtKB=A0ACM8DWZ3 A0ACM8DWZ3 LOC8027543 PTHR47537:SF2 CUBILIN SOL1, ISOFORM C cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120835931|UniProtKB=A0ACM8F2X8 A0ACM8F2X8 LOC120835931 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;transferase activity#GO:0016740;catalytic activity#GO:0003824 transferase#PC00220;methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120848115|UniProtKB=A0ACM8F666 A0ACM8F666 LOC120848115 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121048423|UniProtKB=A0ACM8FJA9 A0ACM8FJA9 LOC121048423 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317393|UniProtKB=A0ACM8DXH0 A0ACM8DXH0 LOC115317393 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 microbody#GO:0042579;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;peroxisome#GO:0005777;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120844856|UniProtKB=A0ACM8EZR7 A0ACM8EZR7 LOC120844856 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 transferase#PC00220 IXOSC|EnsemblGenome=LOC8035762|UniProtKB=A0ACM8E5Y4 A0ACM8E5Y4 LOC8035762 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121837079|UniProtKB=A0ACM8G209 A0ACM8G209 LOC121837079 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115325687|UniProtKB=A0ACM8G1Z2 A0ACM8G1Z2 LOC115325687 PTHR10127:SF780 DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING METALLOENDOPEPTIDASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120843307|UniProtKB=A0ACM8EWX4 A0ACM8EWX4 LOC120843307 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8050490|UniProtKB=A0ACM8DTN1 A0ACM8DTN1 LOC8050490 PTHR13593:SF103 FAMILY NOT NAMED PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C X DOMAIN CONTAINING, ISOFORM A hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 IXOSC|EnsemblGenome=LOC8025382|UniProtKB=A0ACM8E7B7 A0ACM8E7B7 LOC8025382 PTHR14647:SF87 GALACTOSE-3-O-SULFOTRANSFERASE GALACTOSYLCERAMIDE SULFOTRANSFERASE-LIKE transferase#PC00220 IXOSC|EnsemblGenome=LOC8043472|UniProtKB=A0ACM8F5E7 A0ACM8F5E7 LOC8043472 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824 metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;carnitine metabolic process#GO:0009437;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;microbody#GO:0042579 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC8050674|UniProtKB=A0ACM8ECL0 A0ACM8ECL0 LOC8050674 PTHR19211:SF14 ATP-BINDING TRANSPORT PROTEIN-RELATED ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 1 nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ATP binding#GO:0005524;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC115325102|UniProtKB=A0ACM8E4L7 A0ACM8E4L7 LOC115325102 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583;regulation of immune system process#GO:0002682;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115331407|UniProtKB=A0ACM8F6Z4 A0ACM8F6Z4 PTHR24416:SF655 TYROSINE-PROTEIN KINASE RECEPTOR FIBROBLAST GROWTH FACTOR RECEPTOR HOMOLOG 1 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115322519|UniProtKB=A0ACM8E245 A0ACM8E245 LOC115322519 PTHR16276:SF1 PENTATRICOPEPTIDE REPEAT DOMAIN-CONTAINING PROTEIN 3 SMALL RIBOSOMAL SUBUNIT PROTEIN MS39 binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021 biosynthetic process#GO:0009058;gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120844452|UniProtKB=A0ACM8EYF1 A0ACM8EYF1 LOC120844452 PTHR45749:SF35 ZINC FINGER MYM-TYPE PROTEIN 1 AC-LIKE TRANSPOSASE-RELATED IXOSC|EnsemblGenome=LOC8042478|UniProtKB=A0ACM8E6T8 A0ACM8E6T8 LOC8042478 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC120836273|UniProtKB=A0ACM8EZ24 A0ACM8EZ24 LOC120836273 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8027318|UniProtKB=A0ACM8DIW1 A0ACM8DIW1 LOC8027318 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8040137|UniProtKB=A0ACM8DYE9 A0ACM8DYE9 DCTN6-p27 PTHR13072:SF0 DYNACTIN 6 DYNACTIN SUBUNIT 6 binding#GO:0005488;protein-containing complex binding#GO:0044877 cell cycle#GO:0007049;organelle organization#GO:0006996;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;cellular process#GO:0009987;cell cycle process#GO:0022402;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cytoskeleton organization#GO:0007010;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;actin cytoskeleton#GO:0015629;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226 microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC8053039|UniProtKB=A0ACM8DQ56 A0ACM8DQ56 LOC8053039 PTHR24416:SF645 TYROSINE-PROTEIN KINASE RECEPTOR PDGF- AND VEGF-RECEPTOR RELATED, ISOFORM J transmembrane signaling receptor activity#GO:0004888;protein kinase activity#GO:0004672;transmembrane receptor protein tyrosine kinase activity#GO:0004714;molecular transducer activity#GO:0060089;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;protein tyrosine kinase activity#GO:0004713;catalytic activity#GO:0003824;transferase activity#GO:0016740;transmembrane receptor protein kinase activity#GO:0019199;signaling receptor activity#GO:0038023;catalytic activity, acting on a protein#GO:0140096 regulation of intracellular signal transduction#GO:1902531;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;cell communication#GO:0007154;positive regulation of signaling#GO:0023056;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of signal transduction#GO:0009967;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of MAPK cascade#GO:0043408;positive regulation of intracellular signal transduction#GO:1902533;cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;positive regulation of MAPK cascade#GO:0043410;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;positive regulation of response to stimulus#GO:0048584;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8042806|UniProtKB=A0ACM8DTY2 A0ACM8DTY2 LOC8042806 PTHR12877:SF7 RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR DH DOMAIN-CONTAINING PROTEIN guanyl-nucleotide exchange factor activity#GO:0005085;molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234 regulation of actin filament-based process#GO:0032970;positive regulation of actin filament bundle assembly#GO:0032233;cellular component organization or biogenesis#GO:0071840;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;positive regulation of cellular component biogenesis#GO:0044089;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of stress fiber assembly#GO:0051492;regulation of cellular component biogenesis#GO:0044087;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC121835992|UniProtKB=A0ACM8FWP0 A0ACM8FWP0 LOC121835992 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8038942|UniProtKB=A0ACM8DKA6 A0ACM8DKA6 LOC8038942 PTHR46466:SF1 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 GLYOXALASE DOMAIN-CONTAINING PROTEIN 4 IXOSC|EnsemblGenome=LOC120843466|UniProtKB=A0ACM8EW77 A0ACM8EW77 LOC120843466 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115326941|UniProtKB=A0ACM8E6I7 A0ACM8E6I7 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8027770|UniProtKB=A0ACM8E1J7 A0ACM8E1J7 LOC8027770 PTHR45942:SF1 Calcineurin subunit B PROTEIN PHOSPHATASE 3 REGULATORY SUBUNIT B, ALPHA phosphatase binding#GO:0019902;binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;protein phosphatase regulator activity#GO:0019888;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772 calcium-mediated signaling#GO:0019722;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;calcineurin-mediated signaling#GO:0097720;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494 Wnt signaling pathway#P00057>Calcineurin#P01446 IXOSC|EnsemblGenome=LOC8041818|UniProtKB=A0ACM8DSG2 A0ACM8DSG2 Fic PTHR13504:SF34 FIDO DOMAIN-CONTAINING PROTEIN DDB_G0283145 PROTEIN ADENYLYLTRANSFERASE FICD catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 IXOSC|EnsemblGenome=LOC120839018|UniProtKB=A0ACM8FSW0 A0ACM8FSW0 LOC120839018 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8030189|UniProtKB=A0ACM8EEE7 A0ACM8EEE7 Klp3A PTHR47969:SF15 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;isomerase activity#GO:0016853;microtubule motor activity#GO:0003777;cytoskeletal motor activity#GO:0003774 mitotic cell cycle process#GO:1903047;microtubule-based process#GO:0007017;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;spindle elongation#GO:0051231;cellular process#GO:0009987;organelle organization#GO:0006996;microtubule cytoskeleton organization#GO:0000226;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043 microtubule cytoskeleton#GO:0015630;cellular anatomical structure#GO:0110165;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 microtubule binding motor protein#PC00156;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120845334|UniProtKB=A0ACM8F0L5 A0ACM8F0L5 LOC120845334 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115328560|UniProtKB=A0ACM8E9N0 A0ACM8E9N0 LOC115328560 PTHR48078:SF2 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED CATABOLIC L-SERINE_THREONINE DEHYDRATASE catalytic activity#GO:0003824;lyase activity#GO:0016829 proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;branched-chain amino acid biosynthetic process#GO:0009082;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;aspartate family amino acid biosynthetic process#GO:0009067;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 lyase#PC00144;dehydratase#PC00091 IXOSC|EnsemblGenome=LOC120839580|UniProtKB=A0ACM8EMP6 A0ACM8EMP6 LOC120839580 PTHR19303:SF82 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115318624|UniProtKB=A0ACM8DYS2 A0ACM8DYS2 LOC115318624 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8028096|UniProtKB=A0ACM8EV33 A0ACM8EV33 LOC8028096 PTHR44395:SF1 FAMILY NOT NAMED PROTEIN O-MANNOSYL-TRANSFERASE TMTC3 IXOSC|EnsemblGenome=LOC8041399|UniProtKB=A0ACM8DKP5 A0ACM8DKP5 LOC8041399 PTHR21377:SF1 PROTEIN FAM210B, MITOCHONDRIAL MITOCHONDRIAL INNER MEMBRANE SCAFFOLD 1 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8031511|UniProtKB=A0ACM8DIB5 A0ACM8DIB5 LOC8031511 PTHR21382:SF1 NADH-UBIQUINONE OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 11 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;respiratory chain complex#GO:0098803;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8027932|UniProtKB=A0ACM8G3L3 A0ACM8G3L3 Mical PTHR23167:SF95 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED F-ACTIN MONOOXYGENASE cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;cellular process#GO:0009987;actin filament-based process#GO:0030029;organelle organization#GO:0006996;cellular component organization#GO:0016043 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120847394|UniProtKB=A0ACM8F437 A0ACM8F437 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 nucleobase-containing compound metabolic process#GO:0006139;DNA damage response#GO:0006974;DNA repair#GO:0006281;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;homologous recombination#GO:0035825;reproductive process#GO:0022414;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982;organelle fission#GO:0048285;cellular process#GO:0009987;organelle organization#GO:0006996;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;DNA recombination#GO:0006310;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;cell cycle process#GO:0022402;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nuclear division#GO:0000280 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8029694|UniProtKB=A0ACM8FLN1 A0ACM8FLN1 LOC8029694 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8042725|UniProtKB=A0ACM8DL01 A0ACM8DL01 Ciao1 PTHR19920:SF0 WD40 PROTEIN CIAO1 CYTOSOLIC IRON-SULFUR PROTEIN ASSEMBLY PROTEIN CIAO1-RELATED cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8027108|UniProtKB=A0ACM8EA13 A0ACM8EA13 Non1 PTHR45759:SF1 NUCLEOLAR GTP-BINDING PROTEIN 1 GTP-BINDING PROTEIN 4 ribonucleoside triphosphate phosphatase activity#GO:0017111;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;RNA binding#GO:0003723;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleic acid binding#GO:0003676;binding#GO:0005488;GTPase activity#GO:0003924 cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;cellular component biogenesis#GO:0044085;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC120847711|UniProtKB=A0ACM8F4E6 A0ACM8F4E6 LOC120847711 PTHR47535:SF1 MUSCLE-SPECIFIC PROTEIN 300 KDA, ISOFORM G MUSCLE-SPECIFIC PROTEIN 300 KDA protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488 cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;organelle localization#GO:0051640;intracellular transport#GO:0046907;transport#GO:0006810;establishment of organelle localization#GO:0051656;cellular process#GO:0009987;nuclear migration#GO:0007097;establishment of localization in cell#GO:0051649 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;nuclear protein-containing complex#GO:0140513;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;nuclear membrane#GO:0031965;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737;nuclear envelope#GO:0005635;membrane#GO:0016020;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115316618|UniProtKB=A0ACM8DWK1 A0ACM8DWK1 LOC115316618 PTHR10910:SF107 EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN DOUBLE-STRANDED RNA-SPECIFIC ADENOSINE DEAMINASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;double-stranded RNA binding#GO:0003725;tRNA-specific adenosine deaminase activity#GO:0008251;binding#GO:0005488;nucleic acid binding#GO:0003676;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;RNA binding#GO:0003723 RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;adenosine to inosine editing#GO:0006382;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;base conversion or substitution editing#GO:0016553;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115319688|UniProtKB=A0ACM8EGR8 A0ACM8EGR8 LOC115319688 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849074|UniProtKB=A0ACM8G898 A0ACM8G898 LOC120849074 PTHR24404:SF114 ZINC FINGER PROTEIN RH47711P-RELATED DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115308712|UniProtKB=A0ACM8DMY3 A0ACM8DMY3 RpL30 PTHR11449:SF1 RIBOSOMAL PROTEIN L30 LARGE RIBOSOMAL SUBUNIT PROTEIN EL30 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120846700|UniProtKB=A0ACM8F3V3 A0ACM8F3V3 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120842769|UniProtKB=A0ACM8EUE8 A0ACM8EUE8 ksr PTHR44329:SF298 SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED SERINE_THREONINE-PROTEIN KINASE DRKD-RELATED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;cell communication#GO:0007154 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120844762|UniProtKB=A0ACM8F0M0 A0ACM8F0M0 LOC120844762 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120842282|UniProtKB=A0ACM8ETH5 A0ACM8ETH5 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029725|UniProtKB=A0ACM8E0Q8 A0ACM8E0Q8 LOC8029725 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115315684|UniProtKB=A0ACM8G8Y9 A0ACM8G8Y9 LOC115315684 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC120837792|UniProtKB=A0ACM8EIE4 A0ACM8EIE4 LOC120837792 PTHR22972:SF7 SERINE/THREONINE PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE PINK1, MITOCHONDRIAL phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 regulation of organelle organization#GO:0033043;regulation of mitochondrion organization#GO:0010821;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;regulation of developmental process#GO:0050793;regulation of mitochondrial fission#GO:0090140;positive regulation of mitochondrial fission#GO:0090141;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;catabolic process#GO:0009056;positive regulation of cellular component organization#GO:0051130;process utilizing autophagic mechanism#GO:0061919;positive regulation of organelle organization#GO:0010638;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;autophagy#GO:0006914;positive regulation of cellular process#GO:0048522;biological regulation#GO:0065007;regulation of apoptotic process#GO:0042981;positive regulation of developmental process#GO:0051094;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;regulation of anatomical structure morphogenesis#GO:0022603 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120849962|UniProtKB=A0ACM8F8X3 A0ACM8F8X3 LOC120849962 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8052433|UniProtKB=A0ACM8DLQ0 A0ACM8DLQ0 LOC8052433 PTHR45842:SF12 SYNAPTIC ADHESION-LIKE MOLECULE SALM TIR DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121835847|UniProtKB=A0ACM8FW11 A0ACM8FW11 LOC121835847 PTHR35001:SF6 COLLAGEN IV NC1 DOMAIN-CONTAINING PROTEIN RIBOSOME-BINDING PROTEIN 1 IXOSC|EnsemblGenome=LOC8039391|UniProtKB=A0ACM8DXG5 A0ACM8DXG5 LOC8039391 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121833399|UniProtKB=A0ACM8FKV0 A0ACM8FKV0 LOC121833399 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316947|UniProtKB=A0ACM8DX76 A0ACM8DX76 LOC115316947 PTHR12253:SF34 RH14732P PHOSPHOLIPASE A2 IXOSC|EnsemblGenome=LOC8026559|UniProtKB=A0ACM8DX11 A0ACM8DX11 LOC8026559 PTHR47143:SF3 TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL PROTEIN PAINLESS ION_TRANS DOMAIN-CONTAINING PROTEIN transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular process#GO:0009987;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;membrane protein complex#GO:0098796;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495 ion channel#PC00133 IXOSC|EnsemblGenome=LOC121833034|UniProtKB=A0ACM8FIZ1 A0ACM8FIZ1 LOC121833034 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115320976|UniProtKB=A0ACM8E1D9 A0ACM8E1D9 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8033667|UniProtKB=A0ACM8EVF3 A0ACM8EVF3 LOC8033667 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115316930|UniProtKB=A0ACM8DWJ6 A0ACM8DWJ6 LOC115316930 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8054090|UniProtKB=A0ACM8FEB4 A0ACM8FEB4 LOC8054090 PTHR24169:SF28 NUCLEAR FACTOR NF-KAPPA-B PROTEIN DORSAL-RELATED IMMUNITY FACTOR DIF-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of macromolecule metabolic process#GO:0010604;intracellular signaling cassette#GO:0141124;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;cellular response to stimulus#GO:0051716;regulation of DNA-templated transcription#GO:0006355;cell communication#GO:0007154;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 Rel homology transcription factor#PC00252;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 Toll pathway-drosophila#P06217>DL#P06344;Toll receptor signaling pathway#P00054>NFkappaB#P01354 IXOSC|EnsemblGenome=LOC121837552|UniProtKB=A0ACM8G3Y3 A0ACM8G3Y3 LOC121837553 PTHR19303:SF82 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115315548|UniProtKB=A0ACM8FV50 A0ACM8FV50 LOC115315548 PTHR13245:SF14 RRP15-LIKE PROTEIN RRP15-LIKE PROTEIN maturation of 5.8S rRNA#GO:0000460;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 IXOSC|EnsemblGenome=LOC8052702|UniProtKB=A0ACM8DGK4 A0ACM8DGK4 Trs20 PTHR12403:SF1 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 2-RELATED endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147 Golgi apparatus#GO:0005794;vesicle tethering complex#GO:0099023;intracellular protein-containing complex#GO:0140535;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;TRAPPII protein complex#GO:1990071;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8041300|UniProtKB=A0ACM8EY02 A0ACM8EY02 PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC115324575|UniProtKB=A0ACM8E433 A0ACM8E433 LOC115324575 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837489|UniProtKB=A0ACM8EHH4 A0ACM8EHH4 LOC120837489 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318864|UniProtKB=A0ACM8DZ82 A0ACM8DZ82 LOC115318864 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298 cellular process#GO:0009987;lipid metabolic process#GO:0006629;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 IXOSC|EnsemblGenome=LOC8043831|UniProtKB=A0ACM8DT16 A0ACM8DT16 LOC8043831 PTHR24036:SF13 SKELETOR-RELATED PROTEIN SKELETOR, ISOFORMS D_E transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8041302|UniProtKB=A0ACM8FS85 A0ACM8FS85 LOC8041302 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;synapse organization#GO:0050808;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cell projection membrane#GO:0031253;neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256 IXOSC|EnsemblGenome=LOC8039777|UniProtKB=A0ACM8FXP3 A0ACM8FXP3 LOC8039777 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040801|UniProtKB=A0ACM8DY38 A0ACM8DY38 LOC8040801 PTHR24104:SF48 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED E3 UBIQUITIN-PROTEIN LIGASE TRIM71 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659 catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8044008|UniProtKB=A0ACM8ECP3 A0ACM8ECP3 LOC8044008 PTHR46690:SF1 CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG CYTOCHROME C OXIDASE ASSEMBLY FACTOR 6 HOMOLOG oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096;protein-disulfide reductase activity#GO:0015035;disulfide oxidoreductase activity#GO:0015036;catalytic activity#GO:0003824;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular component assembly#GO:0022607;cytochrome complex assembly#GO:0017004;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;cellular component organization or biogenesis#GO:0071840 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120839754|UniProtKB=A0ACM8ENM9 A0ACM8ENM9 LOC120839754 PTHR11548:SF2 THYMIDYLATE SYNTHASE 1 THYMIDYLATE SYNTHASE transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleoside monophosphate biosynthetic process#GO:0009124;nucleotide biosynthetic process#GO:0009165;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 Formyltetrahydrofolate biosynthesis#P02743>Thymidylate synthase#P02954;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate synthase#P02943;De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>Thymidylate synthase#P02913;Tetrahydrofolate biosynthesis#P02742>Dihydrofolate reductase#P02948;Formyltetrahydrofolate biosynthesis#P02743>Dihydrofolate reductase#P02957 IXOSC|EnsemblGenome=LOC121833714|UniProtKB=A0ACM8FND3 A0ACM8FND3 Gdap1 PTHR44188:SF1 GDAP1, ISOFORM A GDAP1, ISOFORM A cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;mitochondrial fission#GO:0000266;organelle fusion#GO:0048284;mitochondrion organization#GO:0007005;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;outer membrane#GO:0019867;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;mitochondrial outer membrane#GO:0005741;cytoplasm#GO:0005737;organelle outer membrane#GO:0031968;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8042930|UniProtKB=A0ACM8F9T4 A0ACM8F9T4 LOC8042930 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313243|UniProtKB=A0ACM8EU23 A0ACM8EU23 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8025920|UniProtKB=A0ACM8DGQ8 A0ACM8DGQ8 LOC8025920 PTHR11685:SF479 RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING E3 UBIQUITIN-PROTEIN LIGASE RNF217 catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein binding#GO:0005515;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;acyltransferase activity#GO:0016746;binding#GO:0005488;ubiquitin-like protein transferase activity#GO:0019787;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056 ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8044146|UniProtKB=A0ACM8G822 A0ACM8G822 LOC8044146 PTHR46025:SF3 XYLOSYLTRANSFERASE OXT XYLOSYLTRANSFERASE OXT transferase#PC00220 IXOSC|EnsemblGenome=LOC8032802|UniProtKB=A0ACM8DQV8 A0ACM8DQV8 LOC8032802 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;metabolic process#GO:0008152;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790 transferase#PC00220 IXOSC|EnsemblGenome=LOC115318623|UniProtKB=A0ACM8DZ01 A0ACM8DZ01 LOC115318623 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8028628|UniProtKB=A0ACM8E7F5 A0ACM8E7F5 LOC8028628 PTHR24238:SF85 G-PROTEIN COUPLED RECEPTOR OREXIN RECEPTOR TYPE 2-LIKE PROTEIN transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;neuropeptide signaling pathway#GO:0007218;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8051967|UniProtKB=A0ACM8F7F3 A0ACM8F7F3 LOC8051967 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 glutathione transferase activity#GO:0004364;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 transferase#PC00220 IXOSC|EnsemblGenome=LOC8038642|UniProtKB=A0ACM8FT67 A0ACM8FT67 LOC8038642 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 neuron projection membrane#GO:0032589;leading edge membrane#GO:0031256;cell projection membrane#GO:0031253;membrane#GO:0016020;cell leading edge#GO:0031252;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8024278|UniProtKB=A0ACM8FTR9 A0ACM8FTR9 LOC8024278 PTHR11219:SF72 TENEURIN AND N-ACETYLGLUCOSAMINE-1-PHOSPHODIESTER ALPHA-N-ACETYLGLUCOSAMINIDASE TENEURIN-M binding#GO:0005488;signaling receptor binding#GO:0005102;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;cell-cell adhesion#GO:0098609;neuron projection development#GO:0031175;cellular process#GO:0009987;neuron development#GO:0048666;axonogenesis#GO:0007409;synaptic membrane adhesion#GO:0099560;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;neuron projection guidance#GO:0097485;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;anatomical structure development#GO:0048856;system development#GO:0048731;synapse organization#GO:0050808;cell junction organization#GO:0034330 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;synapse#GO:0045202;cellular anatomical structure#GO:0110165;glutamatergic synapse#GO:0098978;plasma membrane bounded cell projection#GO:0120025;plasma membrane#GO:0005886;cell projection#GO:0042995;cell junction#GO:0030054 IXOSC|EnsemblGenome=LOC8039495|UniProtKB=A0ACM8E8P2 A0ACM8E8P2 LOC8039495 PTHR21084:SF1 DENSE INCISORS SIMILAR TO HUMAN CHROMOSOME 3 OPEN READING FRAME 38 IXOSC|EnsemblGenome=LOC8040145|UniProtKB=A0ACM8F7D1 A0ACM8F7D1 LOC8040145 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115327460|UniProtKB=A0ACM8E739 A0ACM8E739 LOC115327460 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8051914|UniProtKB=A0ACM8FUX1 A0ACM8FUX1 LOC8051914 PTHR47969:SF21 CHROMOSOME-ASSOCIATED KINESIN KIF4A-RELATED KINESIN-LIKE PROTEIN cytoskeletal protein#PC00085;microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC8032520|UniProtKB=A0ACM8DJH5 A0ACM8DJH5 Pkc53E PTHR24356:SF390 SERINE/THREONINE-PROTEIN KINASE PROTEIN KINASE C, BRAIN ISOZYME-RELATED protein serine/threonine kinase activity#GO:0004674;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 non-receptor serine/threonine protein kinase#PC00167 Endothelin signaling pathway#P00019>PKC#P00568;5HT2 type receptor mediated signaling pathway#P04374>PKC#P04420;Wnt signaling pathway#P00057>Protein Kinase C#P01458;Oxytocin receptor mediated signaling pathway#P04391>PKC#P04533;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>PKC#P01074;Alzheimer disease-amyloid secretase pathway#P00003>PKC#P00109;PDGF signaling pathway#P00047>PKC#P01150;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PKC#P04583;FGF signaling pathway#P00021>PKC#P00648;Apoptosis signaling pathway#P00006>PKCs#P00318;VEGF signaling pathway#P00056>PKC#P01425;Angiogenesis#P00005>PKC#P00219;Histamine H1 receptor mediated signaling pathway#P04385>PKC#P04487;EGF receptor signaling pathway#P00018>PKC#P00565 IXOSC|EnsemblGenome=LOC121835030|UniProtKB=A0ACM8FRZ8 A0ACM8FRZ8 LOC121835030 PTHR24348:SF65 SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED SERINE_THREONINE-PROTEIN KINASE ULK3 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 response to stimulus#GO:0050896;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;piecemeal microautophagy of the nucleus#GO:0034727;response to starvation#GO:0042594;regulation of autophagy#GO:0010506;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;biological regulation#GO:0065007;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to nutrient levels#GO:0031667;regulation of metabolic process#GO:0019222;reticulophagy#GO:0061709;response to stress#GO:0006950;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagosome assembly#GO:0000045;regulation of catabolic process#GO:0009894;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422 cytosol#GO:0005829;membrane#GO:0016020;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;phagophore assembly site#GO:0000407;autophagosome#GO:0005776;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8029927|UniProtKB=A0ACM8DP84 A0ACM8DP84 LOC8029927 PTHR46131:SF1 SD08549P SD08549P nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;purine nucleotide transmembrane transporter activity#GO:0015216;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC115313856|UniProtKB=A0ACM8DT53 A0ACM8DT53 PTHR13530:SF3 TBC1 DOMAIN FAMILY MEMBER 7 TBC1 DOMAIN FAMILY MEMBER 7 enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein-containing complex binding#GO:0044877;binding#GO:0005488;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of TOR signaling#GO:0032006;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;negative regulation of TOR signaling#GO:0032007;regulation of cell communication#GO:0010646;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8042613|UniProtKB=A0ACM8DKY3 A0ACM8DKY3 LOC8042613 PTHR24114:SF50 LEUCINE RICH REPEAT FAMILY PROTEIN LEUCINE-RICH REPEAT-CONTAINING PROTEIN 74A IXOSC|EnsemblGenome=LOC8038919|UniProtKB=A0ACM8E3N4 A0ACM8E3N4 LOC8038919 PTHR23023:SF317 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8041414|UniProtKB=A0ACM8EA48 A0ACM8EA48 LOC8041414 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115318794|UniProtKB=A0ACM8DY87 A0ACM8DY87 LOC115318794 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8026709|UniProtKB=A0ACM8E5K9 A0ACM8E5K9 LOC8026709 PTHR21686:SF12 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 2 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC121048504|UniProtKB=A0ACM8FIL6 A0ACM8FIL6 LOC121048504 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052911|UniProtKB=A0ACM8DUT2 A0ACM8DUT2 Fntb PTHR11774:SF6 GERANYLGERANYL TRANSFERASE TYPE BETA SUBUNIT PROTEIN FARNESYLTRANSFERASE SUBUNIT BETA prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8043040|UniProtKB=A0ACM8FGT1 A0ACM8FGT1 LOC8043040 PTHR15326:SF2 SPERMATOGENESIS-ASSOCIATED PROTEIN 2/TAMOZHENNIC PROTEIN TAMOZHENNIC intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115330814|UniProtKB=A0ACM8FA07 A0ACM8FA07 LOC115330814 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8034978|UniProtKB=A0ACM8E508 A0ACM8E508 LOC8034978 PTHR22811:SF59 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN GOLD DOMAIN-CONTAINING PROTEIN-RELATED molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 cellular component organization#GO:0016043;Golgi organization#GO:0007030;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;protein transport#GO:0015031;vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular protein transport#GO:0006886 intracellular organelle#GO:0043229;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasm#GO:0005737 membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC120844172|UniProtKB=A0ACM8EY13 A0ACM8EY13 LOC120844172 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8026258|UniProtKB=A0ACM8F8H0 A0ACM8F8H0 PTHR28358:SF1 TRANSMEMBRANE PROTEIN 127 TRANSMEMBRANE PROTEIN 127 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of TOR signaling#GO:0032006;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8053007|UniProtKB=A0ACM8DYM5 A0ACM8DYM5 LOC8053007 PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121046885|UniProtKB=A0ACM8FDT3 A0ACM8FDT3 LOC121046885 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8050429|UniProtKB=A0ACM8DZ23 A0ACM8DZ23 Pgant35A PTHR11675:SF63 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;hexosyltransferase activity#GO:0016758;catalytic activity#GO:0003824;transferase activity#GO:0016740;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 biosynthetic process#GO:0009058;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;glycoprotein biosynthetic process#GO:0009101;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;regulation of response to stimulus#GO:0048583;glycoprotein metabolic process#GO:0009100;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;regulation of signaling#GO:0023051;regulation of Notch signaling pathway#GO:0008593 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121835461|UniProtKB=A0ACM8FVA1 A0ACM8FVA1 LOC121835461 PTHR12619:SF32 RFX TRANSCRIPTION FACTOR FAMILY DNA-BINDING PROTEIN RFX6 cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC115324016|UniProtKB=A0ACM8FBF8 A0ACM8FBF8 PTHR47972:SF45 KINESIN-LIKE PROTEIN KLP-3 PROTEIN CLARET SEGREGATIONAL microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC120844449|UniProtKB=A0ACM8EZT2 A0ACM8EZT2 LOC120844449 PTHR46481:SF16 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 BED-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832982|UniProtKB=A0ACM8FSB1 A0ACM8FSB1 LOC121832982 PTHR45624:SF61 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER L-amino acid transmembrane transporter activity#GO:0015179;basic amino acid transmembrane transporter activity#GO:0015174;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;amino acid transmembrane transporter activity#GO:0015171 carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;L-alpha-amino acid transmembrane transport#GO:1902475;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;cellular localization#GO:0051641;mitochondrial transmembrane transport#GO:1990542;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;L-amino acid transport#GO:0015807;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;amino acid transport#GO:0006865;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;intracellular transport#GO:0046907 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC8038943|UniProtKB=A0ACM8E417 A0ACM8E417 LOC8038943 PTHR46179:SF34 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 423 HOMOLOG transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8052551|UniProtKB=A0ACM8DM17 A0ACM8DM17 LOC8052551 PTHR10129:SF48 TRANSCRIPTION FACTOR MAF MAF-S, ISOFORM B sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC8036435|UniProtKB=A0ACM8G2S4 A0ACM8G2S4 LOC8036435 PTHR11831:SF1 30S 40S RIBOSOMAL PROTEIN U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP3 rRNA binding#GO:0019843;structural constituent of ribosome#GO:0003735;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676;binding#GO:0005488;structural molecule activity#GO:0005198;RNA binding#GO:0003723 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;90S preribosome#GO:0030686;ribosome#GO:0005840;small-subunit processome#GO:0032040;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121833965|UniProtKB=A0ACM8FNH4 A0ACM8FNH4 PTHR24399:SF70 ZINC FINGER AND BTB DOMAIN-CONTAINING C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription repressor activity#GO:0001217;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;nucleic acid binding#GO:0003676 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8033996|UniProtKB=A0ACM8E0W0 A0ACM8E0W0 LOC8033996 PTHR46321:SF1 KIF1-BINDING PROTEIN KIF-BINDING PROTEIN multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;central nervous system neuron differentiation#GO:0021953;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis#GO:0000902;central nervous system development#GO:0007417;cell projection organization#GO:0030030;cell differentiation#GO:0030154;neuron projection organization#GO:0106027;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 IXOSC|EnsemblGenome=LOC8024422|UniProtKB=A0ACM8EHG6 A0ACM8EHG6 LOC8024422 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8042552|UniProtKB=A0ACM8E7H6 A0ACM8E7H6 PTHR24251:SF28 OVOCHYMASE-RELATED NEUROPILIN AND TOLLOID-LIKE, ISOFORM B protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8024771|UniProtKB=A0ACM8EAT2 A0ACM8EAT2 LOC8024771 PTHR23255:SF98 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE PUT signaling receptor activity#GO:0038023;transferase activity#GO:0016740;kinase activity#GO:0016301;activin binding#GO:0048185;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane signaling receptor activity#GO:0004888;catalytic activity, acting on a protein#GO:0140096;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;molecular transducer activity#GO:0060089 cellular response to growth factor stimulus#GO:0071363;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cell communication#GO:0007154;activin receptor signaling pathway#GO:0032924;pattern specification process#GO:0007389;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;multicellular organism development#GO:0007275;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;cellular process#GO:0009987;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;protein kinase complex#GO:1902911;serine/threonine protein kinase complex#GO:1902554;transferase complex, transferring phosphorus-containing groups#GO:0061695;signaling receptor complex#GO:0043235;transferase complex#GO:1990234;catalytic complex#GO:1902494 serine/threonine protein kinase receptor#PC00205 TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;ALP23B signaling pathway#P06209>PUT#P06218;GBB signaling pathway#P06214>PUT#P06304;SCW signaling pathway#P06216>PUT#P06320;DPP signaling pathway#P06213>PUT#P06277;DPP-SCW signaling pathway#P06212>PUT#P06270;BMP/activin signaling pathway-drosophila#P06211>TGFbetaR II#P06255;Activin beta signaling pathway#P06210>PUT#P06229 IXOSC|EnsemblGenome=LOC120841900|UniProtKB=A0ACM8ESR9 A0ACM8ESR9 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121833116|UniProtKB=A0ACM8FJB0 A0ACM8FJB0 LOC121833116 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120839299|UniProtKB=A0ACM8FV98 A0ACM8FV98 LOC120839299 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040025|UniProtKB=A0ACM8E264 A0ACM8E264 PTHR15598:SF5 ENHANCER OF MRNA-DECAPPING PROTEIN 4 ENHANCER OF MRNA-DECAPPING PROTEIN 4 molecular condensate scaffold activity#GO:0140693;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;RNA decapping#GO:0110154;negative regulation of biological process#GO:0048519;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 mRNA capping factor#PC00145 IXOSC|EnsemblGenome=LOC8026413|UniProtKB=A0ACM8DHR5 A0ACM8DHR5 LOC8026413 PTHR28671:SF3 COILED-COIL DOMAIN-CONTAINING PROTEIN 169 COILED-COIL DOMAIN-CONTAINING PROTEIN 169 IXOSC|EnsemblGenome=LOC8025340|UniProtKB=A0ACM8E6A8 A0ACM8E6A8 LOC8025340 PTHR45629:SF13 SNF2/RAD54 FAMILY MEMBER DNA EXCISION REPAIR PROTEIN ERCC-6-LIKE DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097 nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170 damaged DNA-binding protein#PC00086 IXOSC|EnsemblGenome=LOC115312311|UniProtKB=A0ACM8EWX9 A0ACM8EWX9 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323029|UniProtKB=A0ACM8EQM0 A0ACM8EQM0 LOC115323029 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;cellular localization#GO:0051641;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;regulation of macromolecule metabolic process#GO:0060255;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;membrane organization#GO:0061024;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;intracellular protein localization#GO:0008104;nucleus organization#GO:0006997;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;transport#GO:0006810;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907 nucleus#GO:0005634;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear periphery#GO:0034399;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC8029848|UniProtKB=A0ACM8E2F2 A0ACM8E2F2 PTHR47330:SF1 POLY(U)-BINDING-SPLICING FACTOR PUF60-B-RELATED POLY(U)-BINDING-SPLICING FACTOR PUF60 regulation of alternative mRNA splicing, via spliceosome#GO:0000381;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;spliceosomal complex assembly#GO:0000245;mRNA metabolic process#GO:0016071;ribonucleoprotein complex biogenesis#GO:0022613;regulation of biological process#GO:0050789;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;alternative mRNA splicing, via spliceosome#GO:0000380;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826;regulation of mRNA metabolic process#GO:1903311;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;mRNA splice site recognition#GO:0006376;cellular component assembly#GO:0022607;gene expression#GO:0010467;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;regulation of RNA metabolic process#GO:0051252;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC121047334|UniProtKB=A0ACM8FGX7 A0ACM8FGX7 LOC121047334 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318065|UniProtKB=A0ACM8DXR4 A0ACM8DXR4 LOC115318065 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8042510|UniProtKB=A0ACM8EPZ6 A0ACM8EPZ6 LOC8042510 PTHR24328:SF7 HOMEOBOX PROTEIN MOX BUTTONLESS RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC120846059|UniProtKB=A0ACM8F1C3 A0ACM8F1C3 LOC120846059 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8038672|UniProtKB=A0ACM8DSB0 A0ACM8DSB0 LOC8038672 PTHR24351:SF289 RIBOSOMAL PROTEIN S6 KINASE CHROMOSOMAL SERINE_THREONINE-PROTEIN KINASE JIL-1 catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;TORC1 signaling#GO:0038202;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;TOR signaling#GO:0031929;regulation of nucleobase-containing compound metabolic process#GO:0019219;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260 PDGF signaling pathway#P00047>p90RSK#P01142;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888 IXOSC|EnsemblGenome=LOC115321432|UniProtKB=A0ACM8E132 A0ACM8E132 LOC121835354 PTHR10529:SF262 AP COMPLEX SUBUNIT MU ADAPTOR PROTEIN COMPLEX 1, MU SUBUNIT protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;cargo adaptor activity#GO:0140312 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular localization#GO:0051641;Golgi to vacuole transport#GO:0006896;establishment of localization#GO:0051234;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034 Golgi-associated vesicle#GO:0005798;trans-Golgi network transport vesicle membrane#GO:0012510;Golgi apparatus#GO:0005794;clathrin-coated vesicle#GO:0030136;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;transport vesicle membrane#GO:0030658;trans-Golgi network transport vesicle#GO:0030140;AP-1 adaptor complex#GO:0030121;membrane coat#GO:0030117;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane protein complex#GO:0098796;vesicle#GO:0031982;intracellular membrane-bounded organelle#GO:0043231;clathrin vesicle coat#GO:0030125;clathrin-coated vesicle membrane#GO:0030665;AP-type membrane coat adaptor complex#GO:0030119;bounding membrane of organelle#GO:0098588;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;vesicle coat#GO:0030120;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;coated membrane#GO:0048475;organelle subcompartment#GO:0031984;coated vesicle#GO:0030135;intracellular vesicle#GO:0097708;organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8041303|UniProtKB=A0ACM8EUW7 A0ACM8EUW7 LOC8041303 PTHR43615:SF1 PHOSPHOENOLPYRUVATE SYNTHASE-RELATED PHOSPHOENOLPYRUVATE SYNTHASE IXOSC|EnsemblGenome=LOC115329663|UniProtKB=A0ACM8E9Y6 A0ACM8E9Y6 LOC115329663 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837259|UniProtKB=A0ACM8EH01 A0ACM8EH01 LOC120837259 PTHR23430:SF50 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;heterochromatin formation#GO:0031507;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;cellular component assembly#GO:0022607;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of cellular process#GO:0048523 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;protein-DNA complex#GO:0032993;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nucleosome#GO:0000786;intracellular membrane-bounded organelle#GO:0043231 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8035192|UniProtKB=A0ACM8DJS3 A0ACM8DJS3 P5cr-2 PTHR11645:SF0 PYRROLINE-5-CARBOXYLATE REDUCTASE PYRROLINE-5-CARBOXYLATE REDUCTASE oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;amino acid biosynthetic process#GO:0008652;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 metabolite interconversion enzyme#PC00262;reductase#PC00198 Proline biosynthesis#P02768>Pyrroline-5-carboxylate reductase#P03113 IXOSC|EnsemblGenome=LOC8033489|UniProtKB=A0ACM8DRK3 A0ACM8DRK3 LOC8033489 PTHR10468:SF12 PROTEIN O-LINKED-MANNOSE BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE 1/ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE ALPHA-1,3-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120840446|UniProtKB=A0ACM8EP94 A0ACM8EP94 LOC120840446 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 carbohydrate catabolic process#GO:0016052;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;primary metabolic process#GO:0044238;hexose metabolic process#GO:0019318 hydrolase#PC00121;galactosidase#PC00104 IXOSC|EnsemblGenome=LOC8025391|UniProtKB=A0ACM8EC49 A0ACM8EC49 LOC8025391 PTHR13554:SF10 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5-RELATED 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 5 protease#PC00190 IXOSC|EnsemblGenome=LOC115324825|UniProtKB=A0ACM8G372 A0ACM8G372 LOC115324825 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120850326|UniProtKB=A0ACM8F9L0 A0ACM8F9L0 LOC120850326 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8031902|UniProtKB=A0ACM8FUC7 A0ACM8FUC7 LOC8031902 PTHR12577:SF6 DACHSHUND DACHSHUND, ISOFORM B sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218;winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8025101|UniProtKB=A0ACM8FKP4 A0ACM8FKP4 LOC8025101 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transporter#PC00227 IXOSC|EnsemblGenome=LOC115325916|UniProtKB=A0ACM8FCW1 A0ACM8FCW1 LOC115325916 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC115331138|UniProtKB=A0ACM8ECP1 A0ACM8ECP1 LOC115331138 PTHR43503:SF4 MCG48959-RELATED PEROXIREDOXIN-6 catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684 cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 peroxidase#PC00180;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053318|UniProtKB=A0ACM8DY18 A0ACM8DY18 LOC8053318 PTHR24104:SF20 E3 UBIQUITIN-PROTEIN LIGASE NHLRC1-RELATED RING-TYPE DOMAIN-CONTAINING PROTEIN ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115332509|UniProtKB=A0ACM8EUM6 A0ACM8EUM6 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8029144|UniProtKB=A0ACM8E0Q6 A0ACM8E0Q6 ssp6 PTHR15963:SF5 GENERAL RECEPTOR FOR PHOSPHOINOSITIDES 1-ASSOCIATED SCAFFOLD PROTEIN-RELATED SHORT SPINDLE 6, ISOFORM A IXOSC|EnsemblGenome=LOC8029213|UniProtKB=A0ACM8DPJ6 A0ACM8DPJ6 LOC8029213 PTHR12682:SF11 ARCHEASE TRNA-SPLICING LIGASE-ACTIVATING FACTOR ARCHEASE catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535 IXOSC|EnsemblGenome=LOC115322958|UniProtKB=A0ACM8EKH9 A0ACM8EKH9 LOC115322958 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8042989|UniProtKB=A0ACM8ED86 A0ACM8ED86 PTHR13367:SF35 UBIQUITIN THIOESTERASE UBIQUITIN THIOESTERASE TRABID deubiquitinase activity#GO:0101005;hydrolase activity#GO:0016787;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;ubiquitin-like protein peptidase activity#GO:0019783 protein modification by small protein conjugation or removal#GO:0070647;modification-dependent macromolecule catabolic process#GO:0043632;regulation of signaling#GO:0023051;protein catabolic process#GO:0030163;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;regulation of Wnt signaling pathway#GO:0030111;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of Wnt signaling pathway#GO:0030177;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification process#GO:0036211;primary metabolic process#GO:0044238;positive regulation of signal transduction#GO:0009967;modification-dependent protein catabolic process#GO:0019941;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;catabolic process#GO:0009056;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;post-translational protein modification#GO:0043687;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC115328997|UniProtKB=A0ACM8G7H4 A0ACM8G7H4 LOC115328997 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024778|UniProtKB=A0ACM8FU47 A0ACM8FU47 LOC8024778 PTHR10856:SF44 CORONIN CORONIN binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;actin filament binding#GO:0051015;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;actin filament-based process#GO:0030029;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987 supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;actin cytoskeleton#GO:0015629;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;actin filament#GO:0005884;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;cell periphery#GO:0071944;membrane#GO:0016020 non-motor actin binding protein#PC00165;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC121835595|UniProtKB=A0ACM8FW83 A0ACM8FW83 LOC121835595 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120844733|UniProtKB=A0ACM8F0I5 A0ACM8F0I5 LOC120844733 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC115313281|UniProtKB=A0ACM8DSW9 A0ACM8DSW9 LOC115313281 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8052485|UniProtKB=A0ACM8DM35 A0ACM8DM35 LOC8052485 PTHR46599:SF8 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121837945|UniProtKB=A0ACM8G5I1 A0ACM8G5I1 LOC121837945 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8026224|UniProtKB=A0ACM8DHD4 A0ACM8DHD4 LOC8026224 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;ubiquitin-protein transferase activity#GO:0004842;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8035851|UniProtKB=A0ACM8DWU8 A0ACM8DWU8 LOC8035851 PTHR13586:SF0 SCD6 PROTEIN-RELATED TRAILER HITCH, ISOFORM H mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;P-body assembly#GO:0033962;cellular process#GO:0009987;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115309602|UniProtKB=A0ACM8F779 A0ACM8F779 LOC115309602 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8052621|UniProtKB=A0ACM8F3S8 A0ACM8F3S8 LOC8052621 PTHR15440:SF0 XRP2 PROTEIN PROTEIN XRP2 enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234 post-Golgi vesicle-mediated transport#GO:0006892;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cilium#GO:0005929 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8036711|UniProtKB=A0ACM8DND6 A0ACM8DND6 LOC8036711 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8036009|UniProtKB=A0ACM8E3N7 A0ACM8E3N7 LOC8036009 PTHR48178:SF1 PEROXISOME BIOGENESIS FACTOR 2 PEROXISOME BIOGENESIS PROTEIN 2 IXOSC|EnsemblGenome=LOC115310406|UniProtKB=A0ACM8DPP3 A0ACM8DPP3 LOC115310406 PTHR12224:SF0 BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121832953|UniProtKB=A0ACM8G7P1 A0ACM8G7P1 LOC121832953 PTHR14614:SF172 HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN PROTEIN-LYSINE N-METHYLTRANSFERASE EEF2KMT transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;protein-lysine N-methyltransferase activity#GO:0016279;lysine N-methyltransferase activity#GO:0016278 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115328036|UniProtKB=A0ACM8FMA4 A0ACM8FMA4 LOC115328036 PTHR45758:SF20 MITOFERRIN-1-RELATED MITOFERRIN-2 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;iron ion transmembrane transporter activity#GO:0005381 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transmembrane transport#GO:0034755;iron ion transport#GO:0006826;monoatomic ion transmembrane transport#GO:0034220;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;membrane#GO:0016020;organelle envelope#GO:0031967;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8035236|UniProtKB=A0ACM8DJS1 A0ACM8DJS1 EMC10 PTHR21397:SF6 CHROMATIN COMPLEXES SUBUNIT BAP18-RELATED ER MEMBRANE PROTEIN COMPLEX SUBUNIT 10 molecular carrier activity#GO:0140104;membrane insertase activity#GO:0032977;protein carrier activity#GO:0140597 localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;tail-anchored membrane protein insertion into ER membrane#GO:0071816;protein insertion into membrane#GO:0051205;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;cellular process#GO:0009987 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;EMC complex#GO:0072546;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8027947|UniProtKB=A0ACM8EAE1 A0ACM8EAE1 LOC8027947 PTHR20893:SF2 LD08641P LD08641P IXOSC|EnsemblGenome=LOC8043245|UniProtKB=A0ACM8E9E8 A0ACM8E9E8 LeuRS-m PTHR43740:SF3 LEUCYL-TRNA SYNTHETASE LEUCINE--TRNA LIGASE, MITOCHONDRIAL catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;translation#GO:0006412;mitochondrial gene expression#GO:0140053;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC115320977|UniProtKB=A0ACM8E0T5 A0ACM8E0T5 LOC115320977 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8033772|UniProtKB=A0ACM8DPL8 A0ACM8DPL8 LOC8033772 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8038995|UniProtKB=A0ACM8ES14 A0ACM8ES14 LOC8038995 PTHR10434:SF11 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;glycerolipid metabolic process#GO:0046486;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transferase#PC00220;acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8040916|UniProtKB=A0ACM8E030 A0ACM8E030 Pus7 PTHR13326:SF31 TRNA PSEUDOURIDINE SYNTHASE D PSEUDOURIDYLATE SYNTHASE 7 HOMOLOG intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;pseudouridine synthesis#GO:0001522;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;RNA modification#GO:0009451 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8023900|UniProtKB=A0ACM8DHR0 A0ACM8DHR0 LOC8023900 PTHR34174:SF1 HYDROLETHALUS SYNDROME PROTEIN 1 CENTRIOLAR AND CILIOGENESIS-ASSOCIATED PROTEIN HYLS1 organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component organization#GO:0016043;cilium assembly#GO:0060271;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;plasma membrane bounded cell projection organization#GO:0120036;cell projection organization#GO:0030030;cellular component assembly#GO:0022607 cilium#GO:0005929;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;non-motile cilium#GO:0097730;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;plasma membrane bounded cell projection#GO:0120025;intracellular membraneless organelle#GO:0043232;cell projection#GO:0042995;centriole#GO:0005814;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8028191|UniProtKB=A0ACM8E978 A0ACM8E978 LOC8028191 PTHR18444:SF9 UPF0538 FAMILY MEMBER UPF0538 PROTEIN C2ORF76 IXOSC|EnsemblGenome=LOC120840198|UniProtKB=A0ACM8ENC9 A0ACM8ENC9 LOC120840198 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular response to stimulus#GO:0051716;cellular process#GO:0009987;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8043850|UniProtKB=A0ACM8E1N8 A0ACM8E1N8 LOC8043850 PTHR43721:SF3 ELONGATION FACTOR TU-RELATED GTP-BINDING PROTEIN 2 translation factor activity#GO:0180051;translation elongation factor activity#GO:0003746 macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;translation#GO:0006412;translational elongation#GO:0006414;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC115310188|UniProtKB=A0ACM8DPF8 A0ACM8DPF8 PTHR13238:SF0 PROTEIN C21ORF59 CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 298 IXOSC|EnsemblGenome=LOC8031632|UniProtKB=A0ACM8G220 A0ACM8G220 LOC8031632 PTHR12322:SF129 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT PROTEIN DOUBLESEX RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;developmental process#GO:0032502;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;sex differentiation#GO:0007548;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;reproductive process#GO:0022414;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8040894|UniProtKB=A0ACM8FL76 A0ACM8FL76 LOC8040894 PTHR11941:SF27 ENOYL-COA HYDRATASE-RELATED ETHYLMALONYL-COA DECARBOXYLASE lyase activity#GO:0016829;carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824 catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;lipid oxidation#GO:0034440;fatty acid catabolic process#GO:0009062;oxoacid metabolic process#GO:0043436;monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid modification#GO:0030258;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 hydratase#PC00120;lyase#PC00144;metabolite interconversion enzyme#PC00262 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163 IXOSC|EnsemblGenome=LOC8033936|UniProtKB=A0ACM8EET5 A0ACM8EET5 Nhe3 PTHR10110:SF201 SODIUM/HYDROGEN EXCHANGER SODIUM_HYDROGEN EXCHANGER monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;metal cation:proton antiporter activity#GO:0051139;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297 sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;potassium ion transmembrane transport#GO:0071805;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;import into cell#GO:0098657;establishment of localization#GO:0051234;sodium ion transport#GO:0006814;intracellular monoatomic ion homeostasis#GO:0006873;homeostatic process#GO:0042592;metal ion transport#GO:0030001;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;regulation of intracellular pH#GO:0051453;regulation of pH#GO:0006885;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;recycling endosome#GO:0055037;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8037486|UniProtKB=A0ACM8DI56 A0ACM8DI56 RpS20 PTHR11700:SF8 30S RIBOSOMAL PROTEIN S10 FAMILY MEMBER SMALL RIBOSOMAL SUBUNIT PROTEIN US10 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121838059|UniProtKB=A0ACM8G6E1 A0ACM8G6E1 LOC121838059 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8043622|UniProtKB=A0ACM8DV60 A0ACM8DV60 eEF2 PTHR42908:SF10 TRANSLATION ELONGATION FACTOR-RELATED EUKARYOTIC TRANSLATION ELONGATION FACTOR 2 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;translation factor activity#GO:0180051;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational elongation#GO:0006414;metabolic process#GO:0008152;translation#GO:0006412 cytosol#GO:0005829;ribonucleoprotein complex#GO:1990904;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC115327638|UniProtKB=A0ACM8EJ88 A0ACM8EJ88 LOC115327638 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8052141|UniProtKB=A0ACM8G1V9 A0ACM8G1V9 LOC8052141 PTHR45636:SF43 PAIRED BOX PROTEIN PAX-6-RELATED-RELATED PAIRED BOX POX-NEURO PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;sensory organ development#GO:0007423;nervous system development#GO:0007399;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC121835653|UniProtKB=A0ACM8FWD1 A0ACM8FWD1 LOC121835653 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120839671|UniProtKB=A0ACM8ELR8 A0ACM8ELR8 LOC120839671 PTHR28668:SF1 TRANSMEMBRANE PROTEIN 234 TRANSMEMBRANE PROTEIN 234 IXOSC|EnsemblGenome=LOC120850591|UniProtKB=A0ACM8FR16 A0ACM8FR16 PTHR33198:SF22 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849022|UniProtKB=A0ACM8G3I9 A0ACM8G3I9 LOC120849022 PTHR24406:SF24 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN ZIPIC zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120850067|UniProtKB=A0ACM8F9C4 A0ACM8F9C4 LOC120850067 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8032986|UniProtKB=A0ACM8EEH0 A0ACM8EEH0 LOC8032986 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120841480|UniProtKB=A0ACM8ERP7 A0ACM8ERP7 LOC120841480 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120850459|UniProtKB=A0ACM8FA70 A0ACM8FA70 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120842715|UniProtKB=A0ACM8EUB1 A0ACM8EUB1 LOC120842715 PTHR46481:SF16 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 BED-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039141|UniProtKB=A0ACM8DWL5 A0ACM8DWL5 LOC8039141 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8031430|UniProtKB=A0ACM8E8M7 A0ACM8E8M7 LOC8031430 PTHR10410:SF39 EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED HISTONE H2A DEUBIQUITINASE MYSM1 ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;deubiquitinase activity#GO:0101005;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC120840332|UniProtKB=A0ACM8EP72 A0ACM8EP72 LOC120840332 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310655|UniProtKB=A0ACM8ELA0 A0ACM8ELA0 LOC115310655 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028285|UniProtKB=A0ACM8E5J5 A0ACM8E5J5 LOC8028285 PTHR45656:SF4 PROTEIN CBR-CLEC-78 COMPLEMENT COMPONENT RECEPTOR 1-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030685|UniProtKB=A0ACM8DZF8 A0ACM8DZF8 LOC8030685 PTHR45817:SF4 LYSYL OXIDASE-LIKE-RELATED LYSYL OXIDASE-LIKE-RELATED catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC120841353|UniProtKB=A0ACM8ESH2 A0ACM8ESH2 LOC120841353 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120837466|UniProtKB=A0ACM8EHF6 A0ACM8EHF6 LOC120837466 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120840408|UniProtKB=A0ACM8EPF1 A0ACM8EPF1 LOC120840408 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835072|UniProtKB=A0ACM8FRD2 A0ACM8FRD2 LOC121835072 PTHR10680:SF39 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 IXOSC|EnsemblGenome=LOC120840070|UniProtKB=A0ACM8END8 A0ACM8END8 LOC120840070 PTHR33776:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033538|UniProtKB=A0ACM8EPR4 A0ACM8EPR4 LOC8033538 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115314610|UniProtKB=A0ACM8ESF9 A0ACM8ESF9 LOC115314610 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8023235|UniProtKB=A0ACM8E619 A0ACM8E619 LOC8023235 PTHR14463:SF5 LIPASE MATURATION FACTOR LIPASE MATURATION FACTOR 2 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC121837429|UniProtKB=A0ACM8G380 A0ACM8G380 LOC121837429 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838398|UniProtKB=A0ACM8EKR8 A0ACM8EKR8 LOC120838398 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322015|UniProtKB=A0ACM8ETR2 A0ACM8ETR2 LOC115322015 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120842079|UniProtKB=A0ACM8ET11 A0ACM8ET11 LOC120842079 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115324840|UniProtKB=A0ACM8FYM1 A0ACM8FYM1 LOC115324840 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC121835865|UniProtKB=A0ACM8FWX7 A0ACM8FWX7 LOC121835865 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121834558|UniProtKB=A0ACM8FQ23 A0ACM8FQ23 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC115333097|UniProtKB=A0ACM8EF14 A0ACM8EF14 LOC115333097 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120849750|UniProtKB=A0ACM8F8N9 A0ACM8F8N9 mRpL43 PTHR21396:SF2 39S RIBOSOMAL PROTEIN L43 LARGE RIBOSOMAL SUBUNIT PROTEIN ML43 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120837385|UniProtKB=A0ACM8EH85 A0ACM8EH85 LOC120837385 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121045759|UniProtKB=A0ACM8FAW3 A0ACM8FAW3 LOC121045759 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028886|UniProtKB=A0ACM8DNR0 A0ACM8DNR0 LOC8028886 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8042861|UniProtKB=A0ACM8EHR8 A0ACM8EHR8 LOC8042861 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;purine-containing compound catabolic process#GO:0072523;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;phosphodiesterase#PC00185 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC8034049|UniProtKB=A0ACM8DZQ0 A0ACM8DZQ0 LOC8034049 PTHR24056:SF222 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE-LIKE 2 phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC115321868|UniProtKB=A0ACM8FAV5 A0ACM8FAV5 LOC115321868 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115332229|UniProtKB=A0ACM8ELM7 A0ACM8ELM7 LOC115332229 PTHR34008:SF2 REPETITIVE PROLINE-RICH CELL WALL PROTEIN 1 REPETITIVE PROLINE-RICH CELL WALL PROTEIN 1 IXOSC|EnsemblGenome=LOC8034058|UniProtKB=A0ACM8EFN1 A0ACM8EFN1 LOC8034058 PTHR46107:SF3 DUMPY: SHORTER THAN WILD-TYPE THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 1 disulfide oxidoreductase activity#GO:0015036;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8043233|UniProtKB=A0ACM8DSG1 A0ACM8DSG1 msl-2 PTHR16048:SF3 MSL2-RELATED E3 UBIQUITIN-PROTEIN LIGASE MSL2 ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234 IXOSC|EnsemblGenome=LOC8023872|UniProtKB=A0ACM8DHP6 A0ACM8DHP6 LOC8023872 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120850859|UniProtKB=A0ACM8FB83 A0ACM8FB83 LOC120850859 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331636|UniProtKB=A0ACM8FER9 A0ACM8FER9 LOC115331636 PTHR18966:SF602 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;transmembrane signaling receptor activity#GO:0004888;gated channel activity#GO:0022836;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;passive transmembrane transporter activity#GO:0022803;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276 cellular process#GO:0009987;synaptic signaling#GO:0099536;synaptic transmission, glutamatergic#GO:0035249;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell communication#GO:0007154;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;regulation of cell communication#GO:0010646;signaling#GO:0023052;modulation of chemical synaptic transmission#GO:0050804;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916 postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC8032748|UniProtKB=A0ACM8EAG0 A0ACM8EAG0 LOC8032748 PTHR23074:SF17 AAA DOMAIN-CONTAINING FIDGETIN-LIKE PROTEIN 1 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on a protein#GO:0140096;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887 microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC8034108|UniProtKB=A0ACM8DIY8 A0ACM8DIY8 LOC8034108 PTHR15396:SF1 RIBONUCLEASE P PROTEIN SUBUNIT P40 RIBONUCLEASE P PROTEIN SUBUNIT P40 endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;ribonuclease P activity#GO:0004526 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;tRNA processing#GO:0008033;metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;ribosomal small subunit biogenesis#GO:0042274;endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000447;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;maturation of 5.8S rRNA#GO:0000460;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000466;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 multimeric ribonuclease P complex#GO:0030681;ribonuclease MRP complex#GO:0000172;protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;catalytic complex#GO:1902494;endonuclease complex#GO:1905348;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031;endoribonuclease#PC00094 IXOSC|EnsemblGenome=LOC8051844|UniProtKB=A0ACM8DLW9 A0ACM8DLW9 CIAPIN1 PTHR13273:SF14 ANAMORSIN ANAMORSIN iron-sulfur cluster assembly#GO:0016226;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=ISCI008069|UniProtKB=Q4PM31 Q4PM31 PTHR11830:SF0 40S RIBOSOMAL PROTEIN S3A SMALL RIBOSOMAL SUBUNIT PROTEIN ES1 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;translation#GO:0006412 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120837624|UniProtKB=A0ACM8EHY1 A0ACM8EHY1 LOC120837624 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115318004|UniProtKB=A0ACM8DXJ8 A0ACM8DXJ8 LOC115318004 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120848037|UniProtKB=A0ACM8F5A2 A0ACM8F5A2 LOC120848037 PTHR42673:SF24 MALEYLACETOACETATE ISOMERASE MALEYLACETOACETATE ISOMERASE cis-trans isomerase activity#GO:0016859;isomerase activity#GO:0016853;transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 isomerase#PC00135 IXOSC|EnsemblGenome=LOC120837754|UniProtKB=A0ACM8G584 A0ACM8G584 LOC120837754 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120842928|UniProtKB=A0ACM8EUT5 A0ACM8EUT5 LOC120842928 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849084|UniProtKB=A0ACM8F730 A0ACM8F730 LOC120849084 PTHR23080:SF63 THAP DOMAIN PROTEIN DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030322|UniProtKB=A0ACM8DY39 A0ACM8DY39 LOC8030322 PTHR19411:SF0 PROTEIN BUD31-RELATED PROTEIN BUD31 HOMOLOG biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8028483|UniProtKB=A0ACM8EFY7 A0ACM8EFY7 LOC8028483 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120837697|UniProtKB=A0ACM8EI50 A0ACM8EI50 LOC120837697 PTHR24115:SF472 KINESIN-RELATED KINESIN-LIKE PROTEIN KIF3A protein binding#GO:0005515;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;cytoskeletal protein binding#GO:0008092;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;microtubule motor activity#GO:0003777;microtubule binding#GO:0008017;polypeptide conformation or assembly isomerase activity#GO:0120544;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;tubulin binding#GO:0015631;macromolecular conformation isomerase activity#GO:0120543 plasma membrane bounded cell projection assembly#GO:0120031;intracellular transport#GO:0046907;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;microtubule-based process#GO:0007017;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;axo-dendritic transport#GO:0008088;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component assembly#GO:0022607;cytoskeleton-dependent intracellular transport#GO:0030705;plasma membrane bounded cell projection organization#GO:0120036;organelle assembly#GO:0070925;axonal transport#GO:0098930;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641;anterograde axonal transport#GO:0008089;cilium organization#GO:0044782;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;protein-containing complex#GO:0032991;supramolecular polymer#GO:0099081;microtubule associated complex#GO:0005875;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226 microtubule or microtubule-binding cytoskeletal protein#PC00157;microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC8052059|UniProtKB=A0ACM8EDY9 A0ACM8EDY9 APC4 PTHR13260:SF0 ANAPHASE PROMOTING COMPLEX SUBUNIT 4 APC4 ANAPHASE-PROMOTING COMPLEX SUBUNIT 4 catabolic process#GO:0009056;protein modification by small protein conjugation#GO:0032446;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein K11-linked ubiquitination#GO:0070979;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein modification by small protein conjugation or removal#GO:0070647;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;organelle lumen#GO:0043233;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 IXOSC|EnsemblGenome=LOC121838463|UniProtKB=A0ACM8G833 A0ACM8G833 LOC121838463 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039605|UniProtKB=A0ACM8G4L6 A0ACM8G4L6 LOC8039605 PTHR16199:SF4 CONDENSIN-2 COMPLEX SUBUNIT G2 CONDENSIN-2 COMPLEX SUBUNIT G2 mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cellular component organization#GO:0016043;sister chromatid segregation#GO:0000819;nuclear chromosome segregation#GO:0098813;cell cycle#GO:0007049;organelle fission#GO:0048285;nuclear division#GO:0000280;cellular process#GO:0009987;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;chromosome organization#GO:0051276;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;condensin complex#GO:0000796 IXOSC|EnsemblGenome=LOC121837625|UniProtKB=A0ACM8G4C3 A0ACM8G4C3 LOC121837625 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120843230|UniProtKB=A0ACM8G8X9 A0ACM8G8X9 LOC120843230 PTHR33426:SF52 C2H2-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8050426|UniProtKB=A0ACM8G6X2 A0ACM8G6X2 LOC8050426 PTHR43394:SF1 ATP-DEPENDENT PERMEASE MDL1, MITOCHONDRIAL ABC TRANSPORTER B FAMILY MEMBER 4 IXOSC|EnsemblGenome=LOC120847519|UniProtKB=A0ACM8F424 A0ACM8F424 LOC120847519 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115326594|UniProtKB=A0ACM8F6J8 A0ACM8F6J8 LOC115326594 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032287|UniProtKB=A0ACM8DWR1 A0ACM8DWR1 LOC8032287 PTHR19964:SF92 MULTIPLE PDZ DOMAIN PROTEIN PATJ HOMOLOG scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115330936|UniProtKB=A0ACM8EU79 A0ACM8EU79 LOC115330936 PTHR24390:SF79 ZINC FINGER PROTEIN LD33778P transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115332117|UniProtKB=A0ACM8FVF2 A0ACM8FVF2 LOC115332117 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120850872|UniProtKB=A0ACM8FZ80 A0ACM8FZ80 LOC120850872 PTHR24256:SF576 TRYPTASE-RELATED IP10114P-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8053879|UniProtKB=A0ACM8E272 A0ACM8E272 ND-SGDH PTHR13178:SF0 NADH-UBIQUINONE OXIDOREDUCTASE SGDH SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 5, MITOCHONDRIAL catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8029042|UniProtKB=A0ACM8DML0 A0ACM8DML0 LOC8029042 PTHR11575:SF50 5'-NUCLEOTIDASE-RELATED 5'-NUCLEOTIDASE catalytic activity#GO:0003824;5'-nucleotidase activity#GO:0008253;hydrolase activity, acting on ester bonds#GO:0016788;nucleotidase activity#GO:0008252;phosphatase activity#GO:0016791;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;purine-containing compound catabolic process#GO:0072523;purine nucleoside monophosphate metabolic process#GO:0009126;nucleobase-containing small molecule metabolic process#GO:0055086;purine ribonucleotide metabolic process#GO:0009150;nucleotide catabolic process#GO:0009166;metabolic process#GO:0008152;nucleoside phosphate catabolic process#GO:1901292;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;nucleoside monophosphate metabolic process#GO:0009123;purine ribonucleoside monophosphate metabolic process#GO:0009167;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 Pyrimidine Metabolism#P02771>5'-Nucleotidase#P03131;Purine metabolism#P02769>5'-Nucleotidase#P03119 IXOSC|EnsemblGenome=LOC8024546|UniProtKB=A0ACM8EDP0 A0ACM8EDP0 CSN1b PTHR14145:SF2 26S PROTESOME SUBUNIT 6 COP9 SIGNALOSOME COMPLEX SUBUNIT 1 protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;macromolecule metabolic process#GO:0043170;regulation of biological quality#GO:0065008;protein stabilization#GO:0050821;protein modification process#GO:0036211;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of protein stability#GO:0031647;post-translational protein modification#GO:0043687;biological regulation#GO:0065007 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;COP9 signalosome#GO:0008180;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8035787|UniProtKB=A0ACM8DJV3 A0ACM8DJV3 LOC8035787 PTHR31107:SF2 APOPTOGENIC PROTEIN 1, MITOCHONDRIAL CYTOCHROME C OXIDASE ASSEMBLY FACTOR 8 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120844658|UniProtKB=A0ACM8EZC4 A0ACM8EZC4 LOC120844658 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120844893|UniProtKB=A0ACM8EZZ9 A0ACM8EZZ9 LOC120844893 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8042953|UniProtKB=A0ACM8EW59 A0ACM8EW59 LOC8042953 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8026159|UniProtKB=A0ACM8DW34 A0ACM8DW34 LOC8026159 PTHR13108:SF9 CONDENSIN COMPLEX SUBUNIT 2 CONDENSIN COMPLEX SUBUNIT 2 binding#GO:0005488;chromatin binding#GO:0003682 mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;chromosome segregation#GO:0007059;cellular process#GO:0009987;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;mitotic chromosome condensation#GO:0007076;chromosome condensation#GO:0030261;organelle fission#GO:0048285;nuclear division#GO:0000280;mitotic cell cycle#GO:0000278;mitotic nuclear division#GO:0140014;cell cycle process#GO:0022402;cell cycle#GO:0007049;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;condensin complex#GO:0000796;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694 IXOSC|EnsemblGenome=LOC8037011|UniProtKB=A0ACM8E7L9 A0ACM8E7L9 LOC8037011 PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 cellular process#GO:0009987;transport#GO:0006810;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 transporter#PC00227 IXOSC|EnsemblGenome=LOC8024820|UniProtKB=A0ACM8DWF9 A0ACM8DWF9 LOC8024820 PTHR10869:SF244 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-2 catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;catalytic activity, acting on a protein#GO:0140096;dioxygenase activity#GO:0051213 membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8026535|UniProtKB=A0ACM8DHW1 A0ACM8DHW1 LOC8026535 PTHR24073:SF1125 DRAB5-RELATED RAS-RELATED PROTEIN RAB-43 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;intracellular protein localization#GO:0008104;protein transport#GO:0015031;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC115327234|UniProtKB=A0ACM8FD15 A0ACM8FD15 LOC115327234 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 cell cycle#GO:0007049;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047 cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8041994|UniProtKB=A0ACM8F9H1 A0ACM8F9H1 LOC8041994 PTHR13817:SF166 TITIN MYOMESIN AND MYOSIN BINDING PROTEIN structural protein#PC00211 IXOSC|EnsemblGenome=LOC115315069|UniProtKB=A0ACM8DV43 A0ACM8DV43 LOC115315069 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120841327|UniProtKB=A0ACM8ESF7 A0ACM8ESF7 LOC120841327 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8041953|UniProtKB=A0ACM8E9G0 A0ACM8E9G0 LOC8041953 PTHR12322:SF129 DOUBLESEX AND MAB-3 RELATED TRANSCRIPTION FACTOR DMRT PROTEIN DOUBLESEX sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biological process#GO:0050789;developmental process involved in reproduction#GO:0003006;reproductive process#GO:0022414;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;sex differentiation#GO:0007548;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121834301|UniProtKB=A0ACM8FQ36 A0ACM8FQ36 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037296|UniProtKB=A0ACM8DK41 A0ACM8DK41 LOC8037296 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115315675|UniProtKB=A0ACM8DVQ0 A0ACM8DVQ0 LOC115315675 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035463|UniProtKB=A0ACM8ELT4 A0ACM8ELT4 LOC8035463 PTHR19282:SF431 TETRASPANIN TETRASPANIN 26A, ISOFORM B cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115331523|UniProtKB=A0ACM8EC28 A0ACM8EC28 LOC115331523 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8041780|UniProtKB=A0ACM8DKS4 A0ACM8DKS4 LOC8041780 PTHR44054:SF2 SYNAPTIC VESICLE MEMBRANE PROTEIN VAT-1 HOMOLOG-LIKE NADPH-DEPENDENT QUINONE OXIDOREDUCTASE VAT1L-RELATED Huntington disease#P00029>PIG3#G01535 IXOSC|EnsemblGenome=LOC8052761|UniProtKB=A0ACM8DM25 A0ACM8DM25 LOC8052761 PTHR43213:SF5 BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;nucleoside triphosphate diphosphatase activity#GO:0047429;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120850807|UniProtKB=A0ACM8G8K7 A0ACM8G8K7 LOC120850807 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043606|UniProtKB=A0ACM8E958 A0ACM8E958 LOC8043606 PTHR10742:SF410 FLAVIN MONOAMINE OXIDASE LYSINE-SPECIFIC HISTONE DEMETHYLASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidase#PC00175 IXOSC|EnsemblGenome=LOC8041616|UniProtKB=A0ACM8FUS7 A0ACM8FUS7 LOC8041616 PTHR11690:SF248 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL monoatomic cation channel activity#GO:0005261;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;ligand-gated monoatomic cation channel activity#GO:0099094;sodium channel activity#GO:0005272;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836 transport#GO:0006810;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC115318000|UniProtKB=A0ACM8ESN3 A0ACM8ESN3 LOC115318000 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;metabolic process#GO:0008152 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121837511|UniProtKB=A0ACM8G3S1 A0ACM8G3S1 LOC121837511 PTHR10825:SF75 RING FINGER DOMAIN-CONTAINING, POLYCOMB GROUP COMPONENT POLYCOMB GROUP PROTEIN PSC binding#GO:0005488;chromatin binding#GO:0003682 regulation of DNA-templated transcription#GO:0006355;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605 PcG protein complex#GO:0031519;nucleus#GO:0005634;protein-containing complex#GO:0032991;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;PRC1 complex#GO:0035102;intracellular protein-containing complex#GO:0140535;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ubiquitin ligase complex#GO:0000151;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC120843638|UniProtKB=A0ACM8EWK8 A0ACM8EWK8 LOC120843638 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115311332|UniProtKB=A0ACM8EPD0 A0ACM8EPD0 LOC115311332 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030485|UniProtKB=A0ACM8FIQ9 A0ACM8FIQ9 PTHR24351:SF110 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;TOR signaling#GO:0031929;TORC1 signaling#GO:0038202;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protein modifying enzyme#PC00260 Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>P90 RSK#P00888;Interleukin signaling pathway#P00036>p90RSK#P00964;PDGF signaling pathway#P00047>p90RSK#P01142 IXOSC|EnsemblGenome=LOC121046382|UniProtKB=A0ACM8FDR9 A0ACM8FDR9 LOC121046382 PTHR24023:SF1112 COLLAGEN ALPHA COLLAGEN ALPHA-2(IX) CHAIN PRECURSOR-RELATED extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 cellular process#GO:0009987;cellular component organization#GO:0016043;extracellular structure organization#GO:0043062;external encapsulating structure organization#GO:0045229;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 extracellular matrix structural protein#PC00103;extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC8024489|UniProtKB=A0ACM8FUE0 A0ACM8FUE0 LOC8024489 PTHR31139:SF6 ECTOPIC P GRANULES PROTEIN 5 HOMOLOG PROTEIN LIMB EXPRESSION 1 HOMOLOG cytoskeleton organization#GO:0007010;cellular component organization or biogenesis#GO:0071840;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115322017|UniProtKB=A0ACM8EXE8 A0ACM8EXE8 LOC115322017 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046443|UniProtKB=A0ACM8FCS9 A0ACM8FCS9 LOC121046443 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8029146|UniProtKB=A0ACM8E021 A0ACM8E021 LOC8029146 PTHR12756:SF11 CYTOSOLIC CARBOXYPEPTIDASE CYTOSOLIC CARBOXYPEPTIDASE 1 binding#GO:0005488;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;protein binding#GO:0005515;carboxypeptidase activity#GO:0004180;catalytic activity#GO:0003824;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;metalloexopeptidase activity#GO:0008235;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8052921|UniProtKB=A0ACM8DSV9 A0ACM8DSV9 LOC8052921 PTHR24252:SF32 ACROSIN-RELATED SERINE PROTEASE 33 hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8052398|UniProtKB=A0ACM8EEU9 A0ACM8EEU9 LOC8052398 PTHR10816:SF15 MYELIN TRANSCRIPTION FACTOR 1-RELATED MYELIN TRANSCRIPTION FACTOR 1-LIKE PROTEIN gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121046434|UniProtKB=A0ACM8FCR9 A0ACM8FCR9 LOC121046434 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052424|UniProtKB=A0ACM8EG25 A0ACM8EG25 LOC8052424 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC120849092|UniProtKB=A0ACM8F804 A0ACM8F804 LOC120849092 PTHR19818:SF173 ZINC FINGER PROTEIN ZIC AND GLI SUBFAMILY NOT NAMED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115326063|UniProtKB=A0ACM8F4T3 A0ACM8F4T3 LOC115326063 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034784|UniProtKB=A0ACM8E6S1 A0ACM8E6S1 Klp98A PTHR47117:SF6 STAR-RELATED LIPID TRANSFER PROTEIN 9 MICROTUBULE-ASSOCIATED PROTEIN FUTSCH-LIKE IXOSC|EnsemblGenome=LOC8043339|UniProtKB=A0ACM8DL52 A0ACM8DL52 LOC8043339 PTHR23503:SF8 SOLUTE CARRIER FAMILY 2 FACILITATED GLUCOSE TRANSPORTER PROTEIN 1 carbohydrate transmembrane transporter activity#GO:0015144;sugar transmembrane transporter activity#GO:0051119;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;carbohydrate transmembrane transport#GO:0034219;carbohydrate transport#GO:0008643;transport#GO:0006810;cellular process#GO:0009987 membrane#GO:0016020;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120849464|UniProtKB=A0ACM8F6V3 A0ACM8F6V3 LOC120849464 PTHR10202:SF27 PRESENILIN PRESENILIN HOMOLOG hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;homeostatic process#GO:0042592;signaling#GO:0023052;proteolysis#GO:0006508;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;cell communication#GO:0007154;protein metabolic process#GO:0019538;monoatomic ion homeostasis#GO:0050801;membrane protein proteolysis#GO:0033619;signal transduction#GO:0007165;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein processing#GO:0016485;membrane protein ectodomain proteolysis#GO:0006509;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;biological regulation#GO:0065007;metabolic process#GO:0008152;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;cell surface receptor signaling pathway#GO:0007166;macromolecule metabolic process#GO:0043170;Notch signaling pathway#GO:0007219 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane#GO:0016020;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;catalytic complex#GO:1902494 protease#PC00190;aspartic protease#PC00053 Alzheimer disease-amyloid secretase pathway#P00003>Presenilin N-terminal fragment#P00088;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin C-terminal fragment#P00102;Alzheimer disease-presenilin pathway#P00004>Presenilin N-terminal fragment#P00140;Alzheimer disease-amyloid secretase pathway#P00003>Presenilin#P00098;Alzheimer disease-presenilin pathway#P00004>Presenilin#P00129;Alzheimer disease-presenilin pathway#P00004>Presenilin C-terminal fragment#P00155;Notch signaling pathway#P00045>Presenilin#P01110 IXOSC|EnsemblGenome=LOC8036118|UniProtKB=A0ACM8G3A1 A0ACM8G3A1 LOC8036118 PTHR45787:SF13 LD11652P LD11652P transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of RNA metabolic process#GO:0051252;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8031194|UniProtKB=A0ACM8DVK8 A0ACM8DVK8 LOC8031194 PTHR12776:SF1 KAZRIN-RELATED KAZRIN IXOSC|EnsemblGenome=LOC8039711|UniProtKB=A0ACM8DYC8 A0ACM8DYC8 Droj2 PTHR43888:SF10 DNAJ-LIKE-2, ISOFORM A-RELATED DNAJ-LIKE-2, ISOFORM A ATPase activator activity#GO:0001671;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772 protein metabolic process#GO:0019538;protein refolding#GO:0042026;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;cellular response to heat#GO:0034605;response to heat#GO:0009408;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8043696|UniProtKB=A0ACM8DGU5 A0ACM8DGU5 LOC8043696 PTHR16523:SF6 PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN PEST PROTEOLYTIC SIGNAL-CONTAINING NUCLEAR PROTEIN protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8025573|UniProtKB=A0ACM8DMW3 A0ACM8DMW3 LOC8025573 PTHR45781:SF1 AGAP000281-PA HMG BOX DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120839888|UniProtKB=A0ACM8EMC9 A0ACM8EMC9 LOC120839888 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844380|UniProtKB=A0ACM8E939 A0ACM8E939 LOC8038260 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle membrane contact site#GO:0044232 IXOSC|EnsemblGenome=LOC115325296|UniProtKB=A0ACM8ERP6 A0ACM8ERP6 LOC115325296 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8025568|UniProtKB=A0ACM8E6N7 A0ACM8E6N7 LOC8025568 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8029290|UniProtKB=A0ACM8DNF9 A0ACM8DNF9 LOC8029290 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 transport#GO:0006810;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC120839884|UniProtKB=A0ACM8FNZ3 A0ACM8FNZ3 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120841963|UniProtKB=A0ACM8ESR8 A0ACM8ESR8 LOC120841963 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115327067|UniProtKB=A0ACM8EMY7 A0ACM8EMY7 LOC115327067 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC115329877|UniProtKB=A0ACM8EA90 A0ACM8EA90 CCDC53 PTHR13015:SF0 PROTEIN AD-016-RELATED WASH COMPLEX SUBUNIT 3 protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cellular component organization#GO:0016043;export from cell#GO:0140352;actin cytoskeleton organization#GO:0030036;actin filament polymerization#GO:0030041;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;secretion by cell#GO:0032940;secretion#GO:0046903;localization#GO:0051179;actin polymerization or depolymerization#GO:0008154;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;vesicle-mediated transport#GO:0016192;cellular component assembly#GO:0022607;transport#GO:0006810;protein-containing complex organization#GO:0043933;exocytosis#GO:0006887;actin filament organization#GO:0007015;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8052992|UniProtKB=A0ACM8DYW2 A0ACM8DYW2 LOC8052992 PTHR12563:SF17 GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;acetyltransferase activity#GO:0016407;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;metabolic process#GO:0008152 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;peroxisomal membrane#GO:0005778;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;microbody#GO:0042579 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120837098|UniProtKB=A0ACM8EGL2 A0ACM8EGL2 LOC120837098 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8032842|UniProtKB=A0ACM8G0W6 A0ACM8G0W6 LOC8032842 PTHR11412:SF166 MACROGLOBULIN / COMPLEMENT OPHIOPHAGUS VENOM FACTOR-LIKE chemokine activity#GO:0008009;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;signaling receptor binding#GO:0005102;binding#GO:0005488;cytokine receptor binding#GO:0005126;molecular function activator activity#GO:0140677;protein binding#GO:0005515;chemokine receptor binding#GO:0042379 response to stimulus#GO:0050896;defense response to other organism#GO:0098542;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to other organism#GO:0051707;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;immune response#GO:0006955;defense response to symbiont#GO:0140546;innate immune response#GO:0045087;response to external stimulus#GO:0009605;defense response#GO:0006952;immune system process#GO:0002376 catalytic complex#GO:1902494;extracellular protein-containing complex#GO:0140392;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8030779|UniProtKB=A0ACM8F758 A0ACM8F758 Wdr37 PTHR19855:SF12 WD40 REPEAT PROTEIN 12, 37 WD REPEAT-CONTAINING PROTEIN 37 IXOSC|EnsemblGenome=LOC8036976|UniProtKB=A0ACM8FP78 A0ACM8FP78 PTHR35252:SF1 RETINITIS PIGMENTOSA 9 PROTEIN RETINITIS PIGMENTOSA 9 PROTEIN IXOSC|EnsemblGenome=LOC120838320|UniProtKB=A0ACM8G8R7 A0ACM8G8R7 LOC120838320 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8029896|UniProtKB=A0ACM8EI24 A0ACM8EI24 LOC8029896 PTHR20544:SF0 CENTROSOMAL PROTEIN CEP135 CENTROSOMAL PROTEIN CEP135 IXOSC|EnsemblGenome=LOC8033749|UniProtKB=A0ACM8E458 A0ACM8E458 LOC8033749 PTHR12232:SF15 SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH PROTEIN HOMOLOG cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8052053|UniProtKB=A0ACM8FIZ4 A0ACM8FIZ4 LOC8052053 PTHR12231:SF275 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631 cell adhesion#GO:0007155;cellular process#GO:0009987;cell-cell adhesion#GO:0098609 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cell junction#GO:0030054 cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8025836|UniProtKB=A0ACM8FS32 A0ACM8FS32 LOC8025836 PTHR10083:SF390 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED PAPILIN peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;serine-type endopeptidase inhibitor activity#GO:0004867;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115314392|UniProtKB=A0ACM8F796 A0ACM8F796 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC120841893|UniProtKB=A0ACM8FUA0 A0ACM8FUA0 LOC120841893 PTHR15261:SF4 THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING THROMBOSPONDIN-TYPE LAMININ G DOMAIN AND EAR REPEAT-CONTAINING PROTEIN cell communication#GO:0007154;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8052543|UniProtKB=A0ACM8DNG4 A0ACM8DNG4 LOC8052543 PTHR19432:SF35 SUGAR TRANSPORTER SOLUTE CARRIER FAMILY 45 MEMBER 3 ISOFORM X1 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8043060|UniProtKB=A0ACM8DL24 A0ACM8DL24 LOC8043060 PTHR23105:SF54 RIBOSOMAL PROTEIN L7AE FAMILY MEMBER H_ACA RIBONUCLEOPROTEIN COMPLEX SUBUNIT 2 nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515;binding#GO:0005488;RNA binding#GO:0003723 ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;rRNA modification#GO:0000154;pseudouridine synthesis#GO:0001522;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073;rRNA processing#GO:0006364;ribosome biogenesis#GO:0042254;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;snRNA processing#GO:0016180;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;sno(s)RNA-containing ribonucleoprotein complex#GO:0005732;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8043389|UniProtKB=A0ACM8FM55 A0ACM8FM55 LOC8043389 PTHR45700:SF9 UBIQUITIN-PROTEIN LIGASE E3C HECT-TYPE E3 UBIQUITIN TRANSFERASE protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120837213|UniProtKB=A0ACM8FDL7 A0ACM8FDL7 LOC120837213 PTHR48616:SF2 H15 DOMAIN-CONTAINING PROTEIN H15 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023262|UniProtKB=A0ACM8F404 A0ACM8F404 LOC8023262 PTHR10579:SF178 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-LIKE ion channel#PC00133 IXOSC|EnsemblGenome=LOC115325139|UniProtKB=A0ACM8EGI4 A0ACM8EGI4 LOC115325139 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324942|UniProtKB=A0ACM8E4F0 A0ACM8E4F0 LOC115324942 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8035609|UniProtKB=A0ACM8F2A9 A0ACM8F2A9 LOC8035609 PTHR12916:SF15 CYTOCHROME C OXIDASE POLYPEPTIDE VIC-2 UNINFLATABLE, ISOFORM C signaling receptor binding#GO:0005102;binding#GO:0005488;protein binding#GO:0005515 cell surface receptor signaling pathway#GO:0007166;Notch signaling pathway#GO:0007219;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC120838379|UniProtKB=A0ACM8EJT7 A0ACM8EJT7 LOC120838379 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC121837168|UniProtKB=A0ACM8G270 A0ACM8G270 LOC121837168 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8030476|UniProtKB=A0ACM8FLN9 A0ACM8FLN9 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115321069|UniProtKB=A0ACM8EQH3 A0ACM8EQH3 LOC115321069 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326264|UniProtKB=A0ACM8EFN6 A0ACM8EFN6 LOC115326264 PTHR12872:SF5 ALPHA-N-ACETYLGLUCOSAMINIDASE ALPHA-N-ACETYLGLUCOSAMINIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteoglycan metabolic process#GO:0006029 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121836695|UniProtKB=A0ACM8G0M2 A0ACM8G0M2 LOC8033214 PTHR13107:SF0 N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT N(6)-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT METTL14 mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular process#GO:0009987;mRNA modification#GO:0016556;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;nucleobase-containing compound metabolic process#GO:0006139;mRNA metabolic process#GO:0016071;RNA modification#GO:0009451;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;methyltransferase complex#GO:0034708;nucleus#GO:0005634 RNA processing factor#PC00147;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121836173|UniProtKB=A0ACM8FX81 A0ACM8FX81 LOC121836173 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121047204|UniProtKB=A0ACM8FFR4 A0ACM8FFR4 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841573|UniProtKB=A0ACM8ERY0 A0ACM8ERY0 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;peroxisome#GO:0005777;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121837308|UniProtKB=A0ACM8G459 A0ACM8G459 LOC121837308 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121832972|UniProtKB=A0ACM8FJA2 A0ACM8FJA2 LOC121832972 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120836931|UniProtKB=A0ACM8EG30 A0ACM8EG30 LOC120836931 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115319409|UniProtKB=A0ACM8DZR5 A0ACM8DZR5 LOC115319409 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8037015|UniProtKB=A0ACM8G1G8 A0ACM8G1G8 eIF2Bdelta PTHR10233:SF14 TRANSLATION INITIATION FACTOR EIF-2B TRANSLATION INITIATION FACTOR EIF2B SUBUNIT DELTA translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translational initiation#GO:0006413;translation#GO:0006412;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;guanyl-nucleotide exchange factor complex#GO:0032045 translation initiation factor#PC00224;translation factor#PC00223 IXOSC|EnsemblGenome=LOC8024014|UniProtKB=A0ACM8DHU7 A0ACM8DHU7 LOC8024014 PTHR46358:SF1 TONSOKU-LIKE PROTEIN TONSOKU-LIKE PROTEIN DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA recombination#GO:0006310;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;replication fork processing#GO:0031297;cellular process#GO:0009987;response to stress#GO:0006950 membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8034650|UniProtKB=A0ACM8DJJ1 A0ACM8DJJ1 LOC8034650 PTHR47522:SF2 SALVADOR FAMILY WW DOMAIN-CONTAINING PROTEIN 1 PROTEIN SALVADOR HOMOLOG 1 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of cell population proliferation#GO:0042127;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;negative regulation of cellular process#GO:0048523;positive regulation of apoptotic process#GO:0043065;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of cell population proliferation#GO:0008285;biological regulation#GO:0065007;hippo signaling#GO:0035329 cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8043624|UniProtKB=A0ACM8FD99 A0ACM8FD99 LOC8043624 PTHR14659:SF1 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 ALPHA- AND GAMMA-ADAPTIN-BINDING PROTEIN P34 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8023332|UniProtKB=A0ACM8DGT6 A0ACM8DGT6 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;peptidase activity#GO:0008233;exopeptidase activity#GO:0008238;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule catabolic process#GO:0044282;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115309841|UniProtKB=A0ACM8FX90 A0ACM8FX90 LOC115309841 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8037225|UniProtKB=A0ACM8EA76 A0ACM8EA76 Ubr1 PTHR21497:SF24 UBIQUITIN LIGASE E3 ALPHA-RELATED E3 UBIQUITIN-PROTEIN LIGASE UBR1 ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;catalytic activity#GO:0003824;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein modification by small protein conjugation or removal#GO:0070647;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;cellular process#GO:0009987 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;catalytic complex#GO:1902494;transferase complex#GO:1990234;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120837503|UniProtKB=A0ACM8EI98 A0ACM8EI98 LOC120837503 PTHR37162:SF14 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZMYM1-LIKE RNASE-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035214|UniProtKB=A0ACM8DVT0 A0ACM8DVT0 LOC8035214 PTHR11610:SF204 LIPASE PHOSPHOLIPASE A1 1-LIKE PROTEIN catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 hydrolase#PC00121;lipase#PC00143;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120842226|UniProtKB=A0ACM8FQD9 A0ACM8FQD9 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318790|UniProtKB=A0ACM8DYW9 A0ACM8DYW9 LOC115318790 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120844228|UniProtKB=A0ACM8EXU9 A0ACM8EXU9 LOC120844228 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;symporter activity#GO:0015293;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC121833780|UniProtKB=A0ACM8FNU9 A0ACM8FNU9 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838021|UniProtKB=A0ACM8G787 A0ACM8G787 LOC121838021 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120837402|UniProtKB=A0ACM8EHY5 A0ACM8EHY5 LOC120837402 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035190|UniProtKB=A0ACM8DZK8 A0ACM8DZK8 PI31 PTHR13266:SF1 PROTEASOME INHIBITOR PROTEASOME INHIBITOR PI31 SUBUNIT biological regulation#GO:0065007;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of protein catabolic process#GO:0042177;negative regulation of macromolecule metabolic process#GO:0010605;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of catabolic process#GO:0009894;negative regulation of cellular process#GO:0048523;negative regulation of protein metabolic process#GO:0051248;negative regulation of metabolic process#GO:0009892;negative regulation of proteasomal protein catabolic process#GO:1901799;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of protein catabolic process#GO:0042176;negative regulation of catabolic process#GO:0009895 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8033771|UniProtKB=A0ACM8F6R9 A0ACM8F6R9 wds PTHR22847:SF751 WD40 REPEAT PROTEIN WD REPEAT DOMAIN 5B chromatin-protein adaptor activity#GO:0140463;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;histone reader activity#GO:0140566 positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;transcription by RNA polymerase II#GO:0006366;positive regulation of gene expression#GO:0010628;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;transcription initiation at RNA polymerase II promoter#GO:0006367;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription initiation-coupled chromatin remodeling#GO:0045815;cellular component organization or biogenesis#GO:0071840;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;chromatin remodeling#GO:0006338;regulation of transcription by RNA polymerase II#GO:0006357;DNA-templated transcription initiation#GO:0006352;nucleic acid biosynthetic process#GO:0141187;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070 nuclear protein-containing complex#GO:0140513;Set1C/COMPASS complex#GO:0048188;membraneless organelle#GO:0043228;histone acetyltransferase complex#GO:0000123;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;histone methyltransferase complex#GO:0035097;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;chromatin#GO:0000785;nucleus#GO:0005634;NSL complex#GO:0044545;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;protein acetyltransferase complex#GO:0031248;methyltransferase complex#GO:0034708;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC120840361|UniProtKB=A0ACM8ENY2 A0ACM8ENY2 LOC120840361 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326339|UniProtKB=A0ACM8F6C8 A0ACM8F6C8 LOC115326339 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121835068|UniProtKB=A0ACM8FSS3 A0ACM8FSS3 LOC121835068 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115309448|UniProtKB=A0ACM8ETA4 A0ACM8ETA4 LOC115309448 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8028948|UniProtKB=A0ACM8FZM7 A0ACM8FZM7 LOC8028948 PTHR21446:SF12 DUF3504 DOMAIN-CONTAINING PROTEIN POTASSIUM CHANNEL TETRAMERIZATION DOMAIN CONTAINING 1 IXOSC|EnsemblGenome=LOC8041439|UniProtKB=A0ACM8E518 A0ACM8E518 LOC8041439 PTHR19302:SF13 GAMMA TUBULIN COMPLEX PROTEIN GAMMA-TUBULIN COMPLEX COMPONENT 2 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 sexual reproduction#GO:0019953;organelle assembly#GO:0070925;supramolecular fiber organization#GO:0097435;microtubule cytoskeleton organization#GO:0000226;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;cell cycle process#GO:0022402;microtubule nucleation#GO:0007020;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;reproductive process#GO:0022414;mitotic cell cycle#GO:0000278;cytoplasmic microtubule organization#GO:0031122;chromosome segregation#GO:0007059;meiotic cell cycle#GO:0051321;microtubule polymerization#GO:0046785;microtubule-based process#GO:0007017;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;microtubule polymerization or depolymerization#GO:0031109;spindle assembly#GO:0051225;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630 cytoskeletal protein#PC00085;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC121835513|UniProtKB=A0ACM8FUF3 A0ACM8FUF3 LOC121835513 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028547|UniProtKB=A0ACM8DGN5 A0ACM8DGN5 Ssu72 PTHR20383:SF9 RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE SSU72 protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;RNA 3'-end processing#GO:0031123;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;DNA-templated transcription termination#GO:0006353;mRNA processing#GO:0006397;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;mRNA cleavage factor complex#GO:0005849;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8040256|UniProtKB=A0ACM8DKJ8 A0ACM8DKJ8 LOC8040256 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8037103|UniProtKB=A0ACM8E9Q8 A0ACM8E9Q8 LOC8037103 PTHR15435:SF3 KICSTOR COMPLEX PROTEIN KAPTIN SOCS BOX DOMAIN-CONTAINING PROTEIN actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 IXOSC|EnsemblGenome=LOC120837719|UniProtKB=A0ACM8EIT3 A0ACM8EIT3 LOC120837719 PTHR11923:SF51 SCAVENGER RECEPTOR CLASS B TYPE-1 SR-B1 FI02050P-RELATED cargo receptor activity#GO:0038024 cellular anatomical structure#GO:0110165;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC121835355|UniProtKB=A0ACM8FST2 A0ACM8FST2 LOC121835355 PTHR23346:SF19 TRANSLATIONAL ACTIVATOR GCN1-RELATED PROTEASOME ADAPTER AND SCAFFOLD PROTEIN ECM29 response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;catabolic process#GO:0009056;response to stimulus#GO:0050896;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121837930|UniProtKB=A0ACM8G5E7 A0ACM8G5E7 LOC121837930 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8029794|UniProtKB=A0ACM8DXB4 A0ACM8DXB4 LOC8029794 PTHR19376:SF37 DNA-DIRECTED RNA POLYMERASE DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB1 DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;termination of RNA polymerase II transcription#GO:0006369;transcription by RNA polymerase II#GO:0006366;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;RNA polymerase II, core complex#GO:0005665;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;RNA polymerase II, holoenzyme#GO:0016591;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;protein-containing complex#GO:0032991;nucleus#GO:0005634;RNA polymerase complex#GO:0030880;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234 RNA metabolism protein#PC00031;DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC115320392|UniProtKB=A0ACM8E0R1 A0ACM8E0R1 LOC115320392 PTHR15272:SF0 CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A CAF-1 SUBUNIT A CHROMATIN ASSEMBLY FACTOR 1 SUBUNIT A protein carrier activity#GO:0140597;molecular carrier activity#GO:0140104 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;chromatin remodeling#GO:0006338;cellular component assembly#GO:0022607;protein-containing complex organization#GO:0043933;nucleosome organization#GO:0034728;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115315593|UniProtKB=A0ACM8DVF1 A0ACM8DVF1 LOC115315593 PTHR24394:SF67 ZINC FINGER PROTEIN MYONEURIN DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115323818|UniProtKB=A0ACM8E410 A0ACM8E410 LOC115323818 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320057|UniProtKB=A0ACM8E0L5 A0ACM8E0L5 CaBP1 PTHR45815:SF3 PROTEIN DISULFIDE-ISOMERASE A6 PROTEIN DISULFIDE-ISOMERASE A6 oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;protein-disulfide reductase activity#GO:0015035 response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;response to stress#GO:0006950 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115319907|UniProtKB=A0ACM8E0C3 A0ACM8E0C3 LOC115319907 PTHR13029:SF18 FAMILY NOT NAMED MYELIN REGULATORY FACTOR HOMOLOG 1 DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 metabolic process#GO:0008152;positive regulation of macromolecule metabolic process#GO:0010604;protein maturation#GO:0051604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;proteolysis#GO:0006508;regulation of biological process#GO:0050789;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;biosynthetic process#GO:0009058;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;protein metabolic process#GO:0019538;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;membrane#GO:0016020;nucleus#GO:0005634;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8053379|UniProtKB=A0ACM8DU72 A0ACM8DU72 mRpL53 PTHR33618:SF1 39S RIBOSOMAL PROTEIN L53, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML53 ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120837831|UniProtKB=A0ACM8FN62 A0ACM8FN62 spir PTHR21345:SF3 SPIRE PROTEIN SPIRE binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cellular localization#GO:0051641;spindle localization#GO:0051653;cytoskeleton-dependent cytokinesis#GO:0061640;nuclear division#GO:0000280;cytokinesis#GO:0000910;cytokinetic process#GO:0032506;establishment of organelle localization#GO:0051656;gamete generation#GO:0007276;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;meiotic cell cycle#GO:0051321;Golgi vesicle transport#GO:0048193;membrane invagination#GO:0010324;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle fission#GO:0048285;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;multicellular organismal reproductive process#GO:0048609;supramolecular fiber organization#GO:0097435;organelle localization#GO:0051640;actin filament-based process#GO:0030029;sexual reproduction#GO:0019953;actin cytoskeleton organization#GO:0030036;reproductive process#GO:0022414;cell cycle#GO:0007049;cell division#GO:0051301;meiotic nuclear division#GO:0140013;establishment of localization#GO:0051234;actin filament organization#GO:0007015;intracellular transport#GO:0046907;transport#GO:0006810;membrane organization#GO:0061024;establishment of spindle localization#GO:0051293 intracellular vesicle#GO:0097708;vesicle#GO:0031982;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;organelle membrane#GO:0031090 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8043885|UniProtKB=A0ACM8DMQ6 A0ACM8DMQ6 LOC8043885 PTHR23238:SF26 RNA BINDING PROTEIN GH13594P-RELATED transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;RNA binding#GO:0003723 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8027352|UniProtKB=A0ACM8FJV5 A0ACM8FJV5 LOC8027352 PTHR10827:SF52 RETICULOCALBIN RETICULOCALBIN-3 binding#GO:0005488;small molecule binding#GO:0036094;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 calcium-binding protein#PC00060;calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8034256|UniProtKB=A0ACM8EDQ0 A0ACM8EDQ0 LOC8034256 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120848447|UniProtKB=A0ACM8F622 A0ACM8F622 LOC120848447 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322937|UniProtKB=A0ACM8E395 A0ACM8E395 LOC115322937 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;biological regulation#GO:0065007;regulation of immune system process#GO:0002682 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8039891|UniProtKB=A0ACM8DV45 A0ACM8DV45 PTHR23270:SF10 PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5 PROTEIN RRP5 HOMOLOG U3 snoRNA binding#GO:0034511;RNA binding#GO:0003723;binding#GO:0005488;snoRNA binding#GO:0030515;nucleic acid binding#GO:0003676 ribosomal small subunit biogenesis#GO:0042274;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000480;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8036276|UniProtKB=A0ACM8EW57 A0ACM8EW57 LOC8036276 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096 carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8041009|UniProtKB=A0ACM8ENA5 A0ACM8ENA5 LOC8041009 PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED IXOSC|EnsemblGenome=LOC8053026|UniProtKB=A0ACM8DQY2 A0ACM8DQY2 LOC8053026 PTHR43290:SF4 MEVALONATE KINASE MEVALONATE KINASE phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 organophosphate biosynthetic process#GO:0090407;isoprenoid metabolic process#GO:0006720;acetyl-CoA metabolic process#GO:0006084;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;secondary alcohol biosynthetic process#GO:1902653;steroid biosynthetic process#GO:0006694;sterol metabolic process#GO:0016125;acyl-CoA metabolic process#GO:0006637;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;cholesterol metabolic process#GO:0008203;lipid biosynthetic process#GO:0008610;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;isoprenoid biosynthetic process#GO:0008299;small molecule metabolic process#GO:0044281;secondary alcohol metabolic process#GO:1902652;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;cholesterol biosynthetic process#GO:0006695;steroid metabolic process#GO:0008202;sterol biosynthetic process#GO:0016126;sulfur compound metabolic process#GO:0006790;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 carbohydrate kinase#PC00065 Cholesterol biosynthesis#P00014>Mevalonate kinase#P00492 IXOSC|EnsemblGenome=LOC120841008|UniProtKB=A0ACM8FEU0 A0ACM8FEU0 LOC120841008 PTHR23080:SF154 THAP DOMAIN PROTEIN CATHELICIDIN-LIKE ANTIMICROBIAL PROTEIN, ISOFORM A IXOSC|EnsemblGenome=LOC8040603|UniProtKB=A0ACM8ERD2 A0ACM8ERD2 LOC8040603 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115314184|UniProtKB=A0ACM8F4U4 A0ACM8F4U4 LOC115314184 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8026631|UniProtKB=A0ACM8F653 A0ACM8F653 LOC8026631 PTHR11561:SF0 PHOSPHOENOLPYRUVATE CARBOXYKINASE PHOSPHOENOLPYRUVATE CARBOXYKINASE [GTP] carbon-carbon lyase activity#GO:0016830;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;transition metal ion binding#GO:0046914;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;cation binding#GO:0043169;lyase activity#GO:0016829;metal ion binding#GO:0046872 homeostatic process#GO:0042592;carbohydrate metabolic process#GO:0005975;cellular response to stimulus#GO:0051716;hexose biosynthetic process#GO:0019319;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;response to starvation#GO:0042594;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;small molecule biosynthetic process#GO:0044283;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;response to glucose#GO:0009749;response to nutrient levels#GO:0031667;intracellular glucose homeostasis#GO:0001678;response to carbohydrate#GO:0009743;response to oxygen-containing compound#GO:1901700;oxoacid metabolic process#GO:0043436;cellular response to chemical stimulus#GO:0070887;response to monosaccharide#GO:0034284;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;carbohydrate homeostasis#GO:0033500;carboxylic acid metabolic process#GO:0019752;response to hexose#GO:0009746;glucose homeostasis#GO:0042593;glucose metabolic process#GO:0006006;chemical homeostasis#GO:0048878;monosaccharide metabolic process#GO:0005996;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cellular response to glucose stimulus#GO:0071333;carbohydrate biosynthetic process#GO:0016051;response to lipid#GO:0033993;response to chemical#GO:0042221;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;gluconeogenesis#GO:0006094;alcohol biosynthetic process#GO:0046165;response to stress#GO:0006950 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;kinase#PC00137;transferase#PC00220 Pyruvate metabolism#P02772>Phosphoenolpyruvate Carboxykinase#P03135 IXOSC|EnsemblGenome=LOC120839705|UniProtKB=A0ACM8ENJ4 A0ACM8ENJ4 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115328540|UniProtKB=A0ACM8G5A3 A0ACM8G5A3 LOC115328540 PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;exopeptidase activity#GO:0008238;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006 peptide metabolic process#GO:0006518;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508;catabolic process#GO:0009056;cellular process#GO:0009987;peptide catabolic process#GO:0043171;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC121046024|UniProtKB=A0ACM8FCP7 A0ACM8FCP7 LOC121046024 PTHR24252:SF32 ACROSIN-RELATED SERINE PROTEASE 33 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121834069|UniProtKB=A0ACM8FMR0 A0ACM8FMR0 PTHR47696:SF4 THAP DOMAIN-CONTAINING PROTEIN 2 THAP DOMAIN CONTAINING 2 IXOSC|EnsemblGenome=LOC115325031|UniProtKB=A0ACM8EHY8 A0ACM8EHY8 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8040606|UniProtKB=A0ACM8EC55 A0ACM8EC55 LOC8040606 PTHR10183:SF394 CALPAIN CALPAIN-C endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC120848845|UniProtKB=A0ACM8F7I0 A0ACM8F7I0 LOC120848845 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040384|UniProtKB=A0ACM8EES3 A0ACM8EES3 tank PTHR21389:SF0 P53 INDUCED PROTEIN ETOPOSIDE-INDUCED PROTEIN 2.4 HOMOLOG metabolic process#GO:0008152;autophagy#GO:0006914;cellular process#GO:0009987;catabolic process#GO:0009056;macroautophagy#GO:0016236;process utilizing autophagic mechanism#GO:0061919 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC115326812|UniProtKB=A0ACM8EQZ0 A0ACM8EQZ0 LOC115326812 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC121045545|UniProtKB=A0ACM8FBF2 A0ACM8FBF2 LOC121045545 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120843841|UniProtKB=A0ACM8EWZ7 A0ACM8EWZ7 LOC120843841 PTHR10907:SF47 REGUCALCIN REGUCALCIN hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;esterase#PC00097 IXOSC|EnsemblGenome=LOC8038424|UniProtKB=A0ACM8FAC8 A0ACM8FAC8 LOC8038424 PTHR45625:SF6 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-RELATED SPLICEOSOME-ASSOCIATED PROTEIN CWC27 HOMOLOG catalytic activity#GO:0003824;isomerase activity#GO:0016853;peptidyl-prolyl cis-trans isomerase activity#GO:0003755;cis-trans isomerase activity#GO:0016859;catalytic activity, acting on a protein#GO:0140096 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120841710|UniProtKB=A0ACM8ES72 A0ACM8ES72 LOC120841710 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031199|UniProtKB=A0ACM8F3F0 A0ACM8F3F0 jbug PTHR38537:SF13 JITTERBUG, ISOFORM N JITTERBUG, ISOFORM N IXOSC|EnsemblGenome=LOC120846352|UniProtKB=A0ACM8F254 A0ACM8F254 Rpb11 PTHR13946:SF16 DNA-DIRECTED RNA POLYMERASE I,II,III DNA-DIRECTED RNA POLYMERASE II SUBUNIT RPB11-A transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;transcription by RNA polymerase II#GO:0006366;nucleic acid biosynthetic process#GO:0141187;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 RNA polymerase II, holoenzyme#GO:0016591;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;DNA-directed RNA polymerase complex#GO:0000428;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;nucleoplasm#GO:0005654;RNA polymerase II, core complex#GO:0005665;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;nuclear DNA-directed RNA polymerase complex#GO:0055029;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121833171|UniProtKB=A0ACM8FJH9 A0ACM8FJH9 LOC121833171 PTHR47533:SF4 PROTEIN CBG21859 AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842547|UniProtKB=A0ACM8G5E3 A0ACM8G5E3 LOC120842547 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8039674|UniProtKB=A0ACM8E898 A0ACM8E898 LOC8039674 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8030876|UniProtKB=A0ACM8FSB6 A0ACM8FSB6 LOC8030876 PTHR10291:SF51 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;prenyltransferase activity#GO:0004659;catalytic activity#GO:0003824;transferase activity#GO:0016740 small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;isoprenoid metabolic process#GO:0006720;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610 transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8042446|UniProtKB=A0ACM8DUE6 A0ACM8DUE6 LOC8042446 PTHR11276:SF28 DNA POLYMERASE TYPE-X FAMILY MEMBER DNA POLYMERASE LAMBDA DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA-directed DNA polymerase activity#GO:0003887 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303 DNA metabolism protein#PC00009;DNA-directed DNA polymerase#PC00018 IXOSC|EnsemblGenome=LOC8028085|UniProtKB=A0ACM8FM04 A0ACM8FM04 LOC8028085 PTHR11412:SF146 MACROGLOBULIN / COMPLEMENT LD23292P endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;peptidase regulator activity#GO:0061134;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;enzyme inhibitor activity#GO:0004857;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772 immune response#GO:0006955;defense response to symbiont#GO:0140546;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;response to other organism#GO:0051707;response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;defense response to other organism#GO:0098542;response to stimulus#GO:0050896;immune system process#GO:0002376;defense response#GO:0006952;response to external stimulus#GO:0009605;innate immune response#GO:0045087 extracellular protein-containing complex#GO:0140392;catalytic complex#GO:1902494;extracellular region#GO:0005576;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115329613|UniProtKB=A0ACM8E9Z5 A0ACM8E9Z5 LOC115329613 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840243|UniProtKB=A0ACM8EMZ9 A0ACM8EMZ9 LOC120840243 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121838551|UniProtKB=A0ACM8G8N0 A0ACM8G8N0 LOC121838551 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036176|UniProtKB=A0ACM8DVE9 A0ACM8DVE9 mldr PTHR13547:SF23 RIBONUCLEASE P MITOCHONDRIAL RIBONUCLEASE P CATALYTIC SUBUNIT hydrolase activity#GO:0016787;nuclease activity#GO:0004518;catalytic activity, acting on a tRNA#GO:0140101;ribonuclease P activity#GO:0004526;RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;endoribonuclease complex#GO:1902555;ribonuclease P complex#GO:0030677;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;endonuclease complex#GO:1905348 IXOSC|EnsemblGenome=LOC121834743|UniProtKB=A0ACM8FQW4 A0ACM8FQW4 LOC121834743 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034380|UniProtKB=A0ACM8EUK3 A0ACM8EUK3 LOC8034380 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712;oxidoreductase activity#GO:0016491;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;tetrapyrrole binding#GO:0046906;binding#GO:0005488;steroid hydroxylase activity#GO:0008395 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;steroid metabolic process#GO:0008202;response to stimulus#GO:0050896;response to chemical#GO:0042221;lipid metabolic process#GO:0006629;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8024173|UniProtKB=A0ACM8EUR0 A0ACM8EUR0 LOC8024173 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter#PC00227 IXOSC|EnsemblGenome=LOC8042643|UniProtKB=A0ACM8G6L6 A0ACM8G6L6 LOC8042643 PTHR43429:SF2 PYRIDINE NUCLEOTIDE-DISULFIDE OXIDOREDUCTASE DOMAIN-CONTAINING TRNA LIGASE COMPLEX-ASSOCIATED NAD(P)H DEHYDROGENASE PYROXD1 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8035737|UniProtKB=A0ACM8ER75 A0ACM8ER75 Rab39 PTHR47979:SF53 DRAB11-RELATED FI07418P heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;guanyl nucleotide binding#GO:0019001;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity#GO:0016787;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;GTPase activity#GO:0003924 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 small GTPase#PC00208;G-protein#PC00020 IXOSC|EnsemblGenome=LOC115330569|UniProtKB=A0ACM8FL37 A0ACM8FL37 LOC115330569 PTHR22933:SF43 FI18007P1-RELATED CHITIN-BINDING TYPE-2 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8031658|UniProtKB=A0ACM8DIK4 A0ACM8DIK4 fax PTHR12289:SF78 METAXIN RELATED FAILED AXON CONNECTIONS transporter#PC00227 IXOSC|EnsemblGenome=LOC120844013|UniProtKB=A0ACM8EYJ2 A0ACM8EYJ2 LOC120844013 PTHR46481:SF16 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 BED-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833578|UniProtKB=A0ACM8FLV4 A0ACM8FLV4 LOC121833578 PTHR11475:SF147 OXIDASE/PEROXIDASE PEROXIDASIN oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;catalytic activity#GO:0003824;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 peroxidase#PC00180;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8036334|UniProtKB=A0ACM8DJY4 A0ACM8DJY4 LOC8036334 PTHR12455:SF0 NUCLEOLAR COMPLEX PROTEIN 4 NUCLEOLAR COMPLEX PROTEIN 4 HOMOLOG rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000472;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000479 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;90S preribosome#GO:0030686;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120846173|UniProtKB=A0ACM8FH92 A0ACM8FH92 LOC120846173 PTHR11616:SF321 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT ACETYLCHOLINE TRANSPORTER monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 import into cell#GO:0098657;establishment of localization#GO:0051234;amino acid transport#GO:0006865;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;nitrogen compound transport#GO:0071705;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;amino acid transmembrane transport#GO:0003333;neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816;import across plasma membrane#GO:0098739;metal ion transport#GO:0030001;carboxylic acid transmembrane transport#GO:1905039;sodium ion transport#GO:0006814 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC120836262|UniProtKB=A0ACM8FYQ7 A0ACM8FYQ7 LOC120836262 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121836686|UniProtKB=A0ACM8G0W4 A0ACM8G0W4 LOC121836686 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8026186|UniProtKB=A0ACM8DPT1 A0ACM8DPT1 LOC8026186 PTHR11662:SF462 SOLUTE CARRIER FAMILY 17 FI19708P1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8035537|UniProtKB=A0ACM8FZJ6 A0ACM8FZJ6 LOC8035537 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 lipase activity#GO:0016298;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;A2-type glycerophospholipase activity#GO:0004623 IXOSC|EnsemblGenome=LOC8034299|UniProtKB=A0ACM8DJ64 A0ACM8DJ64 LOC8034299 PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;proteolysis#GO:0006508;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;catabolic process#GO:0009056;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC120839878|UniProtKB=A0ACM8ENV6 A0ACM8ENV6 LOC120839878 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC121834186|UniProtKB=A0ACM8FN23 A0ACM8FN23 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041370|UniProtKB=A0ACM8FGM2 A0ACM8FGM2 LOC8041370 PTHR47537:SF3 CUBILIN GH12701P membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC115313789|UniProtKB=A0ACM8DTG8 A0ACM8DTG8 LOC115313789 PTHR23079:SF55 RNA-DEPENDENT RNA POLYMERASE RNA-DIRECTED RNA POLYMERASE nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on RNA#GO:0140098 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;siRNA processing#GO:0030422;negative regulation of metabolic process#GO:0009892;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8027992|UniProtKB=A0ACM8E6D5 A0ACM8E6D5 Nubp2 PTHR23264:SF19 NUCLEOTIDE-BINDING PROTEIN NBP35 YEAST -RELATED CYTOSOLIC FE-S CLUSTER ASSEMBLY FACTOR NUBP2 binding#GO:0005488;small molecule binding#GO:0036094;iron-sulfur cluster binding#GO:0051536 cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8030870|UniProtKB=A0ACM8ECR8 A0ACM8ECR8 PTHR48051:SF1 FAMILY NOT NAMED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8024017|UniProtKB=A0ACM8DHU4 A0ACM8DHU4 PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG cation binding#GO:0043169;metal ion binding#GO:0046872;calcium ion binding#GO:0005509;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC120840735|UniProtKB=A0ACM8EPS9 A0ACM8EPS9 LOC120840735 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8034883|UniProtKB=A0ACM8DXN2 A0ACM8DXN2 LOC8034883 PTHR10656:SF42 CELL FATE DETERMINING PROTEIN MAB21-RELATED CYCLIC GMP-AMP SYNTHASE-LIKE PROTEIN-RELATED transferase#PC00220;nucleotidyltransferase#PC00174 IXOSC|EnsemblGenome=LOC8044100|UniProtKB=A0ACM8ERU9 A0ACM8ERU9 LOC8044100 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC115331962|UniProtKB=A0ACM8ECX8 A0ACM8ECX8 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120841429|UniProtKB=A0ACM8ERL2 A0ACM8ERL2 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115332835|UniProtKB=A0ACM8EE60 A0ACM8EE60 LOC115332835 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8031699|UniProtKB=A0ACM8DIM7 A0ACM8DIM7 LOC8031699 PTHR11079:SF208 CYTOSINE DEAMINASE FAMILY MEMBER TRNA-SPECIFIC ADENOSINE-34 DEAMINASE CATALYTIC SUBUNIT ADAT2 catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity, acting on RNA#GO:0140098;tRNA-specific adenosine deaminase activity#GO:0008251;hydrolase activity#GO:0016787;adenosine deaminase activity#GO:0004000;catalytic activity, acting on a tRNA#GO:0140101 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;base conversion or substitution editing#GO:0016553;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;adenosine to inosine editing#GO:0006382;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 deaminase#PC00088;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dCTP deaminase#P02920;Salvage pyrimidine ribonucleotides#P02775>Cytosine deaminase#P03155;Salvage pyrimidine deoxyribonucleotides#P02774>Cytidine deaminase#P03144;Salvage pyrimidine ribonucleotides#P02775>Cytidine deaminase#P03154 IXOSC|EnsemblGenome=LOC115309781|UniProtKB=A0ACM8F5A9 A0ACM8F5A9 LOC115309781 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;developmental process#GO:0032502;post-embryonic development#GO:0009791;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;circulatory system development#GO:0072359;heart development#GO:0007507;multicellular organismal process#GO:0032501;animal organ morphogenesis#GO:0009887 cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 IXOSC|EnsemblGenome=ISCI020482|UniProtKB=B7PXE3 B7PXE3 spas PTHR23074:SF173 AAA DOMAIN-CONTAINING SPASTIN catalytic activity, acting on a protein#GO:0140096;ribonucleoside triphosphate phosphatase activity#GO:0017111;isomerase activity#GO:0016853;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;macromolecular conformation isomerase activity#GO:0120543;hydrolase activity#GO:0016787;ATP hydrolysis activity#GO:0016887;polypeptide conformation or assembly isomerase activity#GO:0120544;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 cellular developmental process#GO:0048869;neurogenesis#GO:0022008;central nervous system neuron differentiation#GO:0021953;neuron projection morphogenesis#GO:0048812;developmental process#GO:0032502;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;axon development#GO:0061564;anatomical structure development#GO:0048856;microtubule cytoskeleton organization#GO:0000226;system development#GO:0048731;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;microtubule-based process#GO:0007017;cell projection morphogenesis#GO:0048858;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron differentiation#GO:0030182;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;cytoskeleton organization#GO:0007010;neuron projection development#GO:0031175;organelle organization#GO:0006996;cellular process#GO:0009987;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell morphogenesis#GO:0000902;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell differentiation#GO:0030154;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC120850765|UniProtKB=A0ACM8FBQ2 A0ACM8FBQ2 LOC120850765 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8037604|UniProtKB=A0ACM8DI70 A0ACM8DI70 peng PTHR13389:SF0 PUMILIO HOMOLOG 3 PUMILIO HOMOLOG 3 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC115329814|UniProtKB=A0ACM8ER39 A0ACM8ER39 LOC115329814 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;metallocarboxypeptidase activity#GO:0004181;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115320851|UniProtKB=A0ACM8E182 A0ACM8E182 LOC115320851 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121834840|UniProtKB=A0ACM8FRL2 A0ACM8FRL2 LOC121834840 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120844921|UniProtKB=A0ACM8EZJ8 A0ACM8EZJ8 LOC120844921 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED cellular response to stimulus#GO:0051716;cellular process#GO:0009987;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152 intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120839480|UniProtKB=A0ACM8ELS0 A0ACM8ELS0 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC115314383|UniProtKB=A0ACM8FJ80 A0ACM8FJ80 LOC115314383 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053392|UniProtKB=A0ACM8FJ46 A0ACM8FJ46 LOC8053392 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115320944|UniProtKB=A0ACM8G5L5 A0ACM8G5L5 LOC115320944 PTHR18966:SF377 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR IONOTROPIC, NMDA 1 carboxylic acid transmembrane transporter activity#GO:0046943;ligand-gated monoatomic ion channel activity#GO:0015276;molecular transducer activity#GO:0060089;channel activity#GO:0015267;glutamate receptor activity#GO:0008066;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;dicarboxylic acid transmembrane transporter activity#GO:0005310;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;voltage-gated channel activity#GO:0022832;amino acid transmembrane transporter activity#GO:0015171;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;signaling receptor activity#GO:0038023 regulation of membrane potential#GO:0042391;cell surface receptor signaling pathway#GO:0007166;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic signaling#GO:0099536;signal transduction#GO:0007165;cellular process#GO:0009987;cell communication#GO:0007154;glutamate receptor signaling pathway#GO:0007215;regulation of biological quality#GO:0065008;trans-synaptic signaling#GO:0099537;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;signaling#GO:0023052;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;plasma membrane#GO:0005886;signaling receptor complex#GO:0043235;cell junction#GO:0030054;transporter complex#GO:1990351;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;transmembrane transporter complex#GO:1902495 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>NMDA#P01024;Metabotropic glutamate receptor group I pathway#P00041>NMDA#P01060;Huntington disease#P00029>NMDA receptor#P00778;Metabotropic glutamate receptor group III pathway#P00039>NMDA#P01039;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>NMDA#P01071;Ionotropic glutamate receptor pathway#P00037>NR1#P01010 IXOSC|EnsemblGenome=LOC115315326|UniProtKB=A0ACM8F6N8 A0ACM8F6N8 LOC115315326 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311824|UniProtKB=A0ACM8F5T9 A0ACM8F5T9 LOC115311824 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115322531|UniProtKB=A0ACM8E2S9 A0ACM8E2S9 PTHR17901:SF14 MAGNESIUM-DEPENDENT PHOSPHATASE 1 MDP1 MAGNESIUM-DEPENDENT PHOSPHATASE 1 metabolite interconversion enzyme#PC00262;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8036483|UniProtKB=A0ACM8FYH1 A0ACM8FYH1 LOC8036483 PTHR12435:SF2 FAMILY NOT NAMED PROTEIN KTI12 HOMOLOG tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 IXOSC|EnsemblGenome=LOC8051300|UniProtKB=A0ACM8EGH2 A0ACM8EGH2 LOC8051300 PTHR24082:SF507 NUCLEAR HORMONE RECEPTOR BILE ACID RECEPTOR-RELATED sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 cholesterol homeostasis#GO:0042632;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;negative regulation of response to stimulus#GO:0048585;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of inflammatory response#GO:0050727;regulation of defense response#GO:0031347;negative regulation of defense response#GO:0031348;regulation of cellular process#GO:0050794;negative regulation of inflammatory response#GO:0050728;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;homeostatic process#GO:0042592;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;chemical homeostasis#GO:0048878;regulation of response to external stimulus#GO:0032101;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of response to external stimulus#GO:0032102;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of DNA-templated transcription#GO:0045892;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;lipid homeostasis#GO:0055088;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169 IXOSC|EnsemblGenome=LOC115308596|UniProtKB=A0ACM8EKK1 A0ACM8EKK1 LOC115308596 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8024811|UniProtKB=A0ACM8FQ96 A0ACM8FQ96 LOC8024811 PTHR23189:SF102 RNA RECOGNITION MOTIF-CONTAINING PROTEIN NO-ON-TRANSIENT A binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120839697|UniProtKB=A0ACM8ELV9 A0ACM8ELV9 LOC120839697 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120844889|UniProtKB=A0ACM8F020 A0ACM8F020 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC115316709|UniProtKB=A0ACM8EP89 A0ACM8EP89 LOC115316709 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824 cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120845996|UniProtKB=A0ACM8F185 A0ACM8F185 LOC120845996 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032616|UniProtKB=A0ACM8DR74 A0ACM8DR74 ssh PTHR45864:SF2 SLINGSHOT PROTEIN PHOSPHATASE HOMOLOG PROTEIN PHOSPHATASE SLINGSHOT catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;cytoskeletal protein binding#GO:0008092;phosphatase activity#GO:0016791;hydrolase activity#GO:0016787;protein binding#GO:0005515;phosphoprotein phosphatase activity#GO:0004721;binding#GO:0005488;actin binding#GO:0003779 regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;regulation of actin filament polymerization#GO:0030833;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament organization#GO:0110053;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;regulation of protein polymerization#GO:0032271;negative regulation of supramolecular fiber organization#GO:1902904;regulation of cytoskeleton organization#GO:0051493;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex assembly#GO:0031333;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Cytoskeletal regulation by Rho GTPase#P00016>Slingshot#P00509 IXOSC|EnsemblGenome=LOC8032956|UniProtKB=A0ACM8DH93 A0ACM8DH93 LOC8032956 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 sphingolipid catabolic process#GO:0030149;primary metabolic process#GO:0044238;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;glycolipid metabolic process#GO:0006664;carbohydrate derivative catabolic process#GO:1901136;lipid localization#GO:0010876;localization#GO:0051179;ceramide metabolic process#GO:0006672;macromolecule localization#GO:0033036;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;lipid transport#GO:0006869;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;transport#GO:0006810;lipid metabolic process#GO:0006629;establishment of localization#GO:0051234 plasma membrane#GO:0005886;side of membrane#GO:0098552;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cytoplasmic side of membrane#GO:0098562;cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8051698|UniProtKB=A0ACM8DPL5 A0ACM8DPL5 LOC8051698 PTHR12147:SF26 METALLOPEPTIDASE M28 FAMILY MEMBER PEPTIDASE M28 DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120835938|UniProtKB=A0ACM8FA74 A0ACM8FA74 Mic26-27 PTHR14564:SF4 MICOS COMPLEX SUBUNIT MIC26 / MIC27 FAMILY MEMBER MICOS COMPLEX SUBUNIT cellular component organization or biogenesis#GO:0071840;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;mitochondrial membrane organization#GO:0007006;inner mitochondrial membrane organization#GO:0007007;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043 organelle envelope#GO:0031967;membrane protein complex#GO:0098796;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;inner mitochondrial membrane protein complex#GO:0098800;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC115319169|UniProtKB=A0ACM8FV30 A0ACM8FV30 LOC115319169 PTHR45655:SF13 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 GUANYLATE CYCLASE DOMAIN-CONTAINING PROTEIN cyclase#PC00079;guanylate cyclase#PC00114 IXOSC|EnsemblGenome=LOC8042393|UniProtKB=A0ACM8F283 A0ACM8F283 LOC8042393 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter#PC00227 IXOSC|EnsemblGenome=LOC8027962|UniProtKB=A0ACM8E688 A0ACM8E688 Arpc5 PTHR12644:SF5 ARP2/3 COMPLEX 16 KD SUBUNIT P16-ARC ACTIN-RELATED PROTEIN 2_3 COMPLEX SUBUNIT 5 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 Arp2/3 complex-mediated actin nucleation#GO:0034314;cellular process#GO:0009987;cellular component organization#GO:0016043;organelle organization#GO:0006996;cytoskeleton organization#GO:0007010;actin nucleation#GO:0045010;cell motility#GO:0048870;cell migration#GO:0016477;actin cytoskeleton organization#GO:0030036;actin filament-based process#GO:0030029;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;Arp2/3 protein complex#GO:0005885;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 actin or actin-binding cytoskeletal protein#PC00041 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>Arp2/3#P00876;Integrin signalling pathway#P00034>Arp2/3#P00912 IXOSC|EnsemblGenome=LOC115327890|UniProtKB=A0ACM8G4J3 A0ACM8G4J3 LOC115327890 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115319534|UniProtKB=A0ACM8FLG2 A0ACM8FLG2 LOC115319534 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8031703|UniProtKB=A0ACM8E8K1 A0ACM8E8K1 LOC8031703 PTHR24361:SF855 MITOGEN-ACTIVATED KINASE KINASE KINASE PROTEIN KINASE DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120844064|UniProtKB=A0ACM8EXF4 A0ACM8EXF4 LOC120844064 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8033121|UniProtKB=A0ACM8E934 A0ACM8E934 LOC8033121 PTHR11935:SF94 BETA LACTAMASE DOMAIN HYDROXYACYLGLUTATHIONE HYDROLASE hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;thiolester hydrolase activity#GO:0016790;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC8038336|UniProtKB=A0ACM8DVC9 A0ACM8DVC9 Cka PTHR15653:SF0 STRIATIN CONNECTOR OF KINASE TO AP-1, ISOFORM E protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of biological process#GO:0050789 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8042889|UniProtKB=A0ACM8EAB3 A0ACM8EAB3 PTHR15651:SF7 ARMADILLO REPEAT-CONTAINING PROTEIN 8 ARMADILLO REPEAT-CONTAINING PROTEIN 8 macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 IXOSC|EnsemblGenome=LOC115309564|UniProtKB=A0ACM8FDU0 A0ACM8FDU0 Urm1 PTHR14986:SF4 RURM1 PROTEIN UBIQUITIN-RELATED MODIFIER 1 post-translational protein modification#GO:0043687;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8031939|UniProtKB=A0ACM8E8V2 A0ACM8E8V2 PTHR23129:SF0 ACYL-COENZYME A DIPHOSPHATASE FITM2 ACYL-COENZYME A DIPHOSPHATASE FITM2 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 homeostatic process#GO:0042592;cellular component assembly#GO:0022607;cellular process#GO:0009987;lipid storage#GO:0019915;cellular component organization#GO:0016043;lipid homeostasis#GO:0055088;membraneless organelle assembly#GO:0140694;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization or biogenesis#GO:0071840;chemical homeostasis#GO:0048878;lipid droplet organization#GO:0034389;organelle assembly#GO:0070925 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 phosphatase#PC00181;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120839683|UniProtKB=A0ACM8EMW4 A0ACM8EMW4 LOC120839683 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029135|UniProtKB=A0ACM8DHN5 A0ACM8DHN5 LOC8029135 PTHR10494:SF6 BONE MORPHOGENETIC PROTEIN INHIBITOR, NOGGIN NOGGIN negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of biological process#GO:0050789;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;regulation of BMP signaling pathway#GO:0030510 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8031349|UniProtKB=A0ACM8G4G8 A0ACM8G4G8 LOC8031349 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8051891|UniProtKB=A0ACM8E791 A0ACM8E791 LOC8051891 PTHR12869:SF0 SMALL SEVEN TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN BOS COMPLEX SUBUNIT TMEM147 IXOSC|EnsemblGenome=LOC8039942|UniProtKB=A0ACM8DYJ5 A0ACM8DYJ5 Start1 PTHR46121:SF4 STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE STEROIDOGENIC ACUTE REGULATORY PROTEIN-LIKE membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;organelle membrane contact site#GO:0044232;vesicle#GO:0031982;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;late endosome membrane#GO:0031902;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;late endosome#GO:0005770;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8026406|UniProtKB=A0ACM8DHQ0 A0ACM8DHQ0 RpL31 PTHR10956:SF0 60S RIBOSOMAL PROTEIN L31 LARGE RIBOSOMAL SUBUNIT PROTEIN EL31 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;ribosome#GO:0005840;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8053068|UniProtKB=A0ACM8F6R0 A0ACM8F6R0 LOC8053068 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;transferase activity#GO:0016740;catalytic activity#GO:0003824 glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058 IXOSC|EnsemblGenome=LOC8028349|UniProtKB=A0ACM8DU27 A0ACM8DU27 LOC8028349 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;monocarboxylic acid biosynthetic process#GO:0072330 intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8031331|UniProtKB=A0ACM8FYB7 A0ACM8FYB7 LOC8031331 PTHR45629:SF16 SNF2/RAD54 FAMILY MEMBER DNA REPAIR AND RECOMBINATION PROTEIN RAD54B DNA translocase activity#GO:0015616;ATP-dependent activity#GO:0140657;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity, acting on DNA#GO:0008094 cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;response to stimulus#GO:0050896;double-strand break repair via homologous recombination#GO:0000724;cell cycle process#GO:0022402;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;homologous recombination#GO:0035825;reproductive process#GO:0022414;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;organelle fission#GO:0048285;sexual reproduction#GO:0019953;recombinational repair#GO:0000725;meiosis I cell cycle process#GO:0061982 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 damaged DNA-binding protein#PC00086 IXOSC|EnsemblGenome=LOC8029622|UniProtKB=A0ACM8DIH1 A0ACM8DIH1 LOC8029622 PTHR42650:SF1 TAIL-ANCHORED PROTEIN INSERTION RECEPTOR WRB GUIDED ENTRY OF TAIL-ANCHORED PROTEINS FACTOR 1 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-membrane adaptor activity#GO:0043495 protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;protein insertion into ER membrane#GO:0045048;endoplasmic reticulum organization#GO:0007029;cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104 endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC8037842|UniProtKB=A0ACM8EG34 A0ACM8EG34 LOC8037842 PTHR43842:SF2 PROPIONYL-COA CARBOXYLASE BETA CHAIN PROPIONYL-COA CARBOXYLASE BETA CHAIN, MITOCHONDRIAL ligase activity#GO:0016874;catalytic activity#GO:0003824 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 ligase#PC00142;metabolite interconversion enzyme#PC00262 Succinate to proprionate conversion#P02777>Methylmalonyl-CoA decarboxylase#P03163;Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 IXOSC|EnsemblGenome=LOC8031733|UniProtKB=A0ACM8DIL4 A0ACM8DIL4 LOC8031733 PTHR45842:SF12 SYNAPTIC ADHESION-LIKE MOLECULE SALM TIR DOMAIN-CONTAINING PROTEIN cell adhesion molecule#PC00069;immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121835628|UniProtKB=A0ACM8FVY4 A0ACM8FVY4 LOC121835628 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027457|UniProtKB=A0ACM8EMK5 A0ACM8EMK5 LOC8027457 PTHR20963:SF56 MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum lumen#GO:0005788;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;extracellular region#GO:0005576;endoplasmic reticulum#GO:0005783 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121048492|UniProtKB=A0ACM8FJG2 A0ACM8FJG2 LOC121048492 PTHR11177:SF410 CHITINASE HISTIDINE-RICH CARBOXYL TERMINUS PROTEIN 1 ISOFORM X1 hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568 carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;chitin metabolic process#GO:0006030;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8053442|UniProtKB=A0ACM8F914 A0ACM8F914 LOC8053442 PTHR43347:SF5 ACYL-COA SYNTHETASE ACYL-COA SYNTHETASE SHORT-CHAIN FAMILY MEMBER 3, MITOCHONDRIAL ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226 metabolite interconversion enzyme#PC00262;ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 IXOSC|EnsemblGenome=LOC115323697|UniProtKB=A0ACM8E4F2 A0ACM8E4F2 LOC115323697 PTHR23080:SF63 THAP DOMAIN PROTEIN DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053731|UniProtKB=A0ACM8FHQ3 A0ACM8FHQ3 PTHR12549:SF11 JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN LYSINE-SPECIFIC DEMETHYLASE 3 histone modifying activity#GO:0140993;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;protein demethylase activity#GO:0140457;histone demethylase activity#GO:0032452;chromatin DNA binding#GO:0031490;catalytic activity#GO:0003824;transcription coregulator activity#GO:0003712 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8043637|UniProtKB=A0ACM8DQT2 A0ACM8DQT2 PTHR22426:SF2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 ARGININE_SERINE-RICH COILED-COIL PROTEIN 2 IXOSC|EnsemblGenome=LOC120845829|UniProtKB=A0ACM8F085 A0ACM8F085 LOC120845829 PTHR18966:SF602 IONOTROPIC GLUTAMATE RECEPTOR GLUTAMATE RECEPTOR 1-RELATED signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;transmembrane transporter activity#GO:0022857;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;channel activity#GO:0015267;molecular transducer activity#GO:0060089;ligand-gated monoatomic ion channel activity#GO:0015276 modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;regulation of cell communication#GO:0010646;anterograde trans-synaptic signaling#GO:0098916;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;cell communication#GO:0007154;regulation of signaling#GO:0023051;trans-synaptic signaling#GO:0099537;cell-cell signaling#GO:0007267;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;regulation of trans-synaptic signaling#GO:0099177;cellular process#GO:0009987;synaptic signaling#GO:0099536 cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynapse#GO:0098794;postsynaptic density membrane#GO:0098839;postsynaptic density#GO:0014069;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;plasma membrane#GO:0005886;neuron to neuron synapse#GO:0098984;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;cell periphery#GO:0071944;membrane#GO:0016020;cell junction#GO:0030054;synaptic membrane#GO:0097060 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>Glu1#P01018;Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Metabotropic glutamate receptor group III pathway#P00039>A/K#P01046;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC120842515|UniProtKB=A0ACM8EU06 A0ACM8EU06 LOC120842515 PTHR45913:SF5 EPM2A-INTERACTING PROTEIN 1 HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031207|UniProtKB=A0ACM8FBL2 A0ACM8FBL2 LOC8031207 PTHR46652:SF3 LEUCINE-RICH REPEAT AND IQ DOMAIN-CONTAINING PROTEIN 1-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 9 IXOSC|EnsemblGenome=LOC8036807|UniProtKB=A0ACM8E1U6 A0ACM8E1U6 LOC8036807 PTHR11480:SF102 SAPOSIN-RELATED BCDNA.GH08312 chemical homeostasis#GO:0048878;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;cellular process#GO:0009987;lipid homeostasis#GO:0055088;primary metabolic process#GO:0044238;homeostatic process#GO:0042592 lytic vacuole#GO:0000323;late endosome#GO:0005770;endomembrane system#GO:0012505;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;lysosome#GO:0005764;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027419|UniProtKB=A0ACM8EJR5 A0ACM8EJR5 LOC8027419 PTHR10751:SF29 GUANYLATE BINDING PROTEIN ATLASTIN GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029 G-protein#PC00020;heterotrimeric G-protein#PC00117 IXOSC|EnsemblGenome=LOC115328055|UniProtKB=A0ACM8E7K7 A0ACM8E7K7 LOC115328055 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120847387|UniProtKB=A0ACM8FT31 A0ACM8FT31 LOC120847387 PTHR16821:SF2 FRATAXIN FRATAXIN, MITOCHONDRIAL cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;iron-sulfur cluster assembly#GO:0016226 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120846665|UniProtKB=A0ACM8F2Y9 A0ACM8F2Y9 LOC120846665 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8040067|UniProtKB=A0ACM8E3Z5 A0ACM8E3Z5 LOC8040067 PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;lysosome#GO:0005764;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 glycosidase#PC00110;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120835976|UniProtKB=A0ACM8EMI6 A0ACM8EMI6 LOC120835976 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC8035306|UniProtKB=A0ACM8DWQ4 A0ACM8DWQ4 LOC8035306 PTHR31340:SF3 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 MITOCHONDRIAL GENOME MAINTENANCE EXONUCLEASE 1 exonuclease activity#GO:0004527;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;DNA exonuclease activity#GO:0004529;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097 IXOSC|EnsemblGenome=LOC120850736|UniProtKB=A0ACM8FAN0 A0ACM8FAN0 LOC120850736 PTHR47696:SF4 THAP DOMAIN-CONTAINING PROTEIN 2 THAP DOMAIN CONTAINING 2 IXOSC|EnsemblGenome=LOC8037704|UniProtKB=A0ACM8G266 A0ACM8G266 LOC8037704 PTHR24258:SF147 SERINE PROTEASE-RELATED FI16631P1-RELATED serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8036975|UniProtKB=A0ACM8E0J7 A0ACM8E0J7 PTHR44163:SF1 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 4 HOMOLOG nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;rRNA metabolic process#GO:0016072;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;macromolecule biosynthetic process#GO:0009059;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of DNA-templated transcription#GO:0006355;rRNA processing#GO:0006364;regulation of RNA metabolic process#GO:0051252;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;RNA biosynthetic process#GO:0032774 preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;t-UTP complex#GO:0034455;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8032951|UniProtKB=A0ACM8DVM4 A0ACM8DVM4 SERCA PTHR42861:SF102 CALCIUM-TRANSPORTING ATPASE CALCIUM-TRANSPORTING ATPASE SARCOPLASMIC_ENDOPLASMIC RETICULUM TYPE P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATPase-coupled transmembrane transporter activity#GO:0042626 establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;metal ion transport#GO:0030001;homeostatic process#GO:0042592;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873 membrane#GO:0016020;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120849122|UniProtKB=A0ACM8F726 A0ACM8F726 PTHR10334:SF517 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8033986|UniProtKB=A0ACM8DIP9 A0ACM8DIP9 LOC8033986 PTHR46239:SF1 DNA REPAIR PROTEIN RAD51 HOMOLOG 3 RAD51C DNA REPAIR PROTEIN RAD51 HOMOLOG 3 four-way junction DNA binding#GO:0000400;nuclease activity#GO:0004518;DNA binding#GO:0003677;DNA endonuclease activity#GO:0004520;hydrolase activity#GO:0016787;nucleic acid binding#GO:0003676;binding#GO:0005488;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 cellular component assembly#GO:0022607;protein-DNA complex assembly#GO:0065004;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;protein-DNA complex organization#GO:0071824;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;double-strand break repair#GO:0006302;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;response to stimulus#GO:0050896;meiotic cell cycle process#GO:1903046;meiosis I#GO:0007127;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;nucleobase-containing compound metabolic process#GO:0006139;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;DNA repair#GO:0006281;DNA damage response#GO:0006974;reproductive process#GO:0022414;homologous recombination#GO:0035825;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;organelle fission#GO:0048285;meiosis I cell cycle process#GO:0061982;recombinational repair#GO:0000725;sexual reproduction#GO:0019953 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634;replication fork#GO:0005657 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115313733|UniProtKB=A0ACM8F034 A0ACM8F034 LOC115313733 PTHR11733:SF224 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED NEPRILYSIN-2 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8024966|UniProtKB=A0ACM8DRD8 A0ACM8DRD8 LOC8024966 PTHR11802:SF3 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120850894|UniProtKB=A0ACM8FB60 A0ACM8FB60 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115326472|UniProtKB=A0ACM8E7F0 A0ACM8E7F0 LOC115326472 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115314634|UniProtKB=A0ACM8FGH1 A0ACM8FGH1 LOC115314634 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8031799|UniProtKB=A0ACM8EEV0 A0ACM8EEV0 LOC8031799 PTHR18976:SF34 APOLIPOPROTEIN LIPID-BINDING PROTEIN transfer/carrier protein#PC00219;apolipoprotein#PC00052 IXOSC|EnsemblGenome=LOC120842247|UniProtKB=A0ACM8ET46 A0ACM8ET46 Opa1 PTHR11566:SF67 DYNAMIN DYNAMIN-LIKE GTPASE OPA1, MITOCHONDRIAL binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;microtubule binding#GO:0008017;protein binding#GO:0005515;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;tubulin binding#GO:0015631;hydrolase activity, acting on acid anhydrides#GO:0016817;cytoskeletal protein binding#GO:0008092;ribonucleoside triphosphate phosphatase activity#GO:0017111 cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrial fusion#GO:0008053;cellular component organization#GO:0016043;mitochondrion organization#GO:0007005;cellular component organization or biogenesis#GO:0071840;organelle fusion#GO:0048284 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;microtubule cytoskeleton#GO:0015630;membrane#GO:0016020;membrane-enclosed lumen#GO:0031974;organelle membrane#GO:0031090;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;mitochondrial intermembrane space#GO:0005758;cytoskeleton#GO:0005856;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;organelle envelope#GO:0031967;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;microtubule#GO:0005874;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8053265|UniProtKB=A0ACM8DMU6 A0ACM8DMU6 LOC8053265 PTHR23291:SF131 BAX INHIBITOR-RELATED TRANSMEMBRANE BAX INHIBITOR MOTIF CONTAINING 7 calcium ion transmembrane transporter activity#GO:0015085;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857 biological regulation#GO:0065007;endoplasmic reticulum unfolded protein response#GO:0030968;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell communication#GO:0007154;response to unfolded protein#GO:0006986;intracellular signal transduction#GO:0035556;response to endoplasmic reticulum stress#GO:0034976;cellular response to unfolded protein#GO:0034620;cellular response to topologically incorrect protein#GO:0035967;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8031629|UniProtKB=A0ACM8E1I8 A0ACM8E1I8 LOC8031629 PTHR45760:SF2 FI19922P1-RELATED FI19922P1-RELATED mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115321007|UniProtKB=A0ACM8FVN4 A0ACM8FVN4 LOC115321007 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115323679|UniProtKB=A0ACM8E359 A0ACM8E359 Fkbp14 PTHR46222:SF3 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP7/14 PEPTIDYLPROLYL ISOMERASE chaperone#PC00072 IXOSC|EnsemblGenome=LOC121046212|UniProtKB=A0ACM8G3N8 A0ACM8G3N8 LOC121046212 PTHR19303:SF82 TRANSPOSON HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120843819|UniProtKB=A0ACM8EY01 A0ACM8EY01 LOC120843819 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028357|UniProtKB=A0ACM8DSI2 A0ACM8DSI2 LOC8028357 PTHR19957:SF83 SYNTAXIN SYNTAXIN-16 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 vesicle fusion#GO:0006906;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;organelle organization#GO:0006996;membrane fusion#GO:0061025;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 intracellular anatomical structure#GO:0005622;membrane#GO:0016020;membrane protein complex#GO:0098796;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;SNARE complex#GO:0031201;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737 SNARE protein#PC00034 Nicotinic acetylcholine receptor signaling pathway#P00044>SNARE Complex#P01091;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>SNARE Complex#P01079 IXOSC|EnsemblGenome=LOC115320185|UniProtKB=A0ACM8DZY9 A0ACM8DZY9 LOC115320185 PTHR13184:SF5 37S RIBOSOMAL PROTEIN S22 METHYLTRANSFERASE-LIKE PROTEIN 17, MITOCHONDRIAL structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8034329|UniProtKB=A0ACM8E9B7 A0ACM8E9B7 LOC8034329 PTHR48025:SF33 OS02G0815200 PROTEIN RNA-BINDING PROTEIN 34 IXOSC|EnsemblGenome=LOC8026217|UniProtKB=A0ACM8E1B3 A0ACM8E1B3 mTerf5 PTHR15437:SF7 TRANSCRIPTION TERMINATION FACTOR, MITOCHONDRIAL TRANSCRIPTION TERMINATION FACTOR 5, MITOCHONDRIAL DNA binding#GO:0003677;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;binding#GO:0005488 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;mitochondrial RNA metabolic process#GO:0000959;RNA metabolic process#GO:0016070;mitochondrial gene expression#GO:0140053;DNA-templated transcription termination#GO:0006353;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;mitochondrial transcription#GO:0006390;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170 intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8023350|UniProtKB=A0ACM8FC71 A0ACM8FC71 RpL6 PTHR10715:SF0 60S RIBOSOMAL PROTEIN L6 LARGE RIBOSOMAL SUBUNIT PROTEIN EL6 structural molecule activity#GO:0005198;RNA binding#GO:0003723;structural constituent of ribosome#GO:0003735;binding#GO:0005488;nucleic acid binding#GO:0003676 protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412 intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115311049|UniProtKB=A0ACM8DQK2 A0ACM8DQK2 LOC115311049 PTHR23235:SF130 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 367 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121834261|UniProtKB=A0ACM8FPM6 A0ACM8FPM6 PTHR45957:SF1 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 ANAPHASE-PROMOTING COMPLEX SUBUNIT 2 protein modification by small protein conjugation or removal#GO:0070647;mitotic cell cycle phase transition#GO:0044772;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;cell cycle#GO:0007049;protein K11-linked ubiquitination#GO:0070979;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;protein polyubiquitination#GO:0000209;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cellular component organization#GO:0051128;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of chromosome organization#GO:0033044;metabolic process#GO:0008152;metaphase/anaphase transition of cell cycle#GO:0044784;regulation of chromosome segregation#GO:0051983;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;cellular process#GO:0009987;post-translational protein modification#GO:0043687;regulation of cell cycle process#GO:0010564;protein ubiquitination#GO:0016567;biological regulation#GO:0065007 intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ubiquitin ligase complex#GO:0000151;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152 Cell cycle#P00013>APC#P00481 IXOSC|EnsemblGenome=LOC120845812|UniProtKB=A0ACM8F0T0 A0ACM8F0T0 LOC120845812 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8030013|UniProtKB=A0ACM8E5N6 A0ACM8E5N6 PTHR12083:SF9 BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphatase activity#GO:0016791;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphotransferase activity, alcohol group as acceptor#GO:0016773;nucleobase-containing compound kinase activity#GO:0019205 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;phosphatase#PC00181;nucleotide phosphatase#PC00173 IXOSC|EnsemblGenome=LOC8024773|UniProtKB=A0ACM8EAV0 A0ACM8EAV0 LOC8024773 PTHR12619:SF21 RFX TRANSCRIPTION FACTOR FAMILY RFX-TYPE WINGED-HELIX DOMAIN-CONTAINING PROTEIN transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8043709|UniProtKB=A0ACM8DGV2 A0ACM8DGV2 LOC8043709 PTHR10681:SF182 THIOREDOXIN PEROXIDASE THIOREDOXIN-DEPENDENT PEROXIDE REDUCTASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on peroxide as acceptor#GO:0016684;peroxidase activity#GO:0004601;antioxidant activity#GO:0016209;catalytic activity#GO:0003824 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cell redox homeostasis#GO:0045454;cellular homeostasis#GO:0019725;response to oxidative stress#GO:0006979;cellular process#GO:0009987;response to stress#GO:0006950;homeostatic process#GO:0042592;hydrogen peroxide metabolic process#GO:0042743;catabolic process#GO:0009056;response to stimulus#GO:0050896 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 peroxidase#PC00180;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053063|UniProtKB=A0ACM8E1V6 A0ACM8E1V6 RpS24 PTHR10496:SF0 40S RIBOSOMAL PROTEIN S24 40S RIBOSOMAL PROTEIN S24 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115317821|UniProtKB=A0ACM8FLU5 A0ACM8FLU5 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8029708|UniProtKB=A0ACM8E8B8 A0ACM8E8B8 LOC8029708 PTHR15688:SF1 KINETOCHORE-ASSOCIATED PROTEIN 1 KINETOCHORE-ASSOCIATED PROTEIN 1 small GTPase binding#GO:0031267;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 signal transduction#GO:0007165;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of sister chromatid segregation#GO:0033046;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;negative regulation of chromosome segregation#GO:0051985;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;protein-containing complex assembly#GO:0065003;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;nuclear chromosome segregation#GO:0098813;negative regulation of cell cycle phase transition#GO:1901988;sister chromatid segregation#GO:0000819;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;nuclear division#GO:0000280;protein localization to kinetochore#GO:0034501;biological regulation#GO:0065007;regulation of mitotic metaphase/anaphase transition#GO:0030071;negative regulation of cellular process#GO:0048523;negative regulation of chromosome separation#GO:1905819;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;negative regulation of organelle organization#GO:0010639;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of mitotic sister chromatid segregation#GO:0033047;kinetochore organization#GO:0051383;mitotic spindle assembly checkpoint signaling#GO:0007094;regulation of cell cycle process#GO:0010564;cellular component assembly#GO:0022607;cell cycle checkpoint signaling#GO:0000075;chromosome segregation#GO:0007059;regulation of chromosome segregation#GO:0051983;negative regulation of cell cycle#GO:0045786;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;negative regulation of mitotic sister chromatid separation#GO:2000816;kinetochore assembly#GO:0051382;negative regulation of mitotic cell cycle#GO:0045930;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic cell cycle#GO:0007346;mitotic sister chromatid segregation#GO:0000070;macromolecule localization#GO:0033036;regulation of nuclear division#GO:0051783;negative regulation of nuclear division#GO:0051784;negative regulation of cell cycle process#GO:0010948;regulation of chromosome organization#GO:0033044;regulation of mitotic nuclear division#GO:0007088;intracellular protein localization#GO:0008104;regulation of mitotic sister chromatid separation#GO:0010965;mitotic cell cycle checkpoint signaling#GO:0007093;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle#GO:0000278;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;negative regulation of chromosome organization#GO:2001251;organelle assembly#GO:0070925;intracellular signal transduction#GO:0035556;localization#GO:0051179;cell communication#GO:0007154;organelle fission#GO:0048285 microtubule cytoskeleton#GO:0015630;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;spindle#GO:0005819;chromosome, centromeric region#GO:0000775;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;kinetochore#GO:0000776;chromosome#GO:0005694;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;microtubule#GO:0005874;spindle microtubule#GO:0005876 IXOSC|EnsemblGenome=LOC8037998|UniProtKB=A0ACM8DPU6 A0ACM8DPU6 PTHR11662:SF279 SOLUTE CARRIER FAMILY 17 VOLTAGE-GATED PURINE NUCLEOTIDE UNIPORTER SLC17A9 transport#GO:0006810;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;nucleobase-containing compound transport#GO:0015931;localization#GO:0051179;organophosphate ester transport#GO:0015748 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8036062|UniProtKB=A0ACM8DJX4 A0ACM8DJX4 LOC8036062 PTHR11559:SF370 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE-RELATED esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 IXOSC|EnsemblGenome=LOC121047091|UniProtKB=A0ACM8G093 A0ACM8G093 LOC121047091 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326523|UniProtKB=A0ACM8E632 A0ACM8E632 LOC115326523 PTHR24068:SF467 UBIQUITIN-CONJUGATING ENZYME E2 UBC CORE DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein polyubiquitination#GO:0000209;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;primary metabolic process#GO:0044238;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC120842785|UniProtKB=A0ACM8EVP2 A0ACM8EVP2 LOC120842785 PTHR14882:SF1 COILED-COIL DOMAIN-CONTAINING 74A CCDC92_74 N-TERMINAL DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046860|UniProtKB=A0ACM8FEX2 A0ACM8FEX2 LOC121046860 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313365|UniProtKB=A0ACM8DSR4 A0ACM8DSR4 LOC121837698 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121837470|UniProtKB=A0ACM8G4Y2 A0ACM8G4Y2 LOC121837470 PTHR23248:SF9 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 lipid localization#GO:0010876;localization#GO:0051179;plasma membrane organization#GO:0007009;regulation of biological quality#GO:0065008;cellular component organization#GO:0016043;organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid transport#GO:0006869;endomembrane system organization#GO:0010256;phospholipid translocation#GO:0045332;phospholipid transport#GO:0015914;membrane organization#GO:0061024;biological regulation#GO:0065007 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120842251|UniProtKB=A0ACM8ETF6 A0ACM8ETF6 LOC120842251 PTHR22654:SF2 G PROTEIN PATHWAY SUPPRESSOR 2 G PROTEIN PATHWAY SUPPRESSOR 2 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8024028|UniProtKB=A0ACM8G5L0 A0ACM8G5L0 LOC8024028 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8033263|UniProtKB=A0ACM8G0E0 A0ACM8G0E0 LOC8033263 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC120850601|UniProtKB=A0ACM8FAK7 A0ACM8FAK7 LOC120850601 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121835051|UniProtKB=A0ACM8FS80 A0ACM8FS80 LOC121835051 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC120844441|UniProtKB=A0ACM8FUZ5 A0ACM8FUZ5 LOC120844441 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8029789|UniProtKB=A0ACM8G858 A0ACM8G858 Pburs PTHR41151:SF1 PARTNER OF BURSICON PARTNER OF BURSICON receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;neuropeptide hormone activity#GO:0005184;hormone activity#GO:0005179;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8030695|UniProtKB=A0ACM8DUA8 A0ACM8DUA8 Zip102B PTHR16133:SF0 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER , MEMBER 9-RELATED ZINC_IRON REGULATED TRANSPORTER-RELATED PROTEIN 102B, ISOFORM E secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120843047|UniProtKB=A0ACM8EV62 A0ACM8EV62 LOC120843047 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8038990|UniProtKB=A0ACM8DT97 A0ACM8DT97 LOC8038990 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 metabolite interconversion enzyme#PC00262;methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC8042252|UniProtKB=A0ACM8FKM9 A0ACM8FKM9 LOC8042252 PTHR12546:SF60 FER-1-LIKE MISFIRE, ISOFORM F plasma membrane organization#GO:0007009;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;cellular component organization#GO:0016043;cellular process#GO:0009987 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8052250|UniProtKB=A0ACM8FS22 A0ACM8FS22 LOC8052250 PTHR21229:SF86 LUNG SEVEN TRANSMEMBRANE RECEPTOR GH17801P localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8023406|UniProtKB=A0ACM8E9T5 A0ACM8E9T5 LOC8023406 PTHR22950:SF703 AMINO ACID TRANSPORTER AMINO ACID TRANSPORTER AVT1J-LIKE amino acid transmembrane transporter activity#GO:0015171;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;L-amino acid transmembrane transporter activity#GO:0015179 cellular process#GO:0009987;amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 amino acid transporter#PC00046;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8050648|UniProtKB=A0ACM8FTB4 A0ACM8FTB4 LOC8050648 PTHR42884:SF38 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED FURIN-LIKE PROTEASE 1, ISOFORMS 1_1-X_2 catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;proteolysis#GO:0006508;regulation of biological quality#GO:0065008;protein metabolic process#GO:0019538;signaling receptor ligand precursor processing#GO:0140448;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;peptide hormone processing#GO:0016486;biological regulation#GO:0065007;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;hormone metabolic process#GO:0042445;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 serine protease#PC00203 Alzheimer disease-amyloid secretase pathway#P00003>Furin#P00105;DPP signaling pathway#P06213>FUR1#P06290;BMP/activin signaling pathway-drosophila#P06211>Furin#P06244;Activin beta signaling pathway#P06210>FUR1#P06238;DPP-SCW signaling pathway#P06212>FUR1#P06263;GBB signaling pathway#P06214>FUR1#P06298;SCW signaling pathway#P06216>FUR1#P06333;Endothelin signaling pathway#P00019>furin#P00575;MYO signaling pathway#P06215>FUR1#P06318;ALP23B signaling pathway#P06209>FUR1#P06227;Alzheimer disease-presenilin pathway#P00004>Furin#P00157 IXOSC|EnsemblGenome=LOC8032285|UniProtKB=A0ACM8EPJ3 A0ACM8EPJ3 LOC8032285 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 cellular process#GO:0009987;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;small molecule catabolic process#GO:0044282;carbohydrate metabolic process#GO:0005975;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;monosaccharide metabolic process#GO:0005996;metabolic process#GO:0008152;carbohydrate catabolic process#GO:0016052 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120839088|UniProtKB=A0ACM8EKP5 A0ACM8EKP5 PTHR23055:SF201 CALCIUM BINDING PROTEINS NEUROCALCIN HOMOLOG metal ion binding#GO:0046872;cation binding#GO:0043169;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8028620|UniProtKB=A0ACM8E3U4 A0ACM8E3U4 LOC8028620 PTHR11958:SF99 SODIUM/DICARBOXYLATE SYMPORTER-RELATED EXCITATORY AMINO ACID TRANSPORTER solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;carboxylic acid transmembrane transporter activity#GO:0046943;solute:monoatomic cation symporter activity#GO:0015294;dicarboxylic acid transmembrane transporter activity#GO:0005310;L-glutamate transmembrane transporter activity#GO:0005313;active transmembrane transporter activity#GO:0022804;acidic amino acid transmembrane transporter activity#GO:0015172;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;neutral L-amino acid transmembrane transporter activity#GO:0015175;transmembrane transporter activity#GO:0022857;sodium:dicarboxylate symporter activity#GO:0017153;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;monoatomic ion transmembrane transporter activity#GO:0015075;metal ion transmembrane transporter activity#GO:0046873;amino acid transmembrane transporter activity#GO:0015171;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215 L-alpha-amino acid transmembrane transport#GO:1902475;carboxylic acid transmembrane transport#GO:1905039;L-glutamate import#GO:0051938;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;L-glutamate transmembrane transport#GO:0015813;carboxylic acid transport#GO:0046942;acidic amino acid transport#GO:0015800;transport#GO:0006810;organic acid transport#GO:0015849;amino acid transport#GO:0006865;establishment of localization#GO:0051234 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068 Metabotropic glutamate receptor group III pathway#P00039>EAAT#P01036;Ionotropic glutamate receptor pathway#P00037>EAAT#P01011 IXOSC|EnsemblGenome=LOC120837910|UniProtKB=A0ACM8FJN5 A0ACM8FJN5 LOC120837910 PTHR33776:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033963|UniProtKB=A0ACM8E4W9 A0ACM8E4W9 LOC8033963 PTHR11348:SF17 CONNECTIVE TISSUE GROWTH FACTOR-RELATED CCN integrin binding#GO:0005178;carbohydrate derivative binding#GO:0097367;heparin binding#GO:0008201;cell adhesion molecule binding#GO:0050839;protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;signaling receptor binding#GO:0005102;glycosaminoglycan binding#GO:0005539 regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597;positive regulation of developmental process#GO:0051094;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cell communication#GO:0007154;cell adhesion#GO:0007155;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of developmental process#GO:0050793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 growth factor#PC00112;intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8052985|UniProtKB=A0ACM8FSJ3 A0ACM8FSJ3 LOC8052985 PTHR19134:SF562 RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE FI18312P1 catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein tyrosine phosphatase activity#GO:0004725;phosphoprotein phosphatase activity#GO:0004721 cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 protein phosphatase#PC00195;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8037445|UniProtKB=A0ACM8E2D9 A0ACM8E2D9 LOC8037445 PTHR12411:SF917 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN L, LIKE-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 extracellular region#GO:0005576;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 protein modifying enzyme#PC00260;cysteine protease#PC00081;protease#PC00190 IXOSC|EnsemblGenome=LOC115315489|UniProtKB=A0ACM8EMY6 A0ACM8EMY6 LOC115315489 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115315896|UniProtKB=A0ACM8EW20 A0ACM8EW20 LOC115315896 PTHR18945:SF940 NEUROTRANSMITTER GATED ION CHANNEL NICOTINIC ACETYLCHOLINE RECEPTOR ALPHA7, ISOFORM E transporter activity#GO:0005215;neurotransmitter receptor activity#GO:0030594;signaling receptor activity#GO:0038023;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;postsynaptic neurotransmitter receptor activity#GO:0098960;gated channel activity#GO:0022836;monoatomic cation transmembrane transporter activity#GO:0008324;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;monoatomic cation channel activity#GO:0005261;transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;molecular transducer activity#GO:0060089 transport#GO:0006810;calcium ion transport#GO:0006816;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;cellular process#GO:0009987;synaptic signaling#GO:0099536;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;synaptic transmission, cholinergic#GO:0007271;trans-synaptic signaling#GO:0099537;monoatomic ion transport#GO:0006811;regulation of biological quality#GO:0065008;transmembrane transport#GO:0055085;localization#GO:0051179;cell communication#GO:0007154;monoatomic cation transport#GO:0006812;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;metal ion transport#GO:0030001;anterograde trans-synaptic signaling#GO:0098916 plasma membrane#GO:0005886;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;signaling receptor complex#GO:0043235 ligand-gated ion channel#PC00141 Alzheimer disease-amyloid secretase pathway#P00003>alpha7 nicotinic acetylcholine receptor#P00079;Nicotinic acetylcholine receptor signaling pathway#P00044>alpha#P01088;Nicotinic acetylcholine receptor signaling pathway#P00044>nAChR#P01086 IXOSC|EnsemblGenome=LOC121837213|UniProtKB=A0ACM8G2T5 A0ACM8G2T5 LOC121837213 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115310003|UniProtKB=A0ACM8DPE5 A0ACM8DPE5 LOC115310003 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC115322258|UniProtKB=A0ACM8E2K3 A0ACM8E2K3 LOC115322258 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115321880|UniProtKB=A0ACM8E1H8 A0ACM8E1H8 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023212|UniProtKB=A0ACM8FA82 A0ACM8FA82 LOC8023212 PTHR11388:SF161 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;basal plasma membrane#GO:0009925;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323 transporter#PC00227 IXOSC|EnsemblGenome=LOC120841514|UniProtKB=A0ACM8ERT4 A0ACM8ERT4 LOC120841514 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037656|UniProtKB=A0ACM8DM67 A0ACM8DM67 LOC8037656 PTHR12838:SF0 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11 U3 SMALL NUCLEOLAR RNA-ASSOCIATED PROTEIN 11-RELATED intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;small-subunit processome#GO:0032040;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8028885|UniProtKB=A0ACM8ERU6 A0ACM8ERU6 LOC8028885 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC120840294|UniProtKB=A0ACM8ENK0 A0ACM8ENK0 LOC120840294 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8036695|UniProtKB=A0ACM8FN24 A0ACM8FN24 kn PTHR10747:SF38 TRANSCRIPTION FACTOR COE FAMILY MEMBER TRANSCRIPTION FACTOR COLLIER RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;P53-like transcription factor#PC00253 IXOSC|EnsemblGenome=LOC8053151|UniProtKB=A0ACM8DM30 A0ACM8DM30 LOC8053151 PTHR13691:SF73 RIBOSOMAL PROTEIN L2 LARGE RIBOSOMAL SUBUNIT PROTEIN UL2M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 translation#GO:0006412;metabolic process#GO:0008152;mitochondrial gene expression#GO:0140053;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;mitochondrial translation#GO:0032543;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;cytosol#GO:0005829;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120840712|UniProtKB=A0ACM8EPB3 A0ACM8EPB3 LOC120840712 PTHR47961:SF12 DNA POLYMERASE THETA, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G05260)-RELATED HELICASE POLQ-LIKE ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824 response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA double-strand break processing#GO:0000729;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;double-strand break repair via homologous recombination#GO:0000724;double-strand break repair via single-strand annealing#GO:0045002;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;recombinational repair#GO:0000725;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120844443|UniProtKB=A0ACM8EYE6 A0ACM8EYE6 LOC120844443 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121835617|UniProtKB=A0ACM8FV37 A0ACM8FV37 LOC121835617 PTHR46473:SF28 GH08155P ELRR (EXTRACELLULAR LEUCINE-RICH REPEAT) ONLY IXOSC|EnsemblGenome=LOC115311272|UniProtKB=A0ACM8DQJ6 A0ACM8DQJ6 LOC115311272 PTHR46273:SF4 MYOSUPPRESSIN RECEPTOR 1, ISOFORM B-RELATED AT19640P signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115331236|UniProtKB=A0ACM8ECV1 A0ACM8ECV1 LOC115331236 PTHR13522:SF3 U6 SNRNA PHOSPHODIESTERASE 1 U6 SNRNA PHOSPHODIESTERASE 1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;3'-5' exonuclease activity#GO:0008408;RNA nuclease activity#GO:0004540;3'-5'-RNA exonuclease activity#GO:0000175;exonuclease activity#GO:0004527;nuclease activity#GO:0004518;hydrolase activity#GO:0016787 RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;snRNA metabolic process#GO:0016073;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;snRNA processing#GO:0016180;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115318153|UniProtKB=A0ACM8DXU0 A0ACM8DXU0 LOC115318153 PTHR13005:SF4 CYSTEINE-RICH HYDROPHOBIC DOMAIN PROTEIN BRAIN X-LINKED PROTEIN GOLGIN SUBFAMILY A MEMBER 7_ERF4 DOMAIN-CONTAINING PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8036664|UniProtKB=A0ACM8EEA0 A0ACM8EEA0 LOC8036664 PTHR21680:SF0 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 COILED-COIL DOMAIN-CONTAINING PROTEIN 124 transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115329102|UniProtKB=A0ACM8E908 A0ACM8E908 LOC115329102 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041023|UniProtKB=A0ACM8DRX7 A0ACM8DRX7 ITP PTHR35981:SF2 ION TRANSPORT PEPTIDE, ISOFORM C ION TRANSPORT PEPTIDE, ISOFORM C rhythmic process#GO:0048511;circadian rhythm#GO:0007623 IXOSC|EnsemblGenome=LOC8050982|UniProtKB=A0ACM8E599 A0ACM8E599 Hmt4-20 PTHR12977:SF4 SUPPRESSOR OF VARIEGATION 4-20-RELATED HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B-RELATED IXOSC|EnsemblGenome=LOC120849237|UniProtKB=A0ACM8FSY6 A0ACM8FSY6 LOC120849237 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035495|UniProtKB=A0ACM8ETK3 A0ACM8ETK3 LOC8035495 PTHR46075:SF2 CHIMERIN FAMILY MEMBER RHO GTPASE ACTIVATING PROTEIN AT 5A, ISOFORM A enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 IXOSC|EnsemblGenome=LOC8036874|UniProtKB=A0ACM8DW39 A0ACM8DW39 LOC8036874 PTHR12265:SF30 TRANSMEMBRANE PROTEIN 53 TRANSMEMBRANE PROTEIN 53 IXOSC|EnsemblGenome=LOC8030698|UniProtKB=A0ACM8DHE9 A0ACM8DHE9 Arv1 PTHR14467:SF0 ARV1 PROTEIN ARV1 lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;gene expression#GO:0010467;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8034422|UniProtKB=A0ACM8DT71 A0ACM8DT71 Galphai PTHR10218:SF227 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA I SUBUNIT molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154 cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494 G-protein#PC00020;heterotrimeric G-protein#PC00117 Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;Opioid proenkephalin pathway#P05915>G-protein#P05994;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gialpha#P00712;Opioid prodynorphin pathway#P05916>G-protein#P06002;PI3 kinase pathway#P00048>Galpha#P01199;Enkephalin release#P05913>G-Protein (i)#P05974 IXOSC|EnsemblGenome=LOC8029423|UniProtKB=A0ACM8DPF9 A0ACM8DPF9 LOC8029423 PTHR47533:SF4 PROTEIN CBG21859 AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323082|UniProtKB=A0ACM8ERX5 A0ACM8ERX5 LOC115323082 PTHR10334:SF609 CYSTEINE-RICH SECRETORY PROTEIN-RELATED EXTRACELLULAR PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G12350)-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8030434|UniProtKB=A0ACM8G6L0 A0ACM8G6L0 LOC8030434 PTHR23070:SF255 BCS1 AAA-TYPE ATPASE MITOCHONDRIAL CHAPERONE BCS1 protein localization to mitochondrion#GO:0070585;protein-containing complex assembly#GO:0065003;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;localization within membrane#GO:0051668;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;inner mitochondrial membrane organization#GO:0007007;mitochondrial membrane organization#GO:0007006;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;mitochondrial respiratory chain complex III assembly#GO:0034551;membrane organization#GO:0061024;mitochondrion organization#GO:0007005;mitochondrial respiratory chain complex assembly#GO:0033108;cellular component assembly#GO:0022607;protein insertion into membrane#GO:0051205;cytochrome complex assembly#GO:0017004;protein-containing complex organization#GO:0043933;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115318487|UniProtKB=A0ACM8F2U7 A0ACM8F2U7 LOC115318487 PTHR43767:SF1 LONG-CHAIN-FATTY-ACID--COA LIGASE NONRIBOSOMAL PEPTIDE SYNTHASE PES1 (EUROFUNG)-RELATED ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040904|UniProtKB=A0ACM8EBH6 A0ACM8EBH6 LOC8040904 PTHR12214:SF0 GC-RICH SEQUENCE DNA-BINDING FACTOR LD29489P intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8040843|UniProtKB=A0ACM8ECM0 A0ACM8ECM0 Sobp PTHR23186:SF4 RETINOIC ACID-INDUCED PROTEIN 2 GH22790P anatomical structure development#GO:0048856;animal organ development#GO:0048513;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC115319303|UniProtKB=A0ACM8FBU5 A0ACM8FBU5 LOC115319303 PTHR46207:SF1 PROTEIN RCC2 PROTEIN RCC2 small GTPase binding#GO:0031267;protein binding#GO:0005515;binding#GO:0005488;enzyme binding#GO:0019899 regulation of chromosome segregation#GO:0051983;localization#GO:0051179;intracellular protein localization#GO:0008104;protein localization to kinetochore#GO:0034501;macromolecule localization#GO:0033036;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;positive regulation of cell cycle process#GO:0090068;regulation of cellular process#GO:0050794;protein localization to organelle#GO:0033365;positive regulation of cell cycle#GO:0045787;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726 membrane#GO:0016020;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8031773|UniProtKB=A0ACM8FGR4 A0ACM8FGR4 LOC8031773 PTHR12027:SF91 WNT RELATED PROTO-ONCOGENE WNT-1 frizzled binding#GO:0005109;G protein-coupled receptor binding#GO:0001664;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;cytokine activity#GO:0005125;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 anatomical structure development#GO:0048856;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;system development#GO:0048731;cell fate commitment#GO:0045165;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell differentiation#GO:0030154;Wnt signaling pathway#GO:0016055;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;cell surface receptor signaling pathway#GO:0007166;neuron differentiation#GO:0030182;developmental process#GO:0032502;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 Angiogenesis#P00005>Wnt#P00206;Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 IXOSC|EnsemblGenome=LOC8035299|UniProtKB=A0ACM8DUW5 A0ACM8DUW5 Pli PTHR12098:SF2 E3 UBIQUITIN-PROTEIN LIGASE PELLINO-RELATED PROTEIN PELLINO transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;acyltransferase activity#GO:0016746;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein modification process#GO:0036211 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120838434|UniProtKB=A0ACM8EKL1 A0ACM8EKL1 LOC120838434 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839873|UniProtKB=A0ACM8EMY5 A0ACM8EMY5 LOC120839873 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8033467|UniProtKB=A0ACM8DXR6 A0ACM8DXR6 LOC8033467 PTHR12770:SF31 RUS1 FAMILY PROTEIN C16ORF58 RUS FAMILY MEMBER 1 IXOSC|EnsemblGenome=LOC120849846|UniProtKB=A0ACM8F8L4 A0ACM8F8L4 LOC120849846 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8051347|UniProtKB=A0ACM8FTD4 A0ACM8FTD4 LOC8051347 PTHR11304:SF29 EPHRIN EPHRIN protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 multicellular organismal process#GO:0032501;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;axon guidance#GO:0007411;axon development#GO:0061564;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;ephrin receptor signaling pathway#GO:0048013;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;system development#GO:0048731;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;neuron projection development#GO:0031175;signal transduction#GO:0007165;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cell projection morphogenesis#GO:0048858;neuron differentiation#GO:0030182;cell surface receptor signaling pathway#GO:0007166;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell differentiation#GO:0030154;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell morphogenesis#GO:0000902;signaling#GO:0023052;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;neuron development#GO:0048666;axonogenesis#GO:0007409;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 intercellular signal molecule#PC00207;membrane-bound signaling molecule#PC00152 IXOSC|EnsemblGenome=LOC8036984|UniProtKB=A0ACM8F3W1 A0ACM8F3W1 LOC8036984 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8036565|UniProtKB=A0ACM8E7W6 A0ACM8E7W6 LOC8036565 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8053082|UniProtKB=A0ACM8DLK4 A0ACM8DLK4 LOC8053082 PTHR46186:SF2 CYSTATIN CYSTATIN-RELATED peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414;molecular function inhibitor activity#GO:0140678;cysteine-type endopeptidase inhibitor activity#GO:0004869;enzyme regulator activity#GO:0030234;enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;extracellular region#GO:0005576;vesicle#GO:0031982 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8041236|UniProtKB=A0ACM8E6J1 A0ACM8E6J1 LOC8041236 PTHR45623:SF17 CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED ATP-DEPENDENT CHROMATIN REMODELER MIT1 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity, acting on DNA#GO:0140097;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;protein binding#GO:0005515;ATP-dependent activity, acting on DNA#GO:0008094;histone binding#GO:0042393;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;catalytic activity, acting on a nucleic acid#GO:0140640;ribonucleoside triphosphate phosphatase activity#GO:0017111;chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;ATP hydrolysis activity#GO:0016887;DNA binding#GO:0003677;hydrolase activity#GO:0016787 cellular process#GO:0009987;cellular component organization#GO:0016043;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121833228|UniProtKB=A0ACM8FIP1 A0ACM8FIP1 LOC121833228 PTHR10048:SF14 PHOSPHATIDYLINOSITOL KINASE LD28067P lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphatidylinositol kinase activity#GO:0052742;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;cell migration#GO:0016477;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;regulation of cellular process#GO:0050794;glycerolipid metabolic process#GO:0046486;response to stimulus#GO:0050896;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;p53 pathway feedback loops 2#P04398>PI3K#P04661;FGF signaling pathway#P00021>PI3K#P00640;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;Apoptosis signaling pathway#P00006>PI3K#P00310;PDGF signaling pathway#P00047>PI3K#P01168;EGF receptor signaling pathway#P00018>PI3K#P00557;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Angiogenesis#P00005>PI3K#P00236 IXOSC|EnsemblGenome=LOC8042239|UniProtKB=A0ACM8G8R4 A0ACM8G8R4 Marf1 PTHR14379:SF93 LIMKAIN B LKAP MEIOSIS REGULATOR AND MRNA STABILITY FACTOR 1 binding#GO:0005488;protein-containing complex binding#GO:0044877 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8042596|UniProtKB=A0ACM8DY25 A0ACM8DY25 LOC8042596 PTHR19143:SF327 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FI21813P1-RELATED extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC115324712|UniProtKB=A0ACM8E472 A0ACM8E472 LOC115324712 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028682|UniProtKB=A0ACM8F6D9 A0ACM8F6D9 LOC8028682 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121836077|UniProtKB=A0ACM8FX68 A0ACM8FX68 LOC121836077 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331934|UniProtKB=A0ACM8ELW4 A0ACM8ELW4 LOC115331934 PTHR33198:SF22 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041209|UniProtKB=A0ACM8DKM7 A0ACM8DKM7 LOC8041209 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC8026038|UniProtKB=A0ACM8DW51 A0ACM8DW51 LOC8026038 PTHR12400:SF51 INOSITOL POLYPHOSPHATE KINASE INOSITOL POLYPHOSPHATE MULTIKINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, alcohol group as acceptor#GO:0016773 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;phosphorus metabolic process#GO:0006793;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;organophosphate biosynthetic process#GO:0090407 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 kinase#PC00137 IXOSC|EnsemblGenome=LOC8026507|UniProtKB=A0ACM8EUZ0 A0ACM8EUZ0 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8040757|UniProtKB=A0ACM8DH36 A0ACM8DH36 LOC8040757 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;UDP-xylosyltransferase activity#GO:0035252;pentosyltransferase activity#GO:0016763;UDP-glycosyltransferase activity#GO:0008194;xylosyltransferase activity#GO:0042285;glycosyltransferase activity#GO:0016757 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238 IXOSC|EnsemblGenome=ISCI024787|UniProtKB=Q4PMB3 Q4PMB3 RpS4 PTHR11581:SF0 30S/40S RIBOSOMAL PROTEIN S4 RIBOSOMAL PROTEIN S4 Y1-RELATED structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;cytosolic small ribosomal subunit#GO:0022627;ribonucleoprotein complex#GO:1990904;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115329810|UniProtKB=A0ACM8FZ74 A0ACM8FZ74 LOC115329810 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121833327|UniProtKB=A0ACM8FK63 A0ACM8FK63 LOC121833327 PTHR46599:SF9 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED 4-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8053881|UniProtKB=A0ACM8E2R0 A0ACM8E2R0 LOC8053881 PTHR10130:SF0 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR PEX5 PEROXISOMAL TARGETING SIGNAL 1 RECEPTOR signal sequence receptor activity#GO:0005048;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 peroxisome organization#GO:0007031;cellular localization#GO:0051641;transmembrane transport#GO:0055085;localization#GO:0051179;peroxisomal transport#GO:0043574;protein transport#GO:0015031;cellular component organization#GO:0016043;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;peroxisome#GO:0005777;cytosol#GO:0005829;microbody#GO:0042579 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120846708|UniProtKB=A0ACM8F275 A0ACM8F275 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053559|UniProtKB=A0ACM8DL79 A0ACM8DL79 CstF64 PTHR45735:SF2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 CLEAVAGE STIMULATION FACTOR SUBUNIT 2 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA processing factor#PC00147;mRNA polyadenylation factor#PC00146;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121837183|UniProtKB=A0ACM8G2A2 A0ACM8G2A2 LOC121837183 PTHR46289:SF20 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED ZINC FINGER MYM-TYPE CONTAINING 1 IXOSC|EnsemblGenome=LOC8039687|UniProtKB=A0ACM8DKF0 A0ACM8DKF0 LOC8039687 PTHR10472:SF1 D-TYROSYL-TRNA TYR DEACYLASE D-AMINOACYL-TRNA DEACYLASE 2 catalytic activity, acting on a tRNA#GO:0140101;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;catalytic activity, acting on RNA#GO:0140098;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;deacylase activity#GO:0160215;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120838876|UniProtKB=A0ACM8EKX2 A0ACM8EKX2 LOC120838876 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121834707|UniProtKB=A0ACM8FQR7 A0ACM8FQR7 PTHR22948:SF79 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120839693|UniProtKB=A0ACM8ENF6 A0ACM8ENF6 LOC120839693 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115311148|UniProtKB=A0ACM8EQL7 A0ACM8EQL7 LOC115311148 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8025822|UniProtKB=A0ACM8FF10 A0ACM8FF10 PTHR14094:SF9 SIGNAL RECOGNITION PARTICLE 72 SIGNAL RECOGNITION PARTICLE SUBUNIT SRP72 binding#GO:0005488;nucleic acid binding#GO:0003676;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;RNA binding#GO:0003723;ribonucleoprotein complex binding#GO:0043021 establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein targeting#GO:0006605;establishment of protein localization to endoplasmic reticulum#GO:0072599;protein targeting to membrane#GO:0006612;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;localization within membrane#GO:0051668;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of protein localization to organelle#GO:0072594;localization#GO:0051179;protein targeting to ER#GO:0045047 signal recognition particle, endoplasmic reticulum targeting#GO:0005786;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 IXOSC|EnsemblGenome=LOC120845324|UniProtKB=A0ACM8F0I2 A0ACM8F0I2 LOC120845324 PTHR21261:SF2 BEAT PROTEIN RE31221P intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8029368|UniProtKB=A0ACM8DZG0 A0ACM8DZG0 LOC8029368 PTHR11132:SF250 SOLUTE CARRIER FAMILY 35 SOLUTE CARRIER FAMILY 35 MEMBER E3 active transmembrane transporter activity#GO:0022804;antiporter activity#GO:0015297;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;nucleobase-containing compound transmembrane transporter activity#GO:0015932;organophosphate ester transmembrane transporter activity#GO:0015605;nucleotide-sugar transmembrane transporter activity#GO:0005338;carbohydrate derivative transmembrane transporter activity#GO:1901505 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8052869|UniProtKB=A0ACM8DSA8 A0ACM8DSA8 LOC8052869 PTHR21437:SF1 WIDE AWAKE WIDE AWAKE mitotic cell cycle process#GO:1903047;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;establishment of localization in cell#GO:0051649;establishment of spindle localization#GO:0051293;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;regulation of establishment or maintenance of cell polarity#GO:0032878;establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;localization#GO:0051179;spindle localization#GO:0051653;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;regulation of biological process#GO:0050789;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 IXOSC|EnsemblGenome=LOC8042066|UniProtKB=A0ACM8DKS8 A0ACM8DKS8 LOC8042066 PTHR21275:SF1 RWD DOMAIN-CONTAINING PROTEIN 4 RWD DOMAIN-CONTAINING PROTEIN 4 IXOSC|EnsemblGenome=LOC115322907|UniProtKB=A0ACM8E3S0 A0ACM8E3S0 LOC115322907 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324607|UniProtKB=A0ACM8E512 A0ACM8E512 LOC115324607 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED catalytic activity#GO:0003824;acetyltransferase activity#GO:0016407;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 cellular process#GO:0009987;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 microbody#GO:0042579;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;acyltransferase#PC00042 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC120841486|UniProtKB=A0ACM8ERQ9 A0ACM8ERQ9 LOC120841486 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8032157|UniProtKB=A0ACM8ELT0 A0ACM8ELT0 LOC8032157 PTHR10003:SF71 SUPEROXIDE DISMUTASE CU-ZN -RELATED EXTRACELLULAR SUPEROXIDE DISMUTASE [CU-ZN]-RELATED antioxidant activity#GO:0016209;catalytic activity#GO:0003824;copper ion binding#GO:0005507;oxidoreductase activity#GO:0016491;transition metal ion binding#GO:0046914;ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;cation binding#GO:0043169;metal ion binding#GO:0046872 response to oxidative stress#GO:0006979;superoxide metabolic process#GO:0006801;cellular response to chemical stress#GO:0062197;response to reactive oxygen species#GO:0000302;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152;cellular response to oxidative stress#GO:0034599;response to chemical#GO:0042221;cellular response to toxic substance#GO:0097237;detoxification#GO:0098754;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to oxygen-containing compound#GO:1901701;cellular oxidant detoxification#GO:0098869;cellular response to chemical stimulus#GO:0070887;cellular detoxification#GO:1990748;response to oxygen-containing compound#GO:1901700;cellular response to stress#GO:0033554;response to toxic substance#GO:0009636;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121838210|UniProtKB=A0ACM8G775 A0ACM8G775 LOC121838210 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331198|UniProtKB=A0ACM8ECU5 A0ACM8ECU5 LOC115331198 PTHR47241:SF4 FINGER PROTEIN, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8029474|UniProtKB=A0ACM8FIR3 A0ACM8FIR3 LOC8029474 PTHR22736:SF2 COILED-COIL DOMAIN-CONTAINING PROTEIN 66 COILED-COIL DOMAIN CONTAINING 66 binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;cell projection assembly#GO:0030031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782 membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;microtubule#GO:0005874;intracellular organelle#GO:0043229;cilium#GO:0005929;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8040184|UniProtKB=A0ACM8EIL3 A0ACM8EIL3 GrlHz PTHR38337:SF1 AGAP010540-PA GUSTATORY RECEPTOR-LIKE HOLOZOA, ISOFORM C IXOSC|EnsemblGenome=LOC115312026|UniProtKB=A0ACM8F9I3 A0ACM8F9I3 LOC115312026 PTHR23235:SF189 KRUEPPEL-LIKE TRANSCRIPTION FACTOR C2H2-TYPE DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8036186|UniProtKB=A0ACM8DVH4 A0ACM8DVH4 beta-Spec PTHR11915:SF462 SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN SPECTRIN BETA CHAIN binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;actin filament-based process#GO:0030029;anatomical structure development#GO:0048856;system development#GO:0048731;neuron development#GO:0048666;cellular component organization#GO:0016043;cell differentiation#GO:0030154;actin cytoskeleton organization#GO:0030036;cell development#GO:0048468;neuron differentiation#GO:0030182;developmental process#GO:0032502;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;organelle organization#GO:0006996;cellular process#GO:0009987;multicellular organismal process#GO:0032501;cytoskeleton organization#GO:0007010;nervous system development#GO:0007399 cytoskeleton#GO:0005856;membraneless organelle#GO:0043228;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cell projection#GO:0042995 actin or actin-binding cytoskeletal protein#PC00041 IXOSC|EnsemblGenome=LOC8041453|UniProtKB=A0ACM8E753 A0ACM8E753 LOC8041453 PTHR10947:SF3 PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN AND LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 47 catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;ligase activity#GO:0016874;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101 metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;translation#GO:0006412;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120845195|UniProtKB=A0ACM8F022 A0ACM8F022 LOC120845195 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833185|UniProtKB=A0ACM8FJJ3 A0ACM8FJJ3 LOC121833185 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;glucosidase activity#GO:0015926;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;alpha-glucosidase activity#GO:0090599 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC8040394|UniProtKB=A0ACM8DKI4 A0ACM8DKI4 EMRE PTHR33904:SF1 ESSENTIAL MCU REGULATOR, MITOCHONDRIAL ESSENTIAL MCU REGULATOR, MITOCHONDRIAL monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;cellular process#GO:0009987;mitochondrial calcium ion transmembrane transport#GO:0006851;monoatomic ion homeostasis#GO:0050801;calcium ion transport#GO:0006816;cellular homeostasis#GO:0019725;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;establishment of localization#GO:0051234;chemical homeostasis#GO:0048878;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;metal ion transport#GO:0030001;homeostatic process#GO:0042592;mitochondrial calcium ion homeostasis#GO:0051560;intracellular monoatomic ion homeostasis#GO:0006873;calcium ion transmembrane transport#GO:0070588;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074 cytoplasm#GO:0005737;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;organelle membrane#GO:0031090;transporter complex#GO:1990351;cation channel complex#GO:0034703;inner mitochondrial membrane protein complex#GO:0098800;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;calcium channel complex#GO:0034704;organelle envelope#GO:0031967;membrane protein complex#GO:0098796;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transmembrane transporter complex#GO:1902495;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115309409|UniProtKB=A0ACM8EWJ5 A0ACM8EWJ5 LOC115309409 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8052599|UniProtKB=A0ACM8EEM7 A0ACM8EEM7 LOC8052599 PTHR46531:SF1 ZINC TRANSPORTER 6 ZINC TRANSPORTER 6 metal ion transport#GO:0030001;zinc ion transport#GO:0006829;transport#GO:0006810;transition metal ion transport#GO:0000041;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 transporter#PC00227 IXOSC|EnsemblGenome=LOC120837551|UniProtKB=A0ACM8FQD7 A0ACM8FQD7 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115310223|UniProtKB=A0ACM8DPP5 A0ACM8DPP5 rempA PTHR15722:SF7 IFT140/172-RELATED INTRAFLAGELLAR TRANSPORT PROTEIN 140 HOMOLOG cellular component organization#GO:0016043;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;intraciliary retrograde transport#GO:0035721;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234 ciliary basal body#GO:0036064;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;intraciliary transport particle A#GO:0030991;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ciliary plasm#GO:0097014;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;cilium#GO:0005929;intraciliary transport particle#GO:0030990;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;axoneme#GO:0005930;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;organelle#GO:0043226 structural protein#PC00211 IXOSC|EnsemblGenome=LOC8032223|UniProtKB=A0ACM8DWJ9 A0ACM8DWJ9 LOC8032223 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887;response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular response to stimulus#GO:0051716;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115318005|UniProtKB=A0ACM8FUA7 A0ACM8FUA7 LOC115318005 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8052565|UniProtKB=A0ACM8E9T2 A0ACM8E9T2 LOC8052565 PTHR19307:SF14 TUMOR PROTEIN D52 TUMOR PROTEIN D52 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8030815|UniProtKB=A0ACM8G5K9 A0ACM8G5K9 LOC8030815 PTHR24131:SF10 APOPTOSIS-STIMULATING OF P53 PROTEIN ANKYRIN-REPEAT, SH3-DOMAIN, AND PROLINE-RICH-REGION CONTAINING PROTEIN, ISOFORM B binding#GO:0005488;protein binding#GO:0005515 biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;apoptotic signaling pathway#GO:0097190;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intrinsic apoptotic signaling pathway by p53 class mediator#GO:0072332;cell death#GO:0008219;apoptotic process#GO:0006915;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;programmed cell death#GO:0012501;intracellular signal transduction#GO:0035556;intrinsic apoptotic signaling pathway#GO:0097193;cell communication#GO:0007154;signal transduction by p53 class mediator#GO:0072331 intracellular organelle#GO:0043229;adherens junction#GO:0005912;membrane-bounded organelle#GO:0043227;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;cell junction#GO:0030054;nucleus#GO:0005634;cell-cell junction#GO:0005911;perinuclear region of cytoplasm#GO:0048471;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8043066|UniProtKB=A0ACM8E704 A0ACM8E704 PTHR12312:SF16 TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED TWISTED GASTRULATION PROTEIN HOMOLOG 1-A-RELATED regulation of biological process#GO:0050789;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of BMP signaling pathway#GO:0030510;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 SCW signaling pathway#P06216>TSG#P06330;DPP-SCW signaling pathway#P06212>TSG#P06258;BMP/activin signaling pathway-drosophila#P06211>TSG#P06242;DPP signaling pathway#P06213>TSG#P06287 IXOSC|EnsemblGenome=LOC115333028|UniProtKB=A0ACM8EFA2 A0ACM8EFA2 LOC115333028 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8025858|UniProtKB=A0ACM8DGJ4 A0ACM8DGJ4 LOC8025858 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121835568|UniProtKB=A0ACM8FUW7 A0ACM8FUW7 LOC121835568 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8027875|UniProtKB=A0ACM8E3A2 A0ACM8E3A2 AcCoAS PTHR24095:SF244 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;nucleobase-containing small molecule metabolic process#GO:0055086;acyl-CoA metabolic process#GO:0006637;nucleoside phosphate biosynthetic process#GO:1901293;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;purine-containing compound biosynthetic process#GO:0072522;acetyl-CoA metabolic process#GO:0006084 ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 IXOSC|EnsemblGenome=LOC121835996|UniProtKB=A0ACM8FXI3 A0ACM8FXI3 LOC121835996 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318180|UniProtKB=A0ACM8FJU6 A0ACM8FJU6 LOC115318180 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8024135|UniProtKB=A0ACM8E4R1 A0ACM8E4R1 LOC8024135 PTHR10288:SF356 KH DOMAIN CONTAINING RNA BINDING PROTEIN HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of RNA splicing#GO:0043484;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311 organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120841161|UniProtKB=A0ACM8ER35 A0ACM8ER35 LOC120841161 PTHR24250:SF27 CHYMOTRYPSIN-RELATED PANCREATIC ELASTASE II hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protein modifying enzyme#PC00260;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8034722|UniProtKB=A0ACM8DXU2 A0ACM8DXU2 Set8 PTHR46167:SF1 N-LYSINE METHYLTRANSFERASE KMT5A N-LYSINE METHYLTRANSFERASE KMT5A lysine N-methyltransferase activity#GO:0016278;histone modifying activity#GO:0140993;protein-lysine N-methyltransferase activity#GO:0016279;histone methyltransferase activity#GO:0042054;N-methyltransferase activity#GO:0008170;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;catalytic activity, acting on a protein#GO:0140096;protein methyltransferase activity#GO:0008276;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;chromosome condensation#GO:0030261;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;chromosome organization#GO:0051276;regulation of gene expression#GO:0010468;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;chromosome#GO:0005694;nucleus#GO:0005634 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8030479|UniProtKB=A0ACM8FBX3 A0ACM8FBX3 LOC8030479 PTHR11129:SF2 PROTEIN FARNESYLTRANSFERASE ALPHA SUBUNIT/RAB GERANYLGERANYL TRANSFERASE ALPHA SUBUNIT GERANYLGERANYL TRANSFERASE TYPE-2 SUBUNIT ALPHA prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096 vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;Golgi vesicle transport#GO:0048193;transport#GO:0006810;intracellular transport#GO:0046907 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;transferase complex#GO:1990234;catalytic complex#GO:1902494 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8034904|UniProtKB=A0ACM8F1T5 A0ACM8F1T5 LOC8034904 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC8027162|UniProtKB=A0ACM8DIS7 A0ACM8DIS7 PTHR13512:SF2 MEDIATOR COMPLEX SUBUNIT 28 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 28 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;mediator complex#GO:0016592;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031;general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC115325866|UniProtKB=A0ACM8ESH0 A0ACM8ESH0 LOC115325866 PTHR11532:SF84 PROTEASE M14 CARBOXYPEPTIDASE CARBOXYPEPTIDASE M catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metalloexopeptidase activity#GO:0008235;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;carboxypeptidase activity#GO:0004180;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;peptide metabolic process#GO:0006518;primary metabolic process#GO:0044238;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190 IXOSC|EnsemblGenome=LOC120842623|UniProtKB=A0ACM8EU85 A0ACM8EU85 LOC120842623 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121047197|UniProtKB=A0ACM8FEH1 A0ACM8FEH1 LOC121047197 PTHR11388:SF100 ORGANIC ANION TRANSPORTER SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER transporter#PC00227 IXOSC|EnsemblGenome=LOC8052432|UniProtKB=A0ACM8DLN3 A0ACM8DLN3 LOC8052432 PTHR45842:SF12 SYNAPTIC ADHESION-LIKE MOLECULE SALM TIR DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC121048219|UniProtKB=A0ACM8FYD2 A0ACM8FYD2 LOC121048219 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8024038|UniProtKB=A0ACM8F3R8 A0ACM8F3R8 LOC8024038 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121048111|UniProtKB=A0ACM8FGA4 A0ACM8FGA4 LOC121048111 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850141|UniProtKB=A0ACM8FBM3 A0ACM8FBM3 LOC120850141 PTHR22930:SF269 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837847|UniProtKB=A0ACM8G6P8 A0ACM8G6P8 LOC121837847 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115323845|UniProtKB=A0ACM8FVP2 A0ACM8FVP2 LOC115323845 PTHR22526:SF2 ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED ANAPHASE PROMOTING COMPLEX C SUBUNIT 15, PSEUDOGENE-RELATED regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;regulation of cell communication#GO:0010646;regulation of sister chromatid segregation#GO:0033045;regulation of cell cycle#GO:0051726;regulation of cell cycle phase transition#GO:1901987;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of mitotic sister chromatid segregation#GO:0033047;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of chromosome separation#GO:1905818;regulation of mitotic metaphase/anaphase transition#GO:0030071;regulation of nuclear division#GO:0051783;regulation of signal transduction#GO:0009966;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;regulation of chromosome organization#GO:0033044;regulation of response to stimulus#GO:0048583;regulation of chromosome segregation#GO:0051983 nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;protein-containing complex#GO:0032991;anaphase-promoting complex#GO:0005680;nucleus#GO:0005634;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear ubiquitin ligase complex#GO:0000152;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461 IXOSC|EnsemblGenome=LOC8052773|UniProtKB=A0ACM8FMD9 A0ACM8FMD9 PTHR12702:SF0 SEC15 EXOCYST COMPLEX COMPONENT 6 cellular process#GO:0009987;export from cell#GO:0140352;vesicle-mediated transport#GO:0016192;transport#GO:0006810;exocytosis#GO:0006887;secretion by cell#GO:0032940;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903 intracellular anatomical structure#GO:0005622;vesicle tethering complex#GO:0099023;exocyst#GO:0000145;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;cell cortex#GO:0005938 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120837060|UniProtKB=A0ACM8EH58 A0ACM8EH58 LOC120837060 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8042867|UniProtKB=A0ACM8EP53 A0ACM8EP53 LOC8042867 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8029574|UniProtKB=A0ACM8F4Z4 A0ACM8F4Z4 LOC8029574 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;active transmembrane transporter activity#GO:0022804 sodium ion transport#GO:0006814;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8033972|UniProtKB=A0ACM8E1W6 A0ACM8E1W6 LOC8033972 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8053615|UniProtKB=A0ACM8E2A6 A0ACM8E2A6 LOC8053615 PTHR11516:SF60 PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR PYRUVATE DEHYDROGENASE E1 COMPONENT SUBUNIT ALPHA oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;nucleoside phosphate biosynthetic process#GO:1901293;energy derivation by oxidation of organic compounds#GO:0015980;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;oxoacid metabolic process#GO:0043436;acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;aerobic respiration#GO:0009060;organophosphate biosynthetic process#GO:0090407;cellular respiration#GO:0045333;purine-containing compound metabolic process#GO:0072521;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;pyruvate metabolic process#GO:0006090;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;oxidoreductase complex#GO:1990204;membrane-enclosed lumen#GO:0031974;transferase complex#GO:1990234 oxidoreductase#PC00176;dehydrogenase#PC00092 Pyruvate metabolism#P02772>Pyruvate Dehydrogenase#P03133 IXOSC|EnsemblGenome=LOC120841403|UniProtKB=A0ACM8ESK9 A0ACM8ESK9 LOC120841403 PTHR11214:SF378 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,3-GALACTOSYLTRANSFERASE 4 glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC8040108|UniProtKB=A0ACM8EUY2 A0ACM8EUY2 PTHR23248:SF9 PHOSPHOLIPID SCRAMBLASE-RELATED PHOSPHOLIPID SCRAMBLASE lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;phospholipid scramblase activity#GO:0017128;transporter activity#GO:0005215;intramembrane lipid carrier activity#GO:0140303 lipid transport#GO:0006869;phospholipid translocation#GO:0045332;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;phospholipid transport#GO:0015914;biological regulation#GO:0065007;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;organophosphate ester transport#GO:0015748;plasma membrane phospholipid scrambling#GO:0017121;lipid translocation#GO:0034204;cellular component organization#GO:0016043;plasma membrane organization#GO:0007009;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8050868|UniProtKB=A0ACM8E6R1 A0ACM8E6R1 LOC8050868 PTHR24223:SF330 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 10 ATPase-coupled transmembrane transporter activity#GO:0042626;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;ATP-dependent activity#GO:0140657;xenobiotic transmembrane transporter activity#GO:0042910;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;cellular process#GO:0009987;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121047300|UniProtKB=A0ACM8FGW2 A0ACM8FGW2 LOC121047300 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039729|UniProtKB=A0ACM8E1V1 A0ACM8E1V1 LOC8039729 PTHR45695:SF38 LEUCOKININ RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 83 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121046418|UniProtKB=A0ACM8FWS9 A0ACM8FWS9 LOC121046418 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042168|UniProtKB=A0ACM8E7B8 A0ACM8E7B8 Kdm5 PTHR10694:SF148 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 5 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;oxidoreductase activity#GO:0016491;protein demethylase activity#GO:0140457;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8036895|UniProtKB=A0ACM8FYK5 A0ACM8FYK5 LOC8036895 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120849521|UniProtKB=A0ACM8FZV4 A0ACM8FZV4 LOC120849521 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC120836737|UniProtKB=A0ACM8EGM6 A0ACM8EGM6 LOC120836737 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115320677|UniProtKB=A0ACM8G7L5 A0ACM8G7L5 LOC115320677 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121045946|UniProtKB=A0ACM8G678 A0ACM8G678 LOC121045946 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC115311482|UniProtKB=A0ACM8EQC3 A0ACM8EQC3 LOC115311482 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 reductase#PC00198 IXOSC|EnsemblGenome=LOC115316096|UniProtKB=A0ACM8EGR6 A0ACM8EGR6 PTHR48036:SF6 SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED RNA-BINDING MOTIF PROTEIN 39A-RELATED protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021;binding#GO:0005488 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120846023|UniProtKB=A0ACM8F1A1 A0ACM8F1A1 LOC120846023 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323361|UniProtKB=A0ACM8EM72 A0ACM8EM72 LOC115323361 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8052092|UniProtKB=A0ACM8F9G7 A0ACM8F9G7 LOC8052092 PTHR20855:SF152 ADIPOR/PROGESTIN RECEPTOR-RELATED ADIPONECTIN RECEPTOR PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;response to cytokine#GO:0034097;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cellular response to cytokine stimulus#GO:0071345;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;cytokine-mediated signaling pathway#GO:0019221;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;response to peptide#GO:1901652 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121834851|UniProtKB=A0ACM8FRM8 A0ACM8FRM8 LOC121834851 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121046232|UniProtKB=A0ACM8FDF8 A0ACM8FDF8 LOC121046232 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849126|UniProtKB=A0ACM8F7H0 A0ACM8F7H0 LOC120849126 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC115332388|UniProtKB=A0ACM8G3A7 A0ACM8G3A7 LOC115332388 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034748|UniProtKB=A0ACM8E5N4 A0ACM8E5N4 cpb PTHR10619:SF0 F-ACTIN-CAPPING PROTEIN SUBUNIT BETA F-ACTIN-CAPPING PROTEIN SUBUNIT BETA ISOFORMS 1 AND 2 cytoskeletal protein binding#GO:0008092;actin filament binding#GO:0051015;actin binding#GO:0003779;binding#GO:0005488;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component organization#GO:0051128;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;cellular process#GO:0009987;regulation of protein-containing complex disassembly#GO:0043244;organelle organization#GO:0006996;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of actin filament depolymerization#GO:0030834;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;regulation of actin filament organization#GO:0110053;negative regulation of protein depolymerization#GO:1901880;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of actin filament polymerization#GO:0030833;regulation of actin filament-based process#GO:0032970;negative regulation of cellular process#GO:0048523;regulation of protein depolymerization#GO:1901879 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC8051328|UniProtKB=A0ACM8FQU3 A0ACM8FQU3 LOC8051328 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053526|UniProtKB=A0ACM8F2G9 A0ACM8F2G9 LOC8053526 PTHR46849:SF1 RCC1 DOMAIN-CONTAINING PROTEIN 1 RCC1 DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC120838220|UniProtKB=A0ACM8EJB2 A0ACM8EJB2 LOC120838220 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052676|UniProtKB=A0ACM8DMJ4 A0ACM8DMJ4 PTHR45697:SF3 ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 2-RELATED ADP-RIBOSYLATION FACTOR-LIKE PROTEIN 3 ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;nucleotide binding#GO:0000166;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630 IXOSC|EnsemblGenome=LOC115329142|UniProtKB=A0ACM8EAH2 A0ACM8EAH2 LOC115329142 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8029729|UniProtKB=A0ACM8EW36 A0ACM8EW36 LOC8029729 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836959|UniProtKB=A0ACM8EH74 A0ACM8EH74 LOC120836959 PTHR11717:SF7 LOW MOLECULAR WEIGHT PROTEIN TYROSINE PHOSPHATASE LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoprotein phosphatase activity#GO:0004721;protein tyrosine phosphatase activity#GO:0004725;hydrolase activity#GO:0016787 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8051942|UniProtKB=A0ACM8E005 A0ACM8E005 LOC8051942 PTHR24248:SF209 ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 5A ISOFORM X1 transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cell communication#GO:0007154;adrenergic receptor signaling pathway#GO:0071875;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8029799|UniProtKB=A0ACM8DQG4 A0ACM8DQG4 LOC8029799 PTHR31606:SF1 WW DOMAIN BINDING PROTEIN 2, ISOFORM E WW DOMAIN BINDING PROTEIN 2, ISOFORM E DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;transcription coregulator activity#GO:0003712;chromatin DNA binding#GO:0031490 positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8053565|UniProtKB=A0ACM8E901 A0ACM8E901 LOC8053565 PTHR21021:SF16 GAF/PUTATIVE CYTOSKELETAL PROTEIN TIP41-LIKE PROTEIN enzyme activator activity#GO:0008047;catalytic activity#GO:0003824;phosphatase regulator activity#GO:0019208;oxidoreductase activity#GO:0016491;molecular function regulator activity#GO:0098772;phosphatase activator activity#GO:0019211;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;protein phosphatase regulator activity#GO:0019888 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;TOR signaling#GO:0031929;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;regulation of biological process#GO:0050789;signal transduction#GO:0007165 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC121838248|UniProtKB=A0ACM8G8C4 A0ACM8G8C4 LOC121838248 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8051414|UniProtKB=A0ACM8DLT7 A0ACM8DLT7 LOC8051414 PTHR34753:SF1 TELOMERASE RNA COMPONENT INTERACTING RNASE TELOMERASE RNA COMPONENT-INTERACTING RNASE exonuclease activity#GO:0004527;hydrolase activity#GO:0016787;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;3'-5' exonuclease activity#GO:0008408 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8025290|UniProtKB=A0ACM8DJ46 A0ACM8DJ46 Ccm3 PTHR13250:SF1 TF-1 CELL APOPTOSIS RELATED PROTEIN-15 PROGRAMMED CELL DEATH PROTEIN 10 binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 cellular component organization or biogenesis#GO:0071840;Golgi organization#GO:0007030;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC115315828|UniProtKB=A0ACM8DVC0 A0ACM8DVC0 LOC115315828 PTHR11462:SF60 JUN TRANSCRIPTION FACTOR-RELATED TRANSCRIPTION FACTOR JRA sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 positive regulation of transcription by RNA polymerase II#GO:0045944;response to hormone#GO:0009725;positive regulation of biological process#GO:0048518;response to chemical#GO:0042221;positive regulation of macromolecule metabolic process#GO:0010604;response to lipid#GO:0033993;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;response to steroid hormone#GO:0048545;regulation of cell population proliferation#GO:0042127;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 transcription regulator complex#GO:0005667;protein-containing complex#GO:0032991 DNA-binding transcription factor#PC00218;basic leucine zipper transcription factor#PC00056 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>AP-1#P00838 IXOSC|EnsemblGenome=LOC115317348|UniProtKB=A0ACM8ESC4 A0ACM8ESC4 PTHR21411:SF0 APONTIC REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC8040832|UniProtKB=A0ACM8E0B2 A0ACM8E0B2 Crtc PTHR13589:SF15 CREB-REGULATED TRANSCRIPTION COACTIVATOR CREB-REGULATED TRANSCRIPTION COACTIVATOR, ISOFORM B transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription factor binding#GO:0008134;binding#GO:0005488;DNA-binding transcription factor binding#GO:0140297;transcription coactivator activity#GO:0003713;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;response to nitrogen compound#GO:1901698;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;cellular response to stimulus#GO:0051716;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of DNA-templated transcription#GO:0045893;cellular response to nitrogen compound#GO:1901699;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of cellular process#GO:0048522;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;response to oxygen-containing compound#GO:1901700;cellular response to chemical stimulus#GO:0070887;regulation of transcription by RNA polymerase II#GO:0006357;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;cellular response to oxygen-containing compound#GO:1901701 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8032857|UniProtKB=A0ACM8EI14 A0ACM8EI14 LOC8032857 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835433|UniProtKB=A0ACM8FUM5 A0ACM8FUM5 LOC121835433 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315220|UniProtKB=A0ACM8DV25 A0ACM8DV25 LOC115315220 PTHR24067:SF384 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN CONJUGATING ENZYME E2 M intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115323561|UniProtKB=A0ACM8E4C5 A0ACM8E4C5 LOC115323561 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8041312|UniProtKB=A0ACM8G125 A0ACM8G125 PDZ-GEF PTHR23113:SF249 GUANINE NUCLEOTIDE EXCHANGE FACTOR RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 6 molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 neuron projection development#GO:0031175;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;intracellular signaling cassette#GO:0141124;neuron differentiation#GO:0030182;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell development#GO:0048468;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;neuron development#GO:0048666;multicellular organismal process#GO:0032501;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;developmental process#GO:0032502;cellular developmental process#GO:0048869;neurogenesis#GO:0022008;cellular response to stimulus#GO:0051716;regulation of cellular process#GO:0050794;Ras protein signal transduction#GO:0007265;anatomical structure development#GO:0048856;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;system development#GO:0048731 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;cell periphery#GO:0071944;apical part of cell#GO:0045177;membrane#GO:0016020;apical plasma membrane#GO:0016324 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8024111|UniProtKB=A0ACM8DMV0 A0ACM8DMV0 LOC8024111 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;enzyme inhibitor activity#GO:0004857;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;peptidase regulator activity#GO:0061134;endopeptidase regulator activity#GO:0061135;peptidase inhibitor activity#GO:0030414 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC121837080|UniProtKB=A0ACM8G214 A0ACM8G214 LOC121837080 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315004|UniProtKB=A0ACM8DUI7 A0ACM8DUI7 LOC115315004 PTHR10609:SF28 BIOTINIDASE-RELATED CN HYDROLASE DOMAIN-CONTAINING PROTEIN-RELATED hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8026458|UniProtKB=A0ACM8G5N2 A0ACM8G5N2 Tmem63 PTHR13018:SF5 PROBABLE MEMBRANE PROTEIN DUF221-RELATED MECHANOSENSITIVE CATION CHANNEL TMEM63 ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;calcium-activated cation channel activity#GO:0005227;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic ion-gated channel activity#GO:0022839;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC120839665|UniProtKB=A0ACM8FMT1 A0ACM8FMT1 LOC120839665 PTHR12871:SF0 BETA-1,2-N-ACETYLGLUCOSAMINYLTRANSFERASE II ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE acetylglucosaminyltransferase activity#GO:0008375;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;biosynthetic process#GO:0009058 membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC120842766|UniProtKB=A0ACM8EUK6 A0ACM8EUK6 LOC120842766 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC8043237|UniProtKB=A0ACM8E8C5 A0ACM8E8C5 AIMP2 PTHR13438:SF2 AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONAL PROTEIN 2 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 protein-containing complex assembly#GO:0065003;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;protein-containing complex organization#GO:0043933;cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840 protein-containing complex#GO:0032991;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115322190|UniProtKB=A0ACM8FCC0 A0ACM8FCC0 LOC115322190 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841898|UniProtKB=A0ACM8ESN1 A0ACM8ESN1 LOC120841898 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8050585|UniProtKB=A0ACM8ELI1 A0ACM8ELI1 LOC8050585 PTHR11596:SF96 ALKALINE PHOSPHATASE ALKALINE PHOSPHATASE-RELATED hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC8033250|UniProtKB=A0ACM8F158 A0ACM8F158 beat-IIIb PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC115328875|UniProtKB=A0ACM8EPZ1 A0ACM8EPZ1 LOC115328875 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8038922|UniProtKB=A0ACM8FTI9 A0ACM8FTI9 LOC8038922 PTHR23194:SF16 PYGOPUS PROTEIN PYGOPUS transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;Wnt signaling pathway#GO:0016055;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;canonical Wnt signaling pathway#GO:0060070;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 Wnt signaling pathway#P00057>Pygo#P01464 IXOSC|EnsemblGenome=LOC8029098|UniProtKB=A0ACM8EEA7 A0ACM8EEA7 Idh3a PTHR11835:SF34 DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT ALPHA, MITOCHONDRIAL oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular process#GO:0009987;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;alcohol metabolic process#GO:0006066;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281 oxidoreductase#PC00176;dehydrogenase#PC00092 Leucine biosynthesis#P02749>3-Isopropylmalate dehydrogenase#P03001 IXOSC|EnsemblGenome=LOC120849226|UniProtKB=A0ACM8F8A1 A0ACM8F8A1 LOC120849226 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028194|UniProtKB=A0ACM8FGN9 A0ACM8FGN9 LOC8028194 PTHR19212:SF0 LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN LD07988P gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8026858|UniProtKB=A0ACM8DR92 A0ACM8DR92 GABPI PTHR22883:SF475 ZINC FINGER DHHC DOMAIN CONTAINING PROTEIN PALMITOYLTRANSFERASE ZDHHC23 catalytic activity, acting on a protein#GO:0140096;palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;protein targeting to membrane#GO:0006612;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;establishment of protein localization#GO:0045184;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;protein targeting#GO:0006605 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8052638|UniProtKB=A0ACM8DM27 A0ACM8DM27 LOC8052638 PTHR11036:SF127 SEMAPHORIN SEMAPHORIN-1A receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772;binding#GO:0005488;signaling receptor binding#GO:0005102;molecular function activator activity#GO:0140677;protein binding#GO:0005515 cell projection morphogenesis#GO:0048858;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;taxis#GO:0042330;response to chemical#GO:0042221;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;neuron projection development#GO:0031175;axonogenesis#GO:0007409;neuron development#GO:0048666;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;signaling#GO:0023052;cell development#GO:0048468;cell projection organization#GO:0030030;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;positive regulation of cell motility#GO:2000147;cellular component organization#GO:0016043;neuron projection guidance#GO:0097485;response to external stimulus#GO:0009605;positive regulation of locomotion#GO:0040017;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;developmental process#GO:0032502;regulation of cell migration#GO:0030334;neuron projection morphogenesis#GO:0048812;biological regulation#GO:0065007;plasma membrane bounded cell projection organization#GO:0120036;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;positive regulation of cellular process#GO:0048522;positive regulation of cell migration#GO:0030335;axon guidance#GO:0007411;axon development#GO:0061564;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;anatomical structure development#GO:0048856;chemotaxis#GO:0006935;locomotion#GO:0040011;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 membrane-bound signaling molecule#PC00152 IXOSC|EnsemblGenome=LOC8031060|UniProtKB=A0ACM8DTE0 A0ACM8DTE0 LOC8031060 PTHR24241:SF202 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR FREE FATTY ACID RECEPTOR 4 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;cell communication#GO:0007154;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8050504|UniProtKB=A0ACM8FTQ1 A0ACM8FTQ1 LOC8050504 PTHR47219:SF20 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE TBC1 DOMAIN FAMILY MEMBER 2B molecular function regulator activity#GO:0098772;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;small GTPase binding#GO:0031267;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;enzyme binding#GO:0019899;binding#GO:0005488 G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8023542|UniProtKB=A0ACM8DS63 A0ACM8DS63 mad2 PTHR11842:SF11 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2 MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of mitotic metaphase/anaphase transition#GO:0030071;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;biological regulation#GO:0065007;regulation of mitotic cell cycle#GO:0007346;cell communication#GO:0007154;regulation of mitotic sister chromatid segregation#GO:0033047;intracellular signal transduction#GO:0035556;negative regulation of chromosome organization#GO:2001251;regulation of cellular process#GO:0050794;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;negative regulation of cell cycle#GO:0045786;negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of sister chromatid segregation#GO:0033046;cellular process#GO:0009987;signal transduction#GO:0007165;mitotic spindle assembly checkpoint signaling#GO:0007094;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of cellular component organization#GO:0051128;response to stimulus#GO:0050896;regulation of sister chromatid segregation#GO:0033045;signaling#GO:0023052;regulation of cell cycle#GO:0051726;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;negative regulation of mitotic nuclear division#GO:0045839 kinetochore#GO:0000776;chromosome#GO:0005694;condensed chromosome, centromeric region#GO:0000779;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC8038498|UniProtKB=A0ACM8DK84 A0ACM8DK84 Srp14 PTHR12013:SF0 SIGNAL RECOGNITION PARTICLE 14 KD PROTEIN SIGNAL RECOGNITION PARTICLE 14 KDA PROTEIN intracellular protein transport#GO:0006886;transport#GO:0006810;protein transmembrane transport#GO:0071806;SRP-dependent cotranslational protein targeting to membrane#GO:0006614;protein targeting to membrane#GO:0006612;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;protein targeting to ER#GO:0045047;establishment of protein localization to organelle#GO:0072594;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of protein localization to endoplasmic reticulum#GO:0072599;localization within membrane#GO:0051668;protein transport#GO:0015031;localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein targeting#GO:0006605 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;signal recognition particle, endoplasmic reticulum targeting#GO:0005786;ribonucleoprotein complex#GO:1990904 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115326038|UniProtKB=A0ACM8E641 A0ACM8E641 LOC115326038 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115323066|UniProtKB=A0ACM8EQE7 A0ACM8EQE7 LOC115323066 PTHR36902:SF1 ENRICHED IN SURFACE-LABELED PROTEOME PROTEIN 9 LOLA-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314045|UniProtKB=A0ACM8G454 A0ACM8G454 LOC115314045 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC120840481|UniProtKB=A0ACM8G3B4 A0ACM8G3B4 LOC120840481 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038619|UniProtKB=A0ACM8DWW0 A0ACM8DWW0 LOC8038619 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115324254|UniProtKB=A0ACM8FIU9 A0ACM8FIU9 LOC115324254 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120835996|UniProtKB=A0ACM8F1N8 A0ACM8F1N8 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115308174|UniProtKB=A0ACM8DMR6 A0ACM8DMR6 ND-MLRQ PTHR14256:SF1 NADH-UBIQUINONE OXIDOREDUCTASE MLRQ SUBUNIT GEO09626P1 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120845313|UniProtKB=A0ACM8FGY1 A0ACM8FGY1 LOC120845313 PTHR46970:SF2 BASIC HELIX-LOOP-HELIX DOMAIN-CONTAINING PROTEIN USF3 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8028367|UniProtKB=A0ACM8E854 A0ACM8E854 LOC8028367 PTHR43323:SF2 3-HYDROXY-3-METHYLGLUTARYL COENZYME A SYNTHASE HYDROXYMETHYLGLUTARYL-COA SYNTHASE acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 purine-containing compound metabolic process#GO:0072521;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleobase-containing compound metabolic process#GO:0006139;nucleoside phosphate metabolic process#GO:0006753;small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;acetyl-CoA metabolic process#GO:0006084;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086 Cholesterol biosynthesis#P00014>Hydroxymethyl glutaryl CoA synthase#P00498 IXOSC|EnsemblGenome=LOC8035504|UniProtKB=A0ACM8DJU9 A0ACM8DJU9 LOC8035504 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;channel activity#GO:0015267 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 IXOSC|EnsemblGenome=LOC8051143|UniProtKB=A0ACM8E1F3 A0ACM8E1F3 LOC8051143 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8041026|UniProtKB=A0ACM8DGX5 A0ACM8DGX5 LOC8041026 PTHR14119:SF19 HYDROLASE ISOCHORISMATASE DOMAIN-CONTAINING PROTEIN 2 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8035630|UniProtKB=A0ACM8E2L7 A0ACM8E2L7 LOC8035630 PTHR12216:SF3 UROCANATE HYDRATASE UROCANATE HYDRATASE hydro-lyase activity#GO:0016836;lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;catalytic activity#GO:0003824 amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 hydratase#PC00120 IXOSC|EnsemblGenome=LOC8052759|UniProtKB=A0ACM8EC82 A0ACM8EC82 LOC8052759 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115322054|UniProtKB=A0ACM8EYF9 A0ACM8EYF9 LOC115322054 PTHR14166:SF17 SLIT-ROBO RHO GTPASE ACTIVATING PROTEIN RHO-GAP DOMAIN-CONTAINING PROTEIN enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 G-protein modulator#PC00022;GTPase-activating protein#PC00257 PDGF signaling pathway#P00047>Rho#P01174 IXOSC|EnsemblGenome=LOC121836045|UniProtKB=A0ACM8FWY1 A0ACM8FWY1 LOC121836045 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120843929|UniProtKB=A0ACM8EX62 A0ACM8EX62 LOC120843929 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8031110|UniProtKB=A0ACM8DUW9 A0ACM8DUW9 Trxr1 PTHR48105:SF21 THIOREDOXIN REDUCTASE 1-RELATED-RELATED THIOREDOXIN REDUCTASE 2, MITOCHONDRIAL antioxidant activity#GO:0016209;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;catalytic activity#GO:0003824;disulfide oxidoreductase activity#GO:0015036;protein-disulfide reductase activity#GO:0015035;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491 cell redox homeostasis#GO:0045454;homeostatic process#GO:0042592;cellular homeostasis#GO:0019725 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115319302|UniProtKB=A0ACM8F473 A0ACM8F473 LOC115319302 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8025444|UniProtKB=A0ACM8FI20 A0ACM8FI20 LOC8025444 PTHR46576:SF1 BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN BROMO ADJACENT HOMOLOGY DOMAIN-CONTAINING 1 PROTEIN chromatin binding#GO:0003682;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;negative regulation of cellular process#GO:0048523;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;heterochromatin formation#GO:0031507;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=ISCI011316|UniProtKB=Q4PM12 Q4PM12 RpL36 PTHR10114:SF0 60S RIBOSOMAL PROTEIN L36 LARGE RIBOSOMAL SUBUNIT PROTEIN EL36 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 biosynthetic process#GO:0009058;cytoplasmic translation#GO:0002181;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;translation#GO:0006412;metabolic process#GO:0008152 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC8039642|UniProtKB=A0ACM8E268 A0ACM8E268 LOC8039642 PTHR46756:SF13 TRANSGELIN GROWTH ARREST-SPECIFIC PROTEIN 2-LIKE protein binding#GO:0005515;protein-containing complex binding#GO:0044877;binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;supramolecular fiber organization#GO:0097435;actin filament organization#GO:0007015;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120841070|UniProtKB=A0ACM8EQG4 A0ACM8EQG4 LOC120841070 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8025192|UniProtKB=A0ACM8DQT6 A0ACM8DQT6 LOC8025192 PTHR19300:SF66 BETA-1,4-GALACTOSYLTRANSFERASE BETA1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE A catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;UDP-glycosyltransferase activity#GO:0008194;galactosyltransferase activity#GO:0008378 sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120843447|UniProtKB=A0ACM8G2I0 A0ACM8G2I0 LOC120843447 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832996|UniProtKB=A0ACM8FZZ3 A0ACM8FZZ3 LOC121832996 PTHR13161:SF15 SPLICING FACTOR SUPPRESSOR OF WHITE APRICOT SPLICING FACTOR, SUPPRESSOR OF WHITE-APRICOT HOMOLOG nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;protein-RNA complex organization#GO:0071826;alternative mRNA splicing, via spliceosome#GO:0000380;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;mRNA processing#GO:0006397;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;gene expression#GO:0010467;cellular component assembly#GO:0022607;mRNA splice site recognition#GO:0006376;RNA processing#GO:0006396;spliceosomal complex assembly#GO:0000245;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;ribonucleoprotein complex biogenesis#GO:0022613;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA splicing, via transesterification reactions#GO:0000375;protein-RNA complex assembly#GO:0022618;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;nucleoplasm#GO:0005654;organelle#GO:0043226;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 RNA processing factor#PC00147;RNA metabolism protein#PC00031;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120841021|UniProtKB=A0ACM8FNW0 A0ACM8FNW0 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8029685|UniProtKB=A0ACM8F2G4 A0ACM8F2G4 LOC8029685 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8027607|UniProtKB=A0ACM8ET94 A0ACM8ET94 LOC8027607 PTHR10117:SF54 TRANSIENT RECEPTOR POTENTIAL CHANNEL TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;channel activity#GO:0015267;transporter activity#GO:0005215;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;alcohol binding#GO:0043178;metal ion transmembrane transporter activity#GO:0046873;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;establishment of localization#GO:0051234;intracellular calcium ion homeostasis#GO:0006874;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;calcium ion transport#GO:0006816;calcium ion transmembrane transport#GO:0070588;intracellular monoatomic ion homeostasis#GO:0006873;regulation of cytosolic calcium ion concentration#GO:0051480;homeostatic process#GO:0042592;metal ion transport#GO:0030001;calcium ion homeostasis#GO:0055074;inorganic ion homeostasis#GO:0098771;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811 cation channel complex#GO:0034703;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;membrane protein complex#GO:0098796;membrane#GO:0016020;cell periphery#GO:0071944;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133 Alzheimer disease-presenilin pathway#P00004>Capacitative calcium channels#P00124 IXOSC|EnsemblGenome=LOC115317057|UniProtKB=A0ACM8FN94 A0ACM8FN94 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115324846|UniProtKB=A0ACM8FP44 A0ACM8FP44 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120836108|UniProtKB=A0ACM8EYK2 A0ACM8EYK2 LOC120836108 PTHR24056:SF334 CELL DIVISION PROTEIN KINASE CYCLIN-DEPENDENT KINASE 1 phosphotransferase activity, alcohol group as acceptor#GO:0016773;histone modifying activity#GO:0140993;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;cyclin-dependent protein kinase activity#GO:0097472;cyclin-dependent protein serine/threonine kinase activity#GO:0004693;histone kinase activity#GO:0035173;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 DNA damage response#GO:0006974;negative regulation of cell cycle process#GO:0010948;negative regulation of cellular process#GO:0048523;mitotic cell cycle process#GO:1903047;mitotic G2/M transition checkpoint#GO:0044818;regulation of mitotic cell cycle#GO:0007346;mitotic DNA integrity checkpoint signaling#GO:0044774;DNA integrity checkpoint signaling#GO:0031570;regulation of cell cycle G2/M phase transition#GO:1902749;biological regulation#GO:0065007;DNA damage checkpoint signaling#GO:0000077;mitotic cell cycle phase transition#GO:0044772;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;cellular response to stimulus#GO:0051716;mitotic DNA damage checkpoint signaling#GO:0044773;regulation of cell cycle phase transition#GO:1901987;mitotic cell cycle checkpoint signaling#GO:0007093;cell cycle#GO:0007049;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;G2/M transition of mitotic cell cycle#GO:0000086;negative regulation of cell cycle G2/M phase transition#GO:1902750;negative regulation of cell cycle#GO:0045786;signal transduction#GO:0007165;cell cycle G2/M phase transition#GO:0044839;cellular process#GO:0009987;response to stress#GO:0006950;regulation of cell cycle process#GO:0010564;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cellular response to stress#GO:0033554;negative regulation of mitotic cell cycle#GO:0045930;mitotic G2 DNA damage checkpoint signaling#GO:0007095;regulation of mitotic cell cycle phase transition#GO:1901990;regulation of biological process#GO:0050789;signal transduction in response to DNA damage#GO:0042770;cell cycle process#GO:0022402;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;signaling#GO:0023052;regulation of cell cycle#GO:0051726;response to stimulus#GO:0050896 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 p53 pathway#P00059>Cdc2#P04634 IXOSC|EnsemblGenome=LOC8029058|UniProtKB=A0ACM8DHJ4 A0ACM8DHJ4 LOC8029058 PTHR10281:SF4 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED NEUFERRICIN membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121046654|UniProtKB=A0ACM8FPF2 A0ACM8FPF2 PTHR23226:SF468 ZINC FINGER AND SCAN DOMAIN-CONTAINING SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115331848|UniProtKB=A0ACM8ELW6 A0ACM8ELW6 LOC115331848 PTHR11086:SF23 DEOXYCYTIDYLATE DEAMINASE-RELATED DEOXYCYTIDYLATE DEAMINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;carbohydrate derivative metabolic process#GO:1901135;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 deaminase#PC00088;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120850640|UniProtKB=A0ACM8FBA6 A0ACM8FBA6 LOC120850640 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8043265|UniProtKB=A0ACM8ECP9 A0ACM8ECP9 Rint1 PTHR13520:SF0 RAD50-INTERACTING PROTEIN 1 RINT-1 RAD50-INTERACTING PROTEIN 1 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;transport#GO:0006810;cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;vesicle tethering complex#GO:0099023;membrane-bounded organelle#GO:0043227;endoplasmic reticulum protein-containing complex#GO:0140534;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8034343|UniProtKB=A0ACM8EBQ0 A0ACM8EBQ0 LOC8034343 PTHR46451:SF1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 RAS-RESPONSIVE ELEMENT-BINDING PROTEIN 1 sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8026153|UniProtKB=A0ACM8G5D7 A0ACM8G5D7 LOC8026153 PTHR24379:SF126 KRAB AND ZINC FINGER DOMAIN-CONTAINING LD25880P C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120839157|UniProtKB=A0ACM8ELD0 A0ACM8ELD0 LOC120839157 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8052657|UniProtKB=A0ACM8E492 A0ACM8E492 LOC8052657 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8024275|UniProtKB=A0ACM8E6J0 A0ACM8E6J0 LOC8024275 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC121832844|UniProtKB=A0ACM8FB97 A0ACM8FB97 LOC121832844 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120849224|UniProtKB=A0ACM8F798 A0ACM8F798 LOC120849224 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8038033|UniProtKB=A0ACM8FYH0 A0ACM8FYH0 LOC8038033 PTHR10814:SF21 TRANSDUCIN-LIKE ENHANCER PROTEIN TRANSCRIPTION FACTOR UNC-37 transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription regulator activity#GO:0140110 regulation of canonical Wnt signaling pathway#GO:0060828;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of signal transduction#GO:0009968;negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217 Wnt signaling pathway#P00057>Transducin-like Enhance of Split 1-3#P01436 IXOSC|EnsemblGenome=LOC120842982|UniProtKB=A0ACM8EV38 A0ACM8EV38 LOC120842982 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033237|UniProtKB=A0ACM8E0L2 A0ACM8E0L2 LOC8033237 PTHR22762:SF131 ALPHA-GLUCOSIDASE LYSOSOMAL ALPHA-GLUCOSIDASE-LIKE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;glucosidase activity#GO:0015926;alpha-glucosidase activity#GO:0090599;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 glucosidase#PC00108 IXOSC|EnsemblGenome=LOC8032535|UniProtKB=A0ACM8E4S2 A0ACM8E4S2 LOC8032535 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120842020|UniProtKB=A0ACM8ESX2 A0ACM8ESX2 LOC120842020 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115318327|UniProtKB=A0ACM8DYF0 A0ACM8DYF0 LOC115318327 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115328747|UniProtKB=A0ACM8E9N1 A0ACM8E9N1 LOC115328747 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;monocarboxylic acid biosynthetic process#GO:0072330;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436 organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8050618|UniProtKB=A0ACM8G0R1 A0ACM8G0R1 LOC8050618 PTHR11537:SF294 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAW monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;voltage-gated potassium channel activity#GO:0005249;gated channel activity#GO:0022836;voltage-gated monoatomic ion channel activity#GO:0005244 metal ion transport#GO:0030001;action potential#GO:0001508;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;cellular process#GO:0009987;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391;transport#GO:0006810 plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;plasma membrane bounded cell projection#GO:0120025;distal axon#GO:0150034;neuronal cell body#GO:0043025;neuron projection terminus#GO:0044306;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;transmembrane transporter complex#GO:1902495;cell periphery#GO:0071944;membrane#GO:0016020;presynaptic membrane#GO:0042734;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;monoatomic ion channel complex#GO:0034702;plasma membrane region#GO:0098590;neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;axon terminus#GO:0043679;cell body#GO:0044297;postsynapse#GO:0098794;cell projection#GO:0042995;synapse#GO:0045202;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;postsynaptic membrane#GO:0045211;cell projection membrane#GO:0031253;presynapse#GO:0098793;neuron projection#GO:0043005;cell leading edge#GO:0031252;protein-containing complex#GO:0032991;synaptic membrane#GO:0097060;cation channel complex#GO:0034703;transporter complex#GO:1990351;cell junction#GO:0030054 voltage-gated ion channel#PC00241;ion channel#PC00133 IXOSC|EnsemblGenome=LOC120836761|UniProtKB=A0ACM8EGP6 A0ACM8EGP6 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8044051|UniProtKB=A0ACM8DN47 A0ACM8DN47 LOC8044051 PTHR12308:SF83 ANOCTAMIN ANOCTAMIN intramembrane lipid carrier activity#GO:0140303;transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;regulation of membrane lipid distribution#GO:0097035;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;transport#GO:0006810;lipid translocation#GO:0034204;organophosphate ester transport#GO:0015748;cellular component organization#GO:0016043;regulation of biological quality#GO:0065008;localization#GO:0051179;lipid localization#GO:0010876 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC121835810|UniProtKB=A0ACM8FVY0 A0ACM8FVY0 LOC121835810 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC8051089|UniProtKB=A0ACM8FTG4 A0ACM8FTG4 LOC8051089 PTHR11091:SF0 OXIDOREDUCTASE-RELATED MALATE DEHYDROGENASE metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 Allantoin degradation#P02725>Ureidoglycolate dehydrogenase#P02820;TCA cycle#P00051>Malate Dehydrogenase#P01270;Pyruvate metabolism#P02772>Malate Dehydrogenase#P03138 IXOSC|EnsemblGenome=LOC8023982|UniProtKB=A0ACM8DHT5 A0ACM8DHT5 LOC8023982 PTHR34341:SF1 TRANSMEMBRANE PROTEIN 107 TRANSMEMBRANE PROTEIN 107 organelle assembly#GO:0070925;cilium organization#GO:0044782;localization#GO:0051179;non-motile cilium assembly#GO:1905515;cilium assembly#GO:0060271;cellular component organization#GO:0016043;protein localization to cilium#GO:0061512;protein localization to organelle#GO:0033365;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;intracellular protein localization#GO:0008104;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cell projection assembly#GO:0030031;macromolecule localization#GO:0033036;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607 ciliary transition zone#GO:0035869;cilium#GO:0005929;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995 IXOSC|EnsemblGenome=LOC120836315|UniProtKB=A0ACM8FP99 A0ACM8FP99 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;lipid transport#GO:0006869 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121838194|UniProtKB=A0ACM8G836 A0ACM8G836 LOC121838194 PTHR24413:SF240 SPECKLE-TYPE POZ PROTEIN PROTEIN ROADKILL binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 regulation of proteolysis#GO:0030162;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;biological regulation#GO:0065007;proteasomal protein catabolic process#GO:0010498;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;regulation of biological process#GO:0050789;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8027881|UniProtKB=A0ACM8FL08 A0ACM8FL08 LOC8027881 PTHR12486:SF5 APRATAXIN-RELATED ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT3 DNA metabolism protein#PC00009;damaged DNA-binding protein#PC00086 IXOSC|EnsemblGenome=LOC115314280|UniProtKB=A0ACM8EX46 A0ACM8EX46 LOC115314280 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115319155|UniProtKB=A0ACM8DYU5 A0ACM8DYU5 LOC115319155 PTHR10177:SF347 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-B cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle#GO:0007049;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;protein kinase complex#GO:1902911;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 kinase activator#PC00138 p53 pathway#P00059>Cyclin B#P04614;Cell cycle#P00013>Cyclin B#P00486 IXOSC|EnsemblGenome=LOC115322569|UniProtKB=A0ACM8E2W4 A0ACM8E2W4 LOC115322569 PTHR11941:SF171 ENOYL-COA HYDRATASE-RELATED SD19268P lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 monocarboxylic acid catabolic process#GO:0072329;lipid catabolic process#GO:0016042;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;lipid modification#GO:0030258;fatty acid oxidation#GO:0019395;lipid metabolic process#GO:0006629;fatty acid beta-oxidation#GO:0006635;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;fatty acid catabolic process#GO:0009062;lipid oxidation#GO:0034440;oxoacid metabolic process#GO:0043436 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lyase#PC00144;hydratase#PC00120 IXOSC|EnsemblGenome=LOC121047026|UniProtKB=A0ACM8FFA7 A0ACM8FFA7 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038279|UniProtKB=A0ACM8FS68 A0ACM8FS68 sas PTHR11348:SF34 CONNECTIVE TISSUE GROWTH FACTOR-RELATED EPIDERMAL CELL SURFACE RECEPTOR-RELATED cell adhesion molecule binding#GO:0050839;signaling receptor binding#GO:0005102;binding#GO:0005488;integrin binding#GO:0005178;protein-containing complex binding#GO:0044877;protein binding#GO:0005515 positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of developmental process#GO:0050793;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;cell adhesion#GO:0007155;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;positive regulation of cell differentiation#GO:0045597 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207;growth factor#PC00112 IXOSC|EnsemblGenome=LOC120849787|UniProtKB=A0ACM8G768 A0ACM8G768 LOC120849787 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050865|UniProtKB=A0ACM8DLN6 A0ACM8DLN6 vito PTHR14577:SF0 NUCLEOLAR PROTEIN 12 NUCLEOLAR PROTEIN 12 binding#GO:0005488;nucleic acid binding#GO:0003676;rRNA binding#GO:0019843;RNA binding#GO:0003723 intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC8029660|UniProtKB=A0ACM8EE16 A0ACM8EE16 LOC8029660 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC115308372|UniProtKB=A0ACM8EW93 A0ACM8EW93 LOC115308372 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115316423|UniProtKB=A0ACM8EM99 A0ACM8EM99 LOC115316423 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8028952|UniProtKB=A0ACM8G0I7 A0ACM8G0I7 OSCP1 PTHR21439:SF0 OXIDORED-NITRO DOMAIN-CONTAINING PROTEIN PROTEIN OSCP1 plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115332829|UniProtKB=A0ACM8EEP5 A0ACM8EEP5 LOC115332829 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8053813|UniProtKB=A0ACM8E067 A0ACM8E067 LOC8053813 PTHR45781:SF1 AGAP000281-PA HMG BOX DOMAIN-CONTAINING PROTEIN binding#GO:0005488;nucleic acid binding#GO:0003676;chromatin DNA binding#GO:0031490;chromatin binding#GO:0003682;DNA binding#GO:0003677 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 IXOSC|EnsemblGenome=LOC115321330|UniProtKB=A0ACM8F923 A0ACM8F923 LOC115321330 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8041515|UniProtKB=A0ACM8DUB5 A0ACM8DUB5 LOC8041515 PTHR11225:SF4 NUCLEAR PORE COMPLEX PROTEIN NUP93 NUCLEOPORIN NUP93 DEAD EYE PROTEIN NUCLEAR PORE COMPLEX PROTEIN NUP93 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;gene expression#GO:0010467;metabolic process#GO:0008152;intracellular protein transport#GO:0006886;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;protein transport#GO:0015031;protein import into nucleus#GO:0006606;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;nucleobase-containing compound transport#GO:0015931;RNA transport#GO:0050658;protein localization to organelle#GO:0033365;RNA localization#GO:0006403;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleocytoplasmic transport#GO:0006913;localization#GO:0051179;nucleic acid transport#GO:0050657;nuclear transport#GO:0051169;nuclear export#GO:0051168 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC121835747|UniProtKB=A0ACM8FVM1 A0ACM8FVM1 LOC121835747 PTHR33064:SF47 POL PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833282|UniProtKB=A0ACM8FL33 A0ACM8FL33 LOC121833282 PTHR10429:SF0 DNA-3-METHYLADENINE GLYCOSYLASE DNA-3-METHYLADENINE GLYCOSYLASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;DNA N-glycosylase activity#GO:0019104;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097 macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;response to stress#GO:0006950 DNA glycosylase#PC00010;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115331421|UniProtKB=A0ACM8FWB4 A0ACM8FWB4 LOC121835637 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8037606|UniProtKB=A0ACM8EBT4 A0ACM8EBT4 LOC8037606 PTHR16071:SF2 CHROMOSOME 1 OPEN READING FRAME 112 FIGNL1-INTERACTING REGULATOR OF RECOMBINATION AND MITOSIS IXOSC|EnsemblGenome=LOC8040379|UniProtKB=A0ACM8EPU4 A0ACM8EPU4 LOC8040379 PTHR45739:SF17 MATRIX PROTEIN, PUTATIVE-RELATED CHONDROITIN SULFATE PROTEOGLYCAN 4-LIKE cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;multicellular organismal-level homeostasis#GO:0048871;tissue homeostasis#GO:0001894;cellular process#GO:0009987;anatomical structure homeostasis#GO:0060249;multicellular organismal process#GO:0032501;homeostatic process#GO:0042592;epithelial structure maintenance#GO:0010669 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120849288|UniProtKB=A0ACM8F7K2 A0ACM8F7K2 LOC120849288 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8028157|UniProtKB=A0ACM8F2D7 A0ACM8F2D7 LOC8028157 PTHR10082:SF60 INTEGRIN BETA SUBUNIT INTEGRIN BETA-PS protein-containing complex binding#GO:0044877;integrin binding#GO:0005178;protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488;signaling receptor binding#GO:0005102 cell surface receptor signaling pathway#GO:0007166;cell adhesion mediated by integrin#GO:0033627;cell-cell adhesion#GO:0098609;cellular process#GO:0009987;signal transduction#GO:0007165;cell migration#GO:0016477;biological regulation#GO:0065007;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589;cell communication#GO:0007154;integrin-mediated signaling pathway#GO:0007229;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;cell motility#GO:0048870;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052 anchoring junction#GO:0070161;cell junction#GO:0030054;integrin complex#GO:0008305;signaling receptor complex#GO:0043235;plasma membrane#GO:0005886;cell-substrate junction#GO:0030055;focal adhesion#GO:0005925;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;protein complex involved in cell adhesion#GO:0098636;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020 integrin#PC00126 Integrin signalling pathway#P00034>Integrin beta#P00931 IXOSC|EnsemblGenome=LOC8024937|UniProtKB=A0ACM8DNP5 A0ACM8DNP5 LOC8024937 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8037970|UniProtKB=A0ACM8G0C0 A0ACM8G0C0 Ars2 PTHR13165:SF0 ARSENITE-RESISTANCE PROTEIN 2 SERRATE RNA EFFECTOR MOLECULE HOMOLOG molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of biosynthetic process#GO:0009889;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;primary miRNA processing#GO:0031053;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA metabolic process#GO:0016070;miRNA processing#GO:0035196;nucleic acid biosynthetic process#GO:0141187;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;nuclear body#GO:0016604;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120840675|UniProtKB=A0ACM8EP68 A0ACM8EP68 LOC120840675 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8053770|UniProtKB=A0ACM8G0N1 A0ACM8G0N1 LOC8053770 PTHR47970:SF41 KINESIN-LIKE PROTEIN KIF11 KINESIN FAMILY MEMBER 11 cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;plus-end-directed microtubule motor activity#GO:0008574;microtubule motor activity#GO:0003777;polypeptide conformation or assembly isomerase activity#GO:0120544;ATP-dependent activity#GO:0140657 mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;nuclear chromosome segregation#GO:0098813;sister chromatid segregation#GO:0000819;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;membraneless organelle assembly#GO:0140694;cell cycle#GO:0007049;microtubule cytoskeleton organization#GO:0000226;organelle fission#GO:0048285;nuclear division#GO:0000280;organelle assembly#GO:0070925;spindle elongation#GO:0051231;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;mitotic spindle assembly#GO:0090307;spindle assembly#GO:0051225;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitotic spindle#GO:0072686;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoskeleton#GO:0005856;spindle#GO:0005819 microtubule binding motor protein#PC00156 IXOSC|EnsemblGenome=LOC115325013|UniProtKB=A0ACM8FJ50 A0ACM8FJ50 LOC115325013 PTHR10005:SF26 SKI ONCOGENE-RELATED CORL nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;protein binding#GO:0005515;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of macromolecule metabolic process#GO:0010605;regulation of BMP signaling pathway#GO:0030510;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;negative regulation of BMP signaling pathway#GO:0030514;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of signal transduction#GO:0009968;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115314697|UniProtKB=A0ACM8EFC8 A0ACM8EFC8 LOC115314697 PTHR22734:SF2 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 U3 SMALL NUCLEOLAR RIBONUCLEOPROTEIN PROTEIN IMP4 nucleic acid binding#GO:0003676;binding#GO:0005488;snoRNA binding#GO:0030515;rRNA binding#GO:0019843;RNA binding#GO:0003723 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;preribosome#GO:0030684;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;small-subunit processome#GO:0032040;90S preribosome#GO:0030686;organelle lumen#GO:0043233;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120837219|UniProtKB=A0ACM8EHV4 A0ACM8EHV4 LOC120837219 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120838065|UniProtKB=A0ACM8EIH1 A0ACM8EIH1 LOC120838065 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121835206|UniProtKB=A0ACM8FTC7 A0ACM8FTC7 LOC121835206 PTHR46012:SF2 IP22168P UDP-D-XYLOSE:BETA-D-GLUCOSIDE ALPHA-1,3-D-XYLOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;pentosyltransferase activity#GO:0016763;UDP-xylosyltransferase activity#GO:0035252;glycosyltransferase activity#GO:0016757;xylosyltransferase activity#GO:0042285;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 IXOSC|EnsemblGenome=LOC115323232|UniProtKB=A0ACM8E2V5 A0ACM8E2V5 LOC115323232 PTHR46263:SF1 ARMADILLO REPEAT-CONTAINING PROTEIN 7 ARMADILLO REPEAT-CONTAINING PROTEIN 7 IXOSC|EnsemblGenome=LOC8035870|UniProtKB=A0ACM8EDU5 A0ACM8EDU5 alpha-Man-IIb PTHR11607:SF70 ALPHA-MANNOSIDASE ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8029953|UniProtKB=A0ACM8DTF6 A0ACM8DTF6 PTHR45891:SF3 ZINC FINGER HOMEOBOX PROTEIN ZINC FINGER PROTEIN 2 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120836064|UniProtKB=A0ACM8EQ15 A0ACM8EQ15 LOC120836064 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846654|UniProtKB=A0ACM8F2V7 A0ACM8F2V7 LOC120846654 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 ubiquitin-like protein transferase activity#GO:0019787;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096 cellular process#GO:0009987;protein modification by small protein conjugation#GO:0032446;primary metabolic process#GO:0044238;protein modification process#GO:0036211;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115330580|UniProtKB=A0ACM8F9U4 A0ACM8F9U4 LOC115330580 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029388|UniProtKB=A0ACM8DXK5 A0ACM8DXK5 LOC8029388 PTHR24300:SF403 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 306A1 steroid hydroxylase activity#GO:0008395;binding#GO:0005488;tetrapyrrole binding#GO:0046906;catalytic activity#GO:0003824;monooxygenase activity#GO:0004497;heme binding#GO:0020037;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887;response to xenobiotic stimulus#GO:0009410;lipid metabolic process#GO:0006629;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stimulus#GO:0050896;response to chemical#GO:0042221;cellular response to xenobiotic stimulus#GO:0071466;xenobiotic metabolic process#GO:0006805;steroid metabolic process#GO:0008202 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120843529|UniProtKB=A0ACM8EWB7 A0ACM8EWB7 LOC120843529 PTHR23080:SF143 THAP DOMAIN PROTEIN TRANSPOSASE HELIX-TURN-HELIX DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121832956|UniProtKB=A0ACM8G229 A0ACM8G229 LOC8029167 PTHR10285:SF70 URIDINE KINASE URIDINE-CYTIDINE KINASE transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;nucleoside kinase activity#GO:0019206 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 nucleotide kinase#PC00172;kinase#PC00137 Salvage pyrimidine ribonucleotides#P02775>Uridine kinase#P03150;Salvage pyrimidine ribonucleotides#P02775>CDP kinase#P03156;Salvage pyrimidine ribonucleotides#P02775>Cytidine kinase#P03149 IXOSC|EnsemblGenome=LOC8052806|UniProtKB=A0ACM8DVN5 A0ACM8DVN5 Es2 PTHR12940:SF0 ES-2 PROTEIN - RELATED SPLICING FACTOR ESS-2 HOMOLOG nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115324085|UniProtKB=A0ACM8F297 A0ACM8F297 LOC115324085 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC121048362|UniProtKB=A0ACM8FI88 A0ACM8FI88 LOC121048362 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8034970|UniProtKB=A0ACM8EDC4 A0ACM8EDC4 DNApol-alpha50 PTHR10536:SF0 DNA PRIMASE SMALL SUBUNIT DNA PRIMASE SMALL SUBUNIT catalytic activity, acting on RNA#GO:0140098;transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 RNA biosynthetic process#GO:0032774;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA metabolic process#GO:0016070;DNA-templated DNA replication#GO:0006261;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;nucleoplasm#GO:0005654;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nuclear DNA-directed RNA polymerase complex#GO:0055029;replisome#GO:0030894;replication fork#GO:0005657;chromosome#GO:0005694;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575 primase#PC00189 DNA replication#P00017>Primase#P00528 IXOSC|EnsemblGenome=LOC8043301|UniProtKB=A0ACM8EI66 A0ACM8EI66 LOC8043301 PTHR45973:SF35 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED LEUCINE-RICH REPEAT-CONTAINING PROTEIN 43 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC120842918|UniProtKB=A0ACM8EUU7 A0ACM8EUU7 LOC120842918 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836687|UniProtKB=A0ACM8G0K2 A0ACM8G0K2 LOC121836687 PTHR46481:SF23 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4-LIKE IXOSC|EnsemblGenome=LOC8053574|UniProtKB=A0ACM8DSW0 A0ACM8DSW0 LOC8053574 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8027306|UniProtKB=A0ACM8DZZ5 A0ACM8DZZ5 Ssb-c31a PTHR13215:SF0 RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120846165|UniProtKB=A0ACM8G5N5 A0ACM8G5N5 LOC120846165 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8032833|UniProtKB=A0ACM8DH03 A0ACM8DH03 LOC8032833 PTHR10984:SF36 ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN 1 localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;Golgi vesicle transport#GO:0048193;cellular process#GO:0009987;transport#GO:0006810 cytoplasm#GO:0005737;endomembrane system#GO:0012505;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 IXOSC|EnsemblGenome=LOC8031350|UniProtKB=A0ACM8EK05 A0ACM8EK05 LOC8031350 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320274|UniProtKB=A0ACM8E010 A0ACM8E010 LOC115320274 PTHR22624:SF49 CYSTEINE PROTEASE ATG4 CYSTEINE PROTEASE hydrolase activity#GO:0016787;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;protein-phosphatidylethanolamide deconjugating activity#GO:0019786;catalytic activity, acting on a protein#GO:0140096 cellular component organization#GO:0016043;primary metabolic process#GO:0044238;catabolic process#GO:0009056;piecemeal microautophagy of the nucleus#GO:0034727;proteolysis#GO:0006508;organelle assembly#GO:0070925;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;protein processing#GO:0016485;autophagosome organization#GO:1905037;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;autophagy#GO:0006914;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;macroautophagy#GO:0016236;biosynthetic process#GO:0009058;autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC8029680|UniProtKB=A0ACM8F252 A0ACM8F252 LOC8029680 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040;chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 glycosidase#PC00110;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034503|UniProtKB=A0ACM8DSK8 A0ACM8DSK8 RhoGDI PTHR10980:SF3 RHO GDP-DISSOCIATION INHIBITOR RHO GDP-DISSOCIATION INHIBITOR 3 enzyme regulator activity#GO:0030234;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772 intracellular signal transduction#GO:0035556;Rho protein signal transduction#GO:0007266;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;intracellular signaling cassette#GO:0141124;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 membrane#GO:0016020;cytosol#GO:0005829;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein-binding activity modulator#PC00095;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC115319527|UniProtKB=A0ACM8F6S6 A0ACM8F6S6 LOC115319527 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115325080|UniProtKB=A0ACM8EY65 A0ACM8EY65 LOC115325080 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8030308|UniProtKB=A0ACM8DGN2 A0ACM8DGN2 LOC8030308 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120843165|UniProtKB=A0ACM8EWH9 A0ACM8EWH9 LOC120843165 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836113|UniProtKB=A0ACM8EZ62 A0ACM8EZ62 LOC120836113 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121833005|UniProtKB=A0ACM8FHQ7 A0ACM8FHQ7 LOC121833005 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8052242|UniProtKB=A0ACM8EAN4 A0ACM8EAN4 Ctf4 PTHR19932:SF10 WD REPEAT AND HMG-BOX DNA BINDING PROTEIN WD REPEAT AND HMG-BOX DNA-BINDING PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;mitotic cell cycle#GO:0000278;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;cell cycle#GO:0007049;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950 intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8041916|UniProtKB=A0ACM8DKR4 A0ACM8DKR4 LOC8041916 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8031132|UniProtKB=A0ACM8E095 A0ACM8E095 LOC8031132 PTHR12112:SF22 BNIP - RELATED MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE-RELATED cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 phosphodiesterase#PC00185;metabolite interconversion enzyme#PC00262;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8030477|UniProtKB=A0ACM8E0Y4 A0ACM8E0Y4 Glg1 PTHR11884:SF2 SELECTIN LIGAND RELATED GOLGI COMPLEX-LOCALIZED GLYCOPROTEIN 1, ISOFORM B intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115324476|UniProtKB=A0ACM8EPR3 A0ACM8EPR3 LOC115324476 PTHR10900:SF126 PERIOSTIN-RELATED MUCIN-5AC-RELATED protein binding#GO:0005515;binding#GO:0005488;cell adhesion molecule binding#GO:0050839 extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;cellular component organization#GO:0016043;cell-cell adhesion#GO:0098609;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120836103|UniProtKB=A0ACM8EQV9 A0ACM8EQV9 LOC120836103 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115321031|UniProtKB=A0ACM8EZI8 A0ACM8EZI8 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121046018|UniProtKB=A0ACM8FRI9 A0ACM8FRI9 mRpS2 PTHR12534:SF0 30S RIBOSOMAL PROTEIN S2 PROKARYOTIC AND ORGANELLAR SMALL RIBOSOMAL SUBUNIT PROTEIN US2M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;membrane-enclosed lumen#GO:0031974;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121833443|UniProtKB=A0ACM8FL21 A0ACM8FL21 LOC121833443 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028843|UniProtKB=A0ACM8DY83 A0ACM8DY83 LOC8028843 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8026772|UniProtKB=A0ACM8FU23 A0ACM8FU23 ft PTHR24028:SF342 CADHERIN-87A PROTOCADHERIN FAT 4 cellular process#GO:0009987;cell adhesion#GO:0007155 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cadherin#PC00057;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8053038|UniProtKB=A0ACM8DPX8 A0ACM8DPX8 LOC8053038 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8040960|UniProtKB=A0ACM8G0T7 A0ACM8G0T7 LOC8040960 PTHR12253:SF42 RH14732P PHOSPHOLIPASE A2 A2-type glycerophospholipase activity#GO:0004623;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;lipase activity#GO:0016298 IXOSC|EnsemblGenome=LOC8031210|UniProtKB=A0ACM8FDJ3 A0ACM8FDJ3 LOC8031210 PTHR10231:SF36 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-N-ACETYLGLUCOSAMINE TRANSPORTER UDP-galactose transmembrane transporter activity#GO:0005459;organophosphate ester transmembrane transporter activity#GO:0015605;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;nucleotide-sugar transmembrane transporter activity#GO:0005338;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 transporter#PC00227 IXOSC|EnsemblGenome=LOC120836688|UniProtKB=A0ACM8G7I7 A0ACM8G7I7 LOC120836688 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8041131|UniProtKB=A0ACM8EB82 A0ACM8EB82 LOC8041131 PTHR11950:SF31 RUNT RELATED PROTEIN LOZENGE sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA-binding transcription factor#PC00218;Runt transcription factor#PC00254 IXOSC|EnsemblGenome=LOC121834755|UniProtKB=A0ACM8FQY0 A0ACM8FQY0 LOC121834755 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836281|UniProtKB=A0ACM8FXN1 A0ACM8FXN1 LOC121836281 PTHR10484:SF162 HISTONE H4 HISTONE H4-LIKE PROTEIN TYPE G structural molecule activity#GO:0005198 cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;cellular component assembly#GO:0022607;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;protein-DNA complex assembly#GO:0065004;nucleosome organization#GO:0034728;cellular component organization or biogenesis#GO:0071840;protein-DNA complex organization#GO:0071824;protein-containing complex organization#GO:0043933 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115328825|UniProtKB=A0ACM8EXH7 A0ACM8EXH7 LOC115328825 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8026807|UniProtKB=A0ACM8DYJ3 A0ACM8DYJ3 Pp2A-29B PTHR10648:SF38 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED structural molecule activity#GO:0005198;protein complex scaffold activity#GO:0140378 microtubule cytoskeleton organization#GO:0000226;sister chromatid cohesion#GO:0007062;organelle assembly#GO:0070925;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;meiotic sister chromatid cohesion#GO:0051177;chromosome organization#GO:0051276;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;chromosome segregation#GO:0007059;cytoskeleton organization#GO:0007010;cellular component assembly#GO:0022607;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;spindle assembly#GO:0051225 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;cytosol#GO:0005829;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;intracellular organelle#GO:0043229 phosphatase modulator#PC00184 FGF signaling pathway#P00021>PP2A#P00629 IXOSC|EnsemblGenome=LOC120842440|UniProtKB=A0ACM8EUX4 A0ACM8EUX4 LOC120842440 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115311903|UniProtKB=A0ACM8EKF1 A0ACM8EKF1 LOC115311903 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8032375|UniProtKB=A0ACM8DYL7 A0ACM8DYL7 LOC8032375 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;telomere organization#GO:0032200;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 IXOSC|EnsemblGenome=LOC8025548|UniProtKB=A0ACM8DWV7 A0ACM8DWV7 conu PTHR14963:SF1 RHO GTPASE ACTIVATING PROTEIN 18,19-RELATED RHO GTPASE-ACTIVATING PROTEIN CONUNDRUM enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047 regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;regulation of actin polymerization or depolymerization#GO:0008064;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of actin filament polymerization#GO:0030833;regulation of response to stimulus#GO:0048583;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;regulation of small GTPase mediated signal transduction#GO:0051056;cellular component organization or biogenesis#GO:0071840;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;regulation of cellular component size#GO:0032535;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of protein polymerization#GO:0032271;regulation of signaling#GO:0023051;regulation of actin filament length#GO:0030832;regulation of intracellular signal transduction#GO:1902531;regulation of biological quality#GO:0065008 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC120845276|UniProtKB=A0ACM8F1E4 A0ACM8F1E4 LOC120845276 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042776|UniProtKB=A0ACM8F906 A0ACM8F906 eIF2A PTHR13227:SF0 EUKARYOTIC TRANSLATION INITIATION FACTOR 2A EUKARYOTIC TRANSLATION INITIATION FACTOR 2A translation initiation factor activity#GO:0003743;translation factor activity#GO:0180051 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;translation#GO:0006412;translational initiation#GO:0006413;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 Gonadotropin-releasing hormone receptor pathway#P06664>EIF2A#P06762 IXOSC|EnsemblGenome=LOC115325764|UniProtKB=A0ACM8FYF8 A0ACM8FYF8 LOC115325764 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850235|UniProtKB=A0ACM8F9R8 A0ACM8F9R8 LOC121835759 PTHR23098:SF25 AGAP001331-PA-RELATED REGULATORY PROTEIN ZESTE IXOSC|EnsemblGenome=LOC8053518|UniProtKB=A0ACM8F675 A0ACM8F675 LOC8053518 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC121836367|UniProtKB=A0ACM8FZG0 A0ACM8FZG0 LOC121836367 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 methyltransferase#PC00155;transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8042973|UniProtKB=A0ACM8E8M1 A0ACM8E8M1 LOC8042973 PTHR12274:SF3 GRANULIN GRANULIN PRECURSOR extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8033033|UniProtKB=A0ACM8FLS6 A0ACM8FLS6 LOC8033033 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120842582|UniProtKB=A0ACM8EV78 A0ACM8EV78 LOC120842582 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121838417|UniProtKB=A0ACM8G905 A0ACM8G905 LOC121838417 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8042027|UniProtKB=A0ACM8DKS3 A0ACM8DKS3 LOC8042027 PTHR14215:SF0 PROTEIN OF UNKNOWN FUNCTION DUF729 MITOCHONDRIAL FISSION REGULATOR 2 mitochondrion organization#GO:0007005;mitochondrial fission#GO:0000266;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;aerobic respiration#GO:0009060;cellular component organization or biogenesis#GO:0071840;organelle fission#GO:0048285;energy derivation by oxidation of organic compounds#GO:0015980;cellular respiration#GO:0045333;generation of precursor metabolites and energy#GO:0006091;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC120837550|UniProtKB=A0ACM8EHR5 A0ACM8EHR5 PTHR11802:SF472 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CPVL-RELATED peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine-type peptidase activity#GO:0008236 serine protease#PC00203 IXOSC|EnsemblGenome=LOC121046941|UniProtKB=A0ACM8FDX3 A0ACM8FDX3 LOC121046941 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120846858|UniProtKB=A0ACM8F492 A0ACM8F492 LOC120846858 PTHR11669:SF20 REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT REPLICATION FACTOR C SUBUNIT 4 ATP-dependent activity, acting on DNA#GO:0008094;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity#GO:0140657 response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;DNA-templated DNA replication#GO:0006261;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;cellular response to stress#GO:0033554 replication fork#GO:0005657;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 DNA-directed DNA polymerase#PC00018 DNA replication#P00017>RFC#P00529 IXOSC|EnsemblGenome=LOC8050562|UniProtKB=A0ACM8DLF4 A0ACM8DLF4 LOC8050562 PTHR11610:SF199 LIPASE PANCREATIC TRIACYLGLYCEROL LIPASE-LIKE ISOFORM X2 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8034640|UniProtKB=A0ACM8FSQ1 A0ACM8FSQ1 LOC8034640 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 cellular process#GO:0009987;metabolic process#GO:0008152;catabolic process#GO:0009056 extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC120848625|UniProtKB=A0ACM8F6E8 A0ACM8F6E8 LOC120848625 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027251|UniProtKB=A0ACM8DIV8 A0ACM8DIV8 lic PTHR48013:SF11 DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED MITOGEN-ACTIVATED PROTEIN KINASE KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;phosphotransferase activity, alcohol group as acceptor#GO:0016773 biological regulation#GO:0065007;signaling#GO:0023052;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;cell communication#GO:0007154;MAPK cascade#GO:0000165 non-receptor serine/threonine protein kinase#PC00167 FGF signaling pathway#P00021>MKK3,6#P00625;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>MEK#P00891;EGF receptor signaling pathway#P00018>MKK3,6#P00540;Huntington disease#P00029>SEK-1#P00792 IXOSC|EnsemblGenome=LOC115310497|UniProtKB=A0ACM8DPU0 A0ACM8DPU0 Coprox PTHR10755:SF0 COPROPORPHYRINOGEN III OXIDASE, MITOCHONDRIAL OXYGEN-DEPENDENT COPROPORPHYRINOGEN-III OXIDASE, MITOCHONDRIAL catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627 pigment biosynthetic process#GO:0046148;porphyrin-containing compound metabolic process#GO:0006778;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152;porphyrin-containing compound biosynthetic process#GO:0006779;cellular process#GO:0009987;pigment metabolic process#GO:0042440;heme biosynthetic process#GO:0006783;biosynthetic process#GO:0009058;heme metabolic process#GO:0042168;tetrapyrrole biosynthetic process#GO:0033014 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262;oxidase#PC00175 Heme biosynthesis#P02746>Coproporphyrinogen Oxidase (oxygen dependent)#P02980 IXOSC|EnsemblGenome=LOC120843742|UniProtKB=A0ACM8EWK7 A0ACM8EWK7 LOC120843742 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320773|UniProtKB=A0ACM8EJ03 A0ACM8EJ03 LOC115320773 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cell communication#GO:0010646;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121835108|UniProtKB=A0ACM8FSG0 A0ACM8FSG0 LOC121835108 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332795|UniProtKB=A0ACM8EDN3 A0ACM8EDN3 LOC115332795 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8041175|UniProtKB=A0ACM8DPI6 A0ACM8DPI6 epsilonCOP PTHR10805:SF0 COATOMER SUBUNIT EPSILON COATOMER SUBUNIT EPSILON cellular process#GO:0009987;Golgi vesicle transport#GO:0048193;transport#GO:0006810;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 Golgi-associated vesicle membrane#GO:0030660;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;COPI vesicle coat#GO:0030126;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;cytoplasmic vesicle#GO:0031410;coated membrane#GO:0048475;membrane coat#GO:0030117;intracellular organelle#GO:0043229;vesicle coat#GO:0030120;cytoplasm#GO:0005737;COPI-coated vesicle#GO:0030137;protein-containing complex#GO:0032991;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;Golgi apparatus#GO:0005794;Golgi-associated vesicle#GO:0005798 vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC8052348|UniProtKB=A0ACM8DM32 A0ACM8DM32 LOC8052348 PTHR10334:SF498 CYSTEINE-RICH SECRETORY PROTEIN-RELATED LD39025P defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8042979|UniProtKB=A0ACM8ED89 A0ACM8ED89 PTHR10229:SF0 GTP-BINDING PROTEIN HFLX GTP-BINDING PROTEIN 6-RELATED binding#GO:0005488;ribosome binding#GO:0043022;protein-containing complex binding#GO:0044877;ribonucleoprotein complex binding#GO:0043021 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115325839|UniProtKB=A0ACM8E658 A0ACM8E658 LOC115325839 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;cellular process#GO:0009987;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;microbody#GO:0042579;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121833600|UniProtKB=A0ACM8FLT9 A0ACM8FLT9 LOC121833600 PTHR31635:SF196 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115313170|UniProtKB=A0ACM8EQT2 A0ACM8EQT2 LOC115313170 PTHR22930:SF269 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025810|UniProtKB=A0ACM8DQA8 A0ACM8DQA8 LOC8025810 PTHR10188:SF50 L-ASPARAGINASE N(4)-(BETA-N-ACETYLGLUCOSAMINYL)-L-ASPARAGINASE hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 lysosome#GO:0005764;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;intracellular organelle#GO:0043229;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8024122|UniProtKB=A0ACM8G5S2 A0ACM8G5S2 LOC8024122 PTHR24070:SF268 RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY RAS-RELATED PROTEIN M-RAS hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides#GO:0016817 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signaling#GO:0023052;biological regulation#GO:0065007;small GTPase-mediated signal transduction#GO:0007264;intracellular signaling cassette#GO:0141124;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;establishment or maintenance of cell polarity#GO:0007163;Ras protein signal transduction#GO:0007265;intracellular signal transduction#GO:0035556;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 small GTPase#PC00208 EGF receptor signaling pathway#P00018>Ras#P00552 IXOSC|EnsemblGenome=LOC115310195|UniProtKB=A0ACM8EL30 A0ACM8EL30 PTHR15999:SF2 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 ZINC FINGER CW-TYPE PWWP DOMAIN PROTEIN 1 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC115320703|UniProtKB=A0ACM8EQ03 A0ACM8EQ03 LOC8033499 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC115317129|UniProtKB=A0ACM8DWU4 A0ACM8DWU4 LOC115317129 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC121046865|UniProtKB=A0ACM8FF23 A0ACM8FF23 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836737|UniProtKB=A0ACM8G0A5 A0ACM8G0A5 LOC121836737 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8028626|UniProtKB=A0ACM8F7W8 A0ACM8F7W8 sdk PTHR13817:SF121 TITIN PROTEIN SIDEKICK HOMOLOG cell adhesion#GO:0007155;synapse organization#GO:0050808;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;anatomical structure development#GO:0048856;cell junction assembly#GO:0034329;cellular component organization#GO:0016043;synapse assembly#GO:0007416;cell junction organization#GO:0034330;developmental process#GO:0032502;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;homophilic cell-cell adhesion#GO:0007156;cellular component biogenesis#GO:0044085;cell-cell adhesion#GO:0098609;nervous system development#GO:0007399;cellular component assembly#GO:0022607;multicellular organismal process#GO:0032501 synapse#GO:0045202;cellular anatomical structure#GO:0110165;cell junction#GO:0030054 structural protein#PC00211 IXOSC|EnsemblGenome=LOC8051913|UniProtKB=A0ACM8DLW8 A0ACM8DLW8 LOC8051913 PTHR45995:SF1 FAMILY NOT NAMED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE NIMA-INTERACTING 4 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8028602|UniProtKB=A0ACM8E0L4 A0ACM8E0L4 LOC8028602 PTHR11441:SF0 THYMIDINE KINASE THYMIDINE KINASE, CYTOSOLIC transferase activity#GO:0016740;nucleobase-containing compound kinase activity#GO:0019205;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;deoxynucleoside kinase activity#GO:0019136 nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124;small molecule metabolic process#GO:0044281;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238 kinase#PC00137;nucleotide kinase#PC00172 Salvage pyrimidine deoxyribonucleotides#P02774>Deoxyuridine kinase#P03146;Salvage pyrimidine deoxyribonucleotides#P02774>Thymidine kinase#P03147 IXOSC|EnsemblGenome=LOC120846348|UniProtKB=A0ACM8F1W0 A0ACM8F1W0 LOC120846348 PTHR45918:SF1 ALPHA-1,3/1,6-MANNOSYLTRANSFERASE ALG2 ALPHA-1,3_1,6-MANNOSYLTRANSFERASE ALG2 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120835983|UniProtKB=A0ACM8ELL6 A0ACM8ELL6 LOC120835983 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC120851192|UniProtKB=A0ACM8FBJ0 A0ACM8FBJ0 LOC120851192 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121045765|UniProtKB=A0ACM8FAX5 A0ACM8FAX5 LOC121045765 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8034185|UniProtKB=A0ACM8EA62 A0ACM8EA62 LOC8034185 PTHR10706:SF130 F-BOX FAMILY PROTEIN F-BOX DOMAIN-CONTAINING PROTEIN protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8035951|UniProtKB=A0ACM8E085 A0ACM8E085 LOC8035951 PTHR24246:SF61 OLFACTORY RECEPTOR AND ADENOSINE RECEPTOR ADENOSINE RECEPTOR, ISOFORM A transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;G protein-coupled receptor signaling pathway#GO:0007186;cell surface receptor signaling pathway#GO:0007166;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled adenosine receptor signaling pathway#GO:0001973;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711 IXOSC|EnsemblGenome=LOC8031931|UniProtKB=A0ACM8E8G2 A0ACM8E8G2 PTHR24219:SF4 LIM DOMAIN-CONTAINING PROTEIN JUB LIM DOMAIN-CONTAINING PROTEIN JUB transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;transcription regulator activity#GO:0140110 negative regulation of metabolic process#GO:0009892;regulation of hippo signaling#GO:0035330;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;negative regulation of hippo signaling#GO:0035331;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;negative regulation of translation#GO:0017148;regulation of signaling#GO:0023051;negative regulation of signal transduction#GO:0009968;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of protein metabolic process#GO:0051248;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;post-transcriptional gene silencing#GO:0016441;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of response to stimulus#GO:0048583 nucleus#GO:0005634;cell-cell junction#GO:0005911;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;adherens junction#GO:0005912;membraneless organelle#GO:0043228;cell junction#GO:0030054;intracellular membrane-bounded organelle#GO:0043231;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;P-body#GO:0000932;anchoring junction#GO:0070161;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC8035707|UniProtKB=A0ACM8DU36 A0ACM8DU36 LOC8035707 PTHR10231:SF43 NUCLEOTIDE-SUGAR TRANSMEMBRANE TRANSPORTER UDP-GALACTOSE TRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 membrane#GO:0016020;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 transporter#PC00227 IXOSC|EnsemblGenome=LOC8037313|UniProtKB=A0ACM8EVH5 A0ACM8EVH5 LOC8037313 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121836809|UniProtKB=A0ACM8G078 A0ACM8G078 LOC121836809 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8043126|UniProtKB=A0ACM8DMS1 A0ACM8DMS1 LOC8043126 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;exopeptidase activity#GO:0008238;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8024837|UniProtKB=A0ACM8EBX1 A0ACM8EBX1 LOC8024837 PTHR11706:SF113 SOLUTE CARRIER PROTEIN FAMILY 11 MEMBER PROTEIN MALVOLIO transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;iron ion transmembrane transporter activity#GO:0005381 iron ion transport#GO:0006826;transition metal ion transport#GO:0000041;inorganic ion homeostasis#GO:0098771;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;monoatomic ion transport#GO:0006811;intracellular monoatomic ion homeostasis#GO:0006873;intracellular iron ion homeostasis#GO:0006879;metal ion transport#GO:0030001;homeostatic process#GO:0042592;iron ion transmembrane transport#GO:0034755;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;transport#GO:0006810;chemical homeostasis#GO:0048878;establishment of localization#GO:0051234;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;plasma membrane#GO:0005886;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;endosome membrane#GO:0010008;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8035093|UniProtKB=A0ACM8DQF3 A0ACM8DQF3 LOC8035093 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC120847166|UniProtKB=A0ACM8FPX9 A0ACM8FPX9 PTHR10574:SF449 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;multicellular organismal process#GO:0032501;tissue development#GO:0009888;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;cell morphogenesis involved in neuron differentiation#GO:0048667;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;basement membrane#GO:0005604;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 IXOSC|EnsemblGenome=LOC120838455|UniProtKB=A0ACM8EK17 A0ACM8EK17 PTHR48528:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841718|UniProtKB=A0ACM8ETB8 A0ACM8ETB8 LOC120841718 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8037067|UniProtKB=A0ACM8DN01 A0ACM8DN01 LOC8037067 PTHR11390:SF20 PROKARYOTIC DNA TOPOISOMERASE DNA TOPOISOMERASE 3-BETA-1 macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097 cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8040451|UniProtKB=A0ACM8FEC1 A0ACM8FEC1 LOC8040451 PTHR11610:SF200 LIPASE FI22312P1 catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid metabolic process#GO:0006629;cellular process#GO:0009987;lipid catabolic process#GO:0016042;primary metabolic process#GO:0044238;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115310909|UniProtKB=A0ACM8DQ48 A0ACM8DQ48 Nedd8 PTHR10666:SF173 UBIQUITIN UBIQUITIN-LIKE PROTEIN NEDD8 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of proteolysis#GO:0030162;biological regulation#GO:0065007;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;cellular process#GO:0009987;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;nucleus#GO:0005634;ribosome#GO:0005840 IXOSC|EnsemblGenome=LOC8043253|UniProtKB=A0ACM8DL38 A0ACM8DL38 ND-PDSW PTHR13094:SF1 NADH-UBIQUINONE OXIDOREDUCTASE PDSW SUBUNIT NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 10 respiratory chain complex#GO:0098803;membrane protein complex#GO:0098796;oxidoreductase complex#GO:1990204;membrane#GO:0016020;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;catalytic complex#GO:1902494;respiratory chain complex I#GO:0045271;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115327256|UniProtKB=A0ACM8F560 A0ACM8F560 LOC115327256 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC115330859|UniProtKB=A0ACM8FFN1 A0ACM8FFN1 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC120840795|UniProtKB=A0ACM8EQF8 A0ACM8EQF8 LOC120840795 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8032037|UniProtKB=A0ACM8DTD9 A0ACM8DTD9 LOC8032037 PTHR12422:SF1 GH09096P GH09096P IXOSC|EnsemblGenome=LOC115315805|UniProtKB=A0ACM8F8E0 A0ACM8F8E0 LOC115315805 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC121838450|UniProtKB=A0ACM8G8B8 A0ACM8G8B8 LOC121838450 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833855|UniProtKB=A0ACM8FM21 A0ACM8FM21 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844777|UniProtKB=A0ACM8F0N0 A0ACM8F0N0 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029845|UniProtKB=A0ACM8DMU9 A0ACM8DMU9 LOC8029845 PTHR21347:SF14 CLEFT LIP AND PALATE ASSOCIATED TRANSMEMBRANE PROTEIN-RELATED LIPID SCRAMBLASE CLPTM1-RELATED membrane#GO:0016020;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 IXOSC|EnsemblGenome=LOC120839804|UniProtKB=A0ACM8ENQ5 A0ACM8ENQ5 LOC120839804 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121834775|UniProtKB=A0ACM8FRG2 A0ACM8FRG2 LOC121834775 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8038222|UniProtKB=A0ACM8DGR1 A0ACM8DGR1 LOC8038222 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120841311|UniProtKB=A0ACM8ERE3 A0ACM8ERE3 LOC120841311 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8025527|UniProtKB=A0ACM8DYC6 A0ACM8DYC6 LOC8025527 PTHR10270:SF317 SOX TRANSCRIPTION FACTOR TRANSCRIPTION FACTOR SOX-15-RELATED transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120844164|UniProtKB=A0ACM8FP30 A0ACM8FP30 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8034306|UniProtKB=A0ACM8F374 A0ACM8F374 bsk PTHR24055:SF598 MITOGEN-ACTIVATED PROTEIN KINASE STRESS-ACTIVATED PROTEIN KINASE JNK protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 MAPK cascade#GO:0000165;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;JNK cascade#GO:0007254;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Interferon-gamma signaling pathway#P00035>Serine kinase#P00955;Apoptosis signaling pathway#P00006>JNK#P00274;Alzheimer disease-amyloid secretase pathway#P00003>MAPK#P00099;Oxidative stress response#P00046>JNK1/2#P01129;Toll receptor signaling pathway#P00054>JNK#P01375;Parkinson disease#P00049>SAPK#P01219;Angiogenesis#P00005>JNK1#P00221;Ras Pathway#P04393>JNK#P04572;TGF-beta signaling pathway#P00052>JNK#P01284;FGF signaling pathway#P00021>JNK1-3#P00628;Integrin signalling pathway#P00034>Jnk#P00951;FAS signaling pathway#P00020>JNK#P00615;EGF receptor signaling pathway#P00018>JNK1-3#P00545 IXOSC|EnsemblGenome=LOC8041832|UniProtKB=A0ACM8EPE5 A0ACM8EPE5 TSG101 PTHR23306:SF3 TUMOR SUSCEPTIBILITY GENE 101 PROTEIN-RELATED TUMOR SUPPRESSOR PROTEIN 101 protein binding#GO:0005515;ubiquitin binding#GO:0043130;binding#GO:0005488 establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179;transport#GO:0006810;cellular process#GO:0009987 vesicle#GO:0031982;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;ESCRT I complex#GO:0000813;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8027010|UniProtKB=A0ACM8FMX8 A0ACM8FMX8 PTHR11426:SF280 HISTONE H3 HISTONE H3 cellular component assembly#GO:0022607;chromosome localization#GO:0050000;mitotic sister chromatid segregation#GO:0000070;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933;mitotic cell cycle process#GO:1903047;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;mitotic cell cycle#GO:0000278;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;nuclear chromosome segregation#GO:0098813;cellular component organization#GO:0016043;cell cycle#GO:0007049;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;protein-containing complex assembly#GO:0065003;mitotic metaphase chromosome alignment#GO:0007080;organelle fission#GO:0048285;localization#GO:0051179;kinetochore organization#GO:0051383;organelle localization#GO:0051640;nuclear division#GO:0000280;organelle assembly#GO:0070925;kinetochore assembly#GO:0051382 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 IXOSC|EnsemblGenome=LOC115328431|UniProtKB=A0ACM8E9H9 A0ACM8E9H9 garz PTHR10663:SF412 GUANYL-NUCLEOTIDE EXCHANGE FACTOR GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1 transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;establishment of localization#GO:0051234;Golgi organization#GO:0007030;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;Golgi cisterna#GO:0031985;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi cis cisterna#GO:0000137;Golgi apparatus subcompartment#GO:0098791;Golgi stack#GO:0005795;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC8038398|UniProtKB=A0ACM8DN79 A0ACM8DN79 LOC8038398 PTHR15104:SF0 DIHYDROPTERIDINE REDUCTASE DIHYDROPTERIDINE REDUCTASE purine nucleotide binding#GO:0017076;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;binding#GO:0005488;anion binding#GO:0043168;small molecule binding#GO:0036094 biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8035458|UniProtKB=A0ACM8FQV1 A0ACM8FQV1 LOC8035458 PTHR12191:SF30 SOLUTE CARRIER FAMILY 39 ZINC TRANSPORTER FOI active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;zinc ion transmembrane transporter activity#GO:0005385;bicarbonate transmembrane transporter activity#GO:0015106;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;transition metal ion transmembrane transporter activity#GO:0046915 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;zinc ion transmembrane transport#GO:0071577;transition metal ion transport#GO:0000041;metal ion transport#GO:0030001;homeostatic process#GO:0042592;inorganic ion import across plasma membrane#GO:0099587;import across plasma membrane#GO:0098739;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;inorganic cation import across plasma membrane#GO:0098659;cellular homeostasis#GO:0019725;import into cell#GO:0098657;establishment of localization#GO:0051234;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;monoatomic cation transmembrane transport#GO:0098655;zinc ion transport#GO:0006829;monoatomic ion transmembrane transport#GO:0034220;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC120845320|UniProtKB=A0ACM8G564 A0ACM8G564 BORCS5 PTHR31634:SF2 BLOC-1-RELATED COMPLEX SUBUNIT 5 BLOC-1-RELATED COMPLEX SUBUNIT 5 regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;microtubule-based movement#GO:0007018;regulation of cellular process#GO:0050794;regulation of microtubule-based movement#GO:0060632;microtubule-based transport#GO:0099111;regulation of microtubule-based process#GO:0032886;organelle localization#GO:0051640;cellular localization#GO:0051641;localization#GO:0051179;lysosome localization#GO:0032418;cellular process#GO:0009987;positive regulation of transport#GO:0051050;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;establishment of localization in cell#GO:0051649;organelle transport along microtubule#GO:0072384;biological regulation#GO:0065007;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;regulation of transport#GO:0051049;regulation of localization#GO:0032879;transport along microtubule#GO:0010970;establishment of localization#GO:0051234 cytoplasm#GO:0005737;vacuole#GO:0005773;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;lysosomal membrane#GO:0005765;presynapse#GO:0098793;secretory vesicle#GO:0099503;bounding membrane of organelle#GO:0098588;lytic vacuole#GO:0000323;cell junction#GO:0030054;cytoplasmic side of membrane#GO:0098562;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;lysosome#GO:0005764;lytic vacuole membrane#GO:0098852;intracellular vesicle#GO:0097708;side of membrane#GO:0098552;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;transport vesicle membrane#GO:0030658;endomembrane system#GO:0012505;transport vesicle#GO:0030133;membrane#GO:0016020;vesicle membrane#GO:0012506;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;vacuolar membrane#GO:0005774;intracellular membrane-bounded organelle#GO:0043231;synaptic vesicle#GO:0008021;vesicle#GO:0031982;synaptic vesicle membrane#GO:0030672;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8043409|UniProtKB=A0ACM8DNX9 A0ACM8DNX9 LOC8043409 PTHR22692:SF33 MYOSIN VII, XV MYOSIN-VIIA actin binding motor protein#PC00040 IXOSC|EnsemblGenome=LOC8036863|UniProtKB=A0ACM8DK27 A0ACM8DK27 LOC8036863 PTHR12356:SF19 NUCLEAR MOVEMENT PROTEIN NUDC NUDC DOMAIN-CONTAINING PROTEIN 3 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein folding#GO:0006457;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8035706|UniProtKB=A0ACM8DGQ2 A0ACM8DGQ2 Dcps PTHR12978:SF0 HISTIDINE TRIAD HIT PROTEIN MEMBER M7GPPPX DIPHOSPHATASE nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;RNA decapping#GO:0110154;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115318079|UniProtKB=A0ACM8F4Q8 A0ACM8F4Q8 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026885|UniProtKB=A0ACM8FME3 A0ACM8FME3 PTHR10459:SF118 DNA LIGASE POLY [ADP-RIBOSE] POLYMERASE 2 catalytic activity#GO:0003824;transferase activity#GO:0016740;NAD+ poly-ADP-ribosyltransferase activity#GO:0003950;pentosyltransferase activity#GO:0016763;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757 response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302 membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;nucleus#GO:0005634 DNA metabolism protein#PC00009 FAS signaling pathway#P00020>PARP#P00600 IXOSC|EnsemblGenome=LOC8023680|UniProtKB=A0ACM8FRD0 A0ACM8FRD0 LOC8023680 PTHR15739:SF5 ZINC FINGER PROTEIN LD23158P IXOSC|EnsemblGenome=LOC8039972|UniProtKB=A0ACM8EUT9 A0ACM8EUT9 LOC8039972 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC115332834|UniProtKB=A0ACM8EDP6 A0ACM8EDP6 LOC115332834 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;catalytic activity#GO:0003824;transferase activity#GO:0016740 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8028156|UniProtKB=A0ACM8DZX3 A0ACM8DZX3 LOC8028156 PTHR24256:SF579 TRYPTASE-RELATED WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 1 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115317276|UniProtKB=A0ACM8F0J5 A0ACM8F0J5 LOC115317276 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8030544|UniProtKB=A0ACM8EPL8 A0ACM8EPL8 LOC8030544 PTHR24372:SF74 GLYCOPROTEIN HORMONE RECEPTOR LP13728P signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528 adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to hormone#GO:0009725;cellular process#GO:0009987;signal transduction#GO:0007165;response to chemical#GO:0042221;biological regulation#GO:0065007;cellular response to chemical stimulus#GO:0070887;G protein-coupled receptor signaling pathway#GO:0007186;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cellular response to hormone stimulus#GO:0032870;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8029628|UniProtKB=A0ACM8FNF5 A0ACM8FNF5 LOC8029628 PTHR21608:SF7 KINESIN-LIKE PROTEIN CG14535 KINESIN-LIKE PROTEIN CG14535 protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;binding#GO:0005488;microtubule binding#GO:0008017 regulation of locomotion#GO:0040012;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell motility#GO:2000145;regulation of cell migration#GO:0030334;regulation of biological process#GO:0050789;regulation of neuron migration#GO:2001222 IXOSC|EnsemblGenome=LOC120844849|UniProtKB=A0ACM8F0T9 A0ACM8F0T9 PTHR13144:SF0 TEX261 PROTEIN PROTEIN TEX261 cargo receptor activity#GO:0038024 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;localization#GO:0051179;cellular localization#GO:0051641;establishment of localization#GO:0051234;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC8025642|UniProtKB=A0ACM8DJF0 A0ACM8DJF0 LOC8025642 PTHR10270:SF324 SOX TRANSCRIPTION FACTOR SOXNEURO, ISOFORM B DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;brain development#GO:0007420;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;neurogenesis#GO:0022008;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;developmental process#GO:0032502;negative regulation of cellular process#GO:0048523;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;central nervous system development#GO:0007417;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;head development#GO:0060322;nervous system development#GO:0007399;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;multicellular organism development#GO:0007275;animal organ development#GO:0048513;neuron differentiation#GO:0030182;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218;HMG box transcription factor#PC00024 IXOSC|EnsemblGenome=LOC8051030|UniProtKB=A0ACM8EAC4 A0ACM8EAC4 cdm PTHR12363:SF33 TRANSPORTIN 3 AND IMPORTIN 13 IMPORTIN-13 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;protein localization to organelle#GO:0033365;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;protein localization to nucleus#GO:0034504;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC8051524|UniProtKB=A0ACM8E995 A0ACM8E995 LOC8051524 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8053243|UniProtKB=A0ACM8DGW6 A0ACM8DGW6 LOC8053243 PTHR24068:SF141 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2 N ubiquitin conjugating enzyme activity#GO:0061631;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;catalytic activity#GO:0003824;transferase activity#GO:0016740;ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787 response to stimulus#GO:0050896;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;post-translational protein modification#GO:0043687;cellular process#GO:0009987;response to stress#GO:0006950;protein K63-linked ubiquitination#GO:0070534;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA damage tolerance#GO:0006301;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Toll receptor signaling pathway#P00054>Ubc13#P01381 IXOSC|EnsemblGenome=LOC8023964|UniProtKB=A0ACM8DX73 A0ACM8DX73 PTHR19871:SF37 BETA TRANSDUCIN-RELATED PROTEIN GH25853P IXOSC|EnsemblGenome=LOC120837236|UniProtKB=A0ACM8EGV2 A0ACM8EGV2 LOC120837236 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120841373|UniProtKB=A0ACM8G2F8 A0ACM8G2F8 LOC120841373 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033750|UniProtKB=A0ACM8DIA2 A0ACM8DIA2 MED24 PTHR12898:SF1 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 24 transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription initiation#GO:2000142;regulation of biological process#GO:0050789;positive regulation of RNA metabolic process#GO:0051254;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;mediator complex#GO:0016592;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 general transcription factor#PC00259;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8050441|UniProtKB=A0ACM8DLE0 A0ACM8DLE0 LOC8050441 PTHR12901:SF10 SPERM PROTEIN HOMOLOG COENZYME Q-BINDING PROTEIN COQ10, MITOCHONDRIAL IXOSC|EnsemblGenome=LOC8024074|UniProtKB=A0ACM8DW07 A0ACM8DW07 LOC8024074 PTHR46491:SF10 CDGSH IRON SULFUR DOMAIN PROTEIN HOMOLOG IRON-BINDING ZINC FINGER CDGSH TYPE DOMAIN-CONTAINING PROTEIN iron-sulfur cluster binding#GO:0051536;small molecule binding#GO:0036094;binding#GO:0005488 metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8042205|UniProtKB=A0ACM8EQU9 A0ACM8EQU9 GAPcenA PTHR47219:SF9 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE GTPASE ACTIVATING PROTEIN AND CENTROSOME-ASSOCIATED, ISOFORM B binding#GO:0005488;enzyme binding#GO:0019899;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;protein binding#GO:0005515;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;molecular function regulator activity#GO:0098772 G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8030321|UniProtKB=A0ACM8DXL7 A0ACM8DXL7 LOC8030321 PTHR12107:SF0 VOLTAGE-DEPENDENT CALCIUM CHANNEL GAMMA SUBUNIT STARGAZIN-LIKE PROTEIN voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;transporter activity#GO:0005215;voltage-gated calcium channel activity#GO:0005245;channel regulator activity#GO:0016247;channel activity#GO:0015267;transporter regulator activity#GO:0141108;monoatomic cation channel activity#GO:0005261;molecular function regulator activity#GO:0098772;passive transmembrane transporter activity#GO:0022803;calcium channel activity#GO:0005262;transmembrane transporter activity#GO:0022857 positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;transmission of nerve impulse#GO:0019226;system process#GO:0003008;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;modulation of chemical synaptic transmission#GO:0050804;regulation of cell communication#GO:0010646;positive regulation of synaptic transmission#GO:0050806;localization within membrane#GO:0051668;regulation of signaling#GO:0023051;nervous system process#GO:0050877;localization#GO:0051179;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;positive regulation of signaling#GO:0023056;cellular localization#GO:0051641;regulation of biological quality#GO:0065008 membrane#GO:0016020;cell periphery#GO:0071944;neuron to neuron synapse#GO:0098984;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;postsynaptic specialization#GO:0099572;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;synaptic membrane#GO:0097060;signaling receptor complex#GO:0043235;transporter complex#GO:1990351;cell junction#GO:0030054;postsynapse#GO:0098794;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;synapse#GO:0045202;cellular anatomical structure#GO:0110165;organelle#GO:0043226;asymmetric synapse#GO:0032279;postsynaptic specialization membrane#GO:0099634;postsynaptic membrane#GO:0045211;postsynaptic density#GO:0014069;transmembrane transporter complex#GO:1902495;postsynaptic density membrane#GO:0098839 voltage-gated ion channel#PC00241;transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC115321687|UniProtKB=A0ACM8E1Y9 A0ACM8E1Y9 LOC115321687 PTHR14296:SF16 REMODELING AND SPACING FACTOR 1 REMODELING AND SPACING FACTOR 1 binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular component assembly#GO:0022607;regulation of nucleobase-containing compound metabolic process#GO:0019219 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;chromatin#GO:0000785;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ISWI-type complex#GO:0031010;ATPase complex#GO:1904949;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694 IXOSC|EnsemblGenome=LOC121835874|UniProtKB=A0ACM8FW62 A0ACM8FW62 LOC121835874 PTHR14903:SF6 SCLEROSTIN-RELATED CTCK DOMAIN-CONTAINING PROTEIN protein binding#GO:0005515;cytokine binding#GO:0019955;binding#GO:0005488 negative regulation of response to stimulus#GO:0048585;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of signal transduction#GO:0009968;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of BMP signaling pathway#GO:0030510;negative regulation of BMP signaling pathway#GO:0030514;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8041562|UniProtKB=A0ACM8E7N5 A0ACM8E7N5 LOC8041562 PTHR45873:SF1 DNA POLYMERASE ETA DNA POLYMERASE ETA DNA-directed DNA polymerase activity#GO:0003887;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 DNA synthesis involved in DNA replication#GO:0090592;nucleic acid biosynthetic process#GO:0141187;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to abiotic stimulus#GO:0009628;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA damage tolerance#GO:0006301;DNA damage response#GO:0006974;translesion synthesis#GO:0019985;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;response to stress#GO:0006950;macromolecule biosynthetic process#GO:0009059;response to radiation#GO:0009314;cellular process#GO:0009987;DNA biosynthetic process#GO:0071897 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;site of DNA damage#GO:0090734;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;replication fork#GO:0005657;nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120851027|UniProtKB=A0ACM8EA94 A0ACM8EA94 LOC8024846 PTHR24031:SF84 RNA HELICASE EUKARYOTIC INITIATION FACTOR 4A biosynthetic process#GO:0009058;protein biosynthetic process#GO:0160307;gene expression#GO:0010467;cytoplasmic translation#GO:0002181;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;translation#GO:0006412;translational initiation#GO:0006413;metabolic process#GO:0008152;cytoplasmic translational initiation#GO:0002183 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;intracellular protein-containing complex#GO:0140535;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8030627|UniProtKB=A0ACM8FEM4 A0ACM8FEM4 LOC8030627 PTHR16188:SF14 PROTEIN PHOSPHATASE 1 INHIBITOR POTENTIATED BY PROTEIN KINASE C GEO07393P1 phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;protein phosphatase inhibitor activity#GO:0004864;enzyme inhibitor activity#GO:0004857;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;protein phosphatase regulator activity#GO:0019888;protein serine/threonine phosphatase inhibitor activity#GO:0004865 phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC120848794|UniProtKB=A0ACM8F6R5 A0ACM8F6R5 LOC120848794 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040336|UniProtKB=A0ACM8DVH9 A0ACM8DVH9 Pat1 PTHR46575:SF1 AMYLOID PROTEIN-BINDING PROTEIN 2 AMYLOID PROTEIN-BINDING PROTEIN 2 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056 intracellular protein-containing complex#GO:0140535;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;Cul2-RING ubiquitin ligase complex#GO:0031462;transferase complex#GO:1990234;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC8037169|UniProtKB=A0ACM8DMZ6 A0ACM8DMZ6 LOC8037169 PTHR21068:SF55 SPARTIN SPARTIN negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of cell communication#GO:0010648;regulation of transmembrane receptor protein serine/threonine kinase signaling pathway#GO:0090092;negative regulation of biological process#GO:0048519;cell division#GO:0051301;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;negative regulation of BMP signaling pathway#GO:0030514;regulation of BMP signaling pathway#GO:0030510;cellular process#GO:0009987;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;regulation of cellular response to growth factor stimulus#GO:0090287;biological regulation#GO:0065007 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8041104|UniProtKB=A0ACM8FHU4 A0ACM8FHU4 LOC8041104 PTHR23235:SF207 KRUEPPEL-LIKE TRANSCRIPTION FACTOR SP1, ISOFORM F sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 C2H2 zinc finger transcription factor#PC00248 Huntington disease#P00029>Sp1#P00803 IXOSC|EnsemblGenome=LOC8041778|UniProtKB=A0ACM8EBF2 A0ACM8EBF2 LOC8041778 PTHR10276:SF3 CORE-BINDING FACTOR, BETA SUBUNIT CORE-BINDING FACTOR SUBUNIT BETA transcription coregulator activity#GO:0003712;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription regulator activity#GO:0140110;transcription coactivator activity#GO:0003713;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 nucleus#GO:0005634;RNA polymerase II transcription regulator complex#GO:0090575;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115324323|UniProtKB=A0ACM8FIM3 A0ACM8FIM3 LOC115324323 PTHR24346:SF36 MAP/MICROTUBULE AFFINITY-REGULATING KINASE SERINE_THREONINE-PROTEIN KINASE BRSK1 ISOFORM X1-RELATED protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8036507|UniProtKB=A0ACM8FD34 A0ACM8FD34 LOC8036507 PTHR47981:SF39 RAB FAMILY RAS-RELATED PROTEIN RAB-32 molecular function regulator activity#GO:0098772;ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818 lysosome organization#GO:0007040;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;transport#GO:0006810;lytic vacuole organization#GO:0080171;vacuolar transport#GO:0007034;phagocytosis#GO:0006909;intracellular transport#GO:0046907;phagolysosome assembly#GO:0001845;vesicle organization#GO:0016050;import into cell#GO:0098657;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;cellular component organization#GO:0016043;vesicle fusion#GO:0006906;endocytosis#GO:0006897;lysosomal transport#GO:0007041;organelle assembly#GO:0070925;endosome to lysosome transport#GO:0008333;vacuole organization#GO:0007033;cellular localization#GO:0051641;localization#GO:0051179 late endosome#GO:0005770;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;cytoplasm#GO:0005737;vacuole#GO:0005773;lytic vacuole#GO:0000323;intracellular vesicle#GO:0097708;lysosome#GO:0005764;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8043295|UniProtKB=A0ACM8DT35 A0ACM8DT35 LOC8043295 PTHR45902:SF7 LATROPHILIN RECEPTOR-LIKE PROTEIN A G-PROTEIN COUPLED RECEPTORS FAMILY 2 PROFILE 2 DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8050840|UniProtKB=A0ACM8ED21 A0ACM8ED21 LOC8050840 PTHR10183:SF439 CALPAIN CALPAIN CATALYTIC DOMAIN-CONTAINING PROTEIN catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115326203|UniProtKB=A0ACM8E5Q5 A0ACM8E5Q5 LOC115326203 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;deaminase activity#GO:0019239;catalytic activity#GO:0003824 negative regulation of protein metabolic process#GO:0051248;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of translation#GO:0006417;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;cellular process#GO:0009987;regulation of protein metabolic process#GO:0051246;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 mitochondrion#GO:0005739;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;deaminase#PC00088;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120836948|UniProtKB=A0ACM8EGT7 A0ACM8EGT7 LOC120836948 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120844566|UniProtKB=A0ACM8EZ38 A0ACM8EZ38 LOC120844566 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8027963|UniProtKB=A0ACM8EUH8 A0ACM8EUH8 LOC8027963 PTHR23157:SF24 GRIP AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 GOLGIN SUBFAMILY A MEMBER 1 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8051973|UniProtKB=A0ACM8FUV7 A0ACM8FUV7 CBP PTHR10827:SF106 RETICULOCALBIN CALCIUM-BINDING PROTEIN small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 calmodulin-related#PC00061;calcium-binding protein#PC00060 IXOSC|EnsemblGenome=LOC120842349|UniProtKB=A0ACM8ETM6 A0ACM8ETM6 LOC120842349 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC8029061|UniProtKB=A0ACM8DSY9 A0ACM8DSY9 LOC8029061 PTHR21274:SF0 MECKELIN MECKELIN plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031 cilium#GO:0005929;ciliary transition zone#GO:0035869;cell projection#GO:0042995;membrane-bounded organelle#GO:0043227;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8023239|UniProtKB=A0ACM8E627 A0ACM8E627 LOC8023239 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8023172|UniProtKB=A0ACM8E2Q6 A0ACM8E2Q6 LOC8023172 PTHR11177:SF409 CHITINASE CHITINASE 12-RELATED hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;chitin metabolic process#GO:0006030;chitin catabolic process#GO:0006032;aminoglycan catabolic process#GO:0006026;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8043898|UniProtKB=A0ACM8DMB0 A0ACM8DMB0 LOC8043898 PTHR10953:SF6 UBIQUITIN-ACTIVATING ENZYME E1 NEDD8-ACTIVATING ENZYME E1 CATALYTIC SUBUNIT ATP-dependent activity#GO:0140657;ligase activity, forming carbon-sulfur bonds#GO:0016877;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfurtransferase activity#GO:0016783;thiosulfate-cyanide sulfurtransferase activity#GO:0004792;transferase activity, transferring phosphorus-containing groups#GO:0016772;ubiquitin-like modifier activating enzyme activity#GO:0008641;ligase activity#GO:0016874;catalytic activity#GO:0003824;transferase activity#GO:0016740;nucleotidyltransferase activity#GO:0016779;catalytic activity, acting on a protein#GO:0140096 primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;post-translational protein modification#GO:0043687;metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 Ubiquitin proteasome pathway#P00060>E1#P01492 IXOSC|EnsemblGenome=LOC8039937|UniProtKB=A0ACM8DQ33 A0ACM8DQ33 LOC8039937 PTHR15092:SF37 POLY A -SPECIFIC RIBONUCLEASE/TARGET OF EGR1, MEMBER 1 TARGET OF EGR1 PROTEIN 1 nuclease activity#GO:0004518;snRNA binding#GO:0017069;hydrolase activity#GO:0016787;RNA binding#GO:0003723;3'-5'-RNA exonuclease activity#GO:0000175;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 RNA metabolic process#GO:0016070;snRNA metabolic process#GO:0016073;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;snRNA 3'-end processing#GO:0034472;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;snRNA processing#GO:0016180;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular membraneless organelle#GO:0043232;nuclear body#GO:0016604;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC115323229|UniProtKB=A0ACM8E3I4 A0ACM8E3I4 LOC115323229 PTHR10336:SF215 PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN PHOSPHOINOSITIDE PHOSPHOLIPASE C hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;glycerophospholipase activity#GO:0004620;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 lipase#PC00143;metabolite interconversion enzyme#PC00262;phospholipase#PC00186;hydrolase#PC00121 Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PLCbetagamma#P00874;Thyrotropin-releasing hormone receptor signaling pathway#P04394>PLC#P04581;5HT2 type receptor mediated signaling pathway#P04374>PLC#P04412;Histamine H1 receptor mediated signaling pathway#P04385>PLC#P04484;Oxytocin receptor mediated signaling pathway#P04391>PLC beta#P04530 IXOSC|EnsemblGenome=LOC120840606|UniProtKB=A0ACM8EQI9 A0ACM8EQI9 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8051334|UniProtKB=A0ACM8FE24 A0ACM8FE24 mRpS29 PTHR12810:SF0 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S29 SMALL RIBOSOMAL SUBUNIT PROTEIN MS29 structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198 mitochondrial matrix#GO:0005759;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC121834218|UniProtKB=A0ACM8FP88 A0ACM8FP88 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120843965|UniProtKB=A0ACM8EXB5 A0ACM8EXB5 LOC120843965 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120840265|UniProtKB=A0ACM8EP13 A0ACM8EP13 LOC120840265 PTHR46599:SF3 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120848626|UniProtKB=A0ACM8F5B7 A0ACM8F5B7 LOC120848626 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121834030|UniProtKB=A0ACM8FML8 A0ACM8FML8 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8051119|UniProtKB=A0ACM8EAN7 A0ACM8EAN7 LOC8051119 PTHR14191:SF3 PDZ DOMAIN CONTAINING PROTEIN GH04176P-RELATED protein-membrane adaptor activity#GO:0043495;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization within membrane#GO:0051668;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;cellular localization#GO:0051641;localization#GO:0051179;cellular process#GO:0009987;protein localization to plasma membrane#GO:0072659;macromolecule localization#GO:0033036;protein localization to membrane#GO:0072657 cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8053558|UniProtKB=A0ACM8FFW5 A0ACM8FFW5 LOC8053558 PTHR12169:SF6 ATPASE N2B AFG1-LIKE ATPASE ATP hydrolysis activity#GO:0016887;hydrolase activity#GO:0016787;ATP-dependent activity#GO:0140657;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC8030692|UniProtKB=A0ACM8EET0 A0ACM8EET0 mtRNApol PTHR10102:SF28 DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL DNA-DIRECTED RNA POLYMERASE, MITOCHONDRIAL transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;catalytic activity, acting on RNA#GO:0140098;sequence-specific DNA binding#GO:0043565;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 nucleobase-containing compound metabolic process#GO:0006139;mitochondrial transcription#GO:0006390;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mitochondrial gene expression#GO:0140053;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;nucleic acid biosynthetic process#GO:0141187 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transferase complex, transferring phosphorus-containing groups#GO:0061695;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;RNA polymerase complex#GO:0030880;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 DNA-directed RNA polymerase#PC00019 IXOSC|EnsemblGenome=LOC115332936|UniProtKB=A0ACM8EKW8 A0ACM8EKW8 LOC115332936 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115323767|UniProtKB=A0ACM8EG42 A0ACM8EG42 LOC115323767 PTHR22769:SF56 MUTT/NUDIX HYDROLASE 8-OXO-DGDP PHOSPHATASE NUDT18 hydrolase activity#GO:0016787;nucleoside diphosphate phosphatase activity#GO:0017110;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;hydrolase activity, acting on acid anhydrides#GO:0016817 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8042455|UniProtKB=A0ACM8DUV5 A0ACM8DUV5 LOC8042455 PTHR11085:SF6 NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED NAD-DEPENDENT PROTEIN DEACETYLASE SIRTUIN-2 deacylase activity#GO:0160215;transferase activity#GO:0016740;histone deacetylase activity#GO:0004407;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;NAD-dependent protein lysine deacetylase activity#GO:0034979;catalytic activity, acting on a protein#GO:0140096;acyltransferase activity#GO:0016746;histone modifying activity#GO:0140993;deacetylase activity#GO:0019213 regulation of gene expression#GO:0010468;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523;heterochromatin organization#GO:0070828;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;cellular component assembly#GO:0022607;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;nucleolus organization#GO:0007000;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115332587|UniProtKB=A0ACM8G920 A0ACM8G920 LOC115332587 PTHR45911:SF10 C2 DOMAIN-CONTAINING PROTEIN MULTIPLE C2 AND TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN ion binding#GO:0043167;small molecule binding#GO:0036094;binding#GO:0005488;calcium ion binding#GO:0005509;metal ion binding#GO:0046872;cation binding#GO:0043169 regulation of cellular process#GO:0050794;regulation of trans-synaptic signaling#GO:0099177;regulation of neurotransmitter secretion#GO:0046928;modulation of chemical synaptic transmission#GO:0050804;biological regulation#GO:0065007;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of secretion#GO:0051046;regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of secretion by cell#GO:1903530;regulation of neurotransmitter transport#GO:0051588;regulation of signaling#GO:0023051 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cell junction#GO:0030054;cytoplasm#GO:0005737;transport vesicle#GO:0030133;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;transport vesicle membrane#GO:0030658;presynapse#GO:0098793;vesicle membrane#GO:0012506;secretory vesicle#GO:0099503;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;exocytic vesicle#GO:0070382;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;synapse#GO:0045202;synaptic vesicle membrane#GO:0030672;vesicle#GO:0031982;synaptic vesicle#GO:0008021;intracellular vesicle#GO:0097708 IXOSC|EnsemblGenome=LOC120848541|UniProtKB=A0ACM8F6X4 A0ACM8F6X4 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120846748|UniProtKB=A0ACM8F360 A0ACM8F360 LOC120846748 PTHR11819:SF195 SOLUTE CARRIER FAMILY 5 SODIUM_GLUCOSE COTRANSPORTER transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120843814|UniProtKB=A0ACM8EX04 A0ACM8EX04 LOC120843814 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850654|UniProtKB=A0ACM8FBD1 A0ACM8FBD1 LOC120850654 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040386|UniProtKB=A0ACM8G7G1 A0ACM8G7G1 LOC8040386 PTHR46116:SF51 (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME (E3-INDEPENDENT) E2 UBIQUITIN-CONJUGATING ENZYME acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein conjugating enzyme activity#GO:0061650;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;aminoacyltransferase activity#GO:0016755 endosomal transport#GO:0016197;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;intracellular transport#GO:0046907;cytosolic transport#GO:0016482;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;retrograde transport, endosome to Golgi#GO:0042147 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8042519|UniProtKB=A0ACM8E5R7 A0ACM8E5R7 LOC8042519 PTHR10985:SF77 BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, HES-RELATED PROTEIN HAIRY cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of multicellular organismal development#GO:2000026;multicellular organism development#GO:0007275;anterior/posterior pattern specification#GO:0009952;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of multicellular organismal process#GO:0051239;negative regulation of macromolecule biosynthetic process#GO:0010558;anatomical structure development#GO:0048856;regulation of nervous system development#GO:0051960;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;pattern specification process#GO:0007389;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of developmental process#GO:0050793;regulation of neurogenesis#GO:0050767;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of cell differentiation#GO:0045595;regulation of nucleobase-containing compound metabolic process#GO:0019219;regionalization#GO:0003002;multicellular organismal process#GO:0032501;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of cell development#GO:0060284 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 Notch signaling pathway#P00045>E(spl)-C genes#G01541 IXOSC|EnsemblGenome=LOC115309937|UniProtKB=A0ACM8FSW2 A0ACM8FSW2 LOC115309937 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120842778|UniProtKB=A0ACM8EUL6 A0ACM8EUL6 LOC120842778 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8033287|UniProtKB=A0ACM8ERY1 A0ACM8ERY1 LOC8033287 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8038738|UniProtKB=A0ACM8F583 A0ACM8F583 LOC8038738 PTHR13356:SF0 OB FOLD NUCLEIC ACID BINDING PROTEIN-RELATED SOSS COMPLEX SUBUNIT B HOMOLOG DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;cellular response to stress#GO:0033554;response to stimulus#GO:0050896;regulation of cell cycle#GO:0051726;signaling#GO:0023052;negative regulation of cell cycle phase transition#GO:1901988;response to abiotic stimulus#GO:0009628;negative regulation of biological process#GO:0048519;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;regulation of biological process#GO:0050789;response to ionizing radiation#GO:0010212;negative regulation of cell cycle#GO:0045786;negative regulation of cell cycle G2/M phase transition#GO:1902750;double-strand break repair#GO:0006302;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA recombination#GO:0006310;negative regulation of G2/M transition of mitotic cell cycle#GO:0010972;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of cell cycle process#GO:0010564;response to stress#GO:0006950;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of G2/M transition of mitotic cell cycle#GO:0010389;intracellular signal transduction#GO:0035556;recombinational repair#GO:0000725;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cellular response to stimulus#GO:0051716;macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;negative regulation of cellular process#GO:0048523;DNA repair#GO:0006281;negative regulation of cell cycle process#GO:0010948;DNA damage response#GO:0006974;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of cell cycle G2/M phase transition#GO:1902749;regulation of mitotic cell cycle#GO:0007346;response to radiation#GO:0009314;mitotic G2/M transition checkpoint#GO:0044818 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 damaged DNA-binding protein#PC00086;DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115309817|UniProtKB=A0ACM8FZV7 A0ACM8FZV7 LOC115309817 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051968|UniProtKB=A0ACM8DLJ5 A0ACM8DLJ5 LOC8051968 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 cellular process#GO:0009987;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 transferase#PC00220 IXOSC|EnsemblGenome=LOC8054025|UniProtKB=A0ACM8E884 A0ACM8E884 LOC8054025 PTHR43380:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 catalytic complex#GO:1902494;transferase complex#GO:1990234;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991 dehydrogenase#PC00092;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8035923|UniProtKB=A0ACM8E603 A0ACM8E603 LOC8035923 PTHR10614:SF13 INSULIN RECEPTOR SUBSTRATE INSULIN RECEPTOR SUBSTRATE 1 protein binding#GO:0005515;signaling adaptor activity#GO:0035591;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068;enzyme binding#GO:0019899;protein-macromolecule adaptor activity#GO:0030674;signaling receptor binding#GO:0005102;kinase binding#GO:0019900;protein tyrosine kinase binding#GO:1990782;binding#GO:0005488;receptor tyrosine kinase binding#GO:0030971;molecular adaptor activity#GO:0060090;signaling receptor complex adaptor activity#GO:0030159 response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;response to peptide hormone#GO:0043434;intracellular signaling cassette#GO:0141124;response to hormone#GO:0009725;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to insulin stimulus#GO:0032869;cell surface receptor signaling pathway#GO:0007166;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;insulin-like growth factor receptor signaling pathway#GO:0048009;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;signaling#GO:0023052;cellular response to peptide hormone stimulus#GO:0071375;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to insulin#GO:0032868;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;response to nitrogen compound#GO:1901698;intracellular signal transduction#GO:0035556;cellular response to chemical stimulus#GO:0070887;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;insulin receptor signaling pathway#GO:0008286;response to oxygen-containing compound#GO:1901700 membrane#GO:0016020;cytosol#GO:0005829;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 PI3 kinase pathway#P00048>IRS#P01193;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>IRS 1-4#P00899;Insulin/IGF pathway-mitogen activated protein kinase kinase/MAP kinase cascade#P00032>IRS 1-4#P00887 IXOSC|EnsemblGenome=LOC8035674|UniProtKB=A0ACM8DZQ1 A0ACM8DZQ1 LOC8035674 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115320245|UniProtKB=A0ACM8G3I0 A0ACM8G3I0 LOC115320245 PTHR10434:SF11 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;transferase activity#GO:0016740 phospholipid metabolic process#GO:0006644;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654;lipid biosynthetic process#GO:0008610;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8038026|UniProtKB=A0ACM8FB61 A0ACM8FB61 LOC8038026 PTHR45627:SF16 ADENYLATE CYCLASE TYPE 1 ADENYLATE CYCLASE phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;adenylate cyclase activity#GO:0004016;lyase activity#GO:0016829 cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;cyclic nucleotide metabolic process#GO:0009187;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;nucleoside phosphate biosynthetic process#GO:1901293;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;phosphorus metabolic process#GO:0006793;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;cyclic nucleotide biosynthetic process#GO:0009190;purine-containing compound biosynthetic process#GO:0072522;G protein-coupled receptor signaling pathway#GO:0007186;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;signal transduction#GO:0007165;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;ribose phosphate biosynthetic process#GO:0046390;cyclic purine nucleotide metabolic process#GO:0052652;metabolic process#GO:0008152;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound biosynthetic process#GO:0034654;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 adenylate cyclase#PC00043 IXOSC|EnsemblGenome=LOC120848892|UniProtKB=A0ACM8F6L6 A0ACM8F6L6 LOC120848892 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8029885|UniProtKB=A0ACM8FEQ5 A0ACM8FEQ5 LOC8029885 PTHR46345:SF12 INVERTED FORMIN-2 FORMIN 3, ISOFORM B IXOSC|EnsemblGenome=LOC115318875|UniProtKB=A0ACM8FW06 A0ACM8FW06 LOC115318875 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037279|UniProtKB=A0ACM8EFS8 A0ACM8EFS8 LOC8037279 PTHR45632:SF40 LD33804P KELCH-LIKE PROTEIN 12 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8025461|UniProtKB=A0ACM8E0V6 A0ACM8E0V6 LOC8025461 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314982|UniProtKB=A0ACM8FRU4 A0ACM8FRU4 LOC115314982 PTHR18921:SF2 MYOSIN HEAVY CHAIN - RELATED THYROID RECEPTOR-INTERACTING PROTEIN 11 binding#GO:0005488;enzyme binding#GO:0019899;small GTPase binding#GO:0031267;protein binding#GO:0005515 vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;Golgi organization#GO:0007030;cellular localization#GO:0051641;establishment of localization#GO:0051234;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;transport#GO:0006810;Golgi vesicle transport#GO:0048193 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 actin or actin-binding cytoskeletal protein#PC00041;actin binding motor protein#PC00040 IXOSC|EnsemblGenome=LOC120843478|UniProtKB=A0ACM8EW86 A0ACM8EW86 LOC120843478 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042932|UniProtKB=A0ACM8EAF6 A0ACM8EAF6 LOC8042932 PTHR11616:SF334 SODIUM/CHLORIDE DEPENDENT TRANSPORTER SODIUM-DEPENDENT NUTRIENT AMINO ACID TRANSPORTER 1 amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;L-amino acid transmembrane transporter activity#GO:0015179;carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;solute:sodium symporter activity#GO:0015370;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324 neutral amino acid transport#GO:0015804;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;glycine transport#GO:0015816;import across plasma membrane#GO:0098739;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;sodium ion transport#GO:0006814;import into cell#GO:0098657;establishment of localization#GO:0051234;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;amino acid transport#GO:0006865;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8026967|UniProtKB=A0ACM8DY76 A0ACM8DY76 Ref1 PTHR19965:SF35 RNA AND EXPORT FACTOR BINDING PROTEIN THO COMPLEX SUBUNIT 4 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;metabolic process#GO:0008152;transport#GO:0006810;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleocytoplasmic transport#GO:0006913;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121837640|UniProtKB=A0ACM8G409 A0ACM8G409 LOC121837640 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037256|UniProtKB=A0ACM8EEA3 A0ACM8EEA3 Dlc90F PTHR21255:SF4 T-COMPLEX-ASSOCIATED-TESTIS-EXPRESSED 1/ DYNEIN LIGHT CHAIN DYNEIN LIGHT CHAIN TCTEX-TYPE protein binding#GO:0005515;binding#GO:0005488 cellular process#GO:0009987;microtubule-based movement#GO:0007018;microtubule-based process#GO:0007017 cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule cytoskeleton#GO:0015630;cytoplasmic dynein complex#GO:0005868;dynein complex#GO:0030286;organelle#GO:0043226;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8031584|UniProtKB=A0ACM8E0U0 A0ACM8E0U0 Chc PTHR10292:SF46 CLATHRIN HEAVY CHAIN RELATED CLATHRIN HEAVY CHAIN clathrin binding#GO:0030276;binding#GO:0005488;protein binding#GO:0005515 endocytosis#GO:0006897;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;receptor-mediated endocytosis#GO:0006898;localization#GO:0051179;import into cell#GO:0098657;establishment of localization#GO:0051234;transport#GO:0006810 organelle#GO:0043226;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;cell cortex#GO:0005938;vesicle#GO:0031982;coated membrane#GO:0048475;membrane coat#GO:0030117;endocytic vesicle#GO:0030139;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;cell periphery#GO:0071944;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle#GO:0030136 vesicle coat protein#PC00235;membrane traffic protein#PC00150 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Clathrin#P00738;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Clathrin#P00722 IXOSC|EnsemblGenome=LOC8054003|UniProtKB=A0ACM8DMM0 A0ACM8DMM0 sra PTHR10300:SF14 CALCIPRESSIN PROTEIN SARAH protein phosphatase regulator activity#GO:0019888;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208 cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;intracellular signaling cassette#GO:0141124;signaling#GO:0023052;biological regulation#GO:0065007;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;calcium-mediated signaling#GO:0019722 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC121047579|UniProtKB=A0ACM8G046 A0ACM8G046 LOC121047579 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8029976|UniProtKB=A0ACM8FEJ1 A0ACM8FEJ1 LOC8029976 PTHR24060:SF176 METABOTROPIC GLUTAMATE RECEPTOR TASTE RECEPTOR TYPE 1 MEMBER 2 signaling receptor activity#GO:0038023;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;transmembrane signaling receptor activity#GO:0004888;adenylate cyclase inhibiting G protein-coupled glutamate receptor activity#GO:0001640;glutamate receptor activity#GO:0008066 cell surface receptor signaling pathway#GO:0007166;regulation of trans-synaptic signaling#GO:0099177;biological regulation#GO:0065007;cellular process#GO:0009987;signal transduction#GO:0007165;cell communication#GO:0007154;regulation of synaptic transmission, glutamatergic#GO:0051966;glutamate receptor signaling pathway#GO:0007215;G protein-coupled receptor signaling pathway#GO:0007186;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115330680|UniProtKB=A0ACM8F1I0 A0ACM8F1I0 LOC115330680 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026773|UniProtKB=A0ACM8FV40 A0ACM8FV40 LOC8026773 PTHR45620:SF40 PDF RECEPTOR-LIKE PROTEIN-RELATED G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;signaling receptor activity#GO:0038023;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121838549|UniProtKB=A0ACM8G8G0 A0ACM8G8G0 LOC121838549 PTHR10334:SF517 CYSTEINE-RICH SECRETORY PROTEIN-RELATED SCP DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8030697|UniProtKB=A0ACM8EHG7 A0ACM8EHG7 Trs33 PTHR12817:SF0 TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 6B establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 Golgi apparatus#GO:0005794;intracellular protein-containing complex#GO:0140535;vesicle tethering complex#GO:0099023;cis-Golgi network#GO:0005801;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;TRAPP complex#GO:0030008;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8043582|UniProtKB=A0ACM8DGP8 A0ACM8DGP8 LOC8043582 PTHR47992:SF274 PROTEIN PHOSPHATASE PROTEIN PHOSPHATASE MN(2+)-DEPENDENT 1K phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 regulation of biological process#GO:0050789;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of intracellular signal transduction#GO:1902531 protein phosphatase#PC00195;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120847498|UniProtKB=A0ACM8F458 A0ACM8F458 LOC120847498 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326127|UniProtKB=A0ACM8E6G1 A0ACM8E6G1 LOC115326127 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023660|UniProtKB=A0ACM8E203 A0ACM8E203 LOC8023660 PTHR11042:SF183 EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824 reproductive process#GO:0022414;cell cycle#GO:0007049;meiotic cell cycle#GO:0051321;sexual reproduction#GO:0019953;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 non-receptor serine/threonine protein kinase#PC00167;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121836582|UniProtKB=A0ACM8FZA4 A0ACM8FZA4 LOC121836582 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121838134|UniProtKB=A0ACM8G7X2 A0ACM8G7X2 LOC121838134 PTHR46060:SF1 MARINER MOS1 TRANSPOSASE-LIKE PROTEIN MOS1 TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8038201|UniProtKB=A0ACM8DTV1 A0ACM8DTV1 LOC8038201 PTHR46318:SF3 UPSTREAM BINDING TRANSCRIPTION FACTOR NUCLEOLAR TRANSCRIPTION FACTOR 1 DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;core promoter sequence-specific DNA binding#GO:0001046;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;positive regulation of RNA metabolic process#GO:0051254;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase I#GO:0006356;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;macromolecule biosynthetic process#GO:0009059;positive regulation of cellular process#GO:0048522;regulation of macromolecule biosynthetic process#GO:0010556;transcription by RNA polymerase I#GO:0006360;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound metabolic process#GO:0006139;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;biosynthetic process#GO:0009058;positive regulation of transcription by RNA polymerase I#GO:0045943;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulation of biological process#GO:0050789;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;gene expression#GO:0010467;positive regulation of macromolecule metabolic process#GO:0010604;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 General transcription by RNA polymerase I#P00022>UBF1#P00655 IXOSC|EnsemblGenome=LOC121836137|UniProtKB=A0ACM8FXI1 A0ACM8FXI1 LOC121836137 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8035815|UniProtKB=A0ACM8EA51 A0ACM8EA51 Sarm PTHR22998:SF1 SARM1 NAD(+) HYDROLASE SARM1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;nucleoside phosphate catabolic process#GO:1901292;pyridine nucleotide catabolic process#GO:0019364;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;nucleotide metabolic process#GO:0009117;organophosphate catabolic process#GO:0046434;pyridine-containing compound metabolic process#GO:0072524;purine nucleotide catabolic process#GO:0006195;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound catabolic process#GO:0034655;organophosphate metabolic process#GO:0019637;NAD+ metabolic process#GO:0019674;nicotinamide nucleotide metabolic process#GO:0046496;cellular process#GO:0009987;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166 mitochondrion#GO:0005739;cell body#GO:0044297;cell projection#GO:0042995;neuronal cell body#GO:0043025;plasma membrane bounded cell projection#GO:0120025;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;dendritic tree#GO:0097447;dendrite#GO:0030425;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;neuron projection#GO:0043005;somatodendritic compartment#GO:0036477;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8050544|UniProtKB=A0ACM8G671 A0ACM8G671 LOC8050544 PTHR10185:SF17 PHOSPHOLIPASE D - RELATED GM01519P-RELATED phospholipase#PC00186 IXOSC|EnsemblGenome=LOC115310820|UniProtKB=A0ACM8DQ34 A0ACM8DQ34 LOC115310820 PTHR11579:SF9 PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN 1 S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;O-methyltransferase activity#GO:0008171;protein methyltransferase activity#GO:0008276;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a protein#GO:0140096 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC115308915|UniProtKB=A0ACM8ETN7 A0ACM8ETN7 LOC115308915 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8027814|UniProtKB=A0ACM8DSC1 A0ACM8DSC1 LOC8027814 PTHR19346:SF4 SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN SUGAR PHOSPHATE TRANSPORTER DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041136|UniProtKB=A0ACM8DYX3 A0ACM8DYX3 PTHR11827:SF73 SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS KAZACHOC, ISOFORM G symporter activity#GO:0015293;potassium ion transmembrane transporter activity#GO:0015079;monoatomic cation transmembrane transporter activity#GO:0008324;chloride transmembrane transporter activity#GO:0015108;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;solute:monoatomic cation symporter activity#GO:0015294;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 chloride transport#GO:0006821;transport#GO:0006810;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;inorganic anion transport#GO:0015698;monoatomic ion transport#GO:0006811;monoatomic anion transport#GO:0006820;cellular process#GO:0009987;potassium ion transport#GO:0006813;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;apical plasma membrane#GO:0016324;membrane#GO:0016020;apical part of cell#GO:0045177;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115331780|UniProtKB=A0ACM8ECR9 A0ACM8ECR9 LOC115331780 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023494|UniProtKB=A0ACM8DH75 A0ACM8DH75 LOC8023494 PTHR30605:SF0 ANHYDRO-N-ACETYLMURAMIC ACID KINASE ANHYDRO-N-ACETYLMURAMIC ACID KINASE kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824 kinase#PC00137;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120838691|UniProtKB=A0ACM8FZ68 A0ACM8FZ68 LOC120838691 PTHR10794:SF84 ABHYDROLASE DOMAIN-CONTAINING PROTEIN ESTERASE_LIPASE_THIOESTERASE FAMILY PROTEIN protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8032058|UniProtKB=A0ACM8F5D4 A0ACM8F5D4 LOC8032058 PTHR11214:SF349 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BETA-1,4-MANNOSYLGLYCOLIPID BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE BRN UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;sphingolipid biosynthetic process#GO:0030148;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121834646|UniProtKB=A0ACM8FQA9 A0ACM8FQA9 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC121833437|UniProtKB=A0ACM8FL39 A0ACM8FL39 LOC121833437 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834850|UniProtKB=A0ACM8FS16 A0ACM8FS16 LOC121834850 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8026499|UniProtKB=A0ACM8F8K9 A0ACM8F8K9 LOC8026499 PTHR11476:SF7 HISTIDYL-TRNA SYNTHETASE HISTIDINE--TRNA LIGASE ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity, acting on RNA#GO:0140098;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on a tRNA#GO:0140101;RNA binding#GO:0003723 protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;RNA metabolic process#GO:0016070;translation#GO:0006412;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation for protein translation#GO:0006418;tRNA aminoacylation#GO:0043039;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 aminoacyl-tRNA synthetase#PC00047;translational protein#PC00263 IXOSC|EnsemblGenome=LOC115322192|UniProtKB=A0ACM8F807 A0ACM8F807 LOC115322192 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034934|UniProtKB=A0ACM8EUP6 A0ACM8EUP6 l(2)gl PTHR10241:SF29 LETHAL 2 GIANT LARVAE PROTEIN LETHAL(2) GIANT LARVAE PROTEIN enzyme activator activity#GO:0008047;SNARE binding#GO:0000149;myosin binding#GO:0017022;cytoskeletal protein binding#GO:0008092;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;binding#GO:0005488;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;molecular function activator activity#GO:0140677;syntaxin binding#GO:0019905 localization#GO:0051179;cortical actin cytoskeleton organization#GO:0030866;secretion#GO:0046903;microtubule cytoskeleton organization#GO:0000226;cortical cytoskeleton organization#GO:0030865;organelle localization#GO:0051640;localization within membrane#GO:0051668;actin filament-based process#GO:0030029;regulation of Notch signaling pathway#GO:0008593;Golgi to plasma membrane transport#GO:0006893;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;cell cycle#GO:0007049;establishment of cell polarity#GO:0030010;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;regulation of response to stimulus#GO:0048583;transport#GO:0006810;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;establishment of spindle localization#GO:0051293;cellular localization#GO:0051641;spindle localization#GO:0051653;post-Golgi vesicle-mediated transport#GO:0006892;secretion by cell#GO:0032940;establishment or maintenance of cell polarity#GO:0007163;regulation of signaling#GO:0023051;establishment of organelle localization#GO:0051656;export from cell#GO:0140352;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cell cycle process#GO:0022402;cellular component organization or biogenesis#GO:0071840;exocytosis#GO:0006887;microtubule-based process#GO:0007017;establishment of spindle orientation#GO:0051294;Golgi vesicle transport#GO:0048193;regulation of establishment or maintenance of cell polarity#GO:0032878;vesicle-mediated transport#GO:0016192;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;cortical actin cytoskeleton#GO:0030864;cytoplasm#GO:0005737;actin cytoskeleton#GO:0015629;membrane#GO:0016020;cortical cytoskeleton#GO:0030863;cell cortex#GO:0005938;cell periphery#GO:0071944;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC115311218|UniProtKB=A0ACM8F9Y3 A0ACM8F9Y3 LOC115311218 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC120842553|UniProtKB=A0ACM8EV65 A0ACM8EV65 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835031|UniProtKB=A0ACM8FS54 A0ACM8FS54 LOC8023081 PTHR10880:SF48 MORTALITY FACTOR 4-LIKE PROTEIN MORTALITY FACTOR 4-LIKE PROTEIN 1 chromatin binding#GO:0003682;binding#GO:0005488 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794 cellular anatomical structure#GO:0110165;organelle#GO:0043226;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;acetyltransferase complex#GO:1902493;protein acetyltransferase complex#GO:0031248;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;H4 histone acetyltransferase complex#GO:1902562;NuA4 histone acetyltransferase complex#GO:0035267;chromatin#GO:0000785;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;transferase complex#GO:1990234 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8042457|UniProtKB=A0ACM8DU18 A0ACM8DU18 LOC8042457 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8037991|UniProtKB=A0ACM8FGX9 A0ACM8FGX9 LOC8037991 PTHR21261:SF15 BEAT PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC120839185|UniProtKB=A0ACM8EM58 A0ACM8EM58 Rpn6 PTHR10678:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11/COP9 SIGNALOSOME COMPLEX SUBUNIT 2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 11 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;catabolic process#GO:0009056;primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;peptidase complex#GO:1905368;proteasome complex#GO:0000502 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489;Cell cycle#P00013>Proteasome#P00480 IXOSC|EnsemblGenome=LOC8023611|UniProtKB=A0ACM8EFJ8 A0ACM8EFJ8 LOC8023611 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC115323465|UniProtKB=A0ACM8F592 A0ACM8F592 LOC115323465 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326526|UniProtKB=A0ACM8E7J3 A0ACM8E7J3 LOC115326526 PTHR45618:SF13 MITOCHONDRIAL DICARBOXYLATE CARRIER-RELATED MITOCHONDRIAL DICARBOXYLATE CARRIER transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;C4-dicarboxylate transmembrane transporter activity#GO:0015556;succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310 cellular process#GO:0009987;succinate transport#GO:0015744;carboxylic acid transmembrane transport#GO:1905039;phosphate ion transport#GO:0006817;dicarboxylic acid transport#GO:0006835;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;transport#GO:0006810;C4-dicarboxylate transport#GO:0015740;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;inorganic anion transport#GO:0015698 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8034714|UniProtKB=A0ACM8FLZ2 A0ACM8FLZ2 LOC8034714 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;methyltransferase activity#GO:0008168;transferase activity, transferring one-carbon groups#GO:0016741 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120837546|UniProtKB=A0ACM8EH63 A0ACM8EH63 LOC120837546 PTHR23080:SF149 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026717|UniProtKB=A0ACM8DWV0 A0ACM8DWV0 LOC8026717 PTHR39945:SF1 FI14129P FI14129P IXOSC|EnsemblGenome=LOC8029458|UniProtKB=A0ACM8E0M0 A0ACM8E0M0 Lamtor3 PTHR13378:SF1 REGULATOR COMPLEX PROTEIN LAMTOR3 RAGULATOR COMPLEX PROTEIN LAMTOR3 regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;regulation of intracellular signal transduction#GO:1902531;positive regulation of TOR signaling#GO:0032008;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;positive regulation of signal transduction#GO:0009967;regulation of cell communication#GO:0010646;cellular response to amino acid stimulus#GO:0071230;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;regulation of TORC1 signaling#GO:1903432;response to acid chemical#GO:0001101;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;positive regulation of TORC1 signaling#GO:1904263;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;response to chemical#GO:0042221;positive regulation of response to stimulus#GO:0048584 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;vacuolar membrane#GO:0005774;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;protein-containing complex#GO:0032991;guanyl-nucleotide exchange factor complex#GO:0032045;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115318742|UniProtKB=A0ACM8EI32 A0ACM8EI32 LOC115318742 PTHR37162:SF13 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035177|UniProtKB=A0ACM8EIB1 A0ACM8EIB1 TMS1 PTHR10383:SF9 SERINE INCORPORATOR SERINE INCORPORATOR, ISOFORM F cellular anatomical structure#GO:0110165;membrane#GO:0016020 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120851128|UniProtKB=A0ACM8FC67 A0ACM8FC67 LOC120851128 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8027189|UniProtKB=A0ACM8EIP5 A0ACM8EIP5 LOC8027189 PTHR11751:SF29 ALANINE AMINOTRANSFERASE ALANINE TRANSAMINASE transaminase#PC00216;transferase#PC00220 IXOSC|EnsemblGenome=LOC121837585|UniProtKB=A0ACM8G440 A0ACM8G440 LOC121837585 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046794|UniProtKB=A0ACM8FRP4 A0ACM8FRP4 LOC121046794 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC115311154|UniProtKB=A0ACM8DQJ4 A0ACM8DQJ4 LOC115311154 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115314381|UniProtKB=A0ACM8DU24 A0ACM8DU24 LOC115314381 PTHR23234:SF12 ZNF44 PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121835726|UniProtKB=A0ACM8FWN2 A0ACM8FWN2 LOC121835726 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051184|UniProtKB=A0ACM8E5J6 A0ACM8E5J6 LOC8051184 PTHR15071:SF29 MANNOSE-6-PHOSPHATE RECEPTOR FAMILY MEMBER CATION-DEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR binding#GO:0005488;protein-containing complex binding#GO:0044877 protein localization to lysosome#GO:0061462;establishment of protein localization to vacuole#GO:0072666;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;lysosomal transport#GO:0007041;protein localization to vacuole#GO:0072665;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular protein transport#GO:0006886;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endosome#GO:0005768;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;Golgi apparatus subcompartment#GO:0098791;endomembrane system#GO:0012505;late endosome#GO:0005770;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8040365|UniProtKB=A0ACM8DYB5 A0ACM8DYB5 LOC8040365 PTHR10907:SF47 REGUCALCIN REGUCALCIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788 regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of calcium-mediated signaling#GO:0050848;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 esterase#PC00097;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120847589|UniProtKB=A0ACM8F4B6 A0ACM8F4B6 LOC120847589 PTHR43881:SF1 GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) GAMMA-GLUTAMYLTRANSPEPTIDASE (AFU_ORTHOLOGUE AFUA_4G13580) protease#PC00190 IXOSC|EnsemblGenome=LOC8028848|UniProtKB=A0ACM8DHA6 A0ACM8DHA6 LOC8028848 PTHR24340:SF37 HOMEOBOX PROTEIN NKX HOMEOBOX PROTEIN SLOU sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 cellular process#GO:0009987;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;developmental process#GO:0032502;regulation of gene expression#GO:0010468;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8051477|UniProtKB=A0ACM8E4R3 A0ACM8E4R3 LOC8051477 PTHR19290:SF162 BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR AMOS-RELATED transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of biosynthetic process#GO:0009891;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;plasma membrane bounded cell projection organization#GO:0120036;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;axon development#GO:0061564;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;sensory organ development#GO:0007423;developmental process#GO:0032502;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;cell projection organization#GO:0030030;cell development#GO:0048468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;neuron development#GO:0048666;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;positive regulation of macromolecule metabolic process#GO:0010604;nervous system development#GO:0007399;neuron projection development#GO:0031175;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;animal organ development#GO:0048513;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;positive regulation of transcription by RNA polymerase II#GO:0045944;neuron differentiation#GO:0030182 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8038159|UniProtKB=A0ACM8DWX1 A0ACM8DWX1 LOC8038159 PTHR46814:SF1 EGALITARIAN, ISOFORM B EGALITARIAN, ISOFORM B mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 localization#GO:0051179;RNA localization#GO:0006403;macromolecule localization#GO:0033036 IXOSC|EnsemblGenome=LOC115327718|UniProtKB=A0ACM8EM89 A0ACM8EM89 LOC115327718 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038994|UniProtKB=A0ACM8DMR3 A0ACM8DMR3 Blos2 PTHR46479:SF1 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX 1 SUBUNIT 2 protein binding#GO:0005515;binding#GO:0005488;cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631 vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;lysosome localization#GO:0032418;establishment of localization in cell#GO:0051649;endosomal transport#GO:0016197;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;transport#GO:0006810;intracellular transport#GO:0046907;organelle localization#GO:0051640 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;BLOC-1 complex#GO:0031083;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815 IXOSC|EnsemblGenome=LOC115326762|UniProtKB=A0ACM8E6C6 A0ACM8E6C6 CRMP PTHR11647:SF1 HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER DIHYDROPYRIMIDINASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;dihydropyrimidinase activity#GO:0004157 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase metabolic process#GO:0009112;pyrimidine nucleobase metabolic process#GO:0006206;cellular process#GO:0009987;pyrimidine-containing compound metabolic process#GO:0072527;primary metabolic process#GO:0044238;pyrimidine nucleobase catabolic process#GO:0006208;nucleobase catabolic process#GO:0046113;nucleobase-containing compound metabolic process#GO:0006139;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 hydrolase#PC00121 Axon guidance mediated by semaphorins#P00007>CRMP#P00339;Pyrimidine Metabolism#P02771>Dihydropyrimidinase#P03125 IXOSC|EnsemblGenome=LOC115331749|UniProtKB=A0ACM8F7S3 A0ACM8F7S3 LOC115331749 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120837249|UniProtKB=A0ACM8EHX9 A0ACM8EHX9 LOC120837249 PTHR23428:SF386 HISTONE H2B HISTONE H2B 1-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120842857|UniProtKB=A0ACM8EUS9 A0ACM8EUS9 LOC120842857 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115317037|UniProtKB=A0ACM8EU83 A0ACM8EU83 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE transferase#PC00220;methyltransferase#PC00155 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC120847345|UniProtKB=A0ACM8FGA8 A0ACM8FGA8 LOC120847345 PTHR22803:SF124 MANNOSE, PHOSPHOLIPASE, LECTIN RECEPTOR RELATED ACCESSORY GLAND PROTEIN ACP29AB-RELATED membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC120840977|UniProtKB=A0ACM8EQY7 A0ACM8EQY7 LOC120840977 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8034807|UniProtKB=A0ACM8DPK1 A0ACM8DPK1 LOC8034807 PTHR43176:SF38 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL hydrolase activity#GO:0016787;catalytic activity#GO:0003824;deacylase activity#GO:0160215;acyl-CoA hydrolase activity#GO:0016289;fatty acyl-CoA hydrolase activity#GO:0047617;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120844666|UniProtKB=A0ACM8EYZ2 A0ACM8EYZ2 LOC120844666 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme regulator activity#GO:0030234;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;peptidase regulator activity#GO:0061134;endopeptidase inhibitor activity#GO:0004866;molecular function regulator activity#GO:0098772;enzyme inhibitor activity#GO:0004857 protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8029347|UniProtKB=A0ACM8DI18 A0ACM8DI18 mRpL16 PTHR12220:SF13 50S/60S RIBOSOMAL PROTEIN L16 LARGE RIBOSOMAL SUBUNIT PROTEIN UL16M RNA binding#GO:0003723;structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735;binding#GO:0005488;rRNA binding#GO:0019843;nucleic acid binding#GO:0003676 mitochondrial translation#GO:0032543;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;organellar ribosome#GO:0000313;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;membrane-bounded organelle#GO:0043227;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229 ribosomal protein#PC00202 Oxytocin receptor mediated signaling pathway#P04391>SNARE Complex#P04532;5HT3 type receptor mediated signaling pathway#P04375>SNARE Complex#P04423;Opioid prodynorphin pathway#P05916>SNARE Complex#P05996;Beta2 adrenergic receptor signaling pathway#P04378>SNARE Complex#P04442;Dopamine receptor mediated signaling pathway#P05912>SNARE Complex#P05956;Thyrotropin-releasing hormone receptor signaling pathway#P04394>SNARE Complex#P04582;Beta3 adrenergic receptor signaling pathway#P04379>SNARE Complex#P04447;Cortocotropin releasing factor receptor signaling pathway#P04380>SNARE Complex#P04457;Beta1 adrenergic receptor signaling pathway#P04377>SNARE Complex#P04435;5HT1 type receptor mediated signaling pathway#P04373>SNARE Complex#P04405;5HT4 type receptor mediated signaling pathway#P04376>SNARE Complex#P04428;5HT2 type receptor mediated signaling pathway#P04374>SNARE Complex#P04415;Opioid proenkephalin pathway#P05915>SNARE Complex#P05986;Opioid proopiomelanocortin pathway#P05917>SNARE Complex#P06005 IXOSC|EnsemblGenome=LOC115324969|UniProtKB=A0ACM8F384 A0ACM8F384 LOC115324969 PTHR18934:SF277 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX8 helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543;RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657 RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;RNA splicing#GO:0008380 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115314784|UniProtKB=A0ACM8DUM5 A0ACM8DUM5 LOC115314784 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052267|UniProtKB=A0ACM8DM44 A0ACM8DM44 bug PTHR14684:SF2 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 15 cellular component organization or biogenesis#GO:0071840;cilium organization#GO:0044782;organelle assembly#GO:0070925;plasma membrane bounded cell projection assembly#GO:0120031;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection organization#GO:0120036;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular component organization#GO:0016043;cilium assembly#GO:0060271;cell projection assembly#GO:0030031;cellular process#GO:0009987 cilium#GO:0005929;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025 IXOSC|EnsemblGenome=LOC8023598|UniProtKB=A0ACM8DHB3 A0ACM8DHB3 LOC8023598 PTHR14095:SF0 PHOSPHATASE 2A REGULATORY SUBUNIT-RELATED MIP22305P phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287;protein-containing complex#GO:0032991 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629 IXOSC|EnsemblGenome=LOC8028894|UniProtKB=A0ACM8E6V7 A0ACM8E6V7 LOC8028894 PTHR47526:SF4 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115314048|UniProtKB=A0ACM8DTM6 A0ACM8DTM6 LOC115314048 PTHR48548:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120842984|UniProtKB=A0ACM8G5W9 A0ACM8G5W9 LOC120842984 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8031834|UniProtKB=A0ACM8DQ94 A0ACM8DQ94 LOC8031834 PTHR23119:SF44 DISCS LARGE PROTEIN LAP4 binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;protein binding#GO:0005515 endocytic recycling#GO:0032456;protein localization to membrane#GO:0072657;cellular localization#GO:0051641;protein transport#GO:0015031;regulation of biological quality#GO:0065008;establishment or maintenance of cell polarity#GO:0007163;cell adhesion#GO:0007155;receptor clustering#GO:0043113;vesicle-mediated transport#GO:0016192;cell-cell adhesion#GO:0098609;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to synapse#GO:0035418;neurotransmitter receptor transport to postsynaptic membrane#GO:0098969;endosomal transport#GO:0016197;protein localization to cell periphery#GO:1990778;intracellular protein transport#GO:0006886;protein localization to plasma membrane#GO:0072659;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;establishment or maintenance of apical/basal cell polarity#GO:0035088;protein localization to cell junction#GO:1902414;establishment or maintenance of bipolar cell polarity#GO:0061245;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;biological regulation#GO:0065007;macromolecule localization#GO:0033036;endosome to plasma membrane protein transport#GO:0099638;establishment of localization#GO:0051234;vesicle-mediated transport to the plasma membrane#GO:0098876;intracellular protein localization#GO:0008104;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;intracellular transport#GO:0046907;transport#GO:0006810 basal plasma membrane#GO:0009925;cell periphery#GO:0071944;basolateral plasma membrane#GO:0016323;cell-cell junction#GO:0005911;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;synaptic membrane#GO:0097060;adherens junction#GO:0005912;cell junction#GO:0030054;basal part of cell#GO:0045178;postsynapse#GO:0098794;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;anchoring junction#GO:0070161 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115325432|UniProtKB=A0ACM8EZ58 A0ACM8EZ58 LOC115325432 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037931|UniProtKB=A0ACM8G2I3 A0ACM8G2I3 LOC8037931 PTHR23226:SF452 ZINC FINGER AND SCAN DOMAIN-CONTAINING PAG-3 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8027266|UniProtKB=A0ACM8DIW5 A0ACM8DIW5 LOC8027266 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8027750|UniProtKB=A0ACM8E4C6 A0ACM8E4C6 LOC8027750 PTHR45632:SF34 LD33804P KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115332676|UniProtKB=A0ACM8EEU6 A0ACM8EEU6 LOC115332676 PTHR24350:SF34 SERINE/THREONINE-PROTEIN KINASE IAL-RELATED AURORA KINASE protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;catalytic activity#GO:0003824;transferase activity#GO:0016740 microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of cell cycle process#GO:0010564;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;microtubule cytoskeleton organization#GO:0000226;cell cycle process#GO:0022402;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;regulation of cell cycle#GO:0051726;mitotic spindle organization#GO:0007052;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278 protein-containing complex#GO:0032991;microtubule associated complex#GO:0005875;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;spindle pole#GO:0000922;kinetochore#GO:0000776;spindle microtubule#GO:0005876;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;spindle midzone#GO:0051233;chromosomal region#GO:0098687;supramolecular fiber#GO:0099512;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC120843640|UniProtKB=A0ACM8EWM5 A0ACM8EWM5 LOC120843640 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8044108|UniProtKB=A0ACM8DL54 A0ACM8DL54 Ttc30 PTHR20931:SF0 TETRATRICOPEPTIDE REPEAT PROTEIN 30 TETRATRICOPEPTIDE REPEAT PROTEIN 30 binding#GO:0005488;protein-containing complex binding#GO:0044877 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;transport along microtubule#GO:0010970;establishment of localization#GO:0051234;cellular component organization#GO:0016043;intraciliary transport#GO:0042073;cell projection organization#GO:0030030;microtubule-based movement#GO:0007018;microtubule-based transport#GO:0099111;cilium organization#GO:0044782;localization#GO:0051179;cellular localization#GO:0051641 microtubule cytoskeleton#GO:0015630;supramolecular polymer#GO:0099081;protein-containing complex#GO:0032991;ciliary plasm#GO:0097014;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intraciliary transport particle B#GO:0030992;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;cytoplasmic microtubule#GO:0005881;axonemal microtubule#GO:0005879;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;intraciliary transport particle#GO:0030990;intracellular organelle#GO:0043229;cilium#GO:0005929;axoneme#GO:0005930;microtubule#GO:0005874;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;supramolecular fiber#GO:0099512 IXOSC|EnsemblGenome=LOC8027804|UniProtKB=A0ACM8DJC4 A0ACM8DJC4 LOC8027804 PTHR11467:SF36 HISTONE H1 H1.010 LINKER HISTONE, CLUSTER MEMBER-RELATED chromatin binding#GO:0003682;nucleic acid binding#GO:0003676;binding#GO:0005488;double-stranded DNA binding#GO:0003690;nucleosome binding#GO:0031491;protein-containing complex binding#GO:0044877;DNA binding#GO:0003677;chromatin DNA binding#GO:0031490 negative regulation of metabolic process#GO:0009892;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of DNA recombination#GO:0045910;chromosome condensation#GO:0030261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of DNA recombination#GO:0000018;biological regulation#GO:0065007;negative regulation of DNA metabolic process#GO:0051053;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;negative regulation of cellular process#GO:0048523 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8043786|UniProtKB=A0ACM8FA69 A0ACM8FA69 LOC8043786 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;fatty acid metabolic process#GO:0006631;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 membrane#GO:0016020;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8029126|UniProtKB=A0ACM8EJB3 A0ACM8EJB3 Alg1 PTHR13036:SF0 BETA1,4 MANNOSYLTRANSFERASE CHITOBIOSYLDIPHOSPHODOLICHOL BETA-MANNOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;mannosyltransferase activity#GO:0000030;transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758 protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;glycoprotein metabolic process#GO:0009100;metabolic process#GO:0008152;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;primary metabolic process#GO:0044238;glycoprotein biosynthetic process#GO:0009101 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115319567|UniProtKB=A0ACM8EYJ6 A0ACM8EYJ6 LOC115319567 PTHR16515:SF88 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8034707|UniProtKB=A0ACM8F619 A0ACM8F619 LOC8034707 PTHR23042:SF107 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS FI10506P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;basic helix-loop-helix transcription factor#PC00055 IXOSC|EnsemblGenome=LOC8032391|UniProtKB=A0ACM8DRA1 A0ACM8DRA1 gw PTHR13020:SF25 TRINUCLEOTIDE REPEAT-CONTAINING GENE 6 PROTEIN GAWKY post-transcriptional gene silencing#GO:0016441;regulatory ncRNA-mediated post-transcriptional gene silencing#GO:0035194;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of metabolic process#GO:0009893;negative regulation of gene expression#GO:0010629;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;miRNA-mediated post-transcriptional gene silencing#GO:0035195;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;positive regulation of mRNA metabolic process#GO:1903313;regulation of mRNA metabolic process#GO:1903311;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604 intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8024123|UniProtKB=A0ACM8DXI6 A0ACM8DXI6 LOC8024123 PTHR18929:SF210 PROTEIN DISULFIDE ISOMERASE PROTEIN DISULFIDE-ISOMERASE A4 protein disulfide isomerase activity#GO:0003756;catalytic activity#GO:0003824;isomerase activity#GO:0016853;intramolecular oxidoreductase activity#GO:0016860;catalytic activity, acting on a protein#GO:0140096 response to stimulus#GO:0050896;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457;primary metabolic process#GO:0044238;response to stress#GO:0006950;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cell surface#GO:0009986;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115320072|UniProtKB=A0ACM8ER97 A0ACM8ER97 LOC115320072 PTHR24394:SF67 ZINC FINGER PROTEIN MYONEURIN DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8038541|UniProtKB=A0ACM8FYV3 A0ACM8FYV3 LOC8038541 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC8053041|UniProtKB=A0ACM8DPX9 A0ACM8DPX9 LOC8053041 PTHR23423:SF10 ORGANIC SOLUTE TRANSPORTER-RELATED TRANSMEMBRANE PROTEIN 184C transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8035642|UniProtKB=A0ACM8FRA4 A0ACM8FRA4 LOC8035642 PTHR21676:SF1 PROTEIN STUM PROTEIN STUM HOMOLOG IXOSC|EnsemblGenome=LOC8041561|UniProtKB=A0ACM8DKN4 A0ACM8DKN4 DNAlig4 PTHR45997:SF3 DNA LIGASE 4 DNA LIGASE 4 carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;ligase activity#GO:0016874;ribonucleotide binding#GO:0032553;purine ribonucleotide binding#GO:0032555;catalytic activity, acting on DNA#GO:0140097;heterocyclic compound binding#GO:1901363;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ion binding#GO:0043167;small molecule binding#GO:0036094;nucleic acid binding#GO:0003676;anion binding#GO:0043168;DNA binding#GO:0003677 nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;response to stress#GO:0006950;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;double-strand break repair via nonhomologous end joining#GO:0006303;DNA damage response#GO:0006974;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stress#GO:0033554 nucleus#GO:0005634;DNA repair complex#GO:1990391;intracellular membrane-bounded organelle#GO:0043231;nonhomologous end joining complex#GO:0070419;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121045770|UniProtKB=A0ACM8FC84 A0ACM8FC84 LOC121045770 PTHR13456:SF0 UPF0729 PROTEIN C18ORF32 UPF0729 PROTEIN C18ORF32 IXOSC|EnsemblGenome=LOC120848613|UniProtKB=A0ACM8F729 A0ACM8F729 LOC120848613 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120844719|UniProtKB=A0ACM8EZJ9 A0ACM8EZJ9 LOC120844719 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121838334|UniProtKB=A0ACM8G8Q7 A0ACM8G8Q7 LOC121838334 PTHR47331:SF10 PHD-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040615|UniProtKB=A0ACM8DNK4 A0ACM8DNK4 PIG-Z PTHR22760:SF3 GLYCOSYLTRANSFERASE GPI ALPHA-1,2-MANNOSYLTRANSFERASE 4 hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824;mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;GPI anchored protein biosynthesis#GO:0180046;glycerolipid metabolic process#GO:0046486;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170 endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115316026|UniProtKB=A0ACM8DW44 A0ACM8DW44 LOC115316026 PTHR32297:SF1 SODIUM CHANNEL MODIFIER 1 SODIUM CHANNEL MODIFIER 1 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleic acid biosynthetic process#GO:0141187;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 transporter#PC00227;ion channel#PC00133 IXOSC|EnsemblGenome=LOC8029043|UniProtKB=A0ACM8E1X9 A0ACM8E1X9 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593;biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053646|UniProtKB=A0ACM8DSZ7 A0ACM8DSZ7 PTHR15948:SF8 G-PROTEIN COUPLED RECEPTOR 89-RELATED GOLGI PH REGULATOR A-RELATED passive transmembrane transporter activity#GO:0022803;monoatomic anion transmembrane transporter activity#GO:0008509;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;voltage-gated monoatomic anion channel activity#GO:0008308;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic anion channel activity#GO:0005253;voltage-gated channel activity#GO:0022832;channel activity#GO:0015267 homeostatic process#GO:0042592;biological regulation#GO:0065007;intracellular monoatomic ion homeostasis#GO:0006873;monoatomic ion homeostasis#GO:0050801;intracellular chemical homeostasis#GO:0055082;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;regulation of intracellular pH#GO:0051453;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;regulation of pH#GO:0006885 membrane#GO:0016020;cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;endoplasmic reticulum membrane#GO:0005789;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;intracellular membrane-bounded organelle#GO:0043231;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC121835369|UniProtKB=A0ACM8FUB0 A0ACM8FUB0 LOC121835369 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC120842038|UniProtKB=A0ACM8ET07 A0ACM8ET07 LOC120842038 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120849247|UniProtKB=A0ACM8F6E7 A0ACM8F6E7 LOC120849247 PTHR10426:SF88 STRICTOSIDINE SYNTHASE-RELATED ADIPOCYTE PLASMA MEMBRANE-ASSOCIATED PROTEIN HEMOMUCIN-RELATED catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC115312641|UniProtKB=A0ACM8FQY4 A0ACM8FQY4 LOC115312641 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC120837364|UniProtKB=A0ACM8EI64 A0ACM8EI64 LOC120837364 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026437|UniProtKB=A0ACM8DSK6 A0ACM8DSK6 LOC8026437 PTHR10166:SF68 VOLTAGE-DEPENDENT CALCIUM CHANNEL SUBUNIT ALPHA-2/DELTA-RELATED VWFA AND CACHE DOMAIN-CONTAINING PROTEIN 1 voltage-gated calcium channel activity#GO:0005245;channel activity#GO:0015267;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;calcium channel activity#GO:0005262;voltage-gated channel activity#GO:0022832;calcium ion transmembrane transporter activity#GO:0015085;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;voltage-gated calcium channel complex#GO:0005891;calcium channel complex#GO:0034704;cell periphery#GO:0071944;plasma membrane protein complex#GO:0098797;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;cation channel complex#GO:0034703 transporter#PC00227;voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC121837646|UniProtKB=A0ACM8G5R4 A0ACM8G5R4 LOC121837646 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115330109|UniProtKB=A0ACM8F168 A0ACM8F168 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8025460|UniProtKB=A0ACM8E2Z9 A0ACM8E2Z9 LOC8025460 PTHR12352:SF3 SECRETED MODULAR CALCIUM-BINDING PROTEIN NIDOGEN-2 cellular process#GO:0009987;cell-matrix adhesion#GO:0007160;cell adhesion#GO:0007155;cell-substrate adhesion#GO:0031589 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;basement membrane#GO:0005604 calmodulin-related#PC00061 IXOSC|EnsemblGenome=LOC8028177|UniProtKB=A0ACM8E5G6 A0ACM8E5G6 LOC8028177 PTHR10264:SF136 BAND 7 PROTEIN-RELATED BAND 7 DOMAIN-CONTAINING PROTEIN ion channel regulator activity#GO:0099106;ion channel inhibitor activity#GO:0008200;transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120841034|UniProtKB=A0ACM8ERT3 A0ACM8ERT3 LOC120841034 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115326240|UniProtKB=A0ACM8EYN0 A0ACM8EYN0 LOC115326240 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC115319978|UniProtKB=A0ACM8DZQ9 A0ACM8DZQ9 LOC115319978 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC8042465|UniProtKB=A0ACM8DSW2 A0ACM8DSW2 LOC8042465 PTHR14907:SF2 FI14130P SUPPRESSOR APC DOMAIN-CONTAINING PROTEIN 2 IXOSC|EnsemblGenome=LOC8038327|UniProtKB=A0ACM8E4A3 A0ACM8E4A3 LOC8038327 PTHR45728:SF9 ACETYL-COA CARBOXYLASE, ISOFORM A ACETYL-COA CARBOXYLASE, ISOFORM A ligase activity#GO:0016874;catalytic activity#GO:0003824 monocarboxylic acid biosynthetic process#GO:0072330;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8036879|UniProtKB=A0ACM8EDA7 A0ACM8EDA7 LOC8036879 PTHR11142:SF5 PSEUDOURIDYLATE SYNTHASE TRNA PSEUDOURIDINE(38_39) SYNTHASE isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;intramolecular transferase activity#GO:0016866 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA modification#GO:0016556;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 lyase#PC00144 IXOSC|EnsemblGenome=LOC8036479|UniProtKB=A0ACM8G7D7 A0ACM8G7D7 LOC8036479 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8038608|UniProtKB=A0ACM8FBB5 A0ACM8FBB5 LOC8038608 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC121836210|UniProtKB=A0ACM8FXG3 A0ACM8FXG3 LOC121836210 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8027843|UniProtKB=A0ACM8DNX5 A0ACM8DNX5 LOC8027843 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8052244|UniProtKB=A0ACM8EA66 A0ACM8EA66 LOC8052244 PTHR10529:SF344 AP COMPLEX SUBUNIT MU PROTEIN STONED-B molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;cargo adaptor activity#GO:0140312 intracellular transport#GO:0046907;synaptic vesicle cycle#GO:0099504;Golgi vesicle transport#GO:0048193;transport#GO:0006810;vacuolar transport#GO:0007034;regulation of endocytosis#GO:0030100;establishment of localization#GO:0051234;import into cell#GO:0098657;vesicle-mediated transport in synapse#GO:0099003;regulation of transport#GO:0051049;receptor-mediated endocytosis#GO:0006898;regulation of localization#GO:0032879;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;synaptic vesicle recycling#GO:0036465;biological regulation#GO:0065007;Golgi to vacuole transport#GO:0006896;cellular localization#GO:0051641;localization#GO:0051179;post-Golgi vesicle-mediated transport#GO:0006892;synaptic vesicle endocytosis#GO:0048488;clathrin-dependent endocytosis#GO:0072583;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;endocytosis#GO:0006897;regulation of cellular component organization#GO:0051128 membrane coat#GO:0030117;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;synaptic vesicle#GO:0008021;plasma membrane protein complex#GO:0098797;vesicle#GO:0031982;organelle membrane#GO:0031090;clathrin-coated vesicle#GO:0030136;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;transport vesicle#GO:0030133;plasma membrane#GO:0005886;membrane#GO:0016020;Golgi apparatus subcompartment#GO:0098791;cytosol#GO:0005829;vesicle membrane#GO:0012506;cell periphery#GO:0071944;coated membrane#GO:0048475;coated vesicle#GO:0030135;organelle subcompartment#GO:0031984;endocytic vesicle#GO:0030139;exocytic vesicle#GO:0070382;intracellular organelle#GO:0043229;clathrin coat#GO:0030118;cellular anatomical structure#GO:0110165;synapse#GO:0045202;organelle#GO:0043226;coated vesicle membrane#GO:0030662;clathrin-coated pit#GO:0005905;intracellular vesicle#GO:0097708;clathrin-coated endocytic vesicle#GO:0045334;clathrin-coated vesicle membrane#GO:0030665;cell junction#GO:0030054;bounding membrane of organelle#GO:0098588;AP-type membrane coat adaptor complex#GO:0030119;clathrin vesicle coat#GO:0030125;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;trans-Golgi network#GO:0005802;cytoplasm#GO:0005737;vesicle coat#GO:0030120;secretory vesicle#GO:0099503;presynapse#GO:0098793 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8039213|UniProtKB=A0ACM8DKD2 A0ACM8DKD2 LOC8039213 PTHR48082:SF2 ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL ATP SYNTHASE F(1) COMPLEX SUBUNIT ALPHA, MITOCHONDRIAL ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;catalytic activity#GO:0003824;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;nucleotide binding#GO:0000166;proton channel activity#GO:0015252;nucleoside phosphate binding#GO:1901265;ATP binding#GO:0005524;binding#GO:0005488;monoatomic cation transmembrane transporter activity#GO:0008324;proton-transporting ATP synthase activity, rotational mechanism#GO:0046933;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;proton transmembrane transporter activity#GO:0015078;transporter activity#GO:0005215;ligase activity#GO:0016874;ribonucleotide binding#GO:0032553;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 small molecule metabolic process#GO:0044281;phosphorus metabolic process#GO:0006793;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribonucleotide metabolic process#GO:0009259;ribose phosphate biosynthetic process#GO:0046390;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ATP metabolic process#GO:0046034;carbohydrate derivative biosynthetic process#GO:1901137;ribonucleoside triphosphate biosynthetic process#GO:0009201;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;ATP biosynthetic process#GO:0006754;purine nucleoside triphosphate biosynthetic process#GO:0009145;proton motive force-driven ATP synthesis#GO:0015986;nucleoside phosphate metabolic process#GO:0006753;nucleoside triphosphate metabolic process#GO:0009141;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;organophosphate biosynthetic process#GO:0090407;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;purine ribonucleoside triphosphate biosynthetic process#GO:0009206;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleoside triphosphate biosynthetic process#GO:0009142;carbohydrate derivative metabolic process#GO:1901135;purine ribonucleoside triphosphate metabolic process#GO:0009205;nucleoside phosphate biosynthetic process#GO:1901293 transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;proton-transporting two-sector ATPase complex#GO:0016469;catalytic complex#GO:1902494;cation channel complex#GO:0034703;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;proton-transporting ATP synthase complex#GO:0045259;respiratory chain complex#GO:0098803;membrane#GO:0016020;membrane protein complex#GO:0098796 ATP synthase#PC00002;primary active transporter#PC00068 ATP synthesis#P02721>F1 alpha#P02791 IXOSC|EnsemblGenome=LOC8028011|UniProtKB=A0ACM8E408 A0ACM8E408 LOC8028011 PTHR46130:SF3 LAMGL DOMAIN-CONTAINING PROTEIN PAPPALYSIN-1 catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 cellular process#GO:0009987;proteolysis#GO:0006508;metabolic process#GO:0008152;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8052834|UniProtKB=A0ACM8DWZ8 A0ACM8DWZ8 LOC8052834 PTHR11264:SF0 URACIL-DNA GLYCOSYLASE URACIL-DNA GLYCOSYLASE DNA N-glycosylase activity#GO:0019104;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity, acting on DNA#GO:0140097 nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;response to stress#GO:0006950;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 DNA glycosylase#PC00010 IXOSC|EnsemblGenome=LOC121835333|UniProtKB=A0ACM8FTH8 A0ACM8FTH8 LOC121835333 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318210|UniProtKB=A0ACM8DY90 A0ACM8DY90 LOC115318210 PTHR10907:SF47 REGUCALCIN REGUCALCIN catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of biological process#GO:0050789;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of calcium-mediated signaling#GO:0050848;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634 metabolite interconversion enzyme#PC00262;esterase#PC00097 IXOSC|EnsemblGenome=LOC8033221|UniProtKB=A0ACM8DZ65 A0ACM8DZ65 Pus10 PTHR21568:SF0 TRNA PSEUDOURIDINE SYNTHASE PUS10 TRNA PSEUDOURIDINE SYNTHASE PUS10 catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;isomerase activity#GO:0016853;intramolecular transferase activity#GO:0016866;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;primary miRNA processing#GO:0031053;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulatory ncRNA-mediated gene silencing#GO:0031047;negative regulation of cellular process#GO:0048523;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;pseudouridine synthesis#GO:0001522;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8051726|UniProtKB=A0ACM8E2Y5 A0ACM8E2Y5 Rab1 PTHR47977:SF116 RAS-RELATED PROTEIN RAB RAB GTPASE-RELATED small molecule binding#GO:0036094;anion binding#GO:0043168;ion binding#GO:0043167;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;carbohydrate derivative binding#GO:0097367;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120848787|UniProtKB=A0ACM8F6H1 A0ACM8F6H1 PTHR33198:SF27 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC115323759|UniProtKB=A0ACM8FJC4 A0ACM8FJC4 LOC115323759 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115332949|UniProtKB=A0ACM8FJZ9 A0ACM8FJZ9 LOC115332949 PTHR24394:SF62 ZINC FINGER PROTEIN SUBFAMILY NOT NAMED C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8040381|UniProtKB=A0ACM8F815 A0ACM8F815 LOC8040381 PTHR24064:SF577 SOLUTE CARRIER FAMILY 22 MEMBER FI24011P1-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115311466|UniProtKB=A0ACM8G6H9 A0ACM8G6H9 LOC115311466 PTHR43340:SF1 HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;glycosyltransferase activity#GO:0016757;pentosyltransferase activity#GO:0016763;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;magnesium ion binding#GO:0000287;cation binding#GO:0043169;metal ion binding#GO:0046872 organophosphate biosynthetic process#GO:0090407;IMP biosynthetic process#GO:0006188;nucleoside phosphate metabolic process#GO:0006753;nucleoside monophosphate metabolic process#GO:0009123;IMP metabolic process#GO:0046040;primary metabolic process#GO:0044238;nucleobase metabolic process#GO:0009112;nucleoside phosphate biosynthetic process#GO:1901293;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide biosynthetic process#GO:0009260;organophosphate metabolic process#GO:0019637;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide biosynthetic process#GO:0006164;purine-containing compound biosynthetic process#GO:0072522;nucleoside monophosphate biosynthetic process#GO:0009124;purine ribonucleoside monophosphate metabolic process#GO:0009167;small molecule metabolic process#GO:0044281;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside monophosphate metabolic process#GO:0009126;carbohydrate derivative biosynthetic process#GO:1901137;purine nucleobase metabolic process#GO:0006144;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;ribose phosphate biosynthetic process#GO:0046390 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 Xanthine and guanine salvage pathway#P02788>Guanine phosphoribosyl transferase#P03245;Adenine and hypoxanthine salvage pathway#P02723>Hypoxanthine phosphoribosyl transferase#P02804;Xanthine and guanine salvage pathway#P02788>Xanthine phosphoribosyl transferase#P03247;Salvage pyrimidine ribonucleotides#P02775>Uracil phosphoribosyl transferase#P03151 IXOSC|EnsemblGenome=LOC8043427|UniProtKB=A0ACM8E259 A0ACM8E259 LOC8043427 PTHR21050:SF1 MIDKINE AND PLEIOTROPHIN 1, ISOFORM A-RELATED MIDKINE AND PLEIOTROPHIN 1, ISOFORM A-RELATED heparin binding#GO:0008201;binding#GO:0005488;carbohydrate derivative binding#GO:0097367;glycosaminoglycan binding#GO:0005539 anatomical structure morphogenesis#GO:0009653;mesoderm morphogenesis#GO:0048332;tissue development#GO:0009888;multicellular organismal process#GO:0032501;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;tissue morphogenesis#GO:0048729;anatomical structure development#GO:0048856;mesoderm development#GO:0007498 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC120849440|UniProtKB=A0ACM8F844 A0ACM8F844 LOC120849440 PTHR21719:SF2 FI06402P-RELATED FI06402P-RELATED animal gross anatomical part developmental process#GO:0160108;embryonic organ development#GO:0048568;developmental process#GO:0032502;animal organ development#GO:0048513;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;cell migration#GO:0016477;cell motility#GO:0048870;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;embryo development#GO:0009790;cell development#GO:0048468;hemopoiesis#GO:0030097 IXOSC|EnsemblGenome=LOC115313921|UniProtKB=A0ACM8EX54 A0ACM8EX54 LOC115313921 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;steroid hydroxylase activity#GO:0008395;catalytic activity#GO:0003824 oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053017|UniProtKB=A0ACM8DR87 A0ACM8DR87 LOC8053017 PTHR39490:SF8 ARRESTIN DOMAIN-CONTAINING PROTEIN D ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 21 IXOSC|EnsemblGenome=LOC115314622|UniProtKB=A0ACM8DUF9 A0ACM8DUF9 LOC115314622 PTHR45080:SF41 CONTACTIN 5 PALLADIN molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023;transmembrane signaling receptor activity#GO:0004888 cellular component organization#GO:0016043;cellular process#GO:0009987;synapse organization#GO:0050808;cell junction organization#GO:0034330;cellular component organization or biogenesis#GO:0071840 plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;cell body#GO:0044297;neuron projection#GO:0043005;axon#GO:0030424 IXOSC|EnsemblGenome=LOC120847518|UniProtKB=A0ACM8FIR2 A0ACM8FIR2 LOC120847518 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115327111|UniProtKB=A0ACM8E7M2 A0ACM8E7M2 PTHR14604:SF4 WD40 REPEAT PF20 BETA-TRCP-LIKE ISOFORM X1 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;cullin-RING ubiquitin ligase complex#GO:0031461;SCF ubiquitin ligase complex#GO:0019005;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991 microtubule or microtubule-binding cytoskeletal protein#PC00157 Hedgehog signaling pathway#P00025>Slimb#P00683;Wnt signaling pathway#P00057>betaTrCP#P01454 IXOSC|EnsemblGenome=LOC115321278|UniProtKB=A0ACM8FBS3 A0ACM8FBS3 LOC115321278 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC120843374|UniProtKB=A0ACM8EVZ5 A0ACM8EVZ5 LOC120843374 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8052031|UniProtKB=A0ACM8F691 A0ACM8F691 LOC8052031 PTHR22603:SF36 CHOLINE/ETHANOALAMINE KINASE CHOLINE KINASE ALPHA kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773 phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;organophosphate biosynthetic process#GO:0090407;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;phosphatidylcholine metabolic process#GO:0046470;phosphatidylcholine biosynthetic process#GO:0006656;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 kinase#PC00137 IXOSC|EnsemblGenome=LOC8051097|UniProtKB=A0ACM8F6M6 A0ACM8F6M6 LOC8051097 PTHR15284:SF0 NUCLEAR FACTOR INTERLEUKIN-3-REGULATED PROTEIN GH23983P regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;circadian rhythm#GO:0007623;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;rhythmic process#GO:0048511;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;basic leucine zipper transcription factor#PC00056 IXOSC|EnsemblGenome=LOC8040933|UniProtKB=A0ACM8EWP3 A0ACM8EWP3 LOC8040933 PTHR10869:SF251 PROLYL 4-HYDROXYLASE ALPHA SUBUNIT PROLYL 4-HYDROXYLASE N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;oxidoreductase activity#GO:0016491;catalytic activity, acting on a protein#GO:0140096 intracellular anatomical structure#GO:0005622;endoplasmic reticulum protein-containing complex#GO:0140534;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;organelle#GO:0043226;oxidoreductase complex#GO:1990204 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC121047999|UniProtKB=A0ACM8FHC8 A0ACM8FHC8 LOC121047999 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844938|UniProtKB=A0ACM8EZL0 A0ACM8EZL0 LOC120844938 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC120841784|UniProtKB=A0ACM8FPZ4 A0ACM8FPZ4 LOC120841784 PTHR18806:SF4 RBM25 PROTEIN RNA-BINDING PROTEIN 25 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 regulation of biosynthetic process#GO:0009889;regulation of mRNA metabolic process#GO:1903311;regulation of gene expression#GO:0010468;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of mRNA processing#GO:0050684;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of biological process#GO:0050789 IXOSC|EnsemblGenome=LOC8051244|UniProtKB=A0ACM8E5D8 A0ACM8E5D8 stau PTHR46054:SF3 MATERNAL EFFECT PROTEIN STAUFEN MATERNAL EFFECT PROTEIN STAUFEN double-stranded RNA binding#GO:0003725;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 intracellular protein localization#GO:0008104;microtubule-based process#GO:0007017;protein localization to synapse#GO:0035418;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular developmental process#GO:0048869;developmental process#GO:0032502;transport#GO:0006810;intracellular transport#GO:0046907;cytoskeleton-dependent intracellular transport#GO:0030705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule localization#GO:0033036;axo-dendritic transport#GO:0008088;multicellular organismal reproductive process#GO:0048609;localization#GO:0051179;cellular localization#GO:0051641;anatomical structure development#GO:0048856;microtubule-based transport#GO:0099111;sexual reproduction#GO:0019953;protein localization to cell junction#GO:1902414;reproductive process#GO:0022414;cellular process involved in reproduction in multicellular organism#GO:0022412;cell development#GO:0048468;cell differentiation#GO:0030154;gamete generation#GO:0007276;microtubule-based movement#GO:0007018;RNA localization#GO:0006403;germ cell development#GO:0007281;developmental process involved in reproduction#GO:0003006 cell periphery#GO:0071944;neuron projection#GO:0043005;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cytoplasmic stress granule#GO:0010494;membraneless organelle#GO:0043228;cell body#GO:0044297;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;neuronal cell body#GO:0043025;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120836205|UniProtKB=A0ACM8FX06 A0ACM8FX06 LOC120836205 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8024849|UniProtKB=A0ACM8DMJ7 A0ACM8DMJ7 LOC8024849 PTHR10783:SF141 XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED SOLUTE CARRIER FAMILY 53 MEMBER 1 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;efflux transmembrane transporter activity#GO:0015562;active transmembrane transporter activity#GO:0022804 intracellular chemical homeostasis#GO:0055082;inorganic anion transport#GO:0015698;cellular homeostasis#GO:0019725;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;inorganic ion homeostasis#GO:0098771;transport#GO:0006810;chemical homeostasis#GO:0048878;homeostatic process#GO:0042592;export from cell#GO:0140352;phosphate ion transport#GO:0006817;cellular process#GO:0009987 plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8032161|UniProtKB=A0ACM8DQY7 A0ACM8DQY7 LOC8032161 PTHR43245:SF51 BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA HYDROXY-DELTA-5-STEROID DEHYDROGENASE, 3 BETA- AND STEROID DELTA-ISOMERASE 1 IXOSC|EnsemblGenome=LOC121837917|UniProtKB=A0ACM8G5P9 A0ACM8G5P9 LOC121837917 PTHR10514:SF27 ANGIOTENSIN-CONVERTING ENZYME ANGIOTENSIN-CONVERTING ENZYME-RELATED membrane#GO:0016020;extracellular region#GO:0005576;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8026399|UniProtKB=A0ACM8DS27 A0ACM8DS27 Nup54 PTHR13000:SF0 NUCLEOPORIN P54 NUCLEOPORIN P54 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 cellular component organization or biogenesis#GO:0071840;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;nucleus organization#GO:0006997;intracellular protein localization#GO:0008104;protein-containing complex organization#GO:0043933;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;organelle organization#GO:0006996;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;nuclear pore organization#GO:0006999;nuclear transport#GO:0051169;protein import into nucleus#GO:0006606;protein transport#GO:0015031;localization within membrane#GO:0051668;nucleocytoplasmic transport#GO:0006913;protein localization to organelle#GO:0033365;protein localization to membrane#GO:0072657;cellular component organization#GO:0016043 organelle envelope#GO:0031967;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;nuclear pore#GO:0005643;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC8024022|UniProtKB=A0ACM8EL46 A0ACM8EL46 PTHR11829:SF204 FORKHEAD BOX PROTEIN FORKHEAD BOX PROTEIN L1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 developmental process#GO:0032502;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;winged helix/forkhead transcription factor#PC00246;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8050989|UniProtKB=A0ACM8DLL6 A0ACM8DLL6 LOC8050989 PTHR13976:SF88 HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN-RELATED FI22004P1 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA splicing#GO:0043484;biological regulation#GO:0065007;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231 RNA splicing factor#PC00148;RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8037439|UniProtKB=A0ACM8EJL9 A0ACM8EJL9 LOC8037439 PTHR12786:SF2 SPLICING FACTOR SF3A-RELATED SPLICING FACTOR 3A SUBUNIT 3 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;snoRNA binding#GO:0030515 nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA biosynthetic process#GO:0032774;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375 small nuclear ribonucleoprotein complex#GO:0030532;spliceosomal complex#GO:0005681;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;U2 snRNP#GO:0005686;intracellular organelle#GO:0043229;spliceosomal snRNP complex#GO:0097525;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC121048365|UniProtKB=A0ACM8FHZ9 A0ACM8FHZ9 LOC121048365 PTHR48525:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310931|UniProtKB=A0ACM8F7G0 A0ACM8F7G0 LOC115310931 PTHR11610:SF200 LIPASE FI22312P1 catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120844414|UniProtKB=A0ACM8EYP0 A0ACM8EYP0 LOC120844414 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC120844255|UniProtKB=A0ACM8FYI9 A0ACM8FYI9 pHCl-1 PTHR18945:SF819 NEUROTRANSMITTER GATED ION CHANNEL PH-SENSITIVE CHLORIDE CHANNEL 1, ISOFORM N ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;excitatory extracellular ligand-gated monoatomic ion channel activity#GO:0005231;monoatomic ion channel activity#GO:0005216;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267 monoatomic anion transport#GO:0006820;cellular process#GO:0009987;monoatomic anion transmembrane transport#GO:0098656;monoatomic ion transmembrane transport#GO:0034220;chloride transport#GO:0006821;transport#GO:0006810;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;chloride transmembrane transport#GO:1902476;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic anion transport#GO:0015698 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ligand-gated ion channel#PC00141 IXOSC|EnsemblGenome=LOC115314018|UniProtKB=A0ACM8F3N7 A0ACM8F3N7 LOC115314018 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120846682|UniProtKB=A0ACM8FG66 A0ACM8FG66 LOC120846682 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028950|UniProtKB=A0ACM8DWN9 A0ACM8DWN9 LOC8028950 PTHR47385:SF27 CALPONIN MUSCLE-SPECIFIC PROTEIN 20 binding#GO:0005488;actin filament binding#GO:0051015;actin binding#GO:0003779;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;actin cytoskeleton#GO:0015629 IXOSC|EnsemblGenome=LOC8051063|UniProtKB=A0ACM8DNZ7 A0ACM8DNZ7 LOC8051063 PTHR24031:SF2 RNA HELICASE ATP-DEPENDENT RNA HELICASE DDX55 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8025694|UniProtKB=A0ACM8DJG1 A0ACM8DJG1 LOC8025694 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC8023194|UniProtKB=A0ACM8DQE2 A0ACM8DQE2 LOC8023194 PTHR24169:SF28 NUCLEAR FACTOR NF-KAPPA-B PROTEIN DORSAL-RELATED IMMUNITY FACTOR DIF-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 signaling#GO:0023052;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;intracellular signaling cassette#GO:0141124;positive regulation of macromolecule metabolic process#GO:0010604;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;regulation of nucleobase-containing compound metabolic process#GO:0019219;canonical NF-kappaB signal transduction#GO:0007249;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;Rel homology transcription factor#PC00252;gene-specific transcriptional regulator#PC00264 Toll pathway-drosophila#P06217>DL#P06344;Toll receptor signaling pathway#P00054>NFkappaB#P01354 IXOSC|EnsemblGenome=LOC8025964|UniProtKB=A0ACM8ELT5 A0ACM8ELT5 LOC8025964 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058;cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;microbody#GO:0042579 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121835306|UniProtKB=A0ACM8FTS5 A0ACM8FTS5 LOC121835306 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN circulatory system development#GO:0072359;heart development#GO:0007507;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856;system development#GO:0048731;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;post-embryonic development#GO:0009791;developmental process#GO:0032502 cellular anatomical structure#GO:0110165;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC8040408|UniProtKB=A0ACM8DQS6 A0ACM8DQS6 LOC8040408 PTHR31108:SF1 TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN TUMOR PROTEIN P63-REGULATED GENE 1-LIKE PROTEIN ISOFORM X1 IXOSC|EnsemblGenome=LOC8025681|UniProtKB=A0ACM8E4Q9 A0ACM8E4Q9 LOC8025681 PTHR10997:SF9 IMPORTIN-7, 8, 11 IMPORTIN-9 nucleocytoplasmic carrier activity#GO:0140142;molecular carrier activity#GO:0140104 protein localization to organelle#GO:0033365;cellular localization#GO:0051641;localization#GO:0051179;protein import into nucleus#GO:0006606;protein transport#GO:0015031;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810 nucleus#GO:0005634;cytosol#GO:0005829;organelle envelope#GO:0031967;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC120847812|UniProtKB=A0ACM8F4W5 A0ACM8F4W5 LOC121835689 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8050772|UniProtKB=A0ACM8E6K9 A0ACM8E6K9 LOC8050772 PTHR24255:SF31 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED CUB DOMAIN-CONTAINING PROTEIN serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120841017|UniProtKB=A0ACM8FV22 A0ACM8FV22 LOC120841017 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8036647|UniProtKB=A0ACM8DJX9 A0ACM8DJX9 LOC8036647 PTHR11351:SF104 ACYL-COA DESATURASE DESATURASE 1, ISOFORM A-RELATED catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;iron ion binding#GO:0005506;oxidoreductase activity#GO:0016491;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914;metal ion binding#GO:0046872;cation binding#GO:0043169 small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;unsaturated fatty acid biosynthetic process#GO:0006636;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987;monocarboxylic acid biosynthetic process#GO:0072330;unsaturated fatty acid metabolic process#GO:0033559;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum membrane#GO:0005789 IXOSC|EnsemblGenome=LOC120840707|UniProtKB=A0ACM8EQT4 A0ACM8EQT4 LOC120840707 PTHR21148:SF11 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 THIOREDOXIN DOMAIN-CONTAINING PROTEIN 9 cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC8050959|UniProtKB=A0ACM8DM60 A0ACM8DM60 LOC8050959 PTHR23140:SF0 RNA PROCESSING PROTEIN LD23810P U2 SNRNP-ASSOCIATED SURP MOTIF-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120848455|UniProtKB=A0ACM8F5N9 A0ACM8F5N9 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8039086|UniProtKB=A0ACM8G026 A0ACM8G026 LOC8039086 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8034179|UniProtKB=A0ACM8G893 A0ACM8G893 LOC8034179 PTHR23316:SF28 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;protein transport#GO:0015031;protein import into nucleus#GO:0006606;nuclear transport#GO:0051169;cellular localization#GO:0051641;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;protein localization to organelle#GO:0033365;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein localization to nucleus#GO:0034504;import into nucleus#GO:0051170;macromolecule localization#GO:0033036 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC8030229|UniProtKB=A0ACM8DGH1 A0ACM8DGH1 xit PTHR12413:SF2 DOLICHYL GLYCOSYLTRANSFERASE DOLICHYL PYROPHOSPHATE GLC1MAN9GLCNAC2 ALPHA-1,3-GLUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758 biosynthetic process#GO:0009058;glycoprotein biosynthetic process#GO:0009101;protein N-linked glycosylation#GO:0006487;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 metabolite interconversion enzyme#PC00262;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8038191|UniProtKB=A0ACM8DU49 A0ACM8DU49 LOC8038191 PTHR21024:SF0 GROWTH HORMONE-INDUCIBLE SOLUBLE PROTEIN-RELATED ELECTRON TRANSFER FLAVOPROTEIN REGULATORY FACTOR 1 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;negative regulation of cellular process#GO:0048523;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC120839314|UniProtKB=A0ACM8ELV8 A0ACM8ELV8 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121834688|UniProtKB=A0ACM8FQP6 A0ACM8FQP6 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843169|UniProtKB=A0ACM8FJM9 A0ACM8FJM9 LOC120843169 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050522|UniProtKB=A0ACM8DTW8 A0ACM8DTW8 LOC8050522 PTHR11929:SF145 ALPHA- 1,3 -FUCOSYLTRANSFERASE GLYCOPROTEIN 3-ALPHA-L-FUCOSYLTRANSFERASE A catalytic activity#GO:0003824;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115326006|UniProtKB=A0ACM8F5W3 A0ACM8F5W3 LOC115326006 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8029548|UniProtKB=A0ACM8F1C8 A0ACM8F1C8 LOC8029548 PTHR47333:SF8 VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN FIBULIN-5 IXOSC|EnsemblGenome=LOC115322928|UniProtKB=A0ACM8F9E2 A0ACM8F9E2 LOC115322928 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC115316580|UniProtKB=A0ACM8EV31 A0ACM8EV31 LOC115316580 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC120838913|UniProtKB=A0ACM8EK93 A0ACM8EK93 LOC120838913 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8032710|UniProtKB=A0ACM8DSQ5 A0ACM8DSQ5 LOC8032710 PTHR46415:SF2 ADAPTOR PROTEIN, PHOSPHOTYROSINE INTERACTION, PH DOMAIN AND LEUCINE ZIPPER-CONTAINING 2 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120841356|UniProtKB=A0ACM8ERH1 A0ACM8ERH1 LOC120841356 PTHR11533:SF306 PROTEASE M1 ZINC METALLOPROTEASE AMINOPEPTIDASE-RELATED peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;aminopeptidase activity#GO:0004177;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;metalloaminopeptidase activity#GO:0070006;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 catabolic process#GO:0009056;regulation of hormone levels#GO:0010817;primary metabolic process#GO:0044238;peptide metabolic process#GO:0006518;regulation of biological quality#GO:0065008;signaling receptor ligand precursor processing#GO:0140448;protein metabolic process#GO:0019538;proteolysis#GO:0006508;circulatory system process#GO:0003013;biosynthetic process#GO:0009058;biological regulation#GO:0065007;hormone metabolic process#GO:0042445;blood circulation#GO:0008015;protein maturation#GO:0051604;multicellular organismal process#GO:0032501;gene expression#GO:0010467;peptide catabolic process#GO:0043171;macromolecule biosynthetic process#GO:0009059;peptide hormone processing#GO:0016486;protein processing#GO:0016485;cellular process#GO:0009987;regulation of blood pressure#GO:0008217;regulation of systemic arterial blood pressure#GO:0003073;system process#GO:0003008;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8029415|UniProtKB=A0ACM8DPG2 A0ACM8DPG2 LOC8029415 PTHR19862:SF14 WD REPEAT-CONTAINING PROTEIN 48 WD REPEAT-CONTAINING PROTEIN 48 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;double-strand break repair#GO:0006302;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;recombinational repair#GO:0000725;cellular response to stress#GO:0033554;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular response to stimulus#GO:0051716;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896 IXOSC|EnsemblGenome=LOC121047139|UniProtKB=A0ACM8FGF9 A0ACM8FGF9 LOC121048546 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121837188|UniProtKB=A0ACM8G2Q4 A0ACM8G2Q4 LOC121837188 PTHR43948:SF10 DNAJ HOMOLOG SUBFAMILY B MRJ, ISOFORM E protein binding#GO:0005515;binding#GO:0005488;protein-folding chaperone binding#GO:0051087 biosynthetic process#GO:0009058;protein folding#GO:0006457;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8052859|UniProtKB=A0ACM8EHX4 A0ACM8EHX4 LOC8052859 PTHR43313:SF1 SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY 9C RETINOL DEHYDROGENASE 7 oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115323642|UniProtKB=A0ACM8G8D2 A0ACM8G8D2 LOC115323642 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8037687|UniProtKB=A0ACM8EVJ7 A0ACM8EVJ7 LOC8037687 PTHR19303:SF57 TRANSPOSON POGO TRANSPOSABLE ELEMENT WITH KRAB DOMAIN binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121045734|UniProtKB=A0ACM8FAU3 A0ACM8FAU3 LOC121045734 PTHR22930:SF302 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC121048036|UniProtKB=A0ACM8FHG4 A0ACM8FHG4 LOC121048036 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8037324|UniProtKB=A0ACM8DK43 A0ACM8DK43 LOC8037324 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8037671|UniProtKB=A0ACM8DI83 A0ACM8DI83 LOC8037671 PTHR13628:SF1 TRANSMEMBRANE PROTEIN 267 TRANSMEMBRANE PROTEIN 267 IXOSC|EnsemblGenome=LOC115325213|UniProtKB=A0ACM8E4N3 A0ACM8E4N3 LOC115325213 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC120848297|UniProtKB=A0ACM8F5T3 A0ACM8F5T3 LOC120848297 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115326052|UniProtKB=A0ACM8E6U5 A0ACM8E6U5 LOC115326052 PTHR20955:SF1 PROTEIN JAGUNAL HOMOLOG 1 PROTEIN JAGUNAL cellular process#GO:0009987;endoplasmic reticulum organization#GO:0007029;organelle organization#GO:0006996;cellular component organization#GO:0016043;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;transport#GO:0006810;localization#GO:0051179;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234 membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8026197|UniProtKB=A0ACM8G1P7 A0ACM8G1P7 LOC8026197 PTHR45954:SF1 LD33695P LD33695P molecular function regulator activity#GO:0098772;protein binding#GO:0005515;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;binding#GO:0005488 establishment or maintenance of cell polarity#GO:0007163;organelle localization#GO:0051640;localization#GO:0051179;spindle localization#GO:0051653;microtubule cytoskeleton organization#GO:0000226;cellular localization#GO:0051641;establishment of cell polarity#GO:0030010;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;mitotic cell cycle#GO:0000278;establishment of organelle localization#GO:0051656;mitotic cell cycle process#GO:1903047;establishment of spindle orientation#GO:0051294;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;establishment of mitotic spindle orientation#GO:0000132;establishment of spindle localization#GO:0051293;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;organelle organization#GO:0006996;establishment of mitotic spindle localization#GO:0040001;cytoskeleton organization#GO:0007010 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell cortex#GO:0005938;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC8033357|UniProtKB=A0ACM8EI77 A0ACM8EI77 LOC8033357 PTHR23235:SF130 KRUEPPEL-LIKE TRANSCRIPTION FACTOR ZINC FINGER PROTEIN 367 sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115315293|UniProtKB=A0ACM8DV64 A0ACM8DV64 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837917|UniProtKB=A0ACM8EJB6 A0ACM8EJB6 LOC120837917 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8051884|UniProtKB=A0ACM8EAL1 A0ACM8EAL1 LOC8051884 PTHR24067:SF394 UBIQUITIN-CONJUGATING ENZYME E2 E2 UBIQUITIN-CONJUGATING ENZYME cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491;Parkinson disease#P00049>UbcH7#P01224 IXOSC|EnsemblGenome=LOC8050742|UniProtKB=A0ACM8E4B1 A0ACM8E4B1 Unc50 PTHR12841:SF6 PROTEIN UNC-50 HOMOLOG PROTEIN UNC-50 HOMOLOG organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120846053|UniProtKB=A0ACM8F292 A0ACM8F292 LOC120846053 PTHR12000:SF57 HEMOGLOBINASE FAMILY MEMBER LEGUMAIN endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;cysteine-type peptidase activity#GO:0008234 protein catabolic process#GO:0030163;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;catabolic process#GO:0009056;gene expression#GO:0010467;protein maturation#GO:0051604 lysosome#GO:0005764;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323 protease#PC00190;cysteine protease#PC00081;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC120850811|UniProtKB=A0ACM8FBT5 A0ACM8FBT5 LOC120850811 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028067|UniProtKB=A0ACM8DP65 A0ACM8DP65 LOC8028067 PTHR46275:SF1 HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE protein binding#GO:0005515;binding#GO:0005488;ubiquitin binding#GO:0043130 endocytic recycling#GO:0032456;endocytosis#GO:0006897;localization#GO:0051179;cellular localization#GO:0051641;localization within membrane#GO:0051668;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;receptor internalization#GO:0031623;endosomal transport#GO:0016197;receptor-mediated endocytosis#GO:0006898;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;import into cell#GO:0098657;transport#GO:0006810;intracellular transport#GO:0046907 endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115314687|UniProtKB=A0ACM8DUK8 A0ACM8DUK8 LOC115314687 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8032364|UniProtKB=A0ACM8EHQ9 A0ACM8EHQ9 LOC8032364 PTHR23282:SF101 APICAL ENDOSOMAL GLYCOPROTEIN PRECURSOR. RT07201P-RELATED IXOSC|EnsemblGenome=LOC115319420|UniProtKB=A0ACM8F8H6 A0ACM8F8H6 LOC120849857 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038038|UniProtKB=A0ACM8E5B9 A0ACM8E5B9 alc PTHR10343:SF84 5'-AMP-ACTIVATED PROTEIN KINASE , BETA SUBUNIT 5'-AMP-ACTIVATED PROTEIN KINASE SUBUNIT BETA-1 protein binding#GO:0005515;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;kinase binding#GO:0019900;binding#GO:0005488 signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cell communication#GO:0007154 nucleus#GO:0005634;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;protein kinase complex#GO:1902911;intracellular protein-containing complex#GO:0140535 kinase modulator#PC00140;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120839939|UniProtKB=A0ACM8EMF5 A0ACM8EMF5 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8039604|UniProtKB=A0ACM8DKE6 A0ACM8DKE6 uri PTHR15111:SF2 RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3 UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1 molecular function regulator activity#GO:0098772;phosphatase inhibitor activity#GO:0019212;phosphatase regulator activity#GO:0019208;enzyme inhibitor activity#GO:0004857;transcription corepressor activity#GO:0003714;transcription coregulator activity#GO:0003712;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234;chromatin binding#GO:0003682;transcription regulator activity#GO:0140110;binding#GO:0005488 negative regulation of signal transduction#GO:0009968;negative regulation of programmed cell death#GO:0043069;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;negative regulation of intrinsic apoptotic signaling pathway#GO:2001243;regulation of apoptotic process#GO:0042981;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of programmed cell death#GO:0043067;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of DNA-templated transcription#GO:0045892;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of RNA biosynthetic process#GO:2001141;regulation of signal transduction#GO:0009966;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585;negative regulation of apoptotic process#GO:0043066;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of intrinsic apoptotic signaling pathway#GO:2001242;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;regulation of apoptotic signaling pathway#GO:2001233;negative regulation of apoptotic signaling pathway#GO:2001234 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115330921|UniProtKB=A0ACM8EZU3 A0ACM8EZU3 LOC115330921 PTHR11544:SF148 COLD SHOCK DOMAIN CONTAINING PROTEINS LD37574P nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8039180|UniProtKB=A0ACM8FMY8 A0ACM8FMY8 LOC8039180 PTHR38487:SF1 TESTIS EXPRESSED 11 PROTEIN ZIP4 HOMOLOG IXOSC|EnsemblGenome=LOC8051838|UniProtKB=A0ACM8DX43 A0ACM8DX43 LOC8051838 PTHR15114:SF1 REPLICATION PROTEIN A3 REPLICATION PROTEIN A 14 KDA SUBUNIT DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676;damaged DNA binding#GO:0003684;single-stranded DNA binding#GO:0003697 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;response to stimulus#GO:0050896;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;double-strand break repair via homologous recombination#GO:0000724;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;base-excision repair#GO:0006284;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA recombination#GO:0006310;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;response to stress#GO:0006950 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;protein-DNA complex#GO:0032993;replication fork#GO:0005657;replisome#GO:0030894;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;site of double-strand break#GO:0035861;membrane-enclosed lumen#GO:0031974;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 Cell cycle#P00013>Pre-replication Complex#P00478 IXOSC|EnsemblGenome=LOC121835326|UniProtKB=A0ACM8FUE8 A0ACM8FUE8 Hsdl2 PTHR42808:SF3 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 HYDROXYSTEROID DEHYDROGENASE-LIKE PROTEIN 2 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8042242|UniProtKB=A0ACM8FU42 A0ACM8FU42 LOC8042242 PTHR33444:SF7 SI:DKEY-19B23.12-RELATED TRANSMEMBRANE PROTEIN 272 IXOSC|EnsemblGenome=LOC8034427|UniProtKB=A0ACM8FN31 A0ACM8FN31 LOC8034427 PTHR44267:SF1 WD REPEAT-CONTAINING PROTEIN 43 WD REPEAT-CONTAINING PROTEIN 43 ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;RNA biosynthetic process#GO:0032774;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;ribosomal small subunit biogenesis#GO:0042274;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730 IXOSC|EnsemblGenome=LOC8034687|UniProtKB=A0ACM8DXD4 A0ACM8DXD4 Cadps PTHR12166:SF8 CALCIUM-DEPENDENT SECRETION ACTIVATOR CALCIUM-DEPENDENT SECRETION ACTIVATOR vesicle-mediated transport#GO:0016192;export from cell#GO:0140352;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;secretion#GO:0046903;secretion by cell#GO:0032940;exocytosis#GO:0006887;transport#GO:0006810 membrane traffic protein#PC00150;membrane trafficking regulatory protein#PC00151 IXOSC|EnsemblGenome=LOC8051506|UniProtKB=A0ACM8FRP8 A0ACM8FRP8 LOC8051506 PTHR42908:SF3 TRANSLATION ELONGATION FACTOR-RELATED ELONGATION FACTOR-LIKE GTPASE 1 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;GTPase activity#GO:0003924;protein-containing complex binding#GO:0044877;ribosome binding#GO:0043022;ribonucleoprotein complex binding#GO:0043021;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;translation factor activity#GO:0180051;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;translation elongation factor activity#GO:0003746 translation#GO:0006412;ribosome biogenesis#GO:0042254;organelle assembly#GO:0070925;ribosome assembly#GO:0042255;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;ribonucleoprotein complex biogenesis#GO:0022613;protein biosynthetic process#GO:0160307;translational elongation#GO:0006414;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;biosynthetic process#GO:0009058;gene expression#GO:0010467;cellular component assembly#GO:0022607 ribonucleoprotein complex#GO:1990904;cytosol#GO:0005829;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 translation elongation factor#PC00222 IXOSC|EnsemblGenome=LOC120841006|UniProtKB=A0ACM8ERR1 A0ACM8ERR1 LOC120841006 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121836059|UniProtKB=A0ACM8FWE4 A0ACM8FWE4 LOC121836059 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039537|UniProtKB=A0ACM8E319 A0ACM8E319 LOC8039537 PTHR45624:SF4 MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED CONGESTED-LIKE TRACHEA PROTEIN-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;quaternary ammonium group transmembrane transporter activity#GO:0015651 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;quaternary ammonium group transport#GO:0015697;nitrogen compound transport#GO:0071705;mitochondrial transport#GO:0006839;transport#GO:0006810;intracellular transport#GO:0046907;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;mitochondrion#GO:0005739;mitochondrial envelope#GO:0005740;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC120842838|UniProtKB=A0ACM8EUR6 A0ACM8EUR6 LOC120842838 PTHR24241:SF117 NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDE S RECEPTOR-LIKE transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;cell communication#GO:0007154;cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8051987|UniProtKB=A0ACM8DLJ6 A0ACM8DLJ6 LOC8051987 PTHR21096:SF0 PROTEIN FAM136A TIM DOUBLE TWIN CX3C MOTIF PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120841599|UniProtKB=A0ACM8ET28 A0ACM8ET28 LOC120841599 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115320069|UniProtKB=A0ACM8DZZ1 A0ACM8DZZ1 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115332986|UniProtKB=A0ACM8EF74 A0ACM8EF74 LOC115332986 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 metabolic process#GO:0008152;DNA metabolic process#GO:0006259;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;organelle organization#GO:0006996;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC120848108|UniProtKB=A0ACM8F664 A0ACM8F664 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC121835623|UniProtKB=A0ACM8FV43 A0ACM8FV43 LOC121835623 PTHR24366:SF96 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS REDUCED OCELLI, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8036355|UniProtKB=A0ACM8DRR5 A0ACM8DRR5 LOC8036355 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115321900|UniProtKB=A0ACM8F4W0 A0ACM8F4W0 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8027275|UniProtKB=A0ACM8F913 A0ACM8F913 LOC8027275 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804 sodium ion transport#GO:0006814;transport#GO:0006810;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8042413|UniProtKB=A0ACM8DUK9 A0ACM8DUK9 AspRS-m PTHR22594:SF56 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARTATE--TRNA LIGASE, MITOCHONDRIAL catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8030340|UniProtKB=A0ACM8F2R0 A0ACM8F2R0 LOC8030340 PTHR11909:SF20 CASEIN KINASE-RELATED CASEIN KINASE I ISOFORM ALPHA protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity#GO:0003824;transferase activity#GO:0016740;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096 negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051;cell communication#GO:0007154;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of cell communication#GO:0010646;regulation of Wnt signaling pathway#GO:0030111;signaling#GO:0023052;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;signal transduction#GO:0007165;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Wnt signaling pathway#P00057>Casein Kinase 1#P01460;Parkinson disease#P00049>Casein kinase I#P01242;Hedgehog signaling pathway#P00025>Casein kinase I#P00681 IXOSC|EnsemblGenome=LOC8039112|UniProtKB=A0ACM8DQ80 A0ACM8DQ80 PTHR18934:SF136 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX35-RELATED RNA binding#GO:0003723;ATP-dependent activity#GO:0140657;nucleic acid binding#GO:0003676;binding#GO:0005488;isomerase activity#GO:0016853;helicase activity#GO:0004386;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634 RNA helicase#PC00032;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115325615|UniProtKB=A0ACM8E5R5 A0ACM8E5R5 LOC115325615 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8039503|UniProtKB=A0ACM8DNP8 A0ACM8DNP8 Brd7-9 PTHR22881:SF48 BROMODOMAIN CONTAINING PROTEIN BROMODOMAIN CONTAINING 7_9 chromatin-protein adaptor activity#GO:0140463;histone reader activity#GO:0140566;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115330465|UniProtKB=A0ACM8F634 A0ACM8F634 LOC115330465 PTHR23226:SF416 ZINC FINGER AND SCAN DOMAIN-CONTAINING CROL ALPHA-RELATED transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8042164|UniProtKB=A0ACM8G0N7 A0ACM8G0N7 LOC8042164 PTHR15822:SF4 TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN 5'-TYROSYL-DNA PHOSPHODIESTERASE catalytic activity, acting on DNA#GO:0140097;phosphoric diester hydrolase activity#GO:0008081;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488;single-stranded DNA binding#GO:0003697 double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;nucleobase-containing compound metabolic process#GO:0006139;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC8029064|UniProtKB=A0ACM8ECU9 A0ACM8ECU9 LOC8029064 PTHR11588:SF524 TUBULIN TUBULIN BETA CHAIN structural molecule activity#GO:0005198;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;structural constituent of cytoskeleton#GO:0005200;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 cytoskeleton organization#GO:0007010;mitotic cell cycle#GO:0000278;cellular process#GO:0009987;cellular component organization#GO:0016043;cell cycle#GO:0007049;organelle organization#GO:0006996;microtubule-based process#GO:0007017;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;microtubule#GO:0005874;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;organelle#GO:0043226 cytoskeletal protein#PC00085;tubulin#PC00228 Cytoskeletal regulation by Rho GTPase#P00016>tubulin#P00526;Huntington disease#P00029>Microtubule#P00780;Huntington disease#P00029>beta-Tubulin#P00790 IXOSC|EnsemblGenome=LOC121833637|UniProtKB=A0ACM8FLP6 A0ACM8FLP6 LOC121833637 PTHR43038:SF3 ATP-BINDING CASSETTE, SUB-FAMILY H, MEMBER 1 ABC TRANSPORTER G FAMILY MEMBER 23 ISOFORM X1 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068;transporter#PC00227;ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8034877|UniProtKB=A0ACM8DJN3 A0ACM8DJN3 Arfrp1 PTHR45909:SF1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 ADP-RIBOSYLATION FACTOR-RELATED PROTEIN 1 pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 protein localization to membrane#GO:0072657;protein localization to plasma membrane#GO:0072659;Golgi to plasma membrane transport#GO:0006893;protein localization to organelle#GO:0033365;Golgi to plasma membrane protein transport#GO:0043001;establishment of protein localization to plasma membrane#GO:0061951;localization within membrane#GO:0051668;localization#GO:0051179;cellular localization#GO:0051641;post-Golgi vesicle-mediated transport#GO:0006892;protein transport#GO:0015031;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;vesicle-mediated transport#GO:0016192;protein localization to cell periphery#GO:1990778;protein localization to Golgi apparatus#GO:0034067;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886;Golgi vesicle transport#GO:0048193;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120845310|UniProtKB=A0ACM8EZX5 A0ACM8EZX5 LOC120845310 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121834279|UniProtKB=A0ACM8FPF6 A0ACM8FPF6 PTHR22948:SF29 TUDOR DOMAIN CONTAINING PROTEIN TUDOR DOMAIN-CONTAINING PROTEIN 5 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115324859|UniProtKB=A0ACM8G662 A0ACM8G662 LOC115324859 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833618|UniProtKB=A0ACM8FM30 A0ACM8FM30 LOC121833618 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115333206|UniProtKB=A0ACM8FCB9 A0ACM8FCB9 LOC115333206 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028221|UniProtKB=A0ACM8DRX4 A0ACM8DRX4 PTHR14843:SF2 DEUBIQUITINATING PROTEIN VCIP135 DEUBIQUITINATING PROTEIN VCPIP1 hydrolase activity#GO:0016787;deubiquitinase activity#GO:0101005;ubiquitin-like protein peptidase activity#GO:0019783;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;cysteine-type peptidase activity#GO:0008234;cysteine-type deubiquitinase activity#GO:0004843;catalytic activity#GO:0003824 DNA damage response#GO:0006974;endoplasmic reticulum membrane organization#GO:0090158;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular component biogenesis#GO:0044085;response to stress#GO:0006950;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;nucleobase-containing compound metabolic process#GO:0006139;organelle membrane fusion#GO:0090174;cellular component assembly#GO:0022607;organelle fusion#GO:0048284;cellular response to stress#GO:0033554;Golgi organization#GO:0007030;cellular response to stimulus#GO:0051716;endoplasmic reticulum organization#GO:0007029;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stimulus#GO:0050896 protease#PC00190;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115325765|UniProtKB=A0ACM8EYW3 A0ACM8EYW3 LOC115325765 PTHR39069:SF11 ECDYSONE-INDUCIBLE GENE E1, ISOFORM A EB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023857|UniProtKB=A0ACM8DHM1 A0ACM8DHM1 Wwox PTHR24320:SF292 RETINOL DEHYDROGENASE WW DOMAIN-CONTAINING OXIDOREDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;catalytic activity#GO:0003824 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8024635|UniProtKB=A0ACM8DIH7 A0ACM8DIH7 LOC8024635 PTHR12258:SF5 JANUS-A/JANUS-B SEX-REGULATED PROTEIN JANUS-A-RELATED catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;phosphoprotein phosphatase activity#GO:0004721 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 IXOSC|EnsemblGenome=LOC8025457|UniProtKB=A0ACM8DWI4 A0ACM8DWI4 Nurf-38 PTHR10286:SF92 INORGANIC PYROPHOSPHATASE INORGANIC PYROPHOSPHATASE hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;pyrophosphatase activity#GO:0016462 phosphate-containing compound metabolic process#GO:0006796;cellular process#GO:0009987;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 pyrophosphatase#PC00196 IXOSC|EnsemblGenome=LOC120844847|UniProtKB=A0ACM8EZX1 A0ACM8EZX1 PTHR34839:SF1 CS DOMAIN-CONTAINING PROTEIN MYOSIN-9-LIKE IXOSC|EnsemblGenome=LOC120848272|UniProtKB=A0ACM8FKL7 A0ACM8FKL7 LOC120848272 PTHR13794:SF58 ENOLASE SUPERFAMILY, MANDELATE RACEMASE MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 epimerase/racemase#PC00096 IXOSC|EnsemblGenome=LOC8053497|UniProtKB=A0ACM8EI07 A0ACM8EI07 LOC8053497 PTHR11530:SF11 D-AMINO ACID OXIDASE D-AMINO ACID OXIDASE 2, ISOFORM A oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidase#PC00175 IXOSC|EnsemblGenome=LOC8038376|UniProtKB=A0ACM8E3T9 A0ACM8E3T9 LOC8038376 PTHR11451:SF46 THREONINE-TRNA LIGASE THREONINE--TRNA LIGASE catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098 tRNA aminoacylation#GO:0043039;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA aminoacylation for protein translation#GO:0006418;gene expression#GO:0010467;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;amino acid activation#GO:0043038;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538 aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC115310395|UniProtKB=A0ACM8FM02 A0ACM8FM02 LOC115310395 PTHR10642:SF35 RIBONUCLEASE H1 RIBONUCLEASE H1 RNA nuclease activity#GO:0004540;endonuclease activity#GO:0004519;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;DNA replication#GO:0006260;catabolic process#GO:0009056;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;mitochondrial DNA metabolic process#GO:0032042;DNA-templated DNA replication#GO:0006261;nucleobase-containing compound catabolic process#GO:0034655;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;nucleus#GO:0005634 endoribonuclease#PC00094;RNA metabolism protein#PC00031 DNA replication#P00017>RNase H#P00538 IXOSC|EnsemblGenome=LOC8027969|UniProtKB=A0ACM8E6B1 A0ACM8E6B1 LOC8027969 PTHR46355:SF1 UPF0428 PROTEIN CXORF56 STING ER EXIT PROTEIN vesicle-mediated transport#GO:0016192;endomembrane system organization#GO:0010256;membrane organization#GO:0061024;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular transport#GO:0046907;endoplasmic reticulum membrane organization#GO:0090158;transport#GO:0006810;Golgi vesicle transport#GO:0048193;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;localization#GO:0051179;cellular localization#GO:0051641;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 IXOSC|EnsemblGenome=LOC120835965|UniProtKB=A0ACM8FAA4 A0ACM8FAA4 LOC120835965 PTHR10454:SF254 CASPASE CELL DEATH PROTEIN 3 enzyme regulator activity#GO:0030234;hydrolase activity#GO:0016787;molecular function activator activity#GO:0140677;cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;enzyme activator activity#GO:0008047;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;cysteine-type endopeptidase activity#GO:0004197;molecular function regulator activity#GO:0098772 regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;positive regulation of neuron apoptotic process#GO:0043525;macromolecule metabolic process#GO:0043170;positive regulation of apoptotic process#GO:0043065;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;regulation of neuron apoptotic process#GO:0043523;biological regulation#GO:0065007;proteolysis#GO:0006508;protein metabolic process#GO:0019538;execution phase of apoptosis#GO:0097194;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;positive regulation of programmed cell death#GO:0043068;regulation of cellular process#GO:0050794 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC121836590|UniProtKB=A0ACM8G074 A0ACM8G074 LOC121836590 PTHR37984:SF32 PROTEIN CBG26694 RNA-DIRECTED DNA POLYMERASE IXOSC|EnsemblGenome=LOC8038880|UniProtKB=A0ACM8DNW4 A0ACM8DNW4 LOC8038880 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;lipase activity#GO:0016298;catalytic activity#GO:0003824 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;lipid metabolic process#GO:0006629;cellular process#GO:0009987;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 IXOSC|EnsemblGenome=LOC8025322|UniProtKB=A0ACM8EMN1 A0ACM8EMN1 LOC8025322 PTHR11920:SF515 GUANYLYL CYCLASE GUANYLATE CYCLASE molecular transducer activity#GO:0060089;lyase activity#GO:0016829;peptide receptor activity#GO:0001653;guanylate cyclase activity#GO:0004383;signaling receptor activity#GO:0038023;catalytic activity#GO:0003824;cyclase activity#GO:0009975;phosphorus-oxygen lyase activity#GO:0016849 nucleoside phosphate metabolic process#GO:0006753;regulation of cellular process#GO:0050794;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;enzyme-linked receptor protein signaling pathway#GO:0007167;organophosphate biosynthetic process#GO:0090407;cGMP biosynthetic process#GO:0006182;cell communication#GO:0007154;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cGMP metabolic process#GO:0046068;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637;ribonucleotide biosynthetic process#GO:0009260;nucleoside phosphate biosynthetic process#GO:1901293;cyclic nucleotide metabolic process#GO:0009187;signaling#GO:0023052;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;purine-containing compound metabolic process#GO:0072521;regulation of biological process#GO:0050789;purine nucleotide metabolic process#GO:0006163;phosphorus metabolic process#GO:0006793;nucleotide biosynthetic process#GO:0009165;purine ribonucleotide biosynthetic process#GO:0009152;nucleotide metabolic process#GO:0009117;cyclic nucleotide biosynthetic process#GO:0009190;ribonucleotide metabolic process#GO:0009259;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;signal transduction#GO:0007165;receptor guanylyl cyclase signaling pathway#GO:0007168;ribose phosphate biosynthetic process#GO:0046390;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative biosynthetic process#GO:1901137;cell surface receptor signaling pathway#GO:0007166;cyclic purine nucleotide metabolic process#GO:0052652;nucleobase-containing compound biosynthetic process#GO:0034654;purine ribonucleotide metabolic process#GO:0009150;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanylate cyclase#PC00114;lyase#PC00144 IXOSC|EnsemblGenome=LOC115319188|UniProtKB=A0ACM8FUE3 A0ACM8FUE3 LOC115319188 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8025665|UniProtKB=A0ACM8E9J8 A0ACM8E9J8 msps PTHR12609:SF0 MICROTUBULE ASSOCIATED PROTEIN XMAP215 CYTOSKELETON-ASSOCIATED PROTEIN 5 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;catalytic activity, acting on a protein#GO:0140096;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;microtubule polymerization or depolymerization#GO:0031109;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;spindle organization#GO:0007051;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;microtubule organizing center organization#GO:0031023;microtubule polymerization#GO:0046785;protein-containing complex organization#GO:0043933;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;mitotic cell cycle#GO:0000278;mitotic spindle organization#GO:0007052;cell cycle#GO:0007049;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;protein-containing complex assembly#GO:0065003;protein polymerization#GO:0051258;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;microtubule cytoskeleton organization#GO:0000226;supramolecular fiber organization#GO:0097435;establishment or maintenance of cell polarity#GO:0007163 intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;microtubule#GO:0005874;microtubule end#GO:1990752;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;microtubule organizing center#GO:0005815;centrosome#GO:0005813;spindle#GO:0005819;polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;microtubule plus-end#GO:0035371;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080 non-motor microtubule binding protein#PC00166 IXOSC|EnsemblGenome=LOC8039379|UniProtKB=A0ACM8FTP6 A0ACM8FTP6 LOC8039379 PTHR15228:SF37 SPERMATHECAL PHYSIOLOGY VARIANT F-BAR DOMAIN-CONTAINING PROTEIN enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695 regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of small GTPase mediated signal transduction#GO:0051056;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583 G-protein modulator#PC00022;protein-binding activity modulator#PC00095;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC8036257|UniProtKB=A0ACM8DHB1 A0ACM8DHB1 LOC8036257 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8050584|UniProtKB=A0ACM8DYI7 A0ACM8DYI7 LOC8050584 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8032629|UniProtKB=A0ACM8G7S3 A0ACM8G7S3 LOC8032629 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120848641|UniProtKB=A0ACM8F6G0 A0ACM8F6G0 LOC120848641 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;extracellular region#GO:0005576;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8033124|UniProtKB=A0ACM8DHG2 A0ACM8DHG2 Polr3H PTHR12709:SF1 DNA-DIRECTED RNA POLYMERASE II, III DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC8 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;DNA-templated transcription initiation#GO:0006352;transcription initiation at RNA polymerase III promoter#GO:0006384;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;transcription by RNA polymerase III#GO:0006383 membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase III complex#GO:0005666;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;protein-containing complex#GO:0032991;RNA polymerase complex#GO:0030880;nucleus#GO:0005634 DNA-directed RNA polymerase#PC00019;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115330245|UniProtKB=A0ACM8F974 A0ACM8F974 LOC115330245 PTHR11081:SF8 FLAP ENDONUCLEASE FAMILY MEMBER EXONUCLEASE 1 DNA nuclease activity#GO:0004536;hydrolase activity, acting on ester bonds#GO:0016788;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;nuclease activity#GO:0004518;hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520 DNA metabolism protein#PC00009;exodeoxyribonuclease#PC00098 IXOSC|EnsemblGenome=LOC8023216|UniProtKB=A0ACM8F9F1 A0ACM8F9F1 LOC8023216 PTHR11849:SF289 ETS ETS-LIKE PROTEIN POINTED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 winged helix/forkhead transcription factor#PC00246;DNA-binding transcription factor#PC00218 PDGF signaling pathway#P00047>Ets#P01167 IXOSC|EnsemblGenome=LOC120846794|UniProtKB=A0ACM8F3A5 A0ACM8F3A5 LOC120846794 PTHR23080:SF147 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115313137|UniProtKB=A0ACM8DSV2 A0ACM8DSV2 LOC115313137 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8040325|UniProtKB=A0ACM8E8X9 A0ACM8E8X9 LOC8040325 PTHR15204:SF0 LARGE PROLINE-RICH PROTEIN BAG6 LARGE PROLINE-RICH PROTEIN BAG6 polyubiquitin modification-dependent protein binding#GO:0031593;modification-dependent protein binding#GO:0140030;binding#GO:0005488;protein binding#GO:0005515 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;response to endoplasmic reticulum stress#GO:0034976;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;catabolic process#GO:0009056;response to stimulus#GO:0050896;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;proteasomal protein catabolic process#GO:0010498;response to chemical#GO:0042221 cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120839533|UniProtKB=A0ACM8EN44 A0ACM8EN44 LOC120839533 PTHR23316:SF71 IMPORTIN ALPHA IMPORTIN SUBUNIT ALPHA molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;protein transport#GO:0015031;protein import into nucleus#GO:0006606;NLS-bearing protein import into nucleus#GO:0006607;localization#GO:0051179;cellular localization#GO:0051641;protein localization to organelle#GO:0033365;intracellular protein transport#GO:0006886;transport#GO:0006810;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;import into nucleus#GO:0051170;macromolecule localization#GO:0033036;protein localization to nucleus#GO:0034504 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transporter#PC00227 IXOSC|EnsemblGenome=LOC8024717|UniProtKB=A0ACM8DIK6 A0ACM8DIK6 LOC8024717 PTHR11559:SF370 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE-RELATED esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 IXOSC|EnsemblGenome=LOC115311313|UniProtKB=A0ACM8FA46 A0ACM8FA46 rdgA PTHR11255:SF127 DIACYLGLYCEROL KINASE EYE-SPECIFIC DIACYLGLYCEROL KINASE transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, alcohol group as acceptor#GO:0016773;lipid kinase activity#GO:0001727 response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cell communication#GO:0007154;organophosphate biosynthetic process#GO:0090407;intracellular signal transduction#GO:0035556;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;biological regulation#GO:0065007;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;signal transduction#GO:0007165;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;neutral lipid metabolic process#GO:0006638;metabolic process#GO:0008152;acylglycerol metabolic process#GO:0006639;glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629 membrane#GO:0016020;cellular anatomical structure#GO:0110165 kinase#PC00137;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120848735|UniProtKB=A0ACM8FKC4 A0ACM8FKC4 LOC120848735 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC120838749|UniProtKB=A0ACM8EJV0 A0ACM8EJV0 LOC120838749 PTHR14710:SF2 GEM-ASSOCIATED PROTEIN 6 GEM-ASSOCIATED PROTEIN 6 protein-containing complex assembly#GO:0065003;mRNA splicing, via spliceosome#GO:0000398;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;spliceosomal snRNP assembly#GO:0000387;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;protein-RNA complex assembly#GO:0022618;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cellular component biogenesis#GO:0044085;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;cellular component assembly#GO:0022607;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;protein-containing complex organization#GO:0043933;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;protein-RNA complex organization#GO:0071826 SMN complex#GO:0032797;intracellular anatomical structure#GO:0005622;SMN-Sm protein complex#GO:0034719;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;Sm-like protein family complex#GO:0120114 IXOSC|EnsemblGenome=LOC121837494|UniProtKB=A0ACM8G4P4 A0ACM8G4P4 LOC121837494 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328990|UniProtKB=A0ACM8E9E5 A0ACM8E9E5 LOC115328990 PTHR48112:SF31 HIGH MOBILITY GROUP PROTEIN DSP1 HMG BOX DOMAIN-CONTAINING PROTEIN cellular component organization or biogenesis#GO:0071840;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;cellular component organization#GO:0016043;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 gene-specific transcriptional regulator#PC00264;HMG box transcription factor#PC00024 IXOSC|EnsemblGenome=LOC115323031|UniProtKB=A0ACM8F2F0 A0ACM8F2F0 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural molecule activity#GO:0005198;structural constituent of cytoskeleton#GO:0005200 negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component assembly#GO:0022607;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular localization#GO:0051641;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;establishment of organelle localization#GO:0051656;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;nucleus organization#GO:0006997;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;regulation of macromolecule biosynthetic process#GO:0010556;protein localization to nucleus#GO:0034504;regulation of metabolic process#GO:0019222;epigenetic regulation of gene expression#GO:0040029;macromolecule localization#GO:0033036;negative regulation of macromolecule metabolic process#GO:0010605;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;membrane organization#GO:0061024;chromatin organization#GO:0006325;organelle localization#GO:0051640;localization within membrane#GO:0051668;localization#GO:0051179;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;endomembrane system#GO:0012505;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;organelle envelope#GO:0031967;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC8038167|UniProtKB=A0ACM8DGN1 A0ACM8DGN1 RpL23A PTHR11620:SF2 60S RIBOSOMAL PROTEIN L23A LARGE RIBOSOMAL SUBUNIT PROTEIN UL23 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8052691|UniProtKB=A0ACM8FER7 A0ACM8FER7 PTHR23413:SF1 60S RIBOSOMAL PROTEIN L32 AND DNA-DIRECTED RNA POLYMERASE II, SUBUNIT N 60S RIBOSOMAL PROTEIN L32 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;cytosol#GO:0005829;ribosome#GO:0005840;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115332206|UniProtKB=A0ACM8EDZ3 A0ACM8EDZ3 mRpL50 PTHR31542:SF1 39A RIBOSOMAL PROTEIN L50, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN ML50 organelle lumen#GO:0043233;ribosome#GO:0005840;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;membrane-enclosed lumen#GO:0031974;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC115312498|UniProtKB=A0ACM8F333 A0ACM8F333 LOC115312498 PTHR10342:SF275 ARYLSULFATASE RE14504P catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 IXOSC|EnsemblGenome=LOC8034174|UniProtKB=A0ACM8FF60 A0ACM8FF60 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC115309697|UniProtKB=A0ACM8F054 A0ACM8F054 LOC115309697 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115324742|UniProtKB=A0ACM8ER58 A0ACM8ER58 LOC115324742 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120844218|UniProtKB=A0ACM8EXT9 A0ACM8EXT9 LOC120844218 PTHR46579:SF6 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025894|UniProtKB=A0ACM8DGN0 A0ACM8DGN0 LOC8025894 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE protein metabolic process#GO:0019538;protein refolding#GO:0042026;response to stimulus#GO:0050896;protein folding#GO:0006457;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;response to stress#GO:0006950;response to heat#GO:0009408;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC115316030|UniProtKB=A0ACM8DVH2 A0ACM8DVH2 LOC115316030 PTHR11010:SF128 PROTEASE S28 PRO-X CARBOXYPEPTIDASE-RELATED LYSOSOMAL PRO-X CARBOXYPEPTIDASE cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;lysosome#GO:0005764;lytic vacuole#GO:0000323;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 serine protease#PC00203 IXOSC|EnsemblGenome=LOC120840844|UniProtKB=A0ACM8EQE6 A0ACM8EQE6 LOC120840844 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120847938|UniProtKB=A0ACM8G7X5 A0ACM8G7X5 LOC120847938 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033695|UniProtKB=A0ACM8ESM6 A0ACM8ESM6 LOC8033695 PTHR23278:SF33 SIDESTEP PROTEIN SIDESTEP VIII, ISOFORM B immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC8027293|UniProtKB=A0ACM8DIW7 A0ACM8DIW7 LOC8027293 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity#GO:0016740;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 metabolic process#GO:0008152;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC115313546|UniProtKB=A0ACM8DSX1 A0ACM8DSX1 LOC115313546 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC121048502|UniProtKB=A0ACM8FJG7 A0ACM8FJG7 LOC121048502 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 catabolic process#GO:0009056;metabolic process#GO:0008152;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;extracellular region#GO:0005576;cell periphery#GO:0071944;membrane#GO:0016020 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC121838509|UniProtKB=A0ACM8G949 A0ACM8G949 LOC121838509 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121834008|UniProtKB=A0ACM8FMJ2 A0ACM8FMJ2 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120850046|UniProtKB=A0ACM8F9B5 A0ACM8F9B5 LOC120850046 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121046677|UniProtKB=A0ACM8FEQ9 A0ACM8FEQ9 LOC121046677 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848261|UniProtKB=A0ACM8F5F3 A0ACM8F5F3 LOC120848261 PTHR14950:SF82 DICER-RELATED ENDORIBONUCLEASE DICER hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;DNA endonuclease activity, producing 5'-phosphomonoesters#GO:0016888;catalytic activity, acting on a nucleic acid#GO:0140640;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;nucleic acid binding#GO:0003676;hydrolase activity#GO:0016787;RNA binding#GO:0003723;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521;catalytic activity, acting on DNA#GO:0140097;binding#GO:0005488;nuclease activity#GO:0004518;DNA endonuclease activity#GO:0004520 RNA metabolic process#GO:0016070;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;negative regulation of metabolic process#GO:0009892;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;siRNA processing#GO:0030422;apoptotic process#GO:0006915;regulation of biological process#GO:0050789;execution phase of apoptosis#GO:0097194;cellular component organization or biogenesis#GO:0071840;DNA metabolic process#GO:0006259;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;gene expression#GO:0010467;RNA processing#GO:0006396;apoptotic DNA fragmentation#GO:0006309;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;pre-miRNA processing#GO:0031054;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;programmed cell death#GO:0012501;cell death#GO:0008219;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;regulatory ncRNA processing#GO:0070918;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound catabolic process#GO:0034655;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;endoribonuclease complex#GO:1902555;endonuclease complex#GO:1905348;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8033901|UniProtKB=A0ACM8ER96 A0ACM8ER96 LOC8033901 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121835727|UniProtKB=A0ACM8FUV2 A0ACM8FUV2 LOC121835727 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC120837106|UniProtKB=A0ACM8EGM1 A0ACM8EGM1 LOC120837106 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330040|UniProtKB=A0ACM8FVK0 A0ACM8FVK0 LOC115330040 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115330940|UniProtKB=A0ACM8G5V4 A0ACM8G5V4 LOC115330940 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120840726|UniProtKB=A0ACM8EPD1 A0ACM8EPD1 LOC120840726 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033007|UniProtKB=A0ACM8EEB7 A0ACM8EEB7 BBS9 PTHR20991:SF0 PARATHYROID HORMONE-RESPONSIVE B1 GENE PROTEIN PTHB1 cellular process#GO:0009987;cell projection assembly#GO:0030031;cilium assembly#GO:0060271;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection organization#GO:0030030;plasma membrane bounded cell projection assembly#GO:0120031;organelle assembly#GO:0070925;cilium organization#GO:0044782;cellular component organization or biogenesis#GO:0071840 membrane#GO:0016020;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;BBSome#GO:0034464;cilium#GO:0005929;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC121836143|UniProtKB=A0ACM8FYI4 A0ACM8FYI4 LOC121836143 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115332988|UniProtKB=A0ACM8EVT3 A0ACM8EVT3 Stip1 PTHR22904:SF523 TPR REPEAT CONTAINING PROTEIN STRESS-INDUCED-PHOSPHOPROTEIN 1 protein binding#GO:0005515;binding#GO:0005488;heat shock protein binding#GO:0031072;Hsp90 protein binding#GO:0051879 IXOSC|EnsemblGenome=LOC8051087|UniProtKB=A0ACM8DLA9 A0ACM8DLA9 LOC8051087 PTHR12454:SF11 TRIMERIC INTRACELLULAR CATION CHANNEL GH25683P passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;metal ion transmembrane transporter activity#GO:0046873;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;monoatomic cation transmembrane transporter activity#GO:0008324 transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;cellular process#GO:0009987;potassium ion transport#GO:0006813;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220 membrane#GO:0016020;sarcoplasmic reticulum#GO:0016529;endomembrane system#GO:0012505;sarcoplasmic reticulum membrane#GO:0033017;cytoplasm#GO:0005737;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;sarcoplasm#GO:0016528;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC121046422|UniProtKB=A0ACM8FMX2 A0ACM8FMX2 LOC121046422 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115326744|UniProtKB=A0ACM8EPM2 A0ACM8EPM2 LOC115326744 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;organelle organization#GO:0006996;cellular process#GO:0009987 IXOSC|EnsemblGenome=LOC115321496|UniProtKB=A0ACM8F4K1 A0ACM8F4K1 LOC121836284 PTHR23430:SF50 HISTONE H2A HISTONE H2A structural molecule activity#GO:0005198 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;heterochromatin formation#GO:0031507;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;negative regulation of gene expression, epigenetic#GO:0045814;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;cellular component assembly#GO:0022607;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;biological regulation#GO:0065007;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleosome#GO:0000786;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;protein-DNA complex#GO:0032993;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;nucleus#GO:0005634;chromosome#GO:0005694 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8034051|UniProtKB=A0ACM8DZ28 A0ACM8DZ28 LOC8034051 PTHR14269:SF60 CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE-RELATED CARDIOLIPIN SYNTHASE (CMP-FORMING) transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phosphatidylglycerol biosynthetic process#GO:0006655;phospholipid metabolic process#GO:0006644;phospholipid biosynthetic process#GO:0008654;phosphatidylglycerol metabolic process#GO:0046471;glycerolipid metabolic process#GO:0046486;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;cellular process#GO:0009987;glycerolipid biosynthetic process#GO:0045017;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8039438|UniProtKB=A0ACM8DKD0 A0ACM8DKD0 LOC8039438 PTHR20930:SF2 OVARIAN CARCINOMA ANTIGEN CA125-RELATED NEXT TO BRCA1 GENE 1 PROTEIN protein transport#GO:0015031;process utilizing autophagic mechanism#GO:0061919;localization#GO:0051179;cellular localization#GO:0051641;protein localization to vacuole#GO:0072665;establishment of protein localization to vacuole#GO:0072666;catabolic process#GO:0009056;protein targeting#GO:0006605;protein localization to organelle#GO:0033365;intracellular protein localization#GO:0008104;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;intracellular protein transport#GO:0006886;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;macroautophagy#GO:0016236;establishment of localization in cell#GO:0051649;autophagy#GO:0006914;establishment of protein localization#GO:0045184;cellular process#GO:0009987;macromolecule localization#GO:0033036;protein targeting to vacuole#GO:0006623 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;autophagosome#GO:0005776;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC115327820|UniProtKB=A0ACM8EEY2 A0ACM8EEY2 LOC115327820 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121836452|UniProtKB=A0ACM8FYU1 A0ACM8FYU1 LOC121836452 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 sodium ion transport#GO:0006814;transport#GO:0006810;metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;establishment of localization#GO:0051234 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8027746|UniProtKB=A0ACM8DJB0 A0ACM8DJB0 LOC8027746 PTHR24107:SF2 YNEIN REGULATORY COMPLEX SUBUNIT 5 NLR FAMILY CARD DOMAIN CONTAINING 3 microtubule or microtubule-binding cytoskeletal protein#PC00157;non-motor microtubule binding protein#PC00166;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8028457|UniProtKB=A0ACM8E965 A0ACM8E965 Su(Tpl) PTHR23288:SF17 OCCLUDIN AND RNA POLYMERASE II ELONGATION FACTOR ELL RNA POLYMERASE II ELONGATION FACTOR ELL nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;RNA metabolic process#GO:0016070;regulation of transcription elongation by RNA polymerase II#GO:0034243;nucleic acid biosynthetic process#GO:0141187;regulation of DNA-templated transcription elongation#GO:0032784;snRNA transcription#GO:0009301;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;metabolic process#GO:0008152;positive regulation of transcription by RNA polymerase II#GO:0045944;nucleobase-containing compound biosynthetic process#GO:0034654;positive regulation of macromolecule metabolic process#GO:0010604;gene expression#GO:0010467;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of RNA metabolic process#GO:0051252;positive regulation of biosynthetic process#GO:0009891;snRNA metabolic process#GO:0016073;regulation of DNA-templated transcription#GO:0006355;RNA biosynthetic process#GO:0032774;DNA-templated transcription#GO:0006351;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;snRNA transcription by RNA polymerase II#GO:0042795;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;transcription by RNA polymerase II#GO:0006366;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;macromolecule biosynthetic process#GO:0009059;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;transcription elongation factor complex#GO:0008023;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleoplasm#GO:0005654 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC115319722|UniProtKB=A0ACM8FWF0 A0ACM8FWF0 LOC115319722 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC121837985|UniProtKB=A0ACM8G7E2 A0ACM8G7E2 LOC121837985 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120844817|UniProtKB=A0ACM8EZR5 A0ACM8EZR5 LOC120844817 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8040377|UniProtKB=A0ACM8EBC5 A0ACM8EBC5 LOC8040377 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC121837734|UniProtKB=A0ACM8G5Y5 A0ACM8G5Y5 LOC121837734 PTHR22589:SF115 CARNITINE O-ACYLTRANSFERASE CARNITINE O-ACETYL-TRANSFERASE, ISOFORM A-RELATED acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acetyltransferase activity#GO:0016407;catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746 cellular process#GO:0009987;carnitine metabolic process#GO:0009437;modified amino acid metabolic process#GO:0006575;metabolic process#GO:0008152 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;microbody#GO:0042579;peroxisome#GO:0005777;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 acyltransferase#PC00042;metabolite interconversion enzyme#PC00262 Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CAT#P01076;Nicotinic acetylcholine receptor signaling pathway#P00044>CAT#P01087;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CAT#P01063 IXOSC|EnsemblGenome=LOC115311730|UniProtKB=A0ACM8DR70 A0ACM8DR70 LOC115311730 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;enzyme regulator activity#GO:0030234;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207 G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle process#GO:1903047;cellular process#GO:0009987;cell cycle process#GO:0022402;cell cycle G1/S phase transition#GO:0044843;cell cycle#GO:0007049;cell cycle phase transition#GO:0044770;mitotic cell cycle#GO:0000278 nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;serine/threonine protein kinase complex#GO:1902554;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC8038940|UniProtKB=A0ACM8DK95 A0ACM8DK95 LOC8038940 PTHR16505:SF8 PROTEIN LZIC PROTEIN LZIC IXOSC|EnsemblGenome=LOC8054044|UniProtKB=A0ACM8DYG9 A0ACM8DYG9 LOC8054044 PTHR12129:SF15 HEPARAN SULFATE 2-O-SULFOTRANSFERASE URONYL 2-SULFOTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115317044|UniProtKB=A0ACM8DXA9 A0ACM8DXA9 LOC115317044 PTHR48536:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314819|UniProtKB=A0ACM8EII0 A0ACM8EII0 LOC115314819 PTHR10259:SF11 THIOPURINE S-METHYLTRANSFERASE THIOPURINE S-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757 methyltransferase#PC00155;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8036486|UniProtKB=A0ACM8DHH9 A0ACM8DHH9 LOC8036486 PTHR11241:SF0 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE metal ion binding#GO:0046872;hydrolase activity#GO:0016787;magnesium ion binding#GO:0000287;cation binding#GO:0043169;small molecule binding#GO:0036094;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;binding#GO:0005488;ion binding#GO:0043167;nucleoside triphosphate diphosphatase activity#GO:0047429;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817 organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165;nucleoside monophosphate biosynthetic process#GO:0009124;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;nucleoside monophosphate metabolic process#GO:0009123;nucleoside phosphate metabolic process#GO:0006753;carbohydrate derivative catabolic process#GO:1901136;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;nucleoside phosphate biosynthetic process#GO:1901293;carbohydrate derivative biosynthetic process#GO:1901137;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleotide catabolic process#GO:0009166;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;pyrimidine-containing compound metabolic process#GO:0072527;cellular process#GO:0009987 phosphatase#PC00181;hydrolase#PC00121 De novo pyrimidine deoxyribonucleotide biosynthesis#P02739>dUTP pyrophosphatase#P02918 IXOSC|EnsemblGenome=LOC121836057|UniProtKB=A0ACM8FWZ9 A0ACM8FWZ9 LOC121836057 PTHR12266:SF38 NA+/CA2+ K+ INDEPENDENT EXCHANGER GH07338P-RELATED active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;sodium ion transmembrane transporter activity#GO:0015081;monoatomic ion transmembrane transporter activity#GO:0015075;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;antiporter activity#GO:0015297;monoatomic cation transmembrane transporter activity#GO:0008324;calcium ion transmembrane transporter activity#GO:0015085 monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;inorganic ion homeostasis#GO:0098771;calcium ion homeostasis#GO:0055074;homeostatic process#GO:0042592;intracellular monoatomic ion homeostasis#GO:0006873;intracellular chemical homeostasis#GO:0055082;intracellular calcium ion homeostasis#GO:0006874;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic ion homeostasis#GO:0050801 cellular anatomical structure#GO:0110165;membrane#GO:0016020 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC121835036|UniProtKB=A0ACM8FR70 A0ACM8FR70 LOC121835036 PTHR18934:SF277 ATP-DEPENDENT RNA HELICASE ATP-DEPENDENT RNA HELICASE DHX8 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;ATP-dependent activity#GO:0140657;helicase activity#GO:0004386;isomerase activity#GO:0016853;catalytic activity, acting on RNA#GO:0140098;nucleic acid conformation isomerase activity#GO:0120545;RNA helicase activity#GO:0003724;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;macromolecular conformation isomerase activity#GO:0120543 macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA splicing#GO:0008380;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;mRNA processing#GO:0006397;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions#GO:0000375;nucleic acid biosynthetic process#GO:0141187;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA splicing, via spliceosome#GO:0000398 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic step 2 spliceosome#GO:0071013;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC8023129|UniProtKB=A0ACM8DGF8 A0ACM8DGF8 EMC8-9 PTHR12941:SF10 ER MEMBRANE PROTEIN COMPLEX ER MEMBRANE PROTEIN COMPLEX SUBUNIT 8_9 HOMOLOG molecular carrier activity#GO:0140104;protein carrier activity#GO:0140597;membrane insertase activity#GO:0032977 cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;protein localization to organelle#GO:0033365;cellular component organization#GO:0016043;endoplasmic reticulum organization#GO:0007029;protein insertion into ER membrane#GO:0045048;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein localization#GO:0008104;protein insertion into membrane#GO:0051205;tail-anchored membrane protein insertion into ER membrane#GO:0071816;membrane organization#GO:0061024;endomembrane system organization#GO:0010256;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization to membrane#GO:0090150;cellular process#GO:0009987;establishment of protein localization#GO:0045184 endoplasmic reticulum protein-containing complex#GO:0140534;organelle membrane#GO:0031090;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;EMC complex#GO:0072546;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;membrane protein complex#GO:0098796 IXOSC|EnsemblGenome=LOC121837265|UniProtKB=A0ACM8G316 A0ACM8G316 LOC121837265 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8026031|UniProtKB=A0ACM8FJW3 A0ACM8FJW3 LOC8026031 PTHR33966:SF1 PROTEIN ODR-4 HOMOLOG PROTEIN ODR-4 HOMOLOG macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;localization#GO:0051179 IXOSC|EnsemblGenome=LOC8039388|UniProtKB=A0ACM8DKE0 A0ACM8DKE0 LOC8039388 PTHR24173:SF92 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG B ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8042878|UniProtKB=A0ACM8EN74 A0ACM8EN74 LOC8042878 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of response to stimulus#GO:0048583;regulation of immune response#GO:0050776;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC121046140|UniProtKB=A0ACM8FDF2 A0ACM8FDF2 LOC121046140 PTHR24652:SF70 LOW-DENSITY LIPOPROTEIN RECEPTOR CLASS A DOMAIN-CONTAINING PROTEIN 2 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115319457|UniProtKB=A0ACM8ET26 A0ACM8ET26 LOC115319457 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039109|UniProtKB=A0ACM8DQ75 A0ACM8DQ75 PTHR13162:SF8 CCR4-NOT TRANSCRIPTION COMPLEX CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;regulation of mRNA metabolic process#GO:1903311;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA destabilization#GO:0050779;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;regulation of biological quality#GO:0065008;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;negative regulation of cellular process#GO:0048523;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;positive regulation of catabolic process#GO:0009896;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of primary metabolic process#GO:0080090;nucleobase-containing compound catabolic process#GO:0034655;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;positive regulation of mRNA catabolic process#GO:0061014;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;CCR4-NOT complex#GO:0030014;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 mRNA polyadenylation factor#PC00146 IXOSC|EnsemblGenome=LOC115332042|UniProtKB=A0ACM8G4L5 A0ACM8G4L5 LOC115332042 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837984|UniProtKB=A0ACM8G5Q6 A0ACM8G5Q6 LOC121837984 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8033744|UniProtKB=A0ACM8FEF7 A0ACM8FEF7 PTHR48092:SF9 KNIRPS-RELATED PROTEIN-RELATED KNIRPS-RELATED PROTEIN-RELATED transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;chromatin#GO:0000785;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8039850|UniProtKB=A0ACM8E1Q7 A0ACM8E1Q7 LOC8039850 PTHR42643:SF50 IONOTROPIC RECEPTOR 20A-RELATED IONOTROPIC GLUTAMATE RECEPTOR C-TERMINAL DOMAIN-CONTAINING PROTEIN transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8033650|UniProtKB=A0ACM8DX35 A0ACM8DX35 Nup75 PTHR13373:SF21 FROUNT PROTEIN-RELATED NUCLEAR PORE COMPLEX PROTEIN NUP85 structural constituent of nuclear pore#GO:0017056;structural molecule activity#GO:0005198 establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;gene expression#GO:0010467;intracellular protein transport#GO:0006886;metabolic process#GO:0008152;protein import into nucleus#GO:0006606;protein transport#GO:0015031;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;macromolecule biosynthetic process#GO:0009059;macromolecule localization#GO:0033036;import into nucleus#GO:0051170;nitrogen compound transport#GO:0071705;protein localization to nucleus#GO:0034504;biosynthetic process#GO:0009058;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;intracellular protein localization#GO:0008104;macromolecule metabolic process#GO:0043170;establishment of protein localization to organelle#GO:0072594;establishment of localization#GO:0051234;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;protein localization to organelle#GO:0033365;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleocytoplasmic transport#GO:0006913;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657 intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;membrane-bounded organelle#GO:0043227;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear pore outer ring#GO:0031080;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 structural protein#PC00211 IXOSC|EnsemblGenome=LOC8033628|UniProtKB=A0ACM8DM83 A0ACM8DM83 LOC8033628 PTHR22826:SF211 RHO GUANINE EXCHANGE FACTOR-RELATED LD43457P molecular function regulator activity#GO:0098772;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 protein-binding activity modulator#PC00095;guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC121835826|UniProtKB=A0ACM8FX34 A0ACM8FX34 LOC121835826 PTHR23080:SF63 THAP DOMAIN PROTEIN DDE TNP4 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121837961|UniProtKB=A0ACM8G5M4 A0ACM8G5M4 LOC121837961 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8035847|UniProtKB=A0ACM8DUZ9 A0ACM8DUZ9 LOC8035847 PTHR22811:SF45 TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN TRANSMEMBRANE EMP24 DOMAIN-CONTAINING PROTEIN 6 cargo adaptor activity#GO:0140312;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 Golgi organization#GO:0007030;cellular component organization#GO:0016043;protein transport#GO:0015031;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888;cellular localization#GO:0051641;localization#GO:0051179;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;organelle organization#GO:0006996;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;intracellular protein transport#GO:0006886;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular transport#GO:0046907 cytoplasm#GO:0005737;endomembrane system#GO:0012505;endoplasmic reticulum#GO:0005783;Golgi apparatus#GO:0005794;vesicle#GO:0031982;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;coated vesicle#GO:0030135;membrane-bounded organelle#GO:0043227;COPII-coated ER to Golgi transport vesicle#GO:0030134 membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC8023810|UniProtKB=A0ACM8DYL5 A0ACM8DYL5 LOC8023810 PTHR11702:SF31 DEVELOPMENTALLY REGULATED GTP-BINDING PROTEIN-RELATED MITOCHONDRIAL RIBOSOME-ASSOCIATED GTPASE 2 catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;nucleotide binding#GO:0000166;anion binding#GO:0043168;small molecule binding#GO:0036094;GTPase activity#GO:0003924;ion binding#GO:0043167;hydrolase activity#GO:0016787;ribonucleotide binding#GO:0032553;hydrolase activity, acting on acid anhydrides#GO:0016817;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;nucleoside phosphate binding#GO:1901265;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 IXOSC|EnsemblGenome=LOC115310419|UniProtKB=A0ACM8DPW4 A0ACM8DPW4 LOC115310419 PTHR47978:SF67 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-21 nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl nucleotide binding#GO:0019001;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;GTPase activity#GO:0003924;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120847384|UniProtKB=A0ACM8EC02 A0ACM8EC02 LOC8037695 PTHR10743:SF0 PROTEIN RER1 PROTEIN RER1 cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;protein localization to organelle#GO:0033365;transport#GO:0006810;Golgi vesicle transport#GO:0048193;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;endoplasmic reticulum-Golgi intermediate compartment#GO:0005793;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115312681|UniProtKB=A0ACM8ERK9 A0ACM8ERK9 LOC115312681 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8031431|UniProtKB=A0ACM8EUW1 A0ACM8EUW1 LOC8031431 PTHR11808:SF15 TRANS-SULFURATION ENZYME FAMILY MEMBER CYSTATHIONINE GAMMA-LYASE heterocyclic compound binding#GO:1901363;catalytic activity#GO:0003824;lyase activity#GO:0016829;carbon-sulfur lyase activity#GO:0016846;ion binding#GO:0043167;anion binding#GO:0043168;binding#GO:0005488;small molecule binding#GO:0036094 carboxylic acid biosynthetic process#GO:0046394;homocysteine metabolic process#GO:0050667;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;sulfur compound metabolic process#GO:0006790;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;amino acid biosynthetic process#GO:0008652;proteinogenic amino acid biosynthetic process#GO:0170038 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144;metabolite interconversion enzyme#PC00262 Methionine biosynthesis#P02753>O-Succinyl homoserine lyase#P03026 IXOSC|EnsemblGenome=LOC121832872|UniProtKB=A0ACM8F258 A0ACM8F258 LOC121832872 PTHR46202:SF1 DNA EXCISION REPAIR PROTEIN ERCC-8 DNA EXCISION REPAIR PROTEIN ERCC-8 ubiquitin-like ligase-substrate adaptor activity#GO:1990756;enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 DNA damage response#GO:0006974;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;post-translational protein modification#GO:0043687;proteasomal protein catabolic process#GO:0010498;protein ubiquitination#GO:0016567;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;cellular response to stimulus#GO:0051716;modification-dependent protein catabolic process#GO:0019941;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;protein modification process#GO:0036211;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056 ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;Cul4-RING E3 ubiquitin ligase complex#GO:0080008;nucleotide-excision repair complex#GO:0000109;transferase complex#GO:1990234;protein-containing complex#GO:0032991;nucleus#GO:0005634 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8031111|UniProtKB=A0ACM8DVG3 A0ACM8DVG3 LOC8031111 PTHR47187:SF1 NFATC2-INTERACTING PROTEIN NFATC2-INTERACTING PROTEIN positive regulation of transcription by RNA polymerase II#GO:0045944;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254 IXOSC|EnsemblGenome=LOC115330883|UniProtKB=A0ACM8ECT8 A0ACM8ECT8 LOC115330883 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC8053605|UniProtKB=A0ACM8DM29 A0ACM8DM29 BckdhB PTHR42980:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL transferase complex#GO:1990234;catalytic complex#GO:1902494;oxidoreductase complex#GO:1990204;protein-containing complex#GO:0032991 metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC115316803|UniProtKB=A0ACM8DWF6 A0ACM8DWF6 LOC115316803 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8052568|UniProtKB=A0ACM8FJH7 A0ACM8FJH7 LOC8052568 PTHR11610:SF200 LIPASE FI22312P1 catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;catabolic process#GO:0009056 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8051827|UniProtKB=A0ACM8DLP4 A0ACM8DLP4 LOC8051827 PTHR16043:SF1 DALRD3 PROTEIN DALR ANTICODON-BINDING DOMAIN-CONTAINING PROTEIN 3 nucleic acid binding#GO:0003676;binding#GO:0005488;tRNA binding#GO:0000049;RNA binding#GO:0003723 RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;macromolecule modification#GO:0043412;methylation#GO:0032259;RNA metabolic process#GO:0016070;RNA methylation#GO:0001510;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;tRNA methylation#GO:0030488;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC8038086|UniProtKB=A0ACM8DWE6 A0ACM8DWE6 LOC8038086 PTHR45771:SF6 HOMEOTIC PROTEIN DEFORMED HOMEOTIC PROTEIN SEX COMBS REDUCED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;pattern specification process#GO:0007389;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regionalization#GO:0003002;positive regulation of DNA-templated transcription#GO:0045893;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;developmental process#GO:0032502;anterior/posterior pattern specification#GO:0009952;positive regulation of transcription by RNA polymerase II#GO:0045944 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 DNA-binding transcription factor#PC00218;helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8027430|UniProtKB=A0ACM8DJ27 A0ACM8DJ27 LOC8027430 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8038614|UniProtKB=A0ACM8FWG2 A0ACM8FWG2 LOC8038614 PTHR48032:SF18 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6 mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of macromolecule biosynthetic process#GO:0010556;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8051988|UniProtKB=A0ACM8E834 A0ACM8E834 Ranbp16 PTHR12596:SF2 EXPORTIN 4,7-RELATED EXPORTIN-7 ISOFORM X1 molecular carrier activity#GO:0140104;nucleocytoplasmic carrier activity#GO:0140142 localization#GO:0051179;cellular localization#GO:0051641;nuclear transport#GO:0051169;protein transport#GO:0015031;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;protein export from nucleus#GO:0006611;macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;transport#GO:0006810;intracellular protein transport#GO:0006886 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nuclear envelope#GO:0005635;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle envelope#GO:0031967;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear pore#GO:0005643;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC120845254|UniProtKB=A0ACM8F1B9 A0ACM8F1B9 LOC120845254 PTHR11733:SF242 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED SUBFAMILY NOT NAMED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8036567|UniProtKB=A0ACM8EHM8 A0ACM8EHM8 PTHR23023:SF226 DIMETHYLANILINE MONOOXYGENASE FLAVIN-CONTAINING MONOOXYGENASE oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8052828|UniProtKB=A0ACM8DPF2 A0ACM8DPF2 LOC8052828 PTHR33963:SF2 MKRN2 OPPOSITE STRAND PROTEIN MKRN2 OPPOSITE STRAND PROTEIN IXOSC|EnsemblGenome=LOC120843918|UniProtKB=A0ACM8EX81 A0ACM8EX81 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8034718|UniProtKB=A0ACM8DYE3 A0ACM8DYE3 LOC8034718 PTHR18884:SF136 SEPTIN SEPTIN-1 GTPase activity#GO:0003924;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;ribonucleoside triphosphate phosphatase activity#GO:0017111 cytokinesis#GO:0000910;localization#GO:0051179;cytoskeleton-dependent cytokinesis#GO:0061640;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cell cycle#GO:0007049;cell cycle process#GO:0022402;cell division#GO:0051301;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;cell periphery#GO:0071944;cell cortex#GO:0005938;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;cell division site#GO:0032153;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085 Parkinson disease#P00049>CDCrel-1#P01226 IXOSC|EnsemblGenome=LOC8039394|UniProtKB=A0ACM8EC01 A0ACM8EC01 Tbca PTHR21500:SF0 TUBULIN-SPECIFIC CHAPERONE A TUBULIN-SPECIFIC CHAPERONE A protein binding#GO:0005515;binding#GO:0005488;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular component assembly#GO:0022607;cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;microtubule cytoskeleton#GO:0015630;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856 chaperonin#PC00073 IXOSC|EnsemblGenome=LOC120849115|UniProtKB=A0ACM8F667 A0ACM8F667 LOC120849115 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protease inhibitor#PC00191;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120849877|UniProtKB=A0ACM8FV89 A0ACM8FV89 LOC120849877 PTHR47501:SF9 TRANSPOSASE-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120839945|UniProtKB=A0ACM8EMW0 A0ACM8EMW0 RYBP PTHR12920:SF4 RYBP AND YAF2-RELATED GEO03726P1 DNA binding#GO:0003677;transcription regulator activity#GO:0140110;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC120837455|UniProtKB=A0ACM8EI54 A0ACM8EI54 PTHR31649:SF1 AGAP009604-PA FARNESOIC ACID O-METHYL TRANSFERASE DOMAIN-CONTAINING PROTEIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8039867|UniProtKB=A0ACM8F9D9 A0ACM8F9D9 LOC8039867 PTHR45632:SF34 LD33804P KELCH-LIKE PROTEIN 10 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8030109|UniProtKB=A0ACM8FS82 A0ACM8FS82 LOC8030109 PTHR11069:SF23 GLUCOSYLCERAMIDASE LYSOSOMAL ACID GLUCOSYLCERAMIDASE hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid catabolic process#GO:0016042;glycolipid metabolic process#GO:0006664;catabolic process#GO:0009056;liposaccharide metabolic process#GO:1903509;carbohydrate derivative catabolic process#GO:1901136;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;ceramide metabolic process#GO:0006672 IXOSC|EnsemblGenome=LOC121834187|UniProtKB=A0ACM8FPN2 A0ACM8FPN2 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657 DNA repair#GO:0006281;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;meiotic nuclear division#GO:0140013;nucleobase-containing compound metabolic process#GO:0006139;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;cell cycle#GO:0007049;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;reciprocal homologous recombination#GO:0140527;cellular response to stimulus#GO:0051716;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;nuclear division#GO:0000280;cellular response to stress#GO:0033554;reciprocal meiotic recombination#GO:0007131;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;cell cycle process#GO:0022402;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC120845847|UniProtKB=A0ACM8F098 A0ACM8F098 LOC120845847 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836213|UniProtKB=A0ACM8FZM8 A0ACM8FZM8 LOC120836213 PTHR47272:SF5 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 3 ISOFORM X1 IXOSC|EnsemblGenome=LOC8031451|UniProtKB=A0ACM8FE27 A0ACM8FE27 PTHR16950:SF16 ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4 ZINC TRANSPORTER ZIP13 monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;transition metal ion transmembrane transporter activity#GO:0046915;zinc ion transmembrane transporter activity#GO:0005385 intracellular monoatomic ion homeostasis#GO:0006873;metal ion transport#GO:0030001;homeostatic process#GO:0042592;zinc ion transmembrane transport#GO:0071577;inorganic ion homeostasis#GO:0098771;transition metal ion transport#GO:0000041;monoatomic ion transport#GO:0006811;monoatomic cation transport#GO:0006812;localization#GO:0051179;transmembrane transport#GO:0055085;cellular process#GO:0009987;monoatomic ion homeostasis#GO:0050801;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;zinc ion transport#GO:0006829;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;intracellular monoatomic cation homeostasis#GO:0030003;transport#GO:0006810;intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;establishment of localization#GO:0051234 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;membrane#GO:0016020;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789 transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120841635|UniProtKB=A0ACM8FJR5 A0ACM8FJR5 LOC120841635 PTHR10579:SF178 CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR 1-LIKE ion channel#PC00133 IXOSC|EnsemblGenome=LOC8032272|UniProtKB=A0ACM8DRY9 A0ACM8DRY9 LOC8032272 PTHR12210:SF3 DULLARD PROTEIN PHOSPHATASE MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM50 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;cellular localization#GO:0051641;localization#GO:0051179;protein transport#GO:0015031;protein localization to mitochondrion#GO:0070585;protein localization to organelle#GO:0033365;mitochondrial transport#GO:0006839;intracellular transport#GO:0046907;protein transmembrane transport#GO:0071806;transport#GO:0006810;intracellular protein transport#GO:0006886;protein transmembrane import into intracellular organelle#GO:0044743;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;establishment of protein localization to organelle#GO:0072594;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;protein import into mitochondrial matrix#GO:0030150;mitochondrial protein import pathway#GO:7770058 organelle membrane#GO:0031090;inner mitochondrial membrane protein complex#GO:0098800;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;mitochondrial envelope#GO:0005740;organelle inner membrane#GO:0019866;TIM23 mitochondrial import inner membrane translocase complex#GO:0005744;mitochondrial membrane#GO:0031966;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;organelle envelope#GO:0031967;mitochondrion#GO:0005739 protein phosphatase#PC00195 IXOSC|EnsemblGenome=LOC8026693|UniProtKB=A0ACM8FWJ0 A0ACM8FWJ0 LOC8026693 PTHR48039:SF8 RNA-BINDING MOTIF PROTEIN 14B RNA-BINDING PROTEIN 19-RELATED IXOSC|EnsemblGenome=LOC8037093|UniProtKB=A0ACM8DRL8 A0ACM8DRL8 LOC8037093 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120843958|UniProtKB=A0ACM8EXE0 A0ACM8EXE0 LOC120843958 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120835951|UniProtKB=A0ACM8ECH2 A0ACM8ECH2 PTHR12487:SF7 TEASHIRT-RELATED PROTEIN TEASHIRT-RELATED DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8043710|UniProtKB=A0ACM8FY00 A0ACM8FY00 LOC8043710 PTHR12895:SF9 DYMECLIN DYMECLIN organelle organization#GO:0006996;cellular component organization#GO:0016043;Golgi organization#GO:0007030;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;endomembrane system organization#GO:0010256 organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8038338|UniProtKB=A0ACM8DK67 A0ACM8DK67 LOC8038338 PTHR10264:SF136 BAND 7 PROTEIN-RELATED BAND 7 DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678;channel regulator activity#GO:0016247;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;transporter regulator activity#GO:0141108 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8028208|UniProtKB=A0ACM8EV13 A0ACM8EV13 LOC8028208 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to chemical#GO:0042221;response to stimulus#GO:0050896;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to xenobiotic stimulus#GO:0009410;metabolic process#GO:0008152;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120837999|UniProtKB=A0ACM8EJL4 A0ACM8EJL4 LOC120837999 PTHR12585:SF69 SCC1 / RAD21 FAMILY MEMBER FI11703P binding#GO:0005488;chromatin binding#GO:0003682 recombinational repair#GO:0000725;cellular response to stress#GO:0033554;sister chromatid cohesion#GO:0007062;cell cycle#GO:0007049;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;cell cycle process#GO:0022402;double-strand break repair via homologous recombination#GO:0000724;response to stimulus#GO:0050896;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;DNA recombination#GO:0006310;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;double-strand break repair#GO:0006302;organelle organization#GO:0006996;replication-born double-strand break repair via sister chromatid exchange#GO:1990414;response to stress#GO:0006950;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cohesin complex#GO:0008278;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115319522|UniProtKB=A0ACM8E0A2 A0ACM8E0A2 LOC115319522 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC120840789|UniProtKB=A0ACM8EPQ5 A0ACM8EPQ5 LOC120840789 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN anatomical structure morphogenesis#GO:0009653;heart morphogenesis#GO:0003007;cellular process#GO:0009987;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501;cell adhesion#GO:0007155;developmental process#GO:0032502;post-embryonic development#GO:0009791;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;animal organ development#GO:0048513;anatomical structure development#GO:0048856 extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8030090|UniProtKB=A0ACM8ES18 A0ACM8ES18 LOC8030090 PTHR46753:SF3 FYVE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 1 PDZ DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327695|UniProtKB=A0ACM8EV25 A0ACM8EV25 LOC115327695 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity, acting on DNA#GO:0008094;ATP-dependent activity#GO:0140657;isomerase activity#GO:0016853;DNA helicase activity#GO:0003678;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097;macromolecular conformation isomerase activity#GO:0120543;catalytic activity#GO:0003824;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity, acting on a nucleic acid#GO:0140640 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;response to stimulus#GO:0050896;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;nucleobase-containing compound metabolic process#GO:0006139;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;homologous recombination#GO:0035825;reproductive process#GO:0022414 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC120838384|UniProtKB=A0ACM8EJ57 A0ACM8EJ57 LOC120838384 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC115323547|UniProtKB=A0ACM8E3S7 A0ACM8E3S7 LOC115323547 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC115325334|UniProtKB=A0ACM8EIM1 A0ACM8EIM1 LOC115325334 PTHR10044:SF139 INHIBITOR OF APOPTOSIS DEATH-ASSOCIATED INHIBITOR OF APOPTOSIS 2 transferase activity#GO:0016740;catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;molecular function regulator activity#GO:0098772;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;ubiquitin protein ligase activity#GO:0061630;enzyme regulator activity#GO:0030234;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 negative regulation of biological process#GO:0048519;regulation of programmed cell death#GO:0043067;regulation of protein modification by small protein conjugation or removal#GO:1903320;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of cell cycle#GO:0051726;positive regulation of protein metabolic process#GO:0051247;regulation of post-translational protein modification#GO:1901873;positive regulation of metabolic process#GO:0009893;regulation of primary metabolic process#GO:0080090;regulation of protein metabolic process#GO:0051246;regulation of metabolic process#GO:0019222;negative regulation of programmed cell death#GO:0043069;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;negative regulation of apoptotic process#GO:0043066;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of protein ubiquitination#GO:0031398;biological regulation#GO:0065007;negative regulation of cellular process#GO:0048523;regulation of apoptotic process#GO:0042981;regulation of protein ubiquitination#GO:0031396;regulation of protein modification process#GO:0031399 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8023353|UniProtKB=A0ACM8DGV7 A0ACM8DGV7 LOC8023353 PTHR12735:SF27 BOLA-LIKE PROTEIN-RELATED BOLA-LIKE PROTEIN 2 iron-sulfur cluster binding#GO:0051536;binding#GO:0005488;small molecule binding#GO:0036094 cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;chemical homeostasis#GO:0048878;inorganic ion homeostasis#GO:0098771;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;intracellular iron ion homeostasis#GO:0006879;homeostatic process#GO:0042592;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121838189|UniProtKB=A0ACM8G742 A0ACM8G742 LOC121838189 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8035500|UniProtKB=A0ACM8EW27 A0ACM8EW27 LOC8035500 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8037456|UniProtKB=A0ACM8G6H8 A0ACM8G6H8 LOC8037456 PTHR24247:SF241 5-HYDROXYTRYPTAMINE RECEPTOR 5-HYDROXYTRYPTAMINE RECEPTOR 2A-RELATED signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888;G protein-coupled amine receptor activity#GO:0008227;neurotransmitter receptor activity#GO:0030594 cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway#GO:0007193;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;response to stimulus#GO:0050896;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cell projection#GO:0042995;dendrite#GO:0030425;dendritic tree#GO:0097447 transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;5HT2 type receptor mediated signaling pathway#P04374>5HT2 Receptor#P04414;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GsPCR#P00720 IXOSC|EnsemblGenome=LOC8043247|UniProtKB=A0ACM8E8Z1 A0ACM8E8Z1 LOC8043247 PTHR45965:SF3 INACTIVE RHOMBOID PROTEIN INACTIVE RHOMBOID PROTEIN 1 regulation of localization#GO:0032879;regulation of transport#GO:0051049;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;regulation of secretion#GO:0051046;regulation of protein localization#GO:0032880;regulation of establishment of protein localization#GO:0070201;regulation of secretion by cell#GO:1903530;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of protein transport#GO:0051223;regulation of cell communication#GO:0010646;regulation of biological process#GO:0050789;regulation of ERBB signaling pathway#GO:1901184;regulation of protein secretion#GO:0050708 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115317996|UniProtKB=A0ACM8DY68 A0ACM8DY68 PTHR19139:SF293 AQUAPORIN TRANSPORTER MIP17260P channel activity#GO:0015267;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;passive transmembrane transporter activity#GO:0022803 fluid transport#GO:0042044;water transport#GO:0006833;localization#GO:0051179;establishment of localization#GO:0051234;transport#GO:0006810 apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;apical plasma membrane#GO:0016324;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 transporter#PC00227 IXOSC|EnsemblGenome=LOC8052811|UniProtKB=A0ACM8DX42 A0ACM8DX42 PTHR28541:SF1 DDB1- AND CUL4-ASSOCIATED FACTOR 15 DDB1- AND CUL4-ASSOCIATED FACTOR 15 metabolic process#GO:0008152;protein modification by small protein conjugation or removal#GO:0070647;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 IXOSC|EnsemblGenome=LOC115317847|UniProtKB=A0ACM8FS08 A0ACM8FS08 LOC115317847 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120844748|UniProtKB=A0ACM8EZK6 A0ACM8EZK6 LOC120844748 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC121836022|UniProtKB=A0ACM8FWU7 A0ACM8FWU7 LOC121836022 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040544|UniProtKB=A0ACM8F4R5 A0ACM8F4R5 LOC8040544 PTHR47958:SF215 ATP-DEPENDENT RNA HELICASE DBP3 ATP-DEPENDENT RNA HELICASE DDX17-RELATED binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;ATP-dependent activity#GO:0140657;RNA binding#GO:0003723;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;RNA helicase activity#GO:0003724;nucleic acid conformation isomerase activity#GO:0120545;macromolecular conformation isomerase activity#GO:0120543;helicase activity#GO:0004386;catalytic activity, acting on RNA#GO:0140098;isomerase activity#GO:0016853 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;alternative mRNA splicing, via spliceosome#GO:0000380;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC120841199|UniProtKB=A0ACM8ES65 A0ACM8ES65 LOC120841199 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8036208|UniProtKB=A0ACM8EV76 A0ACM8EV76 LOC8036208 PTHR12854:SF7 ATAXIN 2-RELATED ATAXIN-2 HOMOLOG RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488;mRNA binding#GO:0003729 cellular component organization or biogenesis#GO:0071840;organelle assembly#GO:0070925;cytoplasmic stress granule assembly#GO:0034063;cellular component assembly#GO:0022607;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987 membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC121047158|UniProtKB=A0ACM8FEE1 A0ACM8FEE1 LOC121047158 PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;lytic vacuole#GO:0000323;intracellular organelle#GO:0043229;vacuole#GO:0005773;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;lysosome#GO:0005764 glycosidase#PC00110;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120848266|UniProtKB=A0ACM8F6E6 A0ACM8F6E6 LOC120848266 PTHR46481:SF16 ZINC FINGER BED DOMAIN-CONTAINING PROTEIN 4 BED-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330664|UniProtKB=A0ACM8ECF9 A0ACM8ECF9 LOC115330664 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;ornithine decarboxylase activity#GO:0004586;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;carbon-carbon lyase activity#GO:0016830 polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;metabolic process#GO:0008152;amine metabolic process#GO:0009308;polyamine metabolic process#GO:0006595;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC120836199|UniProtKB=A0ACM8EQP4 A0ACM8EQP4 LOC120836199 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8034248|UniProtKB=A0ACM8FIF3 A0ACM8FIF3 PTHR13465:SF4 UPF0183 PROTEIN PHAF1 PROTEIN CG7083 cellular process#GO:0009987;establishment of protein localization#GO:0045184;establishment of protein localization to membrane#GO:0090150;macromolecule localization#GO:0033036;vesicle-mediated transport#GO:0016192;Golgi vesicle transport#GO:0048193;transport#GO:0006810;protein localization to cell periphery#GO:1990778;intracellular protein localization#GO:0008104;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;protein localization to plasma membrane#GO:0072659;protein localization to membrane#GO:0072657;Golgi to plasma membrane protein transport#GO:0043001;Golgi to plasma membrane transport#GO:0006893;localization within membrane#GO:0051668;establishment of protein localization to plasma membrane#GO:0061951;protein transport#GO:0015031;post-Golgi vesicle-mediated transport#GO:0006892;cellular localization#GO:0051641;localization#GO:0051179 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121833229|UniProtKB=A0ACM8EPD3 A0ACM8EPD3 LOC8029417 PTHR10644:SF27 DNA REPAIR/RNA PROCESSING CPSF FAMILY DNA DAMAGE-BINDING PROTEIN 1 protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;modification-dependent macromolecule catabolic process#GO:0043632;protein metabolic process#GO:0019538;modification-dependent protein catabolic process#GO:0019941;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;catabolic process#GO:0009056;DNA damage response#GO:0006974;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleobase-containing compound metabolic process#GO:0006139;proteasomal protein catabolic process#GO:0010498 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;membraneless organelle#GO:0043228;nucleus#GO:0005634;chromosome#GO:0005694;site of double-strand break#GO:0035861;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA metabolism protein#PC00031;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8036739|UniProtKB=A0ACM8E5C1 A0ACM8E5C1 LOC8036739 PTHR43539:SF23 FLAVIN-BINDING MONOOXYGENASE-LIKE PROTEIN (AFU_ORTHOLOGUE AFUA_4G09220) FAD-DEPENDENT OXIDOREDUCTASE DOMAIN-CONTAINING PROTEIN 2 ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;response to stress#GO:0006950;cellular process#GO:0009987;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to endoplasmic reticulum stress#GO:0034976;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;catabolic process#GO:0009056 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;endoplasmic reticulum lumen#GO:0005788 oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115332172|UniProtKB=A0ACM8EYR0 A0ACM8EYR0 LOC115332172 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8027136|UniProtKB=A0ACM8FWD8 A0ACM8FWD8 LOC8027136 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC115309410|UniProtKB=A0ACM8DNN1 A0ACM8DNN1 LOC115309410 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120843465|UniProtKB=A0ACM8EXA2 A0ACM8EXA2 LOC120843465 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC121836703|UniProtKB=A0ACM8G0P9 A0ACM8G0P9 LOC121836703 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835268|UniProtKB=A0ACM8FSY4 A0ACM8FSY4 LOC121835268 PTHR11802:SF201 SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE SERINE CARBOXYPEPTIDASE CTSA-1.1 carboxypeptidase activity#GO:0004180;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;exopeptidase activity#GO:0008238;serine-type peptidase activity#GO:0008236;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8024454|UniProtKB=A0ACM8E147 A0ACM8E147 mRpL1 PTHR36427:SF5 54S RIBOSOMAL PROTEIN L1, MITOCHONDRIAL LARGE RIBOSOMAL SUBUNIT PROTEIN UL1M structural molecule activity#GO:0005198;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of protein metabolic process#GO:0051246;regulation of translation#GO:0006417;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;post-transcriptional regulation of gene expression#GO:0010608;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;mitochondrial ribosome#GO:0005761;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8034692|UniProtKB=A0ACM8DZT3 A0ACM8DZT3 LOC8034692 PTHR16130:SF2 LYSOSOMAL COBALAMIN TRANSPORTER-RELATED LYSOSOMAL COBALAMIN TRANSPORTER-RELATED macromolecule localization#GO:0033036;protein localization to vacuole#GO:0072665;protein localization to organelle#GO:0033365;localization#GO:0051179;intracellular protein localization#GO:0008104 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membrane#GO:0016020;bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;vacuolar membrane#GO:0005774;intracellular organelle#GO:0043229 transporter#PC00227 IXOSC|EnsemblGenome=LOC120844621|UniProtKB=A0ACM8EYT1 A0ACM8EYT1 LOC120844621 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318793|UniProtKB=A0ACM8G4E5 A0ACM8G4E5 LOC115318793 PTHR24390:SF79 ZINC FINGER PROTEIN LD33778P sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121837783|UniProtKB=A0ACM8G550 A0ACM8G550 LOC121837783 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8052882|UniProtKB=A0ACM8FIR4 A0ACM8FIR4 LOC8052882 PTHR39069:SF11 ECDYSONE-INDUCIBLE GENE E1, ISOFORM A EB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840003|UniProtKB=A0ACM8G8C5 A0ACM8G8C5 LOC120840003 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8035476|UniProtKB=A0ACM8DZR6 A0ACM8DZR6 Gbeta13F PTHR19850:SF25 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-1 signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 cell periphery#GO:0071944;membrane#GO:0016020;cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cytoplasmic side of membrane#GO:0098562;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;cellular anatomical structure#GO:0110165;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552 protein-binding activity modulator#PC00095;heterotrimeric G-protein#PC00117;G-protein#PC00020 Wnt signaling pathway#P00057>GBeta#P01457;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;PI3 kinase pathway#P00048>Gbetagamma#P01188;Opioid proenkephalin pathway#P05915>G-protein#P05994;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Gbeta#P00710;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta#P00753;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;Enkephalin release#P05913>G-Protein (s)#P05977;Enkephalin release#P05913>G-Protein (i)#P05974;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>Gbeta#P00727;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458 IXOSC|EnsemblGenome=LOC8038497|UniProtKB=A0ACM8DS05 A0ACM8DS05 LOC8038497 PTHR22973:SF12 LD35087P LD35087P IXOSC|EnsemblGenome=LOC115328884|UniProtKB=A0ACM8FRQ6 A0ACM8FRQ6 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051436|UniProtKB=A0ACM8DLR9 A0ACM8DLR9 LOC8051436 PTHR24083:SF193 NUCLEAR HORMONE RECEPTOR PROTEIN ULTRASPIRACLE sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulatory region nucleic acid binding#GO:0001067 cellular response to chemical stimulus#GO:0070887;animal gross anatomical part developmental process#GO:0160108;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;hormone-mediated signaling pathway#GO:0009755;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;cellular response to hormone stimulus#GO:0032870;signaling#GO:0023052;positive regulation of transcription by RNA polymerase II#GO:0045944;multicellular organism development#GO:0007275;response to hormone#GO:0009725;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of macromolecule metabolic process#GO:0010604;response to chemical#GO:0042221;nervous system development#GO:0007399;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;intracellular signal transduction#GO:0035556;cellular response to stimulus#GO:0051716;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;intracellular receptor signaling pathway#GO:0030522;positive regulation of RNA metabolic process#GO:0051254;developmental process#GO:0032502;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;nuclear receptor-mediated signaling pathway#GO:0141193;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007 nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8024924|UniProtKB=A0ACM8EPC0 A0ACM8EPC0 LOC8024924 PTHR12270:SF25 GLYCOSYLTRANSFERASE-RELATED GLYCOSYLTRANSFERASE-LIKE PROTEIN LARGE glucuronosyltransferase activity#GO:0015020;pentosyltransferase activity#GO:0016763;xylosyltransferase activity#GO:0042285;catalytic activity#GO:0003824;transferase activity#GO:0016740;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;UDP-glycosyltransferase activity#GO:0008194 carbohydrate derivative metabolic process#GO:1901135;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;cellular process#GO:0009987;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;glycoprotein metabolic process#GO:0009100;protein O-linked glycosylation via mannose#GO:0035269;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 glycosyltransferase#PC00111;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121837660|UniProtKB=A0ACM8G442 A0ACM8G442 LOC121837660 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8053530|UniProtKB=A0ACM8EXA5 A0ACM8EXA5 Wdr81 PTHR46866:SF1 GH12955P GH12955P regulation of transport#GO:0051049;regulation of localization#GO:0032879;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;positive regulation of transport#GO:0051050;regulation of vesicle-mediated transport#GO:0060627 membrane-bounded organelle#GO:0043227;early endosome#GO:0005769;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;late endosome#GO:0005770;vesicle#GO:0031982;intracellular vesicle#GO:0097708 IXOSC|EnsemblGenome=LOC8034924|UniProtKB=A0ACM8DJN8 A0ACM8DJN8 LOC8034924 PTHR11195:SF13 DESTABILASE-RELATED LYSOZYME hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;peptidoglycan muralytic activity#GO:0061783;catalytic activity#GO:0003824;lysozyme activity#GO:0003796;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 serine protease#PC00203;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115315181|UniProtKB=A0ACM8EZG8 A0ACM8EZG8 LOC115315181 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8036754|UniProtKB=A0ACM8DHN4 A0ACM8DHN4 LOC8036754 PTHR39069:SF11 ECDYSONE-INDUCIBLE GENE E1, ISOFORM A EB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8042565|UniProtKB=A0ACM8DKV5 A0ACM8DKV5 LOC8042565 PTHR11153:SF8 SIDEROFLEXIN SIDEROFLEXIN-1 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 mitochondrial transmembrane transport#GO:1990542;transmembrane transport#GO:0055085;cellular localization#GO:0051641;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;localization#GO:0051179;mitochondrial transport#GO:0006839;carboxylic acid transmembrane transport#GO:1905039;intracellular transport#GO:0046907;transport#GO:0006810;carboxylic acid transport#GO:0046942;organic acid transport#GO:0015849;amino acid transport#GO:0006865;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;organelle envelope#GO:0031967;mitochondrial inner membrane#GO:0005743;membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8053192|UniProtKB=A0ACM8DR85 A0ACM8DR85 alphaCOP PTHR19876:SF1 COATOMER COATOMER SUBUNIT ALPHA retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234 cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;endomembrane system#GO:0012505;COPI-coated vesicle#GO:0030137;cytoplasm#GO:0005737;vesicle coat#GO:0030120;membrane#GO:0016020;vesicle membrane#GO:0012506;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi-associated vesicle#GO:0005798;Golgi apparatus#GO:0005794;cellular anatomical structure#GO:0110165;COPI vesicle coat#GO:0030126;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;coated vesicle membrane#GO:0030662;Golgi-associated vesicle membrane#GO:0030660;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982;membrane coat#GO:0030117;coated membrane#GO:0048475;cytoplasmic vesicle#GO:0031410;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC115328785|UniProtKB=A0ACM8E8Q4 A0ACM8E8Q4 LOC115328785 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115328924|UniProtKB=A0ACM8E8S6 A0ACM8E8S6 LOC115328924 PTHR44229:SF4 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] CHAIN DEHYDROGENASE_REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02990)-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115317887|UniProtKB=A0ACM8DYA1 A0ACM8DYA1 LOC115317887 PTHR10858:SF23 DEOXYRIBONUCLEASE II DEOXYRIBONUCLEASE II hydrolase activity#GO:0016787;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;catalytic activity, acting on DNA#GO:0140097;endonuclease activity#GO:0004519;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;DNA nuclease activity#GO:0004536 catabolic process#GO:0009056;execution phase of apoptosis#GO:0097194;apoptotic process#GO:0006915;cell death#GO:0008219;cellular component organization#GO:0016043;nucleic acid metabolic process#GO:0090304;programmed cell death#GO:0012501;primary metabolic process#GO:0044238;cellular component disassembly#GO:0022411;DNA catabolic process#GO:0006308;nucleobase-containing compound metabolic process#GO:0006139;apoptotic DNA fragmentation#GO:0006309;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;DNA metabolic process#GO:0006259 endodeoxyribonuclease#PC00093 IXOSC|EnsemblGenome=LOC121837369|UniProtKB=A0ACM8G3C5 A0ACM8G3C5 LOC121837369 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120850776|UniProtKB=A0ACM8FM38 A0ACM8FM38 LOC120850776 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 sphingolipid biosynthetic process#GO:0030148;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycosphingolipid biosynthetic process#GO:0006688;carbohydrate derivative biosynthetic process#GO:1901137;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;lipid biosynthetic process#GO:0008610;glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;biosynthetic process#GO:0009058 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115314744|UniProtKB=A0ACM8G542 A0ACM8G542 LOC115314744 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115325077|UniProtKB=A0ACM8FVN2 A0ACM8FVN2 LOC115325077 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8035798|UniProtKB=A0ACM8EJK6 A0ACM8EJK6 LOC8035798 PTHR13220:SF11 TIMELESS INTERACTING-RELATED TIMELESS-INTERACTING PROTEIN DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of metabolic process#GO:0019222;response to stress#GO:0006950;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of DNA metabolic process#GO:0051053;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;DNA metabolic process#GO:0006259;negative regulation of cellular process#GO:0048523;negative regulation of DNA-templated DNA replication#GO:2000104;metabolic process#GO:0008152;DNA damage response#GO:0006974;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;regulation of DNA metabolic process#GO:0051052;DNA replication#GO:0006260;regulation of DNA-templated DNA replication#GO:0090329;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;cellular response to stress#GO:0033554;regulation of DNA replication#GO:0006275;DNA-templated DNA replication#GO:0006261;negative regulation of nucleobase-containing compound metabolic process#GO:0045934 nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;replication fork#GO:0005657;organelle lumen#GO:0043233;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;nuclear replication fork#GO:0043596 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8044099|UniProtKB=A0ACM8E150 A0ACM8E150 LOC8044099 PTHR23042:SF76 CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR HOMOLOG RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;signaling receptor complex#GO:0043235;intracellular organelle#GO:0043229 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120839077|UniProtKB=A0ACM8G5C7 A0ACM8G5C7 LOC120839077 PTHR11006:SF125 PROTEIN ARGININE N-METHYLTRANSFERASE PROTEIN ARGININE N-METHYLTRANSFERASE 3 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;N-methyltransferase activity#GO:0008170;histone methyltransferase activity#GO:0042054;histone modifying activity#GO:0140993;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;protein methyltransferase activity#GO:0008276;catalytic activity, acting on a protein#GO:0140096 regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;chromatin organization#GO:0006325;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8051189|UniProtKB=A0ACM8DLV3 A0ACM8DLV3 LOC8051189 PTHR44360:SF1 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 DNAJ HOMOLOG SUBFAMILY B MEMBER 9 binding#GO:0005488;protein-folding chaperone binding#GO:0051087;protein binding#GO:0005515 macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;response to chemical#GO:0042221;proteasomal protein catabolic process#GO:0010498;response to stress#GO:0006950;cellular process#GO:0009987;protein metabolic process#GO:0019538;ERAD pathway#GO:0036503;response to endoplasmic reticulum stress#GO:0034976;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;catabolic process#GO:0009056;response to stimulus#GO:0050896;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;endoplasmic reticulum lumen#GO:0005788;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8029013|UniProtKB=A0ACM8F941 A0ACM8F941 LOC8029013 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824 hydrogen peroxide metabolic process#GO:0042743;biosynthetic process#GO:0009058;cellular process#GO:0009987;reactive oxygen species metabolic process#GO:0072593;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;peroxisomal matrix#GO:0005782;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;peroxisome#GO:0005777;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;microbody#GO:0042579 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8053173|UniProtKB=A0ACM8EHN8 A0ACM8EHN8 LOC8053173 PTHR12395:SF9 DOM-3 RELATED DECAPPING AND EXORIBONUCLEASE PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;catalytic activity, acting on RNA#GO:0140098;phosphoric ester hydrolase activity#GO:0042578;phosphatase activity#GO:0016791;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824 RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;nucleic acid metabolic process#GO:0090304;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;macromolecule catabolic process#GO:0009057;negative regulation of cellular process#GO:0048523;metabolic process#GO:0008152;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cytosol#GO:0005829;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8041048|UniProtKB=A0ACM8E0L3 A0ACM8E0L3 PTHR14588:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 10 DDB1- AND CUL4-ASSOCIATED FACTOR 10 protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151;cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 IXOSC|EnsemblGenome=LOC8036382|UniProtKB=A0ACM8DUE9 A0ACM8DUE9 LOC8036382 PTHR11616:SF328 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER carboxylic acid transmembrane transporter activity#GO:0046943;symporter activity#GO:0015293;amino acid:sodium symporter activity#GO:0005283;monoatomic cation transmembrane transporter activity#GO:0008324;solute:sodium symporter activity#GO:0015370;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;active transmembrane transporter activity#GO:0022804;L-amino acid transmembrane transporter activity#GO:0015179;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294 cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725;nitrogen compound transport#GO:0071705;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;carboxylic acid transport#GO:0046942;establishment of localization#GO:0051234;import into cell#GO:0098657;sodium ion transport#GO:0006814;carboxylic acid transmembrane transport#GO:1905039;metal ion transport#GO:0030001;import across plasma membrane#GO:0098739;glycine transport#GO:0015816;monoatomic ion transport#GO:0006811;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8023130|UniProtKB=A0ACM8E8L7 A0ACM8E8L7 LOC8023130 PTHR46181:SF3 MITOCHONDRIAL GLYCINE TRANSPORTER MITOCHONDRIAL GLYCINE TRANSPORTER glycine transmembrane transporter activity#GO:0015187;amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;carboxylic acid transmembrane transporter activity#GO:0046943;neutral L-amino acid transmembrane transporter activity#GO:0015175 cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;organic acid transport#GO:0015849;amino acid transport#GO:0006865;transport#GO:0006810;carboxylic acid transport#GO:0046942;intracellular transport#GO:0046907;establishment of localization#GO:0051234;carboxylic acid transmembrane transport#GO:1905039;mitochondrial transport#GO:0006839;mitochondrial transmembrane transport#GO:1990542;glycine transport#GO:0015816;neutral amino acid transport#GO:0015804;cellular localization#GO:0051641;transmembrane transport#GO:0055085;amino acid transmembrane transport#GO:0003333;localization#GO:0051179 mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transporter#PC00227 IXOSC|EnsemblGenome=LOC120839305|UniProtKB=A0ACM8EMA1 A0ACM8EMA1 LOC120839305 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836129|UniProtKB=A0ACM8FWW9 A0ACM8FWW9 LOC121836129 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8036518|UniProtKB=A0ACM8DUU7 A0ACM8DUU7 LOC8036518 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC121045905|UniProtKB=A0ACM8FBA8 A0ACM8FBA8 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC8026679|UniProtKB=A0ACM8FC89 A0ACM8FC89 LOC8026679 PTHR10662:SF22 NUCLEAR RNA EXPORT FACTOR NUCLEAR RNA EXPORT FACTOR 1 RNA binding#GO:0003723;nucleic acid binding#GO:0003676;binding#GO:0005488 nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;localization#GO:0051179;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913;gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120844538|UniProtKB=A0ACM8F002 A0ACM8F002 LOC120844538 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8036061|UniProtKB=A0ACM8DJW7 A0ACM8DJW7 LOC8036061 PTHR11559:SF370 CARBOXYLESTERASE CARBOXYLIC ESTER HYDROLASE-RELATED esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067 IXOSC|EnsemblGenome=LOC115310623|UniProtKB=A0ACM8DPX1 A0ACM8DPX1 LOC115310623 PTHR22988:SF73 MYOTONIC DYSTROPHY S/T KINASE-RELATED RHO-ASSOCIATED PROTEIN KINASE-RELATED catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674 cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;signaling#GO:0023052;actomyosin structure organization#GO:0031032;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;cytokinesis#GO:0000910;Rho protein signal transduction#GO:0007266;cytoskeleton-dependent cytokinesis#GO:0061640;cellular process#GO:0009987;signal transduction#GO:0007165;organelle organization#GO:0006996;intracellular signaling cassette#GO:0141124;embryo development#GO:0009790;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;embryonic morphogenesis#GO:0048598;cell division#GO:0051301;cellular response to stimulus#GO:0051716;cell cycle#GO:0007049;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;mitotic cytokinesis#GO:0000281;regulation of cytoskeleton organization#GO:0051493;mitotic cell cycle#GO:0000278;actin filament-based process#GO:0030029;regulation of cell junction assembly#GO:1901888;cortical cytoskeleton organization#GO:0030865;intracellular signal transduction#GO:0035556;anatomical structure development#GO:0048856;cortical actin cytoskeleton organization#GO:0030866;cell communication#GO:0007154;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;developmental process#GO:0032502;regulation of actin filament-based process#GO:0032970;mitotic cell cycle process#GO:1903047 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-receptor serine/threonine protein kinase#PC00167 Cytoskeletal regulation by Rho GTPase#P00016>ROCK#P00519 IXOSC|EnsemblGenome=LOC115314939|UniProtKB=A0ACM8DUN4 A0ACM8DUN4 LOC115314939 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120845264|UniProtKB=A0ACM8F1C9 A0ACM8F1C9 LOC120845264 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8028716|UniProtKB=A0ACM8DH43 A0ACM8DH43 LOC8028716 PTHR47204:SF1 OS02G0168900 PROTEIN PHAGE TAIL PROTEIN IXOSC|EnsemblGenome=LOC115328704|UniProtKB=A0ACM8EY33 A0ACM8EY33 LOC115328704 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121833982|UniProtKB=A0ACM8FPS6 A0ACM8FPS6 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;catalytic activity, acting on DNA#GO:0140097;helicase activity#GO:0004386;ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094 nucleobase-containing compound metabolic process#GO:0006139;DNA repair#GO:0006281;DNA damage response#GO:0006974;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cell cycle#GO:0007049;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;homologous recombination#GO:0035825;reproductive process#GO:0022414;meiosis I cell cycle process#GO:0061982;sexual reproduction#GO:0019953;organelle fission#GO:0048285;response to stress#GO:0006950;organelle organization#GO:0006996;cellular process#GO:0009987;nucleotide-excision repair#GO:0006289;DNA metabolic process#GO:0006259;meiotic cell cycle#GO:0051321;metabolic process#GO:0008152;DNA recombination#GO:0006310;cellular component organization or biogenesis#GO:0071840;double-strand break repair#GO:0006302;meiosis I#GO:0007127;cellular component organization#GO:0016043;meiotic cell cycle process#GO:1903046;cell cycle process#GO:0022402;response to stimulus#GO:0050896;nuclear division#GO:0000280;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC115317277|UniProtKB=A0ACM8EHI7 A0ACM8EHI7 PTHR21600:SF40 MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE PSEUDOURIDYLATE SYNTHASE RPUSD2 intramolecular transferase activity#GO:0016866;catalytic activity#GO:0003824;isomerase activity#GO:0016853 macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;metabolic process#GO:0008152;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;RNA biosynthetic process#GO:0032774;pseudouridine synthesis#GO:0001522;rRNA modification#GO:0000154;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8032591|UniProtKB=A0ACM8FMC2 A0ACM8FMC2 LOC8032591 PTHR43568:SF1 P PROTEIN CITRATE TRANSPORTER-LIKE DOMAIN-CONTAINING PROTEIN-RELATED transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8035409|UniProtKB=A0ACM8G0G2 A0ACM8G0G2 LOC8035409 PTHR10342:SF275 ARYLSULFATASE RE14504P hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 IXOSC|EnsemblGenome=LOC115324003|UniProtKB=A0ACM8G2W0 A0ACM8G2W0 LOC115324003 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029048|UniProtKB=A0ACM8DPF7 A0ACM8DPF7 PTHR10900:SF126 PERIOSTIN-RELATED MUCIN-5AC-RELATED protein binding#GO:0005515;cell adhesion molecule binding#GO:0050839;binding#GO:0005488 extracellular structure organization#GO:0043062;cell adhesion#GO:0007155;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;cell-cell adhesion#GO:0098609;cellular component organization#GO:0016043;homophilic cell-cell adhesion#GO:0007156;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8031108|UniProtKB=A0ACM8DHY8 A0ACM8DHY8 LOC8031108 PTHR10281:SF121 MEMBRANE-ASSOCIATED PROGESTERONE RECEPTOR COMPONENT-RELATED VACUOLE MEMBRANE PROTEIN 1 transporter activity#GO:0005215;phospholipid scramblase activity#GO:0017128;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;intramembrane lipid carrier activity#GO:0140303 catabolic process#GO:0009056;cellular component organization#GO:0016043;Golgi organization#GO:0007030;vacuole organization#GO:0007033;process utilizing autophagic mechanism#GO:0061919;organelle assembly#GO:0070925;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;macroautophagy#GO:0016236;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagy#GO:0006914;autophagosome organization#GO:1905037;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;metabolic process#GO:0008152 intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membrane#GO:0016020;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120849526|UniProtKB=A0ACM8F8A9 A0ACM8F8A9 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED biological regulation#GO:0065007;regulation of immune system process#GO:0002682;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8031386|UniProtKB=A0ACM8DI69 A0ACM8DI69 LOC8031386 PTHR10177:SF527 CYCLINS CYCLIN D, ISOFORM D cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;enzyme regulator activity#GO:0030234 G1/S transition of mitotic cell cycle#GO:0000082;positive regulation of cell cycle G1/S phase transition#GO:1902808;positive regulation of mitotic cell cycle#GO:0045931;mitotic cell cycle process#GO:1903047;regulation of mitotic cell cycle#GO:0007346;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cell cycle G1/S phase transition#GO:0044843;positive regulation of cell cycle#GO:0045787;regulation of cell cycle process#GO:0010564;biological regulation#GO:0065007;mitotic cell cycle phase transition#GO:0044772;regulation of G1/S transition of mitotic cell cycle#GO:2000045;regulation of mitotic cell cycle phase transition#GO:1901990;cell cycle#GO:0007049;regulation of cell cycle phase transition#GO:1901987;cell cycle process#GO:0022402;positive regulation of cell cycle process#GO:0090068;regulation of biological process#GO:0050789;cell cycle phase transition#GO:0044770;regulation of cellular process#GO:0050794;mitotic cell cycle#GO:0000278;regulation of cell cycle#GO:0051726;regulation of cell cycle G1/S phase transition#GO:1902806 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;transferase complex#GO:1990234;membraneless organelle#GO:0043228;protein kinase complex#GO:1902911 kinase activator#PC00138 Cell cycle#P00013>Cyclin D#P00484;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 IXOSC|EnsemblGenome=LOC115309999|UniProtKB=A0ACM8DP70 A0ACM8DP70 LOC115309999 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8041871|UniProtKB=A0ACM8DS64 A0ACM8DS64 SCaMC PTHR24089:SF769 SOLUTE CARRIER FAMILY 25 MITOCHONDRIAL ADENYL NUCLEOTIDE ANTIPORTER SCAMC transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 nucleobase-containing compound transport#GO:0015931;organophosphate ester transport#GO:0015748;localization#GO:0051179;establishment of localization#GO:0051234;nitrogen compound transport#GO:0071705;transport#GO:0006810;carbohydrate derivative transport#GO:1901264 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 mitochondrial carrier protein#PC00158;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120849166|UniProtKB=A0ACM8F764 A0ACM8F764 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121048224|UniProtKB=A0ACM8FGI8 A0ACM8FGI8 LOC121048224 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8025629|UniProtKB=A0ACM8EZW6 A0ACM8EZW6 LOC8025629 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC121836138|UniProtKB=A0ACM8FYF5 A0ACM8FYF5 LOC121836138 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120848549|UniProtKB=A0ACM8FPR1 A0ACM8FPR1 PTHR24345:SF99 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301 cellular process#GO:0009987;cell cycle process#GO:0022402;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cellular component organization#GO:0016043;organelle organization#GO:0006996;cell cycle#GO:0007049;cytoskeleton organization#GO:0007010;mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687;membrane-bounded organelle#GO:0043227;kinetochore#GO:0000776;chromosome#GO:0005694;spindle pole#GO:0000922;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;centrosome#GO:0005813;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC121836144|UniProtKB=A0ACM8FX15 A0ACM8FX15 LOC121836144 PTHR47272:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN ZINC FINGER PROTEIN 576, TANDEM DUPLICATE 1 IXOSC|EnsemblGenome=LOC115308186|UniProtKB=A0ACM8EVM1 A0ACM8EVM1 LOC115308186 PTHR24412:SF505 KELCH PROTEIN BTB DOMAIN-CONTAINING PROTEIN enzyme-substrate adaptor activity#GO:0140767;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 catalytic complex#GO:1902494;transferase complex#GO:1990234;Cul3-RING ubiquitin ligase complex#GO:0031463;ubiquitin ligase complex#GO:0000151;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;cullin-RING ubiquitin ligase complex#GO:0031461;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC121832863|UniProtKB=A0ACM8FJR2 A0ACM8FJR2 LOC121833233 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121834723|UniProtKB=A0ACM8FR66 A0ACM8FR66 PTHR10782:SF108 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN TONALLI, ISOFORM E SUMO ligase activity#GO:0061665;transcription regulator activity#GO:0140110;SUMO transferase activity#GO:0019789;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;molecular function inhibitor activity#GO:0140678;catalytic activity#GO:0003824;transferase activity#GO:0016740;transcription coregulator activity#GO:0003712;molecular function regulator activity#GO:0098772;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transcription coactivator activity#GO:0003713 regulation of response to stimulus#GO:0048583;regulation of receptor signaling pathway via JAK-STAT#GO:0046425;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of signal transduction#GO:0009966;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of response to stimulus#GO:0048585;regulation of RNA metabolic process#GO:0051252;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;protein modification process#GO:0036211;regulation of receptor signaling pathway via STAT#GO:1904892;regulation of cell communication#GO:0010646;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;metabolic process#GO:0008152;protein sumoylation#GO:0016925;cellular process#GO:0009987;negative regulation of signal transduction#GO:0009968;regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;protein modification by small protein conjugation or removal#GO:0070647;negative regulation of cell communication#GO:0010648;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;negative regulation of biological process#GO:0048519;regulation of transcription by RNA polymerase II#GO:0006357 membraneless organelle#GO:0043228;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121046784|UniProtKB=A0ACM8FDL0 A0ACM8FDL0 LOC121046784 PTHR48626:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115330188|UniProtKB=A0ACM8EAW4 A0ACM8EAW4 LOC115330188 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC120846390|UniProtKB=A0ACM8F348 A0ACM8F348 LOC120846390 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC120849125|UniProtKB=A0ACM8F674 A0ACM8F674 LOC120849125 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8039787|UniProtKB=A0ACM8DKF5 A0ACM8DKF5 LOC8039787 PTHR47978:SF40 FAMILY NOT NAMED RAS-RELATED PROTEIN RAB-33 GTPase activity#GO:0003924;ion binding#GO:0043167;anion binding#GO:0043168;small molecule binding#GO:0036094;hydrolase activity#GO:0016787;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;nucleotide binding#GO:0000166;ribonucleoside triphosphate phosphatase activity#GO:0017111;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363 intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;endosome#GO:0005768;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC8043671|UniProtKB=A0ACM8EK77 A0ACM8EK77 Sas-4 PTHR10331:SF29 T COMPLEX PROTEIN 10 SPINDLE ASSEMBLY ABNORMAL 4 cytoskeletal protein binding#GO:0008092;tubulin binding#GO:0015631;binding#GO:0005488;protein binding#GO:0005515 cell projection organization#GO:0030030;centrosome cycle#GO:0007098;cell cycle process#GO:0022402;cell cycle#GO:0007049;cellular component organization#GO:0016043;cilium assembly#GO:0060271;membraneless organelle assembly#GO:0140694;cilium organization#GO:0044782;microtubule cytoskeleton organization#GO:0000226;centriole replication#GO:0007099;organelle assembly#GO:0070925;cytoskeleton organization#GO:0007010;plasma membrane bounded cell projection organization#GO:0120036;cellular component assembly#GO:0022607;cell projection assembly#GO:0030031;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;microtubule organizing center organization#GO:0031023;centrosome duplication#GO:0051298;microtubule-based process#GO:0007017;cellular component organization or biogenesis#GO:0071840;plasma membrane bounded cell projection assembly#GO:0120031 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;microtubule organizing center#GO:0005815;centrosome#GO:0005813;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630 microtubule or microtubule-binding cytoskeletal protein#PC00157;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120841010|UniProtKB=A0ACM8EQL6 A0ACM8EQL6 LOC120841010 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;cellular anatomical structure#GO:0110165 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8038987|UniProtKB=A0ACM8EX07 A0ACM8EX07 LOC8038987 PTHR12247:SF129 POLYCOMB GROUP PROTEIN SOP-2-RELATED PROTEIN 3 chromatin binding#GO:0003682;histone binding#GO:0042393;binding#GO:0005488;protein binding#GO:0005515 negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8029915|UniProtKB=A0ACM8EJ49 A0ACM8EJ49 LOC8029915 PTHR45758:SF20 MITOFERRIN-1-RELATED MITOFERRIN-2 transition metal ion transmembrane transporter activity#GO:0046915;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;iron ion transmembrane transporter activity#GO:0005381;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation transmembrane transporter activity#GO:0008324;metal ion transmembrane transporter activity#GO:0046873 cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;transition metal ion transport#GO:0000041;transport#GO:0006810;iron ion transmembrane transport#GO:0034755;iron ion transport#GO:0006826;monoatomic ion transport#GO:0006811;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;localization#GO:0051179 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;organelle envelope#GO:0031967;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8033151|UniProtKB=A0ACM8DHH8 A0ACM8DHH8 LOC8033151 PTHR15949:SF3 TESTIS-EXPRESSED PROTEIN 264 TESTIS-EXPRESSED PROTEIN 264 macroautophagy#GO:0016236;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;autophagy#GO:0006914;reticulophagy#GO:0061709;response to stress#GO:0006950;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;process utilizing autophagic mechanism#GO:0061919;cellular response to stress#GO:0033554 endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;membraneless organelle#GO:0043228;vacuolar membrane#GO:0005774;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;nucleus#GO:0005634;endomembrane system#GO:0012505;intracellular membraneless organelle#GO:0043232;vacuole#GO:0005773;cytoplasm#GO:0005737;autophagosome#GO:0005776;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;autophagosome membrane#GO:0000421;intracellular anatomical structure#GO:0005622;chromosome#GO:0005694;replication fork#GO:0005657;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC121836453|UniProtKB=A0ACM8FY89 A0ACM8FY89 LOC121836453 PTHR11533:SF294 PROTEASE M1 ZINC METALLOPROTEASE THYROTROPIN-RELEASING HORMONE-DEGRADING ECTOENZYME catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;catalytic activity#GO:0003824;aminopeptidase activity#GO:0004177;metalloexopeptidase activity#GO:0008235;exopeptidase activity#GO:0008238;metalloaminopeptidase activity#GO:0070006;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237 peptide catabolic process#GO:0043171;cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;proteolysis#GO:0006508;metabolic process#GO:0008152;peptide metabolic process#GO:0006518;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8028781|UniProtKB=A0ACM8F7Z8 A0ACM8F7Z8 LOC8028781 PTHR12318:SF0 TESTOSTERONE-REGULATED PROTEIN RP2 ACYL-COENZYME A DIPHOSPHATASE NUDT19 IXOSC|EnsemblGenome=LOC120837138|UniProtKB=A0ACM8EHN7 A0ACM8EHN7 LOC120837138 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115328309|UniProtKB=A0ACM8FF33 A0ACM8FF33 LOC115328309 PTHR21614:SF0 SHORT COILED COIL PROTEIN SHORT COILED-COIL PROTEIN intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;Golgi apparatus subcompartment#GO:0098791 IXOSC|EnsemblGenome=LOC8025044|UniProtKB=A0ACM8DIY3 A0ACM8DIY3 LOC8025044 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8035390|UniProtKB=A0ACM8EGT1 A0ACM8EGT1 Tpi PTHR21139:SF2 TRIOSEPHOSPHATE ISOMERASE TRIOSEPHOSPHATE ISOMERASE intramolecular oxidoreductase activity#GO:0016860;isomerase activity#GO:0016853;catalytic activity#GO:0003824;intramolecular oxidoreductase activity, interconverting aldoses and ketoses#GO:0016861 gluconeogenesis#GO:0006094;nicotinamide nucleotide metabolic process#GO:0046496;ATP metabolic process#GO:0046034;aldehyde metabolic process#GO:0006081;metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;purine ribonucleotide metabolic process#GO:0009150;purine-containing compound catabolic process#GO:0072523;carbohydrate derivative biosynthetic process#GO:1901137;glucose metabolic process#GO:0006006;phosphorus metabolic process#GO:0006793;carboxylic acid metabolic process#GO:0019752;ribonucleoside diphosphate metabolic process#GO:0009185;small molecule metabolic process#GO:0044281;pyridine nucleotide catabolic process#GO:0019364;oxoacid metabolic process#GO:0043436;glyceraldehyde-3-phosphate metabolic process#GO:0019682;nucleobase-containing compound catabolic process#GO:0034655;ribonucleotide catabolic process#GO:0009261;carbohydrate derivative metabolic process#GO:1901135;nucleobase-containing compound metabolic process#GO:0006139;nucleotide catabolic process#GO:0009166;small molecule biosynthetic process#GO:0044283;energy derivation by oxidation of organic compounds#GO:0015980;hexose biosynthetic process#GO:0019319;purine ribonucleotide catabolic process#GO:0009154;nucleoside diphosphate catabolic process#GO:0009134;catabolic process#GO:0009056;carbohydrate metabolic process#GO:0005975;nucleoside phosphate metabolic process#GO:0006753;purine nucleotide catabolic process#GO:0006195;ribonucleoside diphosphate catabolic process#GO:0009191;organophosphate catabolic process#GO:0046434;cellular respiration#GO:0045333;organophosphate biosynthetic process#GO:0090407;cellular process#GO:0009987;ribose phosphate metabolic process#GO:0019693;carbohydrate biosynthetic process#GO:0016051;ADP catabolic process#GO:0046032;nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside diphosphate catabolic process#GO:0009137;monocarboxylic acid metabolic process#GO:0032787;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;pyridine-containing compound catabolic process#GO:0072526;pyruvate metabolic process#GO:0006090;ribonucleotide metabolic process#GO:0009259;purine nucleoside diphosphate metabolic process#GO:0009135;carbohydrate catabolic process#GO:0016052;nucleotide metabolic process#GO:0009117;organophosphate metabolic process#GO:0019637;glycolytic process#GO:0006096;purine ribonucleoside triphosphate metabolic process#GO:0009205;biosynthetic process#GO:0009058;monosaccharide biosynthetic process#GO:0046364;generation of precursor metabolites and energy#GO:0006091;purine ribonucleoside diphosphate metabolic process#GO:0009179;ADP metabolic process#GO:0046031;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;purine nucleoside triphosphate metabolic process#GO:0009144;nucleoside phosphate catabolic process#GO:1901292;nucleoside triphosphate metabolic process#GO:0009141;carbohydrate derivative catabolic process#GO:1901136;nucleoside diphosphate metabolic process#GO:0009132;pyridine-containing compound metabolic process#GO:0072524;purine ribonucleoside diphosphate catabolic process#GO:0009181;aerobic respiration#GO:0009060 isomerase#PC00135;metabolite interconversion enzyme#PC00262 Glycolysis#P00024>Triosephosphate isomerase#P00673 IXOSC|EnsemblGenome=LOC115330777|UniProtKB=A0ACM8F3P5 A0ACM8F3P5 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121835780|UniProtKB=A0ACM8FWK3 A0ACM8FWK3 LOC121835780 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032867|UniProtKB=A0ACM8EEC9 A0ACM8EEC9 LOC8032867 PTHR11571:SF222 GLUTATHIONE S-TRANSFERASE GLUTATHIONE S-TRANSFERASE MU 3 transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;glutathione transferase activity#GO:0004364;transferase activity#GO:0016740 glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 transferase#PC00220 IXOSC|EnsemblGenome=LOC8031782|UniProtKB=A0ACM8DVX8 A0ACM8DVX8 LOC8031782 PTHR13703:SF54 SMAD MOTHERS AGAINST DECAPENTAPLEGIC HOMOLOG double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;molecular function regulator activity#GO:0098772;sequence-specific double-stranded DNA binding#GO:1990837;molecular function inhibitor activity#GO:0140678;protein binding#GO:0005515;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565 cellular response to BMP stimulus#GO:0071773;cell surface receptor signaling pathway#GO:0007166;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;intracellular signaling cassette#GO:0141124;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to growth factor stimulus#GO:0071363;cellular response to endogenous stimulus#GO:0071495;cell differentiation#GO:0030154;response to stimulus#GO:0050896;regulation of transcription by RNA polymerase II#GO:0006357;signaling#GO:0023052;response to endogenous stimulus#GO:0009719;anatomical structure morphogenesis#GO:0009653;regulation of biological process#GO:0050789;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;response to BMP#GO:0071772;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cell communication#GO:0007154;regulation of DNA-templated transcription#GO:0006355;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;intracellular signal transduction#GO:0035556;regulation of RNA metabolic process#GO:0051252;response to growth factor#GO:0070848;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;BMP signaling pathway#GO:0030509;cellular response to stimulus#GO:0051716 RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227 gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 TGF-beta signaling pathway#P00052>RSmads#P01292 IXOSC|EnsemblGenome=LOC120850862|UniProtKB=A0ACM8FAW6 A0ACM8FAW6 LOC120850862 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120850173|UniProtKB=A0ACM8FL55 A0ACM8FL55 LOC120850173 PTHR14003:SF19 TRANSCRIPTIONAL REPRESSOR PROTEIN YY MISEXPRESSION SUPPRESSOR OF RAS 4, ISOFORM A sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977 regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 chromatin#GO:0000785;chromosome#GO:0005694;intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC115322947|UniProtKB=A0ACM8ES63 A0ACM8ES63 LOC115322947 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8038537|UniProtKB=A0ACM8DK46 A0ACM8DK46 PTHR12896:SF1 PAX6 NEIGHBOR PROTEIN PAXNEB ELONGATOR COMPLEX PROTEIN 4 tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033 catalytic complex#GO:1902494;cytoplasm#GO:0005737;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;elongator holoenzyme complex#GO:0033588;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC120841359|UniProtKB=A0ACM8ERL8 A0ACM8ERL8 LOC120841359 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8041808|UniProtKB=A0ACM8DUB6 A0ACM8DUB6 LOC8041808 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8032715|UniProtKB=A0ACM8DGL3 A0ACM8DGL3 LOC8032715 PTHR16007:SF15 EPIDIDYMAL MEMBRANE PROTEIN E9-RELATED TRANSMEMBRANE PROTEIN 45B-LIKE IXOSC|EnsemblGenome=LOC8034011|UniProtKB=A0ACM8EA32 A0ACM8EA32 Tom70 PTHR46208:SF1 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM70 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC8051134|UniProtKB=A0ACM8E5M7 A0ACM8E5M7 LOC8051134 PTHR48041:SF89 ABC TRANSPORTER G FAMILY MEMBER 28 FI03229P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 ATP-binding cassette (ABC) transporter#PC00003;transporter#PC00227;primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8050820|UniProtKB=A0ACM8E628 A0ACM8E628 LOC8050820 PTHR14744:SF15 N-ALPHA-ACETYLTRANSFERASE 60 N-ALPHA-ACETYLTRANSFERASE 60 acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;protein-N-terminal amino-acid acetyltransferase activity#GO:0004596;catalytic activity, acting on a protein#GO:0140096;protein N-acetyltransferase activity#GO:0034212;catalytic activity#GO:0003824;transferase activity#GO:0016740;histone modifying activity#GO:0140993;histone acetyltransferase activity#GO:0004402;protein N-acyltransferase activity#GO:0140186;N-acetyltransferase activity#GO:0008080;acyltransferase activity#GO:0016746;acetyltransferase activity#GO:0016407;protein-lysine-acetyltransferase activity#GO:0061733 cell cycle#GO:0007049;chromosome segregation#GO:0007059;cell cycle process#GO:0022402;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;Golgi membrane#GO:0000139;intracellular organelle#GO:0043229;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 transferase#PC00220;acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC8050642|UniProtKB=A0ACM8DRB5 A0ACM8DRB5 LOC8050642 PTHR46149:SF7 MIP08469P RAS-RELATED PROTEIN RAP-2A-LIKE IXOSC|EnsemblGenome=LOC8041113|UniProtKB=A0ACM8F5L3 A0ACM8F5L3 Rat1 PTHR12341:SF41 5'->3' EXORIBONUCLEASE 5'-3' EXORIBONUCLEASE 2 catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;RNA binding#GO:0003723;hydrolase activity#GO:0016787;5'-3' exonuclease activity#GO:0008409;nuclease activity#GO:0004518;nucleic acid binding#GO:0003676;binding#GO:0005488;exonuclease activity#GO:0004527 regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule biosynthetic process#GO:0010558;nucleobase-containing compound catabolic process#GO:0034655;mRNA catabolic process#GO:0006402;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 exoribonuclease#PC00099;RNA metabolism protein#PC00031 DNA replication#P00017>5' to 3' Exoribonulcease#P00535 IXOSC|EnsemblGenome=LOC8030069|UniProtKB=A0ACM8DJ69 A0ACM8DJ69 LOC8030069 PTHR48039:SF7 RNA-BINDING MOTIF PROTEIN 14B RNA-BINDING PROTEIN 28 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC8043154|UniProtKB=A0ACM8EC03 A0ACM8EC03 PTHR46314:SF2 SOLUTE CARRIER FAMILY 25 MEMBER 44 SOLUTE CARRIER FAMILY 25 MEMBER 44 carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;branched-chain amino acid transmembrane transporter activity#GO:0015658 branched-chain amino acid transport#GO:0015803;localization#GO:0051179;establishment of localization#GO:0051234;organic acid transport#GO:0015849;transport#GO:0006810;carboxylic acid transport#GO:0046942;nitrogen compound transport#GO:0071705 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8036135|UniProtKB=A0ACM8FHK0 A0ACM8FHK0 Snx27 PTHR12431:SF19 SORTING NEXIN 17 AND 27 SORTING NEXIN-27 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090 localization within membrane#GO:0051668;transport#GO:0006810;metabolic process#GO:0008152;intracellular transport#GO:0046907;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;macromolecule metabolic process#GO:0043170;localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;endocytic recycling#GO:0032456;vesicle-mediated transport#GO:0016192 intracellular organelle#GO:0043229;endosome#GO:0005768;early endosome#GO:0005769;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8039328|UniProtKB=A0ACM8E4V4 A0ACM8E4V4 LOC8039328 PTHR13091:SF0 AMPLIFIED IN BREAST CANCER 2-RELATED NONSENSE-MEDIATED MRNA DECAY FACTOR SMG8 catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;negative regulation of biological process#GO:0048519;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184 IXOSC|EnsemblGenome=LOC8024640|UniProtKB=A0ACM8E7R9 A0ACM8E7R9 LOC8024640 PTHR11008:SF9 PROTEIN TAKEOUT-LIKE PROTEIN FI04421P IXOSC|EnsemblGenome=LOC8041410|UniProtKB=A0ACM8FC46 A0ACM8FC46 LOC8041410 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC120841458|UniProtKB=A0ACM8ERM7 A0ACM8ERM7 LOC120841458 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120841568|UniProtKB=A0ACM8ERU2 A0ACM8ERU2 PTHR10578:SF149 S -2-HYDROXY-ACID OXIDASE-RELATED 2-HYDROXYACID OXIDASE 2 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614 biosynthetic process#GO:0009058;hydrogen peroxide metabolic process#GO:0042743;cellular process#GO:0009987;metabolic process#GO:0008152;reactive oxygen species metabolic process#GO:0072593 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;peroxisomal matrix#GO:0005782;microbody#GO:0042579;peroxisome#GO:0005777;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115326218|UniProtKB=A0ACM8E6D8 A0ACM8E6D8 LOC115326218 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120843432|UniProtKB=A0ACM8EVY2 A0ACM8EVY2 LOC120843432 PTHR24157:SF4 ANKYRIN REPEAT, SAM AND BASIC LEUCINE ZIPPER DOMAIN-CONTAINING PROTEIN 1 CELL PATTERN FORMATION-ASSOCIATED PROTEIN STUA IXOSC|EnsemblGenome=LOC121835178|UniProtKB=A0ACM8FRV5 A0ACM8FRV5 LOC121835178 PTHR42752:SF1 IMIDAZOLONEPROPIONASE IMIDAZOLONEPROPIONASE-RELATED catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides#GO:0016812;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;proteinogenic amino acid metabolic process#GO:0170039;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8024862|UniProtKB=A0ACM8FLD3 A0ACM8FLD3 PTHR45920:SF4 FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I FORMIN HOMOLOGY 2 DOMAIN CONTAINING, ISOFORM I protein-containing complex binding#GO:0044877;protein binding#GO:0005515;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;binding#GO:0005488 regulation of actin filament-based process#GO:0032970;cellular component organization or biogenesis#GO:0071840;positive regulation of actin filament bundle assembly#GO:0032233;actin filament organization#GO:0007015;organelle organization#GO:0006996;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;positive regulation of cellular component biogenesis#GO:0044089;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010;biological regulation#GO:0065007;actin filament-based process#GO:0030029;positive regulation of cellular component organization#GO:0051130;positive regulation of organelle organization#GO:0010638;supramolecular fiber organization#GO:0097435;cellular component organization#GO:0016043;regulation of actin filament bundle assembly#GO:0032231;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of cellular component biogenesis#GO:0044087;regulation of stress fiber assembly#GO:0051492 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8024092|UniProtKB=A0ACM8FRD9 A0ACM8FRD9 LOC8024092 PTHR10157:SF44 DOPAMINE BETA HYDROXYLASE RELATED TYRAMINE BETA-HYDROXYLASE oxidoreductase activity#GO:0016491;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705 multicellular organismal process#GO:0032501;response to chemical#GO:0042221;response to alcohol#GO:0097305;response to stimulus#GO:0050896;response to oxygen-containing compound#GO:1901700 membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;secretory granule membrane#GO:0030667;intracellular vesicle#GO:0097708;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;cytoplasm#GO:0005737;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;vesicle membrane#GO:0012506;membrane#GO:0016020;secretory vesicle#GO:0099503 hydroxylase#PC00122 Dopamine receptor mediated signaling pathway#P05912>DBH#P05955;Adrenaline and noradrenaline biosynthesis#P00001>DBH#P00063 IXOSC|EnsemblGenome=LOC8033052|UniProtKB=A0ACM8E5E3 A0ACM8E5E3 LOC8033052 PTHR24321:SF8 DEHYDROGENASES, SHORT CHAIN (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED metabolite interconversion enzyme#PC00262;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC121838130|UniProtKB=A0ACM8G6U8 A0ACM8G6U8 LOC121838130 PTHR43464:SF19 METHYLTRANSFERASE JUVENILE HORMONE ACID O-METHYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC121836643|UniProtKB=A0ACM8FZ02 A0ACM8FZ02 LOC121836643 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 ligase#PC00142 IXOSC|EnsemblGenome=LOC8023779|UniProtKB=A0ACM8DHJ6 A0ACM8DHJ6 mRpL44 PTHR11207:SF5 RIBONUCLEASE III LARGE RIBOSOMAL SUBUNIT PROTEIN ML44 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;RNA endonuclease activity#GO:0004521;catalytic activity, acting on RNA#GO:0140098;double-stranded RNA binding#GO:0003725;nucleic acid binding#GO:0003676;binding#GO:0005488;nuclease activity#GO:0004518;RNA binding#GO:0003723;hydrolase activity#GO:0016787 gene expression#GO:0010467;RNA processing#GO:0006396;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;primary miRNA processing#GO:0031053;metabolic process#GO:0008152;translational elongation#GO:0006414;nucleobase-containing compound biosynthetic process#GO:0034654;protein biosynthetic process#GO:0160307;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;miRNA processing#GO:0035196;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;regulatory ncRNA processing#GO:0070918;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;regulatory ncRNA-mediated gene silencing#GO:0031047;regulation of macromolecule metabolic process#GO:0060255;mitochondrial translation#GO:0032543;regulation of cellular process#GO:0050794;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;translation#GO:0006412 ribosome#GO:0005840;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;mitochondrial large ribosomal subunit#GO:0005762;membraneless organelle#GO:0043228 endoribonuclease#PC00094;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115317433|UniProtKB=A0ACM8DX57 A0ACM8DX57 LOC115317433 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8050753|UniProtKB=A0ACM8E3E1 A0ACM8E3E1 LOC8050753 PTHR12484:SF4 B-LYMPHOCYTE ANTIGEN-RELATED A-KINASE ANCHOR PROTEIN 17A IXOSC|EnsemblGenome=LOC8032552|UniProtKB=A0ACM8DSY1 A0ACM8DSY1 TBC1D23 PTHR13297:SF5 TBC1 DOMAIN FAMILY MEMBER 23-RELATED TBC1 DOMAIN FAMILY MEMBER 23 localization#GO:0051179;establishment of localization#GO:0051234;cellular localization#GO:0051641;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;trans-Golgi network#GO:0005802;Golgi apparatus subcompartment#GO:0098791;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115330486|UniProtKB=A0ACM8EGL8 A0ACM8EGL8 LOC115330486 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025284|UniProtKB=A0ACM8EFG1 A0ACM8EFG1 LOC8025284 PTHR24073:SF1242 DRAB5-RELATED RAS-RELATED PROTEIN RAB-18 hydrolase activity, acting on acid anhydrides#GO:0016817;pyrophosphatase activity#GO:0016462;GTPase activity#GO:0003924;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ribonucleoside triphosphate phosphatase activity#GO:0017111;hydrolase activity#GO:0016787 lipid droplet organization#GO:0034389;localization#GO:0051179;cellular localization#GO:0051641;protein transport#GO:0015031;cellular component organization#GO:0016043;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;cellular component organization or biogenesis#GO:0071840;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036;organelle organization#GO:0006996;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 G-protein#PC00020;small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120848657|UniProtKB=A0ACM8F756 A0ACM8F756 LOC120848657 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120839164|UniProtKB=A0ACM8EMH4 A0ACM8EMH4 LOC120839164 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842622|UniProtKB=A0ACM8G5I4 A0ACM8G5I4 LOC120842622 PTHR16515:SF87 PR DOMAIN ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8033293|UniProtKB=A0ACM8E8Q6 A0ACM8E8Q6 Nprl2 PTHR12991:SF10 NITROGEN PERMEASE REGULATOR 2/TUMOR SUPPRESSOR CANDIDATE 4 GATOR1 COMPLEX PROTEIN NPRL2 GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme activator activity#GO:0008047 regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;negative regulation of TOR signaling#GO:0032007;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to starvation#GO:0042594;negative regulation of biological process#GO:0048519;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of signaling#GO:0023051;cellular response to stress#GO:0033554;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of response to stimulus#GO:0048585;cellular response to amino acid starvation#GO:0034198;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;response to stress#GO:0006950;response to nutrient levels#GO:0031667;regulation of TORC1 signaling#GO:1903432;regulation of response to stimulus#GO:0048583;negative regulation of TORC1 signaling#GO:1904262;cellular response to nutrient levels#GO:0031669;negative regulation of cellular process#GO:0048523;cellular response to starvation#GO:0009267 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;vacuole#GO:0005773;membrane#GO:0016020;vacuolar membrane#GO:0005774;Seh1-associated complex#GO:0035859;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;bounding membrane of organelle#GO:0098588;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 GTPase-activating protein#PC00257;G-protein modulator#PC00022 IXOSC|EnsemblGenome=LOC120848618|UniProtKB=A0ACM8F593 A0ACM8F593 LOC120848618 PTHR46888:SF18 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026580|UniProtKB=A0ACM8DSE9 A0ACM8DSE9 LOC8026580 PTHR24264:SF65 TRYPSIN-RELATED DUF7495 DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8038479|UniProtKB=A0ACM8DK42 A0ACM8DK42 LOC8038479 PTHR44653:SF2 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 DNAJ HOMOLOG SUBFAMILY C MEMBER 1 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8028955|UniProtKB=A0ACM8F2Z7 A0ACM8F2Z7 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC8024364|UniProtKB=A0ACM8ECX0 A0ACM8ECX0 RIOK2 PTHR45852:SF1 SER/THR-PROTEIN KINASE RIO2 SERINE_THREONINE-PROTEIN KINASE RIO2 transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;phosphotransferase activity, alcohol group as acceptor#GO:0016773;catalytic activity, acting on a protein#GO:0140096;protein kinase activity#GO:0004672 cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;ribosomal small subunit biogenesis#GO:0042274;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;preribosome#GO:0030684;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;cytosol#GO:0005829 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8052730|UniProtKB=A0ACM8DYB1 A0ACM8DYB1 LOC8052730 PTHR10219:SF43 GLYCOLIPID TRANSFER PROTEIN-RELATED GLYCOLIPID TRANSFER PROTEIN DOMAIN-CONTAINING PROTEIN phospholipid binding#GO:0005543;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;ion binding#GO:0043167;lipid carrier activity#GO:0005319;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168;phospholipid transfer activity#GO:0120014;lipid binding#GO:0008289;lipid transfer activity#GO:0120013 membrane organization#GO:0061024;ceramide transport#GO:0035627;lipid transport#GO:0006869;cellular process#GO:0009987;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;localization#GO:0051179;intermembrane lipid transfer#GO:0120009;establishment of localization#GO:0051234;transport#GO:0006810;lipid localization#GO:0010876 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;membrane#GO:0016020;cytosol#GO:0005829 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8028473|UniProtKB=A0ACM8DRZ2 A0ACM8DRZ2 LOC8028473 PTHR43981:SF2 ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;small molecule metabolic process#GO:0044281;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739 reductase#PC00198;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8023365|UniProtKB=A0ACM8DGV5 A0ACM8DGV5 LOC8023365 PTHR11211:SF49 IROQUOIS-CLASS HOMEODOMAIN PROTEIN IRX MIRROR, ISOFORM C transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;neurogenesis#GO:0022008;developmental process#GO:0032502;neuron differentiation#GO:0030182;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;cell development#GO:0048468;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8037356|UniProtKB=A0ACM8FB17 A0ACM8FB17 LOC8037356 PTHR12963:SF4 THYROID RECEPTOR INTERACTING PROTEIN RELATED TRIP4_RQT4 C2HC5-TYPE ZINC FINGER DOMAIN-CONTAINING PROTEIN macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;translational elongation#GO:0006414;metabolic process#GO:0008152;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;organelle organization#GO:0006996;proteasomal protein catabolic process#GO:0010498;biosynthetic process#GO:0009058;gene expression#GO:0010467;modification-dependent macromolecule catabolic process#GO:0043632;translation#GO:0006412;protein catabolic process#GO:0030163;cellular component disassembly#GO:0022411;protein metabolic process#GO:0019538;organelle disassembly#GO:1903008;rescue of stalled cytosolic ribosome#GO:0072344;modification-dependent protein catabolic process#GO:0019941;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;protein biosynthetic process#GO:0160307;cytoplasmic translation#GO:0002181;catabolic process#GO:0009056 protein-containing complex#GO:0032991 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC120844211|UniProtKB=A0ACM8EZ76 A0ACM8EZ76 LOC120844211 PTHR33198:SF24 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034556|UniProtKB=A0ACM8DZS5 A0ACM8DZS5 PTHR12326:SF3 PLECKSTRIN HOMOLOGY DOMAIN CONTAINING PROTEIN DIFFERENTIALLY EXPRESSED IN FDCP 8 HOMOLOG IXOSC|EnsemblGenome=LOC115332525|UniProtKB=A0ACM8EDT2 A0ACM8EDT2 LOC115332525 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8050755|UniProtKB=A0ACM8E437 A0ACM8E437 plx PTHR47219:SF16 RAB GTPASE-ACTIVATING PROTEIN 1-LIKE TBC1 DOMAIN FAMILY MEMBER-RELATED GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;nucleoside-triphosphatase regulator activity#GO:0060589;molecular function regulator activity#GO:0098772;enzyme activator activity#GO:0008047;protein binding#GO:0005515;enzyme regulator activity#GO:0030234;small GTPase binding#GO:0031267;molecular function activator activity#GO:0140677;binding#GO:0005488;enzyme binding#GO:0019899 G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC121048331|UniProtKB=A0ACM8FI47 A0ACM8FI47 LOC121048331 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC115321488|UniProtKB=A0ACM8E185 A0ACM8E185 LOC115321488 PTHR33244:SF3 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120836000|UniProtKB=A0ACM8EJD4 A0ACM8EJD4 LOC120836000 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;binding#GO:0005488;catalytic activity#GO:0003824;small molecule binding#GO:0036094;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058;fatty acid biosynthetic process#GO:0006633 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115317364|UniProtKB=A0ACM8FXS0 A0ACM8FXS0 LOC115317364 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC120845774|UniProtKB=A0ACM8F0J7 A0ACM8F0J7 LOC120845774 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8026345|UniProtKB=A0ACM8EHH5 A0ACM8EHH5 LOC8026345 PTHR43903:SF12 NEUROLIGIN CARBOXYLESTERASE TYPE B DOMAIN-CONTAINING PROTEIN apical junction complex#GO:0043296;cell-cell junction#GO:0005911;cell junction#GO:0030054;tight junction#GO:0070160;cellular anatomical structure#GO:0110165;anchoring junction#GO:0070161 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8043660|UniProtKB=A0ACM8FEP2 A0ACM8FEP2 Bili PTHR13283:SF10 KREV INTERACTION TRAPPED 1-RELATED FERM DOMAIN-CONTAINING PROTEIN 8 negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;negative regulation of signal transduction#GO:0009968;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of canonical Wnt signaling pathway#GO:0060828;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;regulation of cellular process#GO:0050794;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;negative regulation of canonical Wnt signaling pathway#GO:0090090;regulation of signaling#GO:0023051 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8042391|UniProtKB=A0ACM8DXF1 A0ACM8DXF1 LOC8042391 PTHR45796:SF4 FORKHEAD BOX P, ISOFORM C FORKHEAD BOX P, ISOFORM C sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 winged helix/forkhead transcription factor#PC00246;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC8028871|UniProtKB=A0ACM8FWF3 A0ACM8FWF3 LOC8028871 PTHR11806:SF4 GLUCOSE INHIBITED DIVISION PROTEIN A 5-TAURINOMETHYLURIDINE-[TRNA] SYNTHASE SUBUNIT MTO1, MITOCHONDRIAL catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;mitochondrial RNA metabolic process#GO:0000959;mitochondrial gene expression#GO:0140053;mitochondrial RNA modification#GO:1900864;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;cellular process#GO:0009987;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 intracellular organelle#GO:0043229;transferase complex#GO:1990234;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC8026164|UniProtKB=A0ACM8ENT6 A0ACM8ENT6 LOC8026164 PTHR24369:SF222 ANTIGEN BSP, PUTATIVE-RELATED SUBFAMILY NOT NAMED cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8040289|UniProtKB=A0ACM8E744 A0ACM8E744 LOC8040289 PTHR10663:SF402 GUANYL-NUCLEOTIDE EXCHANGE FACTOR MIP16918P plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 guanyl-nucleotide exchange factor#PC00113 IXOSC|EnsemblGenome=LOC121836997|UniProtKB=A0ACM8G242 A0ACM8G242 LOC121836997 PTHR47577:SF4 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328814|UniProtKB=A0ACM8EHB1 A0ACM8EHB1 LOC115328814 PTHR14196:SF16 ODD-SKIPPED - RELATED ZINC FINGER PROTEIN 208-LIKE zinc finger transcription factor#PC00244;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8033479|UniProtKB=A0ACM8FMX9 A0ACM8FMX9 PTHR24082:SF283 NUCLEAR HORMONE RECEPTOR NUCLEAR HORMONE RECEPTOR HR96 signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976 positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;positive regulation of biosynthetic process#GO:0009891;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;positive regulation of RNA biosynthetic process#GO:1902680;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622 C4 zinc finger nuclear receptor#PC00169 IXOSC|EnsemblGenome=LOC115324980|UniProtKB=A0ACM8EXT6 A0ACM8EXT6 LOC115324980 PTHR37162:SF13 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031810|UniProtKB=A0ACM8DVU6 A0ACM8DVU6 LOC8031810 PTHR15045:SF1 FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE FUCOSE-1-PHOSPHATE GUANYLYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;nucleotidyltransferase activity#GO:0016779;transferase activity, transferring phosphorus-containing groups#GO:0016772 phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;organophosphate biosynthetic process#GO:0090407;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;nucleotide-sugar metabolic process#GO:0009225;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086 transferase#PC00220 IXOSC|EnsemblGenome=LOC115326317|UniProtKB=A0ACM8E5V7 A0ACM8E5V7 LOC115326317 PTHR24083:SF54 NUCLEAR HORMONE RECEPTOR NUCLEAR HORMONE RECEPTOR HR78 signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;nuclear receptor activity#GO:0004879;DNA binding#GO:0003677;molecular transducer activity#GO:0060089;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169 IXOSC|EnsemblGenome=LOC8023199|UniProtKB=A0ACM8DQD9 A0ACM8DQD9 LOC8023199 PTHR13140:SF561 MYOSIN MIP31562P1 polypeptide conformation or assembly isomerase activity#GO:0120544;catalytic activity#GO:0003824;microfilament motor activity#GO:0000146;macromolecular conformation isomerase activity#GO:0120543;ATP-dependent activity#GO:0140657;cytoskeletal motor activity#GO:0003774;isomerase activity#GO:0016853 actin filament-based process#GO:0030029;cellular component organization or biogenesis#GO:0071840;actin filament organization#GO:0007015;supramolecular fiber organization#GO:0097435;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cytoskeleton organization#GO:0007010 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;actin cytoskeleton#GO:0015629;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 actin binding motor protein#PC00040 IXOSC|EnsemblGenome=LOC115328429|UniProtKB=A0ACM8ERB5 A0ACM8ERB5 LOC115328429 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxygenase#PC00177;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120846080|UniProtKB=A0ACM8F196 A0ACM8F196 LOC120846080 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;telomere maintenance#GO:0000723;chromosome organization#GO:0051276;telomere organization#GO:0032200;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;organelle organization#GO:0006996;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC115330194|UniProtKB=A0ACM8EBV7 A0ACM8EBV7 LOC115330194 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120847667|UniProtKB=A0ACM8F4M4 A0ACM8F4M4 LOC120847667 PTHR11426:SF281 HISTONE H3 HISTONE H3 cell cycle#GO:0007049;sister chromatid segregation#GO:0000819;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;nuclear chromosome segregation#GO:0098813;mitotic metaphase chromosome alignment#GO:0007080;protein-containing complex assembly#GO:0065003;cell cycle process#GO:0022402;mitotic nuclear division#GO:0140014;mitotic cell cycle#GO:0000278;organelle assembly#GO:0070925;organelle localization#GO:0051640;nuclear division#GO:0000280;kinetochore assembly#GO:0051382;localization#GO:0051179;kinetochore organization#GO:0051383;organelle fission#GO:0048285;organelle organization#GO:0006996;mitotic sister chromatid segregation#GO:0000070;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;chromosome localization#GO:0050000;metaphase chromosome alignment#GO:0051310;chromosome segregation#GO:0007059;cellular component organization or biogenesis#GO:0071840;mitotic cell cycle process#GO:1903047;chromosome organization#GO:0051276;protein-containing complex organization#GO:0043933 chromatin/chromatin-binding, or -regulatory protein#PC00077 DNA replication#P00017>Histones#P00527 IXOSC|EnsemblGenome=LOC115314802|UniProtKB=A0ACM8EWA3 A0ACM8EWA3 LOC115314802 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC115327261|UniProtKB=A0ACM8G467 A0ACM8G467 LOC115327261 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC121834793|UniProtKB=A0ACM8FR51 A0ACM8FR51 LOC121834793 PTHR19446:SF488 REVERSE TRANSCRIPTASES REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120846301|UniProtKB=A0ACM8FZA8 A0ACM8FZA8 LOC120846301 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115309339|UniProtKB=A0ACM8F663 A0ACM8F663 LOC115309339 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8051713|UniProtKB=A0ACM8EA14 A0ACM8EA14 LOC8051713 PTHR24252:SF37 ACROSIN-RELATED SUBFAMILY NOT NAMED serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8043055|UniProtKB=A0ACM8E7Y3 A0ACM8E7Y3 LOC8043055 PTHR24149:SF14 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12 intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8029029|UniProtKB=A0ACM8E1K7 A0ACM8E1K7 LOC8029029 PTHR24351:SF209 RIBOSOMAL PROTEIN S6 KINASE NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;protein serine/threonine kinase activity#GO:0004674;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672 response to oxygen-containing compound#GO:1901700;response to endogenous stimulus#GO:0009719;response to hormone#GO:0009725;response to nitrogen compound#GO:1901698;response to peptide hormone#GO:0043434;response to chemical#GO:0042221;response to stimulus#GO:0050896 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115325650|UniProtKB=A0ACM8F962 A0ACM8F962 LOC115325650 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 small molecule biosynthetic process#GO:0044283;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;biosynthetic process#GO:0009058;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281 reductase#PC00198 IXOSC|EnsemblGenome=LOC120841186|UniProtKB=A0ACM8EQR9 A0ACM8EQR9 LOC120841186 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120850058|UniProtKB=A0ACM8FSD2 A0ACM8FSD2 Gbeta5 PTHR19850:SF36 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-5 signaling receptor complex adaptor activity#GO:0030159;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;signaling adaptor activity#GO:0035591 G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;cell communication#GO:0007154;response to nitrogen compound#GO:1901698;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;G protein-coupled dopamine receptor signaling pathway#GO:0007212;cellular response to oxygen-containing compound#GO:1901701;signal transduction#GO:0007165;cellular process#GO:0009987;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007 cytoplasm#GO:0005737;plasma membrane#GO:0005886;protein-containing complex#GO:0032991;cell periphery#GO:0071944;membrane#GO:0016020;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;intracellular anatomical structure#GO:0005622;side of membrane#GO:0098552;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494 heterotrimeric G-protein#PC00117;G-protein#PC00020;protein-binding activity modulator#PC00095 Beta3 adrenergic receptor signaling pathway#P04379>G-Protein#P04448;Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Gbeta5L#P00748;Beta1 adrenergic receptor signaling pathway#P04377>G-Protein#P04436;Opioid prodynorphin pathway#P05916>G-protein#P06002;Metabotropic glutamate receptor group II pathway#P00040>G-protein#P01047;Histamine H2 receptor mediated signaling pathway#P04386>G-Protein#P04490;Beta2 adrenergic receptor signaling pathway#P04378>G-Protein#P04443;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Opioid proenkephalin pathway#P05915>G-protein#P05994;5HT1 type receptor mediated signaling pathway#P04373>G-protein#P04408;PI3 kinase pathway#P00048>Gbetagamma#P01188;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Enkephalin release#P05913>G-Protein (i)#P05974;Enkephalin release#P05913>G-Protein (s)#P05977;Gonadotropin-releasing hormone receptor pathway#P06664>Gbeta#P06769;5HT4 type receptor mediated signaling pathway#P04376>G-protein#P04430;Metabotropic glutamate receptor group III pathway#P00039>G-Protein#P01045;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Opioid proopiomelanocortin pathway#P05917>G-protein#P06012;Angiotensin II-stimulated signaling through G proteins and beta-arrestin#P05911>Gbeta#P05930;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>G-Protein#P01085 IXOSC|EnsemblGenome=LOC120841232|UniProtKB=A0ACM8ES87 A0ACM8ES87 LOC120841232 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115318776|UniProtKB=A0ACM8FKF9 A0ACM8FKF9 LOC115318776 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8051991|UniProtKB=A0ACM8FBM4 A0ACM8FBM4 PTHR45889:SF2 IG-LIKE DOMAIN-CONTAINING PROTEIN CELL ADHESION MOLECULE 1 protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488 positive regulation of immune effector process#GO:0002699;biological regulation#GO:0065007;positive regulation of response to stimulus#GO:0048584;regulation of natural killer cell mediated cytotoxicity#GO:0042269;positive regulation of innate immune response#GO:0045089;positive regulation of cellular process#GO:0048522;positive regulation of natural killer cell mediated cytotoxicity#GO:0045954;detection of stimulus#GO:0051606;homophilic cell-cell adhesion#GO:0007156;positive regulation of response to biotic stimulus#GO:0002833;regulation of innate immune response#GO:0045088;regulation of response to stimulus#GO:0048583;positive regulation of defense response#GO:0031349;positive regulation of immune response#GO:0050778;regulation of response to stress#GO:0080134;positive regulation of leukocyte mediated immunity#GO:0002705;regulation of response to biotic stimulus#GO:0002831;positive regulation of natural killer cell mediated immunity#GO:0002717;regulation of cellular process#GO:0050794;regulation of immune system process#GO:0002682;regulation of natural killer cell mediated immunity#GO:0002715;regulation of leukocyte mediated immunity#GO:0002703;regulation of leukocyte mediated cytotoxicity#GO:0001910;regulation of immune effector process#GO:0002697;positive regulation of lymphocyte mediated immunity#GO:0002708;cell recognition#GO:0008037;regulation of defense response#GO:0031347;regulation of immune response#GO:0050776;regulation of response to external stimulus#GO:0032101;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of immune system process#GO:0002684;cell-cell adhesion#GO:0098609;positive regulation of response to external stimulus#GO:0032103;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;regulation of cell killing#GO:0031341;cell adhesion#GO:0007155;regulation of lymphocyte mediated immunity#GO:0002706 membrane#GO:0016020;cell periphery#GO:0071944;neuron projection#GO:0043005;synapse#GO:0045202;cellular anatomical structure#GO:0110165;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;plasma membrane#GO:0005886;cell junction#GO:0030054 IXOSC|EnsemblGenome=LOC115326954|UniProtKB=A0ACM8G1P6 A0ACM8G1P6 LOC115326954 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252 metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC8039702|UniProtKB=A0ACM8DKF7 A0ACM8DKF7 LOC8039702 PTHR23199:SF19 NEUROTROPHIN 1-RELATED SPAETZLE DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546;growth factor activity#GO:0008083;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function activator activity#GO:0140677;protein binding#GO:0005515;binding#GO:0005488;signaling receptor binding#GO:0005102 immune system process#GO:0002376;animal gross anatomical part developmental process#GO:0160108;anatomical structure development#GO:0048856;system development#GO:0048731;anatomical structure morphogenesis#GO:0009653;response to stimulus#GO:0050896;central nervous system development#GO:0007417;biological process involved in interspecies interaction between organisms#GO:0044419;response to external biotic stimulus#GO:0043207;developmental process#GO:0032502;multicellular organism development#GO:0007275;innate immune response#GO:0045087;response to external stimulus#GO:0009605;anatomical structure formation involved in morphogenesis#GO:0048646;defense response#GO:0006952;response to biotic stimulus#GO:0009607;response to stress#GO:0006950;defense response to symbiont#GO:0140546;immune response#GO:0006955;multicellular organismal process#GO:0032501;defense response to other organism#GO:0098542;response to other organism#GO:0051707;nervous system development#GO:0007399 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC115327457|UniProtKB=A0ACM8G795 A0ACM8G795 LOC115327457 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D nervous system development#GO:0007399;cell differentiation#GO:0030154;multicellular organismal process#GO:0032501;cellular process#GO:0009987;system development#GO:0048731;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;cellular developmental process#GO:0048869;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121836612|UniProtKB=A0ACM8G0M9 A0ACM8G0M9 LOC121836612 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115313491|UniProtKB=A0ACM8EVD4 A0ACM8EVD4 LOC115313491 PTHR46609:SF11 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8036394|UniProtKB=A0ACM8EDI6 A0ACM8EDI6 Rpp30 PTHR13031:SF0 RIBONUCLEASE P SUBUNIT P30 RIBONUCLEASE P PROTEIN SUBUNIT P30 RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676 RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;gene expression#GO:0010467;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;endonuclease complex#GO:1905348;nucleolar ribonuclease P complex#GO:0005655;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;multimeric ribonuclease P complex#GO:0030681;organelle lumen#GO:0043233;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;ribonucleoprotein complex#GO:1990904;ribonuclease P complex#GO:0030677;endoribonuclease complex#GO:1902555 endoribonuclease#PC00094;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8025615|UniProtKB=A0ACM8DT79 A0ACM8DT79 PTHR22760:SF4 GLYCOSYLTRANSFERASE GPI ALPHA-1,2-MANNOSYLTRANSFERASE 3 mannosyltransferase activity#GO:0000030;glycosyltransferase activity#GO:0016757;hexosyltransferase activity#GO:0016758;transferase activity#GO:0016740;catalytic activity#GO:0003824 metabolic process#GO:0008152;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;protein maturation#GO:0051604;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;biosynthetic process#GO:0009058;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;phospholipid metabolic process#GO:0006644 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8039159|UniProtKB=A0ACM8FGF8 A0ACM8FGF8 LOC8039159 PTHR18966:SF575 IONOTROPIC GLUTAMATE RECEPTOR CLUMSY, ISOFORM B-RELATED transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential#GO:1904315;glutamate receptor activity#GO:0008066;passive transmembrane transporter activity#GO:0022803;ligand-gated channel activity#GO:0022834;transmembrane transporter activity#GO:0022857;molecular transducer activity#GO:0060089;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;extracellular ligand-gated monoatomic ion channel activity#GO:0005230;signaling receptor activity#GO:0038023;neurotransmitter receptor activity#GO:0030594;transporter activity#GO:0005215;gated channel activity#GO:0022836;transmembrane signaling receptor activity#GO:0004888 synaptic signaling#GO:0099536;cellular process#GO:0009987;regulation of trans-synaptic signaling#GO:0099177;synaptic transmission, glutamatergic#GO:0035249;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;trans-synaptic signaling#GO:0099537;regulation of signaling#GO:0023051;cell communication#GO:0007154;chemical synaptic transmission#GO:0007268;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;anterograde trans-synaptic signaling#GO:0098916;regulation of cell communication#GO:0010646;modulation of chemical synaptic transmission#GO:0050804;signaling#GO:0023052 postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density#GO:0014069;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;asymmetric synapse#GO:0032279;organelle#GO:0043226;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;cell junction#GO:0030054;membrane#GO:0016020;cell periphery#GO:0071944;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 Ionotropic glutamate receptor pathway#P00037>AMPA#P01019;Ionotropic glutamate receptor pathway#P00037>A/K#P01025 IXOSC|EnsemblGenome=LOC8042925|UniProtKB=A0ACM8DMX2 A0ACM8DMX2 LOC8042925 PTHR46591:SF1 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26 ZINC FINGER FYVE DOMAIN-CONTAINING PROTEIN 26 phospholipid binding#GO:0005543;binding#GO:0005488;phosphatidylinositol phosphate binding#GO:1901981;lipid binding#GO:0008289;phosphatidylinositol-3-phosphate binding#GO:0032266 regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of cell cycle process#GO:0010564;regulation of cell cycle#GO:0051726;regulation of cytokinesis#GO:0032465;regulation of cell division#GO:0051302;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;microtubule cytoskeleton#GO:0015630;midbody#GO:0030496;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;microtubule organizing center#GO:0005815;centrosome#GO:0005813;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC121834427|UniProtKB=A0ACM8FQ74 A0ACM8FQ74 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120839930|UniProtKB=A0ACM8EN21 A0ACM8EN21 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032402|UniProtKB=A0ACM8DQB6 A0ACM8DQB6 LOC8032402 PTHR12496:SF2 CGI-41 METHYLTRANSFERASE METHYLTRANSFERASE-LIKE PROTEIN 25B RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8030089|UniProtKB=A0ACM8FVR1 A0ACM8FVR1 LOC8030089 PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310;transporter activity#GO:0005215;carboxylic acid transmembrane transporter activity#GO:0046943;transmembrane transporter activity#GO:0022857;citrate transmembrane transporter activity#GO:0015137;C4-dicarboxylate transmembrane transporter activity#GO:0015556 tricarboxylic acid transport#GO:0006842;carboxylic acid transport#GO:0046942;C4-dicarboxylate transport#GO:0015740;transport#GO:0006810;organic acid transport#GO:0015849;citrate transport#GO:0015746;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC120840186|UniProtKB=A0ACM8ENV0 A0ACM8ENV0 LOC120840186 PTHR11588:SF501 TUBULIN TUBULIN ALPHA CHAIN nucleotide binding#GO:0000166;structural molecule activity#GO:0005198;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine ribonucleoside triphosphate binding#GO:0035639;purine nucleotide binding#GO:0017076;purine ribonucleotide binding#GO:0032555;heterocyclic compound binding#GO:1901363;guanyl nucleotide binding#GO:0019001;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200;guanyl ribonucleotide binding#GO:0032561;GTP binding#GO:0005525 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;microtubule-based process#GO:0007017;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;organelle organization#GO:0006996;cell cycle#GO:0007049;cellular component organization#GO:0016043;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;supramolecular complex#GO:0099080;organelle#GO:0043226;cellular anatomical structure#GO:0110165;supramolecular polymer#GO:0099081;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229;microtubule#GO:0005874;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 tubulin#PC00228;cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120837073|UniProtKB=A0ACM8FIH7 A0ACM8FIH7 LOC120837073 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051407|UniProtKB=A0ACM8FTR3 A0ACM8FTR3 LOC8051407 PTHR32470:SF2 ADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 2 protein-containing complex organization#GO:0043933;NADH dehydrogenase complex assembly#GO:0010257;cellular component organization or biogenesis#GO:0071840;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component assembly#GO:0022607;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;mitochondrial respiratory chain complex I assembly#GO:0032981;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8034055|UniProtKB=A0ACM8DS25 A0ACM8DS25 LOC8034055 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 gene-specific transcriptional regulator#PC00264;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC120850692|UniProtKB=A0ACM8FAM5 A0ACM8FAM5 LOC120850692 PTHR11439:SF463 GAG-POL-RELATED RETROTRANSPOSON INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN-RELATED viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8038764|UniProtKB=A0ACM8DNH1 A0ACM8DNH1 LOC8038764 PTHR23089:SF55 HISTIDINE TRIAD HIT PROTEIN ADENOSINE 5'-MONOPHOSPHORAMIDASE HINT1 catalytic activity#GO:0003824;hydrolase activity#GO:0016787 organophosphate catabolic process#GO:0046434;nucleotide metabolic process#GO:0009117;ribonucleotide metabolic process#GO:0009259;purine nucleotide catabolic process#GO:0006195;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;nucleoside phosphate catabolic process#GO:1901292;carbohydrate derivative catabolic process#GO:1901136;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine ribonucleotide catabolic process#GO:0009154;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;purine-containing compound catabolic process#GO:0072523;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;nucleotide catabolic process#GO:0009166;purine ribonucleotide metabolic process#GO:0009150;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;nucleobase-containing compound catabolic process#GO:0034655;carbohydrate derivative metabolic process#GO:1901135;ribonucleotide catabolic process#GO:0009261;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 nucleotide phosphatase#PC00173 IXOSC|EnsemblGenome=LOC115327290|UniProtKB=A0ACM8EKW1 A0ACM8EKW1 LOC115327290 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 localization#GO:0051179;localization within membrane#GO:0051668;organelle localization#GO:0051640;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;nuclear migration#GO:0007097;heterochromatin formation#GO:0031507;nuclear envelope organization#GO:0006998;regulation of gene expression#GO:0010468;intracellular protein localization#GO:0008104;nucleus organization#GO:0006997;establishment of localization#GO:0051234;regulation of biosynthetic process#GO:0009889;transport#GO:0006810;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;membrane organization#GO:0061024;negative regulation of macromolecule metabolic process#GO:0010605;protein localization to nucleus#GO:0034504;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;macromolecule localization#GO:0033036;cellular localization#GO:0051641;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;establishment of organelle localization#GO:0051656;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;heterochromatin organization#GO:0070828;endomembrane system organization#GO:0010256;cellular component assembly#GO:0022607;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;negative regulation of macromolecule biosynthetic process#GO:0010558 intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635;nuclear lumen#GO:0031981;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;organelle envelope#GO:0031967;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC8044055|UniProtKB=A0ACM8DN12 A0ACM8DN12 LOC8044055 PTHR21467:SF0 PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 PPP4R4 SERINE_THREONINE-PROTEIN PHOSPHATASE 4 REGULATORY SUBUNIT 4 enzyme regulator activity#GO:0030234;phosphatase regulator activity#GO:0019208;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888 protein serine/threonine phosphatase complex#GO:0008287;catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC120847733|UniProtKB=A0ACM8F4F8 A0ACM8F4F8 LOC120847733 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8026895|UniProtKB=A0ACM8E0M9 A0ACM8E0M9 PTHR24379:SF127 KRAB AND ZINC FINGER DOMAIN-CONTAINING IP01257P-RELATED DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8036926|UniProtKB=A0ACM8E407 A0ACM8E407 LOC8036926 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC8023819|UniProtKB=A0ACM8DYL9 A0ACM8DYL9 LOC8023819 PTHR31158:SF10 DUAL OXIDASE 2 LD27791P membrane#GO:0016020;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxidase#PC00175 IXOSC|EnsemblGenome=LOC8043708|UniProtKB=A0ACM8E9T4 A0ACM8E9T4 LOC8043708 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8039788|UniProtKB=A0ACM8FUT5 A0ACM8FUT5 LOC8039788 PTHR43580:SF10 OXIDOREDUCTASE GLYR1-RELATED CYTOKINE-LIKE NUCLEAR FACTOR N-PAC DNA binding#GO:0003677;protein-containing complex binding#GO:0044877;nucleosome binding#GO:0031491;nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682 DNA-templated transcription elongation#GO:0006354;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;chromatin organization#GO:0006325;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;transcription by RNA polymerase II#GO:0006366;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;RNA biosynthetic process#GO:0032774;chromatin remodeling#GO:0006338;DNA-templated transcription#GO:0006351;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070 intracellular membraneless organelle#GO:0043232;organelle#GO:0043226;cellular anatomical structure#GO:0110165;chromatin#GO:0000785;chromosome#GO:0005694;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120841180|UniProtKB=A0ACM8EQR4 A0ACM8EQR4 LOC120841180 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;catalytic activity#GO:0003824;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8030342|UniProtKB=A0ACM8DGS9 A0ACM8DGS9 Mlh1 PTHR10073:SF59 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL MLH1, ISOFORM A catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;DNA nuclease activity#GO:0004536;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520;nuclease activity#GO:0004518;endonuclease activity#GO:0004519 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;response to stress#GO:0006950;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;DNA repair#GO:0006281;metabolic process#GO:0008152;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8038671|UniProtKB=A0ACM8E0F7 A0ACM8E0F7 LOC8038671 PTHR13989:SF16 REPLICATION PROTEIN A-RELATED REPLICATION FACTOR A PROTEIN 2 sequence-specific DNA binding#GO:0043565;telomeric repeat DNA binding#GO:0042162;DNA binding#GO:0003677;single-stranded DNA binding#GO:0003697;nucleic acid binding#GO:0003676;binding#GO:0005488 cellular response to stress#GO:0033554;recombinational repair#GO:0000725;cellular response to stimulus#GO:0051716;DNA replication#GO:0006260;double-strand break repair via homologous recombination#GO:0000724;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;response to stimulus#GO:0050896;DNA damage response#GO:0006974;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;double-strand break repair#GO:0006302;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;response to stress#GO:0006950;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139 protein-containing complex#GO:0032991;chromosome, telomeric region#GO:0000781;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;site of double-strand break#GO:0035861;nucleus#GO:0005634;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;replication fork#GO:0005657;replisome#GO:0030894;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;site of DNA damage#GO:0090734;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229 DNA replication#P00017>RPA#P00537 IXOSC|EnsemblGenome=LOC120843155|UniProtKB=A0ACM8EVE8 A0ACM8EVE8 LOC120843155 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121833035|UniProtKB=A0ACM8FHX6 A0ACM8FHX6 LOC121833035 PTHR45702:SF2 ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER ADAM10 ENDOPEPTIDASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 membrane protein ectodomain proteolysis#GO:0006509;primary metabolic process#GO:0044238;cellular process#GO:0009987;membrane protein proteolysis#GO:0033619;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;protein modifying enzyme#PC00260 Alzheimer disease-amyloid secretase pathway#P00003>ADAM10#P00108 IXOSC|EnsemblGenome=LOC115318277|UniProtKB=A0ACM8EWW1 A0ACM8EWW1 PTHR23324:SF91 SEC14 RELATED PROTEIN RE68566P cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8029781|UniProtKB=A0ACM8DIU0 A0ACM8DIU0 LOC8029781 PTHR24413:SF240 SPECKLE-TYPE POZ PROTEIN PROTEIN ROADKILL binding#GO:0005488;ubiquitin-like protein ligase binding#GO:0044389;enzyme binding#GO:0019899;protein binding#GO:0005515;ubiquitin protein ligase binding#GO:0031625 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;regulation of biological process#GO:0050789;protein metabolic process#GO:0019538;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;proteasomal protein catabolic process#GO:0010498;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of protein metabolic process#GO:0051246;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;regulation of proteolysis#GO:0030162 nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8037684|UniProtKB=A0ACM8DSV8 A0ACM8DSV8 thoc7 PTHR23405:SF5 MAINTENANCE OF KILLER 16 MAK16 PROTEIN-RELATED THO COMPLEX SUBUNIT 7 cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;nucleocytoplasmic transport#GO:0006913;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;transport#GO:0006810;gene expression#GO:0010467;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;transcription export complex#GO:0000346;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC121834812|UniProtKB=A0ACM8FR97 A0ACM8FR97 LOC121834812 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844583|UniProtKB=A0ACM8FP16 A0ACM8FP16 PTHR10574:SF449 NETRIN/LAMININ-RELATED LAMININ SUBUNIT ALPHA extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;anatomical structure development#GO:0048856;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;developmental process#GO:0032502;neuron differentiation#GO:0030182;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;neuron projection guidance#GO:0097485;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;cellular process#GO:0009987;neuron projection development#GO:0031175;axon guidance#GO:0007411;axon development#GO:0061564;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;tissue development#GO:0009888 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 IXOSC|EnsemblGenome=LOC8041990|UniProtKB=A0ACM8E0U2 A0ACM8E0U2 LOC8041990 PTHR10804:SF11 PROTEASE FAMILY M24 METHIONYL AMINOPEPTIDASE, AMINOPEPTIDASE P PROLIFERATION-ASSOCIATED PROTEIN 2G4 protease#PC00190 IXOSC|EnsemblGenome=LOC115320517|UniProtKB=A0ACM8E121 A0ACM8E121 LOC115320517 PTHR46680:SF3 NF-KAPPA-B INHIBITOR ALPHA NF-KAPPA-B INHIBITOR CACTUS RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;protein binding#GO:0005515;DNA-binding transcription factor binding#GO:0140297;transcription factor binding#GO:0008134;binding#GO:0005488;molecular sequestering activity#GO:0140313;protein sequestering activity#GO:0140311 regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;negative regulation of intracellular signal transduction#GO:1902532;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;negative regulation of canonical NF-kappaB signal transduction#GO:0043124;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;regulation of canonical NF-kappaB signal transduction#GO:0043122;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 Toll pathway-drosophila#P06217>CACT#P06342 IXOSC|EnsemblGenome=LOC115332596|UniProtKB=A0ACM8EIZ5 A0ACM8EIZ5 LOC120837780 PTHR15243:SF0 SERINE/THREONINE-PROTEIN KINASE 19 WINGED HELIX REPAIR FACTOR 1 double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;nucleic acid binding#GO:0003676;binding#GO:0005488 regulation of cellular response to stress#GO:0080135;regulation of response to stress#GO:0080134;regulation of response to stimulus#GO:0048583;regulation of DNA repair#GO:0006282;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA metabolic process#GO:0051052 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8039546|UniProtKB=A0ACM8EKY2 A0ACM8EKY2 LOC8039546 PTHR33539:SF1 UPF0764 PROTEIN C16ORF89 UPF0764 PROTEIN C16ORF89 membrane#GO:0016020;cytosol#GO:0005829;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121047843|UniProtKB=A0ACM8FH03 A0ACM8FH03 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037716|UniProtKB=A0ACM8EP31 A0ACM8EP31 LOC8037716 PTHR11346:SF191 GALECTIN GALECTIN carbohydrate binding#GO:0030246;carbohydrate derivative binding#GO:0097367;binding#GO:0005488 extracellular matrix protein#PC00102 IXOSC|EnsemblGenome=LOC115317898|UniProtKB=A0ACM8F3N8 A0ACM8F3N8 LOC115317898 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115321067|UniProtKB=A0ACM8E1M1 A0ACM8E1M1 LOC115321067 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115317305|UniProtKB=A0ACM8EK56 A0ACM8EK56 LOC115317305 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120844643|UniProtKB=A0ACM8EZA2 A0ACM8EZA2 LOC120844643 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120836288|UniProtKB=A0ACM8EGY6 A0ACM8EGY6 LOC120836288 PTHR10590:SF24 SODIUM/NUCLEOSIDE COTRANSPORTER CONCENTRATIVE NUCLEOSIDE TRANSPORTER 1-RELATED solute:sodium symporter activity#GO:0015370;nucleobase-containing compound transmembrane transporter activity#GO:0015932;carbohydrate derivative transmembrane transporter activity#GO:1901505;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;nucleoside transmembrane transporter activity#GO:0005337;monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;metal ion transmembrane transporter activity#GO:0046873;active transmembrane transporter activity#GO:0022804;sodium ion transmembrane transporter activity#GO:0015081;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291 nucleobase-containing compound transport#GO:0015931;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;nitrogen compound transport#GO:0071705;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;transport#GO:0006810 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC120835956|UniProtKB=A0ACM8G7U3 A0ACM8G7U3 LOC120835956 PTHR42899:SF1 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 SPERMATOGENESIS-ASSOCIATED PROTEIN 20 IXOSC|EnsemblGenome=LOC8036234|UniProtKB=A0ACM8DHA3 A0ACM8DHA3 mRpS6 PTHR21011:SF17 MITOCHONDRIAL 28S RIBOSOMAL PROTEIN S6 SMALL RIBOSOMAL SUBUNIT PROTEIN BS6M structural molecule activity#GO:0005198;RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735;rRNA binding#GO:0019843 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840;membraneless organelle#GO:0043228;mitochondrial small ribosomal subunit#GO:0005763;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC120840989|UniProtKB=A0ACM8EQS5 A0ACM8EQS5 LOC120840989 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC120850533|UniProtKB=A0ACM8G451 A0ACM8G451 LOC120850533 PTHR43272:SF118 LONG-CHAIN-FATTY-ACID--COA LIGASE LONG-CHAIN-FATTY-ACID--COA LIGASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 lipid metabolic process#GO:0006629;developmental process#GO:0032502;neuron differentiation#GO:0030182;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;neurogenesis#GO:0022008;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;long-chain fatty acid metabolic process#GO:0001676;organophosphate metabolic process#GO:0019637;nervous system development#GO:0007399;nucleobase-containing compound metabolic process#GO:0006139;multicellular organismal process#GO:0032501;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;oxoacid metabolic process#GO:0043436;system development#GO:0048731;anatomical structure development#GO:0048856;purine-containing compound metabolic process#GO:0072521;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;monocarboxylic acid metabolic process#GO:0032787;nucleoside phosphate metabolic process#GO:0006753;cell differentiation#GO:0030154;small molecule metabolic process#GO:0044281 membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lipid droplet#GO:0005811;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;membrane#GO:0016020;cell periphery#GO:0071944 ligase#PC00142 IXOSC|EnsemblGenome=LOC8053085|UniProtKB=A0ACM8F6F2 A0ACM8F6F2 LOC8053085 PTHR12411:SF1051 CYSTEINE PROTEASE FAMILY C1-RELATED CATHEPSIN F cysteine-type peptidase activity#GO:0008234;catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;cysteine-type endopeptidase activity#GO:0004197;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 protease#PC00190;protein modifying enzyme#PC00260;cysteine protease#PC00081 IXOSC|EnsemblGenome=LOC115310841|UniProtKB=A0ACM8DQD5 A0ACM8DQD5 PIG-G PTHR23072:SF0 PHOSPHATIDYLINOSITOL GLYCAN-RELATED GPI ETHANOLAMINE PHOSPHATE TRANSFERASE 2, CATALYTIC SUBUNIT transferase activity#GO:0016740;catalytic activity#GO:0003824;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;glycolipid biosynthetic process#GO:0009247;phospholipid metabolic process#GO:0006644;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;liposaccharide metabolic process#GO:1903509;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;carbohydrate derivative biosynthetic process#GO:1901137;macromolecule metabolic process#GO:0043170;lipid metabolic process#GO:0006629;GPI anchor metabolic process#GO:0006505;glycerophospholipid biosynthetic process#GO:0046474;metabolic process#GO:0008152;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;GPI anchor biosynthetic process#GO:0006506;glycerophospholipid metabolic process#GO:0006650;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;carbohydrate derivative metabolic process#GO:1901135;organophosphate metabolic process#GO:0019637 membrane#GO:0016020;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8053993|UniProtKB=A0ACM8E6K5 A0ACM8E6K5 LOC8053993 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877;ligase activity#GO:0016874 ligase#PC00142 IXOSC|EnsemblGenome=LOC121836298|UniProtKB=A0ACM8FY79 A0ACM8FY79 LOC121836298 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041357|UniProtKB=A0ACM8FJ44 A0ACM8FJ44 LOC8041357 PTHR47537:SF1 CUBILIN CUB DOMAIN-CONTAINING PROTEIN cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8026309|UniProtKB=A0ACM8E4N7 A0ACM8E4N7 LOC8026309 PTHR13141:SF4 TRANSMEMBRANE PROTEIN 242 TRANSMEMBRANE PROTEIN 242 IXOSC|EnsemblGenome=LOC8025180|UniProtKB=A0ACM8EE01 A0ACM8EE01 LOC8025180 PTHR46297:SF1 ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN ZINC FINGER CCCH-TYPE WITH G PATCH DOMAIN-CONTAINING PROTEIN sequence-specific double-stranded DNA binding#GO:1990837;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription repressor activity, RNA polymerase II-specific#GO:0001227;sequence-specific DNA binding#GO:0043565;DNA-binding transcription repressor activity#GO:0001217;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC120846180|UniProtKB=A0ACM8G0J7 A0ACM8G0J7 LOC120846180 PTHR24416:SF527 TYROSINE-PROTEIN KINASE RECEPTOR PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;molecular transducer activity#GO:0060089;transmembrane receptor protein tyrosine kinase activity#GO:0004714;transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713 cell surface receptor signaling pathway#GO:0007166;regulation of response to stimulus#GO:0048583;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;signal transduction#GO:0007165;cellular process#GO:0009987;regulation of TOR signaling#GO:0032006;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;signaling#GO:0023052;regulation of cell communication#GO:0010646;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716 membrane#GO:0016020;signaling receptor complex#GO:0043235;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8053529|UniProtKB=A0ACM8E3U9 A0ACM8E3U9 sotv PTHR11062:SF381 EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED EXOSTOSIN-2 transferase activity#GO:0016740;catalytic activity#GO:0003824;glucuronosyltransferase activity#GO:0015020;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;glycosyltransferase activity#GO:0016757;acetylglucosaminyltransferase activity#GO:0008375 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8029198|UniProtKB=A0ACM8EVX3 A0ACM8EVX3 LOC8029198 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ATP-dependent activity#GO:0140657;ligase activity#GO:0016874;ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule metabolic process#GO:0044281;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8040501|UniProtKB=A0ACM8G5U5 A0ACM8G5U5 Mbs PTHR24179:SF21 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 12B phosphatase regulator activity#GO:0019208;enzyme regulator activity#GO:0030234;molecular function inhibitor activity#GO:0140678;molecular function regulator activity#GO:0098772;protein phosphatase regulator activity#GO:0019888;enzyme inhibitor activity#GO:0004857 cellular process#GO:0009987;neuron projection development#GO:0031175;plasma membrane bounded cell projection organization#GO:0120036;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;anatomical structure development#GO:0048856 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 protein-binding activity modulator#PC00095;phosphatase modulator#PC00184 IXOSC|EnsemblGenome=LOC121838132|UniProtKB=A0ACM8G879 A0ACM8G879 LOC121838132 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310234|UniProtKB=A0ACM8DPJ8 A0ACM8DPJ8 LOC115310234 PTHR39940:SF4 PROTHORACICOTROPIC HORMONE, ISOFORM F PROTEIN TRUNK receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;signaling receptor activator activity#GO:0030546 cellular response to stimulus#GO:0051716;regulation of hormone levels#GO:0010817;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;regulation of lipid metabolic process#GO:0019216;cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;cell communication#GO:0007154;regulation of biological quality#GO:0065008;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;positive regulation of cellular process#GO:0048522;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of steroid biosynthetic process#GO:0050810;regulation of lipid biosynthetic process#GO:0046890;biological regulation#GO:0065007;cell surface receptor signaling pathway#GO:0007166;regulation of biosynthetic process#GO:0009889 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207;peptide hormone#PC00179 IXOSC|EnsemblGenome=LOC8037833|UniProtKB=A0ACM8DIA1 A0ACM8DIA1 LOC8037833 PTHR11616:SF332 SODIUM/CHLORIDE DEPENDENT TRANSPORTER TRANSPORTER monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;monoatomic anion transmembrane transporter activity#GO:0008509;secondary active transmembrane transporter activity#GO:0015291;amino acid transmembrane transporter activity#GO:0015171;amino acid:sodium symporter activity#GO:0005283;solute:sodium symporter activity#GO:0015370;carboxylic acid transmembrane transporter activity#GO:0046943;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;solute:monoatomic cation symporter activity#GO:0015294;transmembrane transporter activity#GO:0022857;chloride transmembrane transporter activity#GO:0015108 amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic ion transport#GO:0006811;sodium ion transmembrane transport#GO:0035725;sodium ion transport#GO:0006814;cellular process#GO:0009987;metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220 cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC120844568|UniProtKB=A0ACM8EYX8 A0ACM8EYX8 LOC120844568 PTHR47577:SF5 THAP DOMAIN-CONTAINING PROTEIN 6 THAP DOMAIN CONTAINING 6 IXOSC|EnsemblGenome=LOC115322412|UniProtKB=A0ACM8FZR9 A0ACM8FZR9 LOC115322412 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838652|UniProtKB=A0ACM8EL04 A0ACM8EL04 AP-1sigma PTHR11753:SF5 ADAPTOR COMPLEXES SMALL SUBUNIT FAMILY AP COMPLEX SUBUNIT SIGMA vesicle-mediated transport#GO:0016192;establishment of localization#GO:0051234;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 membrane traffic protein#PC00150;vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC120842308|UniProtKB=A0ACM8ETH4 A0ACM8ETH4 LOC120842308 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227 IXOSC|EnsemblGenome=LOC8039030|UniProtKB=A0ACM8EDF3 A0ACM8EDF3 LOC8039030 PTHR21615:SF2 CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1 CYCLIN N-TERMINAL DOMAIN-CONTAINING PROTEIN 1 Cell cycle#P00013>Proteasome#P00480 IXOSC|EnsemblGenome=LOC8025783|UniProtKB=A0ACM8DGE9 A0ACM8DGE9 LOC8025783 PTHR10218:SF231 GTP-BINDING PROTEIN ALPHA SUBUNIT GUANINE NUCLEOTIDE BINDING PROTEIN (G PROTEIN) ALPHA V1 hydrolase activity, acting on acid anhydrides#GO:0016817;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562;cellular anatomical structure#GO:0110165;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494 heterotrimeric G-protein#PC00117;G-protein#PC00020 IXOSC|EnsemblGenome=LOC115327669|UniProtKB=A0ACM8F8S5 A0ACM8F8S5 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120848059|UniProtKB=A0ACM8F633 A0ACM8F633 LOC120848059 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508;protein maturation#GO:0051604;gene expression#GO:0010467;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8028630|UniProtKB=A0ACM8E6Q0 A0ACM8E6Q0 ush PTHR12958:SF3 FRIEND OF GATA2-RELATED ZINC FINGER PROTEIN USH binding#GO:0005488;transcription regulator activity#GO:0140110;protein binding#GO:0005515;RNA polymerase II-specific DNA-binding transcription factor binding#GO:0061629;DNA-binding transcription factor binding#GO:0140297;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;transcription factor binding#GO:0008134 positive regulation of biosynthetic process#GO:0009891;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;system development#GO:0048731;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of RNA biosynthetic process#GO:1902680;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;negative regulation of DNA-templated transcription#GO:0045892;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;animal gross anatomical part developmental process#GO:0160108;cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;circulatory system development#GO:0072359;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;animal organ development#GO:0048513;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;heart development#GO:0007507;positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;positive regulation of biological process#GO:0048518;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 transcription cofactor#PC00217;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115308867|UniProtKB=A0ACM8DN65 A0ACM8DN65 LOC115308867 PTHR10680:SF39 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 IXOSC|EnsemblGenome=LOC115325587|UniProtKB=A0ACM8F0D9 A0ACM8F0D9 LOC115325587 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 protein-containing complex#GO:0032991;ribonucleoprotein complex#GO:1990904 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115309840|UniProtKB=A0ACM8DP54 A0ACM8DP54 LOC115309840 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8051768|UniProtKB=A0ACM8DXZ3 A0ACM8DXZ3 RtGEF PTHR46026:SF1 RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F RHO-TYPE GUANINE NUCLEOTIDE EXCHANGE FACTOR, ISOFORM F nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;guanyl-nucleotide exchange factor activity#GO:0005085 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 guanyl-nucleotide exchange factor#PC00113;G-protein modulator#PC00022;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC115319221|UniProtKB=A0ACM8FH10 A0ACM8FH10 LOC115319221 PTHR12231:SF275 CTX-RELATED TYPE I TRANSMEMBRANE PROTEIN IG-LIKE DOMAIN-CONTAINING PROTEIN cell adhesion molecule binding#GO:0050839;cell adhesion mediator activity#GO:0098631;binding#GO:0005488;protein binding#GO:0005515 cell-cell adhesion#GO:0098609;cell adhesion#GO:0007155;cellular process#GO:0009987 cell junction#GO:0030054;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;cellular anatomical structure#GO:0110165 immunoglobulin superfamily cell adhesion molecule#PC00125;cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120840473|UniProtKB=A0ACM8EP64 A0ACM8EP64 LOC120840473 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120836807|UniProtKB=A0ACM8EGG2 A0ACM8EGG2 LOC120836807 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115316553|UniProtKB=A0ACM8G1X6 A0ACM8G1X6 LOC115316553 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849015|UniProtKB=A0ACM8F6W4 A0ACM8F6W4 LOC120849015 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;exopeptidase activity#GO:0008238;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;modified amino acid metabolic process#GO:0006575;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;small molecule catabolic process#GO:0044282 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115316976|UniProtKB=A0ACM8F931 A0ACM8F931 LOC115316976 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8038923|UniProtKB=A0ACM8E2S2 A0ACM8E2S2 wls PTHR13449:SF2 INTEGRAL MEMBRANE PROTEIN GPR177 PROTEIN WNTLESS HOMOLOG Wnt-protein binding#GO:0017147;protein binding#GO:0005515;binding#GO:0005488 macromolecule localization#GO:0033036;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;cellular process#GO:0009987;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;intracellular transport#GO:0046907;intracellular protein transport#GO:0006886;transport#GO:0006810;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;establishment of protein localization to extracellular region#GO:0035592;regulation of biological process#GO:0050789;protein localization to extracellular region#GO:0071692;signaling#GO:0023052;export from cell#GO:0140352;signal release#GO:0023061;protein secretion#GO:0009306;cell communication#GO:0007154;localization#GO:0051179;cellular localization#GO:0051641;secretion#GO:0046903;secretion by cell#GO:0032940;protein transport#GO:0015031 membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120842165|UniProtKB=A0ACM8FE49 A0ACM8FE49 LOC120842165 PTHR32019:SF2 R3H DOMAIN-CONTAINING PROTEIN 4 R3H DOMAIN-CONTAINING PROTEIN 4 IXOSC|EnsemblGenome=LOC120840668|UniProtKB=A0ACM8FEI8 A0ACM8FEI8 LOC120840668 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC8033763|UniProtKB=A0ACM8DTH4 A0ACM8DTH4 LOC8033763 PTHR33289:SF2 ANCHORAGE SUBUNIT, PUTATIVE-RELATED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8051371|UniProtKB=A0ACM8G2X1 A0ACM8G2X1 LOC8051371 PTHR24255:SF31 COMPLEMENT COMPONENT 1, S SUBCOMPONENT-RELATED CUB DOMAIN-CONTAINING PROTEIN catalytic activity#GO:0003824;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;serine-type endopeptidase activity#GO:0004252;catalytic activity, acting on a protein#GO:0140096;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 serine protease#PC00203 IXOSC|EnsemblGenome=LOC115328556|UniProtKB=A0ACM8EQ75 A0ACM8EQ75 LOC115328556 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8033620|UniProtKB=A0ACM8DP08 A0ACM8DP08 LOC8033620 PTHR23050:SF552 CALCIUM BINDING PROTEIN AT16150P-RELATED molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;calcium ion binding#GO:0005509 organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 calcium-binding protein#PC00060;calmodulin-related#PC00061 Heterotrimeric G-protein signaling pathway-rod outer segment phototransduction#P00028>Calmodulin#P00755;T cell activation#P00053>Calmodulin#P01305;B cell activation#P00010>Calmodulin#P00375;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>Phosphorylase b kinase#P00716 IXOSC|EnsemblGenome=LOC115332245|UniProtKB=A0ACM8FJE9 A0ACM8FJE9 LOC115332245 PTHR45774:SF4 BTB/POZ DOMAIN-CONTAINING LUTE, ISOFORM D cellular process#GO:0009987;multicellular organismal process#GO:0032501;cell differentiation#GO:0030154;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;developmental process#GO:0032502;cellular developmental process#GO:0048869;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;neurogenesis#GO:0022008;system development#GO:0048731 cytosol#GO:0005829;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115325347|UniProtKB=A0ACM8EIS4 A0ACM8EIS4 LOC115325347 PTHR24345:SF89 SERINE/THREONINE-PROTEIN KINASE PLK SERINE_THREONINE-PROTEIN KINASE PLK4 catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;kinase activity#GO:0016301;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 mitotic spindle organization#GO:0007052;mitotic cell cycle#GO:0000278;cytoskeleton organization#GO:0007010;cellular component organization#GO:0016043;microtubule cytoskeleton organization involved in mitosis#GO:1902850;cell cycle#GO:0007049;organelle organization#GO:0006996;cell cycle process#GO:0022402;cellular process#GO:0009987;microtubule cytoskeleton organization#GO:0000226;cellular component organization or biogenesis#GO:0071840;spindle organization#GO:0007051;microtubule-based process#GO:0007017;mitotic cell cycle process#GO:1903047 membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;condensed chromosome#GO:0000793;chromosome, centromeric region#GO:0000775;spindle#GO:0005819;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;condensed chromosome, centromeric region#GO:0000779;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;spindle pole#GO:0000922;kinetochore#GO:0000776 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8042692|UniProtKB=A0ACM8E3N8 A0ACM8E3N8 LOC8042692 PTHR10066:SF70 BETA-GLUCURONIDASE BETA-GLUCURONIDASE carbohydrate binding#GO:0030246;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;binding#GO:0005488;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC115309648|UniProtKB=A0ACM8DNV7 A0ACM8DNV7 LOC115309648 PTHR46599:SF7 PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN 4 SI:CH211-130M23.5 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115326096|UniProtKB=A0ACM8E6F2 A0ACM8E6F2 LOC115326096 PTHR13817:SF187 TITIN DOWN SYNDROME CELL ADHESION MOLECULE structural protein#PC00211 IXOSC|EnsemblGenome=LOC121837883|UniProtKB=A0ACM8G5J9 A0ACM8G5J9 LOC121837883 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115321146|UniProtKB=A0ACM8E112 A0ACM8E112 LOC115321146 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120847681|UniProtKB=A0ACM8F4N3 A0ACM8F4N3 PTHR45749:SF44 ZINC FINGER MYM-TYPE PROTEIN 1 ZINC FINGER MYM-TYPE PROTEIN 1 IXOSC|EnsemblGenome=LOC8023319|UniProtKB=A0ACM8E552 A0ACM8E552 PTHR24133:SF60 ANKYRIN DOMAIN-CONTAINING ANKYRIN REPEAT AND SOCS BOX-CONTAINING 3 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8052867|UniProtKB=A0ACM8FFJ6 A0ACM8FFJ6 LOC8052867 PTHR11266:SF128 PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17 MITOCHONDRIAL INNER MEMBRANE PROTEIN MPV17 channel activity#GO:0015267;passive transmembrane transporter activity#GO:0022803;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739 transporter#PC00227 IXOSC|EnsemblGenome=LOC121835835|UniProtKB=A0ACM8FW04 A0ACM8FW04 LOC121835835 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327841|UniProtKB=A0ACM8EGG6 A0ACM8EGG6 LOC115327841 PTHR10291:SF51 DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE FAMILY MEMBER DEHYDRODOLICHYL DIPHOSPHATE SYNTHASE COMPLEX SUBUNIT DHDDS transferase activity#GO:0016740;catalytic activity#GO:0003824;prenyltransferase activity#GO:0004659;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765 cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;isoprenoid biosynthetic process#GO:0008299;alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;isoprenoid metabolic process#GO:0006720 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;endomembrane system#GO:0012505 acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8025504|UniProtKB=A0ACM8DW96 A0ACM8DW96 LOC8025504 PTHR24247:SF238 5-HYDROXYTRYPTAMINE RECEPTOR DOPAMINE RECEPTOR 1 neurotransmitter receptor activity#GO:0030594;G protein-coupled amine receptor activity#GO:0008227;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 cellular process#GO:0009987;signal transduction#GO:0007165;synaptic signaling#GO:0099536;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;chemical synaptic transmission#GO:0007268;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;anterograde trans-synaptic signaling#GO:0098916;trans-synaptic signaling#GO:0099537;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 dendrite#GO:0030425;dendritic tree#GO:0097447;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025;membrane#GO:0016020;neuron projection#GO:0043005;cell periphery#GO:0071944 G-protein coupled receptor#PC00021;transmembrane signal receptor#PC00197 Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway#P00027>GoPCR#P00725;Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway#P00026>GiPCR#P00711;Dopamine receptor mediated signaling pathway#P05912>D1/D5#P05948 IXOSC|EnsemblGenome=LOC8026326|UniProtKB=A0ACM8DMP3 A0ACM8DMP3 LOC8026326 PTHR10856:SF20 CORONIN CORONIN-7 binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 actin filament-based process#GO:0030029;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531;supramolecular fiber organization#GO:0097435;positive regulation of signaling#GO:0023056;regulation of biological process#GO:0050789;positive regulation of signal transduction#GO:0009967;cellular component organization#GO:0016043;regulation of cell communication#GO:0010646;regulation of hippo signaling#GO:0035330;cell motility#GO:0048870;regulation of cellular process#GO:0050794;actin cytoskeleton organization#GO:0030036;positive regulation of cell communication#GO:0010647;positive regulation of intracellular signal transduction#GO:1902533;regulation of response to stimulus#GO:0048583;actin filament organization#GO:0007015;cellular component organization or biogenesis#GO:0071840;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;organelle organization#GO:0006996;biological regulation#GO:0065007;cytoskeleton organization#GO:0007010;regulation of signal transduction#GO:0009966;positive regulation of response to stimulus#GO:0048584;cell migration#GO:0016477 membrane#GO:0016020;cell periphery#GO:0071944;supramolecular complex#GO:0099080;supramolecular polymer#GO:0099081;plasma membrane#GO:0005886;intracellular membraneless organelle#GO:0043232;cytoskeleton#GO:0005856;actin filament#GO:0005884;membraneless organelle#GO:0043228;polymeric cytoskeletal fiber#GO:0099513;actin cytoskeleton#GO:0015629;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;supramolecular fiber#GO:0099512;intracellular anatomical structure#GO:0005622 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC115310073|UniProtKB=A0ACM8DP96 A0ACM8DP96 LOC115310073 PTHR10048:SF14 PHOSPHATIDYLINOSITOL KINASE LD28067P lipid kinase activity#GO:0001727;phosphotransferase activity, alcohol group as acceptor#GO:0016773;kinase activity#GO:0016301;phosphatidylinositol kinase activity#GO:0052742;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of cellular process#GO:0050794;phospholipid biosynthetic process#GO:0008654;cell motility#GO:0048870;response to stimulus#GO:0050896;glycerolipid metabolic process#GO:0046486;signaling#GO:0023052;phospholipid metabolic process#GO:0006644;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;organophosphate biosynthetic process#GO:0090407;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;phosphatidylinositol phosphate biosynthetic process#GO:0046854;lipid biosynthetic process#GO:0008610;cell migration#GO:0016477;glycerophospholipid metabolic process#GO:0006650;intracellular signaling cassette#GO:0141124;biosynthetic process#GO:0009058;biological regulation#GO:0065007;organophosphate metabolic process#GO:0019637;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;signal transduction#GO:0007165;phosphatidylinositol 3-kinase/protein kinase B signal transduction#GO:0043491;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;glycerophospholipid biosynthetic process#GO:0046474 plasma membrane#GO:0005886;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 kinase#PC00137 VEGF signaling pathway#P00056>PI3K#P01413;Axon guidance mediated by netrin#P00009>PI3K#P00363;Integrin signalling pathway#P00034>PI3K#P00936;p53 pathway feedback loops 2#P04398>PI3K#P04661;FGF signaling pathway#P00021>PI3K#P00640;Inflammation mediated by chemokine and cytokine signaling pathway#P00031>PI3K#P00868;Ras Pathway#P04393>PI3K#P04567;Apoptosis signaling pathway#P00006>PI3K#P00310;PDGF signaling pathway#P00047>PI3K#P01168;EGF receptor signaling pathway#P00018>PI3K#P00557;Insulin/IGF pathway-protein kinase B signaling cascade#P00033>PI3K#P00900;Hypoxia response via HIF activation#P00030>PI3K#P00823;p53 pathway#P00059>PI3K#P04609;Endothelin signaling pathway#P00019>PI3K#P00577;Angiogenesis#P00005>PI3K#P00236 IXOSC|EnsemblGenome=LOC115333167|UniProtKB=A0ACM8EYZ1 A0ACM8EYZ1 LOC115333167 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8023710|UniProtKB=A0ACM8ECW9 A0ACM8ECW9 LOC8023710 PTHR11188:SF144 ARRESTIN DOMAIN CONTAINING PROTEIN ARRESTIN C-TERMINAL-LIKE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC115326281|UniProtKB=A0ACM8F2P7 A0ACM8F2P7 LOC115326281 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120847150|UniProtKB=A0ACM8FP37 A0ACM8FP37 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115315150|UniProtKB=A0ACM8FIS9 A0ACM8FIS9 LOC115315150 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327754|UniProtKB=A0ACM8E7C9 A0ACM8E7C9 LOC115327754 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027239|UniProtKB=A0ACM8E3C9 A0ACM8E3C9 LOC8027239 PTHR12247:SF104 POLYCOMB GROUP PROTEIN POLYCOMB PROTEIN SFMBT protein binding#GO:0005515;binding#GO:0005488;chromatin binding#GO:0003682;histone binding#GO:0042393 negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of metabolic process#GO:0009892;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;negative regulation of macromolecule metabolic process#GO:0010605 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC121834877|UniProtKB=A0ACM8FS47 A0ACM8FS47 LOC121834877 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120843228|UniProtKB=A0ACM8FG55 A0ACM8FG55 LOC120843228 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;DNA-binding transcription activator activity#GO:0001216;transcription regulator activity#GO:0140110;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115330256|UniProtKB=A0ACM8FHI8 A0ACM8FHI8 LOC115330256 PTHR10322:SF23 DNA POLYMERASE CATALYTIC SUBUNIT DNA POLYMERASE DELTA CATALYTIC SUBUNIT exonuclease activity#GO:0004527;3'-5'-DNA exonuclease activity#GO:0008296;nuclease activity#GO:0004518;DNA exonuclease activity, producing 5'-phosphomonoesters#GO:0016895;transferase activity#GO:0016740;DNA exonuclease activity#GO:0004529;DNA polymerase activity#GO:0034061;catalytic activity, acting on DNA#GO:0140097;3'-5' exonuclease activity#GO:0008408;hydrolase activity#GO:0016787;DNA-directed DNA polymerase activity#GO:0003887;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nucleotidyltransferase activity#GO:0016779;hydrolase activity, acting on ester bonds#GO:0016788;transferase activity, transferring phosphorus-containing groups#GO:0016772;DNA nuclease activity#GO:0004536 response to stimulus#GO:0050896;base-excision repair#GO:0006284;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA replication#GO:0006260;cellular response to stimulus#GO:0051716;DNA-templated DNA replication#GO:0006261;cellular response to stress#GO:0033554;nucleotide-excision repair#GO:0006289;nucleobase-containing compound metabolic process#GO:0006139;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;protein-DNA complex#GO:0032993;replication fork#GO:0005657;replisome#GO:0030894;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;nuclear replication fork#GO:0043596;intracellular organelle lumen#GO:0070013;nuclear chromosome#GO:0000228;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;transferase complex#GO:1990234;DNA polymerase complex#GO:0042575 DNA metabolism protein#PC00009 DNA replication#P00017>Pol delta#P00533 IXOSC|EnsemblGenome=LOC120839882|UniProtKB=A0ACM8ENA4 A0ACM8ENA4 LOC120839882 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;metabolic process#GO:0008152;sulfur compound metabolic process#GO:0006790 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8050873|UniProtKB=A0ACM8G874 A0ACM8G874 LOC8050873 PTHR23167:SF96 CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED ALPHA ACTININ 3-RELATED cellular component organization#GO:0016043;organelle organization#GO:0006996;actin filament-based process#GO:0030029;cellular process#GO:0009987;actin cytoskeleton organization#GO:0030036;cellular component organization or biogenesis#GO:0071840;cytoskeleton organization#GO:0007010 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8039649|UniProtKB=A0ACM8DUX7 A0ACM8DUX7 LOC8039649 PTHR45685:SF1 HELICASE SRCAP-RELATED CHROMATIN REMODELING PROTEIN DOMINO pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;histone binding#GO:0042393;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887 cellular component organization or biogenesis#GO:0071840;chromatin organization#GO:0006325;chromatin remodeling#GO:0006338;cellular component organization#GO:0016043;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;INO80-type complex#GO:0097346;intracellular organelle lumen#GO:0070013;ATPase complex#GO:1904949;Swr1 complex#GO:0000812;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;chromosome#GO:0005694;organelle lumen#GO:0043233;SWI/SNF superfamily-type complex#GO:0070603;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;nuclear chromosome#GO:0000228;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;chromatin#GO:0000785;nucleus#GO:0005634 Wnt signaling pathway#P00057>SWI/SNF#P01435 IXOSC|EnsemblGenome=LOC8026138|UniProtKB=A0ACM8E6P5 A0ACM8E6P5 LOC8026138 PTHR20855:SF3 ADIPOR/PROGESTIN RECEPTOR-RELATED LD03007P transmembrane signal receptor#PC00197;G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120844648|UniProtKB=A0ACM8EZ36 A0ACM8EZ36 LOC120844648 PTHR24302:SF15 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 3A8-LIKE monooxygenase activity#GO:0004497;catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120849613|UniProtKB=A0ACM8F871 A0ACM8F871 LOC120849613 PTHR46927:SF4 AGAP005574-PA THAP DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8036220|UniProtKB=A0ACM8E3M1 A0ACM8E3M1 LOC8036220 PTHR46927:SF3 AGAP005574-PA THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039628|UniProtKB=A0ACM8G7A6 A0ACM8G7A6 LOC8039628 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121838062|UniProtKB=A0ACM8G636 A0ACM8G636 LOC121838062 PTHR10380:SF173 CUTICLE PROTEIN PUPAL CUTICLE PROTEIN EDG-78E-LIKE PROTEIN extracellular matrix structural protein#PC00103 IXOSC|EnsemblGenome=LOC8028590|UniProtKB=A0ACM8DGQ7 A0ACM8DGQ7 LOC8028590 PTHR24335:SF4 MOTOR NEURON AND PANCREAS HOMEOBOX PROTEIN EXTRA-EXTRA transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 system development#GO:0048731;anatomical structure development#GO:0048856;multicellular organism development#GO:0007275;developmental process#GO:0032502;animal gross anatomical part developmental process#GO:0160108;nervous system development#GO:0007399;multicellular organismal process#GO:0032501;central nervous system development#GO:0007417 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115325747|UniProtKB=A0ACM8G0C6 A0ACM8G0C6 HDAC11 PTHR10625:SF23 HISTONE DEACETYLASE HDAC1-RELATED HISTONE DEACETYLASE 11 histone modifying activity#GO:0140993;catalytic activity, acting on a protein#GO:0140096;deacetylase activity#GO:0019213;catalytic activity#GO:0003824;deacylase activity#GO:0160215;histone deacetylase activity#GO:0004407 epigenetic regulation of gene expression#GO:0040029;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;cellular process#GO:0009987;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;chromatin organization#GO:0006325;biological regulation#GO:0065007;chromatin remodeling#GO:0006338;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468 nuclear protein-containing complex#GO:0140513;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC121837788|UniProtKB=A0ACM8G4S8 A0ACM8G4S8 LOC121837788 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115314889|UniProtKB=A0ACM8F6F3 A0ACM8F6F3 LOC115314889 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115327066|UniProtKB=A0ACM8EIK6 A0ACM8EIK6 LOC115327066 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC115310934|UniProtKB=A0ACM8DQD7 A0ACM8DQD7 LOC115310934 PTHR11969:SF86 MAX DIMERIZATION, MAD MAD-LIKE PROTEIN 1 sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677 regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 basic helix-loop-helix transcription factor#PC00055;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8053203|UniProtKB=A0ACM8DYS1 A0ACM8DYS1 LOC8053203 PTHR14815:SF2 DDB1- AND CUL4-ASSOCIATED FACTOR 17 DDB1- AND CUL4-ASSOCIATED FACTOR 17 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;transferase complex#GO:1990234;catalytic complex#GO:1902494;Cul4-RING E3 ubiquitin ligase complex#GO:0080008 IXOSC|EnsemblGenome=LOC120848061|UniProtKB=A0ACM8F5C6 A0ACM8F5C6 LOC120848061 PTHR23192:SF92 OLFACTOMEDIN-RELATED FI21454P1 cell communication#GO:0007154;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 structural protein#PC00211 IXOSC|EnsemblGenome=LOC8032371|UniProtKB=A0ACM8DJF8 A0ACM8DJF8 LOC8032371 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782;transferase activity#GO:0016740;catalytic activity#GO:0003824 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8053982|UniProtKB=A0ACM8EIZ8 A0ACM8EIZ8 LOC8053982 PTHR11610:SF204 LIPASE PHOSPHOLIPASE A1 1-LIKE PROTEIN catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8036743|UniProtKB=A0ACM8EEX2 A0ACM8EEX2 LOC8036743 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;primary metabolic process#GO:0044238 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120840815|UniProtKB=A0ACM8G7E7 A0ACM8G7E7 LOC120840815 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120837834|UniProtKB=A0ACM8EHY0 A0ACM8EHY0 LOC120837834 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040404|UniProtKB=A0ACM8EUK0 A0ACM8EUK0 LOC8040404 PTHR16466:SF6 TELOMERE REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 TELOMERIC REPEAT-BINDING FACTOR 2-INTERACTING PROTEIN 1 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 telomere maintenance via telomere lengthening#GO:0010833;nucleobase-containing compound metabolic process#GO:0006139;telomere capping#GO:0016233;organelle organization#GO:0006996;response to stress#GO:0006950;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;DNA damage response#GO:0006974;response to stimulus#GO:0050896;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;telomere organization#GO:0032200;cellular response to stress#GO:0033554 membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;chromosome, telomeric region#GO:0000781;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;chromosomal region#GO:0098687;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome, telomeric repeat region#GO:0140445;nuclear telomere cap complex#GO:0000783;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-DNA complex#GO:0032993;organelle#GO:0043226 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC8044025|UniProtKB=A0ACM8DL44 A0ACM8DL44 LOC8044025 PTHR23032:SF13 BRO1 DOMAIN-CONTAINING PROTEIN BROX BRO1 DOMAIN-CONTAINING PROTEIN BROX IXOSC|EnsemblGenome=LOC8034270|UniProtKB=A0ACM8DV24 A0ACM8DV24 LOC8034270 PTHR31095:SF3 RIKEN CDNA 9930021J03 GENE BROMODOMAIN CONTAINING 10 IXOSC|EnsemblGenome=LOC120849906|UniProtKB=A0ACM8FW93 A0ACM8FW93 LOC120849906 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC121834468|UniProtKB=A0ACM8FNS6 A0ACM8FNS6 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120846349|UniProtKB=A0ACM8F238 A0ACM8F238 LOC120846349 PTHR46065:SF8 E3 UBIQUITIN-PROTEIN LIGASE MARCH 2/3 FAMILY MEMBER FI20425P1 catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;ubiquitin-protein transferase activity#GO:0004842;aminoacyltransferase activity#GO:0016755 macromolecule metabolic process#GO:0043170;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;protein modification by small protein conjugation or removal#GO:0070647;metabolic process#GO:0008152;protein ubiquitination#GO:0016567;post-translational protein modification#GO:0043687;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;cellular process#GO:0009987 ubiquitin-protein ligase#PC00234;protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC115315821|UniProtKB=A0ACM8DVQ6 A0ACM8DVQ6 LOC115315821 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC115323392|UniProtKB=A0ACM8EH69 A0ACM8EH69 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120847351|UniProtKB=A0ACM8F3U2 A0ACM8F3U2 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8028513|UniProtKB=A0ACM8ES19 A0ACM8ES19 LOC8028513 PTHR48534:SF1 METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308775|UniProtKB=A0ACM8EMJ8 A0ACM8EMJ8 PTHR35617:SF4 PHAGE_INTEGRASE DOMAIN-CONTAINING PROTEIN TYR RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842566|UniProtKB=A0ACM8EU38 A0ACM8EU38 PTHR33395:SF22 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN cell adhesion#GO:0007155;developmental process#GO:0032502;post-embryonic development#GO:0009791;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;multicellular organism development#GO:0007275;anatomical structure development#GO:0048856;animal organ development#GO:0048513;heart morphogenesis#GO:0003007;anatomical structure morphogenesis#GO:0009653;cellular process#GO:0009987;heart development#GO:0007507;circulatory system development#GO:0072359;animal organ morphogenesis#GO:0009887;multicellular organismal process#GO:0032501 extracellular matrix#GO:0031012;external encapsulating structure#GO:0030312;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120850778|UniProtKB=A0ACM8FB35 A0ACM8FB35 LOC120850778 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027930|UniProtKB=A0ACM8DJH4 A0ACM8DJH4 LOC8027930 PTHR12981:SF0 ZINC FINGER PROTEIN-LIKE 1 ZINC FINGER PROTEIN-LIKE 1 intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115330668|UniProtKB=A0ACM8G4F9 A0ACM8G4F9 LOC115330668 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838289|UniProtKB=A0ACM8G514 A0ACM8G514 LOC120838289 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC115331485|UniProtKB=A0ACM8F8P0 A0ACM8F8P0 LOC115331485 PTHR11208:SF140 RNA-BINDING PROTEIN RELATED GH05812P-RELATED mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 regulation of RNA metabolic process#GO:0051252;regulation of alternative mRNA splicing, via spliceosome#GO:0000381;regulation of biological process#GO:0050789;regulation of mRNA splicing, via spliceosome#GO:0048024;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of gene expression#GO:0010468;regulation of mRNA metabolic process#GO:1903311;regulation of biosynthetic process#GO:0009889;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;regulation of RNA splicing#GO:0043484;regulation of mRNA processing#GO:0050684;regulation of nucleobase-containing compound metabolic process#GO:0019219 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA processing factor#PC00147;RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC115324252|UniProtKB=A0ACM8EUG4 A0ACM8EUG4 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033123|UniProtKB=A0ACM8E9J9 A0ACM8E9J9 LOC8033123 PTHR15495:SF7 NEGATIVE REGULATOR OF VESICLE FORMATION-RELATED GPI INOSITOL-DEACYLASE catalytic activity#GO:0003824;deacylase activity#GO:0160215 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 transporter#PC00227 IXOSC|EnsemblGenome=LOC120841759|UniProtKB=A0ACM8G5I9 A0ACM8G5I9 LOC120841759 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC120837524|UniProtKB=A0ACM8EIM4 A0ACM8EIM4 LOC120837524 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328980|UniProtKB=A0ACM8E9D2 A0ACM8E9D2 LOC115328980 PTHR12150:SF13 CLASS IV SAM-BINDING METHYLTRANSFERASE-RELATED 28S RRNA (URIDINE-N(3))-METHYLTRANSFERASE metabolite interconversion enzyme#PC00262;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC115312434|UniProtKB=A0ACM8EGF4 A0ACM8EGF4 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8041261|UniProtKB=A0ACM8DKL0 A0ACM8DKL0 LOC8041261 PTHR44144:SF1 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 DNAJ HOMOLOG SUBFAMILY C MEMBER 9 heat shock protein binding#GO:0031072;binding#GO:0005488;protein binding#GO:0005515 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121838330|UniProtKB=A0ACM8G7P3 A0ACM8G7P3 LOC121838330 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038370|UniProtKB=A0ACM8EAX9 A0ACM8EAX9 LOC8038370 PTHR11699:SF211 ALDEHYDE DEHYDROGENASE-RELATED ALDEHYDE DEHYDROGENASE FAMILY 16 MEMBER A1 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor#GO:0016620;aldehyde dehydrogenase (NAD+) activity#GO:0004029;oxidoreductase activity, acting on the aldehyde or oxo group of donors#GO:0016903;catalytic activity#GO:0003824 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262 5-Hydroxytryptamine degredation#P04372>Aldehyde Dehydrogenase#P04402 IXOSC|EnsemblGenome=LOC121835718|UniProtKB=A0ACM8FWM0 A0ACM8FWM0 LOC121835718 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120846975|UniProtKB=A0ACM8F3L4 A0ACM8F3L4 LOC120846975 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8026725|UniProtKB=A0ACM8E2K6 A0ACM8E2K6 por PTHR13906:SF12 PORCUPINE PROTEIN-SERINE O-PALMITOLEOYLTRANSFERASE PORCUPINE protein binding#GO:0005515;Wnt-protein binding#GO:0017147;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;acyltransferase activity#GO:0016746;catalytic activity#GO:0003824;binding#GO:0005488;transferase activity#GO:0016740 cell-cell signaling#GO:0007267;biological regulation#GO:0065007;cellular process#GO:0009987;establishment of protein localization#GO:0045184;macromolecule localization#GO:0033036;establishment of protein localization to extracellular region#GO:0035592;intracellular protein localization#GO:0008104;establishment of localization#GO:0051234;lipid modification#GO:0030258;transport#GO:0006810;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;export from cell#GO:0140352;signaling#GO:0023052;protein localization to extracellular region#GO:0071692;regulation of biological process#GO:0050789;primary metabolic process#GO:0044238;protein transport#GO:0015031;secretion by cell#GO:0032940;secretion#GO:0046903;localization#GO:0051179;protein secretion#GO:0009306;cell communication#GO:0007154;signal release#GO:0023061 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC115309809|UniProtKB=A0ACM8FZI3 A0ACM8FZI3 LOC115309809 PTHR24096:SF149 LONG-CHAIN-FATTY-ACID--COA LIGASE LUCIFERIN 4-MONOOXYGENASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 ligase#PC00142 IXOSC|EnsemblGenome=LOC121837740|UniProtKB=A0ACM8G5Y7 A0ACM8G5Y7 LOC121837740 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8034657|UniProtKB=A0ACM8FR39 A0ACM8FR39 LOC8034657 PTHR12515:SF5 STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED PROTEIN SMAUG binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729;RNA binding#GO:0003723 post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;regulation of catabolic process#GO:0009894;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;regulation of nucleobase-containing compound metabolic process#GO:0019219;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of cellular process#GO:0050794;nuclear-transcribed mRNA poly(A) tail shortening#GO:0000289;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;positive regulation of RNA metabolic process#GO:0051254;macromolecule catabolic process#GO:0009057;positive regulation of mRNA metabolic process#GO:1903313;mRNA destabilization#GO:0061157;metabolic process#GO:0008152;regulation of mRNA metabolic process#GO:1903311;RNA destabilization#GO:0050779;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;positive regulation of metabolic process#GO:0009893;regulation of biological quality#GO:0065008;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;regulation of biological process#GO:0050789;regulation of mRNA stability#GO:0043488;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892 intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular organelle#GO:0043229;P-body#GO:0000932;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 IXOSC|EnsemblGenome=LOC121836557|UniProtKB=A0ACM8FZ40 A0ACM8FZ40 LOC121836557 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842844|UniProtKB=A0ACM8EUQ6 A0ACM8EUQ6 PTHR19282:SF534 TETRASPANIN TETRASPANIN FAMILY-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120847957|UniProtKB=A0ACM8F470 A0ACM8F470 PTHR48574:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032267|UniProtKB=A0ACM8F2U2 A0ACM8F2U2 NO66 PTHR13096:SF8 MINA53 MYC INDUCED NUCLEAR ANTIGEN RIBOSOMAL OXYGENASE 1 oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;catalytic activity, acting on a protein#GO:0140096;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;protein demethylase activity#GO:0140457;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824;histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC8030680|UniProtKB=A0ACM8E7H2 A0ACM8E7H2 PTHR11590:SF40 PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE HEMOCYTE PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 transferase#PC00220 IXOSC|EnsemblGenome=LOC115313306|UniProtKB=A0ACM8EHL9 A0ACM8EHL9 LOC115313306 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;binding#GO:0005488;catalytic activity#GO:0003824;small molecule binding#GO:0036094;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 monocarboxylic acid biosynthetic process#GO:0072330;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120836327|UniProtKB=A0ACM8F2U6 A0ACM8F2U6 trc PTHR24356:SF450 SERINE/THREONINE-PROTEIN KINASE SERINE_THREONINE-PROTEIN KINASE TRICORNERED phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;protein serine/threonine kinase activity#GO:0004674;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052;establishment or maintenance of cell polarity#GO:0007163;cell communication#GO:0007154;intracellular signal transduction#GO:0035556 non-receptor serine/threonine protein kinase#PC00167 IXOSC|EnsemblGenome=LOC8041309|UniProtKB=A0ACM8DKM9 A0ACM8DKM9 LOC8041309 PTHR17357:SF0 GM2 GANGLIOSIDE ACTIVATOR PROTEIN GANGLIOSIDE GM2 ACTIVATOR lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 glycolipid metabolic process#GO:0006664;liposaccharide metabolic process#GO:1903509;catabolic process#GO:0009056;carbohydrate derivative catabolic process#GO:1901136;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;ceramide metabolic process#GO:0006672;localization#GO:0051179;lipid localization#GO:0010876;lipid transport#GO:0006869;macromolecule localization#GO:0033036;cellular process#GO:0009987;lipid catabolic process#GO:0016042;carbohydrate derivative metabolic process#GO:1901135;establishment of localization#GO:0051234;sphingolipid metabolic process#GO:0006665;metabolic process#GO:0008152;transport#GO:0006810;lipid metabolic process#GO:0006629 cytoplasmic side of plasma membrane#GO:0009898;membrane#GO:0016020;cytoplasmic side of membrane#GO:0098562;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;side of membrane#GO:0098552;plasma membrane#GO:0005886 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8033954|UniProtKB=A0ACM8DRT5 A0ACM8DRT5 Bap55 PTHR11937:SF596 ACTIN BRAHMA ASSOCIATED PROTEIN 55KD structural molecule activity#GO:0005198;chromatin binding#GO:0003682;binding#GO:0005488;structural constituent of cytoskeleton#GO:0005200 regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;cellular process#GO:0009987;multicellular organismal process#GO:0032501;regulation of nucleobase-containing compound metabolic process#GO:0019219;nervous system development#GO:0007399;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;developmental process#GO:0032502;regulation of biosynthetic process#GO:0009889;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;chromatin remodeling#GO:0006338;animal gross anatomical part developmental process#GO:0160108;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;regulation of RNA metabolic process#GO:0051252;system development#GO:0048731 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ATPase complex#GO:1904949;protein acetyltransferase complex#GO:0031248;SWI/SNF complex#GO:0016514;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;acetyltransferase complex#GO:1902493;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;H4 histone acetyltransferase complex#GO:1902562;protein-containing complex#GO:0032991;NuA4 histone acetyltransferase complex#GO:0035267;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;histone acetyltransferase complex#GO:0000123;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 actin and actin related protein#PC00039 IXOSC|EnsemblGenome=LOC121835504|UniProtKB=A0ACM8FTL0 A0ACM8FTL0 LOC121835504 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC115312171|UniProtKB=A0ACM8G6S1 A0ACM8G6S1 LOC115312171 PTHR47642:SF5 ATP-DEPENDENT DNA HELICASE ATP-DEPENDENT DNA HELICASE DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121838145|UniProtKB=A0ACM8G6Y6 A0ACM8G6Y6 LOC121838145 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8030862|UniProtKB=A0ACM8DHL5 A0ACM8DHL5 LOC8030862 PTHR31777:SF0 TRANSMEMBRANE PROTEIN 169 TRANSMEMBRANE PROTEIN 169 IXOSC|EnsemblGenome=LOC120841834|UniProtKB=A0ACM8ESM3 A0ACM8ESM3 LOC120841834 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023415|UniProtKB=A0ACM8DXG7 A0ACM8DXG7 LOC8023415 PTHR43385:SF1 RIBOFLAVIN TRANSPORTER RIBJ RIBOFLAVIN TRANSPORTER RIBJ transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transporter#PC00227 IXOSC|EnsemblGenome=LOC115317841|UniProtKB=A0ACM8EYP8 A0ACM8EYP8 PTHR23080:SF153 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024153|UniProtKB=A0ACM8DTA0 A0ACM8DTA0 LOC8024153 PTHR15377:SF3 TRANSCRIPTION ELONGATION REGULATOR 1 WW DOMAIN-CONTAINING PROTEIN transcription coregulator activity#GO:0003712;binding#GO:0005488;RNA polymerase binding#GO:0070063;enzyme binding#GO:0019899;transcription regulator activity#GO:0140110;protein binding#GO:0005515 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC8042650|UniProtKB=A0ACM8DNY5 A0ACM8DNY5 VhaSFD PTHR10698:SF0 V-TYPE PROTON ATPASE SUBUNIT H V-TYPE PROTON ATPASE SUBUNIT H homeostatic process#GO:0042592;biological regulation#GO:0065007;monoatomic ion homeostasis#GO:0050801;intracellular monoatomic ion homeostasis#GO:0006873;vacuolar acidification#GO:0007035;regulation of biological quality#GO:0065008;cellular homeostasis#GO:0019725;intracellular chemical homeostasis#GO:0055082;regulation of pH#GO:0006885;intracellular monoatomic cation homeostasis#GO:0030003;chemical homeostasis#GO:0048878;monoatomic cation homeostasis#GO:0055080;regulation of intracellular pH#GO:0051453 intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;vacuolar proton-transporting V-type ATPase, V1 domain#GO:0000221;cation-transporting ATPase complex#GO:0090533;membrane protein complex#GO:0098796;ATPase dependent transmembrane transport complex#GO:0098533;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transmembrane transporter complex#GO:1902495;ATPase complex#GO:1904949;vacuolar proton-transporting V-type ATPase complex#GO:0016471;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;cytoplasm#GO:0005737;vacuole#GO:0005773;protein-containing complex#GO:0032991;membrane#GO:0016020;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;proton-transporting V-type ATPase complex#GO:0033176;transporter complex#GO:1990351;vacuolar membrane#GO:0005774;proton-transporting two-sector ATPase complex#GO:0016469 primary active transporter#PC00068;ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC120848084|UniProtKB=A0ACM8F559 A0ACM8F559 LOC120848084 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8043212|UniProtKB=A0ACM8DL33 A0ACM8DL33 LOC8043212 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;small molecule metabolic process#GO:0044281;lipid biosynthetic process#GO:0008610;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;fatty acid metabolic process#GO:0006631;monocarboxylic acid biosynthetic process#GO:0072330 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115325481|UniProtKB=A0ACM8E5V3 A0ACM8E5V3 LOC115325481 PTHR28474:SF1 TRANSMEMBRANE PROTEIN 72 TRANSMEMBRANE PROTEIN 72 IXOSC|EnsemblGenome=LOC8039050|UniProtKB=A0ACM8DS47 A0ACM8DS47 l(2)k05819 PTHR13219:SF6 TRANSMEMBRANE PROTEIN 94 TRANSMEMBRANE PROTEIN 94 magnesium ion transmembrane transporter activity#GO:0015095;ATPase-coupled transmembrane transporter activity#GO:0042626;ATP-dependent activity#GO:0140657;ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;monoatomic cation transmembrane transporter activity#GO:0008324;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;P-type ion transporter activity#GO:0015662;primary active transmembrane transporter activity#GO:0015399;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873 monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;monoatomic ion transmembrane transport#GO:0034220;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular localization#GO:0051641;transport#GO:0006810;magnesium ion transport#GO:0015693;intracellular transport#GO:0046907 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789 IXOSC|EnsemblGenome=LOC8053313|UniProtKB=A0ACM8EWI7 A0ACM8EWI7 LOC8053313 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN transferase#PC00220;acetyltransferase#PC00038 IXOSC|EnsemblGenome=LOC120845857|UniProtKB=A0ACM8F100 A0ACM8F100 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8026221|UniProtKB=A0ACM8EE80 A0ACM8EE80 LOC8026221 PTHR13455:SF7 TRANSCRIPTIONAL REPRESSOR P66-RELATED SIMJANG, ISOFORM E DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of cellular process#GO:0048523;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558 nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;transcription regulator complex#GO:0005667;histone deacetylase complex#GO:0000118;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;chromatin#GO:0000785;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ATPase complex#GO:1904949;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;chromosome#GO:0005694;SWI/SNF superfamily-type complex#GO:0070603;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membrane-bounded organelle#GO:0043231 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8034110|UniProtKB=A0ACM8DIY4 A0ACM8DIY4 LOC8034110 PTHR11071:SF582 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 chaperone#PC00072 IXOSC|EnsemblGenome=LOC120850392|UniProtKB=A0ACM8FAQ6 A0ACM8FAQ6 cpa PTHR10653:SF0 F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA F-ACTIN-CAPPING PROTEIN SUBUNIT ALPHA binding#GO:0005488;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 cytoskeleton organization#GO:0007010;regulation of actin cytoskeleton organization#GO:0032956;cellular process#GO:0009987;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular component organization or biogenesis#GO:0071840;regulation of anatomical structure size#GO:0090066;negative regulation of actin filament polymerization#GO:0030837;regulation of cellular component biogenesis#GO:0044087;regulation of cellular component organization#GO:0051128;regulation of cellular component size#GO:0032535;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;negative regulation of biological process#GO:0048519;cellular component organization#GO:0016043;regulation of protein-containing complex assembly#GO:0043254;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of actin filament length#GO:0030832;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;negative regulation of protein depolymerization#GO:1901880;regulation of actin filament polymerization#GO:0030833;regulation of actin filament organization#GO:0110053;regulation of protein depolymerization#GO:1901879;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of actin filament depolymerization#GO:0030834;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of supramolecular fiber organization#GO:1902903;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of cytoskeleton organization#GO:0051494;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;actin filament-based process#GO:0030029 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell periphery#GO:0071944;cell cortex#GO:0005938;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoskeleton#GO:0005856;intracellular organelle#GO:0043229 non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC115325870|UniProtKB=A0ACM8EIM0 A0ACM8EIM0 LOC115325870 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120850418|UniProtKB=A0ACM8G1G5 A0ACM8G1G5 LOC120850418 PTHR22912:SF151 DISULFIDE OXIDOREDUCTASE DIHYDROLIPOYL DEHYDROGENASE, MITOCHONDRIAL binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;oxidoreductase activity, acting on a sulfur group of donors#GO:0016667;anion binding#GO:0043168;small molecule binding#GO:0036094;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363;nucleotide binding#GO:0000166 pyruvate metabolic process#GO:0006090;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;metabolic process#GO:0008152;monocarboxylic acid metabolic process#GO:0032787;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752 oxidoreductase complex#GO:1990204;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115311463|UniProtKB=A0ACM8FQN5 A0ACM8FQN5 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC115323556|UniProtKB=A0ACM8FBT8 A0ACM8FBT8 LOC115323556 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8032449|UniProtKB=A0ACM8EDC9 A0ACM8EDC9 LOC8032449 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC8040937|UniProtKB=A0ACM8FX58 A0ACM8FX58 LOC8040937 PTHR13720:SF55 WD-40 REPEAT PROTEIN ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE CG42247 protein binding#GO:0005515;binding#GO:0005488;microtubule binding#GO:0008017;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092 cellular component organization or biogenesis#GO:0071840;microtubule cytoskeleton organization#GO:0000226;cytoskeleton organization#GO:0007010;microtubule-based process#GO:0007017;organelle organization#GO:0006996;cellular component organization#GO:0016043;cellular process#GO:0009987 microtubule cytoskeleton#GO:0015630;intracellular membraneless organelle#GO:0043232;mitotic spindle#GO:0072686;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;spindle#GO:0005819;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 microtubule or microtubule-binding cytoskeletal protein#PC00157 IXOSC|EnsemblGenome=LOC8034829|UniProtKB=A0ACM8FL79 A0ACM8FL79 SMC3 PTHR43977:SF1 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 IXOSC|EnsemblGenome=LOC8023492|UniProtKB=A0ACM8DUH1 A0ACM8DUH1 LOC8023492 PTHR15818:SF2 G PATCH AND KOW-CONTAINING G-PATCH DOMAIN AND KOW MOTIFS-CONTAINING PROTEIN macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;RNA processing#GO:0006396;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 spliceosomal complex#GO:0005681;nucleus#GO:0005634;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC8026643|UniProtKB=A0ACM8EYX5 A0ACM8EYX5 LOC8026643 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175 macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8035862|UniProtKB=A0ACM8ER40 A0ACM8ER40 LOC8035862 PTHR33053:SF27 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040503|UniProtKB=A0ACM8G4T8 A0ACM8G4T8 LOC8040503 PTHR11783:SF100 SULFOTRANSFERASE SULT SULFOTRANSFERASE 4, ISOFORM A transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring sulphur-containing groups#GO:0016782;sulfotransferase activity#GO:0008146 cellular process#GO:0009987;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC121835555|UniProtKB=A0ACM8FU55 A0ACM8FU55 LOC121835555 PTHR48039:SF7 RNA-BINDING MOTIF PROTEIN 14B RNA-BINDING PROTEIN 28 nucleolus#GO:0005730;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8030232|UniProtKB=A0ACM8FUS1 A0ACM8FUS1 LOC8030232 PTHR44942:SF4 METHYLTRANSF_11 DOMAIN-CONTAINING PROTEIN METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115325300|UniProtKB=A0ACM8F1L3 A0ACM8F1L3 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115326745|UniProtKB=A0ACM8E6E2 A0ACM8E6E2 LOC115326745 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 telomere organization#GO:0032200;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;organelle organization#GO:0006996;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular component organization#GO:0016043 IXOSC|EnsemblGenome=LOC120845421|UniProtKB=A0ACM8F013 A0ACM8F013 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8034479|UniProtKB=A0ACM8DZY7 A0ACM8DZY7 LOC8034479 PTHR12224:SF0 BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;amino sugar metabolic process#GO:0006040 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115332614|UniProtKB=A0ACM8EDX3 A0ACM8EDX3 LOC115332614 PTHR24067:SF373 UBIQUITIN-CONJUGATING ENZYME E2 UBC CORE DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC121835202|UniProtKB=A0ACM8FTC2 A0ACM8FTC2 LOC121835202 PTHR10782:SF94 ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN SUPPRESSOR OF VARIEGATION 2-10, ISOFORM I ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-like protein transferase activity#GO:0019787;SUMO ligase activity#GO:0061665;SUMO transferase activity#GO:0019789;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;transferase activity#GO:0016740 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;protein sumoylation#GO:0016925;regulation of gene expression#GO:0010468;metabolic process#GO:0008152;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;protein modification process#GO:0036211;protein modification by small protein conjugation#GO:0032446;regulation of biological process#GO:0050789;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;protein modification by small protein conjugation or removal#GO:0070647 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleoplasm#GO:0005654;chromosome#GO:0005694;organelle lumen#GO:0043233;membraneless organelle#GO:0043228;intracellular membraneless organelle#GO:0043232;chromatin#GO:0000785;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974 ubiquitin-protein ligase#PC00234 Interferon-gamma signaling pathway#P00035>PIAS#P00958 IXOSC|EnsemblGenome=LOC8051179|UniProtKB=A0ACM8E8T8 A0ACM8E8T8 LOC8051179 PTHR22978:SF48 B-CELL TRANSLOCATION GENE ANTI-PROLIFERATIVE PROTEIN DOMAIN-CONTAINING PROTEIN regulation of biological process#GO:0050789;negative regulation of cell population proliferation#GO:0008285;negative regulation of cellular process#GO:0048523;negative regulation of biological process#GO:0048519;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of cell population proliferation#GO:0042127 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120836017|UniProtKB=A0ACM8EGB2 A0ACM8EGB2 LOC120836017 PTHR11690:SF248 AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED AMILORIDE-SENSITIVE SODIUM CHANNEL monoatomic cation transmembrane transporter activity#GO:0008324;channel activity#GO:0015267;ligand-gated monoatomic ion channel activity#GO:0015276;gated channel activity#GO:0022836;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic cation channel activity#GO:0005261;sodium channel activity#GO:0005272;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;ligand-gated monoatomic cation channel activity#GO:0099094;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803 metal ion transport#GO:0030001;monoatomic cation transmembrane transport#GO:0098655;monoatomic ion transmembrane transport#GO:0034220;sodium ion transmembrane transport#GO:0035725;cellular process#GO:0009987;sodium ion transport#GO:0006814;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC120837048|UniProtKB=A0ACM8EHF3 A0ACM8EHF3 LOC120837048 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;metabolic process#GO:0008152;proteolysis#GO:0006508 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC8036224|UniProtKB=A0ACM8E3Y7 A0ACM8E3Y7 LOC8036224 PTHR44461:SF1 QUINONE OXIDOREDUCTASE-LIKE PROTEIN 1 FERRY ENDOSOMAL RAB5 EFFECTOR COMPLEX SUBUNIT 4 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8024159|UniProtKB=A0ACM8DHZ6 A0ACM8DHZ6 LOC8024159 PTHR31457:SF2 METHYLMALONIC ACIDURIA AND HOMOCYSTINURIA TYPE C PROTEIN CYANOCOBALAMIN REDUCTASE _ ALKYLCOBALAMIN DEALKYLASE ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;flavin adenine dinucleotide binding#GO:0050660;anion binding#GO:0043168;small molecule binding#GO:0036094;heterocyclic compound binding#GO:1901363;oxidoreductase activity#GO:0016491;demethylase activity#GO:0032451;nucleotide binding#GO:0000166;oxidoreductase activity, acting on metal ions#GO:0016722;catalytic activity#GO:0003824 cellular process#GO:0009987;tetrapyrrole metabolic process#GO:0033013;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC120843137|UniProtKB=A0ACM8EV74 A0ACM8EV74 LOC120843137 PTHR34615:SF2 PX DOMAIN-CONTAINING PROTEIN EPHRIN RBD DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8041458|UniProtKB=A0ACM8EPL3 A0ACM8EPL3 Gclm PTHR13295:SF4 GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT GLUTAMATE--CYSTEINE LIGASE REGULATORY SUBUNIT enzyme binding#GO:0019899;binding#GO:0005488;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;protein binding#GO:0005515 biosynthetic process#GO:0009058;peptide metabolic process#GO:0006518;modified amino acid metabolic process#GO:0006575;glutathione metabolic process#GO:0006749;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;catalytic complex#GO:1902494 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC120848807|UniProtKB=A0ACM8F6I0 A0ACM8F6I0 LOC120848807 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE anion binding#GO:0043168;small molecule binding#GO:0036094;binding#GO:0005488;ion binding#GO:0043167;phosphatidylinositol bisphosphate binding#GO:1902936 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC8032556|UniProtKB=A0ACM8DJI6 A0ACM8DJI6 Cbl PTHR23007:SF11 CBL E3 UBIQUITIN-PROTEIN LIGASE CBL binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;ubiquitin protein ligase activity#GO:0061630;protein binding#GO:0005515;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;protein tyrosine kinase binding#GO:1990782;signaling receptor binding#GO:0005102;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity#GO:0003824;receptor tyrosine kinase binding#GO:0030971;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755 regulation of signaling#GO:0023051;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of ERBB signaling pathway#GO:1901184;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of response to stimulus#GO:0048583;negative regulation of cellular process#GO:0048523;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of epidermal growth factor receptor signaling pathway#GO:0042058;negative regulation of signal transduction#GO:0009968;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of response to stimulus#GO:0048585 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;membrane raft#GO:0045121;membrane microdomain#GO:0098857;cell periphery#GO:0071944 ligase#PC00142 EGF receptor signaling pathway#P00018>c-Cbl#P00544 IXOSC|EnsemblGenome=LOC8035088|UniProtKB=A0ACM8EKD4 A0ACM8EKD4 LOC8035088 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule metabolic process#GO:0044281;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8035594|UniProtKB=A0ACM8FC10 A0ACM8FC10 LOC8035594 PTHR13812:SF24 KETIMINE REDUCTASE MU-CRYSTALLIN KETIMINE REDUCTASE MU-CRYSTALLIN hormone binding#GO:0042562;binding#GO:0005488 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;reductase#PC00198 IXOSC|EnsemblGenome=LOC8037610|UniProtKB=A0ACM8EAU0 A0ACM8EAU0 PpV PTHR45619:SF10 SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED SERINE_THREONINE-PROTEIN PHOSPHATASE 6 CATALYTIC SUBUNIT catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578;catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;protein serine/threonine phosphatase activity#GO:0004722;phosphoprotein phosphatase activity#GO:0004721 mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082;mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cellular process#GO:0009987;cell cycle process#GO:0022402 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195;protein modifying enzyme#PC00260 FGF signaling pathway#P00021>PP2A#P00629;EGF receptor signaling pathway#P00018>PP2A#P00547 IXOSC|EnsemblGenome=LOC115331661|UniProtKB=A0ACM8EKA8 A0ACM8EKA8 LOC115331661 PTHR21041:SF17 DENDRITIC CELL-SPECIFIC TRANSMEMBRANE PROTEIN E3 UBIQUITIN-PROTEIN LIGASE DCST1 catalytic activity#GO:0003824;transferase activity#GO:0016740;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin protein ligase activity#GO:0061630;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;ubiquitin-like protein ligase activity#GO:0061659;ubiquitin-protein transferase activity#GO:0004842 fertilization#GO:0009566;reproductive process#GO:0022414;single fertilization#GO:0007338;cellular process#GO:0009987;cell-cell recognition#GO:0009988;sperm-egg recognition#GO:0035036;cell recognition#GO:0008037;sexual reproduction#GO:0019953 acrosomal vesicle#GO:0001669;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;secretory granule#GO:0030141;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;secretory vesicle#GO:0099503;vesicle#GO:0031982;organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231 IXOSC|EnsemblGenome=LOC8042694|UniProtKB=A0ACM8DVM1 A0ACM8DVM1 LOC8042694 PTHR22198:SF1 FERM DOMAIN-CONTAINING PROTEIN DUF7153 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043329|UniProtKB=A0ACM8DL37 A0ACM8DL37 LOC8043329 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8034678|UniProtKB=A0ACM8FIU6 A0ACM8FIU6 LOC8034678 PTHR11811:SF25 6-PHOSPHOGLUCONATE DEHYDROGENASE 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING binding#GO:0005488;small molecule binding#GO:0036094;nucleoside phosphate binding#GO:1901265;phosphogluconate dehydrogenase (decarboxylating) activity#GO:0004616;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;purine nucleotide binding#GO:0017076;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;nucleotide binding#GO:0000166;oxidoreductase activity#GO:0016491;heterocyclic compound binding#GO:1901363 nucleotide metabolic process#GO:0009117;pentose-phosphate shunt#GO:0006098;pyridine-containing compound metabolic process#GO:0072524;NADPH regeneration#GO:0006740;small molecule metabolic process#GO:0044281;glucose 6-phosphate metabolic process#GO:0051156;nucleoside phosphate metabolic process#GO:0006753;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine nucleotide metabolic process#GO:0006163;purine-containing compound metabolic process#GO:0072521;nucleobase-containing small molecule metabolic process#GO:0055086;metabolic process#GO:0008152;generation of precursor metabolites and energy#GO:0006091;pentose-phosphate shunt, oxidative branch#GO:0009051;nucleobase-containing compound metabolic process#GO:0006139;organophosphate metabolic process#GO:0019637;NADP+ metabolic process#GO:0006739;nicotinamide nucleotide metabolic process#GO:0046496;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 dehydrogenase#PC00092 Pentose phosphate pathway#P02762>Gluconate Dehydrogenase#P03070 IXOSC|EnsemblGenome=LOC8023225|UniProtKB=A0ACM8G8N3 A0ACM8G8N3 LOC8023225 PTHR12137:SF67 CARBOHYDRATE SULFOTRANSFERASE CARBOHYDRATE SULFOTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;sulfotransferase activity#GO:0008146;transferase activity, transferring sulphur-containing groups#GO:0016782 transferase#PC00220 IXOSC|EnsemblGenome=LOC8035593|UniProtKB=A0ACM8DJV4 A0ACM8DJV4 LOC8035593 PTHR16231:SF5 COMM DOMAIN-CONTAINING PROTEIN 4-8 FAMILY MEMBER COMM DOMAIN-CONTAINING PROTEIN 6 protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 cytokine-mediated signaling pathway#GO:0019221;response to peptide#GO:1901652;tumor necrosis factor-mediated signaling pathway#GO:0033209;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular response to cytokine stimulus#GO:0071345;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;signal transduction#GO:0007165;response to tumor necrosis factor#GO:0034612;biological regulation#GO:0065007;response to chemical#GO:0042221;response to cytokine#GO:0034097 protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC120842418|UniProtKB=A0ACM8EUU3 A0ACM8EUU3 LOC120842418 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8037675|UniProtKB=A0ACM8EZ63 A0ACM8EZ63 LOC8037675 PTHR16172:SF41 MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE MAJOR FACILITATOR SUPERFAMILY DOMAIN-CONTAINING PROTEIN 6-LIKE cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC121835382|UniProtKB=A0ACM8FT05 A0ACM8FT05 LOC121835382 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115331134|UniProtKB=A0ACM8EBX5 A0ACM8EBX5 LOC115331134 PTHR20371:SF1 ENOLASE-PHOSPHATASE E1 ENOLASE-PHOSPHATASE E1 hydrolase#PC00121;phosphatase#PC00181 IXOSC|EnsemblGenome=LOC121833341|UniProtKB=A0ACM8FLI0 A0ACM8FLI0 LOC121833341 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115318114|UniProtKB=A0ACM8DY92 A0ACM8DY92 LOC115318114 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037603|UniProtKB=A0ACM8EAC1 A0ACM8EAC1 LOC8037603 PTHR18843:SF7 TORSIN-1A-INTERACTING PROTEIN SI:DKEYP-82A1.6 membrane organization#GO:0061024;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;cellular component organization#GO:0016043 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8042129|UniProtKB=A0ACM8EDV1 A0ACM8EDV1 Tcs4 PTHR11735:SF6 TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE TRNA N6-ADENOSINE THREONYLCARBAMOYLTRANSFERASE, MITOCHONDRIAL mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147;RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC115332515|UniProtKB=A0ACM8FQV5 A0ACM8FQV5 LOC115332515 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of intracellular signal transduction#GO:1902531;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115316385|UniProtKB=A0ACM8DWC0 A0ACM8DWC0 LOC115316385 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115322299|UniProtKB=A0ACM8E2T2 A0ACM8E2T2 LOC115322299 PTHR46377:SF1 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 DUAL SPECIFICITY PROTEIN PHOSPHATASE 19 phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791;catalytic activity#GO:0003824;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity, acting on a protein#GO:0140096;phosphoric ester hydrolase activity#GO:0042578 regulation of JNK cascade#GO:0046328;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583;regulation of MAPK cascade#GO:0043408;regulation of intracellular signal transduction#GO:1902531;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 IXOSC|EnsemblGenome=LOC121834179|UniProtKB=A0ACM8FPD9 A0ACM8FPD9 PTHR33395:SF23 TRANSCRIPTASE, PUTATIVE-RELATED-RELATED REVERSE TRANSCRIPTASE IXOSC|EnsemblGenome=LOC8040148|UniProtKB=A0ACM8FIK4 A0ACM8FIK4 LOC8040148 PTHR43918:SF17 ACETYLCHOLINESTERASE ACETYLCHOLINESTERASE 1 catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689;hydrolase activity#GO:0016787 metabolic process#GO:0008152;cellular process#GO:0009987;catabolic process#GO:0009056 membrane#GO:0016020;cell periphery#GO:0071944;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 esterase#PC00097 Nicotinic acetylcholine receptor signaling pathway#P00044>AChE#P01093;Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>AChE#P01067;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>AChE#P01080 IXOSC|EnsemblGenome=LOC8041835|UniProtKB=A0ACM8E1B5 A0ACM8E1B5 LOC8041835 PTHR10073:SF54 DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL PMS1 PROTEIN HOMOLOG 1 DNA nuclease activity#GO:0004536;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;nuclease activity#GO:0004518;endonuclease activity#GO:0004519;catalytic activity, acting on DNA#GO:0140097;DNA endonuclease activity#GO:0004520 response to stress#GO:0006950;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular response to stimulus#GO:0051716;mismatch repair#GO:0006298;cellular process#GO:0009987;response to stimulus#GO:0050896;nucleobase-containing compound metabolic process#GO:0006139;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;DNA repair#GO:0006281;DNA damage response#GO:0006974;cellular response to stress#GO:0033554;macromolecule metabolic process#GO:0043170 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513 DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8053742|UniProtKB=A0ACM8DUQ2 A0ACM8DUQ2 PTHR15954:SF4 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 51 HOMOLOG cellular localization#GO:0051641;localization#GO:0051179;localization within membrane#GO:0051668;cytosolic transport#GO:0016482;endocytic recycling#GO:0032456;Golgi organization#GO:0007030;cellular component organization#GO:0016043;endosomal transport#GO:0016197;vesicle-mediated transport to the plasma membrane#GO:0098876;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;transport#GO:0006810;Golgi vesicle transport#GO:0048193;vacuolar transport#GO:0007034;intracellular transport#GO:0046907;endomembrane system organization#GO:0010256;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;organelle organization#GO:0006996;retrograde transport, endosome to Golgi#GO:0042147 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;intracellular vesicle#GO:0097708;vesicle tethering complex#GO:0099023;Golgi apparatus#GO:0005794;recycling endosome#GO:0055037;cytoplasm#GO:0005737;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8041429|UniProtKB=A0ACM8DKP1 A0ACM8DKP1 Mpcp2 PTHR45671:SF10 SOLUTE CARRIER FAMILY 25 (MITOCHONDRIAL CARRIER PHOSPHATE CARRIER), MEMBER 3, LIKE-RELATED-RELATED SOLUTE CARRIER FAMILY 25 MEMBER 3 transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;phosphate ion transport#GO:0006817;inorganic anion transport#GO:0015698;cellular process#GO:0009987;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial membrane#GO:0031966;mitochondrion#GO:0005739;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737 mitochondrial carrier protein#PC00158 IXOSC|EnsemblGenome=LOC8051162|UniProtKB=A0ACM8EIJ4 A0ACM8EIJ4 LOC8051162 PTHR45985:SF8 FAMILY NOT NAMED CHITIN DEACETYLASE-LIKE 5, ISOFORM B IXOSC|EnsemblGenome=LOC121836042|UniProtKB=A0ACM8FXS8 A0ACM8FXS8 LOC121836042 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047612|UniProtKB=A0ACM8FGB0 A0ACM8FGB0 LOC121047612 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;cellular process#GO:0009987;transport#GO:0006810 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121046262|UniProtKB=A0ACM8FDS0 A0ACM8FDS0 LOC121046262 PTHR37984:SF29 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037293|UniProtKB=A0ACM8FSH9 A0ACM8FSH9 LOC8037293 PTHR21257:SF61 DELTA(14)-STEROL REDUCTASE LAMIN-B RECEPTOR oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;catalytic activity#GO:0003824 biosynthetic process#GO:0009058;sterol biosynthetic process#GO:0016126;steroid metabolic process#GO:0008202;cholesterol biosynthetic process#GO:0006695;lipid biosynthetic process#GO:0008610;alcohol biosynthetic process#GO:0046165;cellular process#GO:0009987;secondary alcohol biosynthetic process#GO:1902653;sterol metabolic process#GO:0016125;steroid biosynthetic process#GO:0006694;small molecule biosynthetic process#GO:0044283;lipid metabolic process#GO:0006629;cholesterol metabolic process#GO:0008203;metabolic process#GO:0008152;alcohol metabolic process#GO:0006066;secondary alcohol metabolic process#GO:1902652;small molecule metabolic process#GO:0044281;primary metabolic process#GO:0044238 nuclear membrane#GO:0031965;nuclear inner membrane#GO:0005637;organelle membrane#GO:0031090;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;nuclear envelope#GO:0005635;cytoplasm#GO:0005737;membrane#GO:0016020;organelle inner membrane#GO:0019866;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle envelope#GO:0031967 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC120844919|UniProtKB=A0ACM8F129 A0ACM8F129 LOC120844919 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115315780|UniProtKB=A0ACM8DV65 A0ACM8DV65 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8032705|UniProtKB=A0ACM8DSN0 A0ACM8DSN0 Rpn7 PTHR14145:SF1 26S PROTESOME SUBUNIT 6 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 6 ubiquitin-dependent protein catabolic process#GO:0006511;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;catabolic process#GO:0009056;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238 peptidase complex#GO:1905368;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;proteasome complex#GO:0000502;membrane-bounded organelle#GO:0043227;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;proteasome regulatory particle, lid subcomplex#GO:0008541 Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC115312692|UniProtKB=A0ACM8G3F9 A0ACM8G3F9 LOC115312692 PTHR37162:SF12 HAT FAMILY DIMERISATION DOMAINCONTAINING PROTEIN-RELATED ZINC FINGER PROTEIN 862-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8043341|UniProtKB=A0ACM8FZW2 A0ACM8FZW2 LOC8043341 PTHR11537:SF294 VOLTAGE-GATED POTASSIUM CHANNEL POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAW transporter activity#GO:0005215;monoatomic ion transmembrane transporter activity#GO:0015075;monoatomic ion channel activity#GO:0005216;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267 potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;biological regulation#GO:0065007;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;cellular process#GO:0009987;regulation of membrane potential#GO:0042391;establishment of localization#GO:0051234;transport#GO:0006810;metal ion transport#GO:0030001;action potential#GO:0001508;transmembrane transport#GO:0055085;localization#GO:0051179;monoatomic cation transport#GO:0006812;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811 plasma membrane#GO:0005886;somatodendritic compartment#GO:0036477;presynaptic membrane#GO:0042734;plasma membrane region#GO:0098590;monoatomic ion channel complex#GO:0034702;cell periphery#GO:0071944;membrane#GO:0016020;axon terminus#GO:0043679;neuron projection membrane#GO:0032589;voltage-gated potassium channel complex#GO:0008076;neuronal cell body#GO:0043025;neuron projection terminus#GO:0044306;distal axon#GO:0150034;plasma membrane bounded cell projection#GO:0120025;plasma membrane protein complex#GO:0098797;membrane protein complex#GO:0098796;transmembrane transporter complex#GO:1902495;axon#GO:0030424;dendritic tree#GO:0097447;dendrite#GO:0030425;protein-containing complex#GO:0032991;presynapse#GO:0098793;neuron projection#GO:0043005;cell leading edge#GO:0031252;cell junction#GO:0030054;transporter complex#GO:1990351;cation channel complex#GO:0034703;synaptic membrane#GO:0097060;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;synapse#GO:0045202;cell body#GO:0044297;postsynapse#GO:0098794;cell projection membrane#GO:0031253;leading edge membrane#GO:0031256;postsynaptic membrane#GO:0045211 ion channel#PC00133;voltage-gated ion channel#PC00241 IXOSC|EnsemblGenome=LOC120849756|UniProtKB=A0ACM8G626 A0ACM8G626 LOC120849756 PTHR15827:SF2 CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN CYCLIN-DEPENDENT KINASE 2-INTERACTING PROTEIN nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;DNA replication#GO:0006260;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;metabolic process#GO:0008152;DNA metabolic process#GO:0006259 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 Cell cycle#P00013>Cdk2#P00485 IXOSC|EnsemblGenome=LOC115312436|UniProtKB=A0ACM8F5X5 A0ACM8F5X5 PTHR24111:SF6 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 LEUCINE-RICH REPEAT-CONTAINING PROTEIN 34 DNA metabolic process#GO:0006259;metabolic process#GO:0008152;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;chromosome organization#GO:0051276;telomere maintenance#GO:0000723;telomere organization#GO:0032200;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139 IXOSC|EnsemblGenome=LOC8032777|UniProtKB=A0ACM8FD31 A0ACM8FD31 LOC8032777 PTHR11933:SF10 TRNA 5-METHYLAMINOMETHYL-2-THIOURIDYLATE -METHYLTRANSFERASE MITOCHONDRIAL TRNA-SPECIFIC 2-THIOURIDYLASE 1 sulfurtransferase activity#GO:0016783;transferase activity, transferring sulphur-containing groups#GO:0016782;catalytic activity#GO:0003824;transferase activity#GO:0016740 cellular process#GO:0009987;mitochondrial RNA processing#GO:0000963;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA wobble position uridine thiolation#GO:0002143;tRNA wobble uridine modification#GO:0002098;tRNA wobble base modification#GO:0002097;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;mitochondrial RNA modification#GO:1900864;mitochondrial gene expression#GO:0140053;mitochondrial RNA metabolic process#GO:0000959;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;tRNA thio-modification#GO:0034227 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC115314925|UniProtKB=A0ACM8DUN3 A0ACM8DUN3 LOC115314925 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115316137|UniProtKB=A0ACM8G2L5 A0ACM8G2L5 LOC115316137 PTHR31511:SF13 PROTEIN CBG23764 SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115319232|UniProtKB=A0ACM8DZF3 A0ACM8DZF3 LOC115319232 PTHR45036:SF9 METHYLTRANSFERASE LIKE 7B METHYLTRANSFERASE 7B-LIKE PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;transferase activity, transferring one-carbon groups#GO:0016741;methyltransferase activity#GO:0008168 metabolite interconversion enzyme#PC00262;transferase#PC00220;methyltransferase#PC00155 IXOSC|EnsemblGenome=LOC8037516|UniProtKB=A0ACM8EYP5 A0ACM8EYP5 LOC8037516 PTHR42758:SF4 PHOSPHATIDYLGLYCEROL PHOSPHOLIPASE C GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE DOMAIN-CONTAINING PROTEIN 1 hydrolase activity#GO:0016787;lipase activity#GO:0016298;phosphatidylcholine lysophospholipase A1 activity#GO:0004622;carboxylic ester hydrolase activity#GO:0052689;phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;catalytic activity#GO:0003824;glycerophospholipase activity#GO:0004620;phospholipase activity#GO:0120569;hydrolase activity, acting on ester bonds#GO:0016788 organophosphate metabolic process#GO:0019637;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;lipid catabolic process#GO:0016042;cellular process#GO:0009987;phospholipid catabolic process#GO:0009395;catabolic process#GO:0009056;glycerophospholipid metabolic process#GO:0006650;glycerolipid metabolic process#GO:0046486;phospholipid metabolic process#GO:0006644;metabolic process#GO:0008152;glycerolipid catabolic process#GO:0046503;lipid metabolic process#GO:0006629;glycerophospholipid catabolic process#GO:0046475;organophosphate catabolic process#GO:0046434 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827;endoplasmic reticulum#GO:0005783 phospholipase#PC00186;lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120840922|UniProtKB=A0ACM8EQ54 A0ACM8EQ54 LOC120840922 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC115310443|UniProtKB=A0ACM8G1K9 A0ACM8G1K9 LOC115310443 PTHR33194:SF5 ZINC KNUCKLE DOMAINCONTAINING PROTEIN PROTEIN, PUTATIVE-RELATED IXOSC|EnsemblGenome=LOC115332769|UniProtKB=A0ACM8EE34 A0ACM8EE34 LOC115332769 PTHR13315:SF4 METALLO PHOSPHOESTERASE RELATED METALLOPHOSPHOESTERASE, ISOFORM E metabolic process#GO:0008152;glycerophospholipid biosynthetic process#GO:0046474;GPI anchor metabolic process#GO:0006505;lipid metabolic process#GO:0006629;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;organophosphate metabolic process#GO:0019637;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;glycerolipid biosynthetic process#GO:0045017;glycerophospholipid metabolic process#GO:0006650;GPI anchor biosynthetic process#GO:0006506;gene expression#GO:0010467;lipid biosynthetic process#GO:0008610;protein maturation#GO:0051604;biosynthetic process#GO:0009058;glycolipid biosynthetic process#GO:0009247;protein metabolic process#GO:0019538;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;glycerolipid metabolic process#GO:0046486;GPI anchored protein biosynthesis#GO:0180046;liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;phospholipid biosynthetic process#GO:0008654;phospholipid metabolic process#GO:0006644 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 metabolite interconversion enzyme#PC00262;esterase#PC00097;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115329633|UniProtKB=A0ACM8ESF2 A0ACM8ESF2 LOC115329633 PTHR37984:SF22 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115322806|UniProtKB=A0ACM8EH07 A0ACM8EH07 LOC115322806 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8033426|UniProtKB=A0ACM8DQI5 A0ACM8DQI5 LOC8033426 PTHR10210:SF53 RIBOSE-PHOSPHATE DIPHOSPHOKINASE FAMILY MEMBER GH23275P transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;transferase activity#GO:0016740;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234 carbohydrate derivative biosynthetic process#GO:1901137;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;ribose phosphate biosynthetic process#GO:0046390;organophosphate metabolic process#GO:0019637;ribose phosphate metabolic process#GO:0019693;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;organophosphate biosynthetic process#GO:0090407;nucleotide metabolic process#GO:0009117;nucleotide biosynthetic process#GO:0009165;purine-containing compound biosynthetic process#GO:0072522;purine nucleotide biosynthetic process#GO:0006164;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;primary metabolic process#GO:0044238;phosphorus metabolic process#GO:0006793;purine-containing compound metabolic process#GO:0072521;purine nucleotide metabolic process#GO:0006163 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494 metabolite interconversion enzyme#PC00262;nucleotide kinase#PC00172 IXOSC|EnsemblGenome=LOC8036506|UniProtKB=A0ACM8DUQ1 A0ACM8DUQ1 LOC8036506 PTHR46673:SF1 4F2 CELL-SURFACE ANTIGEN HEAVY CHAIN AMINO ACID TRANSPORTER HEAVY CHAIN SLC3A2 cellular process#GO:0009987;nitrogen compound transport#GO:0071705;L-amino acid transport#GO:0015807;branched-chain amino acid transport#GO:0015803;establishment of localization#GO:0051234;import into cell#GO:0098657;carboxylic acid transport#GO:0046942;transport#GO:0006810;amino acid transport#GO:0006865;organic acid transport#GO:0015849;alanine transport#GO:0032328;carboxylic acid transmembrane transport#GO:1905039;L-leucine transport#GO:0015820;import across plasma membrane#GO:0098739;L-alpha-amino acid transmembrane transport#GO:1902475;neutral amino acid transport#GO:0015804;amino acid transmembrane transport#GO:0003333;transmembrane transport#GO:0055085;localization#GO:0051179 apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886;membrane#GO:0016020;basal part of cell#GO:0045178;basolateral plasma membrane#GO:0016323;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;basal plasma membrane#GO:0009925 IXOSC|EnsemblGenome=LOC8044053|UniProtKB=A0ACM8DN39 A0ACM8DN39 NC2alpha PTHR10252:SF163 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED DR1-ASSOCIATED COREPRESSOR core promoter sequence-specific DNA binding#GO:0001046;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;DNA-templated transcription#GO:0006351;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;transcription by RNA polymerase II#GO:0006366;RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170 transcription repressor complex#GO:0017053;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8037982|UniProtKB=A0ACM8ET71 A0ACM8ET71 LOC8037982 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399 establishment of localization#GO:0051234;lipid transport#GO:0006869;localization#GO:0051179;lipid localization#GO:0010876;macromolecule localization#GO:0033036;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC120842369|UniProtKB=A0ACM8ETP4 A0ACM8ETP4 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8041195|UniProtKB=A0ACM8E4Z4 A0ACM8E4Z4 AsnRS-m PTHR22594:SF59 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINYL-TRNA SYNTHETASE catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;ligase activity#GO:0016874;catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640 protein biosynthetic process#GO:0160307;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;translation#GO:0006412;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;gene expression#GO:0010467;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;tRNA aminoacylation#GO:0043039;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399 cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC115330014|UniProtKB=A0ACM8F3J6 A0ACM8F3J6 LOC115330014 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8040838|UniProtKB=A0ACM8DH61 A0ACM8DH61 Ktl PTHR14499:SF148 POTASSIUM CHANNEL TETRAMERIZATION DOMAIN-CONTAINING GH08630P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115312861|UniProtKB=A0ACM8EUN0 A0ACM8EUN0 LOC115312861 PTHR43157:SF74 PHOSPHATIDYLINOSITOL-GLYCAN BIOSYNTHESIS CLASS F PROTEIN-RELATED DEHYDROGENASES, SHORT CHAIN-RELATED oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC121837366|UniProtKB=A0ACM8G4C6 A0ACM8G4C6 LOC121837366 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC8053765|UniProtKB=A0ACM8G817 A0ACM8G817 LOC8053765 PTHR12505:SF24 PHD FINGER TRANSCRIPTION FACTOR PROTEIN WINGED EYE DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8027403|UniProtKB=A0ACM8DJ23 A0ACM8DJ23 LOC8027403 PTHR43677:SF13 SHORT-CHAIN DEHYDROGENASE/REDUCTASE PROSTAGLANDIN REDUCTASE 3 oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115330707|UniProtKB=A0ACM8EBJ4 A0ACM8EBJ4 LOC115330707 PTHR23236:SF12 EUKARYOTIC TRANSLATION INITIATION FACTOR 4B/4H EUKARYOTIC INITIATION FACTOR 4B-RELATED poly(A) binding#GO:0008143;binding#GO:0005488;nucleic acid binding#GO:0003676;single-stranded RNA binding#GO:0003727;RNA binding#GO:0003723 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 translation initiation factor#PC00224;translation factor#PC00223;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120838348|UniProtKB=A0ACM8EKK5 A0ACM8EKK5 RasGAP1 PTHR10194:SF148 RAS GTPASE-ACTIVATING PROTEINS GTPASE-ACTIVATING PROTEIN GTPase-activating protein#PC00257 FGF signaling pathway#P00021>RasGAP#P00646;PDGF signaling pathway#P00047>RasGAP#P01152;EGF receptor signaling pathway#P00018>GAP#P00546 IXOSC|EnsemblGenome=LOC120845989|UniProtKB=A0ACM8F0H9 A0ACM8F0H9 LOC120845989 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8038981|UniProtKB=A0ACM8FIK3 A0ACM8FIK3 Tango9 PTHR13146:SF0 SOLUTE CARRIER FAMILY 35 MEMBER F6-RELATED SOLUTE CARRIER FAMILY 35 MEMBER F6 intracellular organelle#GO:0043229;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121833022|UniProtKB=A0ACM8FIW6 A0ACM8FIW6 LOC121833022 PTHR13243:SF1 HSPC111 PROTEIN-RELATED NUCLEOLAR PROTEIN 16 cellular component organization or biogenesis#GO:0071840;ribonucleoprotein complex biogenesis#GO:0022613;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribosome biogenesis#GO:0042254;cellular process#GO:0009987 organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC120836091|UniProtKB=A0ACM8F6H6 A0ACM8F6H6 LOC120836091 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8025047|UniProtKB=A0ACM8DIX6 A0ACM8DIX6 LOC8025047 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC8029674|UniProtKB=A0ACM8EBP8 A0ACM8EBP8 LOC8029674 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC121834992|UniProtKB=A0ACM8FS86 A0ACM8FS86 LOC121834992 PTHR12027:SF101 WNT RELATED PROTEIN WNT-4 binding#GO:0005488;signaling receptor binding#GO:0005102;cytokine activity#GO:0005125;molecular function activator activity#GO:0140677;protein binding#GO:0005515;G protein-coupled receptor binding#GO:0001664;frizzled binding#GO:0005109;receptor ligand activity#GO:0048018;signaling receptor regulator activity#GO:0030545;molecular function regulator activity#GO:0098772;signaling receptor activator activity#GO:0030546 generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;cell fate commitment#GO:0045165;anatomical structure development#GO:0048856;canonical Wnt signaling pathway#GO:0060070;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signaling#GO:0023052;regulation of cellular process#GO:0050794;Wnt signaling pathway#GO:0016055;response to stimulus#GO:0050896;cell differentiation#GO:0030154;cell surface receptor signaling pathway#GO:0007166;developmental process#GO:0032502;neuron differentiation#GO:0030182;neurogenesis#GO:0022008;cellular developmental process#GO:0048869;multicellular organism development#GO:0007275;cellular process#GO:0009987;signal transduction#GO:0007165;nervous system development#GO:0007399;biological regulation#GO:0065007;multicellular organismal process#GO:0032501 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 intercellular signal molecule#PC00207 Cadherin signaling pathway#P00012>Wnt#P00474;Alzheimer disease-presenilin pathway#P00004>Wnt#P00142;Wnt signaling pathway#P00057>Wnt#P01444 IXOSC|EnsemblGenome=LOC120844646|UniProtKB=A0ACM8EYU3 A0ACM8EYU3 LOC120844646 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC120839638|UniProtKB=A0ACM8ELM8 A0ACM8ELM8 LOC120839638 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040333|UniProtKB=A0ACM8DKK9 A0ACM8DKK9 LOC8040333 PTHR15362:SF4 PHOSPHATIDYLINOSITOL SYNTHASE CDP-DIACYLGLYCEROL--INOSITOL 3-PHOSPHATIDYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;phosphotransferase activity, for other substituted phosphate groups#GO:0016780;transferase activity, transferring phosphorus-containing groups#GO:0016772 glycerophospholipid biosynthetic process#GO:0046474;lipid metabolic process#GO:0006629;phosphatidylinositol metabolic process#GO:0046488;metabolic process#GO:0008152;glycerolipid biosynthetic process#GO:0045017;cellular process#GO:0009987;organophosphate metabolic process#GO:0019637;biosynthetic process#GO:0009058;glycerophospholipid metabolic process#GO:0006650;lipid biosynthetic process#GO:0008610;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;phospholipid metabolic process#GO:0006644;glycerolipid metabolic process#GO:0046486;phospholipid biosynthetic process#GO:0008654 organelle#GO:0043226;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 transferase#PC00220 IXOSC|EnsemblGenome=LOC8040082|UniProtKB=A0ACM8DKI3 A0ACM8DKI3 LOC8040082 PTHR24366:SF174 IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS IG-LIKE DOMAIN-CONTAINING PROTEIN immunoglobulin superfamily cell adhesion molecule#PC00125 IXOSC|EnsemblGenome=LOC121045978|UniProtKB=A0ACM8FBG6 A0ACM8FBG6 LOC121045978 PTHR45823:SF1 T-SNARE COILED-COIL HOMOLOGY DOMAIN-CONTAINING PROTEIN SAP DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120842296|UniProtKB=A0ACM8ETF3 A0ACM8ETF3 LOC120842296 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC8051065|UniProtKB=A0ACM8DNT5 A0ACM8DNT5 Pcl PTHR12628:SF21 POLYCOMB-LIKE TRANSCRIPTION FACTOR PHD-TYPE DOMAIN-CONTAINING PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;chromatin binding#GO:0003682;DNA binding#GO:0003677 regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;chromatin organization#GO:0006325;negative regulation of biosynthetic process#GO:0009890;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular process#GO:0009987 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC115318973|UniProtKB=A0ACM8DYH2 A0ACM8DYH2 LOC115318973 PTHR22639:SF14 GAG-RELATED PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115326902|UniProtKB=A0ACM8F9S1 A0ACM8F9S1 LOC115326902 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8026642|UniProtKB=A0ACM8E8D7 A0ACM8E8D7 LOC8026642 PTHR24095:SF244 ACETYL-COENZYME A SYNTHETASE ACETYL-COENZYME A SYNTHETASE ligase activity#GO:0016874;catalytic activity#GO:0003824;ligase activity, forming carbon-sulfur bonds#GO:0016877 acetyl-CoA metabolic process#GO:0006084;purine-containing compound biosynthetic process#GO:0072522;organophosphate biosynthetic process#GO:0090407;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;purine-containing compound metabolic process#GO:0072521;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;acyl-CoA metabolic process#GO:0006637;nucleobase-containing small molecule metabolic process#GO:0055086;organophosphate metabolic process#GO:0019637;sulfur compound metabolic process#GO:0006790;cellular process#GO:0009987;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058 ligase#PC00142 Acetate utilization#P02722>Acetyl-CoA synthetase#P02803 IXOSC|EnsemblGenome=LOC8053167|UniProtKB=A0ACM8EQJ4 A0ACM8EQJ4 Nasp PTHR15081:SF1 NUCLEAR AUTOANTIGENIC SPERM PROTEIN NASP -RELATED NUCLEAR AUTOANTIGENIC SPERM PROTEIN binding#GO:0005488;histone binding#GO:0042393;protein binding#GO:0005515 kinetochore assembly#GO:0051382;organelle assembly#GO:0070925;protein-containing complex organization#GO:0043933;chromosome organization#GO:0051276;cellular component organization or biogenesis#GO:0071840;kinetochore organization#GO:0051383;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003;membraneless organelle assembly#GO:0140694;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;chromatin organization#GO:0006325;cellular component assembly#GO:0022607 intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;intracellular membrane-bounded organelle#GO:0043231;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleoplasm#GO:0005654;organelle#GO:0043226 chaperone#PC00072 IXOSC|EnsemblGenome=LOC115324520|UniProtKB=A0ACM8F786 A0ACM8F786 LOC115324520 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;serine-type peptidase activity#GO:0008236;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171 primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC121835870|UniProtKB=A0ACM8FWZ0 A0ACM8FWZ0 LOC121835870 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024705|UniProtKB=A0ACM8G667 A0ACM8G667 LOC8024705 PTHR11473:SF43 AROMATIC AMINO ACID HYDROXYLASE TRYPTOPHAN 5-HYDROXYLASE 2 oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;monooxygenase activity#GO:0004497;catalytic activity#GO:0003824 metabolic process#GO:0008152;serotonin metabolic process#GO:0042428;phenol-containing compound biosynthetic process#GO:0046189;phenol-containing compound metabolic process#GO:0018958;indole-containing compound metabolic process#GO:0042430;cellular process#GO:0009987;serotonin biosynthetic process#GO:0042427;biosynthetic process#GO:0009058 plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cellular anatomical structure#GO:0110165;neuron projection#GO:0043005 metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 5-Hydroxytryptamine biosynthesis#P04371>Tryptophan hydroxylase#P04399 IXOSC|EnsemblGenome=LOC115310110|UniProtKB=A0ACM8DPB1 A0ACM8DPB1 LOC115310110 PTHR13803:SF4 SEC24-RELATED PROTEIN SECRETORY 24CD, ISOFORM C SNARE binding#GO:0000149;zinc ion binding#GO:0008270;protein binding#GO:0005515;metal ion binding#GO:0046872;cation binding#GO:0043169;ion binding#GO:0043167;binding#GO:0005488;small molecule binding#GO:0036094;transition metal ion binding#GO:0046914 organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;membrane organization#GO:0061024;intracellular transport#GO:0046907;Golgi vesicle transport#GO:0048193;transport#GO:0006810;establishment of localization#GO:0051234;cellular component organization or biogenesis#GO:0071840;vesicle budding from membrane#GO:0006900;vesicle organization#GO:0016050;cellular component organization#GO:0016043;COPII-coated vesicle budding#GO:0090114;cellular localization#GO:0051641;localization#GO:0051179;endoplasmic reticulum to Golgi vesicle-mediated transport#GO:0006888 ER to Golgi transport vesicle membrane#GO:0012507;endoplasmic reticulum exit site#GO:0070971;endoplasmic reticulum#GO:0005783;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;vesicle membrane#GO:0012506;membrane#GO:0016020;transport vesicle#GO:0030133;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;transport vesicle membrane#GO:0030658;cytoplasmic vesicle membrane#GO:0030659;vesicle coat#GO:0030120;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;coated membrane#GO:0048475;membrane coat#GO:0030117;COPII-coated ER to Golgi transport vesicle#GO:0030134;membrane-bounded organelle#GO:0043227;coated vesicle#GO:0030135;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;vesicle#GO:0031982;organelle#GO:0043226;cellular anatomical structure#GO:0110165;coated vesicle membrane#GO:0030662;intracellular membrane-bounded organelle#GO:0043231 vesicle coat protein#PC00235 IXOSC|EnsemblGenome=LOC8043969|UniProtKB=A0ACM8DM85 A0ACM8DM85 RpS16 PTHR21569:SF16 RIBOSOMAL PROTEIN S9 SMALL RIBOSOMAL SUBUNIT PROTEIN US9 nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735;structural molecule activity#GO:0005198;RNA binding#GO:0003723 rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072;RNA processing#GO:0006396;maturation of SSU-rRNA#GO:0030490;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085 small ribosomal subunit#GO:0015935;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;cytosolic small ribosomal subunit#GO:0022627;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8023969|UniProtKB=A0ACM8DPV0 A0ACM8DPV0 LOC8023969 PTHR12224:SF0 BETA-1,4-MANNOSYL-GLYCOPROTEIN BETA-1,4-N-ACETYLGLUCOSAMINYL-TRANSFERASE BETA-1,4-MANNOSYL-GLYCOPROTEIN 4-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE glycosyltransferase activity#GO:0016757;transferase activity#GO:0016740;catalytic activity#GO:0003824 amino sugar metabolic process#GO:0006040;metabolic process#GO:0008152;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 transferase#PC00220;glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC115313704|UniProtKB=A0ACM8DTH3 A0ACM8DTH3 LOC115313704 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8035692|UniProtKB=A0ACM8F0V4 A0ACM8F0V4 LOC8035692 PTHR11686:SF77 GAMMA GLUTAMYL TRANSPEPTIDASE RE13973P catalytic activity#GO:0003824;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 sulfur compound catabolic process#GO:0044273;catabolic process#GO:0009056;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protein modifying enzyme#PC00260;protease#PC00190 IXOSC|EnsemblGenome=LOC8023804|UniProtKB=A0ACM8DHK9 A0ACM8DHK9 RpL14 PTHR11127:SF2 60S RIBOSOMAL PROTEIN L14 LARGE RIBOSOMAL SUBUNIT PROTEIN EL14 RNA binding#GO:0003723;structural molecule activity#GO:0005198;nucleic acid binding#GO:0003676;binding#GO:0005488;structural constituent of ribosome#GO:0003735 cellular process#GO:0009987;ribosome biogenesis#GO:0042254;ribosomal large subunit biogenesis#GO:0042273;cellular component biogenesis#GO:0044085;ribonucleoprotein complex biogenesis#GO:0022613;cellular component organization or biogenesis#GO:0071840 intracellular organelle#GO:0043229;large ribosomal subunit#GO:0015934;ribonucleoprotein complex#GO:1990904;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;ribosome#GO:0005840;cytosolic large ribosomal subunit#GO:0022625;cytosolic ribosome#GO:0022626;cytosol#GO:0005829;cytoplasm#GO:0005737;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8040663|UniProtKB=A0ACM8FAP4 A0ACM8FAP4 Rab7 PTHR47981:SF45 RAB FAMILY RAS-RELATED PROTEIN RAB7 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772 vesicle-mediated transport#GO:0016192;organelle fusion#GO:0048284;cellular component assembly#GO:0022607;organelle membrane fusion#GO:0090174;membrane organization#GO:0061024;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;membrane fusion#GO:0061025;cellular process#GO:0009987;lysosome organization#GO:0007040;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;import into cell#GO:0098657;cellular component organization or biogenesis#GO:0071840;vesicle organization#GO:0016050;phagocytosis#GO:0006909;intracellular transport#GO:0046907;phagolysosome assembly#GO:0001845;lytic vacuole organization#GO:0080171;transport#GO:0006810;vacuolar transport#GO:0007034;endocytosis#GO:0006897;vesicle fusion#GO:0006906;cellular component organization#GO:0016043;cellular localization#GO:0051641;localization#GO:0051179;vacuole organization#GO:0007033;endosome to lysosome transport#GO:0008333;lysosomal transport#GO:0007041;organelle assembly#GO:0070925 lytic vacuole#GO:0000323;vacuole#GO:0005773;cytoplasm#GO:0005737;endomembrane system#GO:0012505;phagocytic vesicle#GO:0045335;late endosome#GO:0005770;membrane-bounded organelle#GO:0043227;endocytic vesicle#GO:0030139;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;vesicle#GO:0031982;lysosome#GO:0005764;intracellular vesicle#GO:0097708 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC115324442|UniProtKB=A0ACM8E3Y5 A0ACM8E3Y5 LOC115324442 PTHR45848:SF4 DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 FAMILY MEMBER DUAL SPECIFICITY PROTEIN PHOSPHATASE 12 phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;protein tyrosine/serine/threonine phosphatase activity#GO:0008138;catalytic activity#GO:0003824;phosphoric ester hydrolase activity#GO:0042578;catalytic activity, acting on a protein#GO:0140096;phosphoprotein phosphatase activity#GO:0004721;hydrolase activity#GO:0016787 protein phosphatase#PC00195 Oxidative stress response#P00046>MKP5#P01131 IXOSC|EnsemblGenome=LOC8038463|UniProtKB=A0ACM8E2V4 A0ACM8E2V4 PTHR23255:SF71 TRANSFORMING GROWTH FACTOR-BETA RECEPTOR TYPE I AND II RECEPTOR PROTEIN SERINE_THREONINE KINASE BABO signaling receptor activity#GO:0038023;kinase activity#GO:0016301;activin binding#GO:0048185;transferase activity#GO:0016740;protein-containing complex binding#GO:0044877;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;transmembrane receptor protein serine/threonine kinase activity#GO:0004675;transmembrane signaling receptor activity#GO:0004888;binding#GO:0005488;protein serine/threonine kinase activity#GO:0004674;transmembrane receptor protein kinase activity#GO:0019199;catalytic activity, acting on a protein#GO:0140096;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity#GO:0003824;molecular transducer activity#GO:0060089 signal transduction#GO:0007165;cellular process#GO:0009987;transforming growth factor beta receptor superfamily signaling pathway#GO:0141091;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;nervous system development#GO:0007399;cell surface receptor protein serine/threonine kinase signaling pathway#GO:0007178;developmental process#GO:0032502;cell surface receptor signaling pathway#GO:0007166;multicellular organism development#GO:0007275;response to endogenous stimulus#GO:0009719;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;response to growth factor#GO:0070848;regulation of cellular process#GO:0050794;signaling#GO:0023052;animal gross anatomical part developmental process#GO:0160108;activin receptor signaling pathway#GO:0032924;cell communication#GO:0007154;enzyme-linked receptor protein signaling pathway#GO:0007167;anatomical structure development#GO:0048856;cellular response to growth factor stimulus#GO:0071363;system development#GO:0048731 serine/threonine protein kinase complex#GO:1902554;protein kinase complex#GO:1902911;transferase complex, transferring phosphorus-containing groups#GO:0061695;transferase complex#GO:1990234;catalytic complex#GO:1902494;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944 serine/threonine protein kinase receptor#PC00205 Activin beta signaling pathway#P06210>BABO#P06231;MYO signaling pathway#P06215>BABO#P06310;TGF-beta signaling pathway#P00052>TGFbetareceptors#P01283;TGF-beta signaling pathway#P00052>TGFbetareceptor I#P01278;ALP23B signaling pathway#P06209>BABO#P06220;TGF-beta signaling pathway#P00052>TGFbetareceptor II#P01277;BMP/activin signaling pathway-drosophila#P06211>TGFbetaR I#P06241;Wnt signaling pathway#P00057>TGFbetaactivated Kinase-1#P01442 IXOSC|EnsemblGenome=LOC8037367|UniProtKB=A0ACM8FAU5 A0ACM8FAU5 Use1 PTHR13050:SF7 USE1-LIKE PROTEIN VESICLE TRANSPORT PROTEIN USE1 SNAP receptor activity#GO:0005484;molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674 Golgi vesicle transport#GO:0048193;transport#GO:0006810;cellular process#GO:0009987;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;establishment of localization#GO:0051234;vesicle-mediated transport#GO:0016192;localization#GO:0051179 membrane protein complex#GO:0098796;membrane#GO:0016020;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;SNARE complex#GO:0031201;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC8030154|UniProtKB=A0ACM8DRL9 A0ACM8DRL9 LOC8030154 PTHR46698:SF4 CROSSVEINLESS 2 VWFD DOMAIN-CONTAINING PROTEIN extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC8053971|UniProtKB=A0ACM8FXA0 A0ACM8FXA0 LOC8053971 PTHR23233:SF84 SAL-LIKE PROTEIN FI23031P1-RELATED DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248;DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC120842214|UniProtKB=A0ACM8EUD3 A0ACM8EUD3 LOC120842214 PTHR48586:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037939|UniProtKB=A0ACM8DNY6 A0ACM8DNY6 LOC8037939 PTHR15970:SF2 ELL-ASSOCIATED FACTOR EAF ELL-ASSOCIATED FACTOR EAF transcription elongation factor activity#GO:0003711;transcription regulator activity#GO:0140110 transcription by RNA polymerase II#GO:0006366;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;DNA-templated transcription elongation#GO:0006354;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;gene expression#GO:0010467;transcription elongation by RNA polymerase II#GO:0006368;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;DNA-templated transcription#GO:0006351;RNA biosynthetic process#GO:0032774 transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;protein-containing complex#GO:0032991;nucleus#GO:0005634;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 IXOSC|EnsemblGenome=LOC120850793|UniProtKB=A0ACM8FAT4 A0ACM8FAT4 LOC120850793 PTHR13026:SF0 NNP-1 PROTEIN NOVEL NUCLEAR PROTEIN 1 NOP52 RIBOSOMAL RNA PROCESSING 1B transcription coactivator activity#GO:0003713;transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromosome#GO:0005694;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC120850885|UniProtKB=A0ACM8FBB4 A0ACM8FBB4 PTHR46289:SF21 52 KDA REPRESSOR OF THE INHIBITOR OF THE PROTEIN KINASE-LIKE PROTEIN-RELATED HAT C-TERMINAL DIMERISATION DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039181|UniProtKB=A0ACM8DKB6 A0ACM8DKB6 DCP1 PTHR16290:SF0 TRANSCRIPTION FACTOR SMIF DECAPPING ENZYME DCP1 DECAPPING PROTEIN 1, ISOFORM A mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA decapping#GO:0110154;RNA metabolic process#GO:0016070;RNA catabolic process#GO:0006401;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;negative regulation of biological process#GO:0048519;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;nuclear-transcribed mRNA catabolic process#GO:0000956;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;nucleic acid catabolic process#GO:0141188;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;nucleobase-containing compound catabolic process#GO:0034655 P-body#GO:0000932;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytoplasmic ribonucleoprotein granule#GO:0036464;cellular anatomical structure#GO:0110165;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232 RNA processing factor#PC00147;mRNA capping factor#PC00145 TGF-beta signaling pathway#P00052>Co-activators corepressors#P01282 IXOSC|EnsemblGenome=LOC8038275|UniProtKB=A0ACM8EH86 A0ACM8EH86 Arp10 PTHR11937:SF14 ACTIN ACTIN-RELATED PROTEIN 10 structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;axo-dendritic transport#GO:0008088;organelle transport along microtubule#GO:0072384;cytoskeleton-dependent intracellular transport#GO:0030705;transport#GO:0006810;intracellular transport#GO:0046907;microtubule-based process#GO:0007017;mitochondrion localization#GO:0051646;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;microtubule-based transport#GO:0099111;retrograde axonal transport#GO:0008090;axonal transport#GO:0098930;organelle localization#GO:0051640;localization#GO:0051179;cellular localization#GO:0051641 intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;microtubule associated complex#GO:0005875;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226 actin and actin related protein#PC00039 IXOSC|EnsemblGenome=LOC8041376|UniProtKB=A0ACM8DMF6 A0ACM8DMF6 LOC8041376 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;symporter activity#GO:0015293 sodium ion transport#GO:0006814;transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115328531|UniProtKB=A0ACM8E887 A0ACM8E887 LOC115328531 PTHR15544:SF0 OSMOSIS RESPONSIVE FACTOR TETRATRICOPEPTIDE REPEAT PROTEIN 33 IXOSC|EnsemblGenome=LOC8026341|UniProtKB=A0ACM8DHM3 A0ACM8DHM3 LOC8026341 PTHR10797:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT POLY(A)-SPECIFIC RIBONUCLEASE catalytic activity#GO:0003824;catalytic activity, acting on a nucleic acid#GO:0140640;hydrolase activity, acting on ester bonds#GO:0016788;3'-5' exonuclease activity#GO:0008408;catalytic activity, acting on RNA#GO:0140098;RNA nuclease activity#GO:0004540;exonuclease activity#GO:0004527;3'-5'-RNA exonuclease activity#GO:0000175;hydrolase activity#GO:0016787;nuclease activity#GO:0004518 positive regulation of macromolecule metabolic process#GO:0010604;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA destabilization#GO:0050779;positive regulation of biological process#GO:0048518;cellular process#GO:0009987;regulation of mRNA metabolic process#GO:1903311;metabolic process#GO:0008152;mRNA destabilization#GO:0061157;positive regulation of mRNA metabolic process#GO:1903313;macromolecule catabolic process#GO:0009057;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;regulation of mRNA catabolic process#GO:0061013;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;positive regulation of metabolic process#GO:0009893;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;RNA catabolic process#GO:0006401;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;positive regulation of cellular process#GO:0048522;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay#GO:0000288;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;positive regulation of catabolic process#GO:0009896;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;catabolic process#GO:0009056;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;positive regulation of mRNA catabolic process#GO:0061014;regulation of RNA metabolic process#GO:0051252;regulation of RNA stability#GO:0043487 cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;organelle#GO:0043226;supramolecular complex#GO:0099080;ribonucleoprotein granule#GO:0035770;CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;P-body#GO:0000932 RNA metabolism protein#PC00031;mRNA polyadenylation factor#PC00146;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120836545|UniProtKB=A0ACM8EFW6 A0ACM8EFW6 LOC120836545 PTHR19991:SF3 L 2 01289 HULK, ISOFORM F IXOSC|EnsemblGenome=LOC115328755|UniProtKB=A0ACM8EPI3 A0ACM8EPI3 LOC115328755 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8029675|UniProtKB=A0ACM8EBQ6 A0ACM8EBQ6 LOC8029675 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8039287|UniProtKB=A0ACM8G250 A0ACM8G250 LOC8039287 PTHR46560:SF1 CYPHER, ISOFORM B DUSKY developmental process#GO:0032502;anatomical structure morphogenesis#GO:0009653;cell morphogenesis#GO:0000902;anatomical structure development#GO:0048856 membrane#GO:0016020;apical plasma membrane#GO:0016324;cell periphery#GO:0071944;apical part of cell#GO:0045177;cellular anatomical structure#GO:0110165;plasma membrane region#GO:0098590;plasma membrane#GO:0005886 IXOSC|EnsemblGenome=LOC8040734|UniProtKB=A0ACM8E0D7 A0ACM8E0D7 Bulli PTHR12897:SF4 COLON CANCER-ASSOCIATED PROTEIN MIC1 REGULATOR OF MON1-CCZ1 COMPLEX protein complex scaffold activity#GO:0140378;structural molecule activity#GO:0005198 regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of autophagy#GO:0010506;regulation of catabolic process#GO:0009894;biological regulation#GO:0065007;regulation of cellular process#GO:0050794 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;endosome membrane#GO:0010008;endosome#GO:0005768;intracellular organelle#GO:0043229;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;vesicle membrane#GO:0012506;cytoplasm#GO:0005737;guanyl-nucleotide exchange factor complex#GO:0032045;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;late endosome#GO:0005770;late endosome membrane#GO:0031902;bounding membrane of organelle#GO:0098588;intracellular protein-containing complex#GO:0140535;organelle membrane#GO:0031090 IXOSC|EnsemblGenome=LOC120841461|UniProtKB=A0ACM8ERJ5 A0ACM8ERJ5 LOC120841461 PTHR22846:SF42 WD40 REPEAT PROTEIN SUBFAMILY NOT NAMED binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;transcription coregulator activity#GO:0003712;transcription corepressor activity#GO:0003714;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 negative regulation of cellular process#GO:0048523;negative regulation of RNA metabolic process#GO:0051253;negative regulation of RNA biosynthetic process#GO:1902679;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;regulation of nucleobase-containing compound metabolic process#GO:0019219;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;negative regulation of biosynthetic process#GO:0009890;negative regulation of DNA-templated transcription#GO:0045892;regulation of DNA-templated transcription#GO:0006355;negative regulation of transcription by RNA polymerase II#GO:0000122;negative regulation of nucleobase-containing compound metabolic process#GO:0045934;regulation of RNA metabolic process#GO:0051252;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;negative regulation of metabolic process#GO:0009892 protein-containing complex#GO:0032991;membrane-enclosed lumen#GO:0031974;histone deacetylase complex#GO:0000118;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;transcription regulator complex#GO:0005667;transcription repressor complex#GO:0017053;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;nucleoplasm#GO:0005654;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494 IXOSC|EnsemblGenome=LOC8028838|UniProtKB=A0ACM8DTL7 A0ACM8DTL7 LOC8028838 PTHR16212:SF4 FOCADHESIN FAMILY MEMBER FOCADHESIN IXOSC|EnsemblGenome=LOC121832901|UniProtKB=A0ACM8FPA5 A0ACM8FPA5 LOC121832901 PTHR12042:SF21 LACTOSYLCERAMIDE 4-ALPHA-GALACTOSYLTRANSFERASE ALPHA- 1,4-GALACTOSYLTRANSFERASE ALPHA 1,4-GLYCOSYLTRANSFERASE DOMAIN-CONTAINING PROTEIN transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 liposaccharide metabolic process#GO:1903509;glycolipid metabolic process#GO:0006664;lipid biosynthetic process#GO:0008610;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;glycolipid biosynthetic process#GO:0009247;carbohydrate derivative biosynthetic process#GO:1901137;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;glycosphingolipid biosynthetic process#GO:0006688;lipid metabolic process#GO:0006629 metabolite interconversion enzyme#PC00262;transferase#PC00220 IXOSC|EnsemblGenome=LOC8051405|UniProtKB=A0ACM8F4H2 A0ACM8F4H2 LOC8051405 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;chitinase activity#GO:0004568;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152;carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115332981|UniProtKB=A0ACM8FUT6 A0ACM8FUT6 LOC115332981 PTHR10177:SF615 CYCLINS G2_MITOTIC-SPECIFIC CYCLIN-A enzyme regulator activity#GO:0030234;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 mitotic cell cycle#GO:0000278;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;cell cycle G1/S phase transition#GO:0044843;cell cycle process#GO:0022402;cellular process#GO:0009987;mitotic cell cycle process#GO:1903047;mitotic cell cycle phase transition#GO:0044772;G1/S transition of mitotic cell cycle#GO:0000082 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;transferase complex, transferring phosphorus-containing groups#GO:0061695;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transferase complex#GO:1990234;microtubule organizing center#GO:0005815;cytoskeleton#GO:0005856;protein kinase complex#GO:1902911;membraneless organelle#GO:0043228;nucleus#GO:0005634;microtubule cytoskeleton#GO:0015630;cyclin-dependent protein kinase holoenzyme complex#GO:0000307;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991 kinase activator#PC00138 IXOSC|EnsemblGenome=LOC120837171|UniProtKB=A0ACM8EGR5 A0ACM8EGR5 LOC120837171 PTHR24381:SF486 ZINC FINGER PROTEIN ADULT ENHANCER FACTOR 1-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;nucleic acid binding#GO:0003676;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8035572|UniProtKB=A0ACM8DRH2 A0ACM8DRH2 LOC8035572 PTHR23345:SF15 VITELLOGENIN-RELATED VITELLOGENIN-6 lipid carrier activity#GO:0005319;molecular carrier activity#GO:0140104 storage protein#PC00210 IXOSC|EnsemblGenome=LOC8033274|UniProtKB=A0ACM8DHL2 A0ACM8DHL2 Ppa PTHR13318:SF190 PARTNER OF PAIRED, ISOFORM B-RELATED PARTNER OF PAIRED, ISOFORM B primary metabolic process#GO:0044238;cellular process#GO:0009987;modification-dependent protein catabolic process#GO:0019941;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;SCF-dependent proteasomal ubiquitin-dependent protein catabolic process#GO:0031146;metabolic process#GO:0008152;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;ubiquitin-dependent protein catabolic process#GO:0006511 cullin-RING ubiquitin ligase complex#GO:0031461;intracellular protein-containing complex#GO:0140535;SCF ubiquitin ligase complex#GO:0019005;ubiquitin ligase complex#GO:0000151;protein-containing complex#GO:0032991;catalytic complex#GO:1902494;transferase complex#GO:1990234 IXOSC|EnsemblGenome=LOC121837432|UniProtKB=A0ACM8G4L2 A0ACM8G4L2 LOC121837432 PTHR14628:SF2 BEN DOMAIN-CONTAINING PROTEIN 5 BEN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120841721|UniProtKB=A0ACM8ERX7 A0ACM8ERX7 LOC120841721 PTHR45620:SF44 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTOR, ORPHAN-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled peptide receptor activity#GO:0008528;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;signaling receptor activity#GO:0038023 signal transduction#GO:0007165;regulation of biological process#GO:0050789;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signaling#GO:0023052;biological regulation#GO:0065007;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8043944|UniProtKB=A0ACM8FX36 A0ACM8FX36 qsm PTHR47327:SF7 FI18240P1-RELATED GH08941P anatomical structure morphogenesis#GO:0009653;developmental process#GO:0032502;anatomical structure development#GO:0048856 IXOSC|EnsemblGenome=LOC8038894|UniProtKB=A0ACM8EDK3 A0ACM8EDK3 LOC8038894 PTHR24291:SF189 CYTOCHROME P450 FAMILY 4 CYTOCHROME P450 4V2 oxidoreductase#PC00176;oxygenase#PC00177;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034513|UniProtKB=A0ACM8E8X0 A0ACM8E8X0 LOC8034513 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8032064|UniProtKB=A0ACM8EIA0 A0ACM8EIA0 LOC8032064 PTHR47735:SF14 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1 monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;transporter activity#GO:0005215;voltage-gated channel activity#GO:0022832;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated monoatomic ion channel activity#GO:0005244;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;monoatomic cation channel activity#GO:0005261;passive transmembrane transporter activity#GO:0022803;transmembrane transporter activity#GO:0022857;potassium ion transmembrane transporter activity#GO:0015079;channel activity#GO:0015267;potassium channel activity#GO:0005267 monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;monoatomic cation transport#GO:0006812;localization#GO:0051179;transport#GO:0006810;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transmembrane transport#GO:0071805;potassium ion transport#GO:0006813;cellular process#GO:0009987 plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane#GO:0016020;membrane protein complex#GO:0098796;transporter complex#GO:1990351;transmembrane transporter complex#GO:1902495;voltage-gated potassium channel complex#GO:0008076;cation channel complex#GO:0034703 voltage-gated ion channel#PC00241;transporter#PC00227 IXOSC|EnsemblGenome=LOC8033981|UniProtKB=A0ACM8DIR1 A0ACM8DIR1 LOC8033981 PTHR11164:SF0 GLUTAMATE CYSTEINE LIGASE GLUTAMATE--CYSTEINE LIGASE CATALYTIC SUBUNIT ligase activity, forming carbon-nitrogen bonds#GO:0016879;catalytic activity#GO:0003824;ligase activity#GO:0016874 peptide metabolic process#GO:0006518;biosynthetic process#GO:0009058;cellular process#GO:0009987;glutathione metabolic process#GO:0006749;modified amino acid metabolic process#GO:0006575;sulfur compound metabolic process#GO:0006790;metabolic process#GO:0008152 catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 metabolite interconversion enzyme#PC00262;ligase#PC00142 IXOSC|EnsemblGenome=LOC115314584|UniProtKB=A0ACM8FDV8 A0ACM8FDV8 LOC115314584 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC8052660|UniProtKB=A0ACM8EBS8 A0ACM8EBS8 LOC8052660 PTHR11610:SF200 LIPASE FI22312P1 hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity#GO:0016787 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 IXOSC|EnsemblGenome=LOC120840910|UniProtKB=A0ACM8EQC8 A0ACM8EQC8 LOC120840910 PTHR42760:SF83 SHORT-CHAIN DEHYDROGENASES/REDUCTASES FAMILY MEMBER (3R)-3-HYDROXYACYL-COA DEHYDROGENASE-RELATED oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;catalytic activity#GO:0003824;small molecule binding#GO:0036094;binding#GO:0005488;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616 primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid biosynthetic process#GO:0046394;cellular process#GO:0009987;lipid biosynthetic process#GO:0008610;small molecule metabolic process#GO:0044281;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;fatty acid metabolic process#GO:0006631;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;monocarboxylic acid biosynthetic process#GO:0072330 oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC120836995|UniProtKB=A0ACM8EH03 A0ACM8EH03 LOC120836995 PTHR47163:SF5 DDE_TNP_IS1595 DOMAIN-CONTAINING PROTEIN ISXO2-LIKE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115331995|UniProtKB=A0ACM8ED68 A0ACM8ED68 LOC115331995 PTHR24409:SF449 ZINC FINGER PROTEIN 142 AT31036P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120837863|UniProtKB=A0ACM8EHZ9 A0ACM8EHZ9 LOC120837863 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115332163|UniProtKB=A0ACM8EE94 A0ACM8EE94 LRP1 PTHR24270:SF8 LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED VITELLOGENIN RECEPTOR YL membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transfer/carrier protein#PC00219;apolipoprotein#PC00052 IXOSC|EnsemblGenome=LOC120839757|UniProtKB=A0ACM8EM22 A0ACM8EM22 LOC120839757 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC120836664|UniProtKB=A0ACM8FQI7 A0ACM8FQI7 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8043623|UniProtKB=A0ACM8DUP5 A0ACM8DUP5 LOC8043623 PTHR12345:SF16 SYNTENIN RELATED X11L, ISOFORM F-RELATED anterograde trans-synaptic signaling#GO:0098916;biological regulation#GO:0065007;signaling#GO:0023052;cell-cell signaling#GO:0007267;chemical synaptic transmission#GO:0007268;synaptic signaling#GO:0099536;regulation of biological process#GO:0050789;cellular process#GO:0009987;cell communication#GO:0007154;trans-synaptic signaling#GO:0099537 intracellular anatomical structure#GO:0005622;dendritic tree#GO:0097447;dendrite#GO:0030425;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;neuron spine#GO:0044309;cellular anatomical structure#GO:0110165;synapse#GO:0045202;dendritic spine#GO:0043197;postsynapse#GO:0098794;cell junction#GO:0030054;somatodendritic compartment#GO:0036477;plasma membrane#GO:0005886;cytoplasm#GO:0005737;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020 membrane trafficking regulatory protein#PC00151;membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115328605|UniProtKB=A0ACM8EHC5 A0ACM8EHC5 LOC115328605 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;metalloendopeptidase activity#GO:0004222 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115331589|UniProtKB=A0ACM8ECM7 A0ACM8ECM7 LOC115331589 PTHR24394:SF71 ZINC FINGER PROTEIN ZINC FINGER PROTEIN 791 DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;transcription regulator activity#GO:0140110;DNA-binding transcription factor activity#GO:0003700 regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8044062|UniProtKB=A0ACM8DZB5 A0ACM8DZB5 Not11 PTHR15975:SF0 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 11 regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;post-transcriptional regulation of gene expression#GO:0010608 CCR4-NOT complex#GO:0030014;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991 IXOSC|EnsemblGenome=LOC8043509|UniProtKB=A0ACM8DZM8 A0ACM8DZM8 LOC8043509 PTHR11731:SF200 PROTEASE FAMILY S9B,C DIPEPTIDYL-PEPTIDASE IV-RELATED VENOM DIPEPTIDYL PEPTIDASE 4 exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120836650|UniProtKB=A0ACM8EG41 A0ACM8EG41 LOC120836650 PTHR19424:SF0 HEAT SHOCK FACTOR BINDING PROTEIN 1 HEAT SHOCK FACTOR-BINDING PROTEIN 1 cellular response to stress#GO:0033554;response to stress#GO:0006950;response to abiotic stimulus#GO:0009628;response to heat#GO:0009408;cellular response to heat#GO:0034605;heat acclimation#GO:0010286;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;response to temperature stimulus#GO:0009266 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;nucleus#GO:0005634 IXOSC|EnsemblGenome=LOC8035297|UniProtKB=A0ACM8DZA2 A0ACM8DZA2 LOC8035297 PTHR21196:SF1 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 U7 SNRNA-ASSOCIATED SM-LIKE PROTEIN LSM10 RNA binding#GO:0003723;snRNA binding#GO:0017069;binding#GO:0005488;nucleic acid binding#GO:0003676 metabolic process#GO:0008152;mRNA 3'-end processing#GO:0031124;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;mRNA processing#GO:0006397;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774 membraneless organelle#GO:0043228;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;nuclear body#GO:0016604;intracellular membraneless organelle#GO:0043232;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;cytoplasmic ribonucleoprotein granule#GO:0036464;nucleoplasm#GO:0005654;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC120836266|UniProtKB=A0ACM8F9S4 A0ACM8F9S4 LOC120836266 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC121834077|UniProtKB=A0ACM8FQ29 A0ACM8FQ29 PTHR47501:SF10 TRANSPOSASE-RELATED DUF659 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115309092|UniProtKB=A0ACM8EWT4 A0ACM8EWT4 LOC115309092 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8050626|UniProtKB=A0ACM8DTD1 A0ACM8DTD1 Rpn3 PTHR10758:SF2 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3/COP9 SIGNALOSOME COMPLEX SUBUNIT 3 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 3 primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;proteasome regulatory particle, lid subcomplex#GO:0008541;endopeptidase complex#GO:1905369;catalytic complex#GO:1902494;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;peptidase complex#GO:1905368;proteasome complex#GO:0000502 protein modifying enzyme#PC00260;protease#PC00190 Cell cycle#P00013>Proteasome#P00480;Ubiquitin proteasome pathway#P00060>26S proteasome#P01489 IXOSC|EnsemblGenome=LOC115311616|UniProtKB=A0ACM8FUM1 A0ACM8FUM1 dtn PTHR13388:SF11 DETONATOR, ISOFORM E DETONATOR, ISOFORM E cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115314317|UniProtKB=A0ACM8FVI6 A0ACM8FVI6 LOC115314317 PTHR31569:SF7 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZSWIM1_3 RNASEH-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039305|UniProtKB=A0ACM8DKB8 A0ACM8DKB8 LOC8039305 PTHR22133:SF2 AT01821P-RELATED AT01821P-RELATED IXOSC|EnsemblGenome=LOC8042217|UniProtKB=A0ACM8G8D8 A0ACM8G8D8 LOC8042217 PTHR23293:SF9 FAD SYNTHETASE-RELATED FMN ADENYLYLTRANSFERASE BIFUNCTIONAL FAD DIPHOSPHATASE_FAD SYNTHASE adenylyltransferase activity#GO:0070566;transferase activity, transferring phosphorus-containing groups#GO:0016772;nucleotidyltransferase activity#GO:0016779;catalytic activity#GO:0003824;transferase activity#GO:0016740 organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;nucleoside phosphate biosynthetic process#GO:1901293;nucleobase-containing small molecule metabolic process#GO:0055086;flavin-containing compound metabolic process#GO:0042726;phosphorus metabolic process#GO:0006793;primary metabolic process#GO:0044238;small molecule metabolic process#GO:0044281;nucleoside phosphate metabolic process#GO:0006753;nucleotide metabolic process#GO:0009117;organophosphate biosynthetic process#GO:0090407;nucleotide biosynthetic process#GO:0009165 transferase#PC00220;metabolite interconversion enzyme#PC00262 Flavin biosynthesis#P02741>FAD synthetase#P02936 IXOSC|EnsemblGenome=LOC8038226|UniProtKB=A0ACM8E8F1 A0ACM8E8F1 LOC8038226 PTHR24289:SF24 STEROID 17-ALPHA-HYDROXYLASE/17,20 LYASE STEROID 21-HYDROXYLASE catalytic activity#GO:0003824;steroid hydroxylase activity#GO:0008395;monooxygenase activity#GO:0004497;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;oxidoreductase activity#GO:0016491;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen#GO:0016712 regulation of biological quality#GO:0065008;olefinic compound metabolic process#GO:0120254;metabolic process#GO:0008152;lipid metabolic process#GO:0006629;hormone metabolic process#GO:0042445;biosynthetic process#GO:0009058;hormone biosynthetic process#GO:0042446;biological regulation#GO:0065007;steroid metabolic process#GO:0008202;ketone metabolic process#GO:0042180;primary metabolic process#GO:0044238;cellular process#GO:0009987;regulation of hormone levels#GO:0010817 IXOSC|EnsemblGenome=LOC115311766|UniProtKB=A0ACM8DRA3 A0ACM8DRA3 LOC115311766 PTHR15572:SF0 GLIOMA TUMOR SUPPRESSOR CANDIDATE REGION GENE 1 BRD4 INTERACTING CHROMATIN REMODELING COMPLEX ASSOCIATED PROTEIN, ISOFORM B positive regulation of RNA metabolic process#GO:0051254;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of RNA metabolic process#GO:0051252;positive regulation of metabolic process#GO:0009893;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of DNA-templated transcription#GO:0006355;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of DNA-templated transcription#GO:0045893;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889 SWI/SNF superfamily-type complex#GO:0070603;chromosome#GO:0005694;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;ATPase complex#GO:1904949;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;SWI/SNF complex#GO:0016514;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;chromatin#GO:0000785;nucleus#GO:0005634;intracellular membraneless organelle#GO:0043232;protein-containing complex#GO:0032991;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513 IXOSC|EnsemblGenome=LOC8027961|UniProtKB=A0ACM8DJI7 A0ACM8DJI7 RpL35 PTHR45722:SF2 60S RIBOSOMAL PROTEIN L35 LARGE RIBOSOMAL SUBUNIT PROTEIN UL29 structural molecule activity#GO:0005198;RNA binding#GO:0003723;mRNA binding#GO:0003729;binding#GO:0005488;nucleic acid binding#GO:0003676;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;rRNA metabolic process#GO:0016072;nucleobase-containing compound biosynthetic process#GO:0034654;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;cellular component biogenesis#GO:0044085;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;maturation of LSU-rRNA#GO:0000470;gene expression#GO:0010467;biosynthetic process#GO:0009058;maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000463;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;ribosomal large subunit biogenesis#GO:0042273;ribosome biogenesis#GO:0042254;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;rRNA processing#GO:0006364;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;ribonucleoprotein complex biogenesis#GO:0022613 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8052265|UniProtKB=A0ACM8DVK9 A0ACM8DVK9 LOC8052265 PTHR10131:SF165 TNF RECEPTOR ASSOCIATED FACTOR E3 UBIQUITIN-PROTEIN LIGASE NRDP1 regulation of canonical NF-kappaB signal transduction#GO:0043122;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;regulation of response to stimulus#GO:0048583 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8031857|UniProtKB=A0ACM8FRT9 A0ACM8FRT9 LOC8031857 PTHR23279:SF36 DEFECTIVE PROBOSCIS EXTENSION RESPONSE DPR -RELATED DEFECTIVE PROBOSCIS EXTENSION RESPONSE 8, ISOFORM A synapse organization#GO:0050808;cellular process#GO:0009987;cellular component organization#GO:0016043;cellular component organization or biogenesis#GO:0071840;cell junction organization#GO:0034330 neuron projection#GO:0043005;cell periphery#GO:0071944;cell leading edge#GO:0031252;membrane#GO:0016020;cell projection#GO:0042995;plasma membrane#GO:0005886;plasma membrane bounded cell projection#GO:0120025;plasma membrane region#GO:0098590;cellular anatomical structure#GO:0110165;leading edge membrane#GO:0031256;neuron projection membrane#GO:0032589;cell projection membrane#GO:0031253 IXOSC|EnsemblGenome=LOC120846093|UniProtKB=A0ACM8FK82 A0ACM8FK82 LOC120846093 PTHR24384:SF189 FINGER PUTATIVE TRANSCRIPTION FACTOR FAMILY-RELATED C2H2-TYPE DOMAIN-CONTAINING PROTEIN-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC121835316|UniProtKB=A0ACM8FTU6 A0ACM8FTU6 LOC121835316 PTHR11177:SF410 CHITINASE HISTIDINE-RICH CARBOXYL TERMINUS PROTEIN 1 ISOFORM X1 hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 chitin metabolic process#GO:0006030;metabolic process#GO:0008152;aminoglycan metabolic process#GO:0006022;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;carbohydrate derivative catabolic process#GO:1901136;catabolic process#GO:0009056;amino sugar metabolic process#GO:0006040 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC115326667|UniProtKB=A0ACM8ES28 A0ACM8ES28 LOC115326667 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC8031149|UniProtKB=A0ACM8ED22 A0ACM8ED22 LOC8031149 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC115323868|UniProtKB=A0ACM8E4E6 A0ACM8E4E6 LOC115323868 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;proteolysis#GO:0006508;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8042256|UniProtKB=A0ACM8FLA4 A0ACM8FLA4 LOC8042256 PTHR11088:SF89 TRNA DIMETHYLALLYLTRANSFERASE TRNA DIMETHYLALLYLTRANSFERASE catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on RNA#GO:0140098;transferase activity, transferring alkyl or aryl (other than methyl) groups#GO:0016765;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on a nucleic acid#GO:0140640 gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;metabolic process#GO:0008152;tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;macromolecule modification#GO:0043412;RNA metabolic process#GO:0016070;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8039478|UniProtKB=A0ACM8FXY6 A0ACM8FXY6 LOC8039478 PTHR10201:SF338 MATRIX METALLOPROTEINASE MATRIX METALLOPROTEINASE 2 metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096 catabolic process#GO:0009056;cellular component organization#GO:0016043;cellular process#GO:0009987;extracellular matrix organization#GO:0030198;cellular component organization or biogenesis#GO:0071840;external encapsulating structure organization#GO:0045229;extracellular structure organization#GO:0043062;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8030291|UniProtKB=A0ACM8DGK5 A0ACM8DGK5 LOC8030291 PTHR12441:SF10 ATP SYNTHASE COUPLING FACTOR 6, MITOCHONDRIAL ATP SYNTHASE PERIPHERAL STALK SUBUNIT F6, MITOCHONDRIAL membrane protein complex#GO:0098796;membrane#GO:0016020;respiratory chain complex#GO:0098803;proton-transporting ATP synthase complex#GO:0045259;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;monoatomic ion channel complex#GO:0034702;catalytic complex#GO:1902494;cation channel complex#GO:0034703;proton-transporting two-sector ATPase complex#GO:0016469;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351 primary active transporter#PC00068;ATP synthase#PC00002 IXOSC|EnsemblGenome=LOC8028164|UniProtKB=A0ACM8FUC6 A0ACM8FUC6 LOC8028164 PTHR37984:SF18 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115317852|UniProtKB=A0ACM8DY23 A0ACM8DY23 LOC115317852 PTHR11214:SF411 BETA-1,3-N-ACETYLGLUCOSAMINYLTRANSFERASE HEXOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;catalytic activity#GO:0003824;transferase activity#GO:0016740 bounding membrane of organelle#GO:0098588;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090;membrane-bounded organelle#GO:0043227;Golgi membrane#GO:0000139;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC115317680|UniProtKB=A0ACM8EKD5 A0ACM8EKD5 LOC115317680 PTHR10010:SF46 SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN 2B secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115326296|UniProtKB=A0ACM8E5Q8 A0ACM8E5Q8 Dnz1 PTHR12246:SF23 PALMITOYLTRANSFERASE ZDHHC16 PALMITOYLTRANSFERASE palmitoyltransferase activity#GO:0016409;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747;transferase activity#GO:0016740;catalytic activity#GO:0003824;acyltransferase activity#GO:0016746 protein modifying enzyme#PC00260 IXOSC|EnsemblGenome=LOC8042528|UniProtKB=A0ACM8E555 A0ACM8E555 Chmp1 PTHR10476:SF2 CHARGED MULTIVESICULAR BODY PROTEIN CHARGED MULTIVESICULAR BODY PROTEIN 1B-RELATED late endosome to vacuole transport#GO:0045324;protein transport#GO:0015031;localization#GO:0051179;cellular localization#GO:0051641;endosome transport via multivesicular body sorting pathway#GO:0032509;vesicle-mediated transport#GO:0016192;establishment of localization in cell#GO:0051649;establishment of protein localization#GO:0045184;multivesicular body sorting pathway#GO:0071985;cellular process#GO:0009987;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;endosomal transport#GO:0016197;establishment of localization#GO:0051234;vacuolar transport#GO:0007034;transport#GO:0006810;intracellular transport#GO:0046907 bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;protein-containing complex#GO:0032991;late endosome#GO:0005770;cytoplasmic vesicle membrane#GO:0030659;endomembrane system#GO:0012505;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;membrane protein complex#GO:0098796;intracellular vesicle#GO:0097708;vesicle#GO:0031982 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC120846650|UniProtKB=A0ACM8FG40 A0ACM8FG40 LOC120846650 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC115327220|UniProtKB=A0ACM8G7N4 A0ACM8G7N4 LOC115327220 PTHR24393:SF176 ZINC FINGER PROTEIN IP01243P-RELATED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulatory region nucleic acid binding#GO:0001067;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8051411|UniProtKB=A0ACM8DS37 A0ACM8DS37 LOC8051411 PTHR13115:SF8 RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG RNA POLYMERASE-ASSOCIATED PROTEIN RTF1 HOMOLOG enzyme binding#GO:0019899;RNA polymerase binding#GO:0070063;binding#GO:0005488;RNA polymerase core enzyme binding#GO:0043175;RNA polymerase II complex binding#GO:0000993;protein binding#GO:0005515 regulation of gene expression#GO:0010468;cellular component organization or biogenesis#GO:0071840;regulation of biosynthetic process#GO:0009889;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;chromatin organization#GO:0006325;regulation of nucleobase-containing compound metabolic process#GO:0019219;cellular process#GO:0009987;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;cellular component organization#GO:0016043 transferase complex#GO:1990234;Cdc73/Paf1 complex#GO:0016593;intracellular protein-containing complex#GO:0140535;nuclear protein-containing complex#GO:0140513;RNA polymerase complex#GO:0030880;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;protein-containing complex#GO:0032991;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;DNA-directed RNA polymerase complex#GO:0000428;intracellular anatomical structure#GO:0005622;RNA polymerase II, holoenzyme#GO:0016591;nuclear DNA-directed RNA polymerase complex#GO:0055029;organelle lumen#GO:0043233;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981 IXOSC|EnsemblGenome=LOC8039593|UniProtKB=A0ACM8DKD8 A0ACM8DKD8 LOC8039593 PTHR12307:SF36 PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT enzyme binding#GO:0019899;phosphatase binding#GO:0019902;polysaccharide binding#GO:0030247;binding#GO:0005488;protein phosphatase binding#GO:0019903;protein binding#GO:0005515;carbohydrate binding#GO:0030246 biological regulation#GO:0065007;regulation of carbohydrate biosynthetic process#GO:0043255;regulation of polysaccharide metabolic process#GO:0032881;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biosynthetic process#GO:0009889;regulation of polysaccharide biosynthetic process#GO:0032885;regulation of glycogen biosynthetic process#GO:0005979;regulation of carbohydrate metabolic process#GO:0006109 protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;catalytic complex#GO:1902494;protein serine/threonine phosphatase complex#GO:0008287 phosphatase modulator#PC00184;protein-binding activity modulator#PC00095 IXOSC|EnsemblGenome=LOC120850258|UniProtKB=A0ACM8F8E6 A0ACM8F8E6 LOC120850258 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120836849|UniProtKB=A0ACM8G7R3 A0ACM8G7R3 LOC120836849 PTHR31569:SF8 SWIM-TYPE DOMAIN-CONTAINING PROTEIN MI DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8029989|UniProtKB=A0ACM8DJ41 A0ACM8DJ41 LOC8029989 PTHR43831:SF1 ISOBUTYRYL-COA DEHYDROGENASE ISOBUTYRYL-COA DEHYDROGENASE, MITOCHONDRIAL oxidoreductase activity, acting on the CH-CH group of donors#GO:0016627;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;proteinogenic amino acid metabolic process#GO:0170039;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC120843709|UniProtKB=A0ACM8EWS5 A0ACM8EWS5 LOC120843709 PTHR46609:SF10 EXONUCLEASE, PHAGE-TYPE/RECB, C-TERMINAL DOMAIN-CONTAINING PROTEIN YQAJ VIRAL RECOMBINASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308187|UniProtKB=A0ACM8E425 A0ACM8E425 LOC115308187 PTHR12370:SF3 N-TERMINAL NUCLEOPHILE (NTN) HYDROLASE AMINOPEPTIDASE PLBD2-RELATED cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 phospholipase#PC00186 IXOSC|EnsemblGenome=LOC8023264|UniProtKB=A0ACM8F4A6 A0ACM8F4A6 LOC8023264 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787 small molecule metabolic process#GO:0044281;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC8054024|UniProtKB=A0ACM8DLN0 A0ACM8DLN0 BckdhA PTHR43380:SF1 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule metabolic process#GO:0044281;catabolic process#GO:0009056;small molecule catabolic process#GO:0044282;amino acid metabolic process#GO:0006520;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987;carboxylic acid catabolic process#GO:0046395 protein-containing complex#GO:0032991;oxidoreductase complex#GO:1990204;transferase complex#GO:1990234;catalytic complex#GO:1902494 oxidoreductase#PC00176;dehydrogenase#PC00092 IXOSC|EnsemblGenome=LOC8034124|UniProtKB=A0ACM8DIY9 A0ACM8DIY9 LOC8034124 PTHR12277:SF204 ALPHA/BETA HYDROLASE DOMAIN-CONTAINING PROTEIN PALMITOYL-PROTEIN HYDROLASE hydrolase activity#GO:0016787;palmitoyl hydrolase activity#GO:0098599;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824;thiolester hydrolase activity#GO:0016790;hydrolase activity, acting on ester bonds#GO:0016788 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;vesicle#GO:0031982;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;endosome#GO:0005768;endosome membrane#GO:0010008;intracellular organelle#GO:0043229;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;vesicle membrane#GO:0012506;cell periphery#GO:0071944;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090 serine protease#PC00203 IXOSC|EnsemblGenome=LOC8027023|UniProtKB=A0ACM8DIL3 A0ACM8DIL3 LOC8027023 PTHR13353:SF5 TRANSMEMBRANE PROTEIN 19 TRANSMEMBRANE PROTEIN 19 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8031529|UniProtKB=A0ACM8E857 A0ACM8E857 LOC8031529 PTHR10694:SF129 LYSINE-SPECIFIC DEMETHYLASE LYSINE-SPECIFIC DEMETHYLASE 4B-RELATED histone modifying activity#GO:0140993;dioxygenase activity#GO:0051213;catalytic activity, acting on a protein#GO:0140096;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706;demethylase activity#GO:0032451;protein demethylase activity#GO:0140457;oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;histone demethylase activity#GO:0032452;catalytic activity#GO:0003824 regulation of biosynthetic process#GO:0009889;cellular component organization or biogenesis#GO:0071840;regulation of gene expression#GO:0010468;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular component organization#GO:0016043;cellular process#GO:0009987;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;chromatin remodeling#GO:0006338;chromatin organization#GO:0006325;biological regulation#GO:0065007 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694 histone modifying enzyme#PC00261 IXOSC|EnsemblGenome=LOC8051530|UniProtKB=A0ACM8DLF7 A0ACM8DLF7 LOC8051530 PTHR11106:SF123 GANGLIOSIDE INDUCED DIFFERENTIATION ASSOCIATED PROTEIN 2-RELATED MACRO DOMAIN-CONTAINING PROTEIN hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798;catalytic activity, acting on a protein#GO:0140096;catalytic activity#GO:0003824 nucleobase-containing small molecule metabolic process#GO:0055086;purine nucleoside metabolic process#GO:0042278;cellular response to stress#GO:0033554;DNA damage response#GO:0006974;metabolic process#GO:0008152;nucleobase-containing compound metabolic process#GO:0006139;nucleoside metabolic process#GO:0009116;small molecule metabolic process#GO:0044281;response to stimulus#GO:0050896;purine-containing compound metabolic process#GO:0072521;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;response to stress#GO:0006950;primary metabolic process#GO:0044238 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nucleoplasm#GO:0005654;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233 IXOSC|EnsemblGenome=LOC115328619|UniProtKB=A0ACM8E9T1 A0ACM8E9T1 LOC115328619 PTHR13385:SF0 AUTOPHAGY PROTEIN 12 UBIQUITIN-LIKE PROTEIN ATG12 aminoacyltransferase activity#GO:0016755;ubiquitin-like protein ligase activity#GO:0061659;catalytic activity, acting on a protein#GO:0140096;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;transferase activity#GO:0016740;catalytic activity#GO:0003824 organelle assembly#GO:0070925;energy reserve metabolic process#GO:0006112;vacuole organization#GO:0007033;glycogen metabolic process#GO:0005977;primary metabolic process#GO:0044238;protein-containing complex disassembly#GO:0032984;carbohydrate metabolic process#GO:0005975;piecemeal microautophagy of the nucleus#GO:0034727;catabolic process#GO:0009056;generation of precursor metabolites and energy#GO:0006091;autophagy of mitochondrion#GO:0000422;autophagosome maturation#GO:0097352;macromolecule metabolic process#GO:0043170;energy derivation by oxidation of organic compounds#GO:0015980;glycogen catabolic process#GO:0005980;macroautophagy#GO:0016236;process utilizing autophagic mechanism#GO:0061919;carbohydrate catabolic process#GO:0016052;cellular component disassembly#GO:0022411;polysaccharide catabolic process#GO:0000272;glucan metabolic process#GO:0044042;cellular component organization#GO:0016043;glucan catabolic process#GO:0009251;polysaccharide metabolic process#GO:0005976;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;autophagosome assembly#GO:0000045;protein-containing complex organization#GO:0043933;cellular component organization or biogenesis#GO:0071840;autophagy#GO:0006914;cellular process#GO:0009987;autophagosome organization#GO:1905037;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular component assembly#GO:0022607 autophagosome#GO:0005776;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;autophagosome membrane#GO:0000421;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;phagophore assembly site#GO:0000407;transferase complex#GO:1990234;vacuolar membrane#GO:0005774;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;membrane#GO:0016020;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vacuole#GO:0005773 IXOSC|EnsemblGenome=LOC120837776|UniProtKB=A0ACM8FK11 A0ACM8FK11 Nf-YC PTHR10252:SF156 HISTONE-LIKE TRANSCRIPTION FACTOR CCAAT-RELATED NUCLEAR TRANSCRIPTION FACTOR Y SUBUNIT GAMMA sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978 regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;transcription regulator complex#GO:0005667;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;RNA polymerase II transcription regulator complex#GO:0090575;nucleus#GO:0005634 DNA-binding transcription factor#PC00218 Gonadotropin-releasing hormone receptor pathway#P06664>NF-Y#P06742 IXOSC|EnsemblGenome=LOC115324598|UniProtKB=A0ACM8F881 A0ACM8F881 LOC115324598 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED active transmembrane transporter activity#GO:0022804;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291 transport#GO:0006810;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115311982|UniProtKB=A0ACM8DRQ1 A0ACM8DRQ1 LOC115311982 PTHR24252:SF7 ACROSIN-RELATED LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-LIKE ISOFORM X1 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC115316688|UniProtKB=A0ACM8DW80 A0ACM8DW80 LOC115316688 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;proteolysis#GO:0006508;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8039264|UniProtKB=A0ACM8EFL0 A0ACM8EFL0 LOC8039264 PTHR10404:SF84 N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG peptidase activity#GO:0008233;carboxypeptidase activity#GO:0004180;exopeptidase activity#GO:0008238;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115332250|UniProtKB=A0ACM8G7Y0 A0ACM8G7Y0 LOC115332250 PTHR22930:SF308 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC8051529|UniProtKB=A0ACM8E8G9 A0ACM8E8G9 LOC8051529 PTHR13962:SF22 FORKHEAD BOX PROTEIN N3-LIKE PROTEIN-RELATED FORKHEAD-RELATED TRANSCRIPTION FACTOR FKH-5-RELATED nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of biological process#GO:0050789;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 winged helix/forkhead transcription factor#PC00246 IXOSC|EnsemblGenome=LOC8039664|UniProtKB=A0ACM8EDZ6 A0ACM8EDZ6 LOC8039664 PTHR15712:SF23 ARMADILLO REPEAT CONTAINING PROTEIN ARMADILLO REPEAT CONTAINING 10 axo-dendritic transport#GO:0008088;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;cytoskeleton-dependent intracellular transport#GO:0030705;organelle transport along microtubule#GO:0072384;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;microtubule-based process#GO:0007017;mitochondrion localization#GO:0051646;microtubule-based movement#GO:0007018;establishment of organelle localization#GO:0051656;axonal transport#GO:0098930;organelle localization#GO:0051640;microtubule-based transport#GO:0099111;localization#GO:0051179;cellular localization#GO:0051641 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115322167|UniProtKB=A0ACM8E1R7 A0ACM8E1R7 LOC115322167 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC121047224|UniProtKB=A0ACM8FFN5 A0ACM8FFN5 LOC121047224 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322960|UniProtKB=A0ACM8FDN9 A0ACM8FDN9 LOC115322960 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8043551|UniProtKB=A0ACM8E546 A0ACM8E546 LOC8043551 PTHR11610:SF204 LIPASE PHOSPHOLIPASE A1 1-LIKE PROTEIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788 catabolic process#GO:0009056;lipid catabolic process#GO:0016042;cellular process#GO:0009987;lipid metabolic process#GO:0006629;metabolic process#GO:0008152;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;lipase#PC00143 IXOSC|EnsemblGenome=LOC121836654|UniProtKB=A0ACM8FZ12 A0ACM8FZ12 LOC121836654 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120835925|UniProtKB=A0ACM8EET9 A0ACM8EET9 LOC120835925 PTHR16294:SF8 DYSTROBREVIN BINDING PROTEIN 1 DYSBINDIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120842259|UniProtKB=A0ACM8ETG5 A0ACM8ETG5 LOC120842259 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115310200|UniProtKB=A0ACM8G864 A0ACM8G864 LOC115310200 PTHR46255:SF3 SHORT STATURE HOMEOBOX HOMEOBOX PROTEIN UNC-4 double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulator activity#GO:0140110;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC120838572|UniProtKB=A0ACM8FSH6 A0ACM8FSH6 LOC120838572 PTHR10680:SF39 PEPTIDYL-GLYCINE ALPHA-AMIDATING MONOOXYGENASE PEPTIDYLGLYCINE ALPHA-HYDROXYLATING MONOOXYGENASE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;oxygenase#PC00177;oxidoreductase#PC00176 Vasopressin synthesis#P04395>Amidating Enzyme#P04599 IXOSC|EnsemblGenome=ISCI017479|UniProtKB=B7P877 B7P877 Cbp20 PTHR18847:SF0 20 KD NUCLEAR CAP BINDING PROTEIN NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723 establishment of localization in cell#GO:0051649;cellular process#GO:0009987;mRNA processing#GO:0006397;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA splicing, via spliceosome#GO:0000398;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;nucleic acid biosynthetic process#GO:0141187;RNA catabolic process#GO:0006401;cellular localization#GO:0051641;mRNA export from nucleus#GO:0006406;RNA metabolic process#GO:0016070;negative regulation of macromolecule metabolic process#GO:0010605;macromolecule biosynthetic process#GO:0009059;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;macromolecule localization#GO:0033036;regulation of metabolic process#GO:0019222;nitrogen compound transport#GO:0071705;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;biological regulation#GO:0065007;transport#GO:0006810;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;establishment of localization#GO:0051234;nuclear-transcribed mRNA catabolic process#GO:0000956;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;establishment of RNA localization#GO:0051236;RNA biosynthetic process#GO:0032774;mRNA transport#GO:0051028;nucleobase-containing compound transport#GO:0015931;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;RNA transport#GO:0050658;regulation of cellular process#GO:0050794;RNA localization#GO:0006403;nucleocytoplasmic transport#GO:0006913;RNA splicing, via transesterification reactions#GO:0000375;nuclear transport#GO:0051169;nuclear export#GO:0051168;localization#GO:0051179;nucleic acid transport#GO:0050657;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377 intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8027481|UniProtKB=A0ACM8G8L7 A0ACM8G8L7 LOC8027481 PTHR10217:SF548 VOLTAGE AND LIGAND GATED POTASSIUM CHANNEL GH12235P transporter activity#GO:0005215;voltage-gated monoatomic cation channel activity#GO:0022843;metal ion transmembrane transporter activity#GO:0046873;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;ligand-gated monoatomic cation channel activity#GO:0099094;transmembrane transporter activity#GO:0022857;ligand-gated channel activity#GO:0022834;passive transmembrane transporter activity#GO:0022803;monoatomic cation channel activity#GO:0005261;potassium channel activity#GO:0005267;ligand-gated monoatomic ion channel activity#GO:0015276;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079 cellular process#GO:0009987;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;metal ion transport#GO:0030001;biological regulation#GO:0065007;monoatomic ion transmembrane transport#GO:0034220;potassium ion transport#GO:0006813;transport#GO:0006810;regulation of biological quality#GO:0065008;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;regulation of membrane potential#GO:0042391 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ion channel#PC00133;transporter#PC00227 IXOSC|EnsemblGenome=LOC8039615|UniProtKB=A0ACM8DKE5 A0ACM8DKE5 LOC8039615 PTHR11733:SF167 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI17812P1-RELATED metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604;proteolysis#GO:0006508;metabolic process#GO:0008152;protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 metalloprotease#PC00153;protease#PC00190 Endothelin signaling pathway#P00019>ECE1-3#P00585 IXOSC|EnsemblGenome=LOC115311222|UniProtKB=A0ACM8EJR2 A0ACM8EJR2 LOC115311222 PTHR44085:SF2 SEPIAPTERIN REDUCTASE SEPIAPTERIN REDUCTASE oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 alcohol metabolic process#GO:0006066;metabolic process#GO:0008152;small molecule biosynthetic process#GO:0044283;cellular process#GO:0009987;alcohol biosynthetic process#GO:0046165;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;biosynthetic process#GO:0009058 reductase#PC00198 IXOSC|EnsemblGenome=LOC115321456|UniProtKB=A0ACM8E173 A0ACM8E173 mRpL23 PTHR12059:SF5 RIBOSOMAL PROTEIN L23-RELATED LARGE RIBOSOMAL SUBUNIT PROTEIN UL23M structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 gene expression#GO:0010467;mitochondrial translation#GO:0032543;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;mitochondrial gene expression#GO:0140053;metabolic process#GO:0008152;translation#GO:0006412 membraneless organelle#GO:0043228;mitochondrial large ribosomal subunit#GO:0005762;mitochondrial protein-containing complex#GO:0098798;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organellar ribosome#GO:0000313;mitochondrial ribosome#GO:0005761;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;mitochondrial matrix#GO:0005759;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233;mitochondrion#GO:0005739;ribosome#GO:0005840 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC8027429|UniProtKB=A0ACM8G5A7 A0ACM8G5A7 LOC8027429 PTHR13132:SF29 ALPHA- 1,6 -FUCOSYLTRANSFERASE ALPHA-(1,6)-FUCOSYLTRANSFERASE catalytic activity#GO:0003824;transferase activity#GO:0016740;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757 metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;protein metabolic process#GO:0019538;glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;protein N-linked glycosylation#GO:0006487;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058 glycosyltransferase#PC00111 Notch signaling pathway#P00045>Neurotic#P01115 IXOSC|EnsemblGenome=LOC120837544|UniProtKB=A0ACM8EIC9 A0ACM8EIC9 LOC120837544 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8041454|UniProtKB=A0ACM8G3A9 A0ACM8G3A9 LOC8041454 PTHR14932:SF1 RAS GTPASE-RELATED RAB-LIKE PROTEIN 6 ribonucleotide binding#GO:0032553;purine nucleotide binding#GO:0017076;purine ribonucleoside triphosphate binding#GO:0035639;carbohydrate derivative binding#GO:0097367;nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;guanyl nucleotide binding#GO:0019001;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488;nucleoside phosphate binding#GO:1901265;ion binding#GO:0043167;GTP binding#GO:0005525;guanyl ribonucleotide binding#GO:0032561 nucleus#GO:0005634;cytosol#GO:0005829;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 small GTPase#PC00208 IXOSC|EnsemblGenome=LOC120839771|UniProtKB=A0ACM8ENP7 A0ACM8ENP7 LOC120839771 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839484|UniProtKB=A0ACM8EMF7 A0ACM8EMF7 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN reverse transcriptase#PC00200;viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8036093|UniProtKB=A0ACM8EJS0 A0ACM8EJS0 LOC8036093 PTHR21228:SF74 FAST LEU-RICH DOMAIN-CONTAINING LD32258P binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 cellular process#GO:0009987;RNA processing#GO:0006396;gene expression#GO:0010467;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;regulation of mRNA metabolic process#GO:1903311;regulation of biological process#GO:0050789;regulation of mRNA catabolic process#GO:0061013;regulation of mRNA stability#GO:0043488;nucleic acid biosynthetic process#GO:0141187;regulation of biological quality#GO:0065008;RNA metabolic process#GO:0016070;macromolecule biosynthetic process#GO:0009059;mitochondrial RNA processing#GO:0000963;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biosynthetic process#GO:0009058;biological regulation#GO:0065007;nucleobase-containing compound metabolic process#GO:0006139;regulation of nucleobase-containing compound metabolic process#GO:0019219;post-transcriptional regulation of gene expression#GO:0010608;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;RNA biosynthetic process#GO:0032774;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of RNA stability#GO:0043487;mitochondrial gene expression#GO:0140053;regulation of RNA metabolic process#GO:0051252;mitochondrial RNA metabolic process#GO:0000959 mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;membraneless organelle#GO:0043228;membrane-enclosed lumen#GO:0031974;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC120841920|UniProtKB=A0ACM8FV07 A0ACM8FV07 LOC120841920 PTHR34007:SF1 AEROLYSIN-LIKE PROTEIN-RELATED AEROLYSIN-LIKE-RELATED IXOSC|EnsemblGenome=LOC121833802|UniProtKB=A0ACM8FMS1 A0ACM8FMS1 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120842527|UniProtKB=A0ACM8EU10 A0ACM8EU10 LOC120842527 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115310631|UniProtKB=A0ACM8DPY3 A0ACM8DPY3 LOC115310631 PTHR24406:SF24 TRANSCRIPTIONAL REPRESSOR CTCFL-RELATED ZINC FINGER PROTEIN ZIPIC C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8039065|UniProtKB=A0ACM8DNY3 A0ACM8DNY3 LOC8039065 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;active transmembrane transporter activity#GO:0022804 metal ion transport#GO:0030001;monoatomic ion transport#GO:0006811;localization#GO:0051179;monoatomic cation transport#GO:0006812;establishment of localization#GO:0051234;transport#GO:0006810;sodium ion transport#GO:0006814 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC121047364|UniProtKB=A0ACM8FEQ7 A0ACM8FEQ7 LOC121047364 PTHR11177:SF360 CHITINASE CHITINASE 2-RELATED hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;chitinase activity#GO:0004568;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553 carbohydrate derivative catabolic process#GO:1901136;amino sugar metabolic process#GO:0006040;catabolic process#GO:0009056;cellular process#GO:0009987;carbohydrate derivative metabolic process#GO:1901135;aminoglycan catabolic process#GO:0006026;chitin catabolic process#GO:0006032;amino sugar catabolic process#GO:0046348;macromolecule metabolic process#GO:0043170;chitin metabolic process#GO:0006030;macromolecule catabolic process#GO:0009057;aminoglycan metabolic process#GO:0006022;metabolic process#GO:0008152 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 metabolite interconversion enzyme#PC00262;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8026490|UniProtKB=A0ACM8DUR9 A0ACM8DUR9 LOC8026490 PTHR16277:SF7 CELL DIVISION CYCLE ASSOCIATED PROTEIN 4/SERTA DOMAIN-CONTAINING PROTEIN 2 RE12330P transcription regulator activity#GO:0140110;transcription coregulator activity#GO:0003712;transcription coactivator activity#GO:0003713 intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC121832991|UniProtKB=A0ACM8FXA7 A0ACM8FXA7 LOC121832991 PTHR43969:SF9 GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED GLUTATHIONE S TRANSFERASE D10, ISOFORM A-RELATED transferase#PC00220 IXOSC|EnsemblGenome=LOC8042264|UniProtKB=A0ACM8DVZ4 A0ACM8DVZ4 LOC8042264 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC115323865|UniProtKB=A0ACM8F5Z4 A0ACM8F5Z4 LOC115323865 PTHR23428:SF386 HISTONE H2B HISTONE H2B 1-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC120844183|UniProtKB=A0ACM8EY22 A0ACM8EY22 LOC120844193 PTHR48257:SF2 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115322996|UniProtKB=A0ACM8ET45 A0ACM8ET45 PTHR48623:SF2 SAM DOMAIN-CONTAINING PROTEIN-RELATED SAM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115320001|UniProtKB=A0ACM8E0E8 A0ACM8E0E8 LOC115320001 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8051108|UniProtKB=A0ACM8EAN3 A0ACM8EAN3 LOC8051108 PTHR12287:SF23 EPIDERMAL GROWTH FACTOR RECEPTOR KINASE SUBSTRATE EPS8-RELATED PROTEIN AROUSER, ISOFORM A-RELATED binding#GO:0005488;cytoskeletal protein binding#GO:0008092;actin binding#GO:0003779;protein binding#GO:0005515 regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;cell communication#GO:0007154;Rho protein signal transduction#GO:0007266;intracellular signal transduction#GO:0035556;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;response to stimulus#GO:0050896;regulation of Rho protein signal transduction#GO:0035023;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of cell communication#GO:0010646;regulation of response to stimulus#GO:0048583;regulation of small GTPase mediated signal transduction#GO:0051056;signal transduction#GO:0007165;cellular process#GO:0009987;small GTPase-mediated signal transduction#GO:0007264;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;intracellular signaling cassette#GO:0141124 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120837789|UniProtKB=A0ACM8EJ94 A0ACM8EJ94 LOC120837789 PTHR43826:SF3 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 GLUCOSE-6-PHOSPHATE EXCHANGER SLC37A4 carbohydrate derivative transmembrane transporter activity#GO:1901505;organophosphate ester transmembrane transporter activity#GO:0015605;phosphate transmembrane transporter activity#GO:0005315;active transmembrane transporter activity#GO:0022804;secondary active transmembrane transporter activity#GO:0015291;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;antiporter activity#GO:0015297 transport#GO:0006810;inorganic anion transport#GO:0015698;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;cellular process#GO:0009987;carbohydrate derivative transport#GO:1901264;phosphate ion transport#GO:0006817;organophosphate ester transport#GO:0015748 membrane#GO:0016020;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783;endoplasmic reticulum membrane#GO:0005789;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;intracellular anatomical structure#GO:0005622;organelle membrane#GO:0031090 primary active transporter#PC00068 IXOSC|EnsemblGenome=LOC8032283|UniProtKB=A0ACM8EQ53 A0ACM8EQ53 LOC8032283 PTHR23421:SF165 BETA-GALACTOSIDASE RELATED BETA-GALACTOSIDASE hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;catalytic activity#GO:0003824;hydrolase activity, acting on glycosyl bonds#GO:0016798;hydrolase activity#GO:0016787 metabolic process#GO:0008152;monosaccharide metabolic process#GO:0005996;carbohydrate catabolic process#GO:0016052;hexose metabolic process#GO:0019318;primary metabolic process#GO:0044238;cellular process#GO:0009987;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;carbohydrate metabolic process#GO:0005975;small molecule catabolic process#GO:0044282 galactosidase#PC00104;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120841011|UniProtKB=A0ACM8FVL0 A0ACM8FVL0 LOC120841011 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120838285|UniProtKB=A0ACM8FDE1 A0ACM8FDE1 LOC120838285 PTHR24543:SF339 MULTICOPPER OXIDASE-RELATED LACTADHERIN-LIKE oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8027237|UniProtKB=A0ACM8EC75 A0ACM8EC75 LOC8027237 PTHR11771:SF180 LIPOXYGENASE ARACHIDONATE 5-LIPOXYGENASE oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen#GO:0016702;dioxygenase activity#GO:0051213;oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152;lipid oxidation#GO:0034440;lipid modification#GO:0030258 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120841941|UniProtKB=A0ACM8ETT2 A0ACM8ETT2 LOC120841941 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121046796|UniProtKB=A0ACM8FRJ0 A0ACM8FRJ0 LOC121046796 PTHR33198:SF23 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANS_GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8027571|UniProtKB=A0ACM8FIC2 A0ACM8FIC2 LOC8027571 PTHR47640:SF84 TRNA SELENOCYSTEINE 1-ASSOCIATED PROTEIN 1-RELATED-RELATED CYTOTOXIC GRANULE-ASSOCIATED RNA BINDING PROTEIN TIAR-1-RELATED RNA binding#GO:0003723;binding#GO:0005488;nucleic acid binding#GO:0003676;mRNA binding#GO:0003729 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;cytoplasmic stress granule assembly#GO:0034063;regulation of cellular process#GO:0050794;organelle assembly#GO:0070925;regulation of RNA stability#GO:0043487;regulation of RNA metabolic process#GO:0051252;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;regulation of nucleobase-containing compound metabolic process#GO:0019219;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;macromolecule metabolic process#GO:0043170;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;regulation of catabolic process#GO:0009894;negative regulation of biological process#GO:0048519;regulation of mRNA catabolic process#GO:0061013;cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;negative regulation of gene expression#GO:0010629;regulation of biological process#GO:0050789;negative regulation of metabolic process#GO:0009892;mRNA metabolic process#GO:0016071;regulation of mRNA stability#GO:0043488;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;regulation of biological quality#GO:0065008;organelle organization#GO:0006996;negative regulation of macromolecule biosynthetic process#GO:0010558;mRNA catabolic process#GO:0006402;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cellular component assembly#GO:0022607;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;cellular component organization or biogenesis#GO:0071840;regulation of mRNA metabolic process#GO:1903311 organelle#GO:0043226;ribonucleoprotein granule#GO:0035770;supramolecular complex#GO:0099080;cellular anatomical structure#GO:0110165;cytoplasmic ribonucleoprotein granule#GO:0036464;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;membraneless organelle#GO:0043228;cytoplasmic stress granule#GO:0010494;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115329471|UniProtKB=A0ACM8EKH5 A0ACM8EKH5 LOC115329471 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8027944|UniProtKB=A0ACM8EBC8 A0ACM8EBC8 LOC8027944 PTHR11732:SF506 ALDO/KETO REDUCTASE ALDO-KETO REDUCTASE 1B-RELATED oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491;alcohol dehydrogenase (NADP+) activity#GO:0008106;alcohol dehydrogenase [NAD(P)+] activity#GO:0018455;oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cytosol#GO:0005829 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC8051409|UniProtKB=A0ACM8DLT8 A0ACM8DLT8 LOC8051409 PTHR10218:SF365 GTP-BINDING PROTEIN ALPHA SUBUNIT G PROTEIN ALPHA Q SUBUNIT-RELATED ribonucleoside triphosphate phosphatase activity#GO:0017111;molecular function regulator activity#GO:0098772;catalytic activity#GO:0003824;pyrophosphatase activity#GO:0016462;hydrolase activity, acting on acid anhydrides#GO:0016817;hydrolase activity#GO:0016787;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;GTPase activity#GO:0003924 cell communication#GO:0007154;response to nitrogen compound#GO:1901698;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;response to oxygen-containing compound#GO:1901700;phospholipase C-activating G protein-coupled receptor signaling pathway#GO:0007200;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;regulation of biological process#GO:0050789;cellular response to stimulus#GO:0051716;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;response to chemical#GO:0042221;cellular response to nitrogen compound#GO:1901699;biological regulation#GO:0065007;G protein-coupled dopamine receptor signaling pathway#GO:0007212;signal transduction#GO:0007165;cellular response to oxygen-containing compound#GO:1901701;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;cytoplasmic side of plasma membrane#GO:0009898;membrane protein complex#GO:0098796;plasma membrane protein complex#GO:0098797;side of membrane#GO:0098552;intracellular anatomical structure#GO:0005622;extrinsic component of cytoplasmic side of plasma membrane#GO:0031234;catalytic complex#GO:1902494;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;extrinsic component of plasma membrane#GO:0019897;extrinsic component of membrane#GO:0019898;cytoplasmic side of membrane#GO:0098562 heterotrimeric G-protein#PC00117;G-protein#PC00020 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>G-Protein#P01073;Oxytocin receptor mediated signaling pathway#P04391>G-Protein#P04534;Cortocotropin releasing factor receptor signaling pathway#P04380>G-Protein#P04458;Histamine H1 receptor mediated signaling pathway#P04385>G-Protein#P04488;Endothelin signaling pathway#P00019>Gq#P00586;Thyrotropin-releasing hormone receptor signaling pathway#P04394>G-Protein#P04584;5HT2 type receptor mediated signaling pathway#P04374>G-protein#P04416;Wnt signaling pathway#P00057>Galpha#P01451;PI3 kinase pathway#P00048>Galpha#P01199;Metabotropic glutamate receptor group I pathway#P00041>G-Protein#P01057 IXOSC|EnsemblGenome=LOC115327526|UniProtKB=A0ACM8E760 A0ACM8E760 LOC115327526 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC121838188|UniProtKB=A0ACM8G713 A0ACM8G713 LOC121838188 PTHR47237:SF1 SLL0310 PROTEIN SLL1469 PROTEIN acetyltransferase#PC00038;transferase#PC00220 IXOSC|EnsemblGenome=LOC115318440|UniProtKB=A0ACM8F512 A0ACM8F512 LOC115318440 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8024329|UniProtKB=A0ACM8DPN0 A0ACM8DPN0 LOC8024329 PTHR10907:SF47 REGUCALCIN REGUCALCIN hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;carboxylic ester hydrolase activity#GO:0052689 regulation of biological process#GO:0050789;regulation of calcium-mediated signaling#GO:0050848;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;regulation of cell communication#GO:0010646;regulation of cellular process#GO:0050794;regulation of response to stimulus#GO:0048583;regulation of signaling#GO:0023051;regulation of intracellular signal transduction#GO:1902531 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 esterase#PC00097;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC121833015|UniProtKB=A0ACM8FIU7 A0ACM8FIU7 LOC121833015 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8037932|UniProtKB=A0ACM8DID9 A0ACM8DID9 LOC8037932 PTHR23350:SF0 PEROXISOME ASSEMBLY PROTEIN 10 PEROXISOME BIOGENESIS FACTOR 10 localization#GO:0051179;transmembrane transport#GO:0055085;cellular localization#GO:0051641;protein transport#GO:0015031;peroxisomal transport#GO:0043574;peroxisome organization#GO:0007031;protein localization to organelle#GO:0033365;protein import into peroxisome matrix#GO:0016558;cellular component organization#GO:0016043;establishment of protein localization to organelle#GO:0072594;cellular component organization or biogenesis#GO:0071840;intracellular protein transmembrane transport#GO:0065002;establishment of localization#GO:0051234;intracellular protein localization#GO:0008104;intracellular transport#GO:0046907;protein transmembrane import into intracellular organelle#GO:0044743;protein transmembrane transport#GO:0071806;intracellular protein transport#GO:0006886;transport#GO:0006810;organelle organization#GO:0006996;macromolecule localization#GO:0033036;establishment of protein localization#GO:0045184;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 microbody#GO:0042579;membrane#GO:0016020;peroxisome#GO:0005777;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;peroxisomal membrane#GO:0005778;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;bounding membrane of organelle#GO:0098588;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 chaperone#PC00072 IXOSC|EnsemblGenome=LOC121835633|UniProtKB=A0ACM8FUH6 A0ACM8FUH6 LOC121835633 PTHR24369:SF210 ANTIGEN BSP, PUTATIVE-RELATED CHAOPTIN-RELATED membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC120851092|UniProtKB=A0ACM8FB88 A0ACM8FB88 LOC120851092 PTHR24064:SF713 SOLUTE CARRIER FAMILY 22 MEMBER IP21853P-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 transport#GO:0006810;cellular process#GO:0009987;localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC8042599|UniProtKB=A0ACM8E2G9 A0ACM8E2G9 Tet PTHR23358:SF6 METHYLCYTOSINE DIOXYGENASE TET METHYLCYTOSINE DIOXYGENASE TET oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen#GO:0016705;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;dioxygenase activity#GO:0051213;catalytic activity, acting on DNA#GO:0140097;oxidoreductase activity#GO:0016491;2-oxoglutarate-dependent dioxygenase activity#GO:0016706 regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789;positive regulation of biosynthetic process#GO:0009891;positive regulation of macromolecule biosynthetic process#GO:0010557;positive regulation of metabolic process#GO:0009893;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;positive regulation of macromolecule metabolic process#GO:0010604;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of DNA-templated transcription#GO:0045893;biological regulation#GO:0065007;positive regulation of RNA biosynthetic process#GO:1902680;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC115330741|UniProtKB=A0ACM8FV24 A0ACM8FV24 LOC115330741 PTHR36694:SF11 PASIFLORA 1, ISOFORM A-RELATED LYSOSOMAL-ASSOCIATED TRANSMEMBRANE PROTEIN 4B-LIKE ISOFORM X1 IXOSC|EnsemblGenome=LOC115331284|UniProtKB=A0ACM8F3I3 A0ACM8F3I3 PTHR45810:SF18 HISTONE H3.2 HISTONE H3-LIKE CENTROMERIC PROTEIN A chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC115315715|UniProtKB=A0ACM8DV76 A0ACM8DV76 LOC115315715 PTHR11607:SF72 ALPHA-MANNOSIDASE LYSOSOMAL ALPHA-MANNOSIDASE catalytic activity#GO:0003824;hydrolase activity, hydrolyzing O-glycosyl compounds#GO:0004553;hydrolase activity#GO:0016787;hydrolase activity, acting on glycosyl bonds#GO:0016798 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;lytic vacuole#GO:0000323;lysosome#GO:0005764;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;vacuole#GO:0005773;cellular anatomical structure#GO:0110165;organelle#GO:0043226 hydrolase#PC00121;glycosidase#PC00110 IXOSC|EnsemblGenome=LOC8051845|UniProtKB=A0ACM8DSW6 A0ACM8DSW6 LOC8051845 PTHR11092:SF0 SUGAR NUCLEOTIDE EPIMERASE RELATED EPIMERASE FAMILY PROTEIN SDR39U1 epimerase/racemase#PC00096 IXOSC|EnsemblGenome=LOC8025183|UniProtKB=A0ACM8F510 A0ACM8F510 LOC8025183 PTHR35385:SF2 PROTEIN B, PUTATIVE-RELATED-RELATED SWIM-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121835675|UniProtKB=A0ACM8FUP6 A0ACM8FUP6 LOC121835675 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC121048154|UniProtKB=A0ACM8FHK4 A0ACM8FHK4 LOC121048154 PTHR33053:SF28 PROTEIN, PUTATIVE-RELATED TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8040550|UniProtKB=A0ACM8DKL8 A0ACM8DKL8 LOC8040550 PTHR23199:SF18 NEUROTROPHIN 1-RELATED PROTEIN SPAETZLE-RELATED signaling receptor binding#GO:0005102;binding#GO:0005488;molecular function activator activity#GO:0140677;protein binding#GO:0005515;growth factor activity#GO:0008083;signaling receptor regulator activity#GO:0030545;receptor ligand activity#GO:0048018;signaling receptor activator activity#GO:0030546;molecular function regulator activity#GO:0098772 response to external biotic stimulus#GO:0043207;biological process involved in interspecies interaction between organisms#GO:0044419;response to stimulus#GO:0050896;central nervous system development#GO:0007417;anatomical structure morphogenesis#GO:0009653;system development#GO:0048731;anatomical structure development#GO:0048856;animal gross anatomical part developmental process#GO:0160108;immune system process#GO:0002376;nervous system development#GO:0007399;response to other organism#GO:0051707;defense response to other organism#GO:0098542;multicellular organismal process#GO:0032501;defense response to symbiont#GO:0140546;immune response#GO:0006955;response to stress#GO:0006950;response to biotic stimulus#GO:0009607;defense response#GO:0006952;anatomical structure formation involved in morphogenesis#GO:0048646;response to external stimulus#GO:0009605;innate immune response#GO:0045087;multicellular organism development#GO:0007275;developmental process#GO:0032502 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 Toll pathway-drosophila#P06217>SPZ#P06349;Toll pathway-drosophila#P06217>SPZ full length#P06347 IXOSC|EnsemblGenome=LOC115310938|UniProtKB=A0ACM8DQ74 A0ACM8DQ74 LOC115310938 PTHR20908:SF1 LD15586P LD15586P IXOSC|EnsemblGenome=LOC120846863|UniProtKB=A0ACM8F499 A0ACM8F499 LOC120846863 PTHR23184:SF9 TETRATRICOPEPTIDE REPEAT PROTEIN 14 TETRATRICOPEPTIDE REPEAT PROTEIN 14 IXOSC|EnsemblGenome=LOC8036626|UniProtKB=A0ACM8DHJ5 A0ACM8DHJ5 LOC8036626 PTHR11567:SF213 ACID PHOSPHATASE-RELATED 2-PHOSPHOXYLOSE PHOSPHATASE 1 catalytic activity#GO:0003824;phosphatase activity#GO:0016791;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787;phosphoric ester hydrolase activity#GO:0042578 macromolecule metabolic process#GO:0043170;carbohydrate derivative biosynthetic process#GO:1901137;proteoglycan metabolic process#GO:0006029;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;proteoglycan biosynthetic process#GO:0030166;biosynthetic process#GO:0009058;chondroitin sulfate proteoglycan biosynthetic process#GO:0050650;glycoprotein biosynthetic process#GO:0009101;carbohydrate derivative metabolic process#GO:1901135;protein O-linked glycosylation#GO:0006493;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;chondroitin sulfate proteoglycan metabolic process#GO:0050654;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;Golgi apparatus#GO:0005794;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 phosphatase#PC00181 IXOSC|EnsemblGenome=LOC115314249|UniProtKB=A0ACM8EQ10 A0ACM8EQ10 LOC115314249 PTHR12243:SF69 MADF DOMAIN TRANSCRIPTION FACTOR GH22016P-RELATED regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;nucleus#GO:0005634;transcription regulator complex#GO:0005667;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 DNA-binding transcription factor#PC00218 IXOSC|EnsemblGenome=LOC115327540|UniProtKB=A0ACM8FCS5 A0ACM8FCS5 LOC115327540 PTHR47020:SF1 HILLARIN HILLARIN cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121836787|UniProtKB=A0ACM8G037 A0ACM8G037 LOC121836787 PTHR48543:SF1 FAMILY NOT NAMED REVERSE TRANSCRIPTASE ZINC-BINDING DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051682|UniProtKB=A0ACM8E5U8 A0ACM8E5U8 LOC8051682 PTHR31193:SF1 TRANSMEMBRANE PROTEIN C9ORF91 TRANSMEMBRANE PROTEIN 268 IXOSC|EnsemblGenome=LOC8037007|UniProtKB=A0ACM8E0H0 A0ACM8E0H0 RhoGAP19D PTHR23175:SF23 PDZ DOMAIN-CONTAINING PROTEIN RHO GTPASE-ACTIVATING 92B-LIKE PROTEIN molecular function regulator activity#GO:0098772;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;nucleoside-triphosphatase regulator activity#GO:0060589;GTPase regulator activity#GO:0030695;GTPase activator activity#GO:0005096;enzyme activator activity#GO:0008047 IXOSC|EnsemblGenome=LOC8031633|UniProtKB=A0ACM8E2A5 A0ACM8E2A5 LOC8031633 PTHR24373:SF386 SLIT RELATED LEUCINE-RICH REPEAT NEURONAL PROTEIN LEUCINE-RICH REPEAT NEURONAL PROTEIN signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8041598|UniProtKB=A0ACM8DKQ8 A0ACM8DKQ8 tex PTHR22839:SF0 THO COMPLEX SUBUNIT 3 THO3 THO COMPLEX SUBUNIT 3 gene expression#GO:0010467;biosynthetic process#GO:0009058;macromolecule localization#GO:0033036;nitrogen compound transport#GO:0071705;establishment of localization in cell#GO:0051649;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;metabolic process#GO:0008152;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;transport#GO:0006810;nucleobase-containing compound transport#GO:0015931;RNA localization#GO:0006403;RNA transport#GO:0050658;establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;localization#GO:0051179;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;mRNA export from nucleus#GO:0006406;nuclear transport#GO:0051169;nuclear export#GO:0051168;nucleocytoplasmic transport#GO:0006913 nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;THO complex#GO:0000347;intracellular organelle#GO:0043229;transcription export complex#GO:0000346;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120836859|UniProtKB=A0ACM8FYL5 A0ACM8FYL5 LOC120836859 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8041987|UniProtKB=A0ACM8DKU3 A0ACM8DKU3 CCT7 PTHR11353:SF22 CHAPERONIN T-COMPLEX PROTEIN 1 SUBUNIT ETA metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;gene expression#GO:0010467;protein maturation#GO:0051604;biosynthetic process#GO:0009058;protein folding#GO:0006457 chaperonin-containing T-complex#GO:0005832;intracellular protein-containing complex#GO:0140535;intracellular anatomical structure#GO:0005622;protein folding chaperone complex#GO:0101031;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;cytosol#GO:0005829 chaperonin#PC00073 IXOSC|EnsemblGenome=LOC8033368|UniProtKB=A0ACM8EGJ1 A0ACM8EGJ1 LOC8033368 PTHR14469:SF0 SARCOMA ANTIGEN NY-SAR-23 FAMILY WITH SEQUENCE SIMILARITY 113 IXOSC|EnsemblGenome=LOC121045777|UniProtKB=A0ACM8FV65 A0ACM8FV65 LOC121045777 PTHR18952:SF295 CARBONIC ANHYDRASE CARBONIC ANHYDRASE catalytic activity#GO:0003824;carbon-oxygen lyase activity#GO:0016835;lyase activity#GO:0016829;hydro-lyase activity#GO:0016836 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 metabolite interconversion enzyme#PC00262;dehydratase#PC00091 IXOSC|EnsemblGenome=LOC115312627|UniProtKB=A0ACM8G4K6 A0ACM8G4K6 LOC115312627 PTHR31569:SF7 SWIM-TYPE DOMAIN-CONTAINING PROTEIN ZSWIM1_3 RNASEH-LIKE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8051921|UniProtKB=A0ACM8DR50 A0ACM8DR50 LOC8051921 PTHR31596:SF1 T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL T-CELL ACTIVATION INHIBITOR, MITOCHONDRIAL intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrion#GO:0005739;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115318164|UniProtKB=A0ACM8EV59 A0ACM8EV59 LOC115318164 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 metalloprotease#PC00153;protease#PC00190 IXOSC|EnsemblGenome=LOC8024477|UniProtKB=A0ACM8DIC9 A0ACM8DIC9 mago PTHR12638:SF0 PROTEIN MAGO NASHI HOMOLOG MAGO HOMOLOG, EXON JUNCTION COMPLEX SUBUNIT-RELATED primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;nuclear-transcribed mRNA catabolic process#GO:0000956;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;nucleic acid catabolic process#GO:0141188;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;nucleobase-containing compound catabolic process#GO:0034655;nuclear mRNA surveillance#GO:0071028;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;biosynthetic process#GO:0009058;RNA catabolic process#GO:0006401;nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;negative regulation of biological process#GO:0048519;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;RNA splicing#GO:0008380;nuclear-transcribed mRNA catabolic process, nonsense-mediated decay#GO:0000184;macromolecule catabolic process#GO:0009057;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;RNA processing#GO:0006396;gene expression#GO:0010467 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;exon-exon junction complex#GO:0035145;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;nucleus#GO:0005634;spliceosomal complex#GO:0005681 IXOSC|EnsemblGenome=LOC120836261|UniProtKB=A0ACM8FUL7 A0ACM8FUL7 LOC120836261 PTHR24252:SF36 ACROSIN-RELATED CHYMOTRYPSIN-LIKE PROTEIN catalytic activity#GO:0003824;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;serine-type peptidase activity#GO:0008236;serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787 cellular process#GO:0009987;primary metabolic process#GO:0044238;catabolic process#GO:0009056;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC8036848|UniProtKB=A0ACM8DK10 A0ACM8DK10 PTHR23102:SF24 CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4-RELATED CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 4 nucleic acid biosynthetic process#GO:0141187;RNA metabolic process#GO:0016070;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;nucleobase-containing compound biosynthetic process#GO:0034654;mRNA 3'-end processing#GO:0031124;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;RNA 3'-end processing#GO:0031123;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467 nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;protein-containing complex#GO:0032991;mRNA cleavage factor complex#GO:0005849;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;mRNA cleavage and polyadenylation specificity factor complex#GO:0005847;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513 RNA splicing factor#PC00148 IXOSC|EnsemblGenome=LOC120840629|UniProtKB=A0ACM8EQL2 A0ACM8EQL2 LOC120840629 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8034007|UniProtKB=A0ACM8FA47 A0ACM8FA47 LOC8034007 PTHR43757:SF11 AMINOMETHYLTRANSFERASE SARCOSINE DEHYDROGENASE, MITOCHONDRIAL catalytic activity#GO:0003824;transferase activity#GO:0016740;transferase activity, transferring one-carbon groups#GO:0016741 amino acid metabolic process#GO:0006520;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;proteinogenic amino acid metabolic process#GO:0170039;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;primary metabolic process#GO:0044238;carboxylic acid metabolic process#GO:0019752;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 methyltransferase#PC00155;transferase#PC00220 IXOSC|EnsemblGenome=LOC115308525|UniProtKB=A0ACM8FQ81 A0ACM8FQ81 LOC115308525 PTHR31025:SF34 SI:CH211-196P9.1-RELATED IP13529P IXOSC|EnsemblGenome=LOC121046145|UniProtKB=A0ACM8FC30 A0ACM8FC30 LOC121046145 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115315981|UniProtKB=A0ACM8DVF7 A0ACM8DVF7 LOC115315981 PTHR24064:SF688 SOLUTE CARRIER FAMILY 22 MEMBER GH28654P transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215 localization#GO:0051179;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;transport#GO:0006810;cellular process#GO:0009987 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC115318697|UniProtKB=A0ACM8ESM8 A0ACM8ESM8 LOC115318697 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 cellular process#GO:0009987;transport#GO:0006810;localization#GO:0051179;transmembrane transport#GO:0055085;establishment of localization#GO:0051234 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC8026816|UniProtKB=A0ACM8G261 A0ACM8G261 LOC8026816 PTHR45418:SF8 CANCER/TESTIS ANTIGEN 55 RNA HELICASE MOV10L1 IXOSC|EnsemblGenome=LOC121836313|UniProtKB=A0ACM8FY92 A0ACM8FY92 LOC121836313 PTHR13234:SF8 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GILT-LIKE PROTEIN F37H8.5 catalytic activity#GO:0003824;oxidoreductase activity#GO:0016491 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8033234|UniProtKB=A0ACM8FQZ6 A0ACM8FQZ6 gish PTHR11909:SF520 CASEIN KINASE-RELATED NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE catalytic activity, acting on a protein#GO:0140096;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein kinase activity#GO:0004672;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein serine/threonine kinase activity#GO:0004674 regulation of signaling#GO:0023051;positive regulation of signaling#GO:0023056;cell communication#GO:0007154;positive regulation of signal transduction#GO:0009967;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;positive regulation of cell communication#GO:0010647;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;regulation of Wnt signaling pathway#GO:0030111;regulation of cell communication#GO:0010646;signaling#GO:0023052;regulation of response to stimulus#GO:0048583;positive regulation of canonical Wnt signaling pathway#GO:0090263;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;signal transduction#GO:0007165;positive regulation of cellular process#GO:0048522;positive regulation of response to stimulus#GO:0048584;positive regulation of Wnt signaling pathway#GO:0030177;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966 membrane#GO:0016020;cell periphery#GO:0071944;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 non-receptor serine/threonine protein kinase#PC00167 Parkinson disease#P00049>Casein kinase I#P01242;Wnt signaling pathway#P00057>Casein Kinase 1#P01460 IXOSC|EnsemblGenome=LOC8039100|UniProtKB=A0ACM8DKA3 A0ACM8DKA3 Trax PTHR10741:SF5 TRANSLIN AND TRANSLIN ASSOCIATED PROTEIN X TRANSLIN-ASSOCIATED PROTEIN X binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723;nuclease activity#GO:0004518;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;endonuclease activity#GO:0004519;RNA nuclease activity#GO:0004540;catalytic activity, acting on RNA#GO:0140098;RNA endonuclease activity#GO:0004521 organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8031832|UniProtKB=A0ACM8DQF1 A0ACM8DQF1 LOC8031832 PTHR12537:SF195 RNA BINDING PROTEIN PUMILIO-RELATED MATERNAL PROTEIN PUMILIO mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488;RNA binding#GO:0003723;mRNA 3'-UTR binding#GO:0003730 regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222 nucleus#GO:0005634;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120847419|UniProtKB=A0ACM8F362 A0ACM8F362 LOC120847419 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic cation transmembrane transporter activity#GO:0008324;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;monoamine transmembrane transporter activity#GO:0008504;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8043453|UniProtKB=A0ACM8E665 A0ACM8E665 LOC8043453 PTHR43243:SF105 INNER MEMBRANE TRANSPORTER YGJI-RELATED CATIONIC AMINO ACID TRANSPORTER C-TERMINAL DOMAIN-CONTAINING PROTEIN amino acid transmembrane transporter activity#GO:0015171;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 amino acid transport#GO:0006865;transport#GO:0006810;localization#GO:0051179;establishment of localization#GO:0051234 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;amino acid transporter#PC00046 IXOSC|EnsemblGenome=LOC8039193|UniProtKB=A0ACM8DNW1 A0ACM8DNW1 LOC8039193 PTHR33236:SF5 INTRAFLAGELLAR TRANSPORT PROTEIN 122 FAMILY PROTEIN-RELATED CUB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120849612|UniProtKB=A0ACM8G1X5 A0ACM8G1X5 LOC120849612 PTHR11938:SF152 FAD NADPH DEHYDROGENASE/OXIDOREDUCTASE GLUTAMATE SYNTHASE [NADH] oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 intracellular chemical homeostasis#GO:0055082;cellular homeostasis#GO:0019725;proteinogenic amino acid biosynthetic process#GO:0170038;small molecule biosynthetic process#GO:0044283;chemical homeostasis#GO:0048878;metabolic process#GO:0008152;amino acid biosynthetic process#GO:0008652;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;cellular process#GO:0009987;response to nutrient levels#GO:0031667;oxoacid metabolic process#GO:0043436;homeostatic process#GO:0042592;response to stimulus#GO:0050896;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238 oxidoreductase#PC00176;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034036|UniProtKB=A0ACM8DIR5 A0ACM8DIR5 Mesh1 PTHR46246:SF1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE MESH1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;hydrolase activity, acting on ester bonds#GO:0016788;catalytic activity#GO:0003824 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115309590|UniProtKB=A0ACM8FCP8 A0ACM8FCP8 LOC115309590 PTHR33198:SF25 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED APPLE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120838736|UniProtKB=A0ACM8EL64 A0ACM8EL64 l(2)gd1 PTHR13076:SF9 COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE COILED-COIL AND C2 DOMAIN-CONTAINING PROTEIN 1-LIKE double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;binding#GO:0005488;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 nucleus#GO:0005634;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC120845317|UniProtKB=A0ACM8F0C0 A0ACM8F0C0 LOC120845317 PTHR47055:SF4 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT DERIVED 2 sequence-specific DNA binding#GO:0043565;DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 IXOSC|EnsemblGenome=LOC115324312|UniProtKB=A0ACM8G0V6 A0ACM8G0V6 LOC115324312 PTHR23506:SF46 GH10249P MFS-TYPE TRANSPORTER SLC18B1-LIKE PROTEIN monoatomic ion transmembrane transporter activity#GO:0015075;active transmembrane transporter activity#GO:0022804;proton transmembrane transporter activity#GO:0015078;antiporter activity#GO:0015297;secondary active transmembrane transporter activity#GO:0015291;monoamine transmembrane transporter activity#GO:0008504;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;monoatomic cation transmembrane transporter activity#GO:0008324 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8052654|UniProtKB=A0ACM8E8E2 A0ACM8E8E2 Cdc27 PTHR12558:SF13 CELL DIVISION CYCLE 16,23,27 CELL DIVISION CYCLE PROTEIN 27 HOMOLOG protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767 macromolecule metabolic process#GO:0043170;mitotic cell cycle process#GO:1903047;ubiquitin-dependent protein catabolic process#GO:0006511;regulation of chromosome organization#GO:0033044;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;biological regulation#GO:0065007;post-translational protein modification#GO:0043687;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;mitotic cell cycle phase transition#GO:0044772;mitotic cell cycle#GO:0000278;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;cell cycle phase transition#GO:0044770;cell cycle#GO:0007049;protein modification process#GO:0036211;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cell division#GO:0051301;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;regulation of chromosome segregation#GO:0051983;metaphase/anaphase transition of cell cycle#GO:0044784;protein ubiquitination#GO:0016567;regulation of cell cycle process#GO:0010564;proteasomal protein catabolic process#GO:0010498;cellular process#GO:0009987;protein modification by small protein conjugation or removal#GO:0070647;metaphase/anaphase transition of mitotic cell cycle#GO:0007091;anaphase-promoting complex-dependent catabolic process#GO:0031145;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;regulation of sister chromatid segregation#GO:0033045;regulation of biological process#GO:0050789;protein modification by small protein conjugation#GO:0032446;cell cycle process#GO:0022402;regulation of organelle organization#GO:0033043 cellular anatomical structure#GO:0110165;organelle#GO:0043226;nuclear ubiquitin ligase complex#GO:0000152;intracellular membrane-bounded organelle#GO:0043231;cullin-RING ubiquitin ligase complex#GO:0031461;ubiquitin ligase complex#GO:0000151;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;catalytic complex#GO:1902494;intracellular organelle#GO:0043229;anaphase-promoting complex#GO:0005680;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular protein-containing complex#GO:0140535;transferase complex#GO:1990234 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8038078|UniProtKB=A0ACM8DWF1 A0ACM8DWF1 LOC8038078 PTHR45664:SF22 PROTEIN ZERKNUELLT 1-RELATED HOMEOTIC PROTEIN BICOID-RELATED cis-regulatory region sequence-specific DNA binding#GO:0000987;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355 cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;nucleus#GO:0005634;intracellular organelle#GO:0043229 homeodomain transcription factor#PC00119 IXOSC|EnsemblGenome=LOC115314993|UniProtKB=A0ACM8DUC9 A0ACM8DUC9 Sf3a1 PTHR15316:SF1 SPLICEOSOME ASSOCIATED PROTEIN 114/SWAP SPLICING FACTOR-RELATED SPLICING FACTOR 3A SUBUNIT 1 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;mRNA cis splicing, via spliceosome#GO:0045292;mRNA metabolic process#GO:0016071;RNA biosynthetic process#GO:0032774;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;RNA metabolic process#GO:0016070;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;RNA processing#GO:0006396;gene expression#GO:0010467;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170 catalytic complex#GO:1902494;intracellular organelle#GO:0043229;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;spliceosomal snRNP complex#GO:0097525;spliceosomal complex#GO:0005681;U2-type prespliceosome#GO:0071004;intracellular membrane-bounded organelle#GO:0043231;U2-type spliceosomal complex#GO:0005684;organelle#GO:0043226;cellular anatomical structure#GO:0110165;U2 snRNP#GO:0005686;nuclear protein-containing complex#GO:0140513;Sm-like protein family complex#GO:0120114;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;small nuclear ribonucleoprotein complex#GO:0030532;protein-containing complex#GO:0032991 RNA splicing factor#PC00148;RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8036835|UniProtKB=A0ACM8DK15 A0ACM8DK15 PTHR13505:SF7 TRANSMEMBRANE PROTEIN 208 TRANSMEMBRANE PROTEIN 208 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;endoplasmic reticulum#GO:0005783;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum membrane#GO:0005789;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8032112|UniProtKB=A0ACM8EUW0 A0ACM8EUW0 LOC8032112 PTHR24300:SF375 CYTOCHROME P450 508A4-RELATED CYTOCHROME P450 554A1-RELATED response to stimulus#GO:0050896;response to chemical#GO:0042221;xenobiotic metabolic process#GO:0006805;cellular response to xenobiotic stimulus#GO:0071466;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;metabolic process#GO:0008152;response to xenobiotic stimulus#GO:0009410;cellular response to chemical stimulus#GO:0070887 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8035087|UniProtKB=A0ACM8E9P5 A0ACM8E9P5 LOC8035087 PTHR43511:SF4 FAMILY NOT NAMED UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE IXOSC|EnsemblGenome=LOC120843703|UniProtKB=A0ACM8EXS8 A0ACM8EXS8 LOC120843703 PTHR48556:SF1 FAMILY NOT NAMED SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC120843274|UniProtKB=A0ACM8EVR7 A0ACM8EVR7 LOC120843274 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC120849844|UniProtKB=A0ACM8FIU0 A0ACM8FIU0 LOC120849844 PTHR31912:SF37 IP13529P C2H2-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115315565|UniProtKB=A0ACM8EY37 A0ACM8EY37 LOC115315565 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC115317009|UniProtKB=A0ACM8DX18 A0ACM8DX18 LOC115326151 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC121832945|UniProtKB=A0ACM8G5M2 A0ACM8G5M2 LOC121832945 PTHR19818:SF173 ZINC FINGER PROTEIN ZIC AND GLI SUBFAMILY NOT NAMED RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837 regulation of transcription by RNA polymerase II#GO:0006357;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC8028605|UniProtKB=A0ACM8E706 A0ACM8E706 PTHR22702:SF1 PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN PROTEASE-ASSOCIATED DOMAIN-CONTAINING PROTEIN 1 IXOSC|EnsemblGenome=LOC8032942|UniProtKB=A0ACM8ES17 A0ACM8ES17 Vps53 PTHR12820:SF0 VACUOLAR SORTING PROTEIN 53 VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 53 HOMOLOG retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;intracellular transport#GO:0046907;transport#GO:0006810;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197 vesicle#GO:0031982;intracellular vesicle#GO:0097708;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;vesicle tethering complex#GO:0099023 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC115326793|UniProtKB=A0ACM8E6D2 A0ACM8E6D2 PTHR43715:SF1 GDP-MANNOSE 4,6-DEHYDRATASE GDP-MANNOSE 4,6 DEHYDRATASE dehydratase#PC00091;lyase#PC00144 Mannose metabolism#P02752>GDP-Mannose 4,6-dehydratase#P03015 IXOSC|EnsemblGenome=LOC8044060|UniProtKB=A0ACM8G684 A0ACM8G684 LOC8044060 PTHR24243:SF241 G-PROTEIN COUPLED RECEPTOR NEUROPEPTIDES CAPA RECEPTOR G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;neuropeptide receptor activity#GO:0008188;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;neuropeptide signaling pathway#GO:0007218;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115324500|UniProtKB=A0ACM8E598 A0ACM8E598 LOC115324500 PTHR31394:SF1 TRANSMEMBRANE PROTEIN 199 VACUOLAR ATPASE ASSEMBLY PROTEIN VMA12 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120843720|UniProtKB=A0ACM8G2Q2 A0ACM8G2Q2 LOC120843720 PTHR19229:SF275 ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2 active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626 localization#GO:0051179;lipid transport#GO:0006869;establishment of localization#GO:0051234;macromolecule localization#GO:0033036;lipid localization#GO:0010876;transport#GO:0006810 intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC115319637|UniProtKB=A0ACM8E053 A0ACM8E053 PTHR18866:SF130 CARBOXYLASE:PYRUVATE/ACETYL-COA/PROPIONYL-COA CARBOXYLASE PROPIONYL-COA CARBOXYLASE ALPHA CHAIN, MITOCHONDRIAL catalytic activity#GO:0003824;ligase activity#GO:0016874 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;mitochondrion#GO:0005739 ligase#PC00142;metabolite interconversion enzyme#PC00262 Methylmalonyl pathway#P02755>Propionyl-CoA carboxylase#P03033 IXOSC|EnsemblGenome=LOC120851080|UniProtKB=A0ACM8EEF0 A0ACM8EEF0 LOC120851080 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121835750|UniProtKB=A0ACM8FWS5 A0ACM8FWS5 LOC121835750 PTHR22930:SF299 FAMILY NOT NAMED NUCLEASE HARBI1-RELATED IXOSC|EnsemblGenome=LOC120849693|UniProtKB=A0ACM8F952 A0ACM8F952 LOC120849693 PTHR36943:SF2 CCHC-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120850479|UniProtKB=A0ACM8FAX3 A0ACM8FAX3 LOC120850479 PTHR23300:SF0 METHANETHIOL OXIDASE METHANETHIOL OXIDASE defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8032439|UniProtKB=A0ACM8G098 A0ACM8G098 LOC8032439 PTHR47735:SF9 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4 POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4-LIKE ISOFORM X1 monoatomic cation transmembrane transporter activity#GO:0008324;voltage-gated channel activity#GO:0022832;gated channel activity#GO:0022836;voltage-gated potassium channel activity#GO:0005249;voltage-gated monoatomic ion channel activity#GO:0005244;metal ion transmembrane transporter activity#GO:0046873;voltage-gated monoatomic cation channel activity#GO:0022843;monoatomic ion channel activity#GO:0005216;monoatomic ion transmembrane transporter activity#GO:0015075;transporter activity#GO:0005215;channel activity#GO:0015267;potassium ion transmembrane transporter activity#GO:0015079;potassium channel activity#GO:0005267;monoatomic cation channel activity#GO:0005261;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803 transport#GO:0006810;monoatomic ion transport#GO:0006811;transmembrane transport#GO:0055085;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;cellular process#GO:0009987;monoatomic ion transmembrane transport#GO:0034220;potassium ion transmembrane transport#GO:0071805;monoatomic cation transmembrane transport#GO:0098655;metal ion transport#GO:0030001;potassium ion transport#GO:0006813 cation channel complex#GO:0034703;voltage-gated potassium channel complex#GO:0008076;transmembrane transporter complex#GO:1902495;transporter complex#GO:1990351;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;monoatomic ion channel complex#GO:0034702;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 voltage-gated ion channel#PC00241;transporter#PC00227 IXOSC|EnsemblGenome=LOC115318167|UniProtKB=A0ACM8DY80 A0ACM8DY80 LOC115318167 PTHR13100:SF10 CELL GROWTH-REGULATING NUCLEOLAR PROTEIN LYAR CELL GROWTH-REGULATING NUCLEOLAR PROTEIN nucleic acid binding#GO:0003676;binding#GO:0005488;DNA binding#GO:0003677 negative regulation of nucleobase-containing compound metabolic process#GO:0045934;negative regulation of DNA-templated transcription#GO:0045892;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;ribonucleoprotein complex biogenesis#GO:0022613;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;cellular component organization or biogenesis#GO:0071840;negative regulation of RNA biosynthetic process#GO:1902679;negative regulation of RNA metabolic process#GO:0051253;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;rRNA processing#GO:0006364;regulation of RNA metabolic process#GO:0051252;negative regulation of transcription by RNA polymerase II#GO:0000122;regulation of DNA-templated transcription#GO:0006355;RNA biosynthetic process#GO:0032774;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;macromolecule metabolic process#GO:0043170;negative regulation of cellular process#GO:0048523;rRNA metabolic process#GO:0016072;nucleobase-containing compound metabolic process#GO:0006139;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;biosynthetic process#GO:0009058;regulation of RNA biosynthetic process#GO:2001141;regulation of nucleobase-containing compound metabolic process#GO:0019219;macromolecule biosynthetic process#GO:0009059;negative regulation of macromolecule metabolic process#GO:0010605;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 RNA processing factor#PC00147 IXOSC|EnsemblGenome=LOC8034218|UniProtKB=A0ACM8DJ44 A0ACM8DJ44 Ubc6 PTHR24067:SF392 UBIQUITIN-CONJUGATING ENZYME E2 UBIQUITIN-CONJUGATING ENZYME E2-17 KDA ubiquitin-like protein conjugating enzyme activity#GO:0061650;ubiquitin-protein transferase activity#GO:0004842;ubiquitin-like protein transferase activity#GO:0019787;acyltransferase activity#GO:0016746;aminoacyltransferase activity#GO:0016755;catalytic activity, acting on a protein#GO:0140096;ubiquitin conjugating enzyme activity#GO:0061631;transferase activity#GO:0016740;catalytic activity#GO:0003824 protein metabolic process#GO:0019538;macromolecule modification#GO:0043412;modification-dependent macromolecule catabolic process#GO:0043632;protein catabolic process#GO:0030163;cellular response to stress#GO:0033554;protein modification by small protein conjugation or removal#GO:0070647;response to stimulus#GO:0050896;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;protein polyubiquitination#GO:0000209;protein modification by small protein conjugation#GO:0032446;modification-dependent protein catabolic process#GO:0019941;nucleic acid metabolic process#GO:0090304;protein modification process#GO:0036211;primary metabolic process#GO:0044238;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;DNA metabolic process#GO:0006259;macromolecule catabolic process#GO:0009057;DNA repair#GO:0006281;metabolic process#GO:0008152;proteasomal protein catabolic process#GO:0010498;post-translational protein modification#GO:0043687;protein ubiquitination#GO:0016567;nucleobase-containing compound metabolic process#GO:0006139;cellular process#GO:0009987;response to stress#GO:0006950 chromatin#GO:0000785;chromosome#GO:0005694;cytoplasm#GO:0005737;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;transferase complex#GO:1990234;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membraneless organelle#GO:0043228;ubiquitin ligase complex#GO:0000151 protein modifying enzyme#PC00260;ubiquitin-protein ligase#PC00234 Ubiquitin proteasome pathway#P00060>E2#P01491 IXOSC|EnsemblGenome=LOC115324735|UniProtKB=A0ACM8E461 A0ACM8E461 LOC115324735 PTHR10574:SF446 NETRIN/LAMININ-RELATED WING BLISTER, ISOFORM B extracellular matrix structural constituent#GO:0005201;structural molecule activity#GO:0005198 animal gross anatomical part developmental process#GO:0160108;generation of neurons#GO:0048699;anatomical structure development#GO:0048856;system development#GO:0048731;axonogenesis#GO:0007409;neuron development#GO:0048666;cellular component organization#GO:0016043;anatomical structure morphogenesis#GO:0009653;cell projection organization#GO:0030030;cell differentiation#GO:0030154;cell morphogenesis#GO:0000902;cell development#GO:0048468;developmental process#GO:0032502;neuron differentiation#GO:0030182;neuron projection morphogenesis#GO:0048812;plasma membrane bounded cell projection morphogenesis#GO:0120039;multicellular organism development#GO:0007275;cellular component organization or biogenesis#GO:0071840;cellular developmental process#GO:0048869;cell projection morphogenesis#GO:0048858;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;neuron projection development#GO:0031175;axon development#GO:0061564;axon guidance#GO:0007411;cellular process#GO:0009987;tissue development#GO:0009888;multicellular organismal process#GO:0032501;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;basement membrane#GO:0005604;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 extracellular matrix protein#PC00102 Integrin signalling pathway#P00034>Laminin#P00947 IXOSC|EnsemblGenome=LOC8043772|UniProtKB=A0ACM8E244 A0ACM8E244 LOC8043772 PTHR23103:SF18 ALZHEIMER'S DISEASE BETA-AMYLOID RELATED AMYLOID-BETA-LIKE PROTEIN cellular process#GO:0009987;neuron projection development#GO:0031175;axon development#GO:0061564;nervous system development#GO:0007399;plasma membrane bounded cell projection organization#GO:0120036;cell morphogenesis involved in neuron differentiation#GO:0048667;multicellular organismal process#GO:0032501;neuron differentiation#GO:0030182;developmental process#GO:0032502;plasma membrane bounded cell projection morphogenesis#GO:0120039;neuron projection morphogenesis#GO:0048812;cell projection morphogenesis#GO:0048858;neurogenesis#GO:0022008;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;anatomical structure morphogenesis#GO:0009653;cellular component organization#GO:0016043;cell development#GO:0048468;cell differentiation#GO:0030154;cell projection organization#GO:0030030;central nervous system development#GO:0007417;cell morphogenesis#GO:0000902;generation of neurons#GO:0048699;animal gross anatomical part developmental process#GO:0160108;system development#GO:0048731;neuron development#GO:0048666;axonogenesis#GO:0007409;anatomical structure development#GO:0048856 cell body#GO:0044297;neuron projection#GO:0043005;cellular anatomical structure#GO:0110165;neuronal cell body#GO:0043025;cell projection#GO:0042995;somatodendritic compartment#GO:0036477;plasma membrane bounded cell projection#GO:0120025 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115320098|UniProtKB=A0ACM8FTQ2 A0ACM8FTQ2 LOC115320098 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of biological process#GO:0050789;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of DNA-templated transcription#GO:0006355;regulation of biosynthetic process#GO:0009889 membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 C2H2 zinc finger transcription factor#PC00248;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8028501|UniProtKB=A0ACM8FRG5 A0ACM8FRG5 TBCD PTHR12658:SF1 BETA-TUBULIN COFACTOR D TUBULIN-SPECIFIC CHAPERONE D binding#GO:0005488;molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;protein binding#GO:0005515;tubulin binding#GO:0015631;cytoskeletal protein binding#GO:0008092;enzyme activator activity#GO:0008047;molecular function regulator activity#GO:0098772;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 cell junction organization#GO:0034330;protein folding#GO:0006457;cellular component organization#GO:0016043;primary metabolic process#GO:0044238;adherens junction organization#GO:0034332;cell junction assembly#GO:0034329;protein metabolic process#GO:0019538;microtubule cytoskeleton organization#GO:0000226;protein maturation#GO:0051604;gene expression#GO:0010467;cellular component assembly#GO:0022607;biosynthetic process#GO:0009058;cytoskeleton organization#GO:0007010;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component organization or biogenesis#GO:0071840;macromolecule metabolic process#GO:0043170;microtubule-based process#GO:0007017;metabolic process#GO:0008152;cell-cell junction assembly#GO:0007043;cell-cell junction organization#GO:0045216 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 chaperone#PC00072 IXOSC|EnsemblGenome=LOC8030244|UniProtKB=A0ACM8DQH9 A0ACM8DQH9 LOC8030244 PTHR11157:SF69 FATTY ACID ACYL TRANSFERASE-RELATED ELONGATION OF VERY LONG CHAIN FATTY ACIDS PROTEIN-RELATED catalytic activity#GO:0003824;transferase activity#GO:0016740;acyltransferase activity#GO:0016746;acyltransferase activity, transferring groups other than amino-acyl groups#GO:0016747 oxoacid metabolic process#GO:0043436;very long-chain fatty acid metabolic process#GO:0000038;small molecule metabolic process#GO:0044281;carboxylic acid biosynthetic process#GO:0046394;monocarboxylic acid metabolic process#GO:0032787;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid biosynthetic process#GO:0072330;lipid metabolic process#GO:0006629;small molecule biosynthetic process#GO:0044283;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;sphingolipid biosynthetic process#GO:0030148;fatty acid metabolic process#GO:0006631;fatty acid biosynthetic process#GO:0006633;biosynthetic process#GO:0009058;lipid biosynthetic process#GO:0008610;cellular process#GO:0009987 organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum subcompartment#GO:0098827;intracellular organelle#GO:0043229;endoplasmic reticulum#GO:0005783 acyltransferase#PC00042;transferase#PC00220 IXOSC|EnsemblGenome=LOC8023656|UniProtKB=A0ACM8E0Y5 A0ACM8E0Y5 kermit PTHR12259:SF1 RGS-GAIP INTERACTING PROTEIN GIPC GH21964P scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8027358|UniProtKB=A0ACM8DJ00 A0ACM8DJ00 LOC8027358 PTHR14689:SF0 PHORBOL-ESTER_DAG-TYPE DOMAIN-CONTAINING PROTEIN COILED-COIL DOMAIN-CONTAINING PROTEIN 82 IXOSC|EnsemblGenome=LOC8043645|UniProtKB=A0ACM8EBI1 A0ACM8EBI1 LOC8043645 PTHR24173:SF93 ANKYRIN REPEAT CONTAINING PROTEIN FEM-1 HOMOLOG CG6966 protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 metabolic process#GO:0008152;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;macromolecule catabolic process#GO:0009057;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;ubiquitin-dependent protein catabolic process#GO:0006511;primary metabolic process#GO:0044238;modification-dependent protein catabolic process#GO:0019941;cellular process#GO:0009987;catabolic process#GO:0009056;proteasomal protein catabolic process#GO:0010498 catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular protein-containing complex#GO:0140535;protein-containing complex#GO:0032991;ubiquitin ligase complex#GO:0000151 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120842361|UniProtKB=A0ACM8ETL2 A0ACM8ETL2 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8051523|UniProtKB=A0ACM8ER95 A0ACM8ER95 LOC8051523 PTHR24252:SF47 ACROSIN-RELATED TRANSMEMBRANE PROTEASE SERINE 11E-RELATED serine hydrolase activity#GO:0017171;hydrolase activity#GO:0016787;serine-type peptidase activity#GO:0008236;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;catalytic activity#GO:0003824 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 serine protease#PC00203;protease#PC00190 IXOSC|EnsemblGenome=LOC120842786|UniProtKB=A0ACM8EUG2 A0ACM8EUG2 LOC120842786 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8034040|UniProtKB=A0ACM8FZX0 A0ACM8FZX0 LOC8034040 PTHR23347:SF6 COLORECTAL MUTANT CANCER PROTEIN MCC PROTEIN -RELATED FI17904P1 IXOSC|EnsemblGenome=LOC8024148|UniProtKB=A0ACM8FZU7 A0ACM8FZU7 LOC8024148 PTHR43763:SF4 XAA-PRO AMINOPEPTIDASE 1 XAA-PRO AMINOPEPTIDASE 2 protease#PC00190 IXOSC|EnsemblGenome=LOC115324890|UniProtKB=A0ACM8FJM0 A0ACM8FJM0 LOC115324890 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8031005|UniProtKB=A0ACM8DHV7 A0ACM8DHV7 LOC8031005 PTHR12161:SF5 IST1 FAMILY MEMBER IST1 HOMOLOG localization#GO:0051179;intracellular protein localization#GO:0008104;macromolecule localization#GO:0033036 IXOSC|EnsemblGenome=LOC8032176|UniProtKB=A0ACM8EJW5 A0ACM8EJW5 PTHR11267:SF212 T-BOX PROTEIN-RELATED LP04777P-RELATED sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;transcription regulatory region nucleic acid binding#GO:0001067;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981 regulation of nucleobase-containing compound metabolic process#GO:0019219;heart development#GO:0007507;multicellular organismal process#GO:0032501;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;cellular process#GO:0009987;multicellular organism development#GO:0007275;animal organ development#GO:0048513;regulation of biosynthetic process#GO:0009889;cellular developmental process#GO:0048869;regulation of gene expression#GO:0010468;developmental process#GO:0032502;cell fate specification#GO:0001708;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;cell differentiation#GO:0030154;circulatory system development#GO:0072359;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;anatomical structure development#GO:0048856;regulation of DNA-templated transcription#GO:0006355;cell fate commitment#GO:0045165;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108 chromosome#GO:0005694;nucleus#GO:0005634;chromatin#GO:0000785;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622 immunoglobulin fold transcription factor#PC00251;Rel homology transcription factor#PC00252 IXOSC|EnsemblGenome=LOC8042040|UniProtKB=A0ACM8EKB1 A0ACM8EKB1 LOC8042040 PTHR10314:SF194 CYSTATHIONINE BETA-SYNTHASE CYSTATHIONINE BETA-SYNTHASE lyase activity#GO:0016829;carbon-oxygen lyase activity#GO:0016835;hydro-lyase activity#GO:0016836;catalytic activity#GO:0003824 sulfur compound metabolic process#GO:0006790;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;cellular process#GO:0009987;carboxylic acid biosynthetic process#GO:0046394;proteinogenic amino acid metabolic process#GO:0170039;small molecule metabolic process#GO:0044281;amino acid metabolic process#GO:0006520;biosynthetic process#GO:0009058;amino acid biosynthetic process#GO:0008652;metabolic process#GO:0008152;oxoacid metabolic process#GO:0043436;small molecule biosynthetic process#GO:0044283;proteinogenic amino acid biosynthetic process#GO:0170038 cellular anatomical structure#GO:0110165;intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737 lyase#PC00144;metabolite interconversion enzyme#PC00262 Cysteine biosynthesis#P02737>O-Acetylserine-lyase#P02887 IXOSC|EnsemblGenome=LOC115308990|UniProtKB=A0ACM8ELB3 A0ACM8ELB3 LOC115308990 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025335|UniProtKB=A0ACM8DJ66 A0ACM8DJ66 Abl PTHR24418:SF162 TYROSINE-PROTEIN KINASE TYROSINE-PROTEIN KINASE ABL phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein kinase activity#GO:0004672;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;catalytic activity#GO:0003824;protein tyrosine kinase activity#GO:0004713;kinase activity#GO:0016301;transferase activity, transferring phosphorus-containing groups#GO:0016772 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 non-receptor tyrosine protein kinase#PC00168 IXOSC|EnsemblGenome=LOC120846791|UniProtKB=A0ACM8F382 A0ACM8F382 LOC120846791 PTHR11505:SF210 L1 TRANSPOSABLE ELEMENT-RELATED UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN cellular process#GO:0009987 ribonucleoprotein complex#GO:1990904;protein-containing complex#GO:0032991 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC115317430|UniProtKB=A0ACM8FBH5 A0ACM8FBH5 LOC115317430 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;metallopeptidase activity#GO:0008237;catalytic activity#GO:0003824 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;macromolecule biosynthetic process#GO:0009059;protein processing#GO:0016485;cellular process#GO:0009987;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;gene expression#GO:0010467;protein maturation#GO:0051604 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC8033510|UniProtKB=A0ACM8EJG3 A0ACM8EJG3 mRpS26 PTHR21035:SF2 28S RIBOSOMAL PROTEIN S26, MITOCHONDRIAL SMALL RIBOSOMAL SUBUNIT PROTEIN MS26 membrane-enclosed lumen#GO:0031974;ribosomal subunit#GO:0044391;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737;protein-containing complex#GO:0032991;mitochondrial protein-containing complex#GO:0098798;mitochondrial small ribosomal subunit#GO:0005763;membraneless organelle#GO:0043228;mitochondrion#GO:0005739;ribosome#GO:0005840;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;small ribosomal subunit#GO:0015935;mitochondrial matrix#GO:0005759;ribonucleoprotein complex#GO:1990904;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;mitochondrial ribosome#GO:0005761;organellar ribosome#GO:0000313 translational protein#PC00263;ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115312275|UniProtKB=A0ACM8FA50 A0ACM8FA50 LOC115312275 PTHR37984:SF31 PROTEIN CBG26694 INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120840201|UniProtKB=A0ACM8FEH5 A0ACM8FEH5 LOC120840201 PTHR19446:SF483 REVERSE TRANSCRIPTASES LRRGT00075 viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC121046870|UniProtKB=A0ACM8FXQ3 A0ACM8FXQ3 LOC121046870 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC115311167|UniProtKB=A0ACM8F9K8 A0ACM8F9K8 LOC115311167 PTHR10283:SF140 SOLUTE CARRIER FAMILY 13 MEMBER PROTEIN I'M NOT DEAD YET-RELATED carboxylic acid transmembrane transporter activity#GO:0046943;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;C4-dicarboxylate transmembrane transporter activity#GO:0015556;citrate transmembrane transporter activity#GO:0015137;succinate transmembrane transporter activity#GO:0015141;dicarboxylic acid transmembrane transporter activity#GO:0005310 dicarboxylic acid transport#GO:0006835;succinate transport#GO:0015744;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179;C4-dicarboxylate transport#GO:0015740;carboxylic acid transport#GO:0046942;transport#GO:0006810;organic acid transport#GO:0015849;tricarboxylic acid transport#GO:0006842;citrate transport#GO:0015746 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC120838460|UniProtKB=A0ACM8EKW4 A0ACM8EKW4 PTHR23080:SF148 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023195|UniProtKB=A0ACM8DQM1 A0ACM8DQM1 LOC8023195 PTHR10829:SF23 CORTACTIN AND DREBRIN CORTACTIN, ISOFORM A binding#GO:0005488;actin binding#GO:0003779;actin filament binding#GO:0051015;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515;protein-containing complex binding#GO:0044877 regulation of actin filament length#GO:0030832;regulation of biological quality#GO:0065008;regulation of organelle organization#GO:0033043;regulation of cellular component size#GO:0032535;regulation of supramolecular fiber organization#GO:1902903;regulation of biological process#GO:0050789;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;regulation of cellular component biogenesis#GO:0044087;cell motility#GO:0048870;regulation of cellular process#GO:0050794;regulation of protein polymerization#GO:0032271;regulation of cellular component organization#GO:0051128;regulation of cytoskeleton organization#GO:0051493;regulation of actin filament-based process#GO:0032970;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;regulation of actin filament organization#GO:0110053;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;cell migration#GO:0016477;regulation of actin filament polymerization#GO:0030833 polymeric cytoskeletal fiber#GO:0099513;membraneless organelle#GO:0043228;cytoskeleton#GO:0005856;actin filament#GO:0005884;supramolecular polymer#GO:0099081;supramolecular complex#GO:0099080;cytoplasm#GO:0005737;cortical actin cytoskeleton#GO:0030864;intracellular membraneless organelle#GO:0043232;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944;site of polarized growth#GO:0030427;intracellular anatomical structure#GO:0005622;supramolecular fiber#GO:0099512;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cortical cytoskeleton#GO:0030863;actin cytoskeleton#GO:0015629;cell cortex#GO:0005938 cytoskeletal protein#PC00085;non-motor actin binding protein#PC00165 IXOSC|EnsemblGenome=LOC120840006|UniProtKB=A0ACM8ENK3 A0ACM8ENK3 LOC120840006 PTHR37984:SF35 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8026475|UniProtKB=A0ACM8DUF0 A0ACM8DUF0 LOC8026475 PTHR12029:SF11 RNA METHYLTRANSFERASE TRNA (GUANOSINE(18)-2'-O)-METHYLTRANSFERASE TARBP1 methyltransferase activity#GO:0008168;S-adenosylmethionine-dependent methyltransferase activity#GO:0008757;tRNA (guanine) methyltransferase activity#GO:0016423;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity#GO:0003824;transferase activity#GO:0016740;tRNA methyltransferase activity#GO:0008175;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 tRNA modification#GO:0006400;RNA biosynthetic process#GO:0032774;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA methylation#GO:0001510;RNA metabolic process#GO:0016070;methylation#GO:0032259;macromolecule modification#GO:0043412;RNA modification#GO:0009451;nucleic acid biosynthetic process#GO:0141187;macromolecule methylation#GO:0043414;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;tRNA methylation#GO:0030488;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;macromolecule metabolic process#GO:0043170;tRNA processing#GO:0008033;tRNA metabolic process#GO:0006399;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152 RNA metabolism protein#PC00031;RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC8053139|UniProtKB=A0ACM8ENA3 A0ACM8ENA3 LOC8053139 PTHR11675:SF43 N-ACETYLGALACTOSAMINYLTRANSFERASE POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE 1 transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;UDP-glycosyltransferase activity#GO:0008194;catalytic activity, acting on a protein#GO:0140096;glycosyltransferase activity#GO:0016757;acetylgalactosaminyltransferase activity#GO:0008376;polypeptide N-acetylgalactosaminyltransferase activity#GO:0004653 glycoprotein biosynthetic process#GO:0009101;primary metabolic process#GO:0044238;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;protein O-linked glycosylation#GO:0006493;biosynthetic process#GO:0009058;metabolic process#GO:0008152;glycoprotein metabolic process#GO:0009100;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;carbohydrate derivative biosynthetic process#GO:1901137 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;Golgi apparatus#GO:0005794;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 glycosyltransferase#PC00111;transferase#PC00220 IXOSC|EnsemblGenome=LOC120846835|UniProtKB=A0ACM8F328 A0ACM8F328 LOC120846835 PTHR13794:SF58 ENOLASE SUPERFAMILY, MANDELATE RACEMASE MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1 epimerase/racemase#PC00096 IXOSC|EnsemblGenome=LOC8029941|UniProtKB=A0ACM8DJ34 A0ACM8DJ34 LOC8029941 PTHR12315:SF0 BICOID-INTERACTING PROTEIN RELATED 7SK SNRNA METHYLPHOSPHATE CAPPING ENZYME methyltransferase activity#GO:0008168;binding#GO:0005488;nucleic acid binding#GO:0003676;O-methyltransferase activity#GO:0008171;RNA binding#GO:0003723;snRNA binding#GO:0017069;transferase activity, transferring one-carbon groups#GO:0016741;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;transferase activity#GO:0016740;catalytic activity, acting on RNA#GO:0140098;RNA methyltransferase activity#GO:0008173 nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;snRNA metabolic process#GO:0016073;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;macromolecule metabolic process#GO:0043170;snRNA processing#GO:0016180;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;biosynthetic process#GO:0009058 IXOSC|EnsemblGenome=LOC8051456|UniProtKB=A0ACM8DPZ2 A0ACM8DPZ2 LOC8051456 PTHR46059:SF1 BETA-GALACTOSIDE ALPHA-2,6-SIALYLTRANSFERASE BETA-GALACTOSIDE ALPHA-(2,6)-SIALYLTRANSFERASE transferase#PC00220;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8034788|UniProtKB=A0ACM8FTJ8 A0ACM8FTJ8 GABA-B-R2 PTHR10519:SF74 GABA-B RECEPTOR GAMMA-AMINOBUTYRIC ACID TYPE B RECEPTOR SUBUNIT 2 signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930;transmembrane signaling receptor activity#GO:0004888 regulation of biological process#GO:0050789;cellular process#GO:0009987;biological regulation#GO:0065007;cell-cell signaling#GO:0007267;signaling#GO:0023052;cell communication#GO:0007154 signaling receptor complex#GO:0043235;plasma membrane protein complex#GO:0098797;cell periphery#GO:0071944;membrane protein complex#GO:0098796;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 G-protein coupled receptor#PC00021 GABA-B receptor II signaling#P05731>GABA-B receptor#P05756 IXOSC|EnsemblGenome=LOC121837242|UniProtKB=A0ACM8G2X9 A0ACM8G2X9 LOC121837242 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 DNA binding#GO:0003677;binding#GO:0005488;nucleic acid binding#GO:0003676 nucleus#GO:0005634;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8025309|UniProtKB=A0ACM8FFW6 A0ACM8FFW6 LOC8025309 PTHR30575:SF0 PEPTIDASE M20 XAA-ARG DIPEPTIDASE peptidase activity#GO:0008233;exopeptidase activity#GO:0008238;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;catalytic activity#GO:0003824 oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid catabolic process#GO:0046395;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;small molecule catabolic process#GO:0044282;catabolic process#GO:0009056;small molecule metabolic process#GO:0044281;pteridine-containing compound metabolic process#GO:0042558;folic acid-containing compound metabolic process#GO:0006760 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120848430|UniProtKB=A0ACM8FWP8 A0ACM8FWP8 LOC120848430 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transporter#PC00227 IXOSC|EnsemblGenome=LOC121835618|UniProtKB=A0ACM8FV72 A0ACM8FV72 LOC121835618 PTHR23080:SF152 THAP DOMAIN PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8050782|UniProtKB=A0ACM8EI41 A0ACM8EI41 LOC8050782 PTHR24223:SF465 ATP-BINDING CASSETTE SUB-FAMILY C ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 9 transport#GO:0006810;cellular process#GO:0009987;establishment of localization#GO:0051234;transmembrane transport#GO:0055085;localization#GO:0051179 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 ATP-binding cassette (ABC) transporter#PC00003 IXOSC|EnsemblGenome=LOC121047798|UniProtKB=A0ACM8FR78 A0ACM8FR78 LOC121047798 PTHR33964:SF1 RE45066P-RELATED RE45066P IXOSC|EnsemblGenome=LOC120838632|UniProtKB=A0ACM8EKC1 A0ACM8EKC1 LOC120838632 PTHR22930:SF85 FAMILY NOT NAMED LD12639P-RELATED IXOSC|EnsemblGenome=LOC8023734|UniProtKB=A0ACM8DTW3 A0ACM8DTW3 LOC8023734 PTHR45721:SF11 LAMIN DM0-RELATED LAMIN-RELATED structural constituent of cytoskeleton#GO:0005200;structural molecule activity#GO:0005198 localization#GO:0051179;organelle localization#GO:0051640;localization within membrane#GO:0051668;regulation of macromolecule metabolic process#GO:0060255;protein localization to organelle#GO:0033365;regulation of cellular process#GO:0050794;heterochromatin formation#GO:0031507;nuclear migration#GO:0007097;establishment of localization#GO:0051234;nucleus organization#GO:0006997;regulation of biosynthetic process#GO:0009889;intracellular protein localization#GO:0008104;regulation of gene expression#GO:0010468;nuclear envelope organization#GO:0006998;intracellular transport#GO:0046907;negative regulation of cellular process#GO:0048523;transport#GO:0006810;membrane organization#GO:0061024;negative regulation of biosynthetic process#GO:0009890;biological regulation#GO:0065007;chromatin organization#GO:0006325;macromolecule localization#GO:0033036;regulation of metabolic process#GO:0019222;protein localization to nucleus#GO:0034504;regulation of macromolecule biosynthetic process#GO:0010556;epigenetic regulation of gene expression#GO:0040029;negative regulation of macromolecule metabolic process#GO:0010605;cellular localization#GO:0051641;establishment of organelle localization#GO:0051656;negative regulation of metabolic process#GO:0009892;chromatin remodeling#GO:0006338;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;regulation of biological process#GO:0050789;cellular component organization or biogenesis#GO:0071840;negative regulation of gene expression, epigenetic#GO:0045814;cellular component assembly#GO:0022607;endomembrane system organization#GO:0010256;heterochromatin organization#GO:0070828;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;establishment of localization in cell#GO:0051649;cellular process#GO:0009987 nuclear periphery#GO:0034399;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;organelle lumen#GO:0043233;membrane-enclosed lumen#GO:0031974;organelle envelope#GO:0031967;nucleus#GO:0005634;endomembrane system#GO:0012505;nuclear lumen#GO:0031981;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;nuclear envelope#GO:0005635 FAS signaling pathway#P00020>Nuclear Lamin#P00616 IXOSC|EnsemblGenome=LOC120841577|UniProtKB=A0ACM8FPQ7 A0ACM8FPQ7 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8024689|UniProtKB=A0ACM8F2I0 A0ACM8F2I0 LOC8024689 PTHR23142:SF2 PRE-MRNA-SPLICING FACTOR 38A-RELATED PRE-MRNA-SPLICING FACTOR 38B macromolecule metabolic process#GO:0043170;RNA splicing#GO:0008380;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;mRNA processing#GO:0006397;RNA metabolic process#GO:0016070;RNA splicing, via transesterification reactions with bulged adenosine as nucleophile#GO:0000377;nucleic acid biosynthetic process#GO:0141187;RNA splicing, via transesterification reactions#GO:0000375;RNA biosynthetic process#GO:0032774;mRNA metabolic process#GO:0016071;mRNA splicing, via spliceosome#GO:0000398;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304 cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;spliceosomal complex#GO:0005681;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;precatalytic spliceosome#GO:0071011;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8054026|UniProtKB=A0ACM8E8V1 A0ACM8E8V1 LOC8054026 PTHR10026:SF144 CYCLIN CYCLIN-K molecular function activator activity#GO:0140677;enzyme regulator activity#GO:0030234;kinase activator activity#GO:0019209;cyclin-dependent protein kinase regulator activity#GO:0019914;protein kinase regulator activity#GO:0019887;molecular function regulator activity#GO:0098772;kinase regulator activity#GO:0019207;protein kinase activator activity#GO:0030295;enzyme activator activity#GO:0008047;protein serine/threonine kinase activator activity#GO:0043539;cyclin-dependent protein serine/threonine kinase regulator activity#GO:0016538 regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;positive regulation of transcription by RNA polymerase II#GO:0045944;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of macromolecule metabolic process#GO:0010604;positive regulation of RNA biosynthetic process#GO:1902680;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription elongation#GO:0032784;regulation of cellular process#GO:0050794;positive regulation of DNA-templated transcription, elongation#GO:0032786;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of RNA metabolic process#GO:0051254;regulation of biological process#GO:0050789 transferase complex, transferring phosphorus-containing groups#GO:0061695;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;membrane-bounded organelle#GO:0043227;serine/threonine protein kinase complex#GO:1902554;intracellular anatomical structure#GO:0005622;organelle lumen#GO:0043233;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;transcription elongation factor complex#GO:0008023;intracellular membrane-bounded organelle#GO:0043231;transferase complex#GO:1990234;nuclear protein-containing complex#GO:0140513;protein kinase complex#GO:1902911;membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;cyclin-dependent protein kinase holoenzyme complex#GO:0000307 kinase activator#PC00138;kinase modulator#PC00140 Cell cycle#P00013>CdkC#P00489 IXOSC|EnsemblGenome=LOC8038680|UniProtKB=A0ACM8E2D4 A0ACM8E2D4 LOC8038680 PTHR45904:SF1 TRNA (URACIL-5-)-METHYLTRANSFERASE TRNA (URACIL-5-)-METHYLTRANSFERASE HOMOLOG B RNA methyltransferase#PC00033 IXOSC|EnsemblGenome=LOC120843961|UniProtKB=A0ACM8EXB6 A0ACM8EXB6 LOC120843961 PTHR37984:SF37 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115321640|UniProtKB=A0ACM8E2E0 A0ACM8E2E0 LOC115321640 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8035427|UniProtKB=A0ACM8DJT6 A0ACM8DJT6 LOC8035427 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED carbon-carbon lyase activity#GO:0016830;catalytic activity#GO:0003824;carboxy-lyase activity#GO:0016831;ornithine decarboxylase activity#GO:0004586;lyase activity#GO:0016829 polyamine metabolic process#GO:0006595;cellular process#GO:0009987;metabolic process#GO:0008152;amine metabolic process#GO:0009308;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058;polyamine biosynthetic process#GO:0006596 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165 metabolite interconversion enzyme#PC00262;decarboxylase#PC00089 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC8041145|UniProtKB=A0ACM8EI23 A0ACM8EI23 LOC8041145 PTHR46102:SF2 AXIN AXIN beta-catenin binding#GO:0008013;protein binding#GO:0005515;protein kinase binding#GO:0019901;enzyme binding#GO:0019899;binding#GO:0005488;kinase binding#GO:0019900;ubiquitin protein ligase binding#GO:0031625;ubiquitin-like protein ligase binding#GO:0044389 anatomical structure development#GO:0048856;regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032434;regulation of protein catabolic process#GO:0042176;positive regulation of protein catabolic process#GO:0045732;positive regulation of ubiquitin-dependent protein catabolic process#GO:2000060;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;regulation of cell communication#GO:0010646;negative regulation of cellular process#GO:0048523;regulation of response to stimulus#GO:0048583;developmental process#GO:0032502;cellular developmental process#GO:0048869;positive regulation of catabolic process#GO:0009896;regulation of catabolic process#GO:0009894;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090;positive regulation of cellular process#GO:0048522;negative regulation of Wnt signaling pathway#GO:0030178;negative regulation of response to stimulus#GO:0048585;biological regulation#GO:0065007;regulation of signal transduction#GO:0009966;negative regulation of canonical Wnt signaling pathway#GO:0090090;negative regulation of signaling#GO:0023057;regulation of signaling#GO:0023051;positive regulation of protein metabolic process#GO:0051247;positive regulation of metabolic process#GO:0009893;negative regulation of cell communication#GO:0010648;negative regulation of biological process#GO:0048519;positive regulation of proteasomal protein catabolic process#GO:1901800;regulation of biological process#GO:0050789;cell differentiation#GO:0030154;cell development#GO:0048468;regulation of Wnt signaling pathway#GO:0030111;regulation of ubiquitin-dependent protein catabolic process#GO:2000058;regulation of protein metabolic process#GO:0051246;regulation of canonical Wnt signaling pathway#GO:0060828;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;positive regulation of macromolecule metabolic process#GO:0010604;regulation of proteasomal protein catabolic process#GO:0061136;negative regulation of signal transduction#GO:0009968;positive regulation of proteasomal ubiquitin-dependent protein catabolic process#GO:0032436 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;intracellular anatomical structure#GO:0005622;intracellular protein-containing complex#GO:0140535;membrane-bounded organelle#GO:0043227;membrane#GO:0016020;nucleus#GO:0005634;cell periphery#GO:0071944;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;plasma membrane#GO:0005886 scaffold/adaptor protein#PC00226 Angiogenesis#P00005>Axin#P00253;Wnt signaling pathway#P00057>Axin#P01429;Wnt signaling pathway#P00057>Wnt Target Genes#G01558 IXOSC|EnsemblGenome=LOC8052910|UniProtKB=A0ACM8DUS5 A0ACM8DUS5 LOC8052910 PTHR14649:SF1 ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C ZINC FINGER C2HC DOMAIN-CONTAINING PROTEIN 1C IXOSC|EnsemblGenome=LOC8026594|UniProtKB=A0ACM8E7K3 A0ACM8E7K3 LOC8026594 PTHR43201:SF5 ACYL-COA SYNTHETASE MEDIUM-CHAIN ACYL-COA LIGASE ACSF2, MITOCHONDRIAL ligase activity, forming carbon-sulfur bonds#GO:0016877;catalytic activity#GO:0003824;ligase activity#GO:0016874;ATP-dependent activity#GO:0140657 small molecule metabolic process#GO:0044281;cellular process#GO:0009987;carboxylic acid metabolic process#GO:0019752;primary metabolic process#GO:0044238;monocarboxylic acid metabolic process#GO:0032787;lipid metabolic process#GO:0006629;fatty acid metabolic process#GO:0006631;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152 ligase#PC00142;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC115314443|UniProtKB=A0ACM8EWE0 A0ACM8EWE0 LOC115314443 PTHR24252:SF40 ACROSIN-RELATED BRAIN-SPECIFIC SERINE PROTEASE 4 catalytic activity, acting on a protein#GO:0140096;serine-type endopeptidase activity#GO:0004252;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;catalytic activity#GO:0003824;hydrolase activity#GO:0016787;serine hydrolase activity#GO:0017171;serine-type peptidase activity#GO:0008236 catabolic process#GO:0009056;cellular process#GO:0009987;primary metabolic process#GO:0044238;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057 protease#PC00190;serine protease#PC00203 IXOSC|EnsemblGenome=LOC120846138|UniProtKB=A0ACM8F1M2 A0ACM8F1M2 LOC120846138 PTHR19303:SF73 TRANSPOSON PROTEIN PDC2 binding#GO:0005488;nucleic acid binding#GO:0003676;DNA binding#GO:0003677 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;intracellular organelle#GO:0043229;nucleus#GO:0005634 viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC121837862|UniProtKB=A0ACM8G5G6 A0ACM8G5G6 LOC121837862 PTHR46600:SF11 THAP DOMAIN-CONTAINING THAP DOMAIN-CONTAINING PROTEIN 10 zinc finger transcription factor#PC00244;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8023746|UniProtKB=A0ACM8FGG7 A0ACM8FGG7 svp PTHR24083:SF46 NUCLEAR HORMONE RECEPTOR STEROID RECEPTOR SEVEN-UP, ISOFORM A sequence-specific double-stranded DNA binding#GO:1990837;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;transcription cis-regulatory region binding#GO:0000976;DNA binding#GO:0003677;nuclear receptor activity#GO:0004879;cis-regulatory region sequence-specific DNA binding#GO:0000987;molecular transducer activity#GO:0060089;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;signaling receptor activity#GO:0038023;sequence-specific DNA binding#GO:0043565;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110;transcription regulatory region nucleic acid binding#GO:0001067 cell differentiation#GO:0030154;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;biological regulation#GO:0065007;regulation of RNA biosynthetic process#GO:2001141;nervous system development#GO:0007399;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987;multicellular organism development#GO:0007275;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;developmental process#GO:0032502 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 C4 zinc finger nuclear receptor#PC00169;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8030864|UniProtKB=A0ACM8DPY0 A0ACM8DPY0 TBC1D5 PTHR22957:SF337 TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN TBC1 DOMAIN FAMILY MEMBER 5 enzyme activator activity#GO:0008047;molecular function activator activity#GO:0140677;molecular function regulator activity#GO:0098772;enzyme regulator activity#GO:0030234;GTPase activator activity#GO:0005096;GTPase regulator activity#GO:0030695;nucleoside-triphosphatase regulator activity#GO:0060589 vesicle-mediated transport#GO:0016192;cytosolic transport#GO:0016482;retrograde transport, endosome to Golgi#GO:0042147;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;establishment of localization#GO:0051234;cellular localization#GO:0051641;localization#GO:0051179;endosomal transport#GO:0016197;intracellular transport#GO:0046907;transport#GO:0006810 organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;Golgi apparatus#GO:0005794;endomembrane system#GO:0012505;cytoplasmic vesicle membrane#GO:0030659;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;vesicle membrane#GO:0012506;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768;endosome membrane#GO:0010008;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;retromer complex#GO:0030904;vesicle#GO:0031982 protein-binding activity modulator#PC00095;G-protein modulator#PC00022;GTPase-activating protein#PC00257 IXOSC|EnsemblGenome=LOC121835138|UniProtKB=A0ACM8FRN9 A0ACM8FRN9 LOC121835138 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8031283|UniProtKB=A0ACM8E7G4 A0ACM8E7G4 LOC8031283 PTHR31179:SF7 RAB GTPASE-BINDING EFFECTOR PROTEIN RAB GTPASE-BINDING EFFECTOR PROTEIN 1 intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229 IXOSC|EnsemblGenome=LOC8040577|UniProtKB=A0ACM8DKM0 A0ACM8DKM0 LOC8040577 PTHR13466:SF0 TEX2 PROTEIN-RELATED SMP-LTD DOMAIN-CONTAINING PROTEIN lipid binding#GO:0008289;binding#GO:0005488 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226 IXOSC|EnsemblGenome=LOC115309099|UniProtKB=A0ACM8EYQ2 A0ACM8EYQ2 LOC115309099 PTHR10264:SF136 BAND 7 PROTEIN-RELATED BAND 7 DOMAIN-CONTAINING PROTEIN molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247;molecular function inhibitor activity#GO:0140678;transporter regulator activity#GO:0141108;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC120841434|UniProtKB=A0ACM8ER81 A0ACM8ER81 LOC120841434 PTHR23080:SF146 THAP DOMAIN PROTEIN SI:DKEY-56D12.4 IXOSC|EnsemblGenome=LOC121835516|UniProtKB=A0ACM8FVI2 A0ACM8FVI2 LOC121835516 PTHR22930:SF307 FAMILY NOT NAMED DDE TNP4 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC115310173|UniProtKB=A0ACM8DPD5 A0ACM8DPD5 LOC115310173 PTHR45828:SF53 CYTOCHROME B561/FERRIC REDUCTASE TRANSMEMBRANE SECRETED PROTEIN cellular anatomical structure#GO:0110165;membrane#GO:0016020 oxidoreductase#PC00176;reductase#PC00198 IXOSC|EnsemblGenome=LOC8052045|UniProtKB=A0ACM8EE55 A0ACM8EE55 Gyc88E PTHR45655:SF20 GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 SOLUBLE GUANYLATE CYCLASE 88E small molecule binding#GO:0036094;binding#GO:0005488;lyase activity#GO:0016829;phosphorus-oxygen lyase activity#GO:0016849;cyclase activity#GO:0009975;catalytic activity#GO:0003824;molecular function regulator activity#GO:0098772;molecular sensor activity#GO:0140299;guanylate cyclase activity#GO:0004383 cell communication#GO:0007154;intracellular signal transduction#GO:0035556;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;signaling#GO:0023052;biological regulation#GO:0065007;intracellular signaling cassette#GO:0141124;response to oxygen levels#GO:0070482;response to abiotic stimulus#GO:0009628;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular process#GO:0009987;cellular response to stimulus#GO:0051716 catalytic complex#GO:1902494;cytosol#GO:0005829;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165 cyclase#PC00079;guanylate cyclase#PC00114 IXOSC|EnsemblGenome=LOC120847912|UniProtKB=A0ACM8F5X8 A0ACM8F5X8 LOC120847912 PTHR21505:SF12 MADF DOMAIN-CONTAINING PROTEIN-RELATED MADF DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8043760|UniProtKB=A0ACM8G0U0 A0ACM8G0U0 LOC8043760 PTHR46079:SF2 FERM DOMAIN-CONTAINING PROTEIN 4 FERM DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC121047154|UniProtKB=A0ACM8FQE0 A0ACM8FQE0 PTHR34153:SF4 SI:CH211-262H13.3-RELATED-RELATED DUF4806 DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC120837637|UniProtKB=A0ACM8G208 A0ACM8G208 LOC120837637 PTHR19324:SF33 PERFORIN-LIKE PROTEIN 1 MUCIN-5AC IXOSC|EnsemblGenome=LOC8025293|UniProtKB=A0ACM8G5X5 A0ACM8G5X5 LOC8025293 PTHR15819:SF11 TRANSMEMBRANE PROTEIN FAM155 MID1, ISOFORM A transporter regulator activity#GO:0141108;molecular function regulator activity#GO:0098772;channel regulator activity#GO:0016247 localization#GO:0051179;establishment of localization#GO:0051234;import into cell#GO:0098657;transmembrane transport#GO:0055085;inorganic cation import across plasma membrane#GO:0098659;transport#GO:0006810;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;cellular process#GO:0009987 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC8024699|UniProtKB=A0ACM8G4D3 A0ACM8G4D3 LOC8024699 PTHR24393:SF175 ZINC FINGER PROTEIN C2H2-TYPE DOMAIN-CONTAINING PROTEIN transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;double-stranded DNA binding#GO:0003690;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA binding#GO:0003677;cis-regulatory region sequence-specific DNA binding#GO:0000987;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;DNA-binding transcription activator activity#GO:0001216;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription regulatory region nucleic acid binding#GO:0001067;DNA-binding transcription activator activity, RNA polymerase II-specific#GO:0001228;sequence-specific DNA binding#GO:0043565 regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of transcription by RNA polymerase II#GO:0006357;regulation of macromolecule metabolic process#GO:0060255;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;regulation of biological process#GO:0050789 intracellular organelle#GO:0043229;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165 C2H2 zinc finger transcription factor#PC00248;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8036906|UniProtKB=A0ACM8G736 A0ACM8G736 dlg1 PTHR23119:SF51 DISCS LARGE DISKS LARGE 1 TUMOR SUPPRESSOR PROTEIN protein binding#GO:0005515;binding#GO:0005488;kinase binding#GO:0019900;protein kinase binding#GO:0019901;enzyme binding#GO:0019899 multicellular organismal process#GO:0032501;cell-cell signaling#GO:0007267;biological regulation#GO:0065007;macromolecule localization#GO:0033036;intracellular protein localization#GO:0008104;regulation of postsynaptic membrane neurotransmitter receptor levels#GO:0099072;developmental process#GO:0032502;anterograde trans-synaptic signaling#GO:0098916;chemical synaptic transmission#GO:0007268;establishment or maintenance of epithelial cell apical/basal polarity#GO:0045197;localization#GO:0051179;cell communication#GO:0007154;anatomical structure development#GO:0048856;system development#GO:0048731;protein localization to cell junction#GO:1902414;trans-synaptic signaling#GO:0099537;establishment or maintenance of apical/basal cell polarity#GO:0035088;localization within membrane#GO:0051668;establishment or maintenance of bipolar cell polarity#GO:0061245;nervous system development#GO:0007399;cell-cell adhesion#GO:0098609;synaptic signaling#GO:0099536;cellular process#GO:0009987;protein localization to synapse#GO:0035418;multicellular organism development#GO:0007275;signaling#GO:0023052;protein localization to membrane#GO:0072657;regulation of biological process#GO:0050789;cellular localization#GO:0051641;regulation of biological quality#GO:0065008;establishment or maintenance of cell polarity#GO:0007163;animal gross anatomical part developmental process#GO:0160108;cell adhesion#GO:0007155;receptor clustering#GO:0043113 postsynaptic density#GO:0014069;postsynaptic membrane#GO:0045211;postsynaptic specialization membrane#GO:0099634;postsynaptic density membrane#GO:0098839;postsynapse#GO:0098794;cell projection#GO:0042995;plasma membrane bounded cell projection#GO:0120025;organelle#GO:0043226;asymmetric synapse#GO:0032279;synapse#GO:0045202;cellular anatomical structure#GO:0110165;synaptic membrane#GO:0097060;cell junction#GO:0030054;neuromuscular junction#GO:0031594;neuron projection#GO:0043005;cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;plasma membrane region#GO:0098590;postsynaptic specialization#GO:0099572;neuron to neuron synapse#GO:0098984 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8051659|UniProtKB=A0ACM8DLC5 A0ACM8DLC5 Hsc70-3 PTHR19375:SF144 HEAT SHOCK PROTEIN 70KDA ENDOPLASMIC RETICULUM CHAPERONE BIP ribonucleoside triphosphate phosphatase activity#GO:0017111;pyrophosphatase activity#GO:0016462;catalytic activity#GO:0003824;hydrolase activity, acting on acid anhydrides#GO:0016817;heat shock protein binding#GO:0031072;hydrolase activity#GO:0016787;protein binding#GO:0005515;ATP hydrolysis activity#GO:0016887;binding#GO:0005488;hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides#GO:0016818;ATP-dependent activity#GO:0140657 protein folding#GO:0006457;signaling#GO:0023052;response to topologically incorrect protein#GO:0035966;response to stimulus#GO:0050896;regulation of biological process#GO:0050789;protein refolding#GO:0042026;response to unfolded protein#GO:0006986;cellular response to stress#GO:0033554;protein catabolic process#GO:0030163;proteasomal protein catabolic process#GO:0010498;gene expression#GO:0010467;protein maturation#GO:0051604;response to chemical#GO:0042221;cellular process#GO:0009987;signal transduction#GO:0007165;response to stress#GO:0006950;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;regulation of cellular process#GO:0050794;catabolic process#GO:0009056;cellular response to stimulus#GO:0051716;primary metabolic process#GO:0044238;intracellular signal transduction#GO:0035556;ERAD pathway#GO:0036503;protein metabolic process#GO:0019538;cell communication#GO:0007154;cellular response to topologically incorrect protein#GO:0035967;cellular response to unfolded protein#GO:0034620;response to endoplasmic reticulum stress#GO:0034976;biological regulation#GO:0065007;biosynthetic process#GO:0009058;macromolecule biosynthetic process#GO:0009059;endoplasmic reticulum unfolded protein response#GO:0030968;macromolecule metabolic process#GO:0043170 endoplasmic reticulum protein-containing complex#GO:0140534;endoplasmic reticulum#GO:0005783;endomembrane system#GO:0012505;protein-containing complex#GO:0032991;cytoplasm#GO:0005737;membrane-enclosed lumen#GO:0031974;membrane#GO:0016020;endoplasmic reticulum lumen#GO:0005788;nucleus#GO:0005634;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle lumen#GO:0070013;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;organelle lumen#GO:0043233 chaperone#PC00072;Hsp70 family chaperone#PC00027 Apoptosis signaling pathway#P00006>HSP70#P00321;Parkinson disease#P00049>Hsp70#P01208 IXOSC|EnsemblGenome=LOC115319175|UniProtKB=A0ACM8FA13 A0ACM8FA13 LOC115319175 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788 metabolic process#GO:0008152;primary metabolic process#GO:0044238;lipid metabolic process#GO:0006629;cellular process#GO:0009987 lipase#PC00143;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115310243|UniProtKB=A0ACM8EZF6 A0ACM8EZF6 LOC115310243 PTHR10083:SF374 KUNITZ-TYPE PROTEASE INHIBITOR-RELATED SERINE PEPTIDASE INHIBITOR, KUNITZ TYPE, 3 enzyme inhibitor activity#GO:0004857;molecular function regulator activity#GO:0098772;endopeptidase inhibitor activity#GO:0004866;peptidase regulator activity#GO:0061134;peptidase inhibitor activity#GO:0030414;endopeptidase regulator activity#GO:0061135;serine-type endopeptidase inhibitor activity#GO:0004867;molecular function inhibitor activity#GO:0140678;enzyme regulator activity#GO:0030234 protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8041726|UniProtKB=A0ACM8E3W1 A0ACM8E3W1 LOC8041726 PTHR15840:SF10 CGI-121 FAMILY MEMBER EKC_KEOPS COMPLEX SUBUNIT TPRKB nucleic acid biosynthetic process#GO:0141187;RNA modification#GO:0009451;RNA metabolic process#GO:0016070;macromolecule modification#GO:0043412;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;RNA biosynthetic process#GO:0032774;tRNA modification#GO:0006400;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;tRNA metabolic process#GO:0006399;tRNA processing#GO:0008033;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;biosynthetic process#GO:0009058;nucleobase-containing compound metabolic process#GO:0006139;RNA processing#GO:0006396;gene expression#GO:0010467 cytosol#GO:0005829;nucleus#GO:0005634;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;intracellular organelle#GO:0043229;catalytic complex#GO:1902494;transferase complex#GO:1990234;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 IXOSC|EnsemblGenome=LOC120841385|UniProtKB=A0ACM8ERF9 A0ACM8ERF9 PTHR19282:SF551 TETRASPANIN TETRASPANIN-RELATED plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC115313676|UniProtKB=A0ACM8EWU7 A0ACM8EWU7 LOC115313676 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121837400|UniProtKB=A0ACM8G4T0 A0ACM8G4T0 LOC121837400 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxygenase#PC00177;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115318303|UniProtKB=A0ACM8EUV8 A0ACM8EUV8 LOC115318303 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115332422|UniProtKB=A0ACM8EDN9 A0ACM8EDN9 LOC115332422 PTHR24388:SF53 ZINC FINGER PROTEIN AT-RICH BINDING PROTEIN-RELATED sequence-specific DNA binding#GO:0043565;sequence-specific double-stranded DNA binding#GO:1990837;transcription regulator activity#GO:0140110;transcription cis-regulatory region binding#GO:0000976;nucleic acid binding#GO:0003676;binding#GO:0005488;DNA-binding transcription factor activity#GO:0003700;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;RNA polymerase II cis-regulatory region sequence-specific DNA binding#GO:0000978;DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;double-stranded DNA binding#GO:0003690;DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;cis-regulatory region sequence-specific DNA binding#GO:0000987 regulation of RNA metabolic process#GO:0051252;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of biological process#GO:0050789;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;regulation of primary metabolic process#GO:0080090 organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;nucleus#GO:0005634 gene-specific transcriptional regulator#PC00264;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC121836631|UniProtKB=A0ACM8FYZ2 A0ACM8FYZ2 LOC121836631 PTHR11005:SF161 LYSOSOMAL ACID LIPASE-RELATED LIPASE catalytic activity#GO:0003824;lipase activity#GO:0016298;hydrolase activity, acting on ester bonds#GO:0016788;hydrolase activity#GO:0016787 lipid metabolic process#GO:0006629;cellular process#GO:0009987;primary metabolic process#GO:0044238;metabolic process#GO:0008152 hydrolase#PC00121;lipase#PC00143 IXOSC|EnsemblGenome=LOC8028797|UniProtKB=A0ACM8DH73 A0ACM8DH73 LOC8028797 PTHR23259:SF70 RIDDLE ACCESSORY GLAND PROTEIN ACP62F-RELATED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC115309685|UniProtKB=A0ACM8DNW7 A0ACM8DNW7 PTHR47272:SF3 DDE_TNP_1_7 DOMAIN-CONTAINING PROTEIN PIGGYBAC TRANSPOSABLE ELEMENT-DERIVED PROTEIN DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034930|UniProtKB=A0ACM8FGU4 A0ACM8FGU4 LOC8034930 PTHR10278:SF0 CORTICOTROPIN-RELEASING FACTOR-BINDING PROTEIN CORTICOTROPIN-RELEASING HORMONE-BINDING PROTEIN hormone binding#GO:0042562;binding#GO:0005488;peptide hormone binding#GO:0017046 regulation of system process#GO:0044057;negative regulation of cellular process#GO:0048523;biological regulation#GO:0065007;cell communication#GO:0007154;regulation of secretion#GO:0051046;cellular response to stimulus#GO:0051716;negative regulation of multicellular organismal process#GO:0051241;regulation of cell communication#GO:0010646;negative regulation of transport#GO:0051051;regulation of cellular process#GO:0050794;regulation of localization#GO:0032879;regulation of transport#GO:0051049;signal transduction#GO:0007165;cellular process#GO:0009987;response to hormone#GO:0009725;regulation of multicellular organismal process#GO:0051239;response to chemical#GO:0042221;regulation of signaling#GO:0023051;cellular response to chemical stimulus#GO:0070887;negative regulation of signaling#GO:0023057;negative regulation of cell communication#GO:0010648;regulation of secretion by cell#GO:1903530;regulation of biological quality#GO:0065008;regulation of hormone secretion#GO:0046883;hormone-mediated signaling pathway#GO:0009755;regulation of biological process#GO:0050789;regulation of hormone levels#GO:0010817;response to endogenous stimulus#GO:0009719;negative regulation of biological process#GO:0048519;signaling#GO:0023052;response to stimulus#GO:0050896;cellular response to endogenous stimulus#GO:0071495;cellular response to hormone stimulus#GO:0032870 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 IXOSC|EnsemblGenome=LOC120846541|UniProtKB=A0ACM8FUF8 A0ACM8FUF8 LOC120846541 PTHR33332:SF48 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032793|UniProtKB=A0ACM8DGW3 A0ACM8DGW3 P32 PTHR10826:SF1 COMPLEMENT COMPONENT 1 COMPLEMENT COMPONENT 1 Q SUBCOMPONENT-BINDING PROTEIN, MITOCHONDRIAL protein-macromolecule adaptor activity#GO:0030674;molecular adaptor activity#GO:0060090;protein-RNA adaptor activity#GO:0140517 nucleic acid metabolic process#GO:0090304;primary metabolic process#GO:0044238;nucleobase-containing compound catabolic process#GO:0034655;nucleic acid catabolic process#GO:0141188;cellular process#GO:0009987;catabolic process#GO:0009056;nucleobase-containing compound metabolic process#GO:0006139;macromolecule catabolic process#GO:0009057;metabolic process#GO:0008152;RNA catabolic process#GO:0006401;RNA metabolic process#GO:0016070;mitochondrial RNA metabolic process#GO:0000959;macromolecule metabolic process#GO:0043170 cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cellular anatomical structure#GO:0110165;organelle#GO:0043226;mitochondrion#GO:0005739;membrane-enclosed lumen#GO:0031974;organelle lumen#GO:0043233;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;mitochondrial matrix#GO:0005759;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013 defense/immunity protein#PC00090;complement component#PC00078 IXOSC|EnsemblGenome=LOC8034230|UniProtKB=A0ACM8E8W7 A0ACM8E8W7 mRpL37 PTHR15889:SF2 MITOCHONDRIAL RIBOSOMAL PROTEIN L37 LARGE RIBOSOMAL SUBUNIT PROTEIN ML37 mitochondrion#GO:0005739;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 ribosomal protein#PC00202 IXOSC|EnsemblGenome=LOC115333179|UniProtKB=A0ACM8EUC2 A0ACM8EUC2 LOC115333179 PTHR47160:SF12 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8023705|UniProtKB=A0ACM8EDV5 A0ACM8EDV5 LOC8023705 PTHR14957:SF1 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10 UBIQUITIN-LIKE-CONJUGATING ENZYME ATG10 ubiquitin-like protein conjugating enzyme activity#GO:0061650;acyltransferase activity#GO:0016746;ubiquitin-like protein transferase activity#GO:0019787;catalytic activity, acting on a protein#GO:0140096;aminoacyltransferase activity#GO:0016755;Atg12 transferase activity#GO:0019777;Atg12 conjugating enzyme activity#GO:0061651;transferase activity#GO:0016740;catalytic activity#GO:0003824 autophagy of mitochondrion#GO:0000422;metabolic process#GO:0008152;mitophagy#GO:0000423;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;autophagosome assembly#GO:0000045;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;autophagosome organization#GO:1905037;cellular process#GO:0009987;autophagy#GO:0006914;cellular component assembly#GO:0022607;post-translational protein modification#GO:0043687;macroautophagy#GO:0016236;protein modification by small protein conjugation or removal#GO:0070647;organelle assembly#GO:0070925;macromolecule modification#GO:0043412;protein metabolic process#GO:0019538;process utilizing autophagic mechanism#GO:0061919;vacuole organization#GO:0007033;cellular component organization#GO:0016043;protein modification process#GO:0036211;primary metabolic process#GO:0044238;protein modification by small protein conjugation#GO:0032446;catabolic process#GO:0009056 ubiquitin-protein ligase#PC00234 IXOSC|EnsemblGenome=LOC8032446|UniProtKB=A0ACM8DJF4 A0ACM8DJF4 LOC8032446 PTHR11311:SF15 SPONDIN SPONDIN-2 cell adhesion#GO:0007155;cellular process#GO:0009987 external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC8051745|UniProtKB=A0ACM8DLH5 A0ACM8DLH5 LOC8051745 PTHR11803:SF64 2-IMINOBUTANOATE/2-IMINOPROPANOATE DEAMINASE RIDA REACTIVE INTERMEDIATE IMINE DEAMINASE A HOMOLOG hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;deaminase activity#GO:0019239;catalytic activity#GO:0003824 regulation of gene expression#GO:0010468;macromolecule metabolic process#GO:0043170;regulation of biosynthetic process#GO:0009889;post-transcriptional regulation of gene expression#GO:0010608;negative regulation of cellular process#GO:0048523;negative regulation of biosynthetic process#GO:0009890;nucleobase-containing compound metabolic process#GO:0006139;biological regulation#GO:0065007;negative regulation of macromolecule metabolic process#GO:0010605;nucleic acid catabolic process#GO:0141188;nucleobase-containing compound catabolic process#GO:0034655;regulation of primary metabolic process#GO:0080090;regulation of translation#GO:0006417;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;negative regulation of protein metabolic process#GO:0051248;regulation of macromolecule metabolic process#GO:0060255;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;cellular process#GO:0009987;mRNA catabolic process#GO:0006402;negative regulation of macromolecule biosynthetic process#GO:0010558;regulation of protein metabolic process#GO:0051246;RNA metabolic process#GO:0016070;negative regulation of translation#GO:0017148;RNA catabolic process#GO:0006401;mRNA metabolic process#GO:0016071;negative regulation of metabolic process#GO:0009892;regulation of biological process#GO:0050789;negative regulation of biological process#GO:0048519;negative regulation of gene expression#GO:0010629 intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;cellular anatomical structure#GO:0110165;organelle#GO:0043226;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;cytosol#GO:0005829;mitochondrion#GO:0005739 hydrolase#PC00121;metabolite interconversion enzyme#PC00262;deaminase#PC00088 IXOSC|EnsemblGenome=LOC121046965|UniProtKB=A0ACM8FF32 A0ACM8FF32 PTHR21421:SF29 GUSTATORY RECEPTOR GUSTATORY RECEPTOR 5A FOR TREHALOSE-RELATED sensory perception of chemical stimulus#GO:0007606;nervous system process#GO:0050877;sensory perception#GO:0007600;multicellular organismal process#GO:0032501;system process#GO:0003008 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC120846005|UniProtKB=A0ACM8F175 A0ACM8F175 LOC120846005 PTHR23088:SF30 NITRILASE-RELATED OMEGA-AMIDASE NIT2 catalytic activity#GO:0003824;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides#GO:0016811;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810 small molecule metabolic process#GO:0044281;oxoacid metabolic process#GO:0043436;metabolic process#GO:0008152;carboxylic acid metabolic process#GO:0019752;cellular process#GO:0009987 hydrolase#PC00121 IXOSC|EnsemblGenome=LOC115310583|UniProtKB=A0ACM8DPV9 A0ACM8DPV9 LOC115310583 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8041867|UniProtKB=A0ACM8G343 A0ACM8G343 LOC8041867 PTHR24086:SF25 NUCLEAR RECEPTOR SUBFAMILY 5 GROUP A NUCLEAR HORMONE RECEPTOR FTZ-F1 BETA DNA-binding transcription factor#PC00218;gene-specific transcriptional regulator#PC00264;C4 zinc finger nuclear receptor#PC00169;zinc finger transcription factor#PC00244 IXOSC|EnsemblGenome=LOC8042071|UniProtKB=A0ACM8DPL6 A0ACM8DPL6 CSN8 PTHR13339:SF2 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 COP9 SIGNALOSOME COMPLEX SUBUNIT 8 intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;nucleus#GO:0005634;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;COP9 signalosome#GO:0008180;nuclear protein-containing complex#GO:0140513;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8026881|UniProtKB=A0ACM8F8T9 A0ACM8F8T9 PTHR24372:SF74 GLYCOPROTEIN HORMONE RECEPTOR LP13728P signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;peptide receptor activity#GO:0001653;G protein-coupled receptor activity#GO:0004930;G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888 cellular process#GO:0009987;signal transduction#GO:0007165;response to hormone#GO:0009725;biological regulation#GO:0065007;response to chemical#GO:0042221;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;adenylate cyclase-activating G protein-coupled receptor signaling pathway#GO:0007189;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;response to endogenous stimulus#GO:0009719;signaling#GO:0023052;cellular response to hormone stimulus#GO:0032870;regulation of cellular process#GO:0050794;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;G protein-coupled receptor signaling pathway#GO:0007186;cellular response to chemical stimulus#GO:0070887;hormone-mediated signaling pathway#GO:0009755;cell communication#GO:0007154 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC8040553|UniProtKB=A0ACM8DRC1 A0ACM8DRC1 Nmdmc PTHR48099:SF11 C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATED BIFUNCTIONAL METHYLENETETRAHYDROFOLATE DEHYDROGENASE_CYCLOHYDROLASE, MITOCHONDRIAL oxidoreductase activity#GO:0016491;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds#GO:0016810;hydrolase activity#GO:0016787;hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines#GO:0016814;catalytic activity#GO:0003824 tetrahydrofolate metabolic process#GO:0046653;tetrahydrofolate biosynthetic process#GO:0046654;metabolic process#GO:0008152;biosynthetic process#GO:0009058;folic acid-containing compound metabolic process#GO:0006760;pteridine-containing compound metabolic process#GO:0042558;small molecule metabolic process#GO:0044281;cellular process#GO:0009987;modified amino acid metabolic process#GO:0006575 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829 metabolite interconversion enzyme#PC00262 Formyltetrahydrofolate biosynthesis#P02743>Methylene tetrahydrofolate dehydrogenase#P02952 IXOSC|EnsemblGenome=LOC120847499|UniProtKB=A0ACM8F541 A0ACM8F541 PTHR10044:SF183 INHIBITOR OF APOPTOSIS SUBFAMILY NOT NAMED protein-binding activity modulator#PC00095;protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8052042|UniProtKB=A0ACM8EE76 A0ACM8EE76 LOC8052042 PTHR21844:SF2 AKT1 SUBSTRATE 1 PROTEIN PROLINE-RICH AKT1 SUBSTRATE 1 negative regulation of TOR signaling#GO:0032007;regulation of cellular process#GO:0050794;regulation of cell communication#GO:0010646;negative regulation of biological process#GO:0048519;regulation of biological process#GO:0050789;negative regulation of intracellular signal transduction#GO:1902532;negative regulation of cell communication#GO:0010648;negative regulation of signaling#GO:0023057;regulation of intracellular signal transduction#GO:1902531;regulation of signaling#GO:0023051;negative regulation of response to stimulus#GO:0048585;regulation of signal transduction#GO:0009966;biological regulation#GO:0065007;negative regulation of signal transduction#GO:0009968;regulation of TOR signaling#GO:0032006;regulation of TORC1 signaling#GO:1903432;negative regulation of cellular process#GO:0048523;negative regulation of TORC1 signaling#GO:1904262;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 CCKR signaling map#P06959>PRAS40#P07076 IXOSC|EnsemblGenome=LOC120843654|UniProtKB=A0ACM8EWD5 A0ACM8EWD5 LOC120843654 PTHR47980:SF21 LD44762P RE54550P molecular adaptor activity#GO:0060090;protein-macromolecule adaptor activity#GO:0030674;enzyme-substrate adaptor activity#GO:0140767;ubiquitin-like ligase-substrate adaptor activity#GO:1990756 proteasomal protein catabolic process#GO:0010498;vesicle-mediated transport#GO:0016192;cellular process#GO:0009987;exocytosis#GO:0006887;ubiquitin-dependent protein catabolic process#GO:0006511;macromolecule metabolic process#GO:0043170;establishment of localization#GO:0051234;transport#GO:0006810;metabolic process#GO:0008152;macromolecule catabolic process#GO:0009057;proteasome-mediated ubiquitin-dependent protein catabolic process#GO:0043161;export from cell#GO:0140352;catabolic process#GO:0009056;modification-dependent protein catabolic process#GO:0019941;primary metabolic process#GO:0044238;secretion by cell#GO:0032940;localization#GO:0051179;secretion#GO:0046903;protein metabolic process#GO:0019538;protein catabolic process#GO:0030163;modification-dependent macromolecule catabolic process#GO:0043632 plasma membrane#GO:0005886;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;vesicle#GO:0031982;cell periphery#GO:0071944;intracellular vesicle#GO:0097708;membrane#GO:0016020;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;endosome#GO:0005768 IXOSC|EnsemblGenome=LOC115313480|UniProtKB=A0ACM8F5Z6 A0ACM8F5Z6 LOC115313480 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC115332014|UniProtKB=A0ACM8ED73 A0ACM8ED73 LOC115332014 PTHR37984:SF34 PROTEIN CBG26694 GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC115317540|UniProtKB=A0ACM8F2Z1 A0ACM8F2Z1 PTHR42985:SF40 SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER GH19970P-RELATED symporter activity#GO:0015293;secondary active transmembrane transporter activity#GO:0015291;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;active transmembrane transporter activity#GO:0022804 transport#GO:0006810;sodium ion transport#GO:0006814;establishment of localization#GO:0051234;localization#GO:0051179;monoatomic cation transport#GO:0006812;monoatomic ion transport#GO:0006811;metal ion transport#GO:0030001 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 secondary carrier transporter#PC00258;transporter#PC00227 IXOSC|EnsemblGenome=LOC8026034|UniProtKB=A0ACM8FIZ5 A0ACM8FIZ5 LOC8026034 PTHR10264:SF130 BAND 7 PROTEIN-RELATED STOMATIN-LIKE PROTEIN 1 transporter regulator activity#GO:0141108;ion channel inhibitor activity#GO:0008200;ion channel regulator activity#GO:0099106;channel regulator activity#GO:0016247;molecular function regulator activity#GO:0098772;molecular function inhibitor activity#GO:0140678 cell periphery#GO:0071944;membrane#GO:0016020;plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165 cytoskeletal protein#PC00085 IXOSC|EnsemblGenome=LOC8032127|UniProtKB=A0ACM8FH72 A0ACM8FH72 LOC8032127 PTHR19139:SF268 AQUAPORIN TRANSPORTER NEUROGENIC PROTEIN BIG BRAIN water transmembrane transporter activity#GO:0005372;water channel activity#GO:0015250;transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857;passive transmembrane transporter activity#GO:0022803;channel activity#GO:0015267 transport#GO:0006810;establishment of localization#GO:0051234;localization#GO:0051179;water transport#GO:0006833;fluid transport#GO:0042044 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC115331510|UniProtKB=A0ACM8EXZ3 A0ACM8EXZ3 LOC115331510 PTHR22930:SF309 FAMILY NOT NAMED SIMILAR TO ENSANGP00000010363 IXOSC|EnsemblGenome=LOC8025532|UniProtKB=A0ACM8E8N7 A0ACM8E8N7 MAPk-Ak2 PTHR24349:SF561 SERINE/THREONINE-PROTEIN KINASE MAP KINASE-ACTIVATED PROTEIN KINASE 2 catalytic activity#GO:0003824;transferase activity, transferring phosphorus-containing groups#GO:0016772;catalytic activity, acting on a protein#GO:0140096;transferase activity#GO:0016740;calmodulin binding#GO:0005516;kinase activity#GO:0016301;mitogen-activated protein kinase binding#GO:0051019;binding#GO:0005488;kinase binding#GO:0019900;protein serine/threonine kinase activity#GO:0004674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;calcium/calmodulin-dependent protein kinase activity#GO:0004683;phosphotransferase activity, alcohol group as acceptor#GO:0016773;protein binding#GO:0005515;protein kinase activity#GO:0004672 intracellular signal transduction#GO:0035556;cell communication#GO:0007154;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;signal transduction#GO:0007165;regulation of biological process#GO:0050789;biological regulation#GO:0065007;signaling#GO:0023052;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nucleus#GO:0005634;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;organelle#GO:0043226;cellular anatomical structure#GO:0110165 protein modifying enzyme#PC00260;non-receptor serine/threonine protein kinase#PC00167 Angiogenesis#P00005>MAPKAPK2/3#P00244;Ras Pathway#P04393>MAPKAP#P04564;VEGF signaling pathway#P00056>MAPKAPK2/3#P01415;PDGF signaling pathway#P00047>MAPKAPK2#P01157 IXOSC|EnsemblGenome=LOC8043263|UniProtKB=A0ACM8DL28 A0ACM8DL28 Tmep PTHR23423:SF17 ORGANIC SOLUTE TRANSPORTER-RELATED IP17403P transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;membrane#GO:0016020 transporter#PC00227 IXOSC|EnsemblGenome=LOC8031965|UniProtKB=A0ACM8E849 A0ACM8E849 LOC8031965 PTHR24243:SF240 G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTORS FAMILY 1 PROFILE DOMAIN-CONTAINING PROTEIN transmembrane signaling receptor activity#GO:0004888;signaling receptor activity#GO:0038023;molecular transducer activity#GO:0060089;G protein-coupled receptor activity#GO:0004930 G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;biological regulation#GO:0065007;signaling#GO:0023052 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC115312542|UniProtKB=A0ACM8DRU9 A0ACM8DRU9 LOC115312542 PTHR45640:SF13 HEAT SHOCK PROTEIN HSP-12.2-RELATED PROTEIN LETHAL(2)ESSENTIAL FOR LIFE protein refolding#GO:0042026;protein metabolic process#GO:0019538;response to abiotic stimulus#GO:0009628;primary metabolic process#GO:0044238;protein folding#GO:0006457;response to stimulus#GO:0050896;metabolic process#GO:0008152;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;response to heat#GO:0009408;response to stress#GO:0006950;biosynthetic process#GO:0009058;response to temperature stimulus#GO:0009266;gene expression#GO:0010467;protein maturation#GO:0051604 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634 chaperone#PC00072 Angiogenesis#P00005>HSP27#P00231;VEGF signaling pathway#P00056>HSP27#P01412 IXOSC|EnsemblGenome=LOC115324839|UniProtKB=A0ACM8E4C4 A0ACM8E4C4 LOC115324839 PTHR12436:SF38 80 KDA MCM3-ASSOCIATED PROTEIN SAC3 DOMAIN-CONTAINING PROTEIN 1 cellular component organization#GO:0016043;membraneless organelle assembly#GO:0140694;cell cycle process#GO:0022402;centrosome cycle#GO:0007098;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;gene expression#GO:0010467;cellular component assembly#GO:0022607;cytoskeleton organization#GO:0007010;spindle assembly#GO:0051225;cellular component biogenesis#GO:0044085;organelle organization#GO:0006996;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;centrosome duplication#GO:0051298;microtubule organizing center organization#GO:0031023;metabolic process#GO:0008152;chromosome segregation#GO:0007059;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;cell cycle#GO:0007049;nucleic acid transport#GO:0050657;microtubule cytoskeleton organization#GO:0000226;localization#GO:0051179;nuclear export#GO:0051168;nuclear transport#GO:0051169;organelle assembly#GO:0070925;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;macromolecule biosynthetic process#GO:0009059;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;spindle organization#GO:0007051;RNA export from nucleus#GO:0006405;intracellular transport#GO:0046907;transport#GO:0006810 intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle#GO:0043226;cellular anatomical structure#GO:0110165;transcription export complex 2#GO:0070390;intracellular membrane-bounded organelle#GO:0043231;centrosome#GO:0005813;microtubule organizing center#GO:0005815;spindle#GO:0005819;cytoskeleton#GO:0005856;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;microtubule cytoskeleton#GO:0015630;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;cytoplasm#GO:0005737 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120842711|UniProtKB=A0ACM8EU81 A0ACM8EU81 LOC120842711 PTHR47331:SF15 PHD-TYPE DOMAIN-CONTAINING PROTEIN PEPTIDASE A2 DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115308954|UniProtKB=A0ACM8F2C4 A0ACM8F2C4 LOC115308954 PTHR37558:SF2 HTH CENPB-TYPE DOMAIN-CONTAINING PROTEIN SUBFAMILY NOT NAMED IXOSC|EnsemblGenome=LOC115314568|UniProtKB=A0ACM8FT63 A0ACM8FT63 LOC115314568 PTHR21301:SF15 REVERSE TRANSCRIPTASE REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237;reverse transcriptase#PC00200 IXOSC|EnsemblGenome=LOC120842864|UniProtKB=A0ACM8EUN5 A0ACM8EUN5 PTHR31751:SF7 SI:CH211-108C17.2-RELATED-RELATED 6-PHOSPHOFRUCTO-2-KINASE_FRUCTOSE-2, 6-BISPHOSPHATASE 2A ISOFORM X1-RELATED IXOSC|EnsemblGenome=LOC8034637|UniProtKB=A0ACM8EB09 A0ACM8EB09 LOC8034637 PTHR24332:SF9 HOMEOBOX PROTEIN CDX HOMEOTIC PROTEIN CAUDAL DNA binding#GO:0003677;transcription regulatory region nucleic acid binding#GO:0001067;double-stranded DNA binding#GO:0003690;RNA polymerase II transcription regulatory region sequence-specific DNA binding#GO:0000977;nucleic acid binding#GO:0003676;DNA-binding transcription factor activity#GO:0003700;binding#GO:0005488;transcription cis-regulatory region binding#GO:0000976;transcription regulator activity#GO:0140110;sequence-specific double-stranded DNA binding#GO:1990837;sequence-specific DNA binding#GO:0043565 regulation of DNA-templated transcription#GO:0006355;anatomical structure development#GO:0048856;system development#GO:0048731;regulation of RNA metabolic process#GO:0051252;animal gross anatomical part developmental process#GO:0160108;pattern specification process#GO:0007389;regulation of transcription by RNA polymerase II#GO:0006357;cell differentiation#GO:0030154;regulation of macromolecule metabolic process#GO:0060255;regulation of cellular process#GO:0050794;regulation of biological process#GO:0050789;multicellular organism development#GO:0007275;anterior/posterior axis specification#GO:0009948;cellular developmental process#GO:0048869;regulation of biosynthetic process#GO:0009889;regulation of gene expression#GO:0010468;anterior/posterior pattern specification#GO:0009952;developmental process#GO:0032502;regulation of nucleobase-containing compound metabolic process#GO:0019219;multicellular organismal process#GO:0032501;regionalization#GO:0003002;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;tube development#GO:0035295;embryo development#GO:0009790;embryonic pattern specification#GO:0009880;regulation of primary metabolic process#GO:0080090;regulation of macromolecule biosynthetic process#GO:0010556;regulation of metabolic process#GO:0019222;cellular process#GO:0009987 membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular organelle#GO:0043229;nucleus#GO:0005634 helix-turn-helix transcription factor#PC00116;homeodomain transcription factor#PC00119;gene-specific transcriptional regulator#PC00264 IXOSC|EnsemblGenome=LOC8027414|UniProtKB=A0ACM8DYB8 A0ACM8DYB8 LOC8027414 PTHR23158:SF33 MELANOMA INHIBITORY ACTIVITY-RELATED TRANSPORT AND GOLGI ORGANIZATION PROTEIN 1 membrane traffic protein#PC00150 IXOSC|EnsemblGenome=LOC8037844|UniProtKB=A0ACM8E7D3 A0ACM8E7D3 MED8 PTHR13074:SF9 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 8 general transcription factor#PC00259 IXOSC|EnsemblGenome=LOC120850758|UniProtKB=A0ACM8FAU0 A0ACM8FAU0 PTHR47160:SF11 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120839400|UniProtKB=A0ACM8FXR6 A0ACM8FXR6 LOC120839400 PTHR11999:SF70 GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE MIP05841P decarboxylase#PC00089;lyase#PC00144 Adrenaline and noradrenaline biosynthesis#P00001>DOPA decarb.#P00066;5-Hydroxytryptamine biosynthesis#P04371>Aromatic L-amino acid decarboxylase#P04400;Dopamine receptor mediated signaling pathway#P05912>DOPA decarb.#P05961 IXOSC|EnsemblGenome=LOC115317982|UniProtKB=A0ACM8DY35 A0ACM8DY35 PTHR48597:SF1 CCHC-TYPE DOMAIN-CONTAINING PROTEIN CCHC-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8034694|UniProtKB=A0ACM8DZ11 A0ACM8DZ11 LOC8034694 PTHR10075:SF130 BASIGIN RELATED NEURAL CELL ADHESION MOLECULE L1 cell adhesion molecule#PC00069 IXOSC|EnsemblGenome=LOC115319015|UniProtKB=A0ACM8ESG0 A0ACM8ESG0 PTHR36981:SF15 ZGC:195170 P2X PURINORECEPTOR 7 INTRACELLULAR DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8025899|UniProtKB=A0ACM8DNR4 A0ACM8DNR4 LOC8025899 PTHR10334:SF606 CYSTEINE-RICH SECRETORY PROTEIN-RELATED GOLGI-ASSOCIATED PLANT PATHOGENESIS-RELATED PROTEIN 1-LIKE extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 defense/immunity protein#PC00090 IXOSC|EnsemblGenome=LOC8039529|UniProtKB=A0ACM8E330 A0ACM8E330 LOC8039529 PTHR12436:SF39 80 KDA MCM3-ASSOCIATED PROTEIN GERMINAL-CENTER ASSOCIATED NUCLEAR PROTEIN mRNA transport#GO:0051028;establishment of RNA localization#GO:0051236;RNA localization#GO:0006403;RNA transport#GO:0050658;nucleobase-containing compound transport#GO:0015931;nuclear export#GO:0051168;nuclear transport#GO:0051169;mRNA export from nucleus#GO:0006406;cellular localization#GO:0051641;nucleic acid transport#GO:0050657;localization#GO:0051179;nucleocytoplasmic transport#GO:0006913;biosynthetic process#GO:0009058;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;establishment of localization#GO:0051234;macromolecule metabolic process#GO:0043170;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152 organelle#GO:0043226;transcription export complex 2#GO:0070390;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;nucleus#GO:0005634;nuclear protein-containing complex#GO:0140513;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC120850429|UniProtKB=A0ACM8F9Z4 A0ACM8F9Z4 LOC120850429 PTHR11733:SF250 ZINC METALLOPROTEASE FAMILY M13 NEPRILYSIN-RELATED FI07649P-RELATED catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237;hydrolase activity#GO:0016787;catalytic activity, acting on a protein#GO:0140096;metalloendopeptidase activity#GO:0004222;endopeptidase activity#GO:0004175;peptidase activity#GO:0008233 metabolic process#GO:0008152;proteolysis#GO:0006508;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;cellular process#GO:0009987;protein processing#GO:0016485;macromolecule biosynthetic process#GO:0009059;primary metabolic process#GO:0044238;biosynthetic process#GO:0009058;protein maturation#GO:0051604;gene expression#GO:0010467 membrane#GO:0016020;cell periphery#GO:0071944;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115317369|UniProtKB=A0ACM8DX31 A0ACM8DX31 LOC115317369 PTHR24302:SF51 CYTOCHROME P450 FAMILY 3 CYTOCHROME P450 6A18-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC120836966|UniProtKB=A0ACM8EFV7 A0ACM8EFV7 LOC120836966 PTHR46888:SF20 ZINC KNUCKLE DOMAINCONTAINING PROTEIN-RELATED GYPSY RETROTRANSPOSON INTEGRASE-LIKE PROTEIN 1 IXOSC|EnsemblGenome=LOC8023160|UniProtKB=A0ACM8E841 A0ACM8E841 LOC8023160 PTHR10799:SF923 SNF2/RAD54 HELICASE FAMILY PROLIFERATION-ASSOCIATED SNF2-LIKE PROTEIN ATP-dependent activity, acting on DNA#GO:0008094;DNA binding#GO:0003677;ATP-dependent activity#GO:0140657;chromatin binding#GO:0003682;binding#GO:0005488;nucleic acid binding#GO:0003676;catalytic activity, acting on DNA#GO:0140097;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824 regulation of RNA metabolic process#GO:0051252;regulation of DNA-templated transcription#GO:0006355;positive regulation of biosynthetic process#GO:0009891;heterochromatin formation#GO:0031507;positive regulation of RNA metabolic process#GO:0051254;regulation of cellular process#GO:0050794;regulation of macromolecule metabolic process#GO:0060255;negative regulation of cellular process#GO:0048523;regulation of gene expression#GO:0010468;regulation of biosynthetic process#GO:0009889;negative regulation of macromolecule metabolic process#GO:0010605;positive regulation of cellular process#GO:0048522;epigenetic regulation of gene expression#GO:0040029;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of primary metabolic process#GO:0080090;biological regulation#GO:0065007;negative regulation of biosynthetic process#GO:0009890;chromatin organization#GO:0006325;regulation of RNA biosynthetic process#GO:2001141;positive regulation of RNA biosynthetic process#GO:1902680;positive regulation of DNA-templated transcription#GO:0045893;regulation of nucleobase-containing compound metabolic process#GO:0019219;positive regulation of metabolic process#GO:0009893;positive regulation of macromolecule biosynthetic process#GO:0010557;regulation of biological process#GO:0050789;negative regulation of gene expression#GO:0010629;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;chromatin remodeling#GO:0006338;negative regulation of metabolic process#GO:0009892;regulation of transcription by RNA polymerase II#GO:0006357;positive regulation of transcription by RNA polymerase II#GO:0045944;negative regulation of gene expression, epigenetic#GO:0045814;cellular component organization or biogenesis#GO:0071840;cellular process#GO:0009987;positive regulation of biological process#GO:0048518;negative regulation of macromolecule biosynthetic process#GO:0010558;cellular component biogenesis#GO:0044085;heterochromatin organization#GO:0070828;positive regulation of macromolecule metabolic process#GO:0010604;cellular component assembly#GO:0022607 intracellular membraneless organelle#GO:0043232;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nucleus#GO:0005634;chromatin#GO:0000785;chromosome#GO:0005694;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA helicase#PC00011 Wnt signaling pathway#P00057>SWI/SNF#P01435 IXOSC|EnsemblGenome=LOC121834156|UniProtKB=A0ACM8FQ93 A0ACM8FQ93 PTHR36981:SF18 ZGC:195170 P2X PURINOCEPTOR 7 IXOSC|EnsemblGenome=LOC8053869|UniProtKB=A0ACM8E198 A0ACM8E198 PTHR24092:SF5 PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE PHOSPHOLIPID-TRANSPORTING ATPASE intramembrane lipid carrier activity#GO:0140303;molecular carrier activity#GO:0140104;lipid carrier activity#GO:0005319;ATPase-coupled intramembrane lipid carrier activity#GO:0140326;ATP-dependent activity#GO:0140657;transporter activity#GO:0005215 cellular component organization or biogenesis#GO:0071840;import into cell#GO:0098657;establishment of localization#GO:0051234;regulation of membrane lipid distribution#GO:0097035;transport#GO:0006810;Golgi vesicle transport#GO:0048193;lipid transport#GO:0006869;vesicle-mediated transport#GO:0016192;phospholipid transport#GO:0015914;phospholipid translocation#GO:0045332;membrane organization#GO:0061024;biological regulation#GO:0065007;macromolecule localization#GO:0033036;retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum#GO:0006890;cellular process#GO:0009987;localization#GO:0051179;regulation of biological quality#GO:0065008;lipid localization#GO:0010876;organophosphate ester transport#GO:0015748;endocytosis#GO:0006897;lipid translocation#GO:0034204;cellular component organization#GO:0016043 Golgi apparatus subcompartment#GO:0098791;membrane#GO:0016020;cell periphery#GO:0071944;endomembrane system#GO:0012505;cytoplasm#GO:0005737;trans-Golgi network#GO:0005802;plasma membrane#GO:0005886;Golgi apparatus#GO:0005794;intracellular vesicle#GO:0097708;vesicle#GO:0031982;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;endosome#GO:0005768;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;cytoplasmic vesicle#GO:0031410;membrane-bounded organelle#GO:0043227;organelle subcompartment#GO:0031984 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC120836696|UniProtKB=A0ACM8FCG9 A0ACM8FCG9 LOC120836696 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC121047805|UniProtKB=A0ACM8FHV2 A0ACM8FHV2 LOC121047805 PTHR33327:SF4 ENDONUCLEASE ENDONUCLEASE IXOSC|EnsemblGenome=LOC8039405|UniProtKB=A0ACM8E0B7 A0ACM8E0B7 LOC8039405 PTHR13806:SF47 FLOTILLIN-RELATED FLOTILLIN-1 regulation of transport#GO:0051049;regulation of localization#GO:0032879;regulation of endocytosis#GO:0030100;positive regulation of cellular component organization#GO:0051130;biological regulation#GO:0065007;regulation of receptor-mediated endocytosis#GO:0048259;positive regulation of endocytosis#GO:0045807;regulation of cellular component organization#GO:0051128;regulation of cellular process#GO:0050794;positive regulation of transport#GO:0051050;positive regulation of cellular process#GO:0048522;positive regulation of biological process#GO:0048518;regulation of biological process#GO:0050789;regulation of vesicle-mediated transport#GO:0060627 plasma membrane raft#GO:0044853;membrane-bounded organelle#GO:0043227;cytoplasmic vesicle#GO:0031410;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;intracellular vesicle#GO:0097708;membrane protein complex#GO:0098796;membrane raft#GO:0045121;vesicle#GO:0031982;plasma membrane protein complex#GO:0098797;membrane microdomain#GO:0098857;plasma membrane region#GO:0098590;protein-containing complex#GO:0032991;plasma membrane#GO:0005886;cytoplasm#GO:0005737;membrane#GO:0016020;caveola#GO:0005901;cell periphery#GO:0071944 IXOSC|EnsemblGenome=LOC115317152|UniProtKB=A0ACM8EH62 A0ACM8EH62 LOC115317152 PTHR24292:SF105 CYTOCHROME P450 CYTOCHROME P450 6A16, ISOFORM B-RELATED oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8029916|UniProtKB=A0ACM8FTT9 A0ACM8FTT9 tho2 PTHR21597:SF0 THO2 PROTEIN THO COMPLEX SUBUNIT 2 RNA binding#GO:0003723;mRNA binding#GO:0003729;nucleic acid binding#GO:0003676;binding#GO:0005488 establishment of RNA localization#GO:0051236;mRNA transport#GO:0051028;RNA transport#GO:0050658;RNA localization#GO:0006403;nucleobase-containing compound transport#GO:0015931;nucleocytoplasmic transport#GO:0006913;nuclear export#GO:0051168;nuclear transport#GO:0051169;mRNA export from nucleus#GO:0006406;nucleic acid transport#GO:0050657;cellular localization#GO:0051641;localization#GO:0051179;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;establishment of localization in cell#GO:0051649;nitrogen compound transport#GO:0071705;macromolecule localization#GO:0033036;biosynthetic process#GO:0009058;gene expression#GO:0010467;transport#GO:0006810;intracellular transport#GO:0046907;RNA export from nucleus#GO:0006405;metabolic process#GO:0008152;establishment of localization#GO:0051234;poly(A)+ mRNA export from nucleus#GO:0016973;macromolecule metabolic process#GO:0043170 transcription export complex#GO:0000346;intracellular organelle#GO:0043229;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;nucleus#GO:0005634;THO complex#GO:0000347;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 transcription cofactor#PC00217 IXOSC|EnsemblGenome=LOC115326369|UniProtKB=A0ACM8E5U2 A0ACM8E5U2 LOC115326369 PTHR47959:SF25 ATP-DEPENDENT RNA HELICASE RHLE-RELATED ATP-DEPENDENT RNA HELICASE DDX49-RELATED RNA helicase#PC00032 IXOSC|EnsemblGenome=LOC120843768|UniProtKB=A0ACM8EWL3 A0ACM8EWL3 PTHR19143:SF475 FIBRINOGEN/TENASCIN/ANGIOPOEITIN FIBRINOGEN C-TERMINAL DOMAIN-CONTAINING PROTEIN cellular anatomical structure#GO:0110165;external encapsulating structure#GO:0030312;extracellular matrix#GO:0031012;extracellular region#GO:0005576 intercellular signal molecule#PC00207 IXOSC|EnsemblGenome=LOC8024870|UniProtKB=A0ACM8FB08 A0ACM8FB08 LOC8024870 PTHR13316:SF0 ZINC FINGER, CCHC DOMAIN CONTAINING 8 ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 8 binding#GO:0005488;nucleic acid binding#GO:0003676;RNA binding#GO:0003723 RNA metabolic process#GO:0016070;macromolecule metabolic process#GO:0043170;nucleobase-containing compound biosynthetic process#GO:0034654;metabolic process#GO:0008152;nucleic acid biosynthetic process#GO:0141187;gene expression#GO:0010467;biosynthetic process#GO:0009058;RNA biosynthetic process#GO:0032774;RNA processing#GO:0006396;nucleobase-containing compound metabolic process#GO:0006139;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987 intracellular organelle#GO:0043229;catalytic complex#GO:1902494;ribonucleoprotein complex#GO:1990904;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;nuclear protein-containing complex#GO:0140513;catalytic step 2 spliceosome#GO:0071013;nucleus#GO:0005634;spliceosomal complex#GO:0005681;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;protein-containing complex#GO:0032991 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8038477|UniProtKB=A0ACM8DK77 A0ACM8DK77 PTPMT1 PTHR46712:SF1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 PHOSPHATIDYLGLYCEROPHOSPHATASE AND PROTEIN-TYROSINE PHOSPHATASE 1 phosphoric ester hydrolase activity#GO:0042578;hydrolase activity#GO:0016787;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phosphatase activity#GO:0016791 IXOSC|EnsemblGenome=LOC8023783|UniProtKB=A0ACM8E1V0 A0ACM8E1V0 gry PTHR14374:SF1 FOIE GRAS TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 11 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 IXOSC|EnsemblGenome=LOC120841379|UniProtKB=A0ACM8ESJ8 A0ACM8ESJ8 LOC120841379 PTHR11905:SF263 ADAM A DISINTEGRIN AND METALLOPROTEASE DOMAIN ADAM METALLOPROTEASE catalytic activity, acting on a protein#GO:0140096;hydrolase activity#GO:0016787;peptidase activity#GO:0008233;endopeptidase activity#GO:0004175;metalloendopeptidase activity#GO:0004222;catalytic activity#GO:0003824;metallopeptidase activity#GO:0008237 metabolic process#GO:0008152;proteolysis#GO:0006508;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538 protease#PC00190;metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC115326409|UniProtKB=A0ACM8G2R5 A0ACM8G2R5 LOC115326409 PTHR11161:SF0 O-ACYLTRANSFERASE O-ACYLTRANSFERASE LIKE PROTEIN acyltransferase#PC00042 IXOSC|EnsemblGenome=LOC8025424|UniProtKB=A0ACM8DRE3 A0ACM8DRE3 PTHR10971:SF36 MRNA EXPORT FACTOR AND BUB3 MITOTIC CHECKPOINT PROTEIN BUB3 binding#GO:0005488;ubiquitin binding#GO:0043130;protein binding#GO:0005515 negative regulation of chromosome segregation#GO:0051985;negative regulation of metaphase/anaphase transition of cell cycle#GO:1902100;regulation of chromosome segregation#GO:0051983;negative regulation of mitotic sister chromatid segregation#GO:0033048;negative regulation of cell cycle#GO:0045786;negative regulation of sister chromatid segregation#GO:0033046;mitotic spindle assembly checkpoint signaling#GO:0007094;signal transduction#GO:0007165;cellular process#GO:0009987;cell cycle checkpoint signaling#GO:0000075;negative regulation of mitotic cell cycle phase transition#GO:1901991;regulation of chromosome separation#GO:1905818;regulation of cell cycle process#GO:0010564;negative regulation of mitotic sister chromatid separation#GO:2000816;regulation of mitotic cell cycle phase transition#GO:1901990;negative regulation of mitotic cell cycle#GO:0045930;negative regulation of biological process#GO:0048519;negative regulation of cell cycle phase transition#GO:1901988;negative regulation of mitotic nuclear division#GO:0045839;regulation of biological process#GO:0050789;regulation of organelle organization#GO:0033043;cell cycle process#GO:0022402;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;regulation of cell cycle#GO:0051726;signaling#GO:0023052;regulation of sister chromatid segregation#GO:0033045;regulation of chromosome organization#GO:0033044;negative regulation of cellular process#GO:0048523;negative regulation of cell cycle process#GO:0010948;regulation of mitotic sister chromatid separation#GO:0010965;regulation of mitotic nuclear division#GO:0007088;mitotic cell cycle process#GO:1903047;negative regulation of chromosome separation#GO:1905819;regulation of mitotic cell cycle#GO:0007346;regulation of mitotic metaphase/anaphase transition#GO:0030071;biological regulation#GO:0065007;negative regulation of nuclear division#GO:0051784;regulation of nuclear division#GO:0051783;negative regulation of chromosome organization#GO:2001251;cell communication#GO:0007154;intracellular signal transduction#GO:0035556;regulation of mitotic sister chromatid segregation#GO:0033047;mitotic cell cycle checkpoint signaling#GO:0007093;regulation of cell cycle phase transition#GO:1901987;cell cycle#GO:0007049;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;negative regulation of mitotic metaphase/anaphase transition#GO:0045841;cellular response to stimulus#GO:0051716;regulation of metaphase/anaphase transition of cell cycle#GO:1902099;mitotic cell cycle#GO:0000278;regulation of cellular process#GO:0050794 nucleus#GO:0005634;condensed chromosome, centromeric region#GO:0000779;membrane-enclosed lumen#GO:0031974;intracellular membraneless organelle#GO:0043232;supramolecular complex#GO:0099080;protein-containing complex#GO:0032991;chromosome, centromeric region#GO:0000775;condensed chromosome#GO:0000793;nuclear protein-containing complex#GO:0140513;membraneless organelle#GO:0043228;kinetochore#GO:0000776;chromosome#GO:0005694;organelle lumen#GO:0043233;intracellular membrane-bounded organelle#GO:0043231;nucleoplasm#GO:0005654;organelle#GO:0043226;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;intracellular organelle#GO:0043229;intracellular organelle lumen#GO:0070013;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;chromosomal region#GO:0098687 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC8026134|UniProtKB=A0ACM8E0C6 A0ACM8E0C6 FoxK PTHR45881:SF7 CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED CHECKPOINT SUPPRESSOR 1-LIKE, ISOFORM A-RELATED IXOSC|EnsemblGenome=LOC8026527|UniProtKB=A0ACM8DY95 A0ACM8DY95 Atpalpha PTHR43294:SF13 SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA SODIUM_POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA ATPase-coupled monoatomic cation transmembrane transporter activity#GO:0019829;ATP-dependent activity#GO:0140657;ATPase-coupled transmembrane transporter activity#GO:0042626;monoatomic cation transmembrane transporter activity#GO:0008324;potassium ion transmembrane transporter activity#GO:0015079;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;active transmembrane transporter activity#GO:0022804;primary active transmembrane transporter activity#GO:0015399;sodium ion transmembrane transporter activity#GO:0015081;metal ion transmembrane transporter activity#GO:0046873;P-type ion transporter activity#GO:0015662;monoatomic ion transmembrane transporter activity#GO:0015075 transmembrane transport#GO:0055085;monoatomic cation transport#GO:0006812;potassium ion homeostasis#GO:0055075;localization#GO:0051179;monoatomic ion transport#GO:0006811;inorganic ion homeostasis#GO:0098771;import across plasma membrane#GO:0098739;inorganic ion import across plasma membrane#GO:0099587;export from cell#GO:0140352;homeostatic process#GO:0042592;metal ion transport#GO:0030001;intracellular monoatomic ion homeostasis#GO:0006873;sodium ion transport#GO:0006814;import into cell#GO:0098657;establishment of localization#GO:0051234;potassium ion import across plasma membrane#GO:1990573;cellular homeostasis#GO:0019725;inorganic cation import across plasma membrane#GO:0098659;intracellular chemical homeostasis#GO:0055082;transport#GO:0006810;intracellular monoatomic cation homeostasis#GO:0030003;monoatomic cation homeostasis#GO:0055080;chemical homeostasis#GO:0048878;potassium ion transport#GO:0006813;monoatomic ion transmembrane transport#GO:0034220;monoatomic cation transmembrane transport#GO:0098655;potassium ion transmembrane transport#GO:0071805;monoatomic ion homeostasis#GO:0050801;cellular process#GO:0009987;sodium ion transmembrane transport#GO:0035725 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 primary active transporter#PC00068;transporter#PC00227 IXOSC|EnsemblGenome=LOC120841824|UniProtKB=A0ACM8ESJ0 A0ACM8ESJ0 LOC120841824 PTHR33939:SF2 PROTEIN CBG22215 TC1-LIKE TRANSPOSASE DDE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115328068|UniProtKB=A0ACM8ENG6 A0ACM8ENG6 LOC115328068 PTHR45620:SF44 PDF RECEPTOR-LIKE PROTEIN-RELATED G-PROTEIN COUPLED RECEPTOR, ORPHAN-RELATED G protein-coupled peptide receptor activity#GO:0008528;transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;peptide receptor activity#GO:0001653;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of biological process#GO:0050789;signal transduction#GO:0007165;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;biological regulation#GO:0065007;signaling#GO:0023052;response to stimulus#GO:0050896;regulation of cellular process#GO:0050794;adenylate cyclase-modulating G protein-coupled receptor signaling pathway#GO:0007188;G protein-coupled receptor signaling pathway#GO:0007186;cell communication#GO:0007154 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC8042887|UniProtKB=A0ACM8DQW3 A0ACM8DQW3 LOC8042887 PTHR11143:SF7 60S RIBOSOMAL PROTEIN L26 FAMILY MEMBER RIBOSOMAL PROTEIN L26 structural molecule activity#GO:0005198;structural constituent of ribosome#GO:0003735 metabolic process#GO:0008152;translation#GO:0006412;macromolecule metabolic process#GO:0043170;protein metabolic process#GO:0019538;primary metabolic process#GO:0044238;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;cytoplasmic translation#GO:0002181;gene expression#GO:0010467;protein biosynthetic process#GO:0160307;biosynthetic process#GO:0009058 ribonucleoprotein complex#GO:1990904;large ribosomal subunit#GO:0015934;intracellular organelle#GO:0043229;membraneless organelle#GO:0043228;intracellular anatomical structure#GO:0005622;cytosol#GO:0005829;cytosolic ribosome#GO:0022626;cytosolic large ribosomal subunit#GO:0022625;ribosome#GO:0005840;organelle#GO:0043226;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;intracellular membraneless organelle#GO:0043232;ribosomal subunit#GO:0044391;cytoplasm#GO:0005737 ribosomal protein#PC00202;translational protein#PC00263 IXOSC|EnsemblGenome=LOC120836491|UniProtKB=A0ACM8EF56 A0ACM8EF56 LOC120836491 PTHR44229:SF4 15-HYDROXYPROSTAGLANDIN DEHYDROGENASE [NAD(+)] CHAIN DEHYDROGENASE_REDUCTASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G02990)-RELATED oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor#GO:0016616;catalytic activity#GO:0003824;oxidoreductase activity, acting on CH-OH group of donors#GO:0016614;oxidoreductase activity#GO:0016491 dehydrogenase#PC00092;metabolite interconversion enzyme#PC00262;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115312866|UniProtKB=A0ACM8DSK0 A0ACM8DSK0 LOC115312866 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC121837027|UniProtKB=A0ACM8G2D5 A0ACM8G2D5 LOC121837027 PTHR48257:SF3 UBIQUITIN-LIKE PROTEASE FAMILY PROFILE DOMAIN-CONTAINING PROTEIN THAP-TYPE DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8033601|UniProtKB=A0ACM8EI59 A0ACM8EI59 LOC8033601 PTHR21824:SF4 TRANSMEMBRANE PROTEIN 177 TRANSMEMBRANE PROTEIN 177 cellular anatomical structure#GO:0110165;membrane#GO:0016020 IXOSC|EnsemblGenome=LOC115317588|UniProtKB=A0ACM8FB24 A0ACM8FB24 LOC115317588 PTHR22954:SF4 RETROVIRAL PROTEASE-RELATED DUF1758 DOMAIN-CONTAINING PROTEIN viral or transposable element protein#PC00237 IXOSC|EnsemblGenome=LOC8035243|UniProtKB=A0ACM8DJS8 A0ACM8DJS8 LOC8035243 PTHR33968:SF1 PROTEIN PET100 HOMOLOG, MITOCHONDRIAL PROTEIN PET100 HOMOLOG, MITOCHONDRIAL cellular component organization or biogenesis#GO:0071840;protein-containing complex organization#GO:0043933;respiratory chain complex IV assembly#GO:0008535;chaperone-mediated protein complex assembly#GO:0051131;mitochondrial respiratory chain complex IV assembly#GO:0033617;cytochrome complex assembly#GO:0017004;cellular component assembly#GO:0022607;mitochondrial respiratory chain complex assembly#GO:0033108;mitochondrion organization#GO:0007005;cellular component organization#GO:0016043;organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;protein-containing complex assembly#GO:0065003 organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;intracellular organelle#GO:0043229;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;membrane#GO:0016020;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967 IXOSC|EnsemblGenome=LOC115314804|UniProtKB=A0ACM8DUH7 A0ACM8DUH7 LOC115314804 PTHR47526:SF8 ATP-DEPENDENT DNA HELICASE SWIM-TYPE DOMAIN-CONTAINING PROTEIN DNA metabolism protein#PC00009 IXOSC|EnsemblGenome=LOC8023864|UniProtKB=A0ACM8F8M5 A0ACM8F8M5 LOC8023864 PTHR21266:SF62 IRON-SULFUR DOMAIN CONTAINING PROTEIN CHOLESTEROL 7-DESATURASE NVD oxidoreductase#PC00176;oxygenase#PC00177 IXOSC|EnsemblGenome=LOC8032070|UniProtKB=A0ACM8EDJ5 A0ACM8EDJ5 LOC8032070 PTHR11977:SF123 VILLIN GELSOLIN phosphatidylinositol phosphate binding#GO:1901981;cytoskeletal protein binding#GO:0008092;phospholipid binding#GO:0005543;protein-containing complex binding#GO:0044877;lipid binding#GO:0008289;phosphatidylinositol bisphosphate binding#GO:1902936;protein binding#GO:0005515;actin filament binding#GO:0051015;actin binding#GO:0003779;small molecule binding#GO:0036094;binding#GO:0005488;anion binding#GO:0043168;ion binding#GO:0043167;phosphatidylinositol-4,5-bisphosphate binding#GO:0005546 actin filament-based process#GO:0030029;negative regulation of protein polymerization#GO:0032272;actin filament capping#GO:0051693;negative regulation of protein-containing complex disassembly#GO:0043242;negative regulation of cytoskeleton organization#GO:0051494;supramolecular fiber organization#GO:0097435;negative regulation of protein-containing complex assembly#GO:0031333;negative regulation of organelle organization#GO:0010639;negative regulation of cellular component organization#GO:0051129;regulation of supramolecular fiber organization#GO:1902903;actin cytoskeleton organization#GO:0030036;regulation of cellular process#GO:0050794;regulation of cytoskeleton organization#GO:0051493;negative regulation of supramolecular fiber organization#GO:1902904;regulation of protein polymerization#GO:0032271;regulation of actin filament depolymerization#GO:0030834;negative regulation of cellular process#GO:0048523;regulation of actin filament-based process#GO:0032970;regulation of protein depolymerization#GO:1901879;actin filament organization#GO:0007015;actin polymerization or depolymerization#GO:0008154;regulation of actin filament organization#GO:0110053;regulation of actin filament polymerization#GO:0030833;negative regulation of protein depolymerization#GO:1901880;biological regulation#GO:0065007;regulation of actin polymerization or depolymerization#GO:0008064;regulation of actin filament length#GO:0030832;negative regulation of actin filament depolymerization#GO:0030835;regulation of biological quality#GO:0065008;regulation of protein-containing complex assembly#GO:0043254;cellular component organization#GO:0016043;negative regulation of biological process#GO:0048519;regulation of organelle organization#GO:0033043;regulation of biological process#GO:0050789;regulation of cellular component size#GO:0032535;regulation of cellular component organization#GO:0051128;regulation of cellular component biogenesis#GO:0044087;negative regulation of actin filament polymerization#GO:0030837;regulation of anatomical structure size#GO:0090066;cellular component organization or biogenesis#GO:0071840;organelle organization#GO:0006996;regulation of protein-containing complex disassembly#GO:0043244;cellular process#GO:0009987;regulation of actin cytoskeleton organization#GO:0032956;cytoskeleton organization#GO:0007010 actin cytoskeleton#GO:0015629;intracellular membraneless organelle#GO:0043232;cellular anatomical structure#GO:0110165;organelle#GO:0043226;intracellular organelle#GO:0043229;cytoskeleton#GO:0005856;intracellular anatomical structure#GO:0005622;membraneless organelle#GO:0043228 actin or actin-binding cytoskeletal protein#PC00041;non-motor actin binding protein#PC00165 FAS signaling pathway#P00020>Gelsolin#P00611 IXOSC|EnsemblGenome=LOC115332991|UniProtKB=A0ACM8EEW0 A0ACM8EEW0 LOC115332991 PTHR10867:SF17 NNMT/PNMT/TEMT FAMILY MEMBER NICOTINAMIDE N-METHYLTRANSFERASE methyltransferase#PC00155;transferase#PC00220 Adrenaline and noradrenaline biosynthesis#P00001>PNMT#P00061 IXOSC|EnsemblGenome=LOC115331672|UniProtKB=A0ACM8G3F4 A0ACM8G3F4 LOC115331672 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8041739|UniProtKB=A0ACM8E545 A0ACM8E545 LOC8041739 PTHR22594:SF16 ASPARTYL/LYSYL-TRNA SYNTHETASE ASPARAGINE--TRNA LIGASE, CYTOPLASMIC catalytic activity, acting on RNA#GO:0140098;catalytic activity, acting on a tRNA#GO:0140101;catalytic activity, acting on a nucleic acid#GO:0140640;catalytic activity#GO:0003824;ligase activity#GO:0016874 primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;protein biosynthetic process#GO:0160307;translation#GO:0006412;RNA metabolic process#GO:0016070;protein metabolic process#GO:0019538;tRNA aminoacylation#GO:0043039;tRNA aminoacylation for protein translation#GO:0006418;cellular process#GO:0009987;macromolecule biosynthetic process#GO:0009059;gene expression#GO:0010467;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;amino acid metabolic process#GO:0006520;metabolic process#GO:0008152;tRNA metabolic process#GO:0006399;macromolecule metabolic process#GO:0043170;amino acid activation#GO:0043038 cellular anatomical structure#GO:0110165;cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622 translational protein#PC00263;aminoacyl-tRNA synthetase#PC00047 IXOSC|EnsemblGenome=LOC8043564|UniProtKB=A0ACM8DW45 A0ACM8DW45 LOC8043564 PTHR21258:SF55 DOCKING PROTEIN RELATED FI23523P1 fibroblast growth factor receptor binding#GO:0005104;signaling receptor complex adaptor activity#GO:0030159;growth factor receptor binding#GO:0070851;molecular adaptor activity#GO:0060090;receptor tyrosine kinase binding#GO:0030971;signaling adaptor activity#GO:0035591;protein binding#GO:0005515;signaling receptor binding#GO:0005102;binding#GO:0005488;protein tyrosine kinase binding#GO:1990782;kinase binding#GO:0019900;protein-macromolecule adaptor activity#GO:0030674;enzyme binding#GO:0019899;protein kinase binding#GO:0019901;transmembrane receptor protein tyrosine kinase adaptor activity#GO:0005068 cell surface receptor protein tyrosine kinase signaling pathway#GO:0007169;enzyme-linked receptor protein signaling pathway#GO:0007167;cell communication#GO:0007154;cellular response to growth factor stimulus#GO:0071363;response to endogenous stimulus#GO:0009719;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;regulation of cellular process#GO:0050794;response to growth factor#GO:0070848;cellular response to endogenous stimulus#GO:0071495;response to stimulus#GO:0050896;signaling#GO:0023052;response to fibroblast growth factor#GO:0071774;cell surface receptor signaling pathway#GO:0007166;cellular process#GO:0009987;cellular response to fibroblast growth factor stimulus#GO:0044344;signal transduction#GO:0007165;fibroblast growth factor receptor signaling pathway#GO:0008543;biological regulation#GO:0065007 scaffold/adaptor protein#PC00226 IXOSC|EnsemblGenome=LOC8029430|UniProtKB=A0ACM8EBW7 A0ACM8EBW7 LOC8029430 PTHR24249:SF406 HISTAMINE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR G-PROTEIN COUPLED RECEPTOR NO9-RELATED transmembrane signaling receptor activity#GO:0004888;G protein-coupled receptor activity#GO:0004930;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cellular process#GO:0050794;response to stimulus#GO:0050896;signaling#GO:0023052;biological regulation#GO:0065007;cellular process#GO:0009987;cellular response to stimulus#GO:0051716;regulation of biological process#GO:0050789;signal transduction#GO:0007165;cell communication#GO:0007154;G protein-coupled receptor signaling pathway#GO:0007186 plasma membrane#GO:0005886;cellular anatomical structure#GO:0110165;cell periphery#GO:0071944;membrane#GO:0016020 G-protein coupled receptor#PC00021 IXOSC|EnsemblGenome=LOC120838883|UniProtKB=A0ACM8ELJ8 A0ACM8ELJ8 PTHR23420:SF31 ADENOSYLHOMOCYSTEINASE ADENOSYLHOMOCYSTEINASE-LIKE 1-RELATED hydrolase activity#GO:0016787;catalytic activity#GO:0003824 metabolic process#GO:0008152;nucleobase-containing small molecule metabolic process#GO:0055086;carbohydrate derivative metabolic process#GO:1901135;cellular process#GO:0009987;homocysteine metabolic process#GO:0050667;sulfur compound metabolic process#GO:0006790;nucleobase-containing compound metabolic process#GO:0006139;amino acid metabolic process#GO:0006520;proteinogenic amino acid metabolic process#GO:0170039;purine nucleoside metabolic process#GO:0042278;oxoacid metabolic process#GO:0043436;purine-containing compound metabolic process#GO:0072521;primary metabolic process#GO:0044238;modified amino acid metabolic process#GO:0006575;carboxylic acid metabolic process#GO:0019752;small molecule metabolic process#GO:0044281;nucleoside metabolic process#GO:0009116 intracellular anatomical structure#GO:0005622;cytoplasm#GO:0005737;cellular anatomical structure#GO:0110165;cytosol#GO:0005829 hydrolase#PC00121;metabolite interconversion enzyme#PC00262 IXOSC|EnsemblGenome=LOC8029028|UniProtKB=A0ACM8E0J5 A0ACM8E0J5 LOC8029028 PTHR45678:SF5 MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED MITOCHONDRIAL GLUTAMATE CARRIER 2 transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 membrane-bounded organelle#GO:0043227;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;organelle#GO:0043226;cellular anatomical structure#GO:0110165;mitochondrion#GO:0005739;mitochondrial membrane#GO:0031966;organelle inner membrane#GO:0019866;mitochondrial envelope#GO:0005740;mitochondrial inner membrane#GO:0005743;organelle envelope#GO:0031967;membrane#GO:0016020 transporter#PC00227;secondary carrier transporter#PC00258 IXOSC|EnsemblGenome=LOC121835939|UniProtKB=A0ACM8FWF9 A0ACM8FWF9 LOC121835939 PTHR11360:SF284 MONOCARBOXYLATE TRANSPORTER MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED transporter activity#GO:0005215;transmembrane transporter activity#GO:0022857 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 IXOSC|EnsemblGenome=LOC8035950|UniProtKB=A0ACM8FYG7 A0ACM8FYG7 LOC8035950 PTHR22625:SF71 PLEXIN PLEXIN-B transmembrane signaling receptor activity#GO:0004888;molecular transducer activity#GO:0060089;signaling receptor activity#GO:0038023 regulation of cell migration#GO:0030334;positive regulation of developmental process#GO:0051094;regulation of cell differentiation#GO:0045595;neuron projection morphogenesis#GO:0048812;regulation of cell projection organization#GO:0031344;negative regulation of cellular process#GO:0048523;neuron projection guidance#GO:0097485;neurogenesis#GO:0022008;regulation of plasma membrane bounded cell projection organization#GO:0120035;positive regulation of cellular process#GO:0048522;regulation of cell development#GO:0060284;axon guidance#GO:0007411;biological regulation#GO:0065007;regulation of locomotion#GO:0040012;multicellular organismal process#GO:0032501;regulation of cell adhesion#GO:0030155;synapse organization#GO:0050808;positive regulation of cell projection organization#GO:0031346;anatomical structure development#GO:0048856;cellular response to stimulus#GO:0051716;regulation of neurogenesis#GO:0050767;cell junction organization#GO:0034330;regulation of cellular process#GO:0050794;neuron differentiation#GO:0030182;positive regulation of cell differentiation#GO:0045597;cellular component organization or biogenesis#GO:0071840;multicellular organism development#GO:0007275;regulation of anatomical structure morphogenesis#GO:0022603;signal transduction#GO:0007165;positive regulation of biological process#GO:0048518;regulation of neuron projection development#GO:0010975;cellular process#GO:0009987;neuron projection development#GO:0031175;cellular component biogenesis#GO:0044085;positive regulation of cell development#GO:0010720;cell morphogenesis involved in neuron differentiation#GO:0048667;nervous system development#GO:0007399;animal gross anatomical part developmental process#GO:0160108;axonogenesis#GO:0007409;regulation of biological quality#GO:0065008;neuron development#GO:0048666;regulation of biological process#GO:0050789;anatomical structure morphogenesis#GO:0009653;regulation of cell shape#GO:0008360;positive regulation of multicellular organismal process#GO:0051240;cell junction assembly#GO:0034329;negative regulation of biological process#GO:0048519;cell development#GO:0048468;response to stimulus#GO:0050896;regulation of cellular component organization#GO:0051128;synapse assembly#GO:0007416;cell morphogenesis#GO:0000902;developmental process#GO:0032502;cellular developmental process#GO:0048869;axon development#GO:0061564;plasma membrane bounded cell projection organization#GO:0120036;negative regulation of cell adhesion#GO:0007162;system development#GO:0048731;regulation of cell motility#GO:2000145;cell communication#GO:0007154;regulation of nervous system development#GO:0051960;regulation of developmental process#GO:0050793;positive regulation of neurogenesis#GO:0050769;plasma membrane bounded cell projection morphogenesis#GO:0120039;cell surface receptor signaling pathway#GO:0007166;cell projection morphogenesis#GO:0048858;regulation of axonogenesis#GO:0050770;regulation of multicellular organismal process#GO:0051239;cellular component assembly#GO:0022607;generation of neurons#GO:0048699;positive regulation of cellular component organization#GO:0051130;positive regulation of axonogenesis#GO:0050772;regulation of multicellular organismal development#GO:2000026;motor neuron axon guidance#GO:0008045;cellular component organization#GO:0016043;signaling#GO:0023052;cell projection organization#GO:0030030;positive regulation of nervous system development#GO:0051962;cell differentiation#GO:0030154 membrane#GO:0016020;cell periphery#GO:0071944;signaling receptor complex#GO:0043235;protein-containing complex#GO:0032991;cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886 transmembrane signal receptor#PC00197 IXOSC|EnsemblGenome=LOC121836570|UniProtKB=A0ACM8FYQ2 A0ACM8FYQ2 LOC121836570 PTHR46579:SF7 F5/8 TYPE C DOMAIN-CONTAINING PROTEIN-RELATED SLEEPING BEAUTY TRANSPOSASE HTH DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC115330220|UniProtKB=A0ACM8EWS2 A0ACM8EWS2 LOC115330220 PTHR37458:SF1 THISBE THISBE cell communication#GO:0007154;cellular response to stimulus#GO:0051716;cellular process#GO:0009987;signal transduction#GO:0007165;regulation of biological process#GO:0050789;signaling#GO:0023052;biological regulation#GO:0065007;regulation of cellular process#GO:0050794;response to stimulus#GO:0050896 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC120846367|UniProtKB=A0ACM8F1G0 A0ACM8F1G0 LOC120846367 PTHR10174:SF130 ALPHA-TOCOPHEROL TRANSFER PROTEIN-RELATED ALPHA-TOCOPHEROL TRANSFER PROTEIN-LIKE phosphatidylinositol bisphosphate binding#GO:1902936;ion binding#GO:0043167;small molecule binding#GO:0036094;anion binding#GO:0043168;binding#GO:0005488 transfer/carrier protein#PC00219 IXOSC|EnsemblGenome=LOC115322007|UniProtKB=A0ACM8E284 A0ACM8E284 LOC115322007 PTHR36688:SF4 ENDO/EXONUCLEASE/PHOSPHATASE DOMAIN-CONTAINING PROTEIN POL-LIKE PROTEIN IXOSC|EnsemblGenome=LOC8035687|UniProtKB=A0ACM8EAZ4 A0ACM8EAZ4 wol PTHR10859:SF91 GLYCOSYL TRANSFERASE DOLICHYL-PHOSPHATE BETA-GLUCOSYLTRANSFERASE transferase activity#GO:0016740;catalytic activity#GO:0003824;hexosyltransferase activity#GO:0016758;glycosyltransferase activity#GO:0016757;glucosyltransferase activity#GO:0046527 cellular anatomical structure#GO:0110165;endomembrane system#GO:0012505;organelle#GO:0043226;nuclear outer membrane-endoplasmic reticulum membrane network#GO:0042175;intracellular membrane-bounded organelle#GO:0043231;cytoplasm#GO:0005737;membrane#GO:0016020;organelle membrane#GO:0031090;intracellular anatomical structure#GO:0005622;organelle subcompartment#GO:0031984;membrane-bounded organelle#GO:0043227;endoplasmic reticulum membrane#GO:0005789;endoplasmic reticulum#GO:0005783;intracellular organelle#GO:0043229;endoplasmic reticulum subcompartment#GO:0098827 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8039755|UniProtKB=A0ACM8FZT3 A0ACM8FZT3 nompB PTHR44117:SF1 INTRAFLAGELLAR TRANSPORT PROTEIN 88 HOMOLOG NO MECHANORECEPTOR POTENTIAL B, ISOFORM D binding#GO:0005488;cytoskeletal protein binding#GO:0008092;protein binding#GO:0005515 organelle organization#GO:0006996;cellular component biogenesis#GO:0044085;cellular process#GO:0009987;cell projection assembly#GO:0030031;establishment of localization in cell#GO:0051649;cytoskeleton-dependent intracellular transport#GO:0030705;cellular component assembly#GO:0022607;plasma membrane bounded cell projection organization#GO:0120036;intracellular transport#GO:0046907;plasma membrane bounded cell projection assembly#GO:0120031;transport#GO:0006810;establishment of localization#GO:0051234;transport along microtubule#GO:0010970;cellular component organization or biogenesis#GO:0071840;microtubule-based process#GO:0007017;cilium assembly#GO:0060271;cellular component organization#GO:0016043;microtubule-based movement#GO:0007018;cell projection organization#GO:0030030;intraciliary transport#GO:0042073;organelle assembly#GO:0070925;microtubule-based transport#GO:0099111;cellular localization#GO:0051641;non-motile cilium assembly#GO:1905515;localization#GO:0051179;cilium organization#GO:0044782 intracellular organelle#GO:0043229;cilium#GO:0005929;intracellular anatomical structure#GO:0005622;non-motile cilium#GO:0097730;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;plasma membrane bounded cell projection#GO:0120025;cell projection#GO:0042995;cytoskeleton#GO:0005856;ciliary basal body#GO:0036064;microtubule organizing center#GO:0005815;membraneless organelle#GO:0043228;ciliary base#GO:0097546;microtubule cytoskeleton#GO:0015630;centriole#GO:0005814;intracellular membraneless organelle#GO:0043232 IXOSC|EnsemblGenome=LOC115310148|UniProtKB=A0ACM8FI61 A0ACM8FI61 LOC115310148 PTHR47577:SF3 THAP DOMAIN-CONTAINING PROTEIN 6 TRANSPOSABLE ELEMENT P TRANSPOSASE-LIKE RNASE H DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8039663|UniProtKB=A0ACM8DKC8 A0ACM8DKC8 LOC8039663 PTHR21530:SF7 PHEROMONE SHUTDOWN PROTEIN TRAB DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC120843876|UniProtKB=A0ACM8EX18 A0ACM8EX18 LOC120843876 PTHR11929:SF249 ALPHA- 1,3 -FUCOSYLTRANSFERASE FUCOSYLTRANSFERASE glycosyltransferase activity#GO:0016757;alpha-(1->3)-fucosyltransferase activity#GO:0046920;transferase activity#GO:0016740;catalytic activity#GO:0003824;fucosyltransferase activity#GO:0008417;hexosyltransferase activity#GO:0016758 glycosyltransferase#PC00111 IXOSC|EnsemblGenome=LOC8027719|UniProtKB=A0ACM8F8C8 A0ACM8F8C8 LOC8027719 PTHR12192:SF2 CATION TRANSPORT PROTEIN CHAC-RELATED GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2 IXOSC|EnsemblGenome=LOC8039705|UniProtKB=A0ACM8EZ55 A0ACM8EZ55 LOC8039705 PTHR46384:SF1 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2 endomembrane system#GO:0012505;cellular anatomical structure#GO:0110165;organelle#GO:0043226;organelle membrane contact site#GO:0044232 IXOSC|EnsemblGenome=LOC121837161|UniProtKB=A0ACM8G2K3 A0ACM8G2K3 LOC121837161 PTHR11482:SF6 ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE ORNITHINE DECARBOXYLASE 1-RELATED lyase activity#GO:0016829;ornithine decarboxylase activity#GO:0004586;carboxy-lyase activity#GO:0016831;catalytic activity#GO:0003824;carbon-carbon lyase activity#GO:0016830 amine metabolic process#GO:0009308;metabolic process#GO:0008152;cellular process#GO:0009987;polyamine metabolic process#GO:0006595;polyamine biosynthetic process#GO:0006596;biogenic amine metabolic process#GO:0006576;biosynthetic process#GO:0009058 cytoplasm#GO:0005737;intracellular anatomical structure#GO:0005622;cellular anatomical structure#GO:0110165 decarboxylase#PC00089;metabolite interconversion enzyme#PC00262 Ornithine degradation#P02758>Ornithine decarboxylase#P03053 IXOSC|EnsemblGenome=LOC115326181|UniProtKB=A0ACM8E6C4 A0ACM8E6C4 LOC115326181 PTHR13234:SF82 GAMMA-INTERFERON INDUCIBLE LYSOSOMAL THIOL REDUCTASE GILT GAMMA-INTERFERON-INDUCIBLE LYSOSOMAL THIOL REDUCTASE-LIKE PROTEIN oxidoreductase activity#GO:0016491;catalytic activity#GO:0003824 reductase#PC00198;oxidoreductase#PC00176 IXOSC|EnsemblGenome=LOC115323961|UniProtKB=A0ACM8E3H8 A0ACM8E3H8 PTHR33198:SF28 ANK_REP_REGION DOMAIN-CONTAINING PROTEIN-RELATED RETROTRANSPOSON GAG DOMAIN-CONTAINING PROTEIN IXOSC|EnsemblGenome=LOC8032012|UniProtKB=A0ACM8ESQ9 A0ACM8ESQ9 LOC8032012 PTHR24394:SF67 ZINC FINGER PROTEIN MYONEURIN DNA-binding transcription factor activity, RNA polymerase II-specific#GO:0000981;DNA-binding transcription factor activity#GO:0003700;transcription regulator activity#GO:0140110 regulation of primary metabolic process#GO:0080090;regulation of metabolic process#GO:0019222;regulation of macromolecule biosynthetic process#GO:0010556;regulation of biological process#GO:0050789;regulation of nucleobase-containing compound metabolic process#GO:0019219;regulation of macromolecule metabolic process#GO:0060255;regulation of transcription by RNA polymerase II#GO:0006357;regulation of cellular process#GO:0050794;regulation of RNA biosynthetic process#GO:2001141;biological regulation#GO:0065007;regulation of biosynthetic process#GO:0009889;regulation of DNA-templated transcription#GO:0006355;regulation of gene expression#GO:0010468;regulation of RNA metabolic process#GO:0051252 intracellular organelle#GO:0043229;nucleus#GO:0005634;organelle#GO:0043226;cellular anatomical structure#GO:0110165;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular membrane-bounded organelle#GO:0043231 zinc finger transcription factor#PC00244;C2H2 zinc finger transcription factor#PC00248 IXOSC|EnsemblGenome=LOC120836669|UniProtKB=A0ACM8FW18 A0ACM8FW18 LOC120836669 PTHR11705:SF91 PROTEASE FAMILY M14 CARBOXYPEPTIDASE A,B PEPTIDASE M14 CARBOXYPEPTIDASE A DOMAIN-CONTAINING PROTEIN peptidase activity#GO:0008233;catalytic activity, acting on a protein#GO:0140096;metalloexopeptidase activity#GO:0008235;catalytic activity#GO:0003824;carboxypeptidase activity#GO:0004180;hydrolase activity#GO:0016787;metallocarboxypeptidase activity#GO:0004181;exopeptidase activity#GO:0008238;metallopeptidase activity#GO:0008237 protein metabolic process#GO:0019538;macromolecule metabolic process#GO:0043170;cellular process#GO:0009987;primary metabolic process#GO:0044238;proteolysis#GO:0006508;metabolic process#GO:0008152 extracellular region#GO:0005576;cellular anatomical structure#GO:0110165 metalloprotease#PC00153 IXOSC|EnsemblGenome=LOC120842235|UniProtKB=A0ACM8ETB5 A0ACM8ETB5 LOC120842235 PTHR12101:SF1 POPEYE DOMAIN CONTAINING PROTEIN BVES nucleotide binding#GO:0000166;heterocyclic compound binding#GO:1901363;purine ribonucleotide binding#GO:0032555;ribonucleotide binding#GO:0032553;carbohydrate derivative binding#GO:0097367;purine nucleotide binding#GO:0017076;ion binding#GO:0043167;nucleoside phosphate binding#GO:1901265;binding#GO:0005488;small molecule binding#GO:0036094;anion binding#GO:0043168 cellular process#GO:0009987;cell-cell adhesion#GO:0098609;biological regulation#GO:0065007;multicellular organismal process#GO:0032501;heart development#GO:0007507;developmental process#GO:0032502;striated muscle cell differentiation#GO:0051146;animal organ development#GO:0048513;cellular developmental process#GO:0048869;regulation of membrane potential#GO:0042391;multicellular organism development#GO:0007275;muscle cell differentiation#GO:0042692;muscle structure development#GO:0061061;circulatory system development#GO:0072359;cell differentiation#GO:0030154;cell adhesion#GO:0007155;animal gross anatomical part developmental process#GO:0160108;regulation of biological quality#GO:0065008;system development#GO:0048731;anatomical structure development#GO:0048856 apical junction complex#GO:0043296;anchoring junction#GO:0070161;sarcolemma#GO:0042383;cell junction#GO:0030054;tight junction#GO:0070160;cell periphery#GO:0071944;membrane#GO:0016020;cell-cell junction#GO:0005911;plasma membrane#GO:0005886;bicellular tight junction#GO:0005923;cellular anatomical structure#GO:0110165 IXOSC|EnsemblGenome=LOC121837115|UniProtKB=A0ACM8G383 A0ACM8G383 LOC121837115 PTHR24333:SF17 HOMEO BOX HB9 LIKE A-RELATED HOMEOBOX PROTEIN UNPLUGGED-RELATED homeodomain transcription factor#PC00119;helix-turn-helix transcription factor#PC00116 IXOSC|EnsemblGenome=LOC121834420|UniProtKB=A0ACM8FNL0 A0ACM8FNL0 PTHR11472:SF47 DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER FANCONI ANEMIA GROUP J PROTEIN ATP-dependent activity#GO:0140657;ATP-dependent activity, acting on DNA#GO:0008094;macromolecular conformation isomerase activity#GO:0120543;catalytic activity, acting on a nucleic acid#GO:0140640;nucleic acid conformation isomerase activity#GO:0120545;catalytic activity#GO:0003824;DNA helicase activity#GO:0003678;isomerase activity#GO:0016853;helicase activity#GO:0004386;catalytic activity, acting on DNA#GO:0140097 nucleotide-excision repair#GO:0006289;cellular process#GO:0009987;response to stress#GO:0006950;organelle organization#GO:0006996;double-strand break repair#GO:0006302;cellular component organization or biogenesis#GO:0071840;DNA recombination#GO:0006310;DNA metabolic process#GO:0006259;metabolic process#GO:0008152;meiotic cell cycle#GO:0051321;response to stimulus#GO:0050896;cell cycle process#GO:0022402;meiosis I#GO:0007127;meiotic cell cycle process#GO:1903046;cellular component organization#GO:0016043;reciprocal meiotic recombination#GO:0007131;cellular response to stress#GO:0033554;nuclear division#GO:0000280;nucleobase-containing compound metabolic process#GO:0006139;meiotic nuclear division#GO:0140013;macromolecule metabolic process#GO:0043170;DNA damage response#GO:0006974;DNA repair#GO:0006281;reproductive process#GO:0022414;homologous recombination#GO:0035825;cellular response to stimulus#GO:0051716;reciprocal homologous recombination#GO:0140527;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;cell cycle#GO:0007049;organelle fission#GO:0048285;sexual reproduction#GO:0019953;meiosis I cell cycle process#GO:0061982 intracellular membrane-bounded organelle#GO:0043231;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227;cellular anatomical structure#GO:0110165;organelle#GO:0043226;nucleus#GO:0005634;intracellular organelle#GO:0043229 DNA metabolism protein#PC00009;DNA helicase#PC00011 IXOSC|EnsemblGenome=LOC8023167|UniProtKB=A0ACM8E8I6 A0ACM8E8I6 LOC8023167 PTHR15186:SF5 RE48077P BNIP3, ISOFORM A process utilizing autophagic mechanism#GO:0061919;regulation of biological process#GO:0050789;cell death#GO:0008219;apoptotic process#GO:0006915;regulation of programmed cell death#GO:0043067;cellular component organization#GO:0016043;programmed cell death#GO:0012501;catabolic process#GO:0009056;regulation of cellular process#GO:0050794;positive regulation of programmed cell death#GO:0043068;regulation of apoptotic process#GO:0042981;metabolic process#GO:0008152;autophagy of mitochondrion#GO:0000422;positive regulation of apoptotic process#GO:0043065;cellular component organization or biogenesis#GO:0071840;mitophagy#GO:0000423;autophagy#GO:0006914;positive regulation of biological process#GO:0048518;positive regulation of cellular process#GO:0048522;cellular process#GO:0009987;organelle organization#GO:0006996;mitochondrion organization#GO:0007005;biological regulation#GO:0065007;apoptotic mitochondrial changes#GO:0008637;macroautophagy#GO:0016236 intracellular organelle#GO:0043229;outer membrane#GO:0019867;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;organelle envelope#GO:0031967;mitochondrion#GO:0005739;organelle#GO:0043226;cellular anatomical structure#GO:0110165;intracellular membrane-bounded organelle#GO:0043231;mitochondrial outer membrane#GO:0005741;organelle membrane#GO:0031090;bounding membrane of organelle#GO:0098588;membrane#GO:0016020;mitochondrial membrane#GO:0031966;mitochondrial envelope#GO:0005740;nucleus#GO:0005634;organelle outer membrane#GO:0031968;cytoplasm#GO:0005737 IXOSC|EnsemblGenome=LOC115319356|UniProtKB=A0ACM8DZS2 A0ACM8DZS2 LOC115319356 PTHR11461:SF390 SERINE PROTEASE INHIBITOR, SERPIN ACCESSORY GLAND PROTEIN ACP76A-RELATED regulation of immune system process#GO:0002682;biological regulation#GO:0065007;regulation of biological process#GO:0050789;regulation of immune response#GO:0050776;regulation of response to stimulus#GO:0048583 cellular anatomical structure#GO:0110165;extracellular region#GO:0005576 protease inhibitor#PC00191 IXOSC|EnsemblGenome=LOC8035864|UniProtKB=A0ACM8EDL3 A0ACM8EDL3 Sas10 PTHR13237:SF8 SOMETHING ABOUT SILENCING PROTEIN 10-RELATED SOMETHING ABOUT SILENCING PROTEIN 10 RNA biosynthetic process#GO:0032774;maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)#GO:0000462;ribonucleoprotein complex biogenesis#GO:0022613;primary metabolic process#GO:0044238;nucleic acid metabolic process#GO:0090304;rRNA processing#GO:0006364;RNA metabolic process#GO:0016070;nucleic acid biosynthetic process#GO:0141187;ribosome biogenesis#GO:0042254;nucleobase-containing compound metabolic process#GO:0006139;biosynthetic process#GO:0009058;maturation of SSU-rRNA#GO:0030490;RNA processing#GO:0006396;gene expression#GO:0010467;macromolecule biosynthetic process#GO:0009059;cellular process#GO:0009987;cellular component biogenesis#GO:0044085;macromolecule metabolic process#GO:0043170;cellular component organization or biogenesis#GO:0071840;ribosomal small subunit biogenesis#GO:0042274;metabolic process#GO:0008152;nucleobase-containing compound biosynthetic process#GO:0034654;rRNA metabolic process#GO:0016072 membrane-enclosed lumen#GO:0031974;nucleus#GO:0005634;protein-containing complex#GO:0032991;intracellular membraneless organelle#GO:0043232;membraneless organelle#GO:0043228;nuclear protein-containing complex#GO:0140513;organelle lumen#GO:0043233;small-subunit processome#GO:0032040;cellular anatomical structure#GO:0110165;nuclear lumen#GO:0031981;organelle#GO:0043226;intracellular membrane-bounded organelle#GO:0043231;preribosome#GO:0030684;intracellular organelle lumen#GO:0070013;nucleolus#GO:0005730;ribonucleoprotein complex#GO:1990904;intracellular organelle#GO:0043229;intracellular anatomical structure#GO:0005622;membrane-bounded organelle#GO:0043227 RNA metabolism protein#PC00031 IXOSC|EnsemblGenome=LOC120837209|UniProtKB=A0ACM8EHU9 A0ACM8EHU9 LOC120837209 PTHR23428:SF386 HISTONE H2B HISTONE H2B 1-RELATED chromatin/chromatin-binding, or -regulatory protein#PC00077 IXOSC|EnsemblGenome=LOC8029447|UniProtKB=A0ACM8FSP9 A0ACM8FSP9 LOC8029447 PTHR45897:SF4 HIGH-AFFINITY CHOLINE TRANSPORTER 1 HIGH-AFFINITY CHOLINE TRANSPORTER 1 monoatomic ion transmembrane transporter activity#GO:0015075;solute:monoatomic cation symporter activity#GO:0015294;sodium ion transmembrane transporter activity#GO:0015081;active transmembrane transporter activity#GO:0022804;metal ion transmembrane transporter activity#GO:0046873;transmembrane transporter activity#GO:0022857;transporter activity#GO:0005215;secondary active transmembrane transporter activity#GO:0015291;solute:sodium symporter activity#GO:0015370;monoatomic cation transmembrane transporter activity#GO:0008324;symporter activity#GO:0015293 cellular anatomical structure#GO:0110165;plasma membrane#GO:0005886;membrane#GO:0016020;cell periphery#GO:0071944 transporter#PC00227 Muscarinic acetylcholine receptor 1 and 3 signaling pathway#P00042>CHT1#P01072;Nicotinic acetylcholine receptor signaling pathway#P00044>CHT1#P01098;Muscarinic acetylcholine receptor 2 and 4 signaling pathway#P00043>CHT1#P01084 IXOSC|EnsemblGenome=LOC120850541|UniProtKB=A0ACM8FYX3 A0ACM8FYX3 LOC120850541 PTHR33332:SF49 REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN-RELATED IXOSC|EnsemblGenome=LOC8030315|UniProtKB=A0ACM8E9F9 A0ACM8E9F9 LOC8030315 PTHR10340:SF34 SPHINGOMYELIN PHOSPHODIESTERASE SPHINGOMYELIN PHOSPHODIESTERASE phosphoric ester hydrolase activity#GO:0042578;phosphoric diester hydrolase activity#GO:0008081;hydrolase activity#GO:0016787;lipase activity#GO:0016298;catalytic activity#GO:0003824;hydrolase activity, acting on ester bonds#GO:0016788;phospholipase activity#GO:0120569 ceramide metabolic process#GO:0006672;organophosphate catabolic process#GO:0046434;catabolic process#GO:0009056;phospholipid catabolic process#GO:0009395;phospholipid metabolic process#GO:0006644;primary metabolic process#GO:0044238;sphingolipid catabolic process#GO:0030149;phosphorus metabolic process#GO:0006793;sphingolipid biosynthetic process#GO:0030148;metabolic process#GO:0008152;sphingolipid metabolic process#GO:0006665;lipid metabolic process#GO:0006629;ceramide biosynthetic process#GO:0046513;lipid biosynthetic process#GO:0008610;sphingomyelin metabolic process#GO:0006684;biosynthetic process#GO:0009058;organophosphate metabolic process#GO:0019637;cellular process#GO:0009987;lipid catabolic process#GO:0016042 organelle#GO:0043226;cellular anatomical structure#GO:0110165;vacuole#GO:0005773;cytoplasm#GO:0005737;intracellular membrane-bounded organelle#GO:0043231;lysosome#GO:0005764;lytic vacuole#GO:0000323;membrane-bounded organelle#GO:0043227;intracellular anatomical structure#GO:0005622;intracellular organelle#GO:0043229;extracellular region#GO:0005576 phosphodiesterase#PC00185;hydrolase#PC00121 IXOSC|EnsemblGenome=LOC120850221|UniProtKB=A0ACM8F9J4 A0ACM8F9J4 LOC120850221 PTHR34153:SF3 SI:CH211-262H13.3-RELATED-RELATED SI:CH211-262H13.3 IXOSC|EnsemblGenome=LOC115325480|UniProtKB=A0ACM8EYE9 A0ACM8EYE9 LOC115325480 PTHR47160:SF13 PUTATIVE-RELATED MULE TRANSPOSASE DOMAIN-CONTAINING PROTEIN